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https://www.readbyqxmd.com/read/28820347/association-between-eye-diagnosis-and-positive-syphilis-test-results-in-a-large-urban-sexually-transmitted-infection-primary-care-clinic-population
#1
Ann-Marie Lobo, Yan Gao, Laura Rusie, Magda Houlberg, Supriya D Mehta
In 2015, the Centers for Disease Control and Prevention (CDC) and the American Academy of Ophthalmology (AAO) released clinical advisories on rising cases of ocular syphilis. We examined the association between eye disease and syphilis infection among primary care and sexually transmitted infection (STI) clinic patients attending an urban lesbian, gay, bisexual, transgender (LGBT) health center. We conducted a retrospective medical record review of all patients who underwent syphilis testing at Howard Brown Health between 1 January 2010 and 31 December 2015...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28814603/single-nucleotide-polymorphisms-of-the-high-affinity-igg-receptor-fc%C3%AE-ri-reduce-immune-complex-binding-and-downstream-effector-functions
#2
Arianne M Brandsma, Toine Ten Broeke, Evelien van Dueren den Hollander, Thomas G Caniels, Tineke Kardol-Hoefnagel, Jürgen Kuball, Jeanette H W Leusen
Binding of IgG Abs to FcγRs on immune cells induces FcγR cross-linking that leads to cellular effector functions, such as phagocytosis, Ab-dependent cellular cytotoxicity, and cytokine release. However, polymorphisms in low affinity FcγRs have been associated with altered avidity toward IgG, thereby substantially impacting clinical outcomes of multimodular therapy when targeting cancer or autoimmune diseases with mAbs as well as the frequency and severity of autoimmune diseases. In this context, we investigated the consequences of three nonsynonymous single nucleotide polymorphisms (SNPs) for the high affinity receptor for IgG, FcγRI...
August 16, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28813585/association-of-general-surgery-resident-remediation-and-program-director-attitudes-with-resident-attrition
#3
Alexander C Schwed, Steven L Lee, Edgardo S Salcedo, Mark E Reeves, Kenji Inaba, Richard A Sidwell, Farin Amersi, Chandrakanth Are, Tracey D Arnell, Richard B Damewood, Daniel L Dent, Timothy Donahue, Jeffrey Gauvin, Thomas Hartranft, Garth R Jacobsen, Benjamin T Jarman, Marc L Melcher, John D Mellinger, Jon B Morris, Mark Nehler, Brian R Smith, Mary Wolfe, Amy H Kaji, Christian de Virgilio
Importance: Previous studies of resident attrition have variably included preliminary residents and likely overestimated categorical resident attrition. Whether program director attitudes affect attrition has been unclear. Objectives: To determine whether program director attitudes are associated with resident attrition and to measure the categorical resident attrition rate. Design, Setting, and Participants: This multicenter study surveyed 21 US program directors in general surgery about their opinions regarding resident education and attrition...
August 16, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28803763/laboratory-simulations-of-the-mixed-solvent-extraction-recovery-of-dominate-polymers-in-electronic-waste
#4
Yi-Bo Zhao, Xu-Dong Lv, Wan-Dong Yang, Hong-Gang Ni
The recovery of four dominant plastics from electronic waste (e-waste) using mixed solvent extraction was studied. The target plastics included polycarbonate (PC), polystyrene (PS), acrylonitrile butadiene styrene (ABS), and styrene acrylonitrile (SAN). The extraction procedure for multi-polymers at room temperature yielded PC, PS, ABS, and SAN in acceptable recovery rates (64%, 86%, 127%, and 143%, respectively, where recovery rate is defined as the mass ratio of the recovered plastic to the added standard polymer)...
August 10, 2017: Waste Management
https://www.readbyqxmd.com/read/28801580/immune-responses-against-helicobacter-pylori-specific-antigens-differentiate-relapsing-remitting-from-secondary-progressive-multiple-sclerosis
#5
Georgios Efthymiou, Efthymios Dardiotis, Christos Liaskos, Emmanouela Marou, Vana Tsimourtou, Eirini I Rigopoulou, Thomas Scheper, Alexandros Daponte, Wolfgang Meyer, Lazaros I Sakkas, Georgios Hadjigeorgiou, Dimitrios P Bogdanos
To assess whether Helicobacter pylori (Hp) antibody (ab) reactivity against individual Hp antigens is pathogenetically relevant to multiple sclerosis (MS), we systematically investigated prevalence and clinical significance of abs against 14 immunodominant and subdominant Hp antigens by ELISA and immunoblotting in 139 consecutive MS patients with relapsing-remitting (RRMS, n = 102) or secondary progressive (SPMS, n = 37). Sera from 39 patients with Parkinson's disease (PD), 21 with Alzheimer's disease (ALZ) and 68 healthy controls (HCs), were also tested...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28801216/a-novel-process-for-separation-of-hazardous-poly-vinyl-chloride-from-mixed-plastic-wastes-by-froth-flotation
#6
Jianchao Wang, Hui Wang, Chongqing Wang, Lingling Zhang, Tao Wang, Long Zheng
A novel method, calcium hypochlorite (CHC) treatment, was proposed for separation of hazardous poly(vinyl chloride) (PVC) plastic from mixed plastic wastes (MPWs) by froth flotation. Flotation behavior of single plastic indicates that PVC can be separated from poly(ethylene terephthalate) (PET), poly(acrylonitrile-co-butadiene-co-styrene) (ABS), polystyrene (PS), polycarbonate (PC) and poly(methyl methacrylate) (PMMA) by froth flotation combined with CHC treatment. Mechanism of CHC treatment was examined by contact angle measurement, scanning electron microscopy, Fourier transform infrared and X-ray photoelectron spectroscopy...
August 8, 2017: Waste Management
https://www.readbyqxmd.com/read/28797000/new-molecular-biological-and-immunological-agents-inducing-hypophysitis
#7
Anna Angelousi, Eleftherios Chatzellis, Gregory Kaltsas
<br>Hypophysitis is a relatively rare disease that exerts a strong autoimmune component encompassing different aetiologies. Immunomodulatory drugs, such as interferon-α, are known to rarely induce hypophysitis. In recent years a large number of new biological and immunomodulatory agents have been introduced into clinical practice. Although immune suppressing agents used for the treatment of autoimmune disorders only rarely are associated with hypophysitis, it is commonly encountered with immunomodulatory agents used for the treatment of cancer...
August 8, 2017: Neuroendocrinology
https://www.readbyqxmd.com/read/28796643/monte-carlo-and-experimental-determination-of-correction-factors-for-gamma-knife-perfexion-small-field-dosimetry-measurements
#8
Emmanouil Zoros, Argyris S Moutsatsos, Eleftherios P Pappas, Evangelos Georgiou, Georgios Kollias, Pantelis Karaiskos, Evaggelos Pantelis
Detector-, field size- and machine-specific correction factors are required for precise dosimetry measurements in small and non-standard photon fields. In this work, Monte Carlo (MC) simulation techniques were used to calculate the correction factors for a series of ionization chambers, a synthetic microDiamond and diode dosimeters, used for reference and/or output factor (OF) measurements in the Gamma Knife Perfexion photon fields. Calculations were performed for the Solid Water (SW) and ABS plastic phantoms, as well as for a water phantom of the same geometry...
August 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28793962/simultaneous-extraction-and-concentration-of-water-pollution-tracers-using-ionic-liquid-based-systems
#9
Teresa B V Dinis, Helena Passos, Diana L D Lima, Ana C A Sousa, João A P Coutinho, Valdemar I Esteves, Mara G Freire
Human activities are responsible for the release of innumerous substances into the aquatic environment. Some of these substances can be used as pollution tracers to identify contamination sources and to prioritize monitoring and remediation actions. Thus, their identification and quantification are of high priority. However, due to their presence in complex matrices and at significantly low concentrations, a pre-treatment/concentration step is always required. As an alternative to the currently used pre-treatment methods, mainly based on solid-phase extractions, aqueous biphasic systems (ABS) composed of ionic liquids (ILs) and K3C6H5O7 are here proposed for the simultaneous extraction and concentration of mixtures of two important pollution tracers, caffeine (CAF) and carbamazepine (CBZ)...
July 29, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28792915/fast-rbc-loading-by-fluorescent-antibodies-and-nuclei-staining-dye-and-their-potential-bioanalytical-applications
#10
Mohamed K Al-Essa, Susanne Melzer, Attila Tarnok, Kamal A Hadidi, Mohammed El-Khateeb
This study was designed to load different antibodies (Abs) and a fluorescent dye onto the red blood cell (RBC) surface. We have used fluorescein isothiocyanate (FITC)-conjugate anti-human Ab, CD22-PE (B-cell marker-phycoerythrin Ab), and 4',6-diamidino-2-phenylindole (DAPI) for insertion over the RBC surface. In a first step, conjugation experiments were performed: in dimethyl sulfoxide (DMSO), RBCs were conserved and modified by succinic anhydride to create an additional -COOH group, and then activated with 3-(3-dimethylaminopropyl)carbodiimide-N-hydroxysuccinimide (EDC-NHS) in 2-(N-morpholino) ethanesulfonic acid hydrate buffer for insertion of labeled Abs or DAPI...
August 9, 2017: Zeitschrift Für Naturforschung. C, A Journal of Biosciences
https://www.readbyqxmd.com/read/28791995/-morphological-and-immunohistochemical-features-of-severe-gastric-dysplasia-and-early-gastric-cancer
#11
L M Mikhaleva, A E Biryukov
AIM: to investigate the morphological and immunohistochemical features of severe gastric dysplasia (SGD) and early gastric cancer (EGC). MATERIAL AND METHODS: The fragments of gastric tumor tissue with adjacent mucosal portions from 50 patients aged from 34 to 79 years (mean age 63.8 years), which had been removed during organ-sparing endoscopic surgery, were histologically, histochemical, and immunohistochemically (IHC) examined. RESULTS: In EGC, there was a preponderance of intestinal-type cancer; the adjacent mucosal areas showed foci of SGD and colonic metaplasia in 100%...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28791977/comparative-evaluation-of-ankaferd-blood-stopper-ferric-sulfate-and-formocresol-as-pulpotomy-agent-in-primary-teeth-a-clinical-study
#12
B Ozmen, S Bayrak
AIM: The aim of the study was to provide a comparative evaluation of the clinical and radiographic success of Ankaferd blood stopper (ABS), formocresol (FC), and ferric sulfate (FS) as pulpotomy agent in primary teeth. SETTINGS AND DESIGN: This is a clinical study. MATERIALS AND METHODS: A total of 45 primary mandibular molar teeth in 26 children aged 6-9 were selected for the study. Teeth were randomly divided into three groups according to the pulpotomy agents (ABS, FC, FS)...
July 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28791693/atypical-antipsychotics-for-disruptive-behaviour-disorders-in-children-and-youths
#13
REVIEW
Jik H Loy, Sally N Merry, Sarah E Hetrick, Karolina Stasiak
BACKGROUND: This is an update of the original Cochrane Review, last published in 2012 (Loy 2012). Children and youths with disruptive behaviour disorders may present to health services, where they may be treated with atypical antipsychotics. There is increasing usage of atypical antipsychotics in the treatment of disruptive behaviour disorders. OBJECTIVES: To evaluate the effect and safety of atypical antipsychotics, compared to placebo, for treating disruptive behaviour disorders in children and youths...
August 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28791302/in-vitro-laser-treatment-platform-construction-with-dental-implant-thread-surface-on-bacterial-adhesion-for-peri-implantitis
#14
Hsien-Nan Kuo, Hsiang-I Mei, Tung-Kuan Liu, Tse-Ying Liu, Lun-Jou Lo, Chun-Li Lin
This study constructs a standard in vitro laser treatment platform with dental implant thread surface on bacterial adhesion for peri-implantitis at different tooth positions. The standard clinical adult tooth jaw model was scanned to construct the digital model with 6 mm bone loss depth on behalf of serious peri-implantitis at the incisor, first premolar, and first molar. A cylindrical suite connected to the implant and each tooth root in the jaw model was designed as one experimental unit set to allow the suite to be replaced for individual bacterial adhesion...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28789516/aerosol-emissions-from-fuse-deposition-modeling-3d-printers-in-a-chamber-and-in-real-indoor-environments
#15
Marina Eller Vance, Valerie Pegues, Schuyler Van Montfrans, Weinan Leng, Linsey C Marr
Three-dimensional (3D) printers are known to emit aerosols, but questions remain about their composition and the fundamental processes driving emissions. The objective of this work was to characterize aerosol emissions from the operation of a fuse-deposition modeling 3D printer. We modeled the time- and size-resolved emissions of submicron aerosols from the printer in a chamber study, gained insight into the chemical composition of emitted aerosols using Raman spectroscopy, and measured potential for exposure to aerosols generated by 3D printers under real-use conditions in a variety of indoor environments...
August 8, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28783104/exosomes-and-other-extracellular-vesicles-in-hpv-transmission-and-carcinogenesis
#16
REVIEW
David Guenat, François Hermetet, Jean-Luc Prétet, Christiane Mougin
Extracellular vesicles (EVs), including exosomes (Exos), microvesicles (MVs) and apoptotic bodies (ABs) are released in biofluids by virtually all living cells. Tumor-derived Exos and MVs are garnering increasing attention because of their ability to participate in cellular communication or transfer of bioactive molecules (mRNAs, microRNAs, DNA and proteins) between neighboring cancerous or normal cells, and to contribute to human cancer progression. Malignant traits can also be transferred from apoptotic cancer cells to phagocytizing cells, either professional or non-professional...
August 7, 2017: Viruses
https://www.readbyqxmd.com/read/28777668/therapeutic-tumor-control-of-her2-dna-vaccines-is-achieved-by-an-alteration-of-tumor-cells-and-tumor-microenvironment-by-gemcitabine-and-anti-gr-1-ab-treatment-in-a-her2-expressing-tumor-model
#17
Sayyed Nilofar Danishmalik, Jeong-Im Sin
Therapeutic control of tumors is challenging as they tend to alter their biological functions and microenvironment. In a CT26/HER2 tumor model, HER2 DNA vaccines and even anti-PD-L1 Abs failed to display antitumor therapeutic activity while inducing Ag-specific cytotoxic T lymphocyte (CTL) activity. To clarify this contradictory finding, we selected tumor cells (CT26/HER2-1) from one tumor-bearing animal in the therapeutic model. CT26/HER2-1 cells behaved similar to wild-type CT26/HER2 cells in their HER2 expression, immune cell stimulation for IFN-γ production, and antitumor immune sensitivity...
August 4, 2017: DNA and Cell Biology
https://www.readbyqxmd.com/read/28774019/analytical-modelling-and-optimization-of-the-temperature-dependent-dynamic-mechanical-properties-of-fused-deposition-fabricated-parts-made-of-pc-abs
#18
Omar Ahmed Mohamed, Syed Hasan Masood, Jahar Lal Bhowmik
Fused deposition modeling (FDM) additive manufacturing has been intensively used for many industrial applications due to its attractive advantages over traditional manufacturing processes. The process parameters used in FDM have significant influence on the part quality and its properties. This process produces the plastic part through complex mechanisms and it involves complex relationships between the manufacturing conditions and the quality of the processed part. In the present study, the influence of multi-level manufacturing parameters on the temperature-dependent dynamic mechanical properties of FDM processed parts was investigated using IV-optimality response surface methodology (RSM) and multilayer feed-forward neural networks (MFNNs)...
November 4, 2016: Materials
https://www.readbyqxmd.com/read/28773244/investigations-for-thermal-and-electrical-conductivity-of-abs-graphene-blended-prototypes
#19
Rupinder Singh, Gurleen S Sandhu, Rosa Penna, Ilenia Farina
The thermoplastic materials such as acrylonitrile-butadiene-styrene (ABS) and Nylon have large applications in three-dimensional printing of functional/non-functional prototypes. Usually these polymer-based prototypes are lacking in thermal and electrical conductivity. Graphene (Gr) has attracted impressive enthusiasm in the recent past due to its natural mechanical, thermal, and electrical properties. This paper presents the step by step procedure (as a case study) for development of an in-house ABS-Gr blended composite feedstock filament for fused deposition modelling (FDM) applications...
July 31, 2017: Materials
https://www.readbyqxmd.com/read/28772180/exploring-the-mechanism-and-kinetics-of-fe-cu-ag-trimetallic-particles-for-p-nitrophenol-reduction
#20
Yue Yuan, Donghai Yuan, Yunhong Zhang, Bo Lai
Preparation conditions of Fe-Cu-Ag trimetallic particles were optimized by single-factor and response surface methodology (RSM) batch experiments to obtain high-reactive Fe(0)-based materials for p-nitrophenol (PNP) removal. Under the optimal conditions (i.e., Fe(0) dosage of 34.86 g L(-1), theoretical Cu mass loading of 81.87 mg Cu/g Fe, theoretical Ag mass loading of 1.15 mg Ag/g Fe, and preparation temperature of 52.1 °C), the actual rate constant (kobs) of PNP reduction in 5 min was 1.64 min(-1), which shows a good agreement between the model prediction (1...
July 12, 2017: Chemosphere
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