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mycoplasma pneumoniae

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https://www.readbyqxmd.com/read/29232879/the-alteration-of-nasopharyngeal-and-oropharyngeal-microbiota-in-children-with-mpp-and-non-mpp
#1
Zhiwei Lu, Wenkui Dai, Yanhong Liu, Qian Zhou, Heping Wang, Dongfang Li, Zhenyu Yang, Yinhu Li, Gan Xie, Shuaicheng Li, Yuejie Zheng
Background: In recent years, the morbidity of Mycoplasma pneumoniae pneumonia (MPP) has increased significantly in China. A growing number of studies indicate that imbalanced respiratory microbiota is associated with various respiratory diseases. Methods: We enrolled 119 children, including 60 pneumonia patients and 59 healthy children. Nasopharyngeal (NP) and oropharyngeal (OP) sampling was performed for 16S ribosomal RNA (16S rRNA) gene analysis of all children. Sputum and OP swabs were obtained from patients for pathogen detection...
December 11, 2017: Genes
https://www.readbyqxmd.com/read/29232459/definitive-diagnosis-in-suspected-middle-east-respiratory-syndrome-coronavirus-cases
#2
Elisa Rubio, Miguel J Martínez, Verónica Gonzalo, Josep Barrachina, Núria Torner, Ana I Martínez, Mireia Jané, Anna Vilella, Ana Del Rio, Natalia Rodriguez-Valero, Maria Jesús Pinazo, José Muñoz, Alex Soriano, Antoni Trilla, Jordi Vila, Ma Ángeles Marcos
We evaluated the microbiological diagnosis in 14 patients with epidemiological and clinical suspicion of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) attended in a non-endemic area between June 2015 and January 2017. While no MERS-CoV was detected, other respiratory viruses were identified in 12 cases and Mycoplasma pneumoniae in 1 case.
January 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29229084/serological-study-of-bordetella-pertussis-mycoplasma-pneumonia-and-chlamydia-pneumonia-in-iranian-hajj-pilgrims-with-prolonged-cough-illnesses-a-follow-up-study
#3
Masoud Rahimian, Mahdi HosseiniB
INTRODUCTION: Hajj pilgrimage is the biggest and longest mass gathering in the Muslim world. Annually, about 50% of more than 2.5 million pilgrims participating in this ritual get involved in severe devastating coughs. Most coughs continue, so the pilgrims turn back home and transmit them to family members and other people. Despite the high prevalence of coughs for many years, what causes them remains unknown. Considering the pertussis-like clinical picture of the so-called "hajj coughs", the researchers conducted a study to measure antibodies against three known common atypical bacteria, namely Bordetella Pertussis, Chlamydia Pneumonia and Mycoplasma Pneumonia...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29224300/-etiological-analysis-and-establishment-of-a-discriminant-model-for-lower-respiratory-tract-infections-in-hospitalized-patients
#4
Y S Chen, X H Lin, H R Li, Z D Hua, M Q Lin, W S Huang, T Yu, H Y Lyu, W P Mao, Y Q Liang, X R Peng, S J Chen, H Zheng, S Q Lian, X L Hu, X Q Yao
Objective: To analyze the pathogens of lower respiratory tract infection(LRTI) including bacterial, viral and mixed infection, and to establish a discriminant model based on clinical features in order to predict the pathogens. Methods: A total of 243 hospitalized patients with lower respiratory tract infections were enrolled in Fujian Provincial Hospital from April 2012 to September 2015. The clinical data and airway (sputum and/or bronchoalveolar lavage) samples were collected. Microbes were identified by traditional culture (for bacteria), loop-mediated isothermal amplification(LAMP) and gene sequencing (for bacteria and atypical pathogen), or Real-time quantitative polymerase chain reaction (Real-time PCR)for viruses...
December 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29221755/unilateral-brachial-plexopathy-a-rare-complication-of-mycoplasma-pneumoniae-infection
#5
Barbara Robnik, Darja Keše, Tereza Rojko, Alenka Horvat-Ledinek, Aleš Pražnikar, Bojana Beović
Few reports in the literature describe isolated peripheral neuropathies in relation to Mycoplasma pneumoniae infection without concurrent damage to the central nervous system. To our knowledge only a single case of mononeuritis multiplex with brachial plexus neuropathy coincident with M. pneumoniae has been documented until now. Here we present the first clinical case of lobar M. pneumoniae pneumonia in a 19-year-old female patient, where coincident neurological complications manifested as unilateral brachial plexus neuropathy, affecting axillar and suprascapular nerves...
December 5, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29212701/multicenter-evaluation-of-the-eplex%C3%A2-respiratory-pathogen-panel-for-the-detection-of-viral-and-bacterial-respiratory-tract-pathogens-in-nasopharyngeal-swabs
#6
N Esther Babady, Matthew R England, Kristen L Jurcic Smith, Taojun He, Dona Saumya Wijetunge, Yi-Wei Tang, Robin R Chamberland, Marilyn Menegus, Ella M Swierkosz, Robert C Jerris, Wallace Greene
Background: The performance of the new ePlex® Respiratory Pathogen (RP) Panel (GenMark Diagnostics) for the simultaneous detection of 19 viruses (influenza A, influenza A H1, influenza A 2009 H1, influenza A H3, influenza B, adenovirus, coronaviruses [HKU1, OC43, NL63, 229E], human rhinovirus/enterovirus, human metapneumovirus, parainfluenza viruses 1, 2, 3 and 4, respiratory syncytial virus (RSV) [RSVA and RSV B]) and two bacteria (Mycoplasma pneumoniae and Chlamydia pneumoniae) was evaluated.Methods: Prospectively and retrospectively collected nasopharyngeal swab (NPS) specimens (n =2,908) were evaluated using the ePlex RP Panel with the bioMérieux/BioFire FilmArray® Respiratory Panel (BF RP) as the comparator method...
December 6, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29212389/antimicrobial-therapy-of-macrolide-resistant-mycoplasma-pneumoniae-pneumonia-in-children
#7
Hyunju Lee, Ki Wook Yun, Hoan Jong Lee, Eun Hwa Choi
Mycoplasma pneumoniae is an important cause of community-acquired pneumonia in children and young adolescents. Macrolides are recommended as the first-line therapy however, macrolide resistance rates in M. pneumoniae among children have been increasing substantially. Areas covered: This review focused on clinical characteristics and treatment of macrolide-resistant M. pneumoniae pneumonia in children. Expert commentary: Antibiotic choice should be based on in vitro activity, clinical efficacy and in consideration of potential adverse events...
December 7, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29208015/molecular-etiological-profile-of-atypical-bacterial-pathogens-viruses-and-coinfections-among-infants-and-children-with-community-acquired-pneumonia-admitted-to-a-national-hospital-in-lima-peru
#8
Juana Del Valle-Mendoza, Wilmer Silva-Caso, Angela Cornejo-Tapia, Fiorella Orellana-Peralta, Eduardo Verne, Claudia Ugarte, Miguel Angel Aguilar-Luis, María Del Carmen De Lama-Odría, Ronald Nazario-Fuertes, Mónica Esquivel-Vizcarra, Verónica Casabona-Ore, Pablo Weilg, Luis J Del Valle
OBJECTIVE: The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via polymerase chain reaction in patients under 18 years old hospitalized due to community-acquired pneumonia (CAP) from Lima, Peru. RESULTS: Atypical pathogens were detected in 40% (58/146); viral etiologies in 36% (52/146) and coinfections in 19% (27/146). The most common etiological agent was M...
December 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29207801/autoimmune-haemolytic-anaemia-a-spectrum-of-presentation-in-children
#9
Amitabh Singh, Anirban Mandal, Ankita Patel, Sataroopa Mishra
Autoimmune Haemolytic Anaemias (AIHAs) are rare in children. They can be either a primary disease or secondary to/triggered by a host of other clinical conditions. We present five interesting cases of paediatric AIHA associated with infections (viral, bacterial and atypical) and autoimmune diseases {Systemic Lupus Erythematosus (SLE) and Autoimmune Hepatitis (AIH)}. The H1N1 influenza associated AIHA responded to oseltamivir and Intravenous Immunoglobulin (IvIg) while the cases secondary to Mycoplasma pneumoniae and pneumococcal bacteraemia required only treatment of the primary infection...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29192604/leukoagglutination-mycoplasma-pneumoniae-pneumonia-and-edta-blood
#10
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
December 1, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/29184760/rhabdomyolysis-with-different-etiologies-in-childhood
#11
Demet Alaygut, Meral Torun Bayram, Belde Kasap, Alper Soylu, Mehmet Türkmen, Salih Kavukcu
AIM: To investigate different etiologies and management of the rhabdomyolysis in children. METHODS: Eight pediatric rhabdomyolysis cases who applied to the Dokuz Eylul University Faculty of Medicine Department of Pediatric Nephrology with different etiologies between January 2004 and January 2012 were evaluated in terms of age, gender, admission symptoms, physical examination findings, factors provoking rhabdomyolysis, number of rhabdomyolysis attacks, laboratory results, family history and the final diagnosis received after the treatment...
November 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/29181207/mycoplasma-pneumonia-an-unrecognized-cause-of-fever-of-unknown-origin-in-an-adult
#12
Fatima Ali-Ahmed, Alexandra Halalau
A 26-year-old female was admitted for fever of unknown origin (FUO), headaches, left ankle edema, and a lower extremity rash consistent with erythema nodosum. She had no respiratory symptoms or family history of autoimmune diseases. A chest X-ray was negative for pneumonia or hilar adenopathy. Extensive autoimmune workup was negative. A chest, abdomen, and pelvis computed tomography scan was unremarkable and laboratory studies revealed no source of infection. On hospital day 5, the patient developed a mild productive cough...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29180641/a-sensitive-and-rapid-immunoassay-for-mycoplasma-pneumoniae-in-children-with-pneumonia-based-on-single-walled-carbon-nanotubes
#13
Ming Song, Ying Zhang, Shi Li, Chunsheng Zhang, Mingming Tao, Ying Tang, Zhuquan Jiang, Sulan Cai, Wei Xu, Weizhuo Xu
Mycoplasma pneumoniae(MP) is a leading pathogen of respiratory infection, especially community-acquired pneumonia (CAP), in children worldwide. However, its diagnosis is frequently ineffective because bacterial culture and serology test are usually positive 1-2 weeks or more after the disease onset. To achieve a better detection efficiency, the single-walled carbon nanotubes(SWCNT) were coupled with the colloidal gold-monoclonal antibody immunochromatographic strips(CGIC). Interestingly, the SWCNT/CGIC assay allowed MP identification, with a detection limit of 1 × 102 copies/ml...
November 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29173125/time-series-analysis-variation-of-anti-acetylcholine-receptor-antibody-titer-in-myasthenia-gravis-is-related-to-incidence-of-mycoplasma-pneumoniae-and-influenza-virus-infections
#14
Kazuo Iwasa, Hiroaki Yoshikawa, Tsuyoshi Hamaguchi, Kenji Sakai, Moeko Shinohara-Noguchi, Miharu Samuraki, Kazuya Takahashi, Daisuke Yanase, Kenjiro Ono, Chiho Ishida, Mitsuhiro Yoshita, Hiroyuki Nakamura, Masahito Yamada
Objectives The exacerbating factors of myasthenia gravis (MG) are unknown. However, it has been speculated that infections may play a role in disease progression. Methods We calculated the adjusted anti-acetylcholine receptor antibody (Adj-AChR-Ab) titers (range, 0-1) in 58 MG patients between 2006 and 2012. We determined the relationship between Adj-AChR-Ab titer and infection incidence. Results A cross-correlation function (CCF) analysis of Adj-AChR-Ab titer and incidence of Mycoplasma pneumoniae (M. pneumoniae) (r = 0...
November 24, 2017: Neurological Research
https://www.readbyqxmd.com/read/29155483/modeling-persistent-mycoplasma-pneumoniae-infection-of-human-airway-epithelium
#15
Oliver A Prince, Thomas M Krunkosky, Edward S Sheppard, Duncan C Krause
Mycoplasma pneumoniae is a human respiratory tract pathogen causing acute and chronic airway disease states that can include long-term carriage and extra-pulmonary spread. The mechanisms of persistence and migration beyond the conducting airways, however, remain poorly understood. We previously described an acute exposure model using normal human bronchial epithelium (NHBE) in air-liquid interface culture, showing that M. pneumoniae gliding motility is essential for initial colonization and subsequent spread, including localization to epithelial cell junctions...
November 20, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/29155089/genotyping-and-macrolide-resistance-of-mycoplasma-pneumoniae-identified-in-children-with-community-acquired-pneumonia-cap-in-medellin-colombia
#16
Angela Rocio Copete, Yudy Alexandra Aguilar, Zulma Vanessa Rueda, Lázaro Agustín Vélez
OBJECTIVES: Our aim was to describe the genotypes and the main characteristics of the CAP cases caused by M. pneumoniae in hospitalized children in Medellin and in neighboring municipalities in 2011-2012. METHODOLOGY: The M. pneumoniae genotype was determined by PCR and sequencing of the p1 and 23S rRNA genes from induced sputum samples and nasopharyngeal swabs (NPS) from children with CAP who were hospitalized in 13 healthcare centers. In addition, a spatio-temporal analysis was performed to identify the potential risk areas and clustering of the cases over time...
November 15, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29152324/a-field-efficacy-and-safety-trial-in-the-netherlands-in-pigs-vaccinated-at-3%C3%A2-weeks-of-age-with-a-ready-to-use-porcine-circovirus-type-2-and-mycoplasma-hyopneumoniae-combined-vaccine
#17
Luuk Kaalberg, Victor Geurts, Rika Jolie
Background: Respiratory diseases impair the health and welfare of growing pigs and impacts farmers' gains worldwide. Their control through a preventative medical approach has to be tailored according to the pathogens identified at farm level. In the Netherlands, several studies have emphasized the prominent role of Mycoplasma hyopneumoniae, Porcine Circovirus type 2 and Porcine Reproductive and Respiratory Syndrome Virus in such respiratory conditions. Further to the arrival on the Dutch market of the first commercially available bivalent vaccine against PCV2 and M...
2017: Porcine Health Management
https://www.readbyqxmd.com/read/29152280/mycoplasma-pneumoniae-associated-encephalitis-complicated-by-cerebral-salt-wasting-syndrome
#18
Ya-Lan Lin, Kun-Long Hung, Chiao-Wei Lo
Cerebral salt wasting syndrome can occur in children with encephalitis. Clinicians should be aware of hyponatremia in patients who develop polyuria with the signs of dehydration and deteriorated consciousness. Furthermore, patients who present with status epilepticus or who are suspected to have high intracranial pressure may have an increased risk of cerebral salt wasting syndrome.
November 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29139241/porcine-respiratory-disease-complex-after-the-introduction-of-h1n1-2009-influenza-virus-in-brazil
#19
R R Rech, D Gava, M C Silva, L T Fernandes, V Haach, J R Ciacci-Zanella, R Schaefer
From 2009 to 2015, 74 lungs from suckling (6.8%), nursing (70.3%), fattening (20.3%) pigs and pregnant sows (2.7%) with respiratory signs from pig farms in Southern Brazil were submitted to a diagnostic laboratory for necropsy and/or histologic examination and screening for respiratory agents by RT-qPCR, immunohistochemistry (IHC), virus isolation (VI) and subtyping for influenza A virus (IAV), IHC and nested PCR for Mycoplasma hyopneumoniae (Mhyo), PCR for porcine circovirus 2 (PCV2), RT-qPCR for porcine reproductive and respiratory syndrome virus (PRRSV) and bacterial culture...
November 14, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29137804/corrigendum-to-a-novel-detection-procedure-for-mutations-in-the-23s-rrna-gene-of-mycoplasma-pneumoniae-with-peptide-nucleic-acid-mediated-loop-mediated-isothermal-amplification-assay-j-microbiol-methods-141-2017-90-96
#20
Jun Sakai, Takuya Maeda, Norihito Tarumoto, Kazuhisa Misawa, Shinsuke Tamura, Kazuo Imai, Toshiyuki Yamaguchi, Satoshi Iwata, Takashi Murakami, Shigefumi Maesaki
No abstract text is available yet for this article.
November 11, 2017: Journal of Microbiological Methods
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