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https://www.readbyqxmd.com/read/28619289/validation-of-a-method-for-dose-of-the-day-calculation-in-head-neck-tomotherapy-by-using-planning-ct-to-mvct-deformable-image-registration
#1
M Branchini, C Fiorino, I Dell'Oca, M L Belli, L Perna, N Di Muzio, R Calandrino, S Broggi
PURPOSE: The aim of this study was to test the feasibility and dosimetric accuracy of a method that employs planning CT-to-MVCT deformable image registration (DIR) for calculation of the daily dose for head and neck (HN) patients treated with Helical Tomotherapy (HT). METHODS: For each patient, the planning kVCT (CTplan) was deformably registered to the MVCT acquired at the 15th therapy session (MV15) with a B-Spline Free Form algorithm using Mattes mutual information (open-source software 3D Slicer), resulting in a deformed CT (CTdef)...
June 12, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28610691/radiological-properties-of-3d-printed-materials-in-kilovoltage-and-megavoltage-photon-beams
#2
O L Dancewicz, S R Sylvander, T S Markwell, S B Crowe, J V Trapp
PURPOSE: This study evaluates the radiological properties of different 3D printing materials for a range of photon energies, including kV and MV CT imaging and MV radiotherapy beams. METHODS: The CT values of a number of materials were measured on an Aquilion One CT scanner at 80kVp, 120kVp and a Tomotherapy Hi Art MVCT imaging beam. Attenuation of the materials in a 6MV radiotherapy beam was investigated. RESULTS: Plastic filaments printed with various infill densities have CT values of -743±4, -580±1 and -113±3 in 120kVp CT images which approximate the CT values of low-density lung, high-density lung and soft tissue respectively...
June 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28610690/investigating-output-and-energy-variations-and-their-relationship-to-delivery-qa-results-using-statistical-process-control-for-helical-tomotherapy
#3
Diana Binny, Emilio Mezzenga, Craig M Lancaster, Jamie V Trapp, Tanya Kairn, Scott B Crowe
The aims of this study were to investigate machine beam parameters using the TomoTherapy quality assurance (TQA) tool, establish a correlation to patient delivery quality assurance results and to evaluate the relationship between energy variations detected using different TQA modules. TQA daily measurement results from two treatment machines for periods of up to 4years were acquired. Analyses of beam quality, helical and static output variations were made. Variations from planned dose were also analysed using Statistical Process Control (SPC) technique and their relationship to output trends were studied...
June 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28580762/static-beam-tomotherapy-as-an-optimisation-method-in-whole-breast-radiation-therapy-wbrt
#4
Matthew Squires, Yunfei Hu, Mikel Byrne, Ben Archibald-Heeren, Sonja Cheers, Bruno Bosco, Amy Teh, Andrew Fong
INTRODUCTION: TomoTherapy (Accuray, Sunnyvale, CA) has recently introduced a static form of tomotherapy: TomoDirect™ (TD). This study aimed to evaluate TD against a contemporary intensity modulated radiation therapy (IMRT) alternative through comparison of target and organ at risk (OAR) doses in breast cancer cases. A secondary objective was to evaluate planning efficiency by measuring optimisation times. METHODS: Treatment plans of 27 whole-breast radiation therapy (WBRT) patients optimised with a tangential hybrid IMRT technique were replanned using TD...
June 4, 2017: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/28555505/comparison-of-dose-distribution-for-head-and-neck-cancer-patients-with-and-without-dose-painting-escalation-during-radiotherapy-realized-with-tomotherapy-unit
#5
Malgorzata Skorska, Tomasz Piotrowski, Adam Ryczkowski
OBJECTIVES: To determine and quantify the percentage dose increase to organs at risk (OARs) with multiple level dose painting (DP) for patients with head and neck cancer in comparison with standard regimen. METHODS: Twelve patients who had undergone 18F-FDG-PET/CT ([18-F]fluoro-2-deoxy-D-glucose positron emission tomography [18F-FDG-PET]) scan were retrospectively enrolled. Two treatment plans-one using DP escalation and one without-were optimized for each patient base on PET/CT data...
May 30, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28535917/sensitivity-evaluation-of-two-commercial-dosimeters-in-detecting-helical-tomotherapy-treatment-delivery-errors
#6
Shrikant Deshpande, Mark Geurts, Philip Vial, Peter Metcalfe, Lois Holloway
PURPOSE: To assess the sensitivity of two commercial dosimetry systems in detecting Helical TomoTherapy (HT) delivery errors. METHOD: Two commercial dosimeters i) MatriXX(Evolution) and ii) ArcCHECK® were considered. Ten retrospective nasopharynx HT patients were analysed. For each patient, error plans were created by independently introducing systematic offsets in: a) Jaw width error ±1, ±1.5 and ±2mm, b) Couch speed error ±2%, ±2.5, ±3% and ±4%, and c) MLC Leaf Open Time (MLCLOT) errors (3 separate MLC errors: either leaf 32 open or leaf 42 remains open during delivery, and 4% random reductions in MLCLOT)...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28532617/first-french-experiences-of-total-body-irradiations-using-helical-tomotherapy-%C3%A2
#7
R Sun, X Cuenca, R Itti, S Nguyen Quoc, J-P Vernant, J-J Mazeron, C Jenny, M Chea
PURPOSE: Dynamic conformal radiotherapy with helical TomoTherapy(®) (HT) offers a more quantitative paradigm for total body irradiation. Treatment planning, delivery, dose verification of the first French experiences of total body irradiation using helical TomoTherapy(®) are presented. MATERIALS AND METHODS: Patients planned for total body irradiation at our institution from February 2012 to May 2013 were reported. Total body irradiation consisted in a single fraction of 2Gy...
May 19, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28526192/comparison-of-spinal-stereotactic-body-radiotherapy-sbrt-planning-techniques-intensity-modulated-radiation-therapy-modulated-arc-therapy-and-helical-tomotherapy
#8
Jina Kim, Hong Seok Jang, Yeon Sil Kim, Byung Ock Choi, Young-Nam Kang
Stereotactic body radiotherapy (SBRT) delivers a highly conformal, hypofractionated radiation dose to a small target with minimal radiation applied to the surrounding areas. Therefore, using the proper treatment planning techniques for SBRT is important. Intensity modulation techniques, such as static intensity-modulated radiation therapy (IMRT), modulated arc therapy (mARC), and helical tomotherapy (HT), are useful for spinal SBRT because of a rapid dose fall-off and spinal cord avoidance. This study compared the planning characteristics for hypofractionated spinal SBRT administered using 3 treatment techniques...
May 16, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28508830/dosimetric-verification-of-dose-calculation-algorithm-in-the-lung-during-total-marrow-irradiation-using-helical-tomotherapy
#9
Ewelina Konstanty, Julian Malicki, Katarzyna Łagodowska, Anna Kowalik
INTRODUCTION: Treatment of proliferative diseases of the hematopoietic system involves, in most cases, chemotherapy combined with radiation therapy, which is intended to provide adequate immunosuppressant. Conventionally, total body irradiation (TBI) was used; however, total marrow irradiation (TMI) performed with helical tomotherapy (HT) has been proposed as an alternative, with the aim of delivering the highest dose in the target area (skeleton bone). PURPOSE: The purpose of this study is to evaluate the accuracy of the dose calculation algorithm for the lung in TMI delivered with HT...
January 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28499662/-acute-toxicity-of-breast-cancer-irradiation-with-modulated-intensity-by-tomotherapy-%C3%A2
#10
N Aoulad, C Massabeau, B de Lafontan, L Vieillevigne, G Hangard, C Ciprian, L Chaltiel, É Moyal, F Izar
PURPOSE: Helical radiation intensity modulated by tomotherapy improves dose distribution to complex and large volumes. The aim of the study was to assess acute toxicity of this technique during breast cancer irradiation after conserving surgery or mastectomy. PATIENTS AND METHODS: Cutaneous toxicities, lung and oesophageal side effects, and breast lymphedema were retrospectively collected according to the Common Terminology Criteria for Adverse Events Version 4...
May 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28478891/-epithelioid-hemangioendothelioma-of-the-spine-a-case-report
#11
O Munier, B Muckensturm, M Fesneau, T Wachter
Epithelioid hemangioendothelioma is a rare vascular tumour, with features between hemangiomas and angiosarcomas. Evolution remains mainly local but may also metastasize. Here, we report a case of a patient with a spinal epithelioid hemangioendothelioma. After a first resection, local recurrence required a new excision and external radiotherapy. It was achieved by helical TomoTherapy(®) with intensity modulation. During the follow-up, a second inoperable spinal location necessitated a new sequence of radiotherapy in modulation of intensity with integrated boost...
May 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28466155/dosimetric-implications-of-inter-and-intrafractional-prostate-positioning-errors-during-tomotherapy-comparison-of-gold-marker-based-registrations-with-native-mvct
#12
Peter Wust, Marc Joswig, Reinhold Graf, Dirk Böhmer, Marcus Beck, Thomasz Barelkowski, Volker Budach, Pirus Ghadjar
INTRODUCTION: For high-dose radiation therapy (RT) of prostate cancer, image-guided (IGRT) and intensity-modulated RT (IMRT) approaches are standard. Less is known regarding comparisons of different IGRT techniques and the resulting residual errors, as well as regarding their influences on dose distributions. PATIENTS AND METHODS: A total of 58 patients who received tomotherapy-based RT up to 84 Gy for high-risk prostate cancer underwent IGRT based either on daily megavoltage CT (MVCT) alone (n = 43) or the additional use of gold markers (n = 15) under routine conditions...
May 2, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28464517/long-term-dosimetric-stability-of-multiple-tomotherapy-delivery-systems
#13
Jennifer B Smilowitz, David Dunkerley, Patrick M Hill, Poonam Yadav, Mark W Geurts
The dosimetric stability of six TomoTherapy units was analyzed to investigate changes in performance over time and with system upgrades. Energy and output were tracked using monitor chamber signal, onboard megavoltage computed tomography (MVCT) detector profile, and external ion chamber measurements. The systems (and monitoring periods) include three Hi-Art (67, 61, and 65 mos.), two TomoHDA (31 and 26 mos.), and one Radixact unit (11 mos.), representing approximately 10 years of clinical use. The four newest systems use the Dose Control Stability (DCS) system and Fixed Target Linear Accelerator (linac) (FTL)...
May 2, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28449713/dosimetric-comparison-of-helical-tomotherapy-vmat-fixed-field-imrt-and-3d-conformal-radiotherapy-for-stage-i-ii-nasal-natural-killer-t-cell-lymphoma
#14
Xianfeng Liu, Erliang Huang, Ying Wang, Yanan He, Huanli Luo, Mingsong Zhong, Da Qiu, Chao Li, Han Yang, Guanglei He, Juan Zhou, Fu Jin
BACKGROUND: The aim of this study was to compare radiotherapy plans for Stage I-II nasal natural killer/T-cell lymphoma (NNKTL) using helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), Fixed-Field intensity-modulated radiotherapy (IMRT), and three-dimensional conformal radiotherapy (3D-CRT). METHODS: Eight patents with Stage I-II NNKTL treated with IMRT were re-planned for HT, VMAT (two full arcs), and 3D-CRT. The quality of target coverage, the exposure of normal tissue and the efficiency of radiation delivery were analyzed...
April 27, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28444831/analysis-of-modulation-factor-to-shorten-the-delivery-time-in-helical-tomotherapy
#15
Hidetoshi Shimizu, Koji Sasaki, Hiroyuki Tachibana, Natsuo Tomita, Chiyoko Makita, Kuniyasu Nakashima, Kazushi Yokoi, Takashi Kubota, Manabu Yoshimoto, Tohru Iwata, Takeshi Kodaira
A low modulation factor (MF) maintaining a good dose distribution contributes to the shortening of the delivery time and efficiency of the treatment plan in helical tomotherapy. The purpose of this study was to reduce the delivery time using initial values and the upper limit values of MF. First, patients with head and neck cancer (293 cases) or prostate cancer (181 cases) treated between June 2011 and July 2015 were included in the analysis of MF values. The initial MF value (MFinitial ) was defined as the average MFactual value, and the upper limit of the MF value (MFUL ) was defined according the following equation: MFUL = 2 × standard deviation of MFactual value + the average MFactual Next, a treatment plan was designed for patients with head and neck cancer (62 cases) and prostate cancer (13 cases) treated between December 2015 and June 2016...
April 26, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28435647/helical-tomotherapy%C3%A2-is-a-safe-and-feasible-technique-for-total-scalp-irradiation
#16
Francesco Cuccia, Vanessa Figlia, Antonella Palmeri, Francesco Verderame, Antonio Lo Casto, Mariella Mannino, Giuseppe Ferrera
Angiosarcoma of the scalp is a rare aggressive tumor that affects elderly patients. Chemoradiation is the treatment of choice for multicentric and extensive disease. The shape of the scalp represents a dosimetric challenge in terms of achieving a homogeneous concave dose distribution with coverage of the entire target volume and an acceptable organs-at-risk sparing. We report a case of an 81-year-old man with a multifocal angiosarcoma of the scalp treated with Helical TomoTherapy® (Accuray Inc., Sunnyvale, CA, USA) intensity modulated radiotherapy...
March 24, 2017: Rare Tumors
https://www.readbyqxmd.com/read/28412923/fdg-pet-ct-predicts-outcome-in-oropharingeal-carcinoma-patients-undergoing-intensity-modulated-radiation-therapy-with-dose-escalation-to-fdg-avid-tumour-volumes
#17
Paola Mapelli, Sara Broggi, Elena Incerti, Pierpaolo Alongi, Margarita Kirienko, Claudio Fiorino, Italo Dell Oca, Federico Fallanca, Emilia Giovanna Vanoli, Nadia Gisella Di Muzio, Luigi Gianolli, Maria Picchio
PURPOSE: To evaluate the predictive value of FDG-PET/CT parameters on outcome of oropharyngeal squamocellular cancer (OSCC) patients undergoing helical tomotherapy (HTT), with dose escalation to FDG-PET/CT positive tumour volumes using the simultaneous integrated boost (SIB) technique. MATERIALS AND METHODS: We analysed 41 patients studied by FDG-PET/CT and treated with radical intent between 2005 and 2014 for OSCC. HTT-SIB was delivered in 30 fractions concomitantly: 69 Gy, as SIB, to the PET-positive volume (biological target volume - BTV-PET), both to the primary tumour (T) and lymph nodes (N), 66 Gy to the T and positive N, 54 Gy to the laterocervical nodes at risk...
April 13, 2017: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/28410684/knowledge-based-treatment-planning-an-inter-technique-and-inter-system-feasibility-study-for-prostate-cancer
#18
Elisabetta Cagni, Andrea Botti, Renato Micera, Maria Galeandro, Roberto Sghedoni, Matteo Orlandi, Cinzia Iotti, Luca Cozzi, Mauro Iori
PURPOSE: Helical Tomotherapy (HT) plans were used to create two RapidPlan knowledge-based (KB) models to generate plans with different techniques and to guide the optimization in a different treatment planning system for prostate plans. Feasibility and performance of these models were evaluated. MATERIAL AND METHODS: two sets of 35 low risk (LR) and 30 intermediate risk (IR) prostate cancer cases who underwent HT treatments were selected to train RapidPlan models...
April 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28398210/out-of-field-doses-from-pediatric-craniospinal-irradiations-using-3d-crt-imrt-helical-tomotherapy-and-electron-based-therapy
#19
Marijke De Saint-Hubert, Dirk Verellen, Kenneth Poels, Wouter Crijns, Federica Magliona, Tom Depuydt, Filip Vanhavere, Lara Struelens
Medulloblastoma treatment involves irradiation of the entire central nervous system, i.e. craniospinal irradiation (CSI). This is associated with the significant exposure of large volumes of healthy tissue and there is growing concern regarding treatment-associated side effects. The current study compares out-of-field organ doses in children receiving CSI through 3D-conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT), helical tomotherapy (HT) and an electron-based technique, and includes radiation doses resulting from imaging performed during treatment...
July 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28357632/radiotherapy-for-adrenal-gland-metastases-from-hepatocellular-carcinoma
#20
B-Y Yuan, Y Hu, L Zhang, Y-H Chen, Y-Y Dong, Z-C Zeng
BACKGROUND: Several studies have found benefits of radiotherapy for adrenal metastasis from hepatocellular carcinoma (HCC). However, the efficacy, safety and outcome issues have not yet been fully addressed. Therefore, we performed this study to further elucidate the feasibility and outcome of radiotherapy in treating adrenal metastasis from HCC. METHODS: We retrospectively analyzed 81 patients with adrenal metastasis from HCC between 2001 and 2015. Eighteen patients received helical tomotherapy and 63 patients received conventional radiotherapy, including two-dimensional (2-D) or three-dimensional conformal radiotherapy (3-D CRT)...
March 29, 2017: Clinical & Translational Oncology
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