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mycoplasma pneumoniae

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https://www.readbyqxmd.com/read/28730137/pediatric-mycoplasma-pneumoniae-infection-presenting-with-acute-cholestatic-hepatitis-and-other-extrapulmonary-manifestations-in-the-absence-of-pneumonia
#1
Won Jae Song, Ben Kang, Hwa Pyung Lee, Joongbum Cho, Hae Jeong Lee, Yon Ho Choe
Mycoplasma pneumoniae infections mainly involve respiratory tract; however, also can manifestate other symptoms by site involved. Extrapulmonary manifestations of M. pneumoniae infection are rarely known to occur without pneumonia. Herein we report a case of a 9-year-old boy who presented with acute cholestatic hepatitis in the absence of pneumonia. Rhabdomyolysis, skin rash, and initial laboratory results suspicious of disseminated intravascular coagulopathy were also observed in this patient. M. pneumoniae infection was identified by a 4-fold increase in immunoglobulin G antibodies to M...
June 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28729262/genome-sequence-of-canine-polyomavirus-in-respiratory-secretions-of-dogs-with-pneumonia-of-unknown-etiology
#2
Eric Delwart, Beatrix Kapusinszky, Patricia A Pesavento, Marko Estrada, M Alexis Seguin, Christian M Leutenegger
We report here the first canine polyomavirus genome, identified by metagenomics in respiratory secretions of two dogs with severe pneumonia, which tested negative for all canine respiratory pathogens except Mycoplasma cynos The isolate, Canis familiaris polyomavirus 1 (DogPyV-1), is a beta polyomavirus whose closest known LT antigen relatives are primate polyomaviruses.
July 20, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28728317/mycoplasma-pneumoniae-associated-hepatitis-without-lung-involvement
#3
Han Taek Jeong, Jae Young Oh, Jung Eun Song, Byung Seok Kim, Chang Hyeong Lee
Mycoplasma pneumoniae (M. pneumoniae) is a major cause of community acquired respiratory infections. And it also causes a number of extrapulmonary manifestations including cardiovascular, dermatological, musculoskeletal, and hematological systems. But, acute hepatitis without lung involvement is rare in adults. Here, we report a case of 32-year-old man who presented with fever, chilling, myalgia, and headache. Biochemical analysis showed severely impaired liver function and leukopenia. Laboratory tests and liver biopsy demonstrated a hepatocellular pattern of M...
July 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28728264/-exploratory-research-on-diagnostic-essentials-of-pediatric-tuberculous-pleurisy
#4
H Xu, J R Liu, S Y Zhao
Objective: To summarize the clinical diagnostic essentials of pediatric tuberculous pleurisy so as to reduce the misdiagnosis rate. Method: A retrospective study was conducted on 113 cases of tuberculous pleurisy who were seen from August 2006 to September 2014 in the second Department of Respiratory Medicine, Beijing Children's Hospital Affiliated to Capital Medical University. Meanwhile, another 113 cases of children over 5 years of age with mycoplasma pneumoniae pneumonia complicated with pleural effusion were randomly selected as control group...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28726662/cytokines-as-the-predictors-of-severe-mycoplasma-pneumoniae-pneumonia-in-children-review
#5
I Chkhaidze, N Kapanadze
In spite of many attempts to differentiate bacterial from viral disease and predict severity and outcome, the etiologic diagnosis of paediatric community acquired pneumonia and the estimation of potential outcomes remain unsolved problems in most cases. Mycoplasma pneumoniae is one of the major pathogens causing CAP in children. Although MP infection was traditionally thought to be a self-limited process, more and more severe cases even fatal cases of MP infections were reported in recent years. So it is essential for pediatricians to recognize severe or refractory or severe MP early, treat it promptly and prevent the progress of the disease...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28725301/review-of-infectious-etiology-of-acute-pancreatitis
#6
REVIEW
Prashanth Rawla, Sathyajit S Bandaru, Anantha R Vellipuram
While gallstones and alcoholism are widely known to be the most common causative agents of acute pancreatitis, about 10% of cases are thought to be caused by infectious microorganisms. These microorganisms include viruses (e.g. mumps, Coxsackie B, and hepatitis), bacteria (e.g. Mycoplasma pneumoniae and leptospirosis), and parasites (e.g. Ascaris lumbricoides, Fasciola hepatica, and hydatid disease). Each organism causes acute pancreatitis through diverse mechanisms. The review is primarily conducted in an attempt to provide a better understanding of the possibility of acute pancreatitis presenting as a complication relating to these organisms, and the aim is to guide future diagnoses, management, and predictions of complications...
June 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28722366/-large-vessel-vasculitis-pathogenesis-diagnostic-and-medical-management
#7
Alireza Sadrkhah, Jörg D Seebach, Yannick Muller
Large vessels vasculitis includes two diseases : 1) giant cell arteritis, formerly known as Horton's arteritis and 2) Takayasu arteritis. In this article, we will describe and compare the epidemiology, pathogenesis, diagnostic criteria and medical management of both vasculitis. T helper (Th) 1 and Th17 responses, genetic links and the role of viral (varicella zoster) and bacterial infection (Mycoplasma pneumoniae or Chlamydia pneumoniae) will be discussed. Classification criteria, inflammation biomarkers and progress in imaging tools will also be described...
April 5, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28719637/microbiome-overview-in-swine-lungs
#8
Franciele Maboni Siqueira, Esteban Pérez-Wohlfeil, Fabíola Marques Carvalho, Oswaldo Trelles, Irene Silveira Schrank, Ana Tereza Ribeiro Vasconcelos, Arnaldo Zaha
Mycoplasma hyopneumoniae is the etiologic agent of swine enzootic pneumonia. However other mycoplasma species and secondary bacteria are found as inhabitants of the swine respiratory tract, which can be also related to disease. In the present study we have performed a total DNA metagenomic analysis from the lungs of pigs kept in a field condition, with suggestive signals of enzootic pneumonia and without any infection signals to evaluate the bacteria variability of the lungs microbiota. Libraries from metagenomic DNA were prepared and sequenced using total DNA shotgun metagenomic pyrosequencing...
2017: PloS One
https://www.readbyqxmd.com/read/28712517/comparison-of-oropharyngeal-and-nasopharyngeal-swab-specimens-for-the-detection-of-mycoplasma-pneumoniae-in-children-with-lower-respiratory-tract-infection
#9
Fujio Kakuya, Takahiro Kinebuchi, Hitoshi Okubo, Kumihiro Matsuo
The oropharyngeal swab specimen was superior to the nasopharyngeal swab specimen for the detection of Mycoplasma pneumoniae in children with lower respiratory tract infection. The oropharyngeal loop-mediated isothermal amplification had 100% sensitivity and specificity compared with polymerase chain reaction testing, whereas the oropharyngeal rapid antigen detection test using immunochromatographic assay had relatively low sensitivity (66%) and reasonable specificity (90.7%).
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28710842/severe-sequelae-of-erythema-multiforme-three-cases
#10
A Viarnaud, S Ingen-Housz-Oro, M Marque, L Valeyrie-Allanore, N Ortonne, J Gueudry, S Grootenboer-Mignot, M Muraine, E Bequignon, C Gagnière, F Schlemmer, P Wolkenstein, O Chosidow
Erythema multiforme (EM) is a skin condition for which main causes are infectious factors (Herpes simplex virus, Mycoplasma pneumoniae). Anti-plakin auto-antibodies are found in some patients (1) . EM must be distinguished from Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which are drug-induced in most cases (2-5) . This article is protected by copyright. All rights reserved.
July 14, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28700751/a-high-seroprevalence-of-antibodies-to-pertussis-toxin-among-japanese-adults-qualitative-and-quantitative-analyses
#11
Takumi Moriuchi, Nao Otsuka, Yukihiro Hiramatsu, Keigo Shibayama, Kazunari Kamachi
In 2013, national serosurveillance detected a high seroprevalence of antibodies to pertussis toxin (PT) from Bordetella pertussis among Japanese adults. Thus, we aimed to determine the cause(s) of this high seroprevalence, and analyzed the titers of antibodies to PT and filamentous hemagglutinin (FHA) among adults (35-44 years old), young children (4-7 years old), and older children (10-14 years old). Our quantitative analyses revealed that adults had higher seroprevalences of anti-PT IgG and PT-neutralizing antibodies, and similar titers of anti-FHA IgG, compared to the young and older children...
2017: PloS One
https://www.readbyqxmd.com/read/28697839/-effect-of-annexin-a2-on-egfr-nf-%C3%AE%C2%BAb-signal-transduction-and-mucin-expression-in-human-airway-epithelial-cells-treated-with-mycoplasma-pneumoniae
#12
Dong-Dong Shen, Fei Yuan, Jiang-Hong Hou
OBJECTIVE: To investigate the effect of annexin A2 (AnxA2) on epithelial growth factor receptor (EGFR)/nuclear factor-κB (NF-κB) signal transduction and mucin expression in human airway epithelial H292 cells treated with Mycoplasma pneumoniae (MP). METHODS: H292 cells were divided into control group, MP group, NC-siRNA+MP group, and AnxA2 siRNA+MP group. The cells in the MP group were incubated with 5 μg/mL MP antigen for 2 hours. The cells in the NC-siRNA+MP and AnxA2 siRNA+MP groups were transfected with NC-siRNA and AnxA2 siRNA for 24 hours, followed by MP antigen stimulation for 2 hours...
July 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28697827/-effects-of-huaiqihuang-granules-on-immune-function-in-children-with-severe-mycoplasma-pneumoniae-pneumonia
#13
Jin Liu, Hong Yan, Xiao-Geng Chen, Ya-Ping Mu
OBJECTIVE: To observe the effects of Huaiqihuang granules on the immune function in children with severe Mycoplasma pneumoniae pneumonia. METHODS: Pediatric inpatients with severe Mycoplasma pneumoniae pneumonia were randomly divided into Huaiqihuang granule treatment group (n=51) and conventional treatment group (n=47). The Huaiqihuang granule treatment group was orally administered Huaiqihuang granules in addition to the conventional treatment, while the conventional treatment group received conventional treatment only...
July 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28690643/mechanism-of-resistance-acquisition-and-treatment-of-macrolide-resistant-mycoplasma-pneumoniae-pneumonia-in-children
#14
REVIEW
Hyeon-Jong Yang, Dae Jin Song, Jung Yeon Shim
Mycoplasma pneumoniae pneumonia (MPP) is one of the most common forms of community-acquired pneumonia in children and adolescents. Outbreaks of MPP occur in 3- to 7-year cycles worldwide; recent epidemics in Korea occurred in 2006-2007, 2011, and 2015-2016. Although MPP is known to be a mild, self-limiting disease with a good response to macrolides, it can also progress into a severe and fulminant disease. Notably, since 2000, the prevalence of macrolide-resistant MPP has rapidly increased, especially in Asian countries, recently reaching up to 80%-90%...
June 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28688453/mycoplasma-pneumoniae-as-a-cause-of-vulvar-ulcers-in-a-non-sexually-active-girl-a-case-report
#15
Maria G Koliou, Talia Kakourou, Jan Richter, Christina Christodoulou, Elpidoforos S Soteriades
BACKGROUND: Non-sexually active young females very rarely develop genital ulcers. Such ulcers pose a diagnostic challenge as well as physical and emotional distress for patients and family; therefore, the search for their etiology requires exhaustive investigation. Several viruses such as Epstein-Barr virus have been associated with this entity; however, Mycoplasma pneumoniae has rarely been linked to such ulcers in the literature. We present a case of vulvar ulcers in a non-sexually active young girl during the course of pneumonia caused by Mycoplasma pneumoniae...
July 9, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28686393/-mycoplasma-pneumoniae-update-and-new-challenges
#16
Alexis Dumoulin
Mycoplasma pneumoniae is a frequent cause of community acquired pneumonia, especially in children. Discovered by Eaton in the 1940s, it has long been considered as a virus, in part because of its difficult growth in cultures. M. pneumoniae can cause many complications, some of which are severe such as dermatological lesions or affections of the central nervous system. The laboratory diagnosis of M. pneumoniae is difficult, notably because of the fastidious growth conditions, the persistence of IgM antibody after acute infection and the debated existence of asymptomatic carriers...
October 12, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28683450/acute-kidney-injury-and-hemolytic-anemia-secondary-to-mycoplasma-pneumoniae-infection
#17
Camillo Carrara, Mauro Abbate, Ettore Sabadini, Giuseppe Remuzzi
Glomerulonephritis as well as kidney injury secondary to fulminant intravascular hemolysis are rare extrapulmonary manifestations of Mycoplasma pneumoniae infection. We describe a 50-year-old female diagnosed with M. pneumoniae infection-associated hemolytic anemia, characterized by negative cold agglutinin tests but with laboratory evidence of complement alternative pathway activation. The patient presented both with anemia and severe kidney failure and she was treated with steroids and red blood cell transfusions along with plasmapheresis...
July 7, 2017: Nephron
https://www.readbyqxmd.com/read/28672017/the-association-between-mycoplasma-pneumoniae-infection-and-speech-and-language-impairment-a-nationwide-population-based-study-in-taiwan
#18
Ching-Shu Tsai, Vincent Chin-Hung Chen, Yao-Hsu Yang, Tai-Hsin Hung, Mong-Liang Lu, Kuo-You Huang, Michael Gossop
Manifestations of Mycoplasma pneumoniae infection can range from self-limiting upper respiratory symptoms to various neurological complications, including speech and language impairment. But an association between Mycoplasma pneumoniae infection and speech and language impairment has not been sufficiently explored. In this study, we aim to investigate the association between Mycoplasma pneumoniae infection and subsequent speech and language impairment in a nationwide population-based sample using Taiwan's National Health Insurance Research Database...
2017: PloS One
https://www.readbyqxmd.com/read/28671088/correlation-study-of-cough-variant-asthma-and-mycoplasma-pneumonia-infection-in-children
#19
Wen Li, Cunfang Ban, Junxia Zhang, Yingying Hu, Bingjuan Han, Bingchao Han
Cough variant asthma (CVA), as one of bronchitis diseases, features with repeated cough. In clinics, CAV does not show significant abnormal signs, therefore antibiotic therapy can hardly achieve satisfactory treatment effect. With the development of scientific technologies, the correlation between mycoplasma pneumoniae infection and CVA has become a hot research topic in clinics. In clinics, mycoplasma pneumoniae is extensively regarded as major cause for CVA, with complex pathogenic mechanism. The symptoms of CVA is characterized by chronic non abnormal inflammation, normally accompanied with bronchospasm and intestinal infection...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28668570/changes-in-pathogens-and-pneumococcal-serotypes-causing-community-acquired-pneumonia-in-the-netherlands
#20
Stefan M T Vestjens, Gertjan H J Wagenvoort, Jan C Grutters, Bob Meek, Arnoud F Aldenkamp, Bart J M Vlaminckx, Willem-Jan W Bos, Ger T Rijkers, Ewoudt M W van de Garde
BACKGROUND: In 2006 a 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the immunisation programme for infants in The Netherlands and replaced by PCV10 in 2011. Limited data exist about the impact of PCV on the aetiology of CAP as a whole. The aim of the present study is to describe the overall changes in microbial aetiology, pneumococcal burden (including non-bacteraemic pneumococcal pneumonia) and its serotypes in adult community-acquired pneumonia (CAP) after the introduction of these PCVs...
June 28, 2017: Vaccine
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