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mycoplasma pneumoniae

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https://www.readbyqxmd.com/read/28228838/a-rare-case-of-bilateral-optic-neuritis-and-guillain-barr%C3%A3-syndrome-post-mycoplasma-pneumoniae-infection
#1
Aravindhan Baheerathan, Amy Ross Russell, Fion Bremner, Simon F Farmer
Neurological complications are the most commonly encountered extra-pulmonary manifestation of infection with Mycoplasma pneumoniae (M. pneumoniae). Here the authors report the case of a 39-year-old woman who was admitted with acute-onset bilateral visual loss coinciding with ascending numbness. Clinical examination, neurological imaging, and nerve conduction studies revealed a syndrome of bilateral optic neuritis and Guillain-Barré syndrome (GBS). Serological testing confirmed recent exposure to M. pneumoniae...
February 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/28217905/evaluation-of-rv0220-rv2958c-rv2994-and-rv3347c-of-mycobacterium-tuberculosis-for-serodiagnosis-of-tuberculosis
#2
Xiaolong You, Ranhui Li, Kanglin Wan, Liangzhuan Liu, Xiaoping Xie, Lanhua Zhao, Ning Wu, Xiangying Deng, Li Wang, Yanhua Zeng
Tuberculosis (TB), the leading cause of death among infectious diseases worldwide, is caused by Mycobacterium tuberculosis (M. tuberculosis). Early accurate diagnosis means earlier prevention, treatment and control of TB. To confirm efficient diagnostic antigens for M. tuberculosis, the serodiagnosis value of four recombinant proteins including Rv0220, Rv2958c, Rv2994 and Rv3347c was evaluated in this study. The specificities and sensitivities of four recombinant proteins were determined based on enzyme-linked immunosorbent assay (ELISA) by screening sera from smear-positive pulmonary TB patients (n = 92), uninfected individuals (n = 60) and patients with Mycoplasma pneumoniae (n = 32) that potentially cross-react with M...
February 20, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28204467/the-surface-displayed-chaperones-groel-and-dnak-of-mycoplasma-pneumoniae-interact-with-human-plasminogen-and-components-of-the-extracellular-matrix
#3
Lisa Hagemann, Anne Gründel, Enno Jacobs, Roger Dumke
No abstract text is available yet for this article.
February 15, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28199385/mycoplasma-pneumoniae-cards-toxin-elicits-a-functional-ige-response-in-balb-c-mice
#4
Jorge L Medina, Edward G Brooks, Adriana Chaparro, Peter H Dube
Mycoplasma pneumoniae is strongly associated with new onset asthma and asthma exacerbations. Until recently, the molecular mechanisms utilized by M. pneumoniae to influence asthma symptoms were unknown. However, we recently reported that an ADP-ribosylating and vacuolating toxin called the Community Acquired Respiratory Distress Syndrome toxin, CARDS toxin, produced by M. pneumoniae was sufficient to promote allergic inflammation and asthma-like disease in mice. A mouse model of CARDS toxin exposure was used to evaluate total and CARDS-toxin specific serum IgE responses...
2017: PloS One
https://www.readbyqxmd.com/read/28198756/utility-of-assessing-cytokine-levels-for-the-differential-diagnosis-of-pneumonia-in-a-pediatric-population
#5
Jian-Ming Zhou, Qing Ye
OBJECTIVES: Although pneumonia is easily diagnosed, determining the causative agent is difficult due to low pathogen detection rates. We performed a prospective observational study to evaluate the utility of measuring inflammatory cytokine levels to discriminate between pneumonia caused by typical bacteria, respiratory syncytial virus, or Mycoplasma pneumoniae in a pediatric population. DESIGN: Serum inflammatory cytokine levels at early stages of the disease were evaluated for pneumonia caused by the three different pathogenic microorganisms...
February 14, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28194450/assessment-of-the-adjuvant-activity-of-mesoporous-silica-nanoparticles-in-recombinant-mycoplasma-hyopneumoniae-antigen-vaccines
#6
Veridiana Gomes Virginio, Natalia Costantin Bandeira, Fernanda Munhoz Dos Anjos Leal, Marcelo Lancellotti, Arnaldo Zaha, Henrique Bunselmeyer Ferreira
The adjuvant potential of two mesoporous silica nanoparticles (MSNs), SBa-15 and SBa-16, was assessed in combination with a recombinant HSP70 surface polypeptide domain from Mycoplasma hyopneumoniae, the etiological agent of porcine enzootic pneumonia (PEP). The recombinant antigen (HSP70212-600), previously shown as immunogenic in formulation with classic adjuvants, was used to immunize BALB/c mice in combination with SBa-15 or SBa-16 MSNs, and the effects obtained with these formulations were compared to those obtained with alum, the adjuvant traditionally used in anti-PEP bacterins...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28192042/assessing-timing-and-causes-of-neonatal-lamb-losses-in-a-bighorn-sheep-ovis-canadensis-canadensis-herd-via-use-of-vaginal-implant-transmitters
#7
Jamin L Grigg, Lisa L Wolfe, Karen A Fox, Halcyon J Killion, Jessica Jennings-Gaines, Michael W Miller, Brian P Dreher
We evaluated the use of vaginal implant transmitters (VITs) as a means of detecting, capturing, and radio collaring Rocky Mountain bighorn sheep ( Ovis canadensis canadensis) lambs to estimate survival and to facilitate carcass recovery to assess causes of mortality. We focused on one of several bighorn herds in Colorado, USA, suffering from depressed recruitment that was not preceded by a classic all-age die-off. We captured, radio-collared, diagnosed pregnancy by ultrasound examination, and inserted VITs into 15 pregnant ewes from a herd residing near Granite, Colorado...
February 13, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28187063/prevalence-of-mycoplasma-pneumoniae-infection-in-malagasy-children
#8
Ravelomanana Lova, Bouazza Naim, Mbola Rakotomahefa, André Zo Andrianirina, Annick Lalaina Robinson, Honoré Raobidjaona, Rabezanahary Andriamihaja, Nadjet Benhaddou, Fréderique Randrianirina, Elisoa Ratsima, Patrick Imbert, Josette Raymond
BACKGROUND: Childhood community acquired pneumonia (CAP) is a leading cause of childhood morbidity in low-income countries. The etiologic agents are usually Staphylococcus aureus, Streptococcus pneumoniae and Mycoplasma pneumoniae. M. pneumoniae was recognized as co-factor in asthmatic disease. High asthma prevalence was reported in Madagascar. Our aim was to clarify the prevalence of M. pneumoniae infection in this country and its relationship with asthma. METHODS: A prospective study was conducted in 351 children (aged from 2 to 16 years) from January 2012 to December 2014...
February 9, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28182741/etiology-of-severe-pneumonia-in-ecuadorian-children
#9
Sivani Jonnalagadda, Oswaldo Rodríguez, Bertha Estrella, Lora L Sabin, Fernando Sempértegui, Davidson H Hamer
BACKGROUND: In Latin America, community-acquired pneumonia remains a major cause of morbidity and mortality among children. Few studies have examined the etiology of pneumonia in Ecuador. METHODS: This observational study was part of a randomized, double blind, placebo-controlled clinical trial conducted among children aged 2-59 months with severe pneumonia in Quito, Ecuador. Nasopharyngeal and blood samples were tested for bacterial and viral etiology by polymerase chain reaction...
2017: PloS One
https://www.readbyqxmd.com/read/28178776/diagnosis-and-treatment-of-mycoplasma-pneumoniae-in-children
#10
Lindsay E Rogozinski, Brian K Alverson, Eric A Biondi
Mycoplasma pneumoniae is a common cause of community-acquired respiratory tract infections and accounts for up to 40% of cases of pneumonia in children over age 5. This article seeks to provide a general overview of the current recommended management of Mycoplasma pneumoniae infection in children.
April 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28159161/atypical-pneumonia-updates-on-legionella-chlamydophila-and-mycoplasma-pneumonia
#11
REVIEW
Lokesh Sharma, Ashley Losier, Thomas Tolbert, Charles S Dela Cruz, Chad R Marion
Community-acquired pneumonia (CAP) has multiple causes and is associated with illness that requires admission to the hospital and mortality. The causes of atypical CAP include Legionella species, Chlamydophila, and Mycoplasma. Atypical CAP remains a diagnostic challenge and, therefore, likely is undertreated. This article reviews the advancements in the evaluation and treatment of patients and discusses current conflicts and controversies of atypical CAP.
March 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/28159158/diagnosing-viral-and-atypical-pathogens-in-the-setting-of-community-acquired-pneumonia
#12
REVIEW
Grant W Waterer
The 'atypical' pathogens causing pneumonia have long been problematic for physicians because we have had to rely on serologic tests to make a diagnosis. The introduction of polymerase chain reaction techniques revolutionized the diagnosis of respiratory infections and now a new wave of technologies promising faster, cheaper, and more comprehensive testing are becoming available. This review focuses principally on the diagnosis of Legionella, Mycoplasma, and influenza infections, but also covers recent publications on the cutting edge of diagnostic tools likely to transform the field of infectious diseases over the coming decade...
March 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/28155329/pattern-and-significance-of-asymptomatic-elevation-of-liver-enzymes-in-mycoplasma-pneumonia-in-children
#13
Deepti Jujaray, Liu Zheng Juan, Shraddha Shrestha, Ashiana Ballgobin
Mycoplasma infection is on the rise in recent times. It usually infects any system, including liver. This study aims to show the significance of elevated liver enzymes in mycoplasma pneumonia and to have a look at future prospects. This is a single-center retrospective study involving 105 children serologically positive for mycoplasma IgM and IgG antibodies and 50 with community-acquired pneumonia caused by organisms other than mycoplasma and Epstein-Barr virus from June 2015 to June 2016 and all without prior liver disease...
January 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28144069/a-severe-mycoplasma-pneumoniae-pneumonia-inducing-an-acute-antibody-mediated-pulmonary-graft-rejection
#14
Sarah Démir, Julien Saison, Agathe Sénéchal, Jean-Francois Mornex
A 40-year-old cystic fibrosis woman with a history of double-lung transplantation 2 years previously was admitted for a progressive respiratory distress. Physical examination revealed fever (39°C) and diffuse bilateral lung crackles. Laboratory findings included severe hypoxemia and inflammatory syndrome. Bronchoalveolar lavage and serological test were positive for mycoplasma pneumonia. As the patient did not improve after 3 days of antibiotics and donor-specific HLA antibodies had been detected, an acute antibody-mediated graft rejection was treated with high-dose corticosteroids, plasma exchange, intravenous immunoglobulin, and rituximab...
January 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28139879/differences-in-inflammatory-marker-patterns-for-adult-community-acquired-pneumonia-patients-induced-by-different-pathogens
#15
Meng Liu, Hui Li, Chun Xue Xue, Li Gu, Jiu Xin Qu, Yi Min Wang, Ying Mei Liu, Bin Cao, Meng Liu, Hui Li, Chun Xue Xue, Li Gu, Jiu Xin Qu, Yi Min Wang, Ying Mei Liu, Bin Cao
INTRODUCTION: The inflammatory marker patterns of Community-acquired Pneumonia (CAP) induced by different microorganisms in adult patients remained unclear. OBJECTIVES: We aim to explore the inflammatory marker patterns of adult CAP patients induced by different pathogens. METHODS: Adult CAP patients with definite etiologies were enrolled from September 2010 to June 2012. They were divided into three groups according to the causative pathogens: typical bacteria, Mycoplasma pneumoniae (MP), and viruses...
January 31, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28130749/effects-of-methylprednisolone-or-immunoglobulin-when-added-to-standard-treatment-with-intravenous-azithromycin-for-refractory-mycoplasma-pneumoniae-pneumonia-in-children
#16
Li-Shen Shan, Xin Liu, Xin-Yuan Kang, Fei Wang, Xiao-Hua Han, Yun-Xiao Shang
BACKGROUND: The prevalence of Mycoplasma pneumoniae pneumonia has increased considerably in recent years. To evaluate the effi cacy of combined treatment of azithromycin with intravenous immunoglo-bulin (IVIG) or methylprednisolone in children with refractory Mycoplasma pneumoniae pneumonia (RMPP). METHODS: Children with RMPP were randomly allocated to group A [intravenous azithromycin (IA)+ methylprednisolone], group B (IA+IVIG) or group C (IA alone). Following a 7-day treatment, group C patients were randomly separated into two sub-groups: group C1 (IA+methylprednisolone) and group C2 (IA+IVIG)...
January 27, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28129377/high-prevalence-of-mycoplasma-pneumoniae-and-chlamydia-pneumoniae-in-children-with-acute-respiratory-infections-from-lima-peru
#17
Juana Del Valle-Mendoza, Fiorella Orellana-Peralta, Alvaro Marcelo-Rodríguez, Eduardo Verne, Mónica Esquivel-Vizcarra, Wilmer Silva-Caso, Miguel Angel Aguilar-Luis, Pablo Weilg, Verónica Casabona-Oré, Claudia Ugarte, Luis J Del Valle
BACKGROUND: Mycoplasma pneumoniae and Chlamydia pneumoniae are atypical pathogens responsible for pneumonia and a leading cause of morbidity and mortality in low income countries. The study objective is to determine the prevalence of this pathogens in Peruvian children with acute respiratory infections. METHODS: A consecutive cross-sectional study was conducted in Lima, Peru from May 2009 to September 2010. A total of 675 children admitted with clinical diagnoses of acute respiratory infections were tested for Mycoplasma pneumoniae and Chlamydia pneumoniae detection by polymerase chain reaction (PCR), and clinical symptoms were registered by the attending physician...
2017: PloS One
https://www.readbyqxmd.com/read/28124966/-a-case-of-bronchiolitis-obliterans-secondary-to-human-metapneumovirus-bronchiolitis
#18
Osman Yeşilbaş, Esra Şevketoğlu, Hasan Serdar Kıhtır, Mey Talip Petmezci, Elif Bato, Seda Balkaya, Nevin Hatipoğlu, Mert Ahmet Kuşkucu, Figen Palabıyık, Erkan Çakır
Human metapneumovirus (hMPV), formerly classified in Paramyxoviridae family is now moved into Pneumoviridae, which was described as a novel family. It causes upper and lower respiratory tract infections (LRTIs) usually in children younger than five years old. The recent epidemiological studies indicated that hMPV is the second most frequently detected virus in LRTIs of young children, following the respiratory syncytial virus (RSV). Bronchiolitis obliterans (BO) is a chronic obstructive lung disease characterized by fibrosis of the distal respiratory airways...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28121925/prospective-etiological-investigation-of-community-acquired-pulmonary-infections-in-hospitalized-people-living-with-hiv
#19
Claudia Figueiredo-Mello, Pontus Naucler, Marinella D Negra, Anna S Levin
The study of the etiological agents of community-acquired pulmonary infections is important to guide empirical therapy, requires constant updating, and has a substantial impact on the prognosis of patients. The objective of this study is to determine prospectively the etiology of community-acquired pulmonary infections in hospitalized adults living with HIV. Patients were submitted to an extended microbiological investigation that included molecular methods. The microbiological findings were evaluated according to severity of the disease and pneumococcal vaccine status...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28119816/acute-respiratory-distress-syndrome-related-to-mycoplasma-pneumoniae-infection
#20
Nouha Chaabane, Elisabeth Coupez, Matthieu Buscot, Bertrand Souweine
M. pneumoniae respiratory infection is usually mild and self-limiting. We report a case of acute respiratory distress syndrome (ARDS) due to M. pneumoniae infection in a 60 years old woman. Quick diagnosis was established by multiplex PCR assay for detection of pneumonia-causing bacteria. Outcome was favorable. The factors accounting for the severity of pneumonia caused by M. pneumoniae are discussed.
2017: Respiratory Medicine Case Reports
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