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https://www.readbyqxmd.com/read/29791596/treatment-with-ilex-paraguariensis-yerba-mate-aqueous-solution-prevents-hepatic-redox-imbalance-elevated-triglycerides-and-microsteatosis-in-overweight-adult-rats-that-were-precociously-weaned
#1
E de Oliveira, N S Lima, E P S Conceição, N Peixoto-Silva, E G Moura, P C Lisboa
Early weaning (EW) leads to overweight, visceral obesity, hyperleptinemia, and insulin resistance in adulthood. Treatment with Ilex paraguariensis (yerba mate) improves obesity and insulin resistance in these animals. Here, we evaluated the effects of chronic treatment with yerba mate on the redox balance and liver morphology of overweight early-weaned rats. To induce EW, we wrapped the dams with bandages to interrupt milk access during the last 3 days of lactation. Control pups (C) had free access to maternal milk for the full 21 days of lactation...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29788154/macrovascular-decompression-of-facial-nerve-with-anteromedial-transposition-of-a-dolichoectatic-vertebral-artery-3-dimensional-operative-video
#2
Halima Tabani, Sonia Yousef, Jan-Karl Burkhardt, Sirin Gandhi, Arnau Benet, Michael T Lawton
Most cranial nerve compression syndromes (ie, trigeminal neuralgia and hemifacial spasm) are caused by small arteries impinging on a nerve and are relieved by microvascular decompression. Rarely, cranial nerve compression syndromes can be caused by large artery impingement and can be relieved by macrovascular decompression. When present, this compression often occurs in association with degenerative atherosclerosis in the vertebral arteries (VA) and basilar artery. Conservative treatment is recommended for mild forms, but surgical transposition of the VA away from the root entry zone (REZ) can be considered...
May 21, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29786677/-combined-rehabilitation-in-the-patients-presenting-with-dorsopathies-of-the-lumbar-spine-and-concomitant-irritable-bowel-syndrome-based-at-a-therapeutic-clinic
#3
E V Sevostyanova, Y A Nikolaev, N V Bogdankevich, V G Lusheva, N A Dolgova, V Y Polyakov
BACKGROUND: Comorbidity constitutes a serious challenge for rehabilitative medicine. The comorbidity of the dorsopathy of the lumbar spine and irritable bowel syndrome mutually complicates the clinical course of both conditions, significantly reduces the patients' quality of life. and increases the costs of diagnostic procedures and restoration of the working capacity. The approaches to the non-pharmacological management of the patients presenting with these diseases remain to be developed...
May 21, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29784343/facile-synthesis-of-ni-based-metal-organic-frameworks-wrapped-mno-2-nanowires-with-high-performance-toward-electrochemical-oxygen-evolution-reaction
#4
Yujie Han, You Yu, Lingling Zhang, Liang Huang, Junfeng Zhai, Shaojun Dong
The transition metal oxides based catalysts have drawn great attention for their application in the electrolysis of water for renewable energy generation. Although manganese oxides were rarely used as oxygen evolution reaction (OER) catalysts, they were still considered as active and efficient OER catalysts due to the earth-abundant and low toxic nature of manganese. In this work, we proposed a facile method for the synthesis of high-performance electrochemical OER catalyst by magnetically stirring the mixture of 1,3,4-thiadiazole-2,5-dithiol (DMTD), Ni2+ and MnO2 nanowires (NWs) in ethanol at room temperature, noted as Ni/DMTD/MnO2 ...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29783180/reprint-of-cling-film-plastic-wrap-an-innovation-for-dead-body-packaging-preservation-and-transportation-by-first-responders-as-a-replacement-for-cadaver-body-bag-in-large-scale-disasters
#5
Lay See Khoo, Poh Soon Lai, Mohd Hilmi Saidin, Zahari Noor, Mohd Shah Mahmood
Cadaver body bags are the conventional method to contain a human body or human remains, which includes the use for storage and transportation of the deceased at any crime scene or disaster scene. During disasters, most often than not, the first responders including the police will be equipped with cadaver body bags to do scene processing of human remains and collection of personal belongings at the disaster site. However, in an unanticipated large scale disasters involving hundreds and thousands of fatalities, cadaver body bags supplies may be scarce...
May 18, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29782183/effect-of-cabbage-wraps-on-the-reduction-of-post-traumatic-knee-exudates-in-men
#6
Jacek Dygut, Monika Piwowar, Kinga Fijałkowska, Ibeth Guevara, Robert Jakubas, Gustaw Gonzales, Krzysztof Popławski, Anna Strokowska, Hanna Wikariak, Wiktor Jurkowski
OBJECTIVES: The study investigates measurable effects of cabbage leaf wraps on post-traumatic knee injury exudate absorption in men. DESIGN: Case-control experiment on the same group of patients (before and after treatment). SETTINGS/LOCATION: One academic center and two hospitals. SUBJECTS: The study was carried out on a group of patients with different degrees of injury severity in the acute stage of the knee injury who were divided into three groups based on the width of suprapatellar recess gap (3-5 mm in group 1, 6-10 mm in group 2, and 11 mm or more in group 3) as assessed by ultrasonography...
May 21, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29781456/how-can-a-personal-connection-build-confidence-in-your-graduate-nursing-journey
#7
Grace Tueffel
I wrapped my bright yellow stethoscope around my neck, pockets heavy with essential nursing tools and my clipboard clenched in my right hand. It was my first shift off orientation on the bone marrow transplantation unit at a teaching hospital in North Carolina. As I listened to the change-of-shift report, I felt my nerves on edge. I repeated "be the best nurse you can be" over and over in my head as I did my best to keep calm on that first day. That is what I remember from the first day and now, a few months later, I can reflect on what I learned and what "be the best nurse you can be" means to me...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29779644/development-of-a-novel-tissue-engineered-nitinol-frame-artificial-trachea-with-native-like-physical-characteristics
#8
Yasuto Sakaguchi, Toshihiko Sato, Yusuke Muranishi, Yojiro Yutaka, Teruya Komatsu, Koichi Omori, Tatsuo Nakamura, Hiroshi Date
BACKGROUND: Tracheal reconstruction is complicated by the short length to which a trachea can be resected. We previously developed a biocompatible polypropylene frame artificial trachea, but it lacked the strength and flexibility of the native trachea. In contrast, nitinol may provide these physical characteristics. We developed a novel nitinol frame artificial trachea and examined its biocompatibility and safety in canine models. METHODS: We constructed several nitinol frame prototypes and selected the frame that most closely reproduced the strength of the native canine trachea...
April 24, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29776169/effects-of-nucleosome-stability-on-remodeler-catalyzed-repositioning
#9
Aaron M Morgan, Sarah E LeGresley, Koan Briggs, Gada Al-Ani, Christopher J Fischer
Chromatin remodelers are molecular motors that play essential roles in the regulation of nucleosome positioning and chromatin accessibility. These machines couple the energy obtained from the binding and hydrolysis of ATP to the mechanical work of manipulating chromatin structure through processes that are not completely understood. Here we present a quantitative analysis of nucleosome repositioning by the imitation switch (ISWI) chromatin remodeler and demonstrate that nucleosome stability significantly impacts the observed activity...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775983/classification-and-microvascular-flap-selection-for-anterior-cranial-fossa-reconstruction
#10
James D Vargo, Wojciech Przylecki, Paul J Camarata, Brian T Andrews
BACKGROUND:  Microvascular reconstruction of the anterior cranial fossa (ACF) creates difficult challenges. Reconstructive goals and flap selection vary based on the defect location within the ACF. This study evaluates the feasibility and reliability of free tissue transfer for salvage reconstruction of low, middle, and high ACF defects. METHODS:  A retrospective review was performed. Reconstructions were anatomically classified as low (anterior skull base), middle (frontal bar/sinus), and high (frontal bone/soft tissue)...
May 18, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29775731/targeted-and-controlled-drug-delivery-by-multifunctional-mesoporous-silica-nanoparticles-with-internal-fluorescent-conjugates-and-external-polydopamine-and-graphene-oxide-layers
#11
Anh-Vy Tran, KyuHwan Shim, Thu-Thao Vo Thi, Jeong-Keun Kook, Seong Soo A An, Sang-Wha Lee
This study demonstrated the targeted delivery and controlled release of cisplatin drug molecules from doubly decorated mesoporous silica nanoparticles (MSNs), which were internally grafted with fluorescent conjugates and externally coated with polydopamine (PDA) and graphene oxide (GO) layers. The brush-like internal conjugates conferred fluorescent functionality and high capacity of cisplatin loading into MSNs, as well as contributing to a sustained release of the cisplatin through a porous channel with the assistance of external PDA layer...
May 15, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29775272/remarkable-enhancement-in-the-photoelectric-performance-of-uniform-flower-like-mesoporous-fe3o4-wrapped-in-nitrogen-doped-graphene-networks
#12
Jixin Yao, Kang Zhang, Wen Wang, Xueqin Zuo, Qun Yang, Huaibao Tang, Mingzai Wu, Guang Li
The porous structure and excellent specific surface area are superior for use as a counter electrode (CE) material. In addition, N-doped graphene possesses a remarkable electron-transfer pathway and many active sites. Therefore, a novel idea is to wrap uniform flower-like mesoporous Fe3O4 (Fe3O4UFM) in a N-doped graphene (N-RGO) network structure to enhance the power conversion efficiency (PCE). The hybrid materials of Fe3O4UFM@N-RGO are first used as a CE in dye-sensitized solar cells (DSSCs), showing a preeminent conductive interconnected 3D porous structure with more catalytic activity sites and a better ability for and a faster reaction rate of charge transfer, resulting in quicker reduction of I_3^- than Pt...
May 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29774921/a-flexible-pressure-sensor-based-on-rgo-polyaniline-wrapped-sponge-with-tunable-sensitivity-for-human-motion-detection
#13
Gang Ge, Yichen Cai, Qiuchun Dong, Yizhou Zhang, Jinjun Shao, Wei Huang, Xiaochen Dong
High-performance stretchable and wearable electronic skins (E-skins) with high sensitivity and a large sensing range are urgently required with the rapid development of the Internet of things and artificial intelligence. Herein, a reduced graphene oxide (rGO)/polyaniline wrapped sponge is prepared via rGO coating and the in situ synthesis of polyaniline nanowires (PANI NWs) on the backbones of sponge for the fabrication of pressure sensors. From the as-prepared flexible sensor, tunable sensitivity (0.042 to 0...
May 18, 2018: Nanoscale
https://www.readbyqxmd.com/read/29774594/in-vivo-characterization-of-3d-skull-and-brain-motion-during-dynamic-head-vibration-using-magnetic-resonance-elastography
#14
Ziying Yin, Yi Sui, Joshua D Trzasko, Phillip J Rossman, Armando Manduca, Richard L Ehman, John Huston
PURPOSE: To introduce newly developed MR elastography (MRE)-based dual-saturation imaging and dual-sensitivity motion encoding schemes to directly measure in vivo skull-brain motion, and to study the skull-brain coupling in volunteers with these approaches. METHODS: Six volunteers were scanned with a high-performance compact 3T-MRI scanner. The skull-brain MRE images were obtained with a dual-saturation imaging where the skull and brain motion were acquired with fat- and water-suppression scans, respectively...
May 17, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29774203/small-rho-gtpases-and-the-effector-vipa-mediate-the-invasion-of-epithelial-cells-by-filamentous-legionella-pneumophila
#15
Akriti Prashar, María Eugenia Ortiz, Stefanie Lucarelli, Elizabeth Barker, Zohreh Tabatabeiyazdi, Feras Shamoun, Deepa Raju, Costin Antonescu, Cyril Guyard, Mauricio R Terebiznik
Legionella pneumophila (Lp) exhibits different morphologies with varying degrees of virulence. Despite their detection in environmental sources of outbreaks and in respiratory tract secretions and lung autopsies from patients, the filamentous morphotype of Lp remains poorly studied. We previously demonstrated that filamentous Lp invades lung epithelial cells (LECs) and replicates intracellularly in a Legionella containing vacuole. Filamentous Lp activates β1integrin and E-cadherin receptors at the surface of LECs leading to the formation of actin-rich cell membrane structures we termed hooks and membrane wraps...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29772976/effects-of-storage-conditions-and-duration-on-cobalamin-concentration-in-serum-samples-from-cats-and-dogs
#16
Jennifer Kempf, Roger H Melliger, Claudia E Reusch, Peter H Kook
OBJECTIVE To evaluate the effects of storage conditions and duration on cobalamin concentration in serum samples from dogs and cats. DESIGN Experiment. SAMPLE Serum samples from 9 client-owned cats and 9 client-owned dogs. PROCEDURES Serum harvested from freshly obtained blood samples was separated into 11 aliquots/animal. One aliquot (baseline sample) was routinely transported in light-protected tubes to the laboratory for cobalamin assay; each of the remaining aliquots was stored in a refrigerator (6°C; n = 5) or at room temperature (20°C) with exposure to daylight (5) for 24, 48, 72, 96, or 120 hours...
June 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29772927/design-and-simulation-of-novel-laparoscopic-renal-denervation-system-a-feasibility-study
#17
Eunbi Ye, Jinhwan Baik, Seunghyun Lee, Seon Young Ryu, Sunchoel Yang, Eue-Keun Choi, Won Hoon Song, Hyeong Dong Yuk, Chang Wook Jeong, Sung-Min Park
PURPOSE: In this study, we propose a novel laparoscopy-based renal denervation (RDN) system for treating patients with resistant hypertension. In this feasibility study, we investigated whether our proposed surgical instrument can ablate renal nerves from outside of the renal artery safely and effectively and can overcome the depth-related limitations of the previous catheter-based system with less damage to the arterial walls. METHOD: We designed a looped bipolar electrosurgical instrument to be used with laparoscopy-based RDN system...
May 18, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29772921/a-multicomponent-intervention-to-encourage-stair-use-in-municipal-buildings
#18
Brent W Moloughney, Gayle E Bursey, Rebecca B Fortin, Maria G Morais, Khanh Thi Dang
PURPOSE: Evaluate the incremental impact of environmental stairwell enhancements on stair usage in addition to prompts. DESIGN: Phased, nonrandomized, quasi-experimental intervention. SETTING: Two 6-story and one 8-story municipal government office buildings-each with 2 stairwells. PARTICIPANTS: Approximately 2800 municipal employees and 1000 daily visitors. INTERVENTION: All stairwells received door wraps and point-of-decision and wayfinding prompts...
January 1, 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29772727/why-two-on-the-role-of-a-symmetry-in-negative-supercoiling-of-dna-by-gyrase
#19
REVIEW
Dagmar Klostermeier
Gyrase is a type IIA topoisomerase that catalyzes negative supercoiling of DNA. The enzyme consists of two GyrA and two GyrB subunits. It is believed to introduce negative supercoils into DNA by converting a positive DNA node into a negative node through strand passage: First, it cleaves both DNA strands of a double-stranded DNA, termed the G-segment, and then it passes a second segment of the same DNA molecule, termed the T-segment, through the gap created. As a two-fold symmetric enzyme, gyrase contains two copies of all elements that are key for the supercoiling reaction: The GyrB subunits provide two active sites for ATP binding and hydrolysis...
May 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29771454/isolation-and-total-structure-determination-of-an-all-alkynyl-protected-gold-nanocluster-au144
#20
Zhen Lei, Jiao-Jiao Li, Xian-Kai Wan, Wen-Han Zhang, Quan-Ming Wang
otal structure determination of a ligand-protected gold nanocluster Au144 has been successfully carried out. The title nanocluster has the composition of Au144(C≡CAr)60 (1, Ar = 2-F-C6H4-). Cluster 1 exhibits a quasi-spherical Russian doll-like architecture, comprising a Au54 two-shelled Mackay icosahedron (Au12@Au42), which is further enclosed by a Au60 anti-Mackay icosahedral shell. The Au114 kernel is wrapped by thirty linear ArC≡C-Au-C≡CAr staple motifs. Absorption spectrum of 1 shows two bands at 560 and 620 nm, which is distinctly different from that of thiolated Au144, which was predicted to have an almost identical metal kernel and very similar ligands arrangement in 1...
May 17, 2018: Angewandte Chemie
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