keyword
https://read.qxmd.com/read/34225532/do-patients-with-a-single-abnormal-ogtt-value-need-a-globally-admitted-definition-such-as-borderline-gdm-pregnancy-outcomes-of-these-women-and-the-evaluation-of-new-inflammatory-markers
#21
JOURNAL ARTICLE
Deniz Simsek, Burak Akselim, Yasin Altekin
INTRODUCTION: One of the approaches to diagnose Gestational Diabetes Mellitus (GDM) is to detect two or more elevated values in 3-h Glucose Tolerance Test (OGTT) after an abnormal 50 gr Glucose Challenge Test (GCT). Patients with single elevated OGTT generally postulated as healthy; however, these patients could experience adverse perinatal and maternal issues more frequently. We aimed to investigate the maternal and neonatal outcomes of women with single abnormal OGTT primarily by comparing these women with healthy controls and GDM patients...
November 2021: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/33884215/diagnostic-value-of-neutrophil-to-lymphocyte-ratio-and-mean-platelet-volume-on-early-onset-neonatal-sepsis-on-term-neonate
#22
JOURNAL ARTICLE
Birol Karabulut, Silem Ozdem Alatas
By setting out from increased neutrophil count, decreased lymphocyte count, and increased mean platelet volume (MPV), which is a result of the effect of inflammation on blood cells, we aimed to investigate whether neutrophil to lymphocyte ratio (NLP) and MPV can be used as an auxiliary parameter for the diagnosis of early-onset neonatal sepsis (EOS). This study was conducted by analyzing term neonates with EOS and physiological jaundice who were admitted to the neonatal intensive care unit of Izmir Katip Celebi University Ataturk Training and Research Hospital...
June 2021: Journal of Pediatric Intensive Care
https://read.qxmd.com/read/33694147/the-effects-of-water-immersion-during-first-stage-of-labor-on-postpartum-systemic-inflammatory-response
#23
JOURNAL ARTICLE
Ayçağ Yorgancı, Gul Nihal Buyuk, Mesut Akyol, Özlem Gündüz, Banu Seven, Yaprak Engin-Ustun
OBJECTIVE: The systemic inflammatory response is a cascade of physiologic reactions that arise in response to trauma, infection, burn, or any kind of injury. This study aimed to determine the effects of water immersion during the first stage of labor on the systemic inflammatory indices in the postpartum period. MATERIALS AND METHODS: In this retrospective study, 125 healthy multiparous women with uncomplicated pregnancies between 37 and 41 weeks of gestation who elected for immersion in water during the first stage of labor were compared with multiparous uncomplicated term women who had conventional vaginal births on land (n=125)...
March 10, 2021: Zeitschrift Für Geburtshilfe und Neonatologie
https://read.qxmd.com/read/33544531/comparison-of-hematological-parameters-and-perinatal-outcomes-between-covid-19-pregnancies-and-healthy-pregnancy-cohort
#24
COMPARATIVE STUDY
Esin Merve Erol Koç, Rahime Bedir Fındık, Hatice Akkaya, Işılay Karadağ, Eda Özden Tokalıoğlu, Özlem Moraloğlu Tekin
OBJECTIVES: To evaluate the relationship between Coronavirus Disease 2019 (COVID-19) in pregnancy and adverse perinatal outcomes. The secondary aim is to analyze the diagnostic value of hematologic parameters in COVID-19 complicated pregnancies. METHODS: The current study is conducted in a high volume tertiary obstetrics center burdened by COVID-19 pandemics, in Turkey. In this cohort study, perinatal outcomes and complete blood count indices performed at the time of admission of 39 pregnancies (Study group) complicated by COVID-19 were compared with 69 uncomplicated pregnancies (Control group)...
February 23, 2021: Journal of Perinatal Medicine
https://read.qxmd.com/read/33342727/investigation-of-neutrophil-lymphocyte-ratio-and-mean-platelet-volume-in-patients-diagnosed-with-preterm-labor
#25
REVIEW
Yüksel Kurban, Yasemin Alan, İbrahim Uyar, Zeliha Atak, Önder Aydemir, Abdulmecit Öktem
BACKGROUND: To investigate the level of neutrophil/lymphocyte ratio (NLO) and mean platelet volume (MPV) in preterm birth in patients who gave birth before 37 weeks. METHOD: This study was conducted by a retrospective examination of the patients who gave birth with preterm labor diagnosis from January 2017 to May 2018 at Ankara Keçiören Training and Research Hospital, Obstetrics and Gynecology Clinic. The study included 138 patients. Patients were divided into three groups: Early Preterm (delivery before 34 weeks, Group I = 39), Late Preterm (delivery between 34 and 37 weeks, Group II = 59) and the Control Group (delivery after 37 weeks, Group III = 40)...
December 2021: Paediatric Respiratory Reviews
https://read.qxmd.com/read/33180448/evaluation-of-the-diagnostic-value-of-peripheral-blood-parameters-for-neonatal-pneumonia
#26
JOURNAL ARTICLE
Dan Liao, Jinmi Li, Jing Lv, Tingting Sun, Shaoli Deng
BACKGROUND: To evaluate the diagnostic value of peripheral blood parameters including white blood cell (WBC), neutrophil, lymphocyte, monocyte, platelet, mean platelet volume (MPV), platelet distribution width (PDW), mean corpuscular volume (MCV), red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte (MLR), platelet-to-lymphocyte ratio (PLR) and platelet-to-neutrophil ratio (PNR) for neonatal pneumonia. METHODS: Two hundred and six full-term neonates in our hospital from January 2018 to December 2019 were enrolled, including 73 pneumonic neonates and 133 health controls...
November 1, 2020: Clinical Laboratory
https://read.qxmd.com/read/32683561/the-effects-of-parenteral-iron-administration-on-thyroid-hormones-hematology-oxidative-stress-characteristics-performance-and-health-in-neonatal-holstein-calves
#27
JOURNAL ARTICLE
Narges Khaleghnia, Mehrdad Mohri, Hesam A Seifi
The present study investigated the effect of iron supplementation on thyroid hormones concentrations, oxidative stress characteristics, complete blood count (CBC) and serum biochemistry, and performance and health in calves of two groups: test group (n = 17, intramuscular injection of 500 mg iron-dextran on the 2nd day of life) and control group (n = 17, intramuscular injection of normal saline at the same time). Blood samples were taken from all of the calves instantly after birth and at 7, 14, 21, 28, and 90 days of age...
May 2021: Biological Trace Element Research
https://read.qxmd.com/read/32206652/is-there-an-association-between-platelet-and-blood-inflammatory-indices-and-the-risk-of-gestational-diabetes-mellitus
#28
JOURNAL ARTICLE
Mahta Abbasi Fashami, Sepideh Hajian, Maryam Afrakhteh, Mehdi Khabaz Khoob
Objective: Gestational diabetes mellitus (GDM) is the most prevalent medical complication in pregnancy. Early diagnosis of GDM can influence maternal/neonatal outcomes. To assess the association between platelet and blood inflammatory indices and the risk of GDM occurrence using the complete blood count (CBC) test. We also aimed to determine the sensitivity of each parameter for an early screening of this disorder during pregnancy. Methods: This case-control study included 2 groups of 110 pregnant women with and without GDM...
March 2020: Obstetrics & Gynecology Science
https://read.qxmd.com/read/32157117/neutrophil-volume-conductivity-and-scatter-vcs-as-a-screening-tool-in-neonatal-sepsis
#29
JOURNAL ARTICLE
Prerana Nesargi, H S Niranjan, Prathik Bandiya, Naveen Benakappa
The initial evaluation of a suspected sepsis in a neonate is always challenging. There are many methods to screen a neonate with suspected sepsis. One of newer method is to assess the changes in neutrophil volume conductivity and scatter. The objective of this study was to establish changes in Neutrophil volume conductivity scatter (VCS) in neonatal sepsis and to determine appropriate cut off levels using receiver operating characteristic (ROC) curves. Neonates with suspected sepsis were evaluated with blood counts, culture and neutrophil VCS parameters...
March 10, 2020: Scientific Reports
https://read.qxmd.com/read/31549538/the-use-of-inflammatory-markers-as-a-diagnostic-and-prognostic-approach-in-neonatal-calves-with-septicaemia
#30
JOURNAL ARTICLE
Akın Kirbas, Fatih Mehmet Kandemir, Demet Celebi, Basak Hanedan, Mehmet Ozkan Timurkan
The objective of this study was to evaluate the usefulness of inflammatory markers as a diagnostic and prognostic approach in neonatal calves with septicaemia. The study material consisted of 13 neonatal calves with septicaemia (septicaemic calves, SC) and ten healthy neonatal calves (control calves, CC). Blood samples were collected for biochemical, haematological and microbiological analyses. In addition, faecal samples were collected for microbiological and virological analyses. Three of neonatal calves with septicaemia were positive for E...
September 2019: Acta Veterinaria Hungarica
https://read.qxmd.com/read/31039810/neonatal-hematological-parameters-and-the-risk-of-moderate-severe-bronchopulmonary-dysplasia-in-extremely-premature-infants
#31
JOURNAL ARTICLE
Xueyu Chen, Huitao Li, Xiaomei Qiu, Chuanzhong Yang, Frans J Walther
OBJECTIVE: To evaluate the association between hematological parameters at birth and the risk of moderate-severe bronchopulmonary dysplasia (BPD) in a cohort of extremely preterm infants. METHODS: This is a retrospective study of all extremely premature infants admitted to the neonatal intensive care unit, Shenzhen Maternity and Child Healthcare Hospital from January 2016 to May 2018. Extremely prematurity was defined as a delivery at a gestational age ≤ 28 weeks or a birth weight ≤ 1000 g...
April 30, 2019: BMC Pediatrics
https://read.qxmd.com/read/30608604/synbiotics-combined-with-glutamine-stimulate-brain-development-and-the-immune-system-in-preterm-pigs
#32
JOURNAL ARTICLE
Anders D Andersen, Duc Ninh Nguyen, Louise Langhorn, Ingrid B Renes, Ruurd M van Elburg, Anita Hartog, Sebastian Tims, Yohan van de Looij, Per T Sangild, Thomas Thymann
Background: Preterm infants are born with an immature gut, brain, and immune system, predisposing them to short- and long-term complications. Objective: We hypothesized that a milk diet supplemented with pre- and probiotics (i.e. synbiotics) and glutamine would improve gut, brain, and immune maturation in preterm neonates, using preterm pigs as a model. Methods: Preterm pigs (Landrace x Yorkshire x Duroc, n = 40, delivered by c-section at 90% of gestation) were reared individually until day 23 after birth under highly standardized conditions...
January 4, 2019: Journal of Nutrition
https://read.qxmd.com/read/30080755/is-mpv-a-predictive-marker-for-neonatal-sepsis-a-pilot-study
#33
JOURNAL ARTICLE
Sridevi B Hanaganahalli, Saraswathy Sreeram, Mytreyi Bompada, Santosh K Kuppannagari, Pooja K Suresh, Cheryl S Philipose
Neonatal sepsis (NS) continues to be a diagnostic challenge and a prime cause of mortality. Forage for a lucid, cost-effective yet highly sensitive and specific marker in diagnosing this entity is an incessant task. This study aimed to evaluate the predictive value of mean platelet volume (MPV) in diagnosing NS. Neonates diagnosed with sepsis from January 2016 to March 2016 were included in the study. The subjects were stratified into the following: (i) culture-proven sepsis (group I); (ii) culture-negative clinical sepsis (group II); and (iii) control group (group III)...
October 2018: Journal of Pediatric Hematology/oncology
https://read.qxmd.com/read/29331737/hematology-reference-intervals-for-neonatal-holstein-calves
#34
JOURNAL ARTICLE
Nikolaos Panousis, Nektarios Siachos, Georgios Kitkas, Emmanouil Kalaitzakis, Maria Kritsepi-Konstantinou, Georgios E Valergakis
Data regarding hematologic reference intervals (RI) for neonatal calves have not been published yet. The aims of this study were: a) to establish hematology RIs for neonatal Holstein calves, b) to compare them with the RIs for lactating cows, and c) to investigate the relationship of age and gender with the hematologic profile of calves. Two-hundred and fifty-four clinically healthy Holstein calves (1-9days old, from 30 farms) and 82 healthy Holstein cows (between 30 and 150days in milk, from 10 farms) were blood sampled once for a complete blood count evaluation, using the ADVIA 120 hematology analyzer...
June 2018: Research in Veterinary Science
https://read.qxmd.com/read/29179639/are-neutrophil-lymphocyte-ratio-nlr-platelet-lymphocyte-ratio-plr-and-or-mean-platelet-volume-mpv-clinically-useful-as-predictive-parameters-for-preeclampsia
#35
JOURNAL ARTICLE
Dominique Mannaerts, Suzanne Heyvaert, Chania De Cordt, Claartje Macken, Charlotte Loos, Yves Jacquemyn
OBJECTIVE: Preeclampsia (PE) is a severe pregnancy complication with significant maternal and neonatal morbi-mortality resulting in high health care costs. Prevention, mainly based on the administration of acetylsalicylic acid, is only possible if timely identification of high-risk patients can be realized in an easy, nonexpensive, and widely available method. This paper explores the clinical usability of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and/or mean platelet volume (MPV) in discriminating between women that will and those that will not develop PE...
May 2019: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/29028152/salivary-c-reactive-protein-and-mean-platelet-volume-in-diagnosis-of-late-onset-neonatal-pneumonia
#36
JOURNAL ARTICLE
Ahmed Omran, Mohammed Ali, Mai H Saleh, Osama Zekry
BACKGROUND: Neonatal pneumonia is an important and major cause of neonatal morbidity and mortality worldwide therefore; its early detection plays a crucial role in successful therapy. Analysis of saliva as a non-invasive method for detection of neonatal diseases holds great promise for improving health care. Till now, salivary C-reactive protein (CRP), mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR) and platelets/lymphocytes ratio (PLR) have not been studied as markers of diagnosis in neonatal pneumonia...
April 2018: Clinical Respiratory Journal
https://read.qxmd.com/read/28892906/changes-in-haematological-parameters-in-newborns-born-to-preeclamptic-mothers-a-case-control-study-in-a-rural-hospital
#37
JOURNAL ARTICLE
Kalavakuru Mouna, Shilpa Manigatta Doddagowda, Krishnappa Junjegowda, Latha Krishnamurthy
INTRODUCTION: Pregnancy is a physiological phenomenon. However, some women develop problems during pregnancy period, which puts both the mother's and the foetus health at risk. Hypertensive disorders of pregnancy are the type of the maternal diseases that can cause the most detrimental effects to the mother and foetus. AIMS: To determine the haematological parameters in neonates born to preeclamptic mothers. MATERIALS AND METHODS: It was a prospective case control study carried out on neonates born to preeclamptic mothers in our institute from March 2016 to November 2016...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://read.qxmd.com/read/28873345/neutrophil-chemotaxis-and-transcriptomics-in-term-and-preterm-neonates
#38
JOURNAL ARTICLE
Steven L Raymond, Brittany J Mathias, Tyler J Murphy, Jaimar C Rincon, María Cecilia López, Ricardo Ungaro, Felix Ellett, Julianne Jorgensen, James L Wynn, Henry V Baker, Lyle L Moldawer, Daniel Irimia, Shawn D Larson
Neutrophils play a crucial role in combating life-threatening bacterial infections in neonates. Previous studies investigating neonatal cell function have been limited because of restricted volume sampling. Here, using novel microfluidic approaches, we provide the first description of neutrophil chemotaxis and transcriptomics from whole blood of human term and preterm neonates, as well as young adults. Ex vivo percent cell migration, neutrophil velocity, and directionality to N-formylmethionyl-leucyl-phenylalanine were measured from whole blood using time-lapse imaging of microfluidic chemotaxis...
December 2017: Translational Research: the Journal of Laboratory and Clinical Medicine
https://read.qxmd.com/read/28734690/salivary-c-reactive-protein-mean-platelet-volume-and-neutrophil-lymphocyte-ratio-as-diagnostic-markers-for-neonatal-sepsis
#39
JOURNAL ARTICLE
Ahmed Omran, Abdallah Maaroof, Mai H S Mohammad, Amina Abdelwahab
OBJECTIVE: To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. METHODS: Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis and 15 with clinical sepsis) and 35 healthy controls. Serum and salivary C-reactive protein concentrations were measured by enzyme-linked immunosorbent assay while mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio were measured by automated blood cell counter...
January 2018: Jornal de Pediatria
https://read.qxmd.com/read/28157226/early-exposure-to-thirdhand-cigarette-smoke-affects-body-mass-and-the-development-of-immunity-in-mice
#40
JOURNAL ARTICLE
Bo Hang, Antoine M Snijders, Yurong Huang, Suzaynn F Schick, Pin Wang, Yankai Xia, Christopher Havel, Peyton Jacob, Neal Benowitz, Hugo Destaillats, Lara A Gundel, Jian-Hua Mao
Thirdhand smoke (THS) is the fraction of cigarette smoke that persists in indoor environments after smoking. We investigated the effects of neonatal and adult THS exposure on bodyweight and blood cell populations in C57BL/6 J mice. At the end of neonatal exposure, THS-treated male and female mice had significantly lower bodyweight than their respective control mice. However, five weeks after neonatal exposure ended, THS-treated mice weighed the same as controls. In contrast, adult THS exposure did not change bodyweight of mice...
February 3, 2017: Scientific Reports
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