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https://www.readbyqxmd.com/read/28346847/does-acute-normobaric-hypoxia-induce-anapyrexia-in-adult-humans
#1
Yongsuk Seo, Hayden D Gerhart, Jeremiah Vaughan, Jung-Hyun Kim, Ellen L Glickman
Seo, Yongsuk, Hayden D. Gerhart, Jeremiah Vaughan, Jung-Hyun Kim, and Ellen L. Glickman. Does acute normobaric hypoxia induce anapyrexia in adult humans? High Alt Med Biol 00:000-000, 2017.-Exposure to hypoxia is known to induce a reduction in core body temperature as a protective mechanism, which has been shown in both animals and humans. The purpose of this study was to test if acute exposure to normobaric hypoxia (NH) induces anapyrexia in adult humans in association with decreased peripheral oxygen saturation (SpO2)...
March 27, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28346223/early-rectal-cancer-a-choice-between-local-excision-and-transabdominal-resection-a-review-of-the-literature-and-current-guidelines
#2
Giuseppe Pappalardo, Massimo Chiaretti
INTRODUCTION: Indication for Local Excision (LE) or Trans Abdominal Resections with Total Mesorectal Excision (TAR) in Early Rectal Cancer (ERC) are still controversial. MATERIAL OF STUDY: We reviewed meta-analyses, scientific societies guidelines, randomized and controlled clinical trials from 1999 to 2016 for a total of 146,231 patients. We included in our analysis the accuracy of different tools of investigation, the reliability of the endoscopic biopsies and compared the results of the various LE and TAR...
March 27, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28345614/prognosis-and-value-of-preoperative-radiotherapy-in-locally-advanced-rectal-signet-ring-cell-carcinoma
#3
Chun-Run Ling, Rui Wang, Mo-Jin Wang, Jie Ping, Wen Zhuang
As well known, signet-ring cell carcinoma (SRCC) is a rare histological subtype of colorectal adenocarcinoma, which has been associated with poor prognosis and resistant to non-surgery therapy compared with common adenocarcinoma. In this study, we assessed the effect of preoperative radiotherapy (PRT) for locally advanced rectal SRCC in a large patient group from the Surveillance, Epidemiology, and End Results program (SEER, 1988-2011) database. SRCC was found in 0.9% (n = 622) rectal cancer (RC) patients in our study...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28344794/does-calprotectin-level-identify-a-subgroup-among-patients-suffering-from-irritable-bowel-syndrome-results-of-a-prospective-study
#4
Chloé Melchior, Moutaz Aziz, Typhaine Aubry, Guillaume Gourcerol, Muriel Quillard, Alberto Zalar, Moïse Coëffier, Pierre Dechelotte, Anne-Marie Leroi, Philippe Ducrotté
BACKGROUND: Irritable bowel syndrome is a multifactorial disease. Although faecal calprotectin has been shown to be a reliable marker of intestinal inflammation, its role in irritable bowel syndrome remains debated. OBJECTIVE: The aims of this prospective study were to select a subgroup of irritable bowel syndrome patients and to characterise those patients with high faecal calprotectin by systematic work-up. METHODS: Calprotectin levels were determined by enzyme-linked immunosorbent assay test in consecutive irritable bowel syndrome patients fulfilling Rome III criteria in whom normal colonoscopy and appropriate tests had excluded organic disease...
March 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28344761/acute-rectal-ischaemia-following-emergency-abdominal-aortic-aneurysm-surgery
#5
Frances R Mosley, Sobia Akhtar, Rina George, Woolagasen R Pillay
We present a case of isolated rectal ischaemia, a rare complication after emergency surgery for a ruptured abdominal aneurysm. We discuss the possible aetiology of this condition and how this rare condition may be missed unless care is taken at the time of reoperation.
October 2016: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28344401/profile-and-artificial-insemination-practices-of-technicians-and-the-artificial-insemination-success-rates-in-leyte-samar-and-biliran-philippines-2011-2015
#6
Adrian P Ybañez, Rochelle Haidee D Ybañez, Maxine O Caindec, Louie V Mani, Julius V Abela, Edgar S Nuñez, Johnson T Royo, Ivy Fe M Lopez
BACKGROUND: Artificial insemination (AI) is a reproductive biotechnology that may be influenced by several factors, including the profile of the technicians and the practices used. Assessing technician's profile and their AI practices can be significant in improving AI success rate. AIM: This study aimed to know the profile and current practices used by AI technicians (AITs), to determine the success rates of AI in water buffaloes in Leyte, Samar, and Biliran from 2011 to 2015, and to evaluate the possible association between the parameters investigated...
February 2017: Veterinary World
https://www.readbyqxmd.com/read/28343946/double-stranded-rna-induces-cathelicidin-expression-in-the-intestinal-epithelial-cells-through-phosphatidylinositol-3-kinase-protein-kinase-c%C3%AE-sp1-pathway-and-ameliorates-shigellosis-in-mice
#7
Atri Ta, Bhupesh Kumar Thakur, Pujarini Dutta, Ritam Sinha, Hemanta Koley, Santasabuj Das
Cathelicidin antimicrobial peptide is a key component of the host innate immune system. It is constitutively expressed by the intestinal epithelial cells, but induced at further higher levels by different host-derived and microbial stimuli, including the ligands for Toll-like receptors (TLRs). While the underlying mechanisms of cathelicidin expression remain incompletely understood, altered expression may be associated with gastro-intestinal infections and inflammatory diseases. We demonstrate here that viral double-stranded RNA and its synthetic analog poly(I:C) are potent and tissue-specific inducers of cathelicidin mRNA and protein expression in the mouse as well as human intestinal epithelial cells...
March 24, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28343572/effect-of-the-timing-of-ice-slurry-ingestion-for-precooling-on-endurance-exercise-capacity-in-a-warm-environment
#8
Keisuke Takeshima, Sumire Onitsuka, Zheng Xinyan, Hiroshi Hasegawa
It has been demonstrated that precooling with ice slurry ingestion enhances endurance exercise capacity in the heat. However, no studies have yet evaluated the optimal timing of ice slurry ingestion for precooling. This study aimed to investigate the effects of varying the timing of ice slurry ingestion for precooling on endurance exercise capacity in a warm environment. Ten active male participants completed 3 experimental cycling trials to exhaustion at 55% peak power output (PPO) after 15min of warm-up at 30% PPO at 30°C and 80% relative humidity...
April 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28343563/effect-of-thermal-exposure-on-physiological-adaptability-and-seminal-attributes-of-rams-under-semi-arid-environment
#9
Kalyan De, Davendra Kumar, Krishnappa Balaganur, Vijay Kumar Saxena, Palanisamy Thirumurugan, Syed Mohammed Khursheed Naqvi
Thermal stress in hot semi-arid environment is a major limitation of sheep production in tropical and sub-tropical climatic condition. The animals tend to maintain homeostasis through physiological adjustments in a hot environment (maximum temperature reaches up to 47.5°C). Therefore, the present study was carried out to assess the effect of thermal exposure on physiological adaptability and seminal attributes of rams under semi-arid environment. The experiment was conducted for eight weeks involving sixteen Malpura crossbred rams (GMM: Garole X Malpura X Malpura)...
April 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28342633/pca3-as-a-second-line-biomarker-in-a-prospective-controlled-randomized-opportunistic-prostate-cancer-screening-programme
#10
J Rubio-Briones, J Casanova, F Martínez, J L Domínguez-Escrig, A Fernández-Serra, R Dumont, M Ramírez-Backhaus, A Gómez-Ferrer, A Collado, L Rubio, A Molina, M Vanaclocha, D Sala, J A Lopez-Guerrero
OBJECTIVES: PCA3 performance as a single second line biomarker is compared to the European Randomised Study of Screening for Prostate Cancer risk calculator model 3 (ERSPC RC-3) in an opportunistic screening in prostate cancer (PCa). MATERIAL AND METHODS: 5,199 men, aged 40-75y, underwent prostate-specific antigen (PSA) screening and digital rectal examination (DRE). Men with a normal DRE and PSA ≥3ng/ml had a PCA3 test done. All men with PCA3 ≥35 underwent an initial biopsy (IBx) -12 cores-...
March 22, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28342240/combination-of-growth-pattern-and-tumor-regression-identifies-a-high-risk-group-in-neoadjuvant-treated-rectal-cancer-patients
#11
Jonas Jessberger, Katharina Erlenbach-Wünsch, Rebecca Posselt, Marlen Haderlein, Abbas Agaimy, Rainer Fietkau, Arndt Hartmann, Luitpold Distel
AIM: In this study we analyzed the prognostic effect of E-Cadherin expression, the growth pattern of the tumor and the regression grade in a rectal cancer cohort treated with neoadjuvant radiochemotherapy. METHOD: 223 patients with rectal cancer treated with neoadjuvant radiochemotherapy followed by surgery were included. 88 biopsies prior to radiochemotherapy and 213 tumor resections with an average of 55 days post-RCT were investigated. Protein expression of E-cadherin and tumor growth pattern (solid-glandular vs...
March 25, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28342192/intravenous-versus-non-intravenous-benzodiazepines-for-the-abortion-of-seizures-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#12
Abdussalam Alshehri, Ahmad Abulaban, Rakan Bokhari, Suleiman Kojan, Majid Alsalamah, Mazen Ferwana, Mohammad Hassan Murad
BACKGROUND: The acquisition of intravenous access in the actively convulsing patient is difficult. This often delays the administration of the intravenous benzodiazepine necessary for seizure abortion. Delays in seizure abortion are associated with increased pharmacoresistance, increased risk of neuronal injury, worse patient outcomes and increased morbidity. OBJECTIVE: To assess whether the delay imposed by IV access acquisition is justified by improved outcomes...
March 25, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28342119/returns-to-operating-room-after-colon-and-rectal-surgery-in-a-tertiary-care-academic-medical-center-a-valid-measure-of-surgical-quality
#13
Amy L Lightner, Amy E Glasgow, Elizabeth B Habermann, Robert R Cima
INTRODUCTION: Returns to the operating room (ROR) have been suggested as a marker of surgical quality. Increasingly, quality and value metrics are utilized for reimbursement as well as public reporting to inform health care consumers. We sought to understand the etiology of ROR and assess the validity of simple ROR as a quality metric. METHODS: This was a single referral center retrospective review of all colon and rectal operations between January 1, 2014 and December 31, 2014...
March 24, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28341803/closing-the-brief-case-benign-rectal-polyp-with-schistosoma-mansoni
#14
EDITORIAL
Mohsin Jamal, Omar Rayes, Linoj Samuel, Robert Tibbetts, Jason D Pimentel
No abstract text is available yet for this article.
April 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28341802/the-brief-case-benign-rectal-polyp-with-schistosoma-mansoni
#15
EDITORIAL
Mohsin Jamal, Omar Rayes, Linoj Samuel, Robert Tibbetts, Jason D Pimentel
No abstract text is available yet for this article.
April 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28341231/rectal-suction-biopsy-with-calretinin-immunohistochemistry-in-patients-suspected-with-residual-aganglionosis-after-operation-for-hirschsprung-disease
#16
Viet Quoc Tran, Dinh Quang Truong, Philippe Goyens, Henri Steyaert
INTRODUCTION: This study investigates the use of rectal suction biopsy (RSB) with calretinin immunohistochemical staining (CIS) in patients suspected of having abnormally innervated bowel after pull through operation for Hirschsprung disease (HD). METHOD: This study was conducted in Children's Hospital 2, Ho Chi Minh City from January 2015 through June 2016. Patients suspected with abnormally innervated bowel after pull through operation for HD were submitted for a RSB with CIS...
March 14, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28339306/descriptive-characteristics-of-colon-and-rectal-cancer-recurrence-in-a-danish-population-based-study
#17
Ashley C Holmes, Anders H Riis, Rune Erichsen, Veronika Fedirko, Eva Bjerre Ostenfeld, Mogens Vyberg, Ole Thorlacius-Ussing, Timothy L Lash
BACKGROUND: Recurrence is a common outcome among patients that have undergone an intended curative resection for colorectal cancer. However, data on factors that influence colorectal cancer recurrence are sparse. We report descriptive characteristics of both colon and rectal cancer recurrence in an unselected population. MATERIAL AND METHODS: We identified 21,152 patients with colorectal cancer diagnosed between May 2001 and December 2011 and registered with the Danish Colorectal Cancer Group...
March 24, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28339103/iterative-dataset-optimization-in-automated-planning-implementation-for-breast-and-rectal-cancer-radiotherapy
#18
Jiawei Fan, Jiazhou Wang, Zhen Zhang, Weigang Hu
PURPOSE: To develop a new automated treatment planning solution for breast and rectal cancer radiotherapy. METHODS: The automated treatment planning solution developed in this study includes selection of the iterative optimized training dataset, dose volume histogram (DVH) prediction for the organs at risk (OARs), and automatic generation of clinically acceptable treatment plans. The iterative optimized training dataset is selected by an iterative optimization from 40 treatment plans for left-breast and rectal cancer patients who received radiation therapy...
March 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28338306/implantation-of-a-biodegradable-rectum-balloon-implant-tips-tricks-and-pitfalls
#19
Ben G L Vanneste, Kees van De Beek, Ludy Lutgens, Philippe Lambin
INTRODUCTION: A rectum balloon implant (RBI) is a new device to spare rectal structures during prostate cancer radiotherapy. The theoretical advantages of a RBI are to reduce the high radiation dose to the anterior rectum wall, the possibility of a post-implant correction, and their predetermined shape with consequent predictable position. OBJECTIVE: To describe, step-by-step, our mini-invasive technique for hands-free transperineal implantation of a RBI before start of radiotherapy treatment...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28338169/-meta-analysis-of-extralevator-abdominoperineal-excision-for-rectal-cancer
#20
Yilin Chen, Pan Chi
OBJECTIVE: To evaluate the efficacy of extralevator abdominoperineal excision (ELAPE) of rectal cancer. METHODS: PubMed, Cochrane Library and Embase database were searched for clinical studies comparing the ELAPE and abdominoperineal excision (APE) for rectal cancer between 2007 and 2016. Two reviewers independently screened the articles and extracted the data. The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of the observational studies and the score more than 5 points was the inclusion criteria...
March 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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