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https://www.readbyqxmd.com/read/28096860/determination-of-asymptomatic-malaria-among-afghani-and-pakistani-immigrants-and-native-population-in-south-of-kerman-province-iran
#1
Mohammad Bagher Amirshekari, Mehdi Nateghpour, Ahmad Raeisi, Afsaneh Motevalli Haghi, Leila Farivar, Gholamhosein Edrissian
BACKGROUND: This study was proposed to monitor the situation of asymptomatic malaria among the native population and Afghani and Pakistani immigrants in Kahnooj and Ghale-Ganj districts from Kerman Province, Southeastern Iran. METHODS: A number of 180 and 120 individuals from Kahnooj and Ghale-Ganj respectively were registered and considered based on a cross-sectional surveillance method. From 300 registered cases, 200 individuals (66.7%) were selected among Afghani and Pakistani immigrants and the rest (33...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28071616/presenting-features-treatment-patterns-and-outcomes-of-patients-with-breast-cancer-in-pakistan-experience-at-a-university-hospital
#2
S Kumar, A J Shaikh, Y A Rashid, N Masood, Atv Mohammed, U Z Malik, G Haider, N Niamutullah, S Khan
BACKGROUND: Breast cancer is the most common cancer in Pakistani women. We report the presenting features, treatment patterns and survival of breast cancer from a University Hospital in Southern Pakistan and compare the data with international population based studies. MATERIALS AND METHODS: Medical records of patients diagnosed to have breast cancer between January 1999 and November 2008 were reviewed retrospectively. RESULTS: A total of 845 patients were identified...
April 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28068537/the-immigrant-paradox-on-internalizing-symptoms-among-immigrant-adolescents
#3
Anica G Bowe
Understanding the immigrant paradox on health outcomes among UK's immigrant adolescents will greatly complement the research on immigrants that has already been established there by economists and interdisciplinary fields. This study used the first Longitudinal Study of Young People in England 2004-2010 database (N = 15,770) to determine a) whether there was evidence of the immigrant paradox on internalizing mental health symptoms between first generation (n = 753) and second plus generation (n = 3042) 14/15 year old immigrant adolescents in England and b) whether differences (if any) were moderated by ethnicity group membership (Black African, Black Caribbean, Indian, Pakistani, Bangladeshi, Asian Other, White Immigrant)...
January 6, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28052948/tb-or-not-to-be-kikuchi-fujimoto-disease-a-rare-but-important-differential-for-tb
#4
C McKenna, T Whitfield, N Patel, A Bonington
A 29-year-old British Pakistani woman presented with a 2-month history of drenching fevers, night sweats, lethargy and tender cervical and axillary lymphadenopathy. Initial investigations, bloods and imaging were unremarkable. Fever persisted during her admission, and treatment for tuberculosis (TB) lymphadenitis was started postbiopsy until histology confirmed a diagnosis of Kikuchi-Fujimoto's disease (KFD). KFD has a non-specific presentation of fever, night sweats and lymphadenopathy and commonly raises a clinical suspicion of a number of other serious conditions such as TB, lymphoma, HIV, systemic lupus erythematous, toxoplasmosis and infectious mononucleosis...
January 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28050747/the-association-between-muslim-religiosity-and-young-adult-college-students-depression-anxiety-and-stress
#5
Mohammad Nadeem, Akhtar Ali, Muhammad Ayub Buzdar
Depression, anxiety, and stress are among major psychological disorders being predominant in present day. This study proposed to analyze the role of Muslim religiosity in male students showing these mental indications. A sample including 723 Pakistani young adults enrolled at college level was randomly chosen. Muslim Religiosity Measurement Scale and Depression, Anxiety and Stress Scale were utilized to gather information. Discoveries uncover an inverse relationship between conduct and affiliation with the symptoms of mental disorders, anxiety and stress among the respondents...
January 3, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28043630/effective-testing-for-pulmonary-tuberculosis-using-xpert-mtb-rif-assay-for-stool-specimens-in-immunocompetent-pakistani-children
#6
Zahra Hasan, Fehmina Arif, Sadia Shakoor, Aisha Mehnaz, Alnoor Akber, Akbar Kanji, Mussarat Ashraf, Rumina Hasan
OBJECTIVE/BACKGROUND: Childhood tuberculosis (TB) is largely a paucibacillary disease and difficult to diagnose. It is difficult to obtain a sputum or gastric aspirate (GA) sample, and patients are often undiagnosed and treated empirically. Stool is a noninvasive specimen not usually used for TB testing in Pakistan. We investigated the value of Xpert MTB/RIF to diagnose Mycobacterium tuberculosis (MTB) in children with pulmonary TB cases, by performing comparative testing of GA and stool samples...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043516/evaluation-of-genotype-mtbdrplus-assay-for-rapid-detection-of-isoniazid-and-rifampicin-resistance-in-mycobacterium-tuberculosis-clinical-isolates-from-pakistan
#7
Hasnain Javed, Nazia Jamil, Tomasz Jagielski, Zofia Bakuła, Zarfishan Tahir
BACKGROUND: GenoType MTBDRplus is a molecular assay for detection of Mycobacterium tuberculosis resistance to isoniazid (INH) and rifampicin (RMP), the two major anti-tuberculosis (TB) drugs. Identification of INH resistance is largely based on the occurrence of mutations in the katG gene, coding for the catalase-peroxidase, or in the promoter region of the inhA gene, coding for the NADH-dependent enoyl-ACP reductase. For testing the RMP resistance, mutations in the rpoB gene, coding for the RNA polymerase β subunit, particularly in the RMP resistance determining region (RRDR) of the gene are investigated...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28031839/a-massive-pleural-based-desmoid-tumour
#8
Talha Mahmud, Guness Mal, Farhan Ahmed Majeed, Siaw Ming Chai, Y C Gary Lee
A 49-year-old Pakistani male presented with "heaviness" in his chest. Chest radiograph and computed tomography (CT) confirmed a massive left-sided pleural-based opacity. Three years ago, he was investigated for a left-sided lymphocytic, exudative pleural effusion following an episode of dengue fever. Tube thoracostomy removed 1.3 L of fluid. Pleural biopsy and bronchial washings were non-contributory. He received empirical anti-tuberculosis treatment and remained asymptomatic until this presentation. To investigate the new pleural mass, he underwent a video-assisted thoracoscopic surgery, which revealed a 2...
January 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28028295/current-trends-of-seroprevalence-of-transfusion-transmitted-infections-in-pakistani-%C3%AE-thalassaemic-patients
#9
S Sultan, S M Irfan, M Siddiqui, S M H Zaidi
BACKGROUND: Though regular blood transfusion improves the survival, it carries the unavoidable risk of transfusion transmitted infections (TTI) in β-thalassaemic patients. Owing to the lack of uniformity in blood screening practices in Pakistan, TTI is still a major challenge. OBJECTIVES: To study the current trends of TTI in regularly transfused β-thalassaemics and their correlation with age, number of transfusions, hematological and biochemical markers. METHODS: We carried out a prospective case-control study...
December 2016: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28004384/genetic-heterogeneity-in-pakistani-microcephaly-families-revisited
#10
I Ahmad, S M Baig, A R Abdulkareem, M S Hussain, I Sur, M R Toliat, G Nürnberg, N Dalibor, A Moawia, S S Waseem, M Asif, H Nagra, M Sher, M M Ali Khan, I Hassan, S Ur Rehman, H Thiele, J Altmüller, A A Noegel, P Nürnberg
Autosomal recessive primary microcephaly (MCPH) is a rare and heterogeneous genetic disorder characterized by reduced head circumference, low cognitive prowess and, in general, architecturally normal brains. As many as 14 different loci have already been mapped. We recruited 35 MCPH families in Pakistan and could identify the genetic cause of the disease in 31 of them. Using homozygosity mapping complemented with whole-exome, gene panel or Sanger sequencing, we identified twelve novel mutations in three known MCPH-associated genes - nine in ASPM, two in MCPH1 and one in CDK5RAP2...
December 22, 2016: Clinical Genetics
https://www.readbyqxmd.com/read/27999155/ethnic-differences-in-longitudinal-latent-verbal-profiles-in-the-millennium-cohort-study
#11
Afshin Zilanawala, Yvonne Kelly, Amanda Sacker
BACKGROUND: Development of verbal skills during early childhood and school age years is consequential for children's educational achievement and adult outcomes. We examine ethnic differences in longitudinal latent verbal profiles and assess the contribution of family process and family resource factors to observed differences. METHODS: Using data from the UK Millennium Cohort Study and the latent profile analysis, we estimate longitudinal latent verbal profiles using verbal skills measured 4 times from age 3-11 years...
December 2016: European Journal of Public Health
https://www.readbyqxmd.com/read/27979836/longitudinal-study-of-cardiometabolic-risk-from-early-adolescence-to-early-adulthood-in-an-ethnically-diverse-cohort
#12
Seeromanie Harding, Maria João Silva, Oarabile R Molaodi, Zinat E Enayat, Aidan Cassidy, Alexis Karamanos, Ursula M Read, J Kennedy Cruickshank
OBJECTIVE: To examine influences of adiposity from early adolescence to early 20s on cardiovascular disease (CVD) risk in the multiethnic Determinants of young Adult Social well-being and Health (DASH) longitudinal study. METHODS: In 2002-2003, 6643 11-13-year-olds from 51 London schools participated at baseline, and 4785 were seen again at 14-16 years. Recently, 665 (97% of invited) participated in pilot follow-up at 21-23 years, with biological and psychosocial measures and blood biomarkers (only at 21-23 years)...
December 14, 2016: BMJ Open
https://www.readbyqxmd.com/read/27977575/a-systematic-review-of-treatment-response-rates-in-pakistani-hepatitis-c-virus-patients-current-prospects-and-future-challenges
#13
Muhammad Ali, Samia Afzal, Asad Zia, Ahmed Hassan, Ali Talha Khalil, Muhammad Ovais, Zabta Khan Shinwari, Muhammad Idrees
BACKGROUND: The estimated hepatitis C virus (HCV) carriers are approximately 10 million in Pakistan which usually progresses to chronic hepatitis, with rare cases of spontaneous viral eradication. The present article reviews the treatment status of HCV infection in Pakistani population and various factors associated with the treatment response rates. METHODS: Literature on anti-HCV therapy was searched in PubMed, Google Scholar and PakMediNet. Thirty three different studies representing different geographic regions of Pakistan published from 2002 to 2016 were included in the present review...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27973692/type-2-diabetes-mellitus-in-people-with-severe-mental-illness-inequalities-by-ethnicity-and-age-cross-sectional-analysis-of-588-408-records-from-the-uk
#14
J Das-Munshi, M Ashworth, M E Dewey, F Gaughran, S Hull, C Morgan, J Nazroo, I Petersen, P Schofield, R Stewart, G Thornicroft, M J Prince
AIMS: To investigate whether the association of severe mental illness with Type 2 diabetes varies by ethnicity and age. METHODS: We conducted a cross-sectional analysis of data from an ethnically diverse sample of 588 408 individuals aged ≥18 years, registered to 98% of general practices (primary care) in London, UK. The outcome of interest was prevalent Type 2 diabetes. RESULTS: Relative to people without severe mental illness, the relative risk of Type 2 diabetes in people with severe mental illness was greatest in the youngest age groups...
December 14, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27971981/assessment-of-awareness-and-knowledge-of-breast-cancer-in-pakistani-females-a-quantitative-study
#15
S Azhar, N Saeed, S Khalida, A Bukhari, H Saeed, A Syed
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27965865/cultural-adaptation-of-a-children-s-weight-management-programme-for-bangladeshi-and-pakistani-families-in-the-uk-a-cluster-randomised-feasibility-study-protocol
#16
Miranda Pallan, Tania Griffin, Emma Lancashire, Kiya Hurley, Jacqueline Blissett, Emma Frew, Paramjit Gill, Laura Griffith, Karla Hemming, Kate Jolly, Eleanor McGee, Charlene Mulhern, Jayne Parry, Janice L Thompson, Peymane Adab
BACKGROUND: Group-based children's weight management programmes are widely available in the UK and evidence shows that these are effective in the short-term. No programmes have been specifically developed to meet the cultural requirements of UK minority ethnic communities. South Asian children are a high-risk group for obesity and its consequences; therefore, the study aim is to adapt an existing weight management programme for children aged 4-11 years and their families to ensure cultural relevance to Pakistani and Bangladeshi communities, and undertake a feasibility study of the adapted programme...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27965375/recessive-progressive-symmetric-erythrokeratoderma-results-from-a-homozygous-loss-of-function-mutation-of-krt83-and-is-allelic-with-dominant-monilethrix
#17
Khadim Shah, Muhammad Ansar, Zaib-Un-Nisa Mughal, Falak Sher Khan, Wasim Ahmad, Tracey M Ferrara, Richard A Spritz
BACKGROUND: Progressive symmetric erythrokeratoderma (PSEK) is a rare skin disorder characterised by symmetrically distributed demarcated hyperkeratotic plaques, often with associated palmoplantar hyperkeratosis, with new plaques appearing over time. Most cases are inherited in an autosomal dominant manner, although a few cases exhibit apparent autosomal recessive inheritance. OBJECTIVE: To identify the gene underlying autosomal recessive PSEK in a large Pakistani kindred...
December 13, 2016: Journal of Medical Genetics
https://www.readbyqxmd.com/read/27955688/the-respite-trial-remifentanil-intravenously-administered-patient-controlled-analgesia-pca-versus-pethidine-intramuscular-injection-for-pain-relief-in-labour-study-protocol-for-a-randomised-controlled-trial
#18
Matthew Wilson, Christine MacArthur, Fang Gao Smith, Leanne Homer, Kelly Handley, Jane Daniels
BACKGROUND: The commonest opioid used for pain relief in labour is pethidine (meperidine); however, its effectiveness has long been challenged and the drug has known side effects including maternal sedation, nausea and potential transfer across the placenta to the foetus. Over a third of women receiving pethidine require an epidural due to inadequate pain relief. Epidural analgesia increases the risk of an instrumental vaginal delivery and its associated effects. Therefore, there is a clear need for a safe, effective, alternative analgesic to pethidine...
December 12, 2016: Trials
https://www.readbyqxmd.com/read/27939419/traditional-medicine-among-people-of-pakistani-descent-in-the-capital-region-of-copenhagen
#19
Sara Ramzan, Jens Soelberg, Anna K Jäger, Lourdes Cantarero-Arévalo
ETHNOPHARMACOLOGICAL RELEVANCE: Studies show that ethnic minorities continue to use their cultural traditional medicines also after migration to the West. Research in this field is necessary, given that little is known about traditional medicines' impact on health-related problems. This study sheds light on the issue through a qualitative study among ethnic Pakistanis residing in Denmark. AIM OF THE STUDY: The study addresses perception, knowledge and attitudes regarding the use of medicinal plants among Pakistanis living in Copenhagen...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27929723/prevalence-and-risk-factors-of-strabismus-in-a-uk-multi-ethnic-birth-cohort
#20
Alison Bruce, Gillian Santorelli
PURPOSE: To determine the prevalence, types and early-life risk factors associated with strabismus in a multi-ethnic birth cohort of children aged 4-5 years in the first year of school. METHODS: Data were collected prospectively over a 3-year period (2012-2015) from children participating in the vision screening program provided by orthoptists and carried out in schools located in the city of Bradford, UK. Prevalence of strabismus was determined for 17,018 children aged 4 to 5 years...
December 2016: Strabismus
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