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https://www.readbyqxmd.com/read/28813883/development-of-a-series-wrapping-cam-mechanism-for-energy-transfer-in-wearable-arm-support-applications
#1
Jeremiah S Schroeder, Joel C Perry
An estimated 17 million individuals suffer a stroke each year with over 5 million resulting in permanent disability. For many of these, the provision of gravity support to the impaired upper limb can provide significant and immediate improvement in arm mobility. This added mobility has the potential to improve arm function and user independence overall, but, so far, wearable arm supports have found only limited uptake by end-users. The reasons are unclear, but it is hypothesized that device uptake is strongly affected by aspects of arm support implementation such as added weight and volume and the effectiveness of the support provided...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812406/types-of-orbital-osteoma-a-descriptive-analysis
#2
Tayyab Afghani, Hassan Mansoor
AIMS: This study describes different types of orbital osteoma based on clinical per-operative morphology and radiological findings to facilitate communication between ophthalmologists and surgical management for a better patient outcome. MATERIALS AND METHODS: The study was conducted in the Orbit and Oculoplastics Department of Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan, from July 1, 2001 to June 30, 2014. A retrospective analysis of 520 diagnosed orbital tumours who presented to us was carried out and the prevalence of orbital osteoma was determined...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28812159/anatomical-and-embryological-perspectives-in-laparoscopic-complete-mesocoloic-excision-of-splenic-flexure-cancers
#3
Takeru Matsuda, Yasuo Sumi, Kimihiro Yamashita, Hiroshi Hasegawa, Masashi Yamamoto, Yoshiko Matsuda, Shingo Kanaji, Taro Oshikiri, Tetsu Nakamura, Satoshi Suzuki, Yoshihiro Kakeji
BACKGROUND: Laparoscopic complete mesocoloic excision (CME) with central vascular ligation for splenic flexure cancer is technically challenging because of its anatomical complexity. Although embryological and anatomical consideration should be helpful to perform CME in colorectal cancer surgery, such studies on the splenic flexure are lacking. METHODS: The splenic flexure is located embryologically between the terminal portion of the midgut and the beginning of the hindgut, and is supplied by the superior mesenteric and inferior mesenteric arteries...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28812023/use-of-a-polyethylene-bag-to-reduce-perioperative-regional-and-whole-body-heat-losses-in-low-birth-weight-neonates
#4
Pierre Tourneux, Estelle Durand, Amandine Pelletier, Laurent Ghyselen, Véronique Bach, Jean-Pierre Libert
In the delivery room, wrapping a low-birth-weight neonate (defined as ≤2.499 g) in a polyethylene bag reduces the risk of hypothermia. However, extended use of the bag (e.g., during neonatal surgery) might conceivably increase the risk of thermal stress and thus body overheating. Here, we assessed the efficacy of a polyethylene bag in infants assigned to wrap (W) or nonwrap (NW, control) groups during placement of a percutaneous vena cava catheter by applying a new mathematical model that calculates heat exchanges for covered and uncovered body segments...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28811860/the-apelin-receptor-apj-in-hematopoietic-stem-cells-progenitor-cells-in-the-early-stage-of-non-alcoholic-steatohepatitis
#5
Wataru Ando, Hiroaki Yokomori, Katsuya Otori, Masaya Oda
BACKGROUND: Non-alcoholic steatohepatitis (NASH) is characterized by hepatic steatosis and inflammation with or without fibrosis. The apelin receptor (APJ) is related to angiotensin-like-receptor 1 (AGTRL1). The present study aimed to evaluate APJ as an indicator of the pathophysiology of early-stage NASH. METHODS: APJ expression was evaluated in six tissue samples with histologically proven early-stage NASH using immunohistochemistry (IHC) and immunoelectron microscopy (IEM)...
September 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28810173/effect-of-haptic-sensory-input-through-a-fluttering-cloth-on-tandem-gait-performance
#6
Kazushige Oshita, Sumio Yano
This study investigated the effects of haptic sensory input through a fluttering cloth on balance control during locomotion. Twenty-one healthy men performed a tandem gait test for 4m with their eyes closed under two different conditions: (1) wearing only half or short tights (HT-condition), or (2) wearing a fluttering cloth that was wrapped around the waist and extended to the lower leg (CLOTH-condition). Participants performed two trials with a 3-min rest period. The first trial involved the HT-condition, whereas the second trial involved either the CLOTH-condition (n=11), or the HT-condition again (n=10)...
August 11, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28809504/influence-of-particle-size-and-loading-on-particle-accessibility-in-electrospun-poly-ethylene-oxide-and-zif-8-composite-fibers-experiments-and-theory
#7
Mitchell R Armstrong, Christopher Balzer, Bohan Shan, Bin Mu
Developing electrospun nanofiber/ nanoparticle composites (ENNCs) is an emerging strategy for immobilizing functional particles for a variety of applications. The radial location of the particle along the fiber, either at the surface or in the bulk, has implication into the resulting properties. To explore particle location along fibers, ZIF-8 impregnated poly(ethylene oxide) (PEO) nanofibers are formed by electrospinning particle suspensions. Fibers impregnated with two different ZIF-8 particle sizes (200 nm and 12...
August 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28809414/carrier-photogeneration-drift-and-recombination-in-a-semiconducting-carbon-nanotube-network
#8
A Eckstein, V Bertašius, V Jašinskas, I Namal, T Hertel, V Gulbinas
Charge carrier photogeneration, drift and recombination in thin film networks of polymer-wrapped (6,5)-single-wall carbon nanotubes (SWNTs) blended with phenyl-C61-butyric acid methyl ester (PCBM) have been investigated by using transient photocurrent and time-delayed collection field (TDCF) techniques. Three distinct transient photocurrent components on the nano- and microsecond timescales have been identified. We attribute the dominant (>50% of total extracted charge) ultrashort photocurrent component with a decay time below our experimental time-resolution of 2 ns to the intratube hole motion...
August 15, 2017: Nanoscale
https://www.readbyqxmd.com/read/28805991/molecular-recognition-mediated-transformation-of-single-chain-polymer-nanoparticles-into-crosslinked-polymer-films
#9
Clare Sarah Mahon, Christopher J McGurk, Scott M D Watson, Martin A Fascione, Chadamas Sakonsinsiri, William Bruce Turnbull, David Andrew Fulton
We describe single-chain polymer nanoparticles (SCNPs) possessing intramolecular dynamic covalent crosslinks that can transform into polymer films through a molecular recognition-mediated crosslinking process. The SCNPs utilize molecular recognition with surface-immobilized proteins to concentrate themselves upon a substrate, bringing the SCNPs into close spatial proximity with one another and allowing their dynamic covalent crosslinkers to undergo intra-to interpolymer chain crosslinking leading to the formation of polymeric film...
August 14, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28805395/a-strategy-for-the-co-assembly-of-co-axial-nanotube-polymer-hybrids
#10
Mingyang Ji, Mahesh B Dawadi, Alexandria R LaSalla, Yuan Sun, David A Modarelli, Jon Robert Parquette
Nanostructured materials having multiple, discrete domains of sorted components are particularly important to create efficient optoelectronics. The construction of multicomponent nanostructures from self-assembled components is exceptionally challenging due to the propensity of noncovalent materials to undergo structural reorganization in the presence of excipient polymers. This work demonstrates that polymer-nanotube composites comprised of a self-assembled nanotube wrapped with two conjugated polymers could be assembled using a layer-by-layer approach...
August 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28802535/the-effects-of-autologous-platelet-rich-fibrin-on-flexor-tendon-healing-in-a-rabbit-model
#11
Janice C Y Liao, Min He, Aaron W T Gan, Alphonsus K S Chong
PURPOSE: Platelet-rich plasma containing large amounts of growth factors is purported to increase repaired flexor tendon strength. However, the use of bovine thrombin has the risk of antibody formation. We evaluated the effects of the newer generation autologous platelet-rich fibrin (PRF) on flexor tendon healing. METHODS: We performed surgical repair of 32 flexor tendons from the index and ring digits of the hind paws of 8 New Zealand white rabbits. In the PRF group, the PRF membrane was either wrapped around or interposed between the repair sites...
August 9, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28801687/human-mesenchymal-stromal-cell-sheet-enhances-allograft-repair-in-a-mouse-model
#12
Xifu Shang, Bing Shu, Yongjun Wang, Zhengliang Luo, Guangxi Wang, Shane Barton, Massimo Max Morandi, Christopher Kevil, Yufeng Dong
To determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum in a femoral allograft mouse model similar to fresh passaged (P3) young MSCs. At 3 weeks after transplantation of MSC sheets, results showed more bony callus formed between allograft and host bone ends in both young P3 MSC and aged P10 MSC sheet-wrapped groups when compared to allograft alone. At 6 weeks, while both MSC sheet-wrapped allografts showed more bony callus formation when compared to allograft alone groups, the bony callus size in aged P10 MSC sheet groups was significantly less than young P3 MSC sheet groups...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28799278/fluoropolymer-nanosheet-as-a-wrapping-mount-for-high-quality-tissue-imaging
#13
Hong Zhang, Ami Masuda, Ryosuke Kawakami, Kenji Yarinome, Riku Saito, Yu Nagase, Tomomi Nemoto, Yosuke Okamura
In the field of biological microscopy technology, it is still a practical challenge to obtain high-quality tissue images, due to the tissue desiccation that occurs during observations without an effective sample mounting. Inspired by the use of plastic food wrap, this study proposes the use of polymer thin films (also known as nanosheets) to fix the tissue samples. Water-repellent nanosheets composed of the amorphous fluoropolymer CYTOP are prepared with adjustable thicknesses and their hydrophobicity, transparency, and adhesion strength are evaluated...
August 11, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28799252/the-impact-of-global-left-ventricular-afterload-on-left-ventricular-reverse-remodeling-after-aortic-valve-replacement
#14
Hisato Ito, Toru Mizumoto, Yu Shomura, Yasuhiro Sawada, Ko Kajiyama, Hideto Shimpo
BACKGROUND: Conventional indices such as prosthetic valve effective orifice area (EOA) or transvalvular pressure gradients (TPG) may be unreliable in predicting left ventricular (LV) reverse remodeling after aortic valve replacement (AVR). We hypothesized that the global LV afterload, including valvular and arterial impedance, could influence LV reverse remodeling after AVR. METHODS: Twenty-three consecutive aortic-stenosis patients (mean age, 76 ± 6.4 years) underwent isolated AVR using contemporary externally wrapped pericardial valves (19 mm, 10 patients; 21 mm 11; 23 mm, 2)...
August 11, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28798842/a-low-cost-plug-and-play-inertial-microfluidic-helical-capillary-device-for-high-throughput-flow-cytometry
#15
Xiao Wang, Hua Gao, Nadja Dindic, Necati Kaval, Ian Papautsky
Glass capillary tubes have been widely used in microfluidics for generating microdroplets and microfibers. Here, we report on the application of glass capillary to inertial focusing of microparticles and cells for high-throughput flow cytometry. Our device uses a commercially available capillary tube with a square cross-section. Wrapping the tube into a helical shape induces the Dean vortices that aid focusing of cells or microbeads into a single position. We investigated the inertial focusing of microbeads in the device at various Re and concentrations and demonstrated 3D focusing with ∼100% efficiency for a wide range of microparticle diameters...
January 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28798133/structure-of-histone-based-chromatin-in-archaea
#16
Francesca Mattiroli, Sudipta Bhattacharyya, Pamela N Dyer, Alison E White, Kathleen Sandman, Brett W Burkhart, Kyle R Byrne, Thomas Lee, Natalie G Ahn, Thomas J Santangelo, John N Reeve, Karolin Luger
Small basic proteins present in most Archaea share a common ancestor with the eukaryotic core histones. We report the crystal structure of an archaeal histone-DNA complex. DNA wraps around an extended polymer, formed by archaeal histone homodimers, in a quasi-continuous superhelix with the same geometry as DNA in the eukaryotic nucleosome. Substitutions of a conserved glycine at the interface of adjacent protein layers destabilize archaeal chromatin, reduce growth rate, and impair transcription regulation, confirming the biological importance of the polymeric structure...
August 11, 2017: Science
https://www.readbyqxmd.com/read/28795567/buckled-thin-film-transistors-and-circuits-on-soft-elastomers-for-stretchable-electronics
#17
Giuseppe Cantarella, Christian Vogt, Raoul Hopf, Niko Münzenrieder, Panagiotis Andrianakis, Luisa Petti, Alwin Daus, Stefan Knobelspies, Lars Büthe, Gerhard Troester, Giovanni A Salvatore
Although recent progress in the field of flexible electronics has allowed the realization of biocompatible and conformable electronics, systematic approaches which combine high bendability (< 3 mm bending radius), high stretchability ( > 3-4 %) and low complexity in the fabrication process are still missing. Here, we show a technique to induce randomly-oriented and customized wrinkles on the surface of a biocompatible elastomeric substrate, where Thin-Film Transistors (TFTs) and circuits (inverter and logic NAND gates) based on Amorphous-IGZO are fabricated...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28782560/glutamate-promotes-ssb-protein-protein-interactions-via-intrinsically-disordered-regions
#18
Alexander G Kozlov, Min Kyung Shinn, Elizabeth A Weiland, Timothy M Lohman
E. coli single strand (ss) DNA binding protein (SSB) is an essential protein that binds to ssDNA intermediates formed during genome maintenance. SSB homotetramers bind ssDNA in several modes that differ in occluded site size and cooperativity. High "unlimited" cooperativity is associated with the 35 site size ((SSB)35) mode at low [NaCl], whereas the 65 site size ((SSB)65) mode formed at higher [NaCl] (> 200mM), where ssDNA wraps completely around the tetramer, displays "limited" cooperativity forming dimers of tetramers...
August 3, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28782501/interaction-pathways-between-soft-lipid-nanodiscs-and-plasma-membranes-a-molecular-modeling-study
#19
Shixin Li, Zhen Luo, Yan Xu, Hao Ren, Li Deng, Xianren Zhang, Fang Huang, Tongtao Yue
Lipid nanodisc, a model membrane platform originally synthesized for study of membrane proteins, has recently been used as the carrier to deliver amphiphilic drugs into target tumor cells. However, the central question of how cells interact with such emerging nanomaterials remains unclear and deserves our research for both improving the delivery efficiency and reducing the side effect. In this work, a binary lipid nanodisc is designed as the minimum model to investigate its interactions with plasma membranes by using the dissipative particle dynamics method...
August 4, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28776762/vein-wrapping-facilitates-basic-fibroblast-growth-factor-induced-heme-oxygenase-1-expression-following-chronic-nerve-constriction-injury
#20
Naoya Hirosawa, Kentaro Uchida, Kazuki Kuniyoshi, Kenichi Murakami, Gen Inoue, Masayuki Miyagi, Yusuke Matsuura, Sumihisa Orita, Kazuhide Inage, Takane Suzuki, Masashi Takaso, Seiji Ohtori
The clinical efficacy of autologous vein wrapping for recurrent compressive neuropathy has been demonstrated; however, the underlying mechanisms of this technique remain unclear. Rats were divided into chronic constriction injury (CCI) and CCI + vein wrapping (CCI + VW) groups. Mechanical allodynia was evaluated using von Frey filaments. To identify the neuroprotective factors released from veins, basic fibroblast growth factor (bFGF) mRNA expression in veins was compared to that in the sciatic nerve...
August 4, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
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