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https://www.readbyqxmd.com/read/29788907/mycobacterium-avium-complex-vertebral-osteomyelitis-in-the-absence-of-hiv-infection-a-case-report-and-review
#1
Megan E Gray, Peter W Liu, Brian Wispelwey
BACKGROUND: Mycobacterium Avium Complex (MAC) is an established microbiologic cause of pulmonary disease, lymphadenitis, and disseminated disease in cases of advanced immune suppression. However, MAC manifesting as vertebral osteomyelitis is less common, and is particularly rare in the absence of Acquired Immunodeficiency Syndrome (AIDS). Prompt diagnosis of MAC vertebral osteomyelitis is challenging, but necessary to prevent serious morbidity or mortality. CASE PRESENTATION: We report a case of MAC osteomyelitis of the lumbar spine in a 70-year-old woman on extended duration corticosteroid therapy for systemic lupus erythematosus who presented with progressive back pain...
May 22, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29785310/a-challenging-case-of-kikuchi-fujimoto-disease-associated-with-systemic-lupus-erythematosus-and-review-of-the-literature
#2
Mihaela Găman, Ana-Maria Vlădăreanu, Camelia Dobrea, Minodora Onisâi, Cristina Marinescu, Irina Voican, Daniela Vasile, Horia Bumbea, Diana Cîşleanu
Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare disease that is frequently underdiagnosed due to clinical features that are similar to those of non-Hodgkin lymphomas, systemic lupus erythematosus (SLE), or infectious reactive lymphadenopathy. An excisional biopsy is required. We report a young Caucasian female diagnosed with KFD with skin lesions, complicating with SLE. The clinical course, laboratory, and CT findings are described, as are histopathologic features, for a better recognition of this rare disorder in clinical practice...
2018: Case Reports in Hematology
https://www.readbyqxmd.com/read/29783260/-methods-of-diagnosis-of-non-specific-and-specific-lymphideniates-of-the-jaw-facial-part-in-children-literature-review
#3
Pavlo I Tkachenko, Yurii B Lobach, Sergii O Bilokon, Vitalina O Dobroskok, Yuliia V Popelo
OBJECTIVE: Introduction: Insufficient basic knowledge on the mechanisms of the multifactoral etiology and pathogenesis of various forms of maxillofacial lymphadenitis of odontogenic and non-odontogenic nature in children causes difficulties in making differential diagnosis. The algorithm of their examination involves a large number of methods, each of which has its own advantages and disadvantages with variable informativeness, depending on the particular situation. The aim: The paper is aimed atfamiliarization of broad medical public with informativeness of diagnostic measures in the nonspecific and specific affection of lymph nodes of the maxillofacial area in children...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783235/-statistical-information-about-the-inflammatory-processes-of-the-jaw-facial-part-in-children
#4
Pavlo I Tkachenko, Serhii O Bilokon, Nataliia M Lokhmatova, Vitalina O Dobroskok, Olha B Dolenko, Nataliia M Korotych, Yuliia V Popelo
OBJECTIVE: Introduction: The acute and chronic inflammatory processes prevail in the structure of the dental surgical diseases in children. Notably, various forms of lymphadenitis, adenophlegmon and odontogenous osteomyelitis dominate in the specialized surgical units; however, it is not possible to resolve a number of organizational problems without clear understanding of the statistical situation. The aim: The paper is aimed at the analysis of the incidence rate of major nosological forms of the acute suppurative inflammations of the maxillofacial area in children for the prospective planning of arrangements to provide them with high-quality specialized care...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29780717/robotic-internal-mammary-lymphadenectomy-another-possible-minimally-invasive-approach-to-sampling-lymph-nodes-in-breast-cancer-patients
#5
Alessandro Pardolesi, Luca Bertolaccini, Jury Brandolini, Piergiorgio Solli
Internal mammary lymphadenopathy may develop in breast cancer patients with silicone implants. Differential diagnosis includes malignant recurrence, infections, inflammations and granulomatous deposit. We report a case of internal mammary lymphadenopathy, in a patient with the previous history of breast cancer, requiring a tissue diagnosis. We performed a Robotic lymph nodes dissection of the left internal mammary. Final pathology diagnosis was positive for silicone granulomatous lymphadenitis secondary to silicone breast implants inserted after mastectomy for breast cancer...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29780242/immune-informatic-analysis-and-design-of-peptide-vaccine-from-multi-epitopes-against-corynebacterium-pseudotuberculosis
#6
Daniela Droppa-Almeida, Elton Franceschi, Francine Ferreira Padilha
Caseous lymphadenitis (CLA) is a disease caused by Corynebacterium pseudotuberculosis bacteria that affects sheep and goats. The absence of a serologic diagnose is a factor that contributes for the disease dissemination, and due to the formation of granuloma, the treatment is very expensive. Therefore, prophylaxis is the approach with best cost-benefit relation; however, it still lacks an effective vaccine. In this sense, this work seeks to apply bioinformatic tools to design an effective vaccine against CLA, using CP40 protein as standard for the design of immunodominant epitopes, from which a total of 6 sequences were obtained, varying from 10 to 16 amino acid residues...
2018: Bioinformatics and Biology Insights
https://www.readbyqxmd.com/read/29773279/-non-tuberculous-mycobacterial-cervical-adenitis-in-children-2-cases
#7
N Sigg, S Bailleul, J-M Turmel, G Legrand, S Kettani, L Martin
BACKGROUND: Cervical lymphadenitis is the most common manifestation of infection with nontuberculous mycobacteria (NTM) in immunocompetent children. Nevertheless, it is poorly known by dermatologists. Its incidence, which is currently increasing since the cessation of BCG vaccination in 2007, raises several issues regarding its pathophysiology, diagnosis and management. PATIENTS AND METHODS: We report two cases of NTM adenitis: one in a 2-year-old girl vaccinated with BCG and one in an unvaccinated 22-month-old boy, in whom a misleading presentation led to delayed diagnosis...
May 14, 2018: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29768565/cat-scratch-disease-presenting-as-axillary-lymphadenopathy-and-a-palpable-benign-mammary-nodule-mimicking-a-carcinoma
#8
Larissa Cabral Marques, Kátia Pincerato, Adriana Akemi Yoshimura, Felipe Eduardo Martins Andrade, Alfredo Carlos Simões Dornellas de Barros
We present a case involving a 74-year-old woman with cat scratch disease characterized by an enlarged and hard axillary lymph node as well as a palpable breast nodule mimicking a carcinoma. The lymph node and the breast nodule were excised. The pathologic examinations revealed granulomatous lymphadenitis with gram-negative bacilli and an intraductal papilloma. Antibiotic therapy (azithromycin) was prescribed and the patient's clinical evolution was excellent.
March 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29763927/reactive-lymphoid-hyperplasia-or-tubercular-lymphadenitis-can-real-time-pcr-on-fine-needle-aspirates-help-physicians-in-concluding-the-diagnosis
#9
Vivek Gupta, Arvind Bhake
BACKGROUND: Enlarged lymph nodes in adult patients often present a diagnostic challenge. In the absence of granuloma or necrosis, the cytology/tissue findings are misleading and relate the enlarged lymph nodes to reactive lymphoid hyperplasia (RLH), because granuloma formation is an immunological response that usually takes 14-100 days to develop. This study assesses the role of real-time (RT)-PCR in the diagnosis of the Mycobacterium complex (MTBC) in lymph node aspirates compared with culture in cases of RLH...
May 15, 2018: Acta Cytologica
https://www.readbyqxmd.com/read/29757583/what-immunological-defects-predispose-to-non-tuberculosis-mycobacterial-infections
#10
Esmaeil Mortaz, Milad Moloudizargari, Mohammad Varahram, Mehrnaz Movassaghi, Johan Garssen, Mehdi Kazempour Dizagie, Mehdi Mirsaeidi, Ian M Adcock
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil.  NTM cause a variety of diseases in humans that mainly affect the lung. A predisposition to pulmonary NTM is evident in patients with parenchymal structural diseases including bronchiectasis, emphysema, tuberculosis (TB), cystic fibrosis (CF), rheumatologic lung diseases and other chronic diseases with pulmonary manifestations. Lung infections are not the only consequences of being infected by NTM as they can also infect skin and soft tissue and may also cause lymphadenitis (predominantly in young children) and disseminated disease in human immunodeficiency virus (HIV)-infected patients or those with severely compromised immune system...
April 2018: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29756005/peripheral-lymph-node-excisional-biopsy-yield-relevance-and-outcomes-in-a-remote-surgical-setup
#11
Ashish Lal Shrestha, Pradita Shrestha
Objective: To study the patient profile for symptomatic peripheral lymphadenopathy in terms of histopathological findings and demography and evaluate the yield, relevance, and outcomes of peripheral lymph node biopsy (PLNB) as a diagnostic step in a remote setup in the absence of less invasive options like fine-needle aspiration cytology (FNAC) or ultrasonogram- (USG-) guided FNAC. Methods: A retrospective review of patients undergoing PLNB between 1 May 2011 and 30 April 2013 was done...
2018: Surgery Research and Practice
https://www.readbyqxmd.com/read/29755898/an-unusual-presentation-of-kikuchi-fujimoto-disease-with-recurrent-subdural-effusion
#12
Sara Shahid, Syed H Alam, Indira Hadley
A 24-year-old man complained of a right temporal headache for four weeks. The patient denied any trauma or previous anticoagulation use. He also reported tender right facial swelling. His physical exam was unrevealing except for right cranial nerve (CN) VI palsy, right parotid enlargement, and cervical adenopathy. Laboratory findings were significant for mild leukopenia at 3300 cells/uL. The computed tomography (CT) scan obtained showed a chronic left subdural effusion with a 4 mm midline shift and confirmed right parotid enlargement and cervical lymphadenopathy...
March 10, 2018: Curēus
https://www.readbyqxmd.com/read/29754963/predictors-of-a-drainable-suppurative-adenitis-among-children-presenting-with-cervical-adenopathy
#13
Amir A Kimia, Tiffany F Rudloe, Nadine Aprahamian, Jennifer McNamara, David Roberson, Assaf Landschaft, Jennifer Vaughn, Marvin B Harper
OBJECTIVES: We sought to identify predictors for a drainable suppurative adenitis [DSA] among patients presenting with acute cervical lymphadenitis. METHODS: A retrospective cross sectional study of all patients admitted to an urban pediatric tertiary care emergency department over a 15 year period. Otherwise healthy patients who underwent imaging for an evaluation of cervical lymphadenitis were included. Cases were identified using a text-search module followed by manual review...
May 5, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29742650/murine-typhus-mimicking-kawasaki-disease-in-a-pre-adolescent-girl
#14
Maria A Karalexi, Marina Mitrogiorgou, Erato Atsali, Antonios Theodorakopoulos, Achilleas Attilakos, Vasileios Tsagris
We report the case of an 11-year-old pre-adolescent girl presenting with prolonged fever, lymphadenitis, non-purulent conjuctivitis, a generalized maculopapular rash, erythematous lips and edema of hands/feet. Although major diagnostic criteria for Kawasaki disease were met, local epidemiologic data suggested a possible vector-borne etiology. Treatment with doxycycline was initiated and defervescence occurred. Laboratory investigation confirmed the diagnosis of Rikettsia typhi infection.
May 4, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29742144/mpt64-antigen-detection-test-improves-routine-diagnosis-of-extrapulmonary-tuberculosis-in-a-low-resource-setting-a-study-from-the-tertiary-care-hospital-in-zanzibar
#15
Melissa Davidsen Jørstad, Msafiri Marijani, Anne Ma Dyrhol-Riise, Lisbet Sviland, Tehmina Mustafa
BACKGROUND: Extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. An immunochemistry-based MPT64 antigen detection test (MPT64 test) has reported higher sensitivity in the diagnosis of EPTB compared with conventional methods. The objective of this study was to implement and evaluate the MPT64 test in routine diagnostics in a low-resource setting. METHODS: Patients with presumptive EPTB were prospectively enrolled at Mnazi Mmoja Hospital, Zanzibar, and followed to the end of treatment...
2018: PloS One
https://www.readbyqxmd.com/read/29742052/clinical-and-drug-resistance-characteristics-of-new-pediatric-tuberculosis-cases-in-northern-china
#16
Ting Wang, Fang Dong, Qin-Jing Li, Qing-Qin Yin, Wen-Qi Song, Igor Mokrousov, Wei-Wei Jiao, A-Dong Shen
AIM: The aim of this study was to evaluate the clinical features and characteristics of drug resistance in newly diagnosed pediatric tuberculosis (TB) patients in northern China. METHODS: Mycobacterium tuberculosis isolates were collected from September 2010 to October 2016 at the Beijing Children's Hospital. Patients were divided into two groups (resistant to at least one drug and pan-susceptible) according to drug susceptibility testing (DST) results. RESULTS: A total of 132 new cases, mainly from northern China (87...
May 9, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29735847/acute-hepatitis-due-to-epstein-barr-virus-with-cross-reacting-antibodies-to-cytomegalovirus
#17
Asli Karadeniz, Zuhal Yesilbag, Fatih Öner Kaya, Feride Sinem Akgün
Epstein-Barr virus (EBV) is the cause of systemic infection known as infectious mononucleosis with classic presentation of fever, oropharyngitis and lymphadenitis. EBV rarely causes acute hepatitis. In this report, we present a 19-year-old patient presented with nausea, fatigue and jaundice. Her physical examination and laboratory tests revealed the diagnosis as acute hepatitis due to EBV with cross-reacting antibodies to cytomegalovirus.
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29731568/toxoplasmosis-submandibular-lymphadenitis-report-of-an-unusual-case-with-a-brief-review
#18
Susmita Saxena, Sanjeev Kumar, Jitin Kharbanda
A 16-year-old male patient reported with swelling of the right submandibular region for 3 months. The patient was asymptomatic and gave a history of fever lasting for 2 days before observing the swelling. Fine-needle aspiration cytology revealed nonspecific lymphadenitis, and since there was no apparent cause detected in the oral cavity or any systemic condition noted, the enlarged lymph node was surgically excised and submitted for histopathologic examination. The inflammatory condition and large numbers of macrophages appeared nonspecific while granuloma formation was not seen...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29728170/pediatric-lateral-neck-infections-computed-tomography-vs-ultrasound-on-initial-evaluation
#19
Nicholas A Quinn, Jared A Olson, Jeremy D Meier, Hank Baskin, Jeff E Schunk, Emily A Thorell, Laura N Hodo
OBJECTIVE: Review the evaluation of children with a deep lateral neck infection and define the impact of initial imaging modality on outcomes and costs. METHOD: Case series, pediatric patients <18 years of age admitted to a tertiary care hospital with lateral neck infection between 01/01/14-05/31/16 as identified by ICD-9 and ICD-10 codes: 289.3 (lymphadenitis, unspecified), 682.1 (cellulitis and abscess of neck), 683 (acute lymphadenitis), I88.9 (nonspecific lymphadenitis, unspecified), L02...
June 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29709375/purulent-lymphadenitis-caused-by-staphylococcus-argenteus-representing-the-first-japanese-case-of-staphylococcus-argenteus-multilocus-sequence-type-2250-infection-in-a-12-year-old-boy
#20
Takuma Ohnishi, Masayoshi Shinjoh, Hirotoshi Ohara, Toshinao Kawai, Isamu Kamimaki, Ryo Mizushima, Keisuke Kamada, Yasutomo Itakura, Shigekazu Iguchi, Yutaka Uzawa, Atsushi Yoshida, Ken Kikuchi
Staphylococcus argenteus is a novel species separated from a strain of coagulase-positive, non-pigmented S. aureus. Although S. argenteus has been reported to occur globally, multilocus sequence type (ST) 2250 is mainly found in Northeastern Thailand. Because conventional biochemical testing misidentifies this pathogen as S. aureus, multilocus sequence typing (MLST) or nucA sequencing is recommended to distinguish between S. argenteus and S. auereus. The patient was a previously healthy 12-year-old boy who was admitted because of right inguinal lymphadenitis and cellulitis...
April 27, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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