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https://www.readbyqxmd.com/read/28527394/elucidation-of-penetration-enhancement-mechanism-of-emu-oil-using-ftir-microspectroscopy-at-emira-laboratory-of-sesame-synchrotron
#1
Randa S H Mansour, Alsayed A Sallam, Imad I Hamdan, Enam A Khalil, Ibraheem Yousef
It has been proposed that Emu oil possesses skin permeation-enhancing effect. This study aimed to address its possible penetration enhancement mechanism(s) using IR microscopy, in accordance with LPP theory. The penetration of Emu oil through the layers of human skin was accomplished by monitoring oil-IR characteristic feature at 3006cm(-1). The unsaturated components of Emu oil accumulated at about 270μm depth of skin surface. The interaction of Emu oil with lipid and protein constituents of SC was investigated in comparison with a commonly used enhancer, IPM...
May 12, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28526198/anthropogenic-contamination-of-portuguese-coastal-waters-during-the-bathing-season-assessment-using-caffeine-as-a-chemical-marker
#2
Paula Paíga, Cristina Delerue-Matos
Bathing water quality standards are based on international standards and legislations. However, in Europe, only the microbiological parameters are to be accomplished. Recent research has focused on chemical indicators that can determine human fecal contaminants in water. Therefore, the suitability of caffeine as a chemical marker of seawater pollution in the north Portuguese coastal area in the Atlantic Ocean during the bathing season was assessed in this study. The quality of water from the coasts of five cities was monitored...
May 17, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28523863/feasibility-of-near-infrared-transmittance-spectroscopy-to-predict-fatty-acid-composition-of-commercial-processed-meat
#3
Massimo De Marchi, Carmen L Manuelian, Sofia Ton, Martino Cassandro, Mauro Penasa
BACKGROUND: The new European Regulation 1169/2011 about nutrition declaration of food products compels to add saturated fatty acids, being voluntary to declare monounsaturated and polyunsaturated fatty acids. Therefore, industry is interested in more rapid, easy and less cost-effective analysis methods to accomplish the labelling regulation. This study aimed to evaluate the ability of near infrared transmittance spectroscopy (wavelengths between 850 and 1050 nm) to predict fatty acid (FA) composition of commercial processed meat samples (n = 310)...
May 19, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28521647/a-qualitative-investigation-of-lay-perspectives-of-diagnosis-and-self-management-strategies-employed-by-people-with-progressive-multiple-sclerosis
#4
Julia Frost, Jane Grose, Nicky Britten
This article explores how people with progressive multiple sclerosis give meaning to their experiences. It builds upon the self-management literature, which has captured the tension between the desire for retaining normalcy and the increasing burden of self-management associated with chronic disease progression. This repeat interview study is empirically grounded in 28 interviews with 14 people with progressive multiple sclerosis. We identified gender differences in diagnosis-seeking which impacted subsequent sense-making...
May 2017: Health (London)
https://www.readbyqxmd.com/read/28521600/quantitative-structure-activity-relationship-study-of-amide-mosquito-repellents
#5
P Wang, X Xu, S Liao, J Song, G Fan, S Chen, Z Wang
A quantitative structure-activity relationship (QSAR) study on 43 amide repellents was carried out by the heuristic method in order to reveal the correlations between molecular parameters of these amides and their repellency against Aedes aegypti. Sketches and optimizations of molecular structures were achieved by the Gaussian software package. Generation and screening of molecular parameters were accomplished using CODESSA 2.7.10 software. The leave-one-out method was applied for the model validation. The results showed that a four-descriptor QSAR model with r(2) of 0...
April 2017: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/28520947/synergistic-effect-of-spice-extracts-and-modified-atmospheric-packaging-towards-non-thermal-preservation-of-chicken-meat-under-refrigerated-storage
#6
M Sivarajan, U Lalithapriya, Peter Mariajenita, B Aafrin Vajiha, K Harini, D Madhushalini, M Sukumar
This study investigates the integrated approach of spice extracts and modified atmospheric packaging (MAP) chicken meat preservation. Specifically, extracts from clove (CL), cinnamon (CI) individually and in combination (3% w/w) along with MAP (30% CO2/70% N2 and 10% O2/30% CO2/60% N2) were used to increase the shelf life of fresh chicken meat stored at 4°C. The parameters evaluated as shelf life indications are microbiological (total viable count, Pseudomonas spp., lactic acid bacteria (LAB), and Enterobacteriaceae), physicochemical (pH, Lipid oxidation, color changes) and Sensory attributes...
May 17, 2017: Poultry Science
https://www.readbyqxmd.com/read/28516196/coupling-dynamics-in-speech-gestures-amplitude-and-rate-influences
#7
Pascal H H M van Lieshout
Speech is a complex oral motor function that involves multiple articulators that need to be coordinated in space and time at relatively high movement speeds. How this is accomplished remains an important and largely unresolved empirical question. From a coordination dynamics perspective, coordination involves the assembly of coordinative units that are characterized by inherently stable coupling patterns that act as attractor states for task-specific actions. In the motor control literature, one particular model formulated by Haken et al...
May 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28516175/tummytrials-a-feasibility-study-of-using-self-experimentation-to-detect-individualized-food-triggers
#8
Ravi Karkar, Jessica Schroeder, Daniel A Epstein, Laura R Pina, Jeffrey Scofield, James Fogarty, Julie A Kientz, Sean A Munson, Roger Vilardaga, Jasmine Zia
Diagnostic self-tracking, the recording of personal information to diagnose or manage a health condition, is a common practice, especially for people with chronic conditions. Unfortunately, many who attempt diagnostic self-tracking have trouble accomplishing their goals. People often lack knowledge and skills needed to design and conduct scientifically rigorous experiments, and current tools provide little support. To address these shortcomings and explore opportunities for diagnostic self-tracking, we designed, developed, and evaluated a mobile app that applies a self-experimentation framework to support patients suffering from irritable bowel syndrome (IBS) in identifying their personal food triggers...
May 2, 2017: Proceedings of the SIGCHI Conference on Human Factors in Computing Systems
https://www.readbyqxmd.com/read/28514964/help-problems-in-executing-a-pragmatic-randomized-stepped-wedge-trial-on-the-hospital-elder-life-program-to-prevent-delirium-in-older-patients
#9
Noor Heim, Henk F van Stel, Roelof G Ettema, Roos C van der Mast, Sharon K Inouye, Marieke J Schuurmans
BACKGROUND: A pragmatic, stepped wedge trial design can be an appealing design to evaluate complex interventions in real-life settings. However, there are certain pitfalls that need to be considered. This paper reports on the experiences and lessons learned from the conduct of a cluster randomized, stepped wedge trial evaluating the effect of the Hospital Elder Life Program (HELP) in a Dutch hospital setting to prevent older patients from developing delirium. METHODS: We evaluated our trial which was conducted in eight departments in two hospitals in hospitalized patients aged 70 years or older who were at risk for delirium by reflecting on the assumptions that we had and on what we intended to accomplish when we started, as compared to what we actually realized in the different phases of our study...
May 17, 2017: Trials
https://www.readbyqxmd.com/read/28514792/autonomic-dysregulation-in-burnout-and-depression-evidence-for-the-central-role-of-exhaustion
#10
Magdalena K Kanthak, Tobias Stalder, LaBarron K Hill, Julian F Thayer, Marlene Penz, Clemens Kirschbaum
Objectives Given the important role of the autonomic nervous system (ANS) in stress regulation, astonishingly little is known about ANS functioning in burnout, a condition arising after prolonged exposure to work-related stress. The current study sought to investigate ANS modulation, as indexed by vagally-mediated heart rate variability (HRV), in relation to burnout symptomatology to (i) distinguish associations between the three dimensions of burnout [emotional exhaustion (EE), cynicism, reduced personal accomplishment] and (ii) investigate overlap in associations with depressive symptomatology...
May 18, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28514135/three-dimensional-hetero-integration-of-faceted-gan-on-si-pillars-for-efficient-light-energy-conversion-devices
#11
Dong Rip Kim, Chi Hwan Lee, In Sun Cho, Hanmin Jang, Min Soo Jeon, Xiaolin Zheng
An important pathway for cost-effective light energy conversion devices, such as solar cells and light emitting diodes, is to integrate III-V (e.g., GaN) materials on Si substrates. Such integration first necessitates growth of high crystalline III-V materials on Si, which has been the focus of many studies. However, the integration also requires that the final III-V/Si structure has a high light energy conversion efficiency. To accomplish those twin goals, we use single-crystalline micro-sized Si pillars as a seed layer to first grow faceted Si structures, which are then used for the hetero-epitaxial growth of faceted GaN films...
May 17, 2017: ACS Nano
https://www.readbyqxmd.com/read/28512478/subcutaneous-reaction-of-rat-tissues-to-nanosilver-coated-gutta-percha
#12
Mohammad Ali Mozayeni, Omid Dianat, Shahin Tahvildari, Maryam Mozayani, Payam Paymanpour
INTRODUCTION: Gutta-percha (GP), is a neutral and non-toxic material. The aim of this animal study was to compare the biocompatibility of nanosilver coated GP (NS-GP) with conventional GP in subcutaneous tissues in a rat model. METHODS AND MATERIALS: Conventional GP and NS-GP were subcutaneously implanted in the backs of 20 male Wistar rats (n=10). A control animal was assigned for each trial period. Ten animals were sacrificed after 7 and 30 days and light microscopic evaluation of tissue reaction to NS-GP (n=20) and conventional GP (n=20) was accomplished...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28511925/total-correction-of-tetralogy-of-fallot-at-early-age-a-study-of-183-cases
#13
Mohamed Alassal, Bedir M Ibrahim, Hany M Elrakhawy, Magdy Hassenien, Sameh Sayed, Magdy Elshazly, Nabil Elsadeck
BACKGROUND: Opinions regarding the optimal time for the repair of tetralogy of Fallot vary. A debate also exists about the timing of repair for the asymptomatic infant. METHODS: This study included 183 patients with tetralogy of Fallot. All patients were subjected to clinical examination with measurement of oxygen saturation, 12-lead ECG, plain chest x-ray, and complete laboratory investigation. Echocardiography and cardiac catheterisation were indicated if there was an inability to reach diagnosis by echocardiography, suspicion of coronary anomaly, evaluation of distal pulmonary arteries or suspicion of major aorto-pulmonary collaterals...
April 27, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28511803/group-members-questions-shape-participation-in-health-counselling-and-health-education
#14
Aija Logren, Johanna Ruusuvuori, Jaana Laitinen
OBJECTIVE: This study examines how group members' questions shape member participation in health counselling and health education groups. METHODS: The study applies conversation analytic principles as a method. The data consist of video-recorded health education lessons in secondary school and health counselling sessions for adults with a high risk of Type 2 diabetes. RESULTS: Group members' questions accomplish a temporary change in participatory roles...
May 6, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28511321/-impact-of-cyp2c19-genotype-and-platelet-function-on-clinical-outcome-in-coronary-atherosclerotic-heart-diseases-patients-received-clopidogrel-post-percutaneous-coronary-intervention
#15
Y Wu, X X Zhang, L Tian, J J Jiang, L Xu, Y L Huang, H Liu, Y S Li
Objective: To analyze association of CYP2C19 genotype and platelet function phenotype and their impact on clinical outcomes including bleeding events of coronary artery disease(CAD) patients received clopidogrel post percutaneous coronary intervention(PCI). Methods: Coronary atherosclerotic heart diseases patients underwent elective PCI and coronary stent implantation in Fuwai hospital were prospectively enrolled during May 2012 to April 2013. Patients were assigned into groups by genotype of CYP2C19 (extensive metabolizers, intermediate metabolizers, and poor metabolizers) and phenotype of platelet function (clopidogrel responders, semi-responders, and non-responders)...
May 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28510257/strategy-for-selection-of-soybean-genotypes-tolerant-to-drought-during-germination
#16
S A G Dantas, F C S Silva, L J Silva, F L Silva
Water deficit is the main reason for instability in the context of soybean culture. The development of strategies for the selection of more tolerant genotypes is necessary. These strategies include the use of polyethylene glycol 6000 solutions (PEG-6000) for conducting the germination test under conditions of water restriction. Thus, the objective of this study was to determine the osmotic potential and the main characteristics that promote the discrimination of soybean genotypes with regard to water stress tolerance during germination and the vigor test...
May 10, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28509333/altered-glycan-accessibility-on-native-immunoglobulin-g-complexes-in-early-rheumatoid-arthritis-and-its-changes-during-therapy
#17
Judith Stümer, Mona H C Biermann, Jasmin Knopf, Iryna Magorivska, Alf Kastbom, Anna Svärd, Christina Janko, Rostyslav Bilyy, Georg Schett, Christopher Sjöwall, Martin Herrmann, Luis E Muñoz
The goal of this study was to investigate the glycosylation profile of native IgG present in serum immune complexes in patients with rheumatoid arthritis (RA). To accomplish this, lectin binding assays, detecting the accessibility of glycans present on IgG-containing immune complexes by biotinylated lectins were employed. Lectins capturing fucosyl residues (AAL), fucosylated tri-mannose N-glycan core sites (LCA), terminal sialic acid residues (SNA) and O-glycosidically-linked galactose/N-acetylgalactosamine (GalNac-L) were used...
May 16, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/28507800/formyl-peptide-receptor-1-suppresses-gastric-cancer-angiogenesis-and-growth-by-exploiting-inflammation-resolution-pathways
#18
Nella Prevete, Federica Liotti, Anna Illiano, Angela Amoresano, Piero Pucci, Amato de Paulis, Rosa Marina Melillo
Chronic inflammation can result from inadequate engagement of resolution mechanisms, mainly accomplished by specialized pro-resolving mediators (SPMs) arising from the metabolic activity of lipoxygenases (ALOX5/15) on ω-6 or ω-3 essential polyunsaturated fatty acids (PUFA). We previously demonstrated that formyl peptide receptor 1 (FPR1) suppresses gastric cancer (GC) by inhibiting its inflammatory/angiogenic potential. In this study, we asked whether FPR1 exploits inflammation resolution pathways to suppress GC angiogenesis and growth...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28507695/ani-1-an-extensible-neural-network-potential-with-dft-accuracy-at-force-field-computational-cost
#19
J S Smith, O Isayev, A E Roitberg
Deep learning is revolutionizing many areas of science and technology, especially image, text, and speech recognition. In this paper, we demonstrate how a deep neural network (NN) trained on quantum mechanical (QM) DFT calculations can learn an accurate and transferable potential for organic molecules. We introduce ANAKIN-ME (Accurate NeurAl networK engINe for Molecular Energies) or ANI for short. ANI is a new method designed with the intent of developing transferable neural network potentials that utilize a highly-modified version of the Behler and Parrinello symmetry functions to build single-atom atomic environment vectors (AEV) as a molecular representation...
April 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28507686/gas-confinement-in-compartmentalized-coordination-polymers-for-highly-selective-sorption
#20
Mónica Giménez-Marqués, Néstor Calvo Galve, Miguel Palomino, Susana Valencia, Fernando Rey, Germán Sastre, Iñigo J Vitórica-Yrezábal, Mónica Jiménez-Ruiz, J Alberto Rodríguez-Velamazán, Miguel A González, José L Jordá, Eugenio Coronado, Guillermo Mínguez Espallargas
Discrimination between different gases is an essential aspect for industrial and environmental applications involving sensing and separation. Several classes of porous materials have been used in this context, including zeolites and more recently MOFs. However, to reach high selectivities for the separation of gas mixtures is a challenging task that often requires the understanding of the specific interactions established between the porous framework and the gases. Here we propose an approach to obtain an enhanced selectivity based on the use of compartmentalized coordination polymers, named CCP-1 and CCP-2, which are crystalline materials comprising isolated discrete cavities...
April 1, 2017: Chemical Science
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