Ângelo Antônio Oliveira Silva, Ayla Araújo Lima, Larissa de Carvalho Medrado Vasconcelos, Rosângela Andrade de Almeida, Natália Erdens Maron de Freitas, Fernanda Lopes Habib, Talita Andrade Oliva, Miralba Freire de Carvalho Ribeiro da Silva, Isadora Cristina de Siqueira, Fred Luciano Neves Santos
There are a variety of nontreponemal test (NTT) and treponemal test (TT) kits for the serologic diagnosis of syphilis. Because of the complexity of the infection (multiple clinical stages) and the different antigens used in these kits, a systematic evaluation of the accuracy of the currently available commercial tests is warranted. Our objective was to evaluate the performance of commercially available tests for the diagnosis of syphilis infection. In this study, we analyzed one NTT (Venereal Disease Research Laboratory [VDRL] test, Wiener Laboratories, Rosario, Argentina) and two TTs (fluorescent treponemal antibody absorption [FTA-ABS] test, Euroimmun, Lübeck, Germany, and syphilis recombinant ELISA v...
April 9, 2024: American Journal of Tropical Medicine and Hygiene