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https://www.readbyqxmd.com/read/29655492/isolated-acute-appendicitis-caused-by-aspergillus-in-a-patient-who-underwent-lung-transplantation-a-case-report
#1
H S Kim, H J Yeo, D H Shin, W H Cho, D Kim
Invasive aspergillosis is an important cause of morbidity and mortality in patients who have undergone lung transplantation. Aspergillus infections usually involve the respiratory tract, with vascular invasion and subsequent dissemination. However, acute appendicitis associated with localized aspergillosis is rare, especially among patients who have undergone prophylaxis with voriconazole. We present a case of primary Aspergillus appendicitis diagnosed by histologic examination in a patient who underwent lung transplantation...
April 11, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29653090/vascular-and-molecular-pharmacology-of-the-metabolically-stable-cgrp-analogue-sax
#2
Majid Sheykhzade, Bahareh Abdolalizadeh, Cassandra Koole, Darryl Scott Pickering, Karin Dreisig, Sara Ellinor Johansson, Balsam Kadri Abboud, Rasmus Dreier, Jais Oliver Berg, Jørgen Lykke Jeppesen, Patrick M Sexton, Lars Edvinsson, Denise Wootten, Anette Sams
The main purpose of this study was to compare in vitro pharmacological properties of human αCGRP (CGRP) and a recently discovered metabolically stable CGRP analog, SAX, in isolated rat and human artery segments. In rat, CGRP and SAX induced similar vasodilatory responses in isolated mesenteric artery with the potency of SAX being lower than that of CGRP (vasodilatory pEC50 8.2 ± 0.12 and 9.0 ± 0.11, respectively). A corresponding difference in receptor binding affinity of SAX and CGRP was determined in rat cerebral membranes (pKi 8...
April 10, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29652940/functionality-of-cow-milk-naturally-enriched-with-polyunsaturated-fatty-acids-and-polyphenols-in-diets-for-diabetic-rats
#3
Emerson H Yoshimura, Nadine W Santos, Erica Machado, Bruna C Agustinho, Lucelia M Pereira, Sílvia C de Aguiar, Anacharis B Sá-Nakanishi, Cecília E Mareze-da-Costa, Lucia M Zeoula
The increasing incidence of diabetes mellitus is becoming a serious threat to human health in various parts of the world. Studies with dairy products have shown a potential beneficial effect against diabetes. This experiment evaluated the supplementation of milk naturally enriched with polyunsaturated fatty acids (PUFA) and polyphenols in rats with streptozotocin-induced diabetes. Forty male 28-day-old Wistar rats were distributed in four experimental treatments of diabetic animals (streptozotocin induction) and a normal group (non-induced)...
2018: PloS One
https://www.readbyqxmd.com/read/29652914/intestinal-manipulation-affects-mucosal-antimicrobial-defense-in-a-mouse-model-of-postoperative-ileus
#4
Kathy Stein, Lena Hieggelke, Bianca Schneiker, Mariola Lysson, Burkhard Stoffels, Sabine Nuding, Jan Wehkamp, Judith Kikhney, Annette Moter, Joerg C Kalff, Sven Wehner
AIM: To explore the effects of abdominal surgery and interleukin-1 signaling on antimicrobial defense in a model of postoperative ileus. METHODS: C57BL/6 and Interleukin-1 receptor type I (IL-1R1) deficient mice underwent intestinal manipulation to induce POI. Expression of mucosal IL-1α, IL-1β and IL-1R1 and several antimicrobial peptides and enzymes were measured by quantitative PCR or ELISA, western blotting or immunohistochemistry. Bacterial overgrowth was determined by fluorescent in-situ hybridization and counting of jejunal luminal bacteria...
2018: PloS One
https://www.readbyqxmd.com/read/29651794/celiac-trunk-and-common-hepatic-artery-variations-in-children-an-analysis-with-ct-angiography
#5
Emine Caliskan, Turker Acar, Mehmet Ozturk, Zuhal Bayramoglu, Ravza Yilmaz, Filiz Elbuken, Ibrahim Adaletli
BACKGROUND: Understanding the celiac trunk and hepatic artery anatomy is important not only in preventing iatrogenic injuries but also in planning surgical procedures in children. Therefore, the aim of this study is to analyze the prevalence of celiac trunk (CeT) and common hepatic artery (CHA) variations in the pediatric population. MATERIALS AND METHODS: One hundred and seventy-four children (174) who underwent abdominal multidetector computed tomography (MDCT) angiography, either because of trauma or liver transplantation, were analyzed retrospectively...
April 13, 2018: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/29650939/-a-case-of-successful-treatment-with-gemcitabine-plus-nab-paclitaxel-therapy-for-nonresected-pancreatic-body-cancer-stage-ivb
#6
Jun Kaneko, Ayako Kamiya, Kenta Kobayashi, Yasushi Takatsuno, Ito Kondoh, Kentaro Maejima, Jun Isogai, Kumi Hasegawa, Takeshi Endo, Shizuaki Maejima
A 61-year-old woman was introduced for consultation with a chief complaint of frequent vomiting. CT revealed a pancreatic body cancer approximately 40mm in size; an invading stenosis from the horizontal part of the duodenum to the jejunum, superior mesenteric artery, and portal vein, splenic vein obstruction, lymphadenopathy, and some ascitic fluid. We diagnosed a passage disorder due to the invasive stenosis from the horizontal part of the duodenum of the pancreatic body cancer to the jejunum, and subsequently performed a duodenum and jejunum bypass operation...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650856/-a-case-of-performed-right-colectomy-with-pancreato-duodenectomy-for-transverse-colon-cancer-invased-to-duodenum
#7
Ryutaro Udo, Masanobu Enomoto, Kazushige Tsurui, Yuu Kuboyama, Hiroshi Kuwabara, Masatoshi Shigoka, Tetsuo Ishizaki, Kenji Katsumata, Hiyo Obikane, Akihiko Tsuchida
There is a clear consensus regarding the combined resection of organs with cancer invasion, patients with colon cancer. However, there are very few reports to our knowledge regarding the use of pancreato-duodenectomy(PD)for colon cancer patients with cancer invasion in the duodenum. We here report a colon cancer patient in whom we performed PD and right hemicolectomy, who showed favorable results with no recurrence. The patient was a 69-year-old woman. Her chief complaint was hypogastric pain. Her previous doctor performed colonoscopy and a colonoscopic biopsy, and detected a type 2 lesion, throughout the entire circumference of the transverse colon near the liver, and she was diagnosed with adenocarcinoma...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650526/flushing-disorders-associated-with-gastrointestinal-symptoms-part-2-systemic-miscellaneous-conditions
#8
REVIEW
Vaibhav Rastogi, Devina Singh, Joseph J Mazza, Dennis Yang, Dipendra Parajuli, Steven H Yale
Flushing disorders with involvement of the gastrointestinal tract represent a heterogeneous group of conditions. In part 1 discussed were neuroendocrine tumors (NET), mast cell activation disorders (MCAD), and hyperbasophilia. In this section are covered the remaining flushing disorders which primarily or secondarily involves the gastrointestinal tract. This includes dumping syndrome, mesenteric traction syndrome, rosacea, hyperthyroidism and thyroid storm, anaphylaxis, panic disorders, paroxysmal extreme pain disorder, and food, alcohol and medications...
April 12, 2018: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29650525/flushing-disorders-associated-with-gastrointestinal-symptoms-part-1-neuroendocrine-tumors-mast-cell-disorders-and-hyperbasophila
#9
REVIEW
Vaibhav Rastogi, Devina Singh, Joseph J Mazza, Dennis Yang, Dipendra Parajuli, Steven H Yale
Flushing is the subjective sensation of warmth accompanied by visible cutaneous erythema occurring throughout the body with a predilection for the face, neck, pinnae, and upper trunk where the skin is thinnest and cutaneous vessels are superficially located and in greatest numbers. Flushing can be present in either a wet or dry form depending upon whether neural-mediated mechanisms are involved. Activation of the sympathetic nervous system results in wet flushing, accompanied by diaphoresis, due to concomitant stimulation of eccrine sweat glands...
April 12, 2018: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29649954/anatomical-considerations-and-open-surgery-to-treat-juxtarenal-abdominal-aortic-aneurysms
#10
Georgiana Samoila, Ian Michael Williams
INTRODUCTION: Historically, the open approach to the abdominal aorta has been transperitoneal (TP). In comparison, a retroperitoneal (RP) incision exposes the lateral wall of the suprarenal aorta for clamp application and midline structures such as the duodenum and pancreas are not encountered. Proximal clamp position for open repair of juxtarenal abdominal aortic aneurysm (JR-AAA) is suprarenal, supra-superior mesenteric, or supraceliac. While RP and TP approaches have previously been compared for physiological reasons, there are currently no randomized controlled trials comparing these methods from an anatomical perspective...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29649750/yersinia-enterocolitica-in-a-brazilian-pork-production-chain-tracking-of-contamination-routes-virulence-and-antimicrobial-resistance
#11
Bruna Torres Furtado Martins, Clarisse Vieira Botelho, Danilo Augusto Lopes Silva, Frederico Germano Piscitelli Alvarenga Lanna, Juliana Libero Grossi, Maria Emilene Martino Campos-Galvão, Ricardo Seiti Yamatogi, Juliana Pfrimer Falcão, Luciano Dos Santos Bersot, Luís Augusto Nero
This study aimed to track Yersinia enterocolitica contamination in a pork production chain in Minas Gerais, Brazil, and to characterize the virulence and antibiotic resistance of isolates. Samples were collected from four different steps of the pork production chain (pig farm, carcass, processing environment and end product; n = 870), and tested for the presence of Y. enterocolitica. The pathogen was detected in 8 samples (palatine tonsils = 5; mesenteric lymph nodes = 2; carcass after bleeding = 1), from which 16 isolates were obtained and identified as Y...
April 3, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29648971/anti-inflammatory-effects-of-a-mixture-of-lactic-acid-bacteria-and-sodium-butyrate-in-atopic-dermatitis-murine-model
#12
Jeong A Kim, Sung-Hak Kim, In Sung Kim, Da Yoon Yu, Sung Chan Kim, Seung Ho Lee, Sang Suk Lee, Cheol-Heui Yun, In Soon Choi, Kwang Keun Cho
Atopic dermatitis is a chronic and recurrent inflammatory skin disease. Recently, probiotics have been shown to suppress allergic symptoms through immunomodulatory responses. In the present study, combinatorial effects on allergic symptoms were identified in BALB/c mice fed with a mixture of four species of probiotics, Bifidobacterium lactis, Lactobacillus casei, Lactobacillus rhamnosus, and Lactobacillus plantarum, and sodium butyrate. Following sensitization with whey protein, the mice were challenged and divided into two groups: (1) mice administered with phosphate-buffered saline as a control and (2) mice administered with the probiotic mixture and sodium butyrate...
March 20, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29644270/importance-of-the-capability-for-complete-resuscitative-treatment-combining-surgery-and-interventional-radiology-for-potentially-lethal-multiple-injuries-a-case-report
#13
Hiroyuki Otsuka, Toshiki Sato, Keiji Sakurai, Hiromichi Aoki, Takeshi Yamagiwa, Shinichi Iizuka, Sadaki Inokuchi
Background: Recently, trauma management has been complicated owing to the introduction of damage-control strategies and interventional radiology. Here, we discuss important aspects regarding survival of patients with severe trauma. Case presentation: A 74-year-old Japanese woman experienced a traffic accident on a highway. On arrival, paramedics were unable to measure her blood pressure, and her condition deteriorated. The patient was immediately transferred to our hospital in a physician-staffed emergency helicopter, during which she was administered emergency blood transfusions...
October 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29644266/ureteric-transection-secondary-to-penetrating-handlebar-injury
#14
K P Debbink, D B Tashjian, M V Tirabassi, R Gaffey, J Nahmias
Ureteric trauma is rare, occurring in < 1% of all traumas. We present a unique case of a 13 year old female who sustained a penetrating abdominal injury from a bicycle handlebar. Upon initial examination there was herniation of bowel through the abdominal wound, so exploratory laparotomy was performed. A serosal injury of the colon and bleeding mesenteric veins were encountered; the retroperitoneum was not explored at that time. Postoperative course was remarkable for a doubling of the serum creatinine, increasing abdominal distention and pain...
August 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29644111/a-rare-combined-variation-of-the-coeliac-trunk-renal-and-testicular-vasculature
#15
Renate Elke Potgieter, Adam Michael Taylor, Quenton Wessels
The authors report a rare variation of the coeliac trunk, renal and testicular vasculature in a 27-year-old male cadaver. In the present case, the coeliac trunk and superior mesenteric artery was replaced by a modified coeliacomesenteric trunk formed by hepato-gastric and superior mesenteric arteries. Here the hepato-gastric artery or trunk contributed towards the total hepatic inflow as well as a gastro-duodenal artery. A separate right gastric artery and an additional superior pancreatico-duodenal artery was also found in addition with a retro-aortic left renal vein and a bilateral double renal arterial supply...
March 2018: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/29644005/radiofrequency-assisted-pancreaticoduodenectomy-for-palliative-surgical-resection-of-locally-advanced-pancreatic-adenocarcinoma
#16
Jayant Kumar, Isabella Reccia, Mikael H Sodergren, Tomokazu Kusano, Artur Zanellato, Madhava Pai, Duncan Spalding, Dimitris Zacharoulis, Nagy Habib
Background: Despite careful patient selection and preoperative investigations curative resection rate (R0) in pancreaticoduodenectomy ranges from 15% to 87%. Here we describe a new palliative approach for pancreaticoduodenectomy using a radiofrequency energy device to ablate tumor in situ in patients undergoing R1/R2 resections for locally advanced pancreatic ductal adenocarcinoma where vascular reconstruction was not feasible. Results: There was neither postoperative mortality nor significant morbidity...
March 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29643992/description-of-organ-specific-phenotype-and-functional-characteristics-of-tissue-resident-lymphocytes-from-liver-transplantation-donor-and-research-on-immune-tolerance-mechanism-of-liver
#17
Yunpeng Shi, Ping Zhang, Guangyi Wang, Xingkai Liu, Xiaodong Sun, Xin Zhang, Haijun Li, Jun Qi, Lei Ding, Ting Li, Ruoyan Zhang, Yuguo Chen, Jianpeng Zhou, Guoyue Lv, Zhengkun Tu
Aim: Prior to transplantation, Donation after Cardiac Death (DCD) liver transplantation livers are perfused with preservation solution. Therefore, this provides an abundant source of human liver lymphocytes, as well as mesenteric lymph node and spleen for the study of lymphocyte subset diversity in the peripheral blood, lymph node, spleen and liver. Methods: Lymphocyte subsets were isolated and purified from peripheral blood, lymph node, spleen and liver perfusion, the phenotypic and functional analysis of the tissue resident lymphocyte were performed by flow cytometry...
March 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29643328/superior-mesenteric-artery-syndrome-in-patients-with-crohn-s-disease-a-description-of-2-cases-studied-with-a-novel-magnetic-resonance-enterography-mre-procedure
#18
Giuseppe Cicero, Tommaso D'Angelo, Antonio Bottari, Giuseppe Costantino, Carmela Visalli, Sergio Racchiusa, Maria Adele Marino, Marco Cavallaro, Luciano Frosina, Alfredo Blandino, Silvio Mazziotti
BACKGROUND Superior mesenteric artery syndrome is caused by vascular compression of the third portion of the duodenum between the aorta and the superior mesenteric artery. It may occur with acute or chronic symptomatology, such as vomiting or postprandial abdominal pain, and it is usually caused by a lack of mesenteric fat pad under conditions of severe weight loss. Crohn's disease can be one of them. CASE REPORT We report 2 cases of Crohn's disease patients with clinical suspicion of jejunal stricture who underwent MR-enterography with a novel approach...
April 12, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29630087/evaluation-of-all-surgical-margins-in-pancreatic-resection-specimens-by-proper-grossing-techniques-surgical-pathology-experience-of-285-cases
#19
Özgür Ekinci
OBJECTIVE: The aim of this study was to review our series of pancreatic resection specimen handling results and focus on the positivity of the tumor in various retroperitoneal surgical margins. MATERIAL AND METHOD: Our archival cases from 2008 to 2018 were retrospectively examined, especially for the surgical margins. The demographics, tumor locations, and the diagnoses were recorded. The state of all of the retropancreatic surgical margins (anterior, posterior, superior, inferior, superior mesenteric vein and artery) were recorded...
April 9, 2018: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/29629356/feasibility-and-oncologic-safety-of-low-ligation-of-inferior-mesenteric-artery-with-d3-dissection-in-ct3n0m0-sigmoid-colon-cancer
#20
Kyung Ha Lee, Jin Soo Kim, Ji Yeon Kim
Purpose: There is no standard consensus for the ligation level of the inferior mesenteric artery during radical resection of sigmoid colon cancer. Especially, there is little research about low ligation combined with D3 dissection. The study was performed to compare feasibility and oncologic safety between low ligation with D3 dissection to high ligation in intermediately advanced sigmoid colon cancer. Methods: From January 2008 to December 2013, 134 patients who underwent radical surgery for cT3N0M0 sigmoid colon cancer were evaluated retrospectively...
April 2018: Annals of Surgical Treatment and Research
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