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Viscosupplementation

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https://www.readbyqxmd.com/read/28128473/obesity-and-radiological-severity-are-associated-with-viscosupplementation-failure-in-patients-with-knee-osteoarthritis
#1
Florent Eymard, Xavier Chevalier, Thierry Conrozier
Viscosupplementation (VS) is still controversial. One of the key points is the lack of well-identified factors of response. We aimed to identify clinical and radiological factors associated with lack of relevant response after intra-articular (IA) hyaluronic acid (HA) injections in symptomatic knee osteoarthritis patients. A post hoc analysis of the HAV-2012 trial, a controlled, multicentre, double-blind, randomized, non-inferiority trial comparing 3 weekly IA injections of HA (HAnox-M or BioHA) for symptomatic tibiofemoral OA was performed...
January 27, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28117254/prospective-evaluation-of-intra-articular-sodium-hyaluronate-injection-in-the-ankle
#2
Evelyn P Murphy, Mark Curtin, Niall P McGoldrick, Gerard Thong, Stephen R Kearns
Viscosupplementation by injection of hyaluronic acid into the ankle can be used to provide pain relief and to delay the need for surgery in patients with osteoarthritis of the ankle. In the present investigation, we prospectively evaluated 50 consecutive patients (25 males and 25 females) undergoing a 3-injection protocol of sodium hyaluronate viscosupplementation in the ankle from January 2014 to January 2015. The Foot and Ankle Outcomes Score was used to compare the patients' pre- and post-treatment opinions about their ankle problems...
January 20, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28092250/-osteoarthrosis-implementation-of-current-diagnostic-and-therapeutic-algorithms
#3
Gilberto Meza-Reyes, Jorge Aldrete-Velasco, Rolando Espinosa-Morales, Fernando Torres-Roldán, Alejandro Díaz-Borjón, Manuel Robles-San Román
In the modern world, among the different clinical presentations of osteoarthritis, gonarthrosis and coxarthrosis exhibit the highest prevalence. In this paper, the characteristics of osteoarthritis and the different scales of assessment and classification of this pathology are exposed, to provide an exhibition of current evidence generated around diagnostic algorithms and treatment of osteoarthritis, with emphasis set out in the knee and hip, as these are the most frequent; a rational procedure for monitoring patients with osteoarthritis based on characteristic symptoms and the severity of the condition is also set...
January 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28066733/viscosupplementation-with-intra-articular-hyaluronic-acid-for-hip-disorders-a-systematic-review-and-meta-analysis
#4
Eleonora Piccirilli, Francesco Oliva, Mihaela Aconstantinesei Murè, Asmaa Mahmoud, Calogero Foti, Umberto Tarantino, Nicola Maffulli
BACKGROUND: Hip joint diseases are common in adult population and their prevalence increases with age. Osteoarthritis, rheumatoid arthritis and femoroacetabular impingement are the most common chronic diseases in the hip joint. Viscosupplementation with exogenous hyaluronic acid (HA) is one of the most widely used conservative treatment aiming to improve synovial fluid properties and to decrease pain. There is no global consensus on the type of HA, method of injection and frequency, or on its efficacy in hip joint...
July 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28056915/predictors-of-response-to-viscosupplementation-in-patients-with-hip-osteoarthritis-results-of-a-prospective-observational-multicentre-open-label-pilot-study
#5
Florent Eymard, Bernard Maillet, Henri Lellouche, Sylvie Mellac-Ducamp, Olivier Brocq, Damien Loeuille, Xavier Chevalier, Thierry Conrozier
BACKGROUND: To identify predictive factors of response to viscosupplementation (VS) in patients with hip osteoarthritis (HOA). METHODS: Prospective, multicentre, open-label trial, achieved in daily practice conditions. Patients with HOA were treated with a single intra-articular injection of a cross-linked hyaluronic acid combined with mannitol (HAnox-M-XL), using imaging guidance. WOMAC pain and function scores and patient global assessment (PGA) were assessed at baseline and day 90...
January 6, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28002896/comparing-hybrid-hyaluronic-acid-with-prp-in-end-career-athletes-with-degenerative-cartilage-lesions-of-the-knee
#6
R Papalia, B Zampogna, F Russo, S Vasta, M C Tirindelli, C Nobile, A C Di Martino, G Vadalà, V Denaro
Cartilage lesions are very common causes of chronic knee pain in athletes. Current treatment options consist in conservative strategies, such as viscosupplementation and platelet-rich plasma injections. This randomized controlled trial aims to investigate the effect of intra-articular Hybrid Hyaluronic Acid injections compared to PRP for the treatment of cartilage lesions among athletes at the end of their career. Since March 2015, 48 professional soccer players were randomized into two groups: 24 patients received 3 injections of HHA and 23 patients received 3 intra-articular injections of PRP...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27920810/hyaluronic-acid-in-the-management-of-osteoarthritis-injection-therapies-innovations
#7
Valter Santilli, Marco Paoloni, Massimiliano Mangone, Federica Alviti, Andrea Bernetti
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by pain and progressive functional limitation. Viscosupplementation with intra-articular (IA) hyaluronic acid (HA) could be a treatment option in OA, however recommendations made in different international guidelines for the non-surgical management of OA are not always concordant with regard to the role of IA injection therapies. Results from a recent Italian Consensus Conference underline how IA-HA to treat OA represents a widely used therapy in Italy...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27895439/comparison-of-two-different-molecular-weight-intra-articular-injections-of-hyaluronic-acid-for-the-treatment-of-knee-osteoarthritis
#8
I Gigis, E Fotiadis, A Nenopoulos, K Tsitas, I Hatzokos
BACKGROUND: Knee osteoarthritis (OA) is an incurable joint disorder, representing a major public health issue. Among options for symptom control, viscosupplementation with hyaluronic acid (HA) had established usefulness in pain and function improvement of the knee. However, it is not clear which form of HA yields better results. MATERIAL AND METHODS: We compared two HA preparations with high (HMW) or low molecular weight (LMW) in terms of pain control and function improvement using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the visual analog scale (VAS) score in patients with knee OA...
January 2016: Hippokratia
https://www.readbyqxmd.com/read/27891055/imaging-guidance-improves-the-results-of-viscosupplementation-with-hanox-m-xl-in-patients-with-ankle-osteoarthritis-results-of-a-clinical-survey-in-50-patients-treated-in-daily-practice
#9
Marie Bossert, Daniel Boublil, Jean-Marc Parisaux, Ana-Maria Bozgan, Emmanuel Richelme, Thierry Conrozier
BACKGROUND: The objective of this survey was to assess retrospectively the interest of performing viscosupplementation using imaging guidance in patients suffering from ankle osteoarthritis (OA). PATIENTS AND METHODS: This is a multicenter retrospective survey using a standardized questionnaire. Fifty patients suffering from ankle OA and treated, in daily clinical practice, with a single intra-articular injection of a novel viscosupplement made of a combination of a non-animal cross-linked hyaluronan and mannitol, HANOX M-XL, were included in the survey...
2016: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27860135/joint-lavage-followed-by-viscosupplementation-and-triamcinolone-in-patients-with-severe-haemophilic-arthropathy-objective-functional-results
#10
M U Rezende, F R Andrusaitis, R T Silva, E Okazaki, J D A Carneiro, G C Campos, A F Pailo, R Frucchi, T Pasqualin, P R Villaça
INTRODUCTION: Viscosupplementation can improve function in haemophilia patients. Viscosupplementation results can be improved by prior joint lavage and triamcinolone administration. AIM: To objectively assess whether viscosupplementation and associated triamcinolone use in patients with severe haemophilic arthropathy following joint lavage improves force and balance and reduces bleeding events. METHODS: Fourteen patients with haemophilic knee arthritis with and without the involvement of other joints underwent joint lavage and subsequent injections of Hylan G-F20 and triamcinolone into all affected joints...
November 16, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27848271/improvement-in-condition-specific-and-generic-quality-of-life-outcomes-in-patients-with-knee-osteoarthritis-following-single-injection-synvisc-results-from-the-lobras-study
#11
P Kearey, A E Popple, J Warren, T Davis, N Bellamy, For The Lobras Study Group
OBJECTIVE: To evaluate the effectiveness of viscosupplementation with single-injection hylan G-F20 (Synvisc-One) in knee osteoarthritis (OA), during routine clinical care, in a 52 week observational study. RESEARCH DESIGN AND METHODS: The LOBRAS study involved a 1 year long, multi-center, quasi-experimental, repeated measures, observational study. Consenting patients in Australia fulfilling inclusion/exclusion criteria under the care of a medical specialist in routine clinical practice were enrolled...
December 16, 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/27822391/ultrasound-guided-genicular-nerve-thermal-radiofrequency-ablation-for-chronic-knee-pain
#12
Joshua Wong, Nicholas Bremer, Paul D Weyker, Christopher A J Webb
Osteoarthritis (OA) of the knee is one of the most common joint diseases affecting adults in the United States. For elderly patients with multiple medical comorbidities who do not wish to undergo total knee arthroplasty (TKA), lifestyle modification, pharmacologic management, and injections are the mainstay of therapy. Previously, pain management interventions were limited to intra-articular joint injections and viscosupplementation with hyaluronic acid. Fluoroscopic-guided techniques for radiofrequency ablation (RFA) of the genicular nerves have been previously described and a recent cadaveric study suggests that ultrasound-guided genicular nerve blocks can be performed accurately...
2016: Case Reports in Anesthesiology
https://www.readbyqxmd.com/read/27814744/hyaluronic-acid-injection-therapy-for-osteoarthritis-of-the-knee-concordant-efficacy-and-conflicting-serious-adverse-events-in-two-systematic-reviews
#13
Claire E O'Hanlon, Sydne J Newberry, Marika Booth, Sean Grant, Aneesa Motala, Margaret A Maglione, John D FitzGerald, Paul G Shekelle
BACKGROUND: The prevalence of knee osteoarthritis (OA)/degenerative joint disease (DJD) is increasing in the USA. Systematic reviews of treatment efficacy and adverse events (AEs) of hyaluronic acid (HA) injections report conflicting evidence about the balance of benefits and harms. We review evidence on efficacy and AEs of intraarticular viscosupplementation with HA in older individuals with knee osteoarthritis and account for differences in these conclusions from another systematic review...
November 4, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27757290/bipartite-patella-in-35-year-old-fitness-instructor-a-case-report
#14
Sebastian Zabierek, Jakub Zabierek, Adam Kwapisz, Marcin E Domzalski
BACKGROUND AND PURPOSE: The patella plays an important role in knee biomechanics and provides anterior coverage of the knee joint. One to two percent of the population has an anatomical variant of patella called a bipartite patella that usually does not case pain. However, occasionally after injury or overuse during sport it can be a source of anterior knee pain. The purpose of this case report was to present a rare variant of bipartite patella and highlight conservative treatment of this condition...
October 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27681813/clinical-comparison-of-oral-administration-and-viscosupplementation-of-hyaluronic-acid-ha-in-early-knee-osteoarthritis
#15
M Ricci, G M Micheloni, M Berti, F Perusi, E Sambugaro, E Vecchini, B Magnan
PURPOSE: Osteoarthritis (OA) is a progressive, chronic and degenerative joint disease characterized by a loss of articular cartilage. Treatment of OA is largely palliative based on nonsteroidal anti-inflammatory drugs, opioids and injections of steroids. Regarding conservative treatment, intra-articular injections of hyaluronic acid (HA) can play a role in early symptomatic knee OA. MATERIALS AND METHODS: Between August 2015 and September 2015, sixty patients (32 males and 28 females) between 40 and 70 years old were randomly allocated into two groups: Half were treated with three weekly intra-articular injections of hyaluronic acid 1...
September 28, 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27672901/poster-133-analysis-of-pain-and-functionality-in-knee-osteoarthritis-patients-after-sodium-hyaluronate-viscosupplementation
#16
Erika M Suzigan, Eduardo E Rocha, Cyro Scala
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27660427/clinical-effectiveness-in-severe-knee-osteoarthritis-after-intra-articular-platelet-rich-plasma-therapy-in-association-with-hyaluronic-acid-injection-three-case-reports
#17
Szu-Hsuan Chen, Ta-Shen Kuan, Mu-Jung Kao, Wei-Ting Wu, Li-Wei Chou
Osteoarthritis (OA) is a degenerative disorder resulting from loss of joint cartilage and underlying bone and causes pain and loss of function. The treatment of knee OA is still a challenge because of the poor self-regeneration capacity of cartilage. The nonsurgical interventions include control of the aggravating factor (such as weight control and the use of walking aids), symptomatic treatment (such as acetaminophen or nonsteroidal anti-inflammatory drugs), prolotherapy, and viscosupplementation. However, the combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) has not been widely used because of lack of clinical evidence and several limitations in patients with severe knee OA...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27638344/interrelationship-between-temporomandibular-joint-osteoarthritis-oa-and-cervical-spine-pain-effects-of-intra-articular-injection-with-hyaluronic-acid
#18
Luca Guarda-Nardini, Cristina Cadorin, Antonio Frizziero, Stefano Masiero, Daniele Manfredini
OBJECTIVE: The aim of this study was to evaluate cervical spine pain and function after five sessions of viscosupplementation with hyaluronic acid (HA) in patients with temporomandibular joint (TMJ) osteoarthritis. METHODS: Forty-nine patients, (79% females, aged between 43-81 years), affected by TMJ osteoarthritis and concurrent cervical spine pain and limited function were recruited. All patients underwent a cycle of five weekly arthrocenteses and viscosupplementation with 1 ml of medium molecular weight HA according to the single-needle arthrocentesis technique...
September 16, 2016: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/27574261/microfracture-technique-versus-carbon-fibre-rod-implantation-for-treatment-of-knee-articular-cartilage-lesions
#19
U Dasar, S Gursoy, M Akkaya, O Algin, C Isik, M Bozkurt
PURPOSE: To compare the microfracture technique with carbon fibre rod implantation for treatment of knee articular cartilage lesions. METHODS: 10 men and 30 women aged 22 to 56 (mean, 37.4) years underwent microfracture (n=20) or carbon fibre rod implantation (n=20) for International Cartilage Repair Society grade 3 to 4 knee articular cartilage lesions after a mean of 12.2 months of viscosupplementation and physiotherapy. Clinical outcome at 6 and 12 months was assessed using the Tegner-Lysholm score and modified Cincinnati score...
August 2016: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/27528611/no-effects-of-early-viscosupplementation-after-arthroscopic-partial-meniscectomy-a-randomized-controlled-trial
#20
Giuseppe Filardo, Berardo Di Matteo, Francesco Tentoni, Alessia Cavicchioli, Alessandro Di Martino, Mirco Lo Presti, Francesco Iacono, Elizaveta Kon, Maurilio Marcacci
BACKGROUND: The management of the postoperative period after knee arthroscopic surgery may be challenging because surgical trauma deeply alters the joint microenvironment, causing the release of several catabolic molecules and proinflammatory factors that might slow down functional recovery. The possibility of using hyaluronic acid (HA) to promote postoperative pain relief and expedite functional improvement seems attractive, considering its biological properties. PURPOSE: The aim of the present double-blind randomized controlled trial was to evaluate the effects, in terms of pain control and functional recovery, provided by a single HA injection performed at the end of arthroscopic meniscectomy...
December 2016: American Journal of Sports Medicine
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