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pregnancy heart disease

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https://www.readbyqxmd.com/read/29774566/influence-of-sex-and-pregnancy-on-survival-in-patients-admitted-with-heart-failure-data-from-a-prospective-multicenter-registry
#1
Manuel Martínez-Sellés, Pablo Díez-Villanueva, Jesús Álvarez-Gracía, Andreu Ferrero-Gregori, Miquel Vives-Borrás, Fernando Worner, Alfredo Bardají, Juan F Delgado, Rafael Vázquez, José R González-Juanatey, Francisco Fernández-Aviles, Juan Cinca
BACKGROUND: Female sex is an independent predictor of better survival in patients with heart failure but the mechanism of this association is unknown. On the other hand, pregnancies have a strong influence in the cardiovascular system. HYPOTHESIS: Sex and previous gestations might have a prognostic impact on one-year mortality in patients admitted with heart failure. METHODS: Observational prospective consecutive multicenter registry of 1831 patients (756 women [41...
May 17, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29767811/peripartum-cardiomyopathy
#2
T Koenig, D Hilfiker-Kleiner, J Bauersachs
Peripartum cardiomyopathy (PPCM) is a rare and potentially life-threatening disease that occurs toward the end of pregnancy or in the months following delivery in previously heart-healthy women. The incidence varies widely depending on geographical region and ethnic background, with an estimated number of 1 in 1000-1500 pregnancies in Germany. The course of the disease ranges from mild forms with minor symptoms to severe forms with acute heart failure and cardiogenic shock. The understanding of the etiology of PPCM has evolved in recent years...
May 16, 2018: Herz
https://www.readbyqxmd.com/read/29762460/a-new-life-motherhood-after-heart-transplantation-a-single-center-experience-and-review-of-literature
#3
Francesca Macera, Lucia Occhi, Gabriella Masciocco, Marisa Varrenti, Maria Frigerio
BACKGROUND: Pregnancy after heart transplantation (HTx) may expose the recipient to hemodynamic and immunologic risks, and the newborn to toxic effects of immunosuppressive therapy. Adequate preconception counseling is crucial to identify optimal timing and to modify immunosuppressive therapy in order to minimize risks for both the mother and the fetus. METHOD: We describe our experience with 12 pregnancies occurred in 11 women who had undergone HTx at our center...
May 14, 2018: Transplantation
https://www.readbyqxmd.com/read/29762274/decomposing-medicaid-spending-during-health-system-reform-and-aca-expansion-evidence-from-oregon
#4
Stephanie Renfro, Stephan Lindner, K John McConnell
BACKGROUND: Expansion of the Medicaid program is likely to create new budgetary pressures at the state and federal levels, creating a need for greater understanding of how program dollars are allocated and what drives spending growth. OBJECTIVE: To characterize Oregon Medicaid expenditures across diseases and medical conditions, during periods of payment reform and coverage expansion. RESEARCH DESIGN: Decomposition of changes in Medicaid expenditures using a person-based allocation of spending across 50 diseases/medical conditions...
May 12, 2018: Medical Care
https://www.readbyqxmd.com/read/29755033/impact-of-a-history-of-hypertension-in-pregnancy-on-later-diagnosis-of-atrial-fibrillation
#5
Dawn C Scantlebury, Andrea G Kattah, Tracey L Weissgerber, Sanket Agarwal, Michelle M Mielke, Amy L Weaver, Lisa E Vaughan, Stanislav Henkin, Katherine Zimmerman, Virginia M Miller, Wendy M White, Sharonne N Hayes, Vesna D Garovic
BACKGROUND: Atrial fibrillation/flutter (AF) produces significant morbidity in women and is typically attributed to cardiac remodeling from multiple causes, particularly hypertension. Hypertensive pregnancy disorders (HPDs) are associated with future hypertension and adverse cardiac remodeling. We evaluated whether women with AF were more likely to have experienced a HPD compared with those without. METHODS AND RESULTS: A nested case-control study was conducted within a cohort of 7566 women who had a live or stillbirth delivery in Olmsted County, Minnesota between 1976 and 1982...
May 13, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29753320/adverse-effects-of-hif1a-mutation-and-maternal-diabetes-on-the-offspring-heart
#6
Radka Cerychova, Romana Bohuslavova, Frantisek Papousek, David Sedmera, Pavel Abaffy, Vladimir Benes, Frantisek Kolar, Gabriela Pavlinkova
BACKGROUND: Epidemiological studies show that maternal diabetes predisposes offspring to cardiovascular and metabolic disorders. However, the precise mechanisms for the underlying penetrance and disease predisposition remain poorly understood. We examined whether hypoxia-inducible factor 1 alpha, in combination with exposure to a diabetic intrauterine environment, influences the function and molecular structure of the adult offspring heart. METHODS AND RESULTS: In a mouse model, we demonstrated that haploinsufficient (Hif1a+/- ) offspring from a diabetic pregnancy developed left ventricle dysfunction at 12 weeks of age, as manifested by decreased fractional shortening and structural remodeling of the myocardium...
May 12, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29749620/peripartum-cardiomyopathy-a-systematic-review-of-the-literature
#7
REVIEW
Zain Ul Abideen Asad, Mirwais Maiwand, Fahmi Farah, Tarun W Dasari
Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure. It is defined as cardiomyopathy that develops in the last month of pregnancy or within 5 months of the postpartum period without an identifiable cause. We conducted a systematic review of literature of prospective studies with a focus on echocardiographic and long-term clinical outcomes in PPCM. We searched MEDLINE and Embase up to October 1, 2017. Prospective studies (sample size ≥20) reporting all-cause mortality and follow-up duration of ≥1 year were included...
May 11, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29747730/maternal-congenital-heart-disease-in-pregnancy
#8
REVIEW
Megan E Foeller, Timothy M Foeller, Maurice Druzin
Congenital heart disease comprises most maternal cardiac diseases in pregnancy and is an important cause of maternal, fetal, and neonatal morbidity and mortality worldwide. Pregnancy is often considered a high-risk state for individuals with structural heart disease as a consequence of a limited ability to adapt to the major hemodynamic changes associated with pregnancy. Preconception counseling and evaluation are of utmost importance, as pregnancy is contraindicated in certain cardiac conditions. Pregnancy can be safely accomplished in most individuals with careful risk assessment before conception and multidisciplinary care throughout pregnancy and the postpartum period...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29747265/-effect-of-maternal-age-on-pregnancy-outcome-in-patients-with-structural-heart-disease
#9
Q Fu, J H Lin
Objective: To analyze the effect of maternal age on pregnancy outcome in patients with structural heart disease. Methods: Totally 986 patients diagnosed with structural heart disease who had their delivery at Renji Hospital from January 1st, 2003 to December 31st, 2016 were divided into 5 groups according to maternal age. Sixteen (1.6%) were in age group <20 years, 204 (20.7%) were in age group 20-24 years, 461 (46.8%) were in age group 25-29 years, 222 (22.5%) was in age group 30-34 years and 83 (8.4%) was in age group ≥35 years...
April 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29744129/contributing-factors-of-pregnant-women-s-beliefs-towards-mode-of-delivery-a-cross-sectional-study-from-iran
#10
Fereshteh Zamani-Alavijeh, Marzieh Araban, Akbar Hassanzadeh, Khadije Makhouli
Background: Delivery is a critical event in every woman's life. Under some medical conditions, women sometimes undergo a cesarean section to save the life of themselves and their infant. Understanding the factors associated with choosing the type of delivery leads to more effective health interventions and the promotion of maternal and newborn health. The aim of this study is to determine contributing factors in pregnant women's beliefs toward the mode of delivery in a sample of women referring to Hojatieh Hospital in Isfahan, Iran...
2018: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/29744016/congenital-heart-disease-and-reproductive-risk-an-overview-for-obstetricians-cardiologists-and-primary-care-providers
#11
REVIEW
Sabrina Phillips, Michael Pirics
Patients with congenital heart disease have improved survival rates, and most patients are now expected to survive into adulthood. This improved survival has resulted in increasing numbers of women with congenital heart disease who are of childbearing age. This patient population requires specialized advice on contraception and pregnancy risk. Understanding the unique challenges this population presents is key to providing appropriate care.
October 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29720579/congenital-esophageal-atresia-and-microtia-in-a-newborn-secondary-to-mycophenolate-mofetil-exposure-during-pregnancy-a-case-report-and-review-of-the-literature
#12
Musaed Mohammed Alsebayel, Faisal Abdulrahman Abaalkhail, Faisal Mohammed Alsebayel, Dema A Alissa, Ahmed Hamdan Al-Jedai, Hussien Elsiesy
BACKGROUND Mycophenolate mofetil (MMF) is one of the most commonly prescribed drugs to prevent organ transplant rejection in combination with calcineurin inhibitors and steroids. It has a different toxicity profile than tacrolimus and cyclosporine.  Gastrointestinal tract disturbances are the most common adverse effects. The use of MMF in pregnant women, however, holds great risk of miscarriage and fetal development defects such as external ear malformation, ocular anomalies, cleft lip and palate, and abnormality of distal limbs, heart, esophagus, and kidneys...
May 3, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29703438/etiologies-predictors-and-economic-impact-of-30-day-readmissions-among-patients-with-peripartum-cardiomyopathy
#13
Mahek Shah, Pradhum Ram, Kevin Bryan Lo, Soumya Patnaik, Brijesh Patel, Byomesh Tripathi, Shantanu Patil, Marvin Lu, Ulrich P Jorde, Vincent M Figueredo
Peripartum cardiomyopathy (PPCM) is a pregnancy-associated cause of heart failure. Given the significant impact of heart failure on healthcare, we sought to identify etiologies and predictive factors for readmission in PPCM. We queried the 2013 to 2014 National Readmissions Database to identify patients admitted with a diagnosis of PPCM. Patients who were readmitted within 30 days were evaluated to identify etiologies and predictors of readmission. We identified 6,977 index admissions with PPCM. Of the 6,880 (98...
March 29, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29702718/a-critical-review-on-obstetric-follow-up-of-women-affected-by-systemic-lupus-erythematosus
#14
Danilo Eduardo Abib Pastore, Maria Laura Costa, Mary Angela Parpinelli, Fernanda Garanhani Surita
OBJECTIVE:  To review the existing recommendations on the prenatal care of women with systemic lupus erythematosus (SLE), based on currently available scientific evidence. METHODS:  An integrative review was performed by two independent researchers, based on the literature available in the MEDLINE (via PubMed), EMBASE and The Cochrane Library databases, using the medical subject headings (MeSH) terms "systemic lupus erythematosus" AND "high-risk pregnancy" OR "prenatal care...
April 27, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29696409/valvular-heart-disease-and-pregnancy
#15
REVIEW
Emily S Lau, Nandita S Scott
With improving reproductive assistive technologies, advancing maternal age, and improved survival of patients with congenital heart disease, valvular heart disease has become an important cause of morbidity and mortality in pregnant women. In general, stenotic lesions, even those in the moderate range, are poorly tolerated in the face of hemodynamic changes of pregnancy. Regurgitant lesions, however, fare better due to the physiologic afterload reduction that occurs. Intervention on regurgitant valve preconception follows the same principles as a non-pregnant population...
April 26, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29694606/cardiovascular-abnormalities-in-patients-with-oral-cleft-a-clinical-electrocardiographic-echocardiographic-study
#16
Gisele C P Leite, Marcela A G Ururahy, João F Bezerra, Valéria M G D M Lima, Maria I F Costa, Sandra S C Freire, André D Luchessi, Jussara M C Maia, Maria E F Brito, Vera L Gil-da-Silva-Lopes, Adriana A Rezende
OBJECTIVES: The present study aims to describe the clinical, electrocardiographic, and echocardiographic cardiological findings in a group of patients with oral clefts. METHODS: This is a prospective cross-sectional study on 70 children (age range from 13 days to 19 years) with oral clefts who attended the multidisciplinary program of a university hospital from March 2013 to September 2014. The patients were evaluated by a pediatric cardiologist and underwent detailed anamnesis, physical examination, electrocardiogram, and echocardiogram...
2018: Clinics
https://www.readbyqxmd.com/read/29668027/heart-transplant-in-children-what-a-primary-care-provider-needs-to-know
#17
Swati Sehgal, Emily Shea, Lauren Kelm, Deepak Kamat
Heart transplantation is offered to children with heart failure that is not amenable to medical or surgical therapy. Indications for heart transplant include unrepairable congenital heart disease, failed palliation of congenital heart disease, and cardiomyopathies. There has been tremendous progress in this field since the first heart transplant was performed in 1967. Each year, approximately 500 pediatric heart transplants take place worldwide. Pediatric heart transplant survivors are living longer with their initial transplant...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29657059/pregnancy-in-women-with-congenital-heart-disease-need-for-new-techniques-in-hemodynamic-monitoring
#18
EDITORIAL
L Baris, J W Roos-Hesselink
No abstract text is available yet for this article.
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29657057/ventricular-efficiency-in-pregnant-women-with-congenital-heart-disease
#19
Jun Muneuchi, Keiko Yamasaki, Mamie Watanabe, Azusa Fukumitsu, Takeshi Kawakami, Hiromasa Nakahara, Kunitaka Joo
BACKGROUNDS: Pregnant women with congenital heart disease (CHD) are at risk of cardiovascular events during pregnancy as well as postpartum. The aim of our study is to address the feasibility of echocardiography-derived ventricular-arterial coupling during pregnancy and postpartum among women with CHD. METHODS: In 31 pregnant women with CHD, we performed serial echocardiography at the first and third trimesters, early and late postpartum. The indices of contractility (single-beat determined end-systolic elastance, Eesab ) and afterload (effective arterial elastance, Ea) were approximated on the basis of the systemic blood pressure and systemic ventricular volume...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29626099/incidence-risk-factors-and-clinical-characteristics-of-peripartum-cardiomyopathy-in-south-korea
#20
Sunki Lee, Geum Joon Cho, Geun U Park, Log Young Kim, Tae-Seon Lee, Do Young Kim, Suk-Won Choi, Jong-Chan Youn, Seong Woo Han, Kyu-Hyung Ryu, Jin Oh Na, Cheol Ung Choi, Hong Seog Seo, Eung Ju Kim
BACKGROUND: Peripartum cardiomyopathy (PPCM) is a rare disorder associated with pregnancy that can lead to life-threatening conditions. The incidence and clinical characteristics of this condition remain poorly understood. METHODS AND RESULTS: We aimed to perform the first population-based study of PPCM in South Korea, using the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service. Patients who fulfilled predefined diagnostic criteria for PPCM from January 1, 2010, to December 31, 2012, were identified from International Classification of Diseases, Tenth Revision, Clinical Modification codes...
April 2018: Circulation. Heart Failure
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