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https://www.readbyqxmd.com/read/29133641/simultaneous-use-of-amniotic-membrane-and-mitomycin-c-in-trabeculectomy-for-primary-glaucoma
#1
Usha Yadava, Kirti Jaisingh, Sonal Dangda, Prolima Thacker, Kirti Singh, Yashpal Goel
PURPOSE: This study aimed to propose the role of amniotic membrane transplantation (AMT) as an additional modulator in primary Mitomycin C (MMC)-augmented trabeculectomy. METHODS: This was a randomized prospective interventional study. Forty eyes of 39 adult patients with uncontrolled primary glaucoma were randomly divided into two equal groups. Control group underwent trabeculectomy augmented with MMC while the study group underwent additional AMT. Patients were followed up for 12 months and outcomes measured were intraocular pressure (IOP), need for additional intervention, and bleb morphology...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29132016/children-s-representation-of-abstract-relations-in-relational-array-match-to-sample-tasks
#2
Jean-Rémy Hochmann, Arin S Tuerk, Sophia Sanborn, Rebecca Zhu, Robert Long, Meg Dempster, Susan Carey
Five experiments compared preschool children's performance to that of adults and of non-human animals on match to sample tasks involving 2-item or 16-item arrays that varied according to their composition of same or different items (Array Match-to-Sample, AMTS). They establish that, like non-human animals in most studies, 3- and 4-year-olds fail 2-item AMTS (the classic relational match to sample task introduced into the literature by Premack, 1983), and that robust success is not observed until age 6. They also establish that 3-year-olds, like non-human animal species, succeed only when they are able to encode stimuli in terms of entropy, a property of an array (namely its internal variability), rather than relations among the individuals in the array (same vs...
November 10, 2017: Cognitive Psychology
https://www.readbyqxmd.com/read/29098940/nitrogen-and-phosphorus-removal-processes-under-different-aeration-strength-in-principal-type-tank-of-alternate-multiple-tanks-system-and-process-control
#3
Zheqin Dai, Xiwu Lu, Zhaoqian Jing
The Alternate multiple tanks (AMT) system was originated by Southeast University to meet pressing requirements of new highly-compact sewage treatment with cost-effective balance and automated management. DO and ORP as economic monitoring indicators are closely linked to nutrients variations and controlling strategy. Thus this paper was to investigate the N and P periodic variations and removal mechanisms under different aeration strengths in scope of principal-type tank in AMT, and the relationship between nutrients and DO, ORP...
November 3, 2017: Environmental Technology
https://www.readbyqxmd.com/read/29068239/a-phytophthora-palmivora-extracellular-cystatin-like-protease-inhibitor-targets-papain-to-contribute-to-virulence-on-papaya
#4
Rebecca Gumtow, Dongliang Wu, Janice Uchida, Miaoying Tian
Papaya fruits, stems and leaves are rich in papain, a cysteine protease that has been shown to mediate plant defense against pathogens and insects. Yet the oomycete Phytophthora palmivora is a destructive pathogen that infects all parts of papaya plants, suggesting that it has evolved cysteine protease inhibitors to inhibit papain to enable successful infection. Out of five putative cystatin-like extracellular protease inhibitors (PpalEPICs) from P. palmivora transcriptomic sequence data, PpalEPIC8 appeared to be unique to P...
October 25, 2017: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/29036302/a-prospective-observational-study-to-investigate-utility-of-the-delirium-observational-screening-scale-doss-to-detect-delirium-in-care-home-residents
#5
E A Teale, T Munyombwe, M Schuurmans, N Siddiqi, J Young
Background: care home residents are particularly at risk of delirium due to high prevalence of dementia. The Delirium Observation Screening Scale (DOSS) identifies behavioural changes associated delirium onset that nursing staff are uniquely placed to recognise. We tested the psychometric properties of the DOSS in UK care homes compared with the Confusion Assessment Method (CAM). Design: prospective observational cohort study performed between 1 March 2015 and 30 June 2016...
October 5, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29034003/cellulase-hyper-production-by-trichoderma-reesei-mutant-seu-7-on-lactose
#6
Chengcheng Li, Fengming Lin, Le Zhou, Lei Qin, Bingzhi Li, Zhihua Zhou, Mingjie Jin, Zhan Chen
BACKGROUND: The induction of cellulase production by insoluble carbon source cellulose was a common and efficient strategy, but has some drawbacks, such as difficult fermentation operation, substantial cellulase loss, long fermentation time, and high energy-consumption, resulting in high cost of cellulase production in industry. These drawbacks can be overcome if soluble carbon sources are utilized as the inducers for cellulase production. However, until now the induction efficiency of most soluble carbon sources, especially lactose and glucose, is still inferior to cellulose despite extensive efforts have been made by either optimizing the fermentation process or constructing the recombinant strains...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29032875/ventilator-use-by-emergency-medical-services-during-911-calls-in-the-united-states
#7
Mazen El Sayed, Hani Tamim, Aurelie Mailhac, Mann N Clay
BACKGROUND: Emergency and transport ventilators use in the prehospital field is not well described. This study examines trends of ventilator use by EMS agencies during 911 calls in the United States and identifies factors associated with this use. METHODS: This retrospective study used four consecutive releases of the US National Emergency Medical Services Information System (NEMSIS) public research dataset (2011-2014) to describe scene EMS activations (911 calls) with and without reported ventilator use...
October 6, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29032248/a-critical-role-of-amt2-1-in-root-to-shoot-translocation-of-ammonium-in-arabidopsis
#8
Ricardo F H Giehl, Alberto M Laginha, Fengying Duan, Doris Rentsch, Lixing Yuan, Nicolaus von Wirén
Ammonium uptake in plant roots is mediated by AMT/MEP/Rh-type ammonium transporters. Out of five AMTs being expressed in Arabidopsis roots, four AMT1-type transporters contribute to ammonium uptake, whereas no physiological function has so far been assigned to the only homolog belonging to the MEP subfamily, AMT2;1. Based on the observation that under ammonium supply, the transcript levels of AMT2;1 increased and its promoter activity shifted preferentially to the pericycle, we assessed the contribution of AMT2;1 to xylem loading...
November 6, 2017: Molecular Plant
https://www.readbyqxmd.com/read/29028555/shifting-characteristics-of-ecstasy-users-ages-12-34-in-the-united-states-2007-2014
#9
Joseph J Palamar, Pia M Mauro, Benjamin H Han, Silvia S Martins
BACKGROUND: Ecstasy/MDMA has been one of the most prevalent party drugs for decades, and powder ecstasy recently increased in popularity. We examined trends in use to determine who to best target for prevention and harm reduction. METHODS: Secondary analysis of the 2007-2014 National Survey on Drug Use and Health, a repeated cross-sectional, nationally representative probability sample, was conducted. Linear trends in past-year ecstasy use and trends in demographic and other past-year substance use characteristics among ecstasy users were examined among participants ages 12-34 (N=332,560)...
December 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28993893/identification-of-arbuscular-mycorrhiza-inducible-nitrate-transporter-1-peptide-transporter-family-npf-genes-in-rice
#10
Navina Drechsler, Pierre-Emmanuel Courty, Daphnée Brulé, Reinhard Kunze
Arbuscular mycorrhizal fungi (AMF) colonize up to 90% of all land plants and facilitate the acquisition of mineral nutrients by their hosts. Inorganic orthophosphate (Pi) and nitrogen (N) are the major nutrients transferred from the fungi to plants. While plant Pi transporters involved in nutrient transfer at the plant-fungal interface have been well studied, the plant N transporters participating in this process are largely unknown except for some ammonium transporters (AMT) specifically assigned to arbuscule-colonized cortical cells...
October 9, 2017: Mycorrhiza
https://www.readbyqxmd.com/read/28993242/a-distinct-microrna-expression-profile-is-associated-with-%C3%AE-11-c-methyl-l-tryptophan-amt-pet-uptake-in-epileptogenic-cortical-tubers-resected-from-patients-with-tuberous-sclerosis-complex
#11
Shruti Bagla, Daniela Cukovic, Eishi Asano, Sandeep Sood, Aimee Luat, Harry T Chugani, Diane C Chugani, Alan A Dombkowski
Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in various organs and arises due to mutations in the TSC1 or TSC2 genes. TSC mutations lead to a range of neurological manifestations including epilepsy, cognitive impairment, autism spectrum disorders (ASD), and brain lesions that include cortical tubers. There is evidence that seizures arise at or near cortical tubers, but it is unknown why some tubers are epileptogenic while others are not. We have previously reported increased tryptophan metabolism measured with α[(11)C]-methyl-l-tryptophan (AMT) positron emission tomography (PET) in epileptogenic tubers in approximately two-thirds of patients with tuberous sclerosis and intractable epilepsy...
October 7, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28993134/sepsis-caused-by-bloodstream-infection-in-patients-in-the-intensive-care-unit-the-impact-of-inactive-empiric-antimicrobial-therapy-on-outcome
#12
Daniel Brooks, Padmaja Polubothu, D Young, M G Booth, A Smith
BACKGROUND: Sepsis is one of the leading causes of death in the UK. AIMS: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU mortality, 90-day mortality and length of hospital stay. Additionally, we wanted to identify risk factors for receiving inactive AMT. METHODS: This was a retrospective observational study conducted at Glasgow Royal Infirmary ICU between January 2010 and December 2013, with 12,000 blood cultures taken over this time period, of which n=127 were deemed clinically significant...
October 6, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28982146/active-and-resting-motor-threshold-are-efficiently-obtained-with-adaptive-threshold-hunting
#13
Christelle B Ah Sen, Hunter J Fassett, Jenin El-Sayes, Claudia V Turco, Mahdiya M Hameer, Aimee J Nelson
Transcranial magnetic studies typically rely on measures of active and resting motor threshold (i.e. AMT, RMT). Previous work has demonstrated that adaptive threshold hunting approaches are efficient for estimating RMT. To date, no study has compared motor threshold estimation approaches for measures of AMT, yet this measure is fundamental in transcranial magnetic stimulation (TMS) studies that probe intracortical circuits. The present study compared two methods for acquiring AMT and RMT: the Rossini-Rothwell (R-R) relative-frequency estimation method and an adaptive threshold-hunting method based on maximum-likelihood parameter estimation by sequential testing (ML-PEST)...
2017: PloS One
https://www.readbyqxmd.com/read/28979288/wheat-ammonium-transporter-amt-gene-family-diversity-and-possible-role-in-host-pathogen-interaction-with-stem-rust
#14
Tianya Li, Kai Liao, Xiaofeng Xu, Yue Gao, Ziyuan Wang, Xiaofeng Zhu, Baolei Jia, Yuanhu Xuan
Ammonium transporter (AMT) proteins have been reported in many plants, but no comprehensive analysis was performed in wheat. In this study, we identified 23 AMT members (hereafter TaAMTs) using a protein homology search in wheat genome. Tissue-specific expression analysis showed that TaAMT1;1a, TaAMT1;1b, and TaAMT1;3a were relatively more highly expressed in comparison with other TaAMTs. TaAMT1;1a, TaAMT1;1b, and TaAMT1;3a-GFP were localized in the plasma membrane in tobacco leaves, and TaAMT1;1a, TaAMT1;1b, and TaAMT1;3a successfully complemented a yeast 31019b strain in which ammonium uptake was deficient...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28976415/amniotic-membrane-grafts-to-reduce-pterygium-recurrence
#15
Ronald Rosen
PURPOSE: To demonstrate the long-term outcome of pterygium surgery with adjunctive amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC) in a large case series. METHODS: Medical records were retrieved for this noncomparative retrospective study of all patients who had pterygium excision with adjunctive AMT and intraoperative MMC, from October 2010 to June 2016 with at least 6 months of follow-up. RESULTS: There were a total of 556 eyes of 535 patients (291 males and 244 females) with average age of 51...
October 2, 2017: Cornea
https://www.readbyqxmd.com/read/28969790/molecular-identification-of-tobacco-ntamt1-3-that-mediated-ammonium-root-influx-with-high-affinity-and-improved-plant-growth-on-ammonium-when-overexpressed-in-arabidopsis-and-tobacco
#16
Teng-Fei Fan, Xiao-Yuan Cheng, Dong-Xue Shi, Ming-Jie He, Chao Yang, Lu Liu, Chang-Jun Li, Yi-Chen Sun, Yi-Yin Chen, Chen Xu, Lei Zhang, Lai-Hua Liu
Although biological functions of ammonium (NH4(+)) transporters (AMTs) have been intensively studied in many plant species, little is known about molecular bases responsible for NH4(+) movement in tobacco. Here, we reported the identification and functional characterization of a putative NH4(+) transporter NtAMT1.3 from tobacco (Nicotiana tabacum). Analysis in silico showed that NtAMT1.3 encoded an integral membrane protein containing 464 amino acid residues and exhibiting 10 predicted transmembrane α-helices...
November 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28965220/molecular-tools-for-gene-manipulation-in-filamentous-fungi
#17
REVIEW
Shunxian Wang, Haiqin Chen, Xin Tang, Hao Zhang, Wei Chen, Yong Q Chen
Functional genomics of filamentous fungi has gradually uncovered gene information for constructing 'cell factories' and controlling pathogens. Available gene manipulation methods of filamentous fungi include random integration methods, gene targeting technology, gene editing with artificial nucleases and RNA technology. This review describes random gene integration constructed by restriction enzyme-mediated integration (REMI); Agrobacterium-mediated transformation (AMT); transposon-arrayed gene knockout (TAGKO); gene targeting technology, mainly about homologous recombination; and modern gene editing strategies containing transcription activator-like effector nucleases (TALENs) and a clustered regularly interspaced short palindromic repeat/associated protein system (CRISPR/Cas) developed in filamentous fungi and RNA technology including RNA interference (RNAi) and ribozymes...
September 30, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28954025/surgical-amniotic-membrane-transplantation-after-conjunctival-and-limbal-tumor-excision
#18
Seniz Engur Goktas, Yasemin Katircioglu, Tuba Celik, Firdevs Ornek
Purpose: To evaluate the clinical results of patients treated by amniotic membrane transplantation (AMT) following excision of conjunctival and limbal tumors. Methods: A total of 14 eyes of 14 patients who underwent AMT after total lesion-free tumor excision and perilesional cryotherapy were evaluated. Results: The excised tumors comprised 7 conjunctival intraepithelial neoplasia, 5 conjunctival nevus, 1 primary acquired melanosis, and 1 squamous cell carcinoma...
July 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28947204/preparation-of-a-reversed-phase-anion-exchange-mixed-mode-spherical-sorbent-by-pickering-emulsion-polymerization-for-highly-selective-solid-phase-extraction-of-acidic-pharmaceuticals-from-wastewater
#19
Chaonan Huang, Yun Li, Jiajia Yang, Junyu Peng, Jing Jin, Dhanjai, Jincheng Wang, Jiping Chen
The present work represents a simple and effective preparation of a novel mixed-mode anion-exchange (MAX) sorbent based on porous poly[2-(diethylamino)ethyl methacrylate-divinylbenzene] (poly(DEAEMA-DVB)) spherical particles synthesized by one-step Pickering emulsion polymerization. The poly(DEAEMA-DVB) particles were quaternized with 1,4-butanediol diglycidyl ether (BDDE) followed by triethylamine (TEA) via epoxy-amine reaction to offer strong anion exchange properties. The synthesized MAX sorbent was characterized by scanning electron microscopy, Fourier-transform infrared spectroscopy, nitrogen adsorption-desorption measurements and elemental analysis...
September 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28935187/differentiation-of-motor-evoked-potentials-elicited-from-multiple-forearm-muscles-an-investigation-with-high-density-surface-electromyography
#20
J L Neva, A Gallina, S Peters, S J Garland, L A Boyd
Transcranial magnetic stimulation (TMS) is a non-invasive method to measure corticospinal excitability of the primary motor cortex. However, motor evoked potentials (MEPs) elicited by TMS in a target muscle are variable; inconsistent MEPs may be due to overlapping cortical muscle representations and/or volume conduction from neighbouring muscles. The source of variable muscle responses may not be apparent using conventional bipolar electromyography (EMG), particularly over areas with several distinct neighbouring muscles (e...
December 1, 2017: Brain Research
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