keyword
MENU ▼
Read by QxMD icon Read
search

pneumoniae

keyword
https://www.readbyqxmd.com/read/28944408/etiology-of-childhood-pneumonia-what-we-know-and-what-we-need-to-know-based-on-5th-dr-ic-verma-excellence-oration-award
#1
Joseph L Mathew
Childhood community acquired pneumonia continues to be an important clinical problem at the individual, institutional and community levels. Determination of microbial etiology is critical to develop evidence-based management (therapeutic and prophylactic) decisions. For decades, the approach to this relied on culture of lung aspirate specimens obtained from children with radiographically confirmed pneumonia, before administering antibiotics. Such studies revealed the major bacteria associated with pneumonia, prompting the World Health Organization to develop a highly sensitive clinical definition of pneumonia and advocate empiric antibiotic therapy; in order to save lives (focusing on community settings lacking resources for diagnostic tests)...
September 25, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28944216/legionella-effector-ankx-disrupts-host-cell-endocytic-recycling-in-a-phosphocholination-dependent-manner
#2
Samual C Allgood, Barbara P Romero Dueñas, Rebecca R Noll, Colleen Pike, Sean Lein, M Ramona Neunuebel
The facultative intracellular bacterium Legionella pneumophila proliferates within amoebae and human alveolar macrophages, and it is the causative agent of Legionnaires' disease, a life-threatening pneumonia. Within host cells, L. pneumophila establishes a replicative haven by delivering numerous effector proteins into the host cytosol, many of which target membrane trafficking by manipulating the function of Rab GTPases. The Legionella effector AnkX is a phosphocholine transferase that covalently modifies host Rab1 and Rab35...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28943583/invasive-liver-abscess-syndrome-caused-by-klebsiella-pneumoniae
#3
Toru Setsu, Atsunori Tsuchiya, Satoshi Yamagiwa, Shuji Terai
No abstract text is available yet for this article.
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28943541/the-correlation-between-chest-x-ray-scores-and-the-clinical-findings-in-children-and-adults-with-mycoplasma-pneumoniae-pneumonia
#4
Takeshi Saraya, Takayasu Watanabe, Yayoi Tsukahara, Kosuke Ohkuma, Haruyuki Ishii, Hirokazu Kimura, Kunimasa Yan, Hajime Goto, Hajime Takizawa
Objective To compare the radiological and laboratory data of children and adults with Mycoplasma pneumoniae pneumonia (MPP) and to evaluate the correlation between the total affected lung area and the clinical findings. Methods We retrospectively examined the data from MPP patients who visited our hospital during the period from April 2006 to July 2014. All data were retrieved at the time of the diagnosis of MPP and were analyzed to investigate the correlation between the clinical findings and the total affected lung area using a chest X-ray scoring system...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28943342/mechanisms-of-platelet-activation-by-the-pneumococcus-and-the-role-of-platelets-in-community-acquired-pneumonia
#5
REVIEW
Ronald Anderson, Charles Feldman
There is increasing recognition of the involvement of platelets in orchestrating inflammatory responses, driving the activation of neutrophils, monocytes and vascular endothelium, which, if poorly controlled, may lead to microvascular dysfunction. Importantly, hyperreactivity of platelets has been implicated in the pathogenesis of myocardial injury and the associated particularly high prevalence of acute cardiovascular events in patients with severe community-acquired pneumonia (CAP), of which Streptococcus pneumoniae (pneumococcus) is the most commonly encountered aetiologic agent...
September 21, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28943281/predictors-of-prolonged-hospitalizations-in-pediatric-complicated-pneumonia
#6
Oded Breuer, Elie Picard, Naama Benabu, Ira Erlichman, Joel Reiter, Reuven Tsabari, David Shoseyov, Eitan Kerem, Malena Cohen-Cymberknoh
BACKGROUND: Pediatric community acquired complicated pneumonia (PCACP) is characterized by a prolonged clinical course but this may be highly variable. METHODS: A multicenter observational study was conducted in order to develop and validate a clinical prediction tool for prolonged hospitalizations in PCACP. The derivation and validation cohorts consisted of 144 and 169 patients with PCACP, respectively, hospitalized between the years 1997-2017 in three tertiary care hospitals...
September 21, 2017: Chest
https://www.readbyqxmd.com/read/28943270/investigation-of-nosocomial-pneumocystis-infections-usefulness-of-longitudinal-screening-of-epidemic-and-post-epidemic-pneumocystis-genotypes
#7
Gilles Nevez, Solène Le Gal, Natacha Noel, Alain Wynckel, Antoine Huguenin, Yohann Le Govic, Laurence Pougnet, Michèle Virmaux, Dominique Toubas, Odile Bajolet
BACKGROUND: Twenty-five patients, of whom 22 were renal transplant recipients, developed Pneumocystis jirovecii (P.jirovecii) infections at the nephrology department of Reims University Hospital (France) from September 2008 through October 2009, whereas only four sporadic cases had been diagnosed in this department over the 14 previous years. AIM: This outbreak was investigated by analyzing patient encounters and P.jirovecii types. METHODS: A transmission map was drawn up...
September 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28943175/a-promising-new-test-to-detect-streptococcus-pneumoniae-urinary-antigen
#8
C Loïez, C Duployez, F Wallet
BACKGROUND: Streptococcus pneumoniae is the main etiology of community-acquired pneumonia (CAP). A quick detection of urinary antigen helps in obtaining a documented result in case of Streptococcus pneumoniae CAP. METHODS: We compared the BinaxNOW(®)S. pneumoniae test with the new urinary antigen Sofia(®)S. pneumoniae FIA. We examined 133 urine samples. RESULTS: Of the 133 included and tested non-concentrated urine samples, BinaxNOW(®) and Sofia(®) tests yielded 122 and 113 negative results and 11 and 20 positive results, respectively...
September 21, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28943167/bordetella-bronchiseptica-infection
#9
M Ducours, P Rispal, M P Danjean, Y Imbert, E Dupont, E M Traissac, S Grosleron
OBJECTIVE: To collect data of all patients admitted to hospital with a positive test to Bordetella bronchiseptica between 2001 and 2015. METHODS: We performed a retrospective monocentric study of all hospitalized patients over the past 15 years with a positive test to B. bronchiseptica. RESULTS: Nine patients were included between 2001 and 2015; two presented with infectious relapses, i.e. a total of 14 positive test samples were observed...
September 21, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28943148/in-vivo-safety-evaluation-of-antibacterial-silver-chloride-nanoparticles-from-streptomyces-exfoliatus-icn25-in-zebrafish-embryos
#10
Appadurai Muthamil Iniyan, Rajaretinam Rajesh Kannan, Francis-Joseph Rosemary Sharmila Joseph, Thankaraj Rajam Jabila Mary, Mani Rajasekar, Puthenpurayil Chellappan Sumy, Arul Maximus Rabel, Dasnamoorthy Ramachandran, Samuel Gnana Prakash Vincent
Silver chloride nanoparticles were synthesized from the cell-free culture supernatant of Streptomyces strain using green synthesis approach with good yield. The nanoparticles were characterized by UV-Vis, IR, SEM, AFM and XRD techniques. These nanoparticles exhibited broad spectrum of antibacterial activity towards Methicillin-resistant Staphylococcus aureus, Methicillin sensitive S. aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumonia at ≤ 2 μg/ml minimal inhibitory concentrations...
September 21, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28943051/a-case-of-adult-congenital-laryngeal-cleft-asymptomatic-until-hypopharynx-cancer-treatment
#11
Kotaro Shimizu, Atsuhiko Uno, Kazuya Takemura, Naoki Ashida, Ryohei Oya, Takahiro Kitamura, Yukinori Takenaka, Yoshifumi Yamamoto
Laryngeal cleft is an anomaly of failed posterior closure of the larynx. Most cases are diagnosed and need treatment early in life due to respiratory and swallowing problems. We report an unusual case of a 66-year-old man with an asymptomatic laryngeal cleft until treatment for hypopharyngeal cancer. During concurrent chemoradiotherapy (CCRT), despite reduced tumor volume, he presented severe dysphagia and dyspnea, followed by severe pneumonia twice. Because CCRT had to be discontinued, a pharyngolaryngectomy was performed for the cancer treatment...
September 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28942952/persistent-impairment-on-spirometry-in-chronic-eosinophilic-pneumonia-a-longitudinal-observation-study-shizuoka-cep-study
#12
Yuzo Suzuki, Yoshiyuki Oyama, Hironao Hozumi, Shiro Imokawa, Mikio Toyoshima, Koshi Yokomura, Hidenori Nakamura, Shigeki Kuroishi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Naoki Koshimizu, Takashi Yamada, Kazutaka Mori, Masafumi Masuda, Toshihiro Shirai, Hiroshi Hayakawa, Mitsuhiro Sumikawa, Takeshi Johkoh, Takafumi Suda
BACKGROUND: Chronic eosinophilic pneumonia (CEP) is characterized by the accumulation of eosinophils in the lung with unknown etiology. Although systemic corticosteroid administration leads to dramatic improvement, nearly half the patients with CEP experience relapse and some develop persistent impairment of pulmonary function. However, predictive factors for this persistent impairment have not been determined. OBJECTIVE: To investigate the occurrence of persistent impairment of pulmonary function in CEP and determine its predictive factors...
September 21, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28942884/overexpression-of-il-38-protein-in-anticancer-drug-induced-lung-injury-and-acute-exacerbation-of-idiopathic-pulmonary-fibrosis
#13
Masaki Tominaga, Masaki Okamoto, Tomotaka Kawayama, Masanobu Matsuoka, Shinjiro Kaieda, Yuki Sakazaki, Takashi Kinoshita, Daisuke Mori, Akira Inoue, Tomoaki Hoshino
BACKGROUND: Interleukin (IL)-38, a member of the IL-1 family, shows high homology to IL-1 receptor antagonist (IL-1Ra) and IL-36 receptor antagonist (IL-36Ra). Its function in interstitial lung disease (ILD) is still unknown. METHODS: To determine the expression pattern of IL-38 mRNA, a panel of cDNAs derived from various tissues was analyzed by quantitative real-time PCR. Immunohistochemical reactivity with anti-human IL-38 monoclonal antibody (clone H127C) was evaluated semi-quantitatively in lung tissue samples from 12 patients with idiopathic pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP), 5 with acute exacerbation of IPF, and 10 with anticancer drug-induced ILD (bleomycin in 5 and epidermal growth factor receptor-tyrosine kinase inhibitor in 5)...
September 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28942469/early-versus-late-diagnosis-of-complement-factor-i-deficiency-clinical-consequences-illustrated-in-two-families-with-novel-homozygous-cfi-mutations
#14
Clara Franco-Jarava, Elena Álvarez de la Campa, Xavier Solanich, Francisco Morandeira-Rego, Virgínia Mas-Bosch, Marina García-Prat, Xavier de la Cruz, Andrea Martín-Nalda, Pere Soler-Palacín, Manuel Hernández-González, Roger Colobran
The complement system is an important effector arm of innate immunity and plays a crucial role in the defense against common pathogens. But effective defense and maintenance of homeostasis requires a careful balance between complement activation and regulation. Factor I (FI) is one of the most important regulators of the complement system. Complete FI deficiency is a rare autosomal recessive disorder typically resulting in severe, recurrent infection by encapsulated bacteria. In the present study, we describe two patients from unrelated families with complete FI deficiency diagnosed at very different ages: Patient 1 is a 60-year-old man who had experienced several severe infections (pneumonia, meningitis, sepsis) since childhood, one of which caused significant and permanent neurologic sequelae...
September 23, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28942199/metabolomic-findings-in-sepsis-as-a-damage-of-host-microbial-metabolism-integration
#15
REVIEW
Natalia V Beloborodova, Andrei Yu Olenin, Alisa K Pautova
Metabolomics globally evaluates the totality of the endogenous metabolites in patient's body, at the same time reflecting gene function, enzyme activity and degree of organ dysfunction in sepsis. The authors performed the analysis of the main chemical classes of low molecular weight compounds (amino acids, polyols, fatty acids, hydroxy acids, amines, nucleotides and their derivatives) that quantitatively distinguish patients with sepsis from healthy ones. The following keywords were used to find papers published in the Scopus and Web of Science databases from 2008 to 2015: (marker OR biomarker) AND (sepsis OR critical ill OR pneumonia OR hypoxia)...
September 15, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28942198/effect-of-antibiotics-administered-via-the-respiratory-tract-in-the-prevention-of-ventilator-associated-pneumonia-a-systematic-review-and-meta-analysis
#16
Frederico Castro Costa Póvoa, Pablo Cardinal-Fernandez, Israel Silva Maia, Maycon Moura Reboredo, Bruno Valle Pinheiro
PURPOSE: We evaluated the effect of antibiotics administered via the respiratory tract to prevent the ventilator-associated pneumonia (VAP) in mechanically ventilated (MV) patients. METHODS: We searched relevant articles for trials that evaluated the impact of prophylactic antibiotics administered through the respiratory tract on the occurrence of VAP. The end-point was the occurrence of VAP in MV patients. RESULTS: We included 6 comparative trials involving 1158 patients (632 received prophylactic antibiotic)...
September 18, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28942177/emergence-of-class-1-to-3-integrons-among-members-of-enterobacteriaceae-in-egypt
#17
Dina E Rizk, Areej M El-Mahdy
In spite of the role of integrons as the main contributor to multidrug resistance worldwide, their prevalence in Egypt is still underestimated. In this work, we announce the emergence of class 2 and 3 integrons among Enterobacteriacae isolates from Mansoura University Hospitals. Ninety-three clinical isolates were obtained from different clinical sources, among which 70% of E. coli, 94.8% of K. pneumoniae and 85.7% of Enterobacter spp. were assigned to be multidrug resistant (MDR). Subsequently, the occurrence of class 1-3 integrons was confirmed by multiplex PCR...
September 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28942077/transcervical-extended-mediastinal-lymphadenectomy-experience-from-a-north-american-cancer-center
#18
Sai Yendamuri, Athar Battoo, Grace Dy, Hongbin Chen, Jorge Gomez, Anurag K Singh, Mark Hennon, Chukwumere E Nwogu, Elisabeth U Dexter, Miriam Huang, Anthony Picone, Todd L Demmy
BACKGROUND: Accurate staging of the mediastinum is a critical element of therapeutic decision making in non-small cell lung cancer. We sought to determine the utility of transcervical extended mediastinal lymphadenectomy (TEMLA) in staging non-small cell lung cancer for large central tumors and after induction therapy. METHODS: A retrospective record review was performed of all patients who underwent TEMLA at our institution from 2010 to 2015. Clinical stage as assessed by positron emission tomography integrated with computed tomography (PET-CT), stage as assessed by TEMLA, final pathologic stage, lymph node yield, and clinical characteristics of tumors were assessed along with TEMLA-related perioperative morbidity...
September 21, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28941825/expression-and-purification-of-functionally-active-ferrous-iron-transporter-feob-from-klebsiella-pneumoniae
#19
Aaron T Smith, Alexandrea E Sestok
The acquisition of ferrous iron (Fe(2+)) is an important virulence factor utilized by several hospital-acquired (nosocomial) pathogens such as Klebsiella pneumoniae to establish infection within human hosts. Virtually all bacteria use the ferrous iron transport system (Feo) to acquire ferrous iron from their environments, which are often biological niches that stabilize Fe(2+) relative to Fe(3+). However, the details of this process remain poorly understood, likely owing to the few expression and purification systems capable of supplying sufficient quantities of the chief component of the Feo system, the integral membrane GTPase FeoB...
September 20, 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/28941777/new-pyrimidine-based-ligand-capped-gold-and-platinum-nano-particles-synthesis-characterization-antimicrobial-antioxidant-dna-interaction-and-in-vitro-anticancer-activities
#20
M Sankarganesh, P Adwin Jose, J Dhaveethu Raja, M P Kesavan, M Vadivel, J Rajesh, R Jeyamurugan, R Senthil Kumar, S Karthikeyan
In this research work, we have synthesized new pyrimidine based Schiff base ligand, 2-((4,6-dimethoxypyrimidine-2-yl)methyleneenamino)-6-methoxyphenol (DPMM) capped gold (Au) and platinum (Pt) nanoparticles (NPs) by modified Brust-Schiffrin method. The characteristics of DPMM-Au NPs and DPMM-Pt NPs have been examined by UV-Visible, FTIR, SEM, TEM and powder XRD analysis. SEM analysis result shows that surface morphology of the DPMM-Au NPs and DPMM-Pt NPs are in granular and spherical shape, correspondingly...
September 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
keyword
keyword
31412
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"