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Penile cancer

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https://www.readbyqxmd.com/read/29153943/survival-outcomes-of-organ-sparing-surgery-partial-penectomy-and-total-penectomy-in-pathological-t1-t2-penile-cancer-report-from-the-national-cancer-data-base
#1
Mohamed H Kamel, Jun Tao, Joseph Su, Mahmoud I Khalil, Nabil K Bissada, Benjamin Schurhamer, Philippe E Spiess, Rodney Davis
PURPOSE: To describe the survival outcomes of organ sparing surgery (OSS), partial penectomy (PP), and total penectomy (TP) in pathological stage pT1/pT2 penile cancer (PC) as reported in the United States National Cancer Data Base. METHODS: Patients with pT1/pT2 PC, treated with surgery as their primary treatment modality were classified into 3 groups according to the type of surgery into OSS, PP, and TP. Patient and tumor characteristics of the groups were compared using bivariate analysis, and Cox- proportional hazard model was used for survival analysis...
November 16, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29152231/does-penile-rehabilitation-have-a-role-in-the-treatment-of-erectile-dysfunction-following-radical-prostatectomy
#2
REVIEW
Gideon Blecher, Khaled Almekaty, Odunayo Kalejaiye, Suks Minhas
In men undergoing radical treatment for prostate cancer, erectile function is one of the most important health-related quality-of-life outcomes influencing patient choice in treatment. Penile rehabilitation has emerged as a therapeutic measure to prevent erectile dysfunction and expedite return of erectile function after radical prostatectomy. Penile rehabilitation involves a program designed to increase the likelihood of return to baseline-level erectile function, as opposed to treatment, which implies the therapeutic treatment of symptoms, a key component of post-radical prostatectomy management...
2017: F1000Research
https://www.readbyqxmd.com/read/29151798/how-to-deal-with-penile-carcinoma-inguinal-metastases-invading-femoral-vessels
#3
Marius Fodor, Bogdan Petrut, Lucian Fodor
Penile cancer accounts for 1-10% of men neoplastic diseases and 30-60% of patients have inguinal metastases at the time of diagnosis. Inguinal metastases of penile cancer with femoral vessel involvement could lead to vascular fistula and hemorrhagic shock. We present 3 consecutive patients with inguinal metastases of penile cancer complicated by infection and hemorrhage from femoral vessels invaded by the tumor. Simultaneous extra-anatomical axillo-femoral bypass graft, wide excision of tumor and groin defect reconstruction was used to achieve "tumor-free" oncologic aim and to save the lower limb...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29149907/mapping-evidence-on-the-distribution-of-human-papillomavirus-related-cancers-in-sub-saharan-africa-scoping-review-protocol
#4
Bridget K M Lekoane, Tivani P Mashamba-Thompson, Themba G Ginindza
BACKGROUND: Despite the introduction of HPV vaccines, the incidence of HPV-related cancers (cervical, penile, anal, vulvar, vagina, head, and neck) in sub-Saharan Africa has been rising. The increasing incidence of these HPV-related cancers has been attributed to changes in lifestyle-related risk factors, most notably sexual behavior. The main objective of this study is to map evidence on the distribution of HIV-related cancers in sub-Saharan Africa (SSA). METHODS AND ANALYSIS: We will conduct a scoping review to explore, describe, and map literature on the distribution of HPV-related cancers in sub-Saharan Africa...
November 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29144629/single-perineal-incision-placement-of-artificial-urinary-sphincter-with-cadaveric-correlation-of-sub-dartos-pump-placement
#5
Cooper R Benson, Hajar I Ayoub, O Lenaine Westney
PURPOSE: We present a novel AUS implantation technique using a single perineal incision for single device placement or in combination with an inflatable penile prosthesis (IPP). Urinary and sexual dysfunction following the management of prostate cancer has a significant impact on the quality of life of our patients. While there are marginal changes in the prosthetic devices, we strive to reduce post-operative morbidity while maximizing efficacy. MATERIALS AND METHODS: We retrospectively reviewed the outcomes of 6 patients who underwent single perineal incision placement of a virgin AUS in 2014, 3 with simultaneous IPP placement...
November 19, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29135152/-masks-of-urogenital-tuberculosis-as-the-cause-of-diagnostic-errors
#6
D P Kholtobin, E V Kulchavenya
Urogenital tuberculosis does not have pathognomonic symptoms, so diagnostic errors are quite common. This systematic review of literature was conducted to identify the causes and estimate the incidence of erroneous diagnoses. We critically evaluated some articles in which the authors describe observations of urogenital tuberculosis as rare and unusual because they never encountered this disease, but in fact that were typical manifestations of genitourinary tuberculosis. The authors analyzed and illustrated the features of urinary tuberculosis in patients with pulmonary tuberculosis, differential diagnosis of urogenital tuberculosis and kidney cancer and male genitourinary organs, described errors in the diagnosis of urethral, testicular, penile, prostatic and epididymal tuberculosis...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29132984/penile-sparing-surgery-for-penile-cancer-a-multicenter-international-retrospective-cohort
#7
Adam Baumgarten, Juan Chipollini, Sylvia Yan, Sarah R Ottenhof, Dominic H Tang, Désirée Draeger, Chris Protzel, Yao Zhu, Ding-Wei Ye, Oliver W Hakenberg, Simon Horenblas, Nicholas A Watkin, Philippe E Spiess
PURPOSE: To evaluate recurrence outcomes of penile sparing surgery (PSS) in the largest multicenter cohort of patients to date. METHODS: We retrospectively identified patients treated with PSS from May 1990 to July 2016 at five tertiary referral institutions. Treatments consisted of circumcision, wide local excision, laser therapy with or without local excision, partial or total glansectomy, and glans resurfacing. Primary endpoint was local recurrence free survival (LRFS) and defined from initial treatment to time of local recurrence and estimated with the Kaplan-Meier method...
November 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29131778/adventures-and-misadventures-in-plastic-surgery-and-soft-tissue-implants
#8
Dana J Lin, Tony T Wong, Gina A Ciavarra, Jonathan K Kazam
Soft-tissue augmentation and implants are increasingly seen by the radiologist as more techniques emerge for a variety of indications and locations. Some surgical and implant procedures are performed for purely cosmetic reasons in otherwise healthy patients seeking to improve their body image, and some are performed for reconstruction after cancer or other chronic illnesses. Abdominoplasty, liposuction, and autologous fat grafting can be performed for abdominal and gluteal contouring. Injection of liquid injectable silicone has historically been fraught with legal issues, although it continues to be used for augmentation in a variety of anatomic locations...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29126815/analysis-of-suicide-risk-in-patients-with-penile-cancer-and-review-of-the-literature
#9
REVIEW
William G Simpson, Zachary Klaassen, Rita P Jen, William M Hughes, Durwood E Neal, Martha K Terris
The treatment for penile cancer has been shown to cause harmful psychiatric symptoms as well as have detrimental effects on well-being. In the past several years, alternatives to total or partial penectomy have emerged, such as chemotherapy, radiation, penile sparing, and laser ablation therapies. A more specific breakdown for penile cancer is in order as the therapy has the potential for life changing surgery. We examined the Surveillance, Epidemiology, and End Results (SEER) database (1973-2013), comprising 28% of the United States population...
October 3, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29111200/quality-of-life-psychological-functioning-and-treatment-satisfaction-of-men-who-have-undergone-penile-prosthesis-surgery-following-robot-assisted-radical-prostatectomy
#10
Brindha Pillay, Daniel Moon, Christopher Love, Denny Meyer, Emma Ferguson, Helen Crowe, Nicholas Howard, Sarah Mann, Addie Wootten
BACKGROUND: Penile prosthesis surgery is last-line treatment to regaining erectile function after radical prostatectomy (RP) for localized prostate cancer. AIMS: To assess quality of life, psychological functioning, and treatment satisfaction of men who underwent penile implantation after RP; the psychosocial correlates of treatment satisfaction and sexual function after surgery; and the relation between patients' and partners' ratings of treatment satisfaction...
October 27, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29108682/postchemotherapy-lymph-node-dissection-for-isolated-retroperitoneal-nodal-recurrences-for-penile-cancer-is-cure-possible-in-highly-selected-cases
#11
Dominic H Tang, Juan Chipollini, Philippe E Spiess
Outcomes for advanced penile carcinoma remain poor with limited options for curative treatment. Nodal recurrences represent worse prognosis and are typically treated with a combination of radiation, chemotherapy, or consolidative resection. Although the ideal management for recurrences remains unknown, there is some evidence supporting the role of chemotherapy followed by consolidative resection. Using a multimodal strategy, we describe the curative potential of postchemotherapy retroperitoneal lymph node dissection for penile cancer patients with isolated locoregional recurrences in the retroperitoneum...
August 18, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29105738/five-year-relative-survival-for-human-papillomavirus-associated-cancer-sites
#12
Hilda Razzaghi, Mona Saraiya, Trevor D Thompson, S Jane Henley, Laura Viens, Reda Wilson
BACKGROUND: Human papillomavirus (HPV) vaccines can potentially prevent greater than 90% of cervical and anal cancers as well as a substantial proportion of vulvar, vaginal, penile, and oropharyngeal cancers caused by certain HPV types. Because more than 38,000 HPV-associated cancers are diagnosed annually in the United States, current studies are needed to understand how relative survival varies for each of these cancers by certain demographic characteristics, such as race and age. METHODS: The authors examined high-quality data from 27 population-based cancer registries covering approximately 59% of the US population...
November 6, 2017: Cancer
https://www.readbyqxmd.com/read/29105175/the-world-health-organization-2016-classification-of-penile-carcinomas-a-review-and-update-from-the-international-society-of-urological-pathology-expert-driven-recommendations
#13
Antonio L Cubilla, Elsa F Velazquez, Mahul B Amin, Jonathan Epstein, Daniel M Berney, Cathy M Corbishley
The International Society of Urological Pathology (ISUP) held an expert driven penile cancer conference in Boston in March 2015 which focused on the new WHO classification of penile cancer: HPV-related tumors and histological grading. The conference was preceded by an online survey of the International Society of Urological Pathology members and the results were used to initiate discussions. Because of the rarity of penile tumors, this was not a consensus but an expert driven conference aiming to assist pathologists who do not see these tumor on a regular basis...
November 3, 2017: Histopathology
https://www.readbyqxmd.com/read/29103967/insight-into-novel-biomarkers-in-penile-cancer-redefining-the-present-and-future-treatment-paradigm
#14
REVIEW
Kamran Zargar-Shoshtari, Pranav Sharma, Philippe E Spiess
INTRODUCTION: Biomarkers are increasingly used in the diagnosis and management of various malignancies. Selected biomarkers may also play a role in management of certain cases of penile carcinoma. In this article, we provide an overview of the clinical role of such markers in the management of penile cancer. METHOD: This is a nonsystematic review of relevant literature assessing biomarkers in penile carcinoma. RESULTS: Evidence of infections with human papillomavirus and its surrogate markers may have important prognostic value in patients with localized or metastatic penile cancer...
November 2, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29097087/laser-ablation-as-monotherapy-for-penile-squamous-cell-carcinoma-a-multi-center-cohort-analysis
#15
Dominic H Tang, Sylvia Yan, Sarah R Ottenhof, Désirée Draeger, Adam S Baumgarten, Juan Chipollini, Chris Protzel, Yao Zhu, Ding-Wei Ye, Oliver W Hakenberg, Simon Horenblas, Nicholas A Watkin, Philippe E Spiess
INTRODUCTION: Although the trend towards penile sparing therapy is increasing for penile squamous cell carcinoma, outcomes for laser ablation therapy have not been widely reported. We assessed the clinical outcomes of penile cancer patients treated with only laser ablation. MATERIALS AND METHODS: A retrospective review was performed on 161 patients across 5 multi-center tertiary referral centers from 1985 to 2015. All patients underwent penile sparing surgery with only laser ablation for squamous cell carcinoma of the penis...
October 30, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29089608/penile-cancer-targeted-therapy-in-penile-cancer-a-new-treatment-paradigm
#16
Mounsif Azizi, Philippe E Spiess
No abstract text is available yet for this article.
October 31, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29089276/long-term-evaluation-of-urinary-sexual-and-quality-of-life-outcomes-after-brachytherapy-for-penile-carcinoma
#17
Dimitri Gambachidze, Cédric Lebacle, Pierre Maroun, Alexandre Escande, Alberto Bossi, Pierre Blanchard, Eric Deutsch, Christine Haie-Meder, Cyrus Chargari
PURPOSE: Brachytherapy (BT) is an effective organ-preserving treatment for selected localized penile carcinoma, providing high local control rates. Long-term functional results however, are still insufficiently evaluated. METHODS AND MATERIALS: All consecutive patients treated with low-dose-rate or pulse-dose-rate BT in our institute for a localized penile cancer and who were in first complete remission and followed for at least 3 years were included. A self-reporting questionnaire was sent, to assess: 1/urinary function, 2/sexual function, 3/cosmetic aspect of the penis, and 4/quality of life...
October 28, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29079166/benefits-of-urologic-dermatologic-consultations-for-the-diagnosis-of-cutaneous-penile-lesions-a%C3%A2-prospective-study
#18
Edouard Fortier, Arnaud Cerruti, Christian Le Clec'h, Abdel-Rahmène Azzouzi, Pierre Bigot
INTRODUCTION: We evaluated the benefits of a specialized consultation created in 2014 for cutaneous penile lesions. MATERIALS AND METHODS: We performed a descriptive prospective study evaluating all patients sent for a monthly urologic-dermatologic consultation at a French university hospital from September 2014 to September 2015 for cutaneous penile lesions. All patients evaluated were included. We collected the demographic data, clinical examination findings, and the proposed diagnosis and treatment for every patient...
October 5, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29071141/management-of-penile-cancer-in-a-singapore-tertiary-hospital
#19
Teck Wei Tan, Sing Joo Chia, Kian Tai Chong
OBJECTIVES: To present our experience of managing penile squamous cell carcinoma (SCC) in a tertiary hospital in Singapore and to evaluate the prognostic value of the inflammatory markers neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR). PATIENTS AND METHODS: We reviewed our prospectively maintained Institutional Review Board-approved urological cancer database to identify men treated for penile SCC at our centre between January 2007 and December 2015...
June 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29064655/saphenous-sparing-laparoscopic-inguinal-lymphadenectomy
#20
Gaetano Chiapparrone, Sebastiano Rapisarda, Bernardino de Concilio, Guglielmo Zeccolini, Michele Antoniutti, Antonio Celia
INTRODUCTION: Inguinal lymphadenectomy is an integral part in the management of penile cancer. Video endoscopic in-guinal lymphadenectomy (VEIL) is emerging as a minimally invasive treatment to reduce postoperative complications. MATERIALS AND METHODS: 62 years old man underwent glansectomy for a squamous cell carcinoma (pT1b). At the physical examination one left inguinal lymph node was detectable (cN1). The chest-abdomen-pelvis CT was negative for me-tastasis...
October 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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