keyword
https://read.qxmd.com/read/38491861/the-effect-of-laser-resistant-endotracheal-tube-design-on-airflow-dynamics-a-benchtop-and-clinical-study
#1
JOURNAL ARTICLE
Jessica M L Pagel, Adithya Reddy, Lucy Fitzgerald, Mohamed Tiouririne, Patrick O McGarey, Daniel B Quinn, James J Daniero
OBJECTIVE: Compare ventilation pressures of 2 endotracheal tube designs used in laser airway surgery in clinical practice and with a benchtop model to elucidate differences and understand the design elements that impact airflow dynamics. METHODS: Ventilatory and aerodynamic characteristics of the laser resistant stainless-steel endotracheal tube (LRSS-ET) design and the laser resistant aluminum-wrapped silicone endotracheal tube (LRAS-ET) design were compared. Ventilatory parameters were collected for 32 patients undergoing laser-assisted airway surgery through retrospective chart review...
March 16, 2024: Annals of Otology, Rhinology, and Laryngology
https://read.qxmd.com/read/38490972/surface-plasmonic-core-shell-nanostructures-in-surface-enhanced-raman-scattering-and-photocatalysis
#2
REVIEW
En Cao, Yi Cao, Mengtao Sun
Core-shell nanostructures are a typical material design. Usually, it consists of a core wrapped in a shell. It has attracted much attention due to its tunable structure and composition, high surface area, and high programmability. The properties and resonance frequency of their surface plasmons can be adjusted by regulating the shape, size, and composition of metal core-shell nanostructures. This interaction makes core-shell nanostructures an excellent platform for plasmon-enhanced optical effects. This Perspective explores the categories of core-shell nanostructures, their exchanges with excitons in two-dimensional materials, their spectrum-enhanced aspects, and prospects for future applications of core-shell nanostructures...
March 15, 2024: Analytical Chemistry
https://read.qxmd.com/read/38489574/five-week-low-intensity-blood-flow-restriction-rowing-improves-v%C3%AC-o2max-in-elite-rowers
#3
JOURNAL ARTICLE
Steffen Held, Ludwig Rappelt, Robert Rein, Jan-Philip Deutsch, Tim Wiedenmann, Lars Donath
Held, S, Rappelt, L, Rein, R, Deutsch, J-P, Wiedenmann, T, and Donath, L. Five-week, low-intensity, blood flow restriction rowing improves V̇o2max in elite Rowers. J Strength Cond Res XX(X): 000-000, 2024-This controlled intervention study examined the effects of low-intensity rowing with blood flow restriction (BFR) on maximal oxygen uptake (V̇o2max), peak power output during ramp testing (PPO), and 2000-m time trial performance (P2k). Eleven, highly elite, male rowers (22.1 ± 1.6 years; 92...
March 14, 2024: Journal of Strength and Conditioning Research
https://read.qxmd.com/read/38488110/protective-effect-of-pediococcus-pentosaceus-li05-on-diarrhea-predominant-irritable-bowel-syndrome-in-rats
#4
JOURNAL ARTICLE
Youhe Wu, Shengjie Li, Longxian Lv, Shiman Jiang, Lvwan Xu, Hui Chen, Lanjuan Li
Pediococcus pentosaceus Li05 (Li05) has demonstrated potential benefits in various intestinal and liver diseases, but its potential and mechanisms in relieving diarrhea have not been understood. The objective of this research was to examine the effects and mechanisms of Li05 in rats with diarrhea-predominant irritable bowel syndrome (IBS-D) induced by wrap restrain stress (WRS) and 4% acetic acid. The results demonstrated that Li05 effectively alleviated weight loss, visceral sensitivity and diarrhea in rats with IBS-D...
March 15, 2024: Food & Function
https://read.qxmd.com/read/38487468/a-catheterizable-serous-lined-urinary-outlet-associated-with-the-ileal-bladder-augmentation-abol-enein-and-ghoneim-procedure-a-safe-and-reliable-procedure-in-children
#5
JOURNAL ARTICLE
Hortense Alliot, Toussaint Tapsoba, Annabel Paye-Jaouen, Yaqoub Ashkanani, Eliane Josset-Raffet, Lise Natio, Matthieu Peycelon, Alaa El-Ghoneimi
PURPOSE: This study aims to evaluate the long-term outcome of the serous-lined extramural continent catheterizable outlet procedure (SLECCOP) associated with ileal bladder augmentation in children. METHODS: This was a monocentric and retrospective study (2002-2021) that included children (<18 years) undergoing the SLECCOP associated with W-shaped ileocystoplasty with a catheterizable channel (Abol-Enein and Ghoneim procedure). Patients who received other types of bladder augmentation or W-shaped ileocystoplasty without a catheterizable channel were excluded...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38486995/biomimetic-gemini-nanoimmunoregulators-orchestrated-for-boosted-photoimmunotherapy-by-spatiotemporally-modulating-pd-l1-and-tumor-associated-macrophages
#6
JOURNAL ARTICLE
Honglin Huang, Ningxi Li, Xiaodan Wei, Qingzhi Li, Junhan Guo, Geng Yang, Hong Yang, Lulu Cai, Yiyao Liu, Chunhui Wu
A novel strategy of not only stimulating the immune cycle but also modulating the immunosuppressive tumor microenvironment is of vital importance to efficient cancer immunotherapy. Here, a new type of spatiotemporal biomimetic "Gemini nanoimmunoregulators" was engineered to activate robust systemic photoimmunotherapy by integrating the triple-punch of amplified immunogenic cell death (ICD), tumor-associated macrophages (TAMs) phenotype reprogramming and programmed cell death ligand 1 (PD-L1) degradation. The "Gemini nanoimmunoregulators" PM@RM-T7 and PR@RM-M2 were constructed by taking the biocompatible mesoporous polydopamine (mPDA) as nanovectors to deliver metformin (Met) and toll-like receptor 7/8 agonist resiquimod (R848) to cancer cells and TAMs by specific biorecognition via wrapping of red blood cell membrane (RM) inlaid with T7 or M2 peptides...
March 2024: Acta Pharmaceutica Sinica. B
https://read.qxmd.com/read/38485021/magnesium-source-with-function-of-slowly-releasing-mg-and-ph-control-for-impurity-resistance-synthesis-ultra-large-struvite-from-wastewater
#7
JOURNAL ARTICLE
Tong Zhou, Naiguang Xu, Guangyuan Chen, Meng Zhang, Tuo Ji, Xin Feng, Changsong Wang
Struvite (MgNH4 PO4 ·6H2 O, Magnesium ammonium phosphate, MAP), recovered from wastewater, has potential application as a slow-release fertilizer. However, crystal size distribution (CSD) of recovered MAP typically lied in the range of 50-300 μm, due to fast nucleation rate and notably narrow metastable zone width (MSZW) of MAP, with purity levels 40-90 %. In order to control the rate of nucleation, a novel magnesium source with the form of MgHPO4 ·3H2 O wrapped with Mg(OH)2 was prepared, referred to as P-3...
March 12, 2024: Science of the Total Environment
https://read.qxmd.com/read/38485000/new-generation-mixed-matrix-membrane-for-co-2-separation-transition-from-binary-to-quaternary-mixed-matrix-membrane
#8
REVIEW
Mridusmita Barooah, Sukanya Kundu, Shubham Kumar, Aviti Katare, Rajashree Borgohain, Ramagopal V S Uppaluri, Lal Mohan Kundu, Bishnupada Mandal
Contemporary advances in material development associated with membrane gas separation refer to the cost-effective fabrication of high-performance, defect-free mixed matrix membranes (MMMs). For clean energy production, natural gas purification, and CO2 capture from flue gas systems, constituting a functional integration of polymer matrix and inorganic filler materials find huge applications. The broad domain of research and development of MMMs focused on the selection of appropriate materials, inexpensive membrane fabrication, and comparative study with other gas separation membranes for real-world applications...
March 12, 2024: Chemosphere
https://read.qxmd.com/read/38482791/biogelx-ikvav-is-an-innovative-hpl-adsc-delivery-strategy-to-improve-peripheral-nerve-repair
#9
JOURNAL ARTICLE
Martino Guiotto, Alison Clayton, Ryan Morgan, Wassim Raffoul, Andrew Hart, Mathis O Riehle, Pietro Summa
Adipose-derived stem cells (ADSC) are nowadays one of the most exploited cells in regenerative medicine. They are fast growing, capable of enhancing axonal elongation, support and locally stimulate Schwann cells (SC) and protect de-innervated muscles from atrophy after a peripheral nerve injury. With the aim of developing a bio-safe, clinically translatable cell-therapy, we assessed the effect of ADSC pre-expanded with human platelet lysate (hPL) in an in vivo rat model, delivering the cells into a 15 mm critical-size sciatic nerve defect embedded within a laminin-peptide-functionalised hydrogel (Biogelx-IKVAV) wrapped by a poly-"ℇ" -caprolactone (PCL) nerve conduit...
March 14, 2024: Tissue Engineering. Part A
https://read.qxmd.com/read/38479867/uoeh-international-symposium-2023-wrap-up-session-digital-technology-for-occupational-health
#10
JOURNAL ARTICLE
Ken Takahashi
In the wrap-up session, I synthesized insights from the conference presentations along with external references indicated by quotation marks (Reference: European Agency for Safety and Health at Work. Foresight on new and emerging occupational safety and health risks associated with digitalization by 2025. https://osha.europa.eu/sites/default/files/Foresight_new_OSH_risks_2025_summary.pdf).
2024: Journal of UOEH
https://read.qxmd.com/read/38479215/cookie-cravings-examining-the-impact-of-sugar-content-information-on-christmas-treat-preferences-via-mobile-eye-tracking
#11
JOURNAL ARTICLE
Jonas Potthoff, Christina Herrmann, Anne Schienle
BACKGROUND: Diets high in added sugar can promote the development of overweight. Especially during the Holiday season, when high-sugar food is abundant, people overeat and gain more weight than during other times of the year. The present study with mobile eye-tracking glasses (Pupil Labs Invisible) investigated how sugar content information affects food preference (liking/wanting) and visual attention (where and how long one is looking) in a buffet-like situation. METHODS: Fifty-eight participants who were well acquainted with the local Christmas traditions and foods (38 female, 19 male, one diverse; mean age = 25 years, SD = 6...
March 12, 2024: Acta Psychologica
https://read.qxmd.com/read/38479070/public-knowledge-of-button-battery-ingestions-a-social-media-based-cross-sectional-analysis
#12
JOURNAL ARTICLE
Justine Philteos, Yasmine Madan, Adrian L James, Evan J Propst, Olivia Ostrow, Nicole McKinnon, Tobias Everett, Jennifer Siu, Nikolaus E Wolter
INTRODUCTION: Button battery (BB) ingestion injuries are a devastating and preventable event within the pediatric population. Efforts to reduce the prevalence of esophageal button battery ingestion injuries include primary preventative measures. It is integral to assess the public's baseline knowledge about BB injuries to tailor future primary prevention efforts. METHODS: This is a crowdsourcing survey-based study. Participants were notified through our institution's Twitter and Instagram accounts...
March 2, 2024: International Journal of Pediatric Otorhinolaryngology
https://read.qxmd.com/read/38474877/effects-of-kiwifruit-dietary-fibers-on-pasting-properties-and-in-vitro-starch-digestibility-of-wheat-starch
#13
JOURNAL ARTICLE
Yaqi Wang, Yaoyi Pan, Chang Zhou, Wenru Li, Kunli Wang
In this study, the roles of kiwifruit soluble/insoluble dietary fiber (SDF/IDF, respectively) in the pasting characteristics and in vitro digestibility of wheat starch were explored. According to RVA and rheological tests, the IDF enhanced the wheat starch viscosity, decreased the gelatinization degree of the starch granules, and exacerbated starch retrogradation. The addition of SDF in high quantities could reduce the starch gelatinization level, lower the system viscosity, and exacerbate starch retrogradation...
March 5, 2024: Nutrients
https://read.qxmd.com/read/38473480/graphene-wrapped-zno-nanocomposite-with-enhanced-room-temperature-photo-activated-toluene-sensing-properties
#14
JOURNAL ARTICLE
Qingwu Huang, Jinjin Wu, Dawen Zeng, Peng Zhou
Graphene-wrapped ZnO nanocomposites were fabricated by a simple solvothermal technology with a one-pot route. The structure and morphology of these as-fabricated samples were systematically characterized. The adding of graphene enhanced the content of the oxygen vacancy defect of the sample. All gas-sensing performances of sensors based on as-prepared samples were thoroughly studied. Sensors displayed an ultrahigh response and exceptional selectivity at room temperature under blue light irradiation. This excellent and enhanced toluene gas-sensing property was principally attributed to the synergistic impacts of the oxygen vacancy defect and the wrapped graphene in the composite sensor...
February 22, 2024: Materials
https://read.qxmd.com/read/38472777/pickering-emulsion-stabilized-by-hordein-whey-protein-isolate-complex-delivery-system-of-quercetin
#15
JOURNAL ARTICLE
Songqi Yang, Yunan Jin, Feifan Li, Jinfeng Shi, Jiahui Liang, Xiaohong Mei
As a lipophilic flavonol, quercetin has low bioavailability, which limits its application in foods. This work aimed to prepare a hordein-based system to deliver quercetin. We constructed hordein-whey isolate protein fibril (WPIF) complexes (H-Ws) by anti-solvent precipitation method at pH 2.5. The TEM results of the complexes showed that spherical-like hordein particles were wrapped in WPIF clusters to form an interconnected network structure. FTIR spectra revealed that hydrogen bonds and hydrophobic interactions were the main driving forces for the complex formation...
February 22, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38470915/it-is-theoretically-possible-to-avoid-misfolding-into-non-covalent-lasso-entanglements-using-small-molecule-drugs
#16
JOURNAL ARTICLE
Yang Jiang, Charlotte M Deane, Garrett M Morris, Edward P O'Brien
A novel class of protein misfolding characterized by either the formation of non-native noncovalent lasso entanglements in the misfolded structure or loss of native entanglements has been predicted to exist and found circumstantial support through biochemical assays and limited-proteolysis mass spectrometry data. Here, we examine whether it is possible to design small molecule compounds that can bind to specific folding intermediates and thereby avoid these misfolded states in computer simulations under idealized conditions (perfect drug-binding specificity, zero promiscuity, and a smooth energy landscape)...
March 2024: PLoS Computational Biology
https://read.qxmd.com/read/38470853/programming-heterometallic-4f-4f-helicates-under-thermodynamic-control-the-circle-is-complete
#17
JOURNAL ARTICLE
Charlotte Egger, Laure Guénée, Neel Deorukhkar, Claude Piguet
Three non-symmetrical segmental ligand strands L4 can be wrapped around a linear sequence of one Zn2+ and two trivalent lanthanide cations Ln3+ to give quantitatively directional [ZnLn2 (L4)3 ]8+ triple-stranded helicates in the solid state and in solution. NMR speciations in CD3 CN show negligible decomplexation at a millimolar concentration and the latter helicate can be thus safely considered as a preorganized C 3 -symmetrical HHH -[(L43 Zn)(LnA )(2- n ) (LnB ) n ]8+ platform in which the thermodynamic properties of (i) lanthanide permutation between the central N9 and the terminal N6 O3 binding sites and (ii) exchange processes between homo- and heterolanthanide helicates are easy to access (Ln = La, Eu, Lu)...
March 12, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
https://read.qxmd.com/read/38470457/inverted-transflection-spectroscopy-of-live-cells-using-metallic-grating-on-elevated-nanopillars
#18
JOURNAL ARTICLE
Aditya Mahalanabish, Steven H Huang, Gennady Shvets
Water absorption of mid-infrared (MIR) radiation severely limits the options for vibrational spectroscopy of the analytes-including live biological cells-that must be probed in aqueous environments. While internal reflection elements, such as attenuated total reflection prisms and metasurfaces, partially overcome this limitation, such devices have their own limitations: ATR prisms are difficult to integrate with multiwell cell culture workflows, while metasurfaces suffer from a limited spectral range and small penetration depth into analytes...
March 12, 2024: ACS Sensors
https://read.qxmd.com/read/38470055/the-recruitment-of-tric-chaperonin-in-rotavirus-viroplasms-correlates-with-virus-replication
#19
JOURNAL ARTICLE
Janine Vetter, Guido Papa, Kurt Tobler, Javier M Rodriguez, Manuel Kley, Michael Myers, Mahesa Wiesendanger, Elisabeth M Schraner, Daniel Luque, Oscar R Burrone, Cornel Fraefel, Catherine Eichwald
UNLABELLED: Rotavirus (RV) replication takes place in the viroplasms, cytosolic inclusions that allow the synthesis of virus genome segments and their encapsidation in the core shell, followed by the addition of the second layer of the virion. The viroplasms are composed of several viral proteins, including NSP5, which serves as the main building block. Microtubules, lipid droplets, and miRNA-7 are among the host components recruited in viroplasms. We investigated the interaction between RV proteins and host components of the viroplasms by performing a pull-down assay of lysates from RV-infected cells expressing NSP5-BiolD2...
March 12, 2024: MBio
https://read.qxmd.com/read/38468182/a-device-related-fistula-between-coronary-artery-and-left-atrial-appendage-following-left-atrial-appendage-closure-case-presentation
#20
Xiaohua Liu, Yizhou Xu
INTRODUCTION: Left atrial appendage (LAA) closure (LAAC) is considered a viable alternative to anticoagulation therapy for stroke prevention in nonvalvular atrial fibrillation, we report a case with a less common shunt resulting from a device-related coronary artery-appendage fistula (CAAF) following LAAC. METHODS AND RESULTS: A 67-year-old male with a history of LAAC was referred to our emergency room with recurrent chest pain and palpitations and was diagnosed with ischemic angina pectoris...
March 11, 2024: Journal of Cardiovascular Electrophysiology
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