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https://www.readbyqxmd.com/read/28231568/fiber-connections-of-the-caudal-corpus-cerebelli-with-special-reference-to-the-intrinsic-circuitry-in-a-teleost-oreochromis-niloticus
#1
Kosuke Imura, Naoyuki Yamamoto, Masami Yoshimoto, Masato Endo, Kengo Funakoshi, Hironobu Ito
The caudal part of the corpus cerebelli of Nile tilapia can be divided into dorsal and ventral regions. The granule cell layer of the dorsal (dGL) and ventral (vGL) regions of the caudal corpus cerebelli is known to receive indirect inputs from the telencephalon relayed by the nucleus paracommissuralis. The descending pathways are topographically organized, and the dGL and vGL receive inputs from different dorsal telencephalic parts. The caudal corpus cerebelli, in turn, projects extracerebellar efferents. However, it remains unknown how the descending telencephalic inputs are processed within the cerebellum...
February 24, 2017: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/28231323/even-good-bots-fight-the-case-of-wikipedia
#2
Milena Tsvetkova, Ruth García-Gavilanes, Luciano Floridi, Taha Yasseri
In recent years, there has been a huge increase in the number of bots online, varying from Web crawlers for search engines, to chatbots for online customer service, spambots on social media, and content-editing bots in online collaboration communities. The online world has turned into an ecosystem of bots. However, our knowledge of how these automated agents are interacting with each other is rather poor. Bots are predictable automatons that do not have the capacity for emotions, meaning-making, creativity, and sociality and it is hence natural to expect interactions between bots to be relatively predictable and uneventful...
2017: PloS One
https://www.readbyqxmd.com/read/28230626/resiliency-and-quality-of-life-trajectories-after-injury
#3
Ben L Zarzaur, Teresa M Bell, Stephen A Zanskas
BACKGROUND: Injury can greatly impact patients' long-term quality of life. Resilience refers to an individual's ability to positively adapt after facing stress or trauma. The objective of this study was to examine the relationship between pre-injury resiliency scores and quality of life after injury. METHODS: 225 adults admitted with an injury severity score > 10 but without neurological injury were included. The SF-36 was administered at the time of admission and repeated at 1, 2, 4 and 12 months after injury...
February 23, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28230403/development-of-essentialist-thinking-about-religion-categories-in-northern-ireland-and-the-united-states
#4
Kirsty Smyth, Aidan Feeney, R Cole Eidson, John D Coley
Social essentialism, the belief that members of certain social categories share unobservable properties, licenses expectations that those categories are natural and a good basis for inference. A challenge for cognitive developmental theory is to give an account of how children come to develop essentialist beliefs about socially important categories. Previous evidence from Israel suggests that kindergarteners selectively engage in essentialist reasoning about culturally salient (ethnicity) categories, and that this is attenuated among children in integrated schools...
March 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28230275/the-development-and-correlates-of-gender-role-attitudes-in-african-american-youth
#5
Chun Bun Lam, Christine Stanik, Susan M McHale
This research examined the longitudinal trajectories and family correlates of gender role attitudes in African American youth in a sample of 166 sibling pairs residing with their mothers and fathers. Multilevel modelling revealed that (1) girls and boys exhibited significant declines in gender attitude traditionality from ages 9 to 15 that levelled off through age 18, (2) mothers' (but not fathers') gender role attitude traditionality was positively related to youth's attitude traditionality, and (3) within-person variation in mothers' (but not fathers') racial discrimination experiences was negatively related to within-person variation in youth's gender role attitude traditionality...
February 23, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/28230057/ensemble-and-single-molecule-dynamics-of-ift-dynein-in-caenorhabditis-elegans-cilia
#6
Jona Mijalkovic, Bram Prevo, Felix Oswald, Pierre Mangeol, Erwin J G Peterman
Cytoplasmic dyneins drive microtubule-based, minus-end directed transport in eukaryotic cells. Whereas cytoplasmic dynein 1 has been widely studied, IFT dynein has received far less attention. Here, we use fluorescence microscopy of labelled motors in living Caenorhabditis elegans to investigate IFT-dynein motility at the ensemble and single-molecule level. We find that while the kinesin composition of motor ensembles varies along the track, the amount of dynein remains relatively constant. Remarkably, this does not result in directionality changes of cargo along the track, as has been reported for other opposite-polarity, tug-of-war motility systems...
February 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28230056/threshold-of-long-term-survival-of-a-coastal-delphinid-in-anthropogenically-degraded-environment-indo-pacific-humpback-dolphins-in-pearl-river-delta
#7
Leszek Karczmarski, Shiang-Lin Huang, Stephen C Y Chan
Defining demographic and ecological threshold of population persistence can assist in informing conservation management. We undertook such analyses for the Indo-Pacific humpback dolphin (Sousa chinensis) in the Pearl River Delta (PRD) region, southeast China. We use adult survival estimates for assessments of population status and annual rate of change. Our estimates indicate that, given a stationary population structure and minimal risk scenario, ~2000 individuals (minimum viable population in carrying capacity, MVPk) can maintain the population persistence across 40 generations...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229543/developmental-trajectories-of-amphibian-microbiota-response-to-bacterial-therapy-depends-on-initial-community-structure
#8
Leyla R Davis, Laurent Bigler, Douglas C Woodhams
Improving host health through microbial manipulation requires untangling factors that shape the microbiome. There is currently little understanding of how initial community structure may drive the microbiota trajectory across host development or influence bacterial therapy. Probiotic baths of surface symbionts, Pseudomonas fluorescens and Flavobacterium johnsoniae were administered to 240 tadpoles of the midwife toad, Alytes obstetricans in semi-natural outdoor mesocosms originating from geographically and genetically distinct populations in Switzerland...
February 22, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28229478/students-experiences-of-role-relationships-and-learning-in-two-clerkship-models
#9
D Jill Konkin, Carol Suddards
CONTEXT: An increasing number of medical schools around the world are implementing longitudinal integrated clerkships (LICs). The University of Alberta's third-year LIC admits a small group of each class. Those not in the LIC undertake a rotation-based clerkship (RBC). All students have a fourth-year RBC. Meaningful participation in patient care and guidance have been identified as affordances for work-based learning. METHODS: This qualitative study is part of an ongoing research programme conducted in a hermeneutic phenomenological frame...
February 22, 2017: Medical Education
https://www.readbyqxmd.com/read/28229461/how-different-is-a-3d-printed-replica-from-a-conspecific-in-the-eyes-of-a-zebrafish
#10
Tommaso Ruberto, Giovanni Polverino, Maurizio Porfiri
Robotics is emerging as a promising tool for aiding research on animal behavior. The possibility of generating customizable, controllable, and standardized robotic stimuli has been demonstrated through a number of behavioral assays, involving vertebrates and invertebrates. However, the specific appraisal of the nature of robotic stimuli is currently lacking. Here, we attempt to evaluate this aspect in zebrafish, through a within-subject design in which experimental subjects are faced with three experimental conditions...
February 22, 2017: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/28229458/life-course-health-development-of-individuals-with-neurodevelopmental-conditions
#11
REVIEW
Robert J Palisano, Briano Di Rezze, Debra Stewart, Peter L Rosenbaum, Oksana Hlyva, Matthew Freeman, Tram Nguyen, Jan Willem Gorter
The life course health development (LCHD) model by Halfon et al. conceptualizes health development occurring through person-environment transactions that enable well-being and participation in desired social roles throughout life, areas that have not received adequate attention in healthcare. The aim of this 'perspectives' paper is to apply the six core tenets of the LCHD model and the concept of health development trajectories to individuals with lifelong neurodevelopmental conditions. We share the perspective that modifiable aspects of the environment often restrict health development; we then advocate that children, beginning at a young age, should engage in 'real-world' experiences that prepare them for current and future social roles...
February 23, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28229368/internalizing-and-externalizing-problem-behavior-a-test-of-a-latent-variable-interaction-predicting-a-two-part-growth-model-of-adolescent-substance-use
#12
Craig R Colder, Seth Frndak, Liliana J Lengua, Jennifer P Read, Larry W Hawk, William F Wieczorek
Externalizing symptoms robustly predict adolescent substance use (SU); however, findings regarding internalizing symptoms have been mixed, suggesting that there may be important moderators of the relationship between internalizing problems and SU. The present study used a longitudinal community sample (N = 387, 55% female, 83% White) to test whether externalizing symptoms moderated the relationship between internalizing symptoms and trajectories of alcohol and marijuana use from early (age 11-12 years old) to late (age 18-19 years old) adolescence...
February 22, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28229096/a-study-of-global-health-elective-outcomes-a-pediatric-residency-experience
#13
Christiana M Russ, Tony Tran, Melanie Silverman, Judith Palfrey
Background and Objectives: To identify the effects of global health electives over a decade in a pediatric residency program. Methods: This was an anonymous email survey of the Boston Combined Residency alumni funded for global health electives from 2002 to 2011. A test for trend in binomial proportions and logistic regression were used to document associations between elective and participant characteristics and the effects of the electives. Qualitative data were also analyzed. Results: Of the 104 alumni with available email addresses, 69 (66%) responded, describing 94 electives...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28228542/accelerated-simulation-of-evolutionary-trajectories-in-origin-fixation-models
#14
Ashley I Teufel, Claus O Wilke
We present an accelerated algorithm to forward-simulate origin-fixation models. Our algorithm requires, on average, only about two fitness evaluations per fixed mutation, whereas traditional algorithms require, per one fixed mutation, a number of fitness evaluations of the order of the effective population size, Ne Our accelerated algorithm yields the exact same steady state as the original algorithm but produces a different order of fixed mutations. By comparing several relevant evolutionary metrics, such as the distribution of fixed selection coefficients and the probability of reversion, we find that the two algorithms behave equivalently in many respects...
February 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28228027/ab-initio-state-specific-n2-o-dissociation-and-exchange-modeling-for-molecular-simulations
#15
Han Luo, Marat Kulakhmetov, Alina Alexeenko
Quasi-classical trajectory (QCT) calculations are used in this work to calculate state-specific N2(X(1)Σ)+O((3)P)→2N((4)S)+O((3)P) dissociation and N2(X(1)Σ)+O((3)P)→NO(X(2)Π)+N((4)S) exchange cross sections and rates based on the 1(3)A″ and 1(3)A' ab initio potential energy surface by Gamallo et al. [J. Chem. Phys. 119, 2545-2556 (2003)]. The calculations consider translational energies up to 23 eV and temperatures between 1000 K and 20 000 K. Vibrational favoring is observed for dissociation reaction at the whole range of collision energies and for exchange reaction around the dissociation limit...
February 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28228023/reconciling-transition-path-time-and-rate-measurements-in-reactions-with-large-entropic-barriers
#16
Dmitrii E Makarov
Recent experiments and simulation studies showed that protein/DNA folding barriers inferred from folding rates or from potentials of mean force are often much higher than the barriers estimated from the distributions of transition path times. Here a toy model is used to explain a possible origin of this effect: It is shown that when the transition in question involves an entropic barrier, the one-dimensional Langevin model commonly used to interpret experimental data, while adequately predicting the transition rate, fails to describe the properties of the subset of the trajectories that form the transition path ensemble; the latter may still be describable in terms of a one-dimensional model, but with a different potential, just as observed experimentally...
February 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28227942/unified-phase-variables-of-relative-degree-two-for-human-locomotion
#17
Dario J Villarreal, Robert D Gregg, Dario J Villarreal, Robert D Gregg, Robert D Gregg, Dario J Villarreal
A starting point to achieve stable locomotion is synchronizing the leg joint kinematics during the gait cycle. Some biped robots parameterize a nonlinear controller (e.g., input-output feedback linearization) whose main objective is to track specific kinematic trajectories as a function of a single mechanical variable (i.e., a phase variable) in order to allow the robot to walk. A phase variable capable of parameterizing the entire gait cycle, the hip phase angle, has been used to control wearable robots and was recently shown to provide a robust representation of the phase of human gait...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227914/automated-classification-of-pathological-gait-after-stroke-using-ubiquitous-sensing-technology
#18
Elham Dolatabadi, Babak Taati, Alex Mihailidis, Elham Dolatabadi, Babak Taati, Alex Mihailidis, Babak Taati, Alex Mihailidis, Elham Dolatabadi
This study uses machine learning methods to distinguish between healthy and pathological gait. Examples of multi-dimensional pathological and normal gait sequences were collected from post-stroke and healthy individuals in a real clinical setting and with two Kinect sensors. The trajectories of rotational angle and global velocity of selected body joints (hips, spine, shoulders, neck, knees and ankles) over time formed the gait sequences. The combination of k nearest neighbor (kNN) and dynamic time warping (DTW) was used for classification...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227798/upper-limb-kinematics-of-adults-with-cerebral-palsy-on-bilateral-functional-tasks
#19
Carina Lott, Michelle J Johnson, Carina Lott, Michelle J Johnson, Carina Lott, Michelle J Johnson
Adults with cerebral palsy (CP) often show upper limb impairments which impact their ability to execute activities of daily living (ADLs). Three adults with CP and five healthy adults performed three types of bilateral and unilateral ADLs: drink, pour, and pick and place tasks. An affordable bilateral assessment system (BiAS) was used to measure wrist kinematic trajectories. Four metrics, total completion time, maximum velocity, smoothness, and phase difference, were used to evaluate each functional task. Overall, adults with CP took a longer time than the healthy subjects to complete all unilateral functional tasks with their non-dominant hand...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227723/balance-quality-assessment-as-an-early-indicator-of-physical-frailty-in-older-people
#20
Aly Chkeir, Doha Safieddine, D Bera, M Collart, J L Novella, M Drame, David J Hewson, Jacques Duchene, Aly Chkeir, Doha Safieddine, D Bera, M Collart, J L Novella, M Drame, David J Hewson, Jacques Duchene, J L Novella, David J Hewson, Jacques Duchene, M Collart, Aly Chkeir, D Bera, M Drame, Doha Safieddine
Frailty is an increasingly common geriatric condition that results in an increased risk of adverse health outcomes such as falls. The most widely-used means of detecting frailty is the Fried phenotype, which includes several objective measures such as grip strength and gait velocity. One method of screening for falls is to measure balance, which can be done by a range of techniques including the assessment of the Centre of Pressure (CoP) during a balance assessment. The Balance Quality Tester (BQT) is a device based on a commercial bathroom scale that can evaluate balance quality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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