keyword
MENU ▼
Read by QxMD icon Read
search

Penile cancer

keyword
https://www.readbyqxmd.com/read/29327306/strengthening-the-case-for-gender-neutral-and-the-nonavalent-hpv-vaccine
#1
REVIEW
Justin M Hintze, James P O'Neill
PURPOSE: The purpose of this review is to highlight the benefits of gender-neutral and the nonavalent human papillomavirus vaccination. Human papillomavirus infection is the most commonly sexually transmitted disease and is known to cause several types of cancers, including cervical, vulvar, vaginal, penile, oropharyngeal, anal, and rectal. 5% of cancers every year are attributable to human papillomavirus infection, with cervical cancer the most common and oropharyngeal cancer estimated to surpass the incidence of cervical cancer by 2020...
January 11, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29325693/updates-in-the-eighth-edition-of-the-tumor-node-metastasis-staging-classification-for-urologic-cancers
#2
REVIEW
Gladell P Paner, Walter M Stadler, Donna E Hansel, Rodolfo Montironi, Daniel W Lin, Mahul B Amin
The Tumor-Node-Metastasis (TNM) classification on cancer staging, jointly developed by the American Joint Commission on Cancer (AJCC) and the Union for International Cancer Control (UICC), has been updated to its 8th edition with two contemporaneous versions published by the AJCC and UICC. While the goal of the AJCC and UICC is to have identical TNM staging systems, differences exist between these two publications including in the staging of urologic cancers. Among several new facets in the AJCC staging manual, a select few of greater import include an expanded section on imaging, presentation of levels of evidence for significant changes, and endorsement of risk assessment models that pass the AJCC quality criteria such as in prostate cancer...
January 8, 2018: European Urology
https://www.readbyqxmd.com/read/29319487/validation-of-predictors-for-lymph-node-status-in-penile-cancer-results-from-a-population-based-cohort
#3
X Melody Qu, D Robert Siemens, Alexander V Louie, Darwin Yip, Aamer Mahmud
INTRODUCTION: The ability to predict lymph node (LN) status is essential in the management of men with localized squamous cell carcinoma (SCC) of the penis. There has been limited external validation of available risk stratification tools, particularly in routine clinical care. The objective of this study was to evaluate the predictive variables of LN metastases within a large population-based cohort of patients. METHODS: In this population-based cohort study, surgical pathology reports were linked to the population-based Ontario Cancer Registry to identify all patients who were diagnosed with penile cancer in Ontario, Canada...
December 22, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29316825/on-surmounting-the-barriers-to-hpv-vaccination-we-can-do-better
#4
Aria C Attia, Judith Wolf, Ana Nuñez
The major impediment to increased HPV vaccination coverage in young males and females is lack of health care provider recommendation. Despite its efficacy in preventing cervical cancer, HPV vaccination in females (49.5%) and males (37.5%) ages 13 through 17 falls well below the Centers for Disease Control and Prevention's (CDC) Healthy People 2020 target of 80% coverage. Parents' willingness to vaccinate their child has been shown to be much higher when physicians share personal vaccination decisions for their own children as well as what other parents have done at that particular clinic...
January 10, 2018: Annals of Medicine
https://www.readbyqxmd.com/read/29307683/effect-of-starting-penile-rehabilitation-with-sildenafil-immediately-after-robot-assisted-laparoscopic-radical-prostatectomy-on-erectile-function-recovery-a-prospective-randomized-trial
#5
Jung Ki Jo, Seong Jin Jeong, Jong Jin Oh, Sang Wook Lee, Sangchul Lee, Sung Kyu Hong, Seok-Soo Byun, Sang Eun Lee
PURPOSE: It has not been clearly proven in real practice whether early rehabilitation with phosphodiesterase type 5 inhibitors starting immediately after radical prostatectomy improves erectile function recovery more effectively compared with delayed treatment with the same regimen. We performed a prospective randomised trial to identify this. PATIENTS AND METHODS: Patients with prostate cancer and pre-operative International Index of Erectile Function (IIEF)-5 score ≥17 were randomly assigned to regularly receive sildenafil 100mg twice a week for 3 months immediately after urethral catheter removal (early group) or only at 3 months after nerve-sparing robot-assisted laparoscopic radical prostatectomy (delayed group)...
January 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29306557/penile-cancer-sparing-surgery-the-balance-between-oncological-cure-and-functional-preservation
#6
Kevin R Loughlin
Penile cancer presents the dual challenge of achieving oncological cure while ,simultaneously, attempting to preserve sexual function. Herein is a review of the issues involved in appropriate patient selection as well as surgical technique. Recommendations regarding follow up and monitoring are also provided.
January 3, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29299663/prognostic-factors-in-patients-with-penile-cancer-after-surgical-management
#7
Shuguang Wen, Wenbiao Ren, Bichen Xue, Yi Fan, Yongjun Jiang, Chunming Zeng, Yujia Li, Xiongbing Zu
PURPOSE: To examine the possible prognostic factors in patients with penile cancer after surgical management and to identify the independent predictive factors of the prognosis. MATERIALS AND METHODS: Clinical data of 135 patients with penile cancer who underwent surgical management in two medical centers were collected. Follow-up data were available for 103 patients. Possible prognostic factors including patient's age; smoking or not; course of disease; phimosis or not; type of surgery; tumor stage; nodal stage; tumor grade and pathological lymph nodes metastasis were retrospectively analyzed by univariate and multivariate analyses with Cox regression...
January 3, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29289534/penile-length-measurement-technique-and-applications
#8
Ethan P Davoudzadeh, Natan P Davoudzadeh, Ezra Margolin, Peter J Stahl, Doron S Stember
INTRODUCTION: Penile size has long been an important fixation in men's lives. On the one hand, a smaller penis has been associated with anxiety and apprehension; on the other hand, a larger penis has generally been related to virility and strength. These perceptions predominate during an erection, when penile size is representative of a man's masculinity. AIM: To assess adult penile length and summarize average penile length assessments from the literature; analyze how various urologic diseases and therapies affect penile length and volume; and review how surgical treatments for Peyronie's disease, penile prosthesis implantation, and radical prostatectomy can affect penile size to appropriately counsel patients seeking such therapies and set realistic goals for patients...
December 27, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29288008/usage-and-survival-implications-of-surgical-staging-of-inguinal-lymph-nodes-in-intermediate-to-high-risk-clinical-localized-penile-cancer-a-propensity-score-matched-analysis
#9
Solomon L Woldu, Bo Ci, Ryan C Hutchinson, Laura-Maria Krabbe, Nirmish Singla, Niccolo M Passoni, Timothy N Clinton, Ganesh V Raj, David S Miller, Arthur I Sagalowsky, Yair Lotan, Yang Xie, Vitaly Margulis, Aditya Bagrodia
OBJECTIVES: To evaluate the usage of surgical staging of inguinal lymph nodes (SSILNs) in the United States for intermediate to high-risk, clinically localized penile squamous cell cancer (SCC), to explore patient and hospital factors associated with omission of this staging, and to evaluate the effect on survival. PATIENTS AND METHODS: Retrospective, observational study using the National Cancer Database from 2004 to 2014 of 1,689 men diagnosed with pT1b-T3, cN0 penile SCC, who by current guidelines should receive SSILNs-either by inguinal lymph node (ILN) dissection or sentinel node biopsy...
December 26, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29285831/proposal-for-reclassification-of-n-staging-systems-in-penile-cancer-patients-based-on-number-of-positive-lymph-nodes
#10
Zhiyong Li, Shengjie Guo, Zhiming Wu, Hui Han, Zaishang Li, Yanjun Wang, Jieping Chen, Chuangzhong Deng, Zike Qin, Zhuowei Liu, Yonghong Li, Dong Chen, Fangjian Zhou, Kai Yao
In the present study, we aim to compare the rationality of proposed N classification based on the number of metastatic lymph nodes (LNs) with the current one. A total of 509 penile cancer patients at our institute were analyzed. Univariable and multivariable statistical analyses were used to assess cancer-specific survival (CSS) in two staging systems. Harrell's concordance index was applied to evaluate predictive accuracy of the current and proposed N classification in predicting CSS. We propose a new classification: pN1 (metastasis in 1-2 regional LNs), pN2 (metastasis in 3 regional LNs, or three or fewer regional lymph nodes with extranodal extension), and pN3 (metastasis in 4 or more regional LNs)...
December 29, 2017: Cancer Science
https://www.readbyqxmd.com/read/29281853/racial-disparity-and-survival-outcomes-between-african-american-and-caucasian-men-with-penile-cancer
#11
Chad R Ritch, Nachiketh Soodana Prakash, Nicola Pavan, Raymond R Balise, Maria Camila Velasquez, Mahmoud Alameddine, Desmond Y Adamu, Sanoj Punnen, Dipen J Parekh, Mark L Gonzalgo
OBJECTIVE: To determine whether there was a survival difference for AAM versus CM with penile squamous cell carcinoma (pSCC), particularly in locally advanced and metastatic cases where disease mortality is highest. METHODS: Using the Florida Cancer Data System, we identified men with pSCC from 2005 to 2013. We compared age, follow-up, stage, race, and treatment type between AAM and CM. We performed Kaplan-Meier analysis for overall survival (OS) between AAM and CM for all stages, and for those with locally advanced and metastatic disease...
December 27, 2017: BJU International
https://www.readbyqxmd.com/read/29280463/cavernous-nerve-injury-by-radiation-therapy-may-potentiate-erectile-dysfunction-in-rats
#12
Javed Mahmood, Caroline Q Connors, Allen A Alexander, Radmila Pavlovic, Santanu Samanta, Sandrine Soman, Hotaka Matsui, Nikolai A Sopko, Trinity J Bivalacqua, Daniel Weinreich, Cheng-Ying Ho, John Eley, Amit Sawant, Isabel L Jackson, Zeljko Vujaskovic
PURPOSE/OBJECTIVES: Radiation-induced erectile-dysfunction (RiED) is one of the most common side effects of radiation therapy (RT) and significantly reduces the quality of life (QoL) of cancer patients. Approximately 50% of prostate cancer patients experience RiED within 3 to 5 years after completion of RT. A series of vascular, muscular, and neurogenic injuries after prostate RT lead to RiED; however, the precise role of RT-induced neurogenic injury in RiED has not been fully established...
November 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29275049/the-multiple-slit-technique-must-for-penile-length-and-girth-restoration
#13
Paulo H Egydio, Franklin E Kuehhas
BACKGROUND: Patients with severe erectile dysfunction (ED) and penile size issues, especially seen in Peyronie's disease (PD), are candidates for more invasive penile prosthesis insertion techniques that aim for penile length and girth reconstruction. AIM: To present the feasibility and safety of penile length and girth restoration based on the so-called multiple-slit technique (MUST) for patients with severe ED and significant penile shortening with or without PD...
December 20, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29259207/dickkopf2-rescues-erectile-function-by-enhancing-penile-neurovascular-regeneration-in-a-mouse-model-of-cavernous-nerve-injury
#14
Kalyan Ghatak, Guo Nan Yin, Min-Ji Choi, Anita Limanjaya, Nguyen Nhat Minh, Jiyeon Ock, Kang-Moon Song, Dong Hyuk Kang, Young-Guen Kwon, Ho Min Kim, Ji-Kan Ryu, Jun-Kyu Suh
Penile erection is a neurovascular event and neurologic or vascular disturbances are major causes of erectile dysfunction (ED). Radical prostatectomy for prostate cancer not only induces cavernous nerve injury (CNI) but also results in cavernous angiopathy, which is responsible for poor responsiveness to oral phosphodiesterase-5 inhibitors. Dickkopf2 (DKK2) is known as a Wnt signaling antagonist and is reported to promote mature and stable blood vessel formation. Here, we demonstrated in CNI mice that overexpression of DKK2 by administering DKK2 protein or by using DKK2-Tg mice successfully restored erectile function: this recovery was accompanied by enhanced neural regeneration through the secretion of neurotrophic factors, and restoration of cavernous endothelial cell and pericyte content...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29250197/antiangiogenic-therapies-in-urogenital-malignancies-fiction-or-fact
#15
REVIEW
Friederike Haidl, David Pfister, Axel Heidenreich, Isabel Heidegger
The use of antiangiogenic agents in cancer therapy has become an attractive target in oncological research. However, concerning the uro-oncological field, current guidelines only recommend the use of antiangiogenic agents in metastatic renal cell cancer. Yet in recent years, several approaches for sequential treatment with angiogenesis inhibitors in other urogenital malignancies apart from renal cell cancer are ongoing. Thus, the present review article aims to provide an overview about clinical studies with antiangiogenic agents in prostate-, bladder-, testicular-, as well as penile cancer patients...
2017: Memo
https://www.readbyqxmd.com/read/29248557/differences-in-survival-by-receipt-of-lymph-node-dissection-in-patients-with-invasive-penile-cancer-results-from-the-national-cancer-database
#16
Andres F Correa, Elizabeth Handorf, Shreyas S Joshi, Daniel M Geynisman, Alexander Kutikov, David Y Chen, Robert G Uzzo, Rosalia Viterbo, Richard E Greenberg, Marc C Smaldone
BACKGROUND: Inguinal lymphadenectomy (I-LND) remains underutilized in patients with invasive penile cancer. Using a large national cancer registry, we assessed temporal trends in I-LND utilization and evaluated the impact of I-LND on the survival in patients in whom I-LND is an absolute indication per NCCN guidelines (T1b-4 N0/x-1). METHODS: The National Cancer Database (NCDB) was queried for all non-metastatic penile patients with T1b-4 N0/X-N1 squamous cell carcinoma of the penis from 2004-2014...
December 14, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29245993/comparison-of-efficacy-between-brachytherapy-and-penectomy-in-patients-with-penile-cancer-a-meta-analysis
#17
Xiheng Hu, Jianghai Huang, Sailan Wen, Jun Fu, Minfeng Chen
We conducted a meta-analysis to compare the efficacy of brachytherapy and penectomy in patients with penile cancer. We searched the published articles in the PubMed, Web of Science, China National Knowledge Infrastructure, and Wanfang databases up to March 20, 2017. Twenty-two studies entered the final analyses. We used five-year overall survival rate, five-year local control rate, disease-free progression and lymph node positive rate to assess the efficacy. The meta-analysis found that patients who received penectomy had higher five-year local control rate (85% vs 80%, odds ratio = 0...
November 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/29241310/indocyanine-green-fluorescence-guided-sentinel-lymph-node-identification-in-urologic-cancers-a-systematic-review-and-meta-analysis
#18
Fouad Aoun, Simone Albisinni, Marc Zanaty, Toufic Hassan, Gunter Janetschek, Roland van Velthoven
INTRODUCTION: To date, bilateral pelvic lymph node dissection (PLND) represents the most accurate and reliable staging procedure for the detection of lymph node invasion in prostate cancer and bladder cancer. However, the procedure is not devoid of complications. In this field, Indocyanine green fluorescence-guided sentinel lymph node (SLN) identification is an emerging and promising technique, as accurate staging of urologic cancer could be enhanced by a thorough evaluation of the sentinel lymph nodes...
December 14, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29239406/erectile-dysfunction-following-cancer-therapy-is-there-a-role-for-penile-rehabilitation
#19
EDITORIAL
Jason R Kovac
No abstract text is available yet for this article.
November 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29238667/penile-prosthesis-in-the-management-of-erectile-dysfunction-following-cancer-therapy
#20
REVIEW
Pranav Dadhich, Mark Hockenberry, E Will Kirby, Larry Lipshultz
Erectile dysfunction (ED) is a common problem in older men and occurs with even greater frequency following the treatment of pelvic malignancies. Inflatable penile prosthesis (IPP) implantation is a safe and effective form of definitive ED treatment for those men who fail more conservative measures, and it can be used with similar outcomes in men following cancer therapy. Although many of these men remain dissatisfied with other therapeutic options for ED, IPPs are underutilized in this population. This review will discuss the current practice patterns, outcomes and nuances to surgical technique regarding the use of IPPs in patients with ED following cancer therapy...
November 2017: Translational Andrology and Urology
keyword
keyword
3130
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"