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Lymphadenitis

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https://www.readbyqxmd.com/read/28332028/infection-profile-in-chronic-granulomatous-disease-a-23-year-experience-from-a-tertiary-care-center-in-north-india
#1
Amit Rawat, Pandiarajan Vignesh, Avinash Sharma, Jitendra K Shandilya, Madhubala Sharma, Deepti Suri, Anju Gupta, Vikas Gautam, Pallab Ray, Shivaprakash M Rudramurthy, Arunaloke Chakrabarti, Kohsuke Imai, Shigeaki Nonoyama, Osamu Ohara, Yu L Lau, Surjit Singh
PURPOSE: Chronic granulomatous disease (CGD) is an inherited phagocytic disorder characterized by recurrent infections with usually catalase-positive organisms. Infections in CGD from developing countries are expected to be different from those in the Western countries. We report the profile of infections in children diagnosed with CGD from a tertiary care center in North India. METHODOLOGY: Case records of children diagnosed with CGD at Pediatric Immunodeficiency Clinic, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India, from August 1993 to April 2016 (23 years) were analyzed...
March 22, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28331133/infectious-mononucleosis-lymphadenitis-resembling-kikuchi-s-disease-cytological-histopathological-and-immunohistological-findings
#2
Atsuko Takada, Kazuhiko Shimizu, Yoshimasa Nakazato, Kensuke Ohikata, Shigeru Tsuchida, Misa Iijima, Masaru Kojima
No abstract text is available yet for this article.
2017: Journal of Clinical and Experimental Hematopathology: JCEH
https://www.readbyqxmd.com/read/28327085/a-shift-in-the-virulence-potential-of-corynebacterium-pseudotuberculosis-biovar-ovis-after-passage-in-a-murine-host-demonstrated-through-comparative-proteomics
#3
Wanderson M Silva, Fernanda A Dorella, Siomar C Soares, Gustavo H M F Souza, Thiago L P Castro, Núbia Seyffert, Henrique Figueiredo, Anderson Miyoshi, Yves Le Loir, Artur Silva, Vasco Azevedo
BACKGROUND: Corynebacterium pseudotuberculosis biovar ovis, a facultative intracellular pathogen, is the etiologic agent of caseous lymphadenitis in small ruminants. During the infection process, C. pseudotuberculosis changes its gene expression to resist different types of stresses and to evade the immune system of the host. However, factors contributing to the infectious process of this pathogen are still poorly documented. To better understand the C. pseudotuberculosis infection process and to identify potential factors which could be involved in its virulence, experimental infection was carried out in a murine model using the strain 1002_ovis and followed by a comparative proteomic analysis of the strain before and after passage...
March 22, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28325157/-a-preschooler-with-abdominal-pain-in-the-right-lower-quadrant
#4
J J Atema, B C Vrouenraets
A 5-year-old boy with acute abdominal pain in the right lower quadrant and fever underwent open appendectomy following clinical observation and serial equivocal ultrasound. During exploration we encountered a normal-looking appendix but multiple enlarged mesenteric lymph nodes, suggestive of mesenteric lymphadenitis. The boy had an uneventful postoperative course and recovered completely.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28323562/corynebacterium-pseudotuberculosis-infection-in-patagonian-huemul-hippocamelus-bisulcus
#5
Nelly Morales, Dennis Aldridge, Andrea Bahamonde, Julio Cerda, Claudio Araya, Rodrigo Muñoz, María Esther Saldías, Claudio Lecocq, Marcela Fresno, Pedro Abalos, Patricio Retamal
Corynebacterium pseudotuberculosis is an intracellular bacteria and the etiologic agent of caseous lymphadenitis in domestic and wildlife species. We report C. pseudotuberculosis infection in Patagonian huemul ( Hippocamelus bisulcus ) from the Cerro Castillo National Reserve, Region of Aysen, Chile. Subcutaneous abscesses in the abdominal and pectoral regions from two animals were sampled and bacteriologic isolation was performed. In both cases, we isolated a C. pseudotuberculosis strain belonging to the ovine genotype...
March 21, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28317809/treatment-outcome-in-children-with-nontuberculous-mycobacterial-lymphadenitis-a-retrospective-follow-up-study
#6
Annicka Reuss, Sarah Drzymala, Barbara Hauer, Rüdiger von Kries, Walter Haas
INTRODUCTION: Information on the long-term treatment outcome following nontuberculous mycobacterial (NTM) lymphadenitis is very limited. We performed a study to (a) compare cure rates following different initial treatment courses, (b) describe subsequent treatment courses and their outcomes, and (c) determine the occurrence of late sequelae in immunocompetent children with NTM lymphadenitis. MATERIALS AND METHODS: In 2011, we conducted a retrospective follow-up study in 71 parents whose children had been hospitalized with NTM disease 2002-2005...
January 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28293057/kikuchi-fujimoto-disease-a-rare-presentation-with-localized-iliac-lymphadenitis
#7
Shrihari Anil Anikhindi, Anil Arora, Shashi Dhawan, Naresh Bansal, Praveen Sharma, Vikas Singla, Ashish Kumar
Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease characterized by histiocytic necrotising lymphadenitis. Though several viral agents or an autoimmune etiology has been proposed as causative, the exact cause remains unknown. It has a female predilection and most commonly seen among young Asian people. Patients usually present with a febrile illness and the presence of lymphadenopathy may provide a clue to diagnosis. The most common site of lymphadenopathy is cervical lymph nodes while intra-abdominal involvement is uncommon...
January 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28284263/immune-thrombocytopenia-secondary-to-tuberculosis-a-case-and-review-of-literature
#8
S F Weber, S Bélard, S Rai, R Reddy, S Belurkar, K Saravu
Immune thrombocytopenia (ITP) is an auto-immune condition that results in isolated thrombocytopenia associated with possibly lethal haemorrhage. In its secondary form, ITP can be triggered by many infectious and non-infectious conditions. Secondary ITP associated with tuberculosis (TB) has rarely been described in the literature. We report on a 22-year-old patient presenting with hypermenorrhoea and petechiae due to ITP secondary to tuberculous lymphadenitis. Normalisation of thrombocytopenia was only achieved after initiation of anti-tuberculosis treatment following failure of thrombocyte substitution and immune-modulatory treatment...
April 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28279633/kikuchi-fujimoto-disease-a-rare-cause-of-lymphadenopathy-in-africa-description-of-the-first-case-in-senegal-and-review-of-the-literature
#9
C-A Lame, B Loum, A-K Fall, J Cucherousset, A-R Ndiaye
INTRODUCTION: Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is a benign disease most commonly affecting adult females. It generally presents in the form of febrile cervical lymphadenopathy. This diagnosis must be considered in the setting of tropical medicine, dominated by a high prevalence of tuberculous lymphadenitis and haematological malignancies. CASE REPORT: The authors report the case of a 33-year-old Senegalese woman who presented with subacute cervical lymphadenopathy associated with fever and laboratory signs of inflammation...
March 6, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28275091/endemic-caseous-lymphadenitis-in-a-wild-caprinae-population
#10
L Varela-Castro, J Lara-Vergara, N Ortega, J Salinas, A Colom-Cadena, S Lavín, P Tizzani, R Velarde, E Serrano, G Mentaberre
Between 2010 and 2013, an outbreak of caseous lymphadenitis (CLA) occurred in a captive stock of Iberian ibexes (Capra pyrenaica, Schinz 1838) maintained for conservation purposes in the National Game Reserve 'Ports de Tortosa i Beseit' (PTB), northeastern Spain. The aim of this study was to assess the CLA status in the free-ranging donor population of ibexes. An ELISA test to detect antibodies to CLA was performed in 360 hunter-harvested ibexes between 2007 and 2013. A spatial analysis and recursive partitioning approaches with regression tree models were used to explore CLA-associated risk factors...
March 8, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28271647/mycobacterium-kansasii-pneumonia-with-mediastinal-lymphadenitis-in-a-patient-with-acute-myeloid-leukemia-successful-treatment-to-stem-cell-transplantation
#11
Yeon Geun Choi, Sung Yeon Cho, Dong Gun Lee, Eunjung Yim, Hyonsoo Joo, Seongyul Ryu, Jae Ki Choi, Hee Je Kim
Non-tuberculous mycobacterial (NTM) disease is a relatively rare cause of neutropenic fever in patients with hematologic malignancies. During the neutropenic period, performing invasive procedures for microbiological or pathological confirmation is difficult. In addition, the optimal treatment duration for NTM disease in patients with leukemia, especially prior to stem cell transplantation (SCT), has not been documented. Therefore, we report a case of pneumonia with necrotizing lymphadenitis caused by Mycobacterium kansasii diagnosed during chemotherapy being performed for acute myeloid leukemia...
January 19, 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/28265761/risk-factors-of-non-tuberculous-mycobacterial-lymphadenitis-in-children-a-case-control-study
#12
Patricia W Garcia-Marcos, Mercedes Plaza-Fornieles, Ana Menasalvas-Ruiz, Ramon Ruiz-Pruneda, Pedro Paredes-Reyes, Santiago Alfayate Miguelez
The aim of the present study is to clarify the association between environmental exposures and non-tuberculous mycobacterial (NTM) lymphadenitis, during the last decade, in a population of children. In children up to 14 years of age in a pediatric tertiary hospital, all cases of NTM lymphadenopathy with a specific microbiological diagnosis, from January 2004 to January 2015, were reviewed. This is a case-control study (1:5 proportion), in which the prevalence of environmental factors between cases and controls was compared by means of a multivariate logistic regression analysis...
March 6, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28261620/acute-nonspecific-mesenteric-lymphadenitis-more-than-no-need-for-surgery
#13
REVIEW
Rossana Helbling, Elisa Conficconi, Marina Wyttenbach, Cecilia Benetti, Giacomo D Simonetti, Mario G Bianchetti, Flurim Hamitaga, Sebastiano A G Lava, Emilio F Fossali, Gregorio P Milani
Acute nonspecific, or primary, mesenteric lymphadenitis is a self-limiting inflammatory condition affecting the mesenteric lymph nodes, whose presentation mimics appendicitis or intussusception. It typically occurs in children, adolescents, and young adults. White blood count and C-reactive protein are of limited usefulness in distinguishing between patients with and without mesenteric lymphadenitis. Ultrasonography, the mainstay of diagnosis, discloses 3 or more mesenteric lymph nodes with a short-axis diameter of 8 mm or more without any identifiable underlying inflammatory process...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28260763/a-retrospective-histopathological-study-on-extra-pulmonary-tuberculosis-in-mymensingh
#14
A Begum, M A Baten, Z Begum, M M Alam, M M Ahsan, N P Ansari, S Zahan, M K Khan, F Nesa, M M Huq
Tuberculosis is a very common disease in our country. This retrospective histopathological study was designed to assess the distribution of extra-pulmonary tuberculosis (EPTB) in various organs through examination of biopsy specimens. A total of 216 specimens were diagnosed as tubercular lesion by histopathological evaluation in the Department of pathology, Community Based Medical College and a private laboratory during the period from January 2014 to December 2014. Mean age of the case was 32 years. Majority of the cases were female (126 out of 216)...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28256443/cat-scratch-disease-during-etanercept-therapy-in-a-rheumatoid-arthritis-patient
#15
Alberto O Orden, Norma N Nardi, Alicia B Vilaseca, Ana C Colombini, Nora G Barrios, Anahí Vijnovich Barón
Cat scratch disease (CSD) is an infectious disorder caused by Bartonella henselae and characterized by fever and granulomatous lymphadenopathy. Immunosuppression is a risk factor for the development of atypical forms of the disease. We report the case of a 52-year-old woman who presented with fever and bilateral inguinal lymph node enlargement. She did not have apparent contact with animals. The patient was receiving etanercept therapy for rheumatoid arthritis. Lymph node biopsy demonstrated granulomatous lymphadenitis...
February 27, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28255545/fatality-in-kikuchi-fujimoto-disease-a-rare-phenomenon
#16
Bianca Barbat, Ruby Jhaj, Daniyeh Khurram
Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is an uncommon condition, typically characterized by lymphadenopathy and fevers. It usually has a benign course; however, it may progress to fatality in extremely rare occasions. The diagnosis is made via lymph node biopsy and histopathology. Our patient was a young female who presented with shortness of breath, fever, and malaise. Physical examination revealed significant cervical and axillary lymphadenopathy. Chest X-ray displayed multilobar pneumonia...
February 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28252353/investigation-of-mycobacterium-avium-complex-mac-in-australian-commercial-milk-using-qpcr
#17
Shraddha Adhikari, Tanya Caro Tohme, Harriet Whiley
This technical research communication describes the first study to use quantitative polymerase chain reaction (qPCR) to investigate the presence of Mycobacterium avium complex (MAC) in Australian pasteurised milk. MAC is the most common NTM responsible for human illnesses and includes M. avium subspecies paratuberculosis (MAP). MAC is a causative agent of lymphadenitis in children, with contaminated food and water considered as a likely source. As such the presence of MAC in milk would have public health significance...
February 2017: Journal of Dairy Research
https://www.readbyqxmd.com/read/28249842/tb-lymphadenitis-is-associated-with-enhanced-baseline-and-antigen-specific-induction-of-type-1-and-type-17-cytokines-and-reduced-il-1%C3%AE-and-il-18-at-the-site-of-infection
#18
Gokul Raj Kathamuthu, Kadar Moideen, Dhanaraj Baskaran, Vaithilingam V Banurekha, Dina Nair, Gomathi Sekar, Rathinam Sridhar, Bharathi Vidyajayanthi, Ganeshan Gajendraraj, Dinesh Kumar Parandhaman, Alena Srinivasan, Subash Babu
Tuberculous lymphadenitis (TBL) is characterized by an expansion of Th1 and Th17 cells with altered serum levels of pro-inflammatory cytokines. However, the cytokine profile at the site of infection i.e. the affected lymph nodes, has not been examined in detail. To estimate the baseline and mycobacterial antigen - stimulated cytokine concentrations of Type 1, Type 17 and other pro-inflammatory cytokines in TBL, we examined both the baseline and the antigen - specific concentrations of these cytokines in TBL (n = 14) before and after chemotherapy and compared them with pulmonary tuberculosis infection (PTB, n = 14)...
March 1, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28197350/disseminated-mycobacterium-interjectum-infection-with-bacteremia-hepatic-and-pulmonary-involvement-associated-with-a-long-term-catheter-infection
#19
David Sotello, D Jane Hata, Mohammed Reza, Raj Satyanarayana, Vichaya Arunthari, Wendelyn Bosch
We present a 49-year-old female with one year of intermittent fevers, chills, night sweats, and significant weight loss. Liver and lung biopsy showed evidence of a granulomatous process. Blood and liver biopsy cultures yielded growth of presumed Mycobacterium interjectum, thought to be related to a disseminated long-term central venous catheter infection. She successfully received one year of combined antimicrobial therapy after catheter removal without recurrence of disease. M. interjectum has been previously described as a cause of lymphadenitis in healthy children and associated with pulmonary disease in adults, although other localized infections have been reported...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28195263/kikuchi-fujimoto-disease-a-clinicopathologic-update
#20
F Pepe, S Disma, C Teodoro, P Pepe, G Magro
Kikuchi-Fujmoto disease (KFD), also known as "histiocytic necrotizing lymphadenitis", is a rare lymphadenitis of unknown origin, but with an excellent prognosis. It is more common in Asia, but isolated cases are also reported in America, Africa and Europe. The disease can have an acute or subacute course, usually develops in 1 to 3 weeks, with spontaneous resolution in 1-4 months. The main clinical sign is cervical lymphadenopathy, especially in the posterior cervical triangle with bulky and painful lymph nodes, usually affecting only one side; rare cases of generalized lymphadenopathy can be seen...
September 2016: Pathologica
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