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Uterine bleeding

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https://www.readbyqxmd.com/read/28924270/clinical-efficacy-of-levonorgestrel-and-norethisterone-for-the-treatment-of-chronic-abnormal-uterine-bleeding
#1
Muhammad Nadeem Ashraf, Agha Habib-Ur-Rehman, Zahid Shehzad, Shakir DakheelAllah AlSharari, Ghulam Murtaza
OBJECTIVE: To compare the clinical efficacy of levonorgestrel intrauterine system with oral norethisterone for the treatment of idiopathic chronic abnormal uterine bleeding. METHODS: This cross-sectional study was conducted at Bahawal Victoria Hospital, Jubilee Female Hospital, Civil Hospital and private clinics of consultant gynaecologists in Bahawalpur, Pakistan, from March to August 2014, and comprised patients presenting with abnormal uterine bleeding. The patients were equally and randomly divided into two groups, i...
September 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28913119/hysteroscopy-a-necessary-method-for-detecting-uterine-pathologies-in-post-menopausal-women-with-abnormal-uterine-bleeding-or-increased-endometrial-thickness
#2
Fatemeh Sarvi, Ashraf Alleyassin, Marzieh Aghahosseini, Marzieh Ghasemi, Sima Gity
OBJECTIVE: To investigate the histologic and hysteroscopic findings of post-menopausal women with uterine bleeding and asymptomatic women with increased endometrial thickness equal or more than 5 mm. MATERIALS AND METHODS: This cross-sectional study was performed between May 2014 and June 2015 on 110 post-menopausal women aged 40-82 years. The women were divided into two groups: Women with abnormal uterine bleeding (AUB group) and asymptomatic women with increased endometrial thickness (asymptomatic group)...
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28911934/evaluation-of-the-efficacy-and-safety-of-dienogest-in-the-treatment-of-painful-symptoms-in-patients-with-adenomyosis-a-randomized-double-blind-multicenter-placebo-controlled-study
#3
Yutaka Osuga, Haruka Fujimoto-Okabe, Atsushi Hagino
OBJECTIVE: To evaluate the efficacy and safety of dienogest (DNG), a progestational 19-norsteroid, in patients with symptomatic adenomyosis. DESIGN: Phase III, randomized, double-blind, multicenter, placebo-controlled study. SETTING: Clinical study sites in Japan. PATIENT(S): Sixty-seven patients with adenomyosis. INTERVENTION(S): Patients were randomly assigned to receive DNG (2 mg/d, orally) or placebo for 16 weeks...
September 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28910998/abnormal-uterine-bleeding
#4
Ying Cheong, Iain T Cameron, Hilary O D Critchley
Introduction: It is not uncommon for a woman to suffer from abnormal uterine bleeding (AUB) or heavy menstrual bleeding (HMB) at some point during her lifetime. Once pathology is excluded, in practice, management needs to be individualised, taking into account the improvement of the woman's symptoms and quality of life. Sources of data: Peer-reviewed journals, governmental and professional society publications. Areas of agreement: There is now agreement on a structured, universal approach to the diagnosis of AUB, with the aide memoirs PALM (polyps, adenomyosis, leiomyoma, malignancy) and COEIN (coagulopathies, ovulatory dysfunction, endometrial, iatrogenic, not otherwise classified)...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28893656/hysteroscopic-isthmoplasty-step-by-step-technique
#5
Attilio Di Spiezio Sardo, Brunella Zizolfi, Gloria Calagna, Pierluigi Giampaolino, Filomena Paolella, Giuseppe Bifulco
BACKGROUND: Isthmocele is a characteristic semi-diverticular anomaly of the anterior isthmic wall of the uterus, located at the site of a previous cesarean delivery scar. The etiopathogenesis of isthmocele is still poorly understood, and several hypotheses have been proposed. Possible factors that could play a role in niche development include a very low incision through cervical tissue, an inadequate suturing technique during the closure of the uterine scar surgical interventions that increase adhesion formation or patient-related factors that impair wound healing, or increase inflammation or adhesion formation...
September 8, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28892298/impact-of-hysteroscopic-surgery-for-isthmocele-associated-with-cesarean-scar-syndrome
#6
Shunichiro Tsuji, Fuminori Kimura, Akiyoshi Yamanaka, Tetsuro Hanada, Kimiko Hirata, Akie Takebayashi, Akiko Takashima, Ayumi Seko-Nitta, Takashi Murakami
AIM: Cesarean scar syndrome (CSS) is characterized by increased risk of postmenstrual abnormal uterine bleeding, dysmenorrhea, and infertility, due to a post-cesarean scar defect known as an isthmocele. This study aimed to assess the impact of hysteroscopic surgery on isthmocele associated with CSS. METHODS: Eighteen patients with CSS were enrolled. Surgical methods included resection of the inferior edge and superficial cauterization of the isthmocele via hysteroscopic surgery...
September 11, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28881800/menstrual-pattern-after-abdominal-radical-trachelectomy
#7
Xiaoqi Li, Jin Li, Xingzhu Ju, Zhaoxia Jiang, Xiaojun Chen, Xiaohua Wu
To assess changes of menstrual patterns, their causes, preventions and treatment methods after abdominal radical trachelectomy (ART), we recorded patients' menstrual patterns after surgery and compared them with the conditions before surgery. Patients were divided into 3 groups based on their menstrual status post-trachelectomy:Group 1: menstrual patterns unchanged; Group 2: menstrual patterns changed without amenorrhea; and Group 3: amenorrhea. One hundred and twenty-nine patients were included: 39 (30.2%) women belonged to Group 1, 74 (57...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28867888/efficacy-of-combined-cabergoline-and-metformin-compared-to-metformin-alone-on-cycle-regularity-in-patients-with-polycystic-ovarian-disease-with-hyperprolactinemia-a-randomized-clinical-trial
#8
Mervat Ali Mohamed Elsersy
PURPOSE: Polycystic ovarian syndrome (PCOS) is a common reproductive disorder. Increasing serum prolactin in these patients could be detected in both follicular and luteal phase of the normal and stimulated cycles. Hyperprolactinemia affects the hypothalamic-pituitary-ovarian axis causing anovulation and abnormal uterine bleeding. In this study, the efficacy of combined cabergoline and metformin therapy was compared to metformin therapy alone in patients with PCOS on the body mass index, androgen profile and menstrual cycle regulation...
October 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28866121/focus-on-uterine-fibroids-evolving-options-to-optimize-care
#9
Sukhbir Sony Singh, Erica E Marsh
No abstract text is available yet for this article.
September 1, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28864269/uses-of-chitosan-for-treating-different-forms-of-serious-obstetrics-hemorrhages
#10
G Carles, C Dabiri, A Mchirgui, E O Saoudi, N Hcini, K Pouget, B Seve, B de Matteis
Postpartum hemorrhage is a major cause of maternal death worldwide. Many therapeutic strategies have been developed to reduce maternal morbidity and mortality like oxytocin, prostaglandin, and uterine balloons. A new member of the therapeutic arsenal has recently emerged, the chitosan (Celox(®)), used since several years by military doctors to stop bleeding of combat wounds. In 2012, a first study was reported with the successful use of chitosan-coated gauze to treat severe postpartum hemorrhage. We report here four cases of the use of chitosan to treat life-threatening obstetric bleeding...
August 31, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28858685/laparoscopy-during-pregnancy-case-report-and-key-points-to-improve-laparoscopic-management
#11
REVIEW
Josep Estadella, Pia Español, Beatriz Grandal, Marta Gine, Juan Parra
A 34-year-old woman in her 19th week of gestation was admitted to the Emergency Department of our hospital for acute abdominal pain. The patient was diagnosed with haemoperitoneum. Laparoscopy was performed and revealed acute bleeding from a crumbly superficial uterine vascular network. Haemostasis was achieved and both mother and foetus recovered well after surgery. A caesarean section was performed at 38 weeks, delivering a healthy newborn and revealing that the pregnancy had developed in a rudimentary hemiuterus...
August 18, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28856861/high-intensity-focused-ultrasound-combined-with-hysteroscopic-resection-for-the-treatment-of-placenta-accreta
#12
M Ye, Z Yin, M Xue, X Deng
OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of a combination of high-intensity focused ultrasound (HIFU) and hysteroscopic resection while treating placenta accreta (PA). DESIGN: A retrospective study. SETTING: A university teaching hospital in China. METHODS: This study included 25 patients diagnosed with PA who underwent HIFU followed by hysteroscopic resection in our hospital between January 2014 and December 2015...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28856666/fly-thru-imaging-feasibility-study-and-comparison-with-outpatient-hysteroscopy
#13
Sumathi Rajendran, Ritu Mogra, Ying Li, Bradley de Vries, Jon Hyett
BACKGROUND: In the investigation of abnormal uterine bleeding, hysteroscopy with endometrial biopsy is considered the gold standard. Fly Thru™ imaging is a new application used to generate virtual hysteroscopy clips. AIMS: We aimed to investigate the feasibility and diagnostic accuracy of sonohysterogram with virtual hysteroscopy as an alternative to outpatient diagnostic hysteroscopy. MATERIALS AND METHODS: Two separate cohorts of women were recruited...
August 30, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28852646/the-role-of-hysteroscopy-in-the-diagnosis-and-treatment-of-adenomyosis
#14
REVIEW
Attilio Di Spiezio Sardo, Gloria Calagna, Fabrizia Santangelo, Brunella Zizolfi, Vasilis Tanos, Antonino Perino, Rudy Leon De Wilde
Uterine adenomyosis is a common gynecologic disorder in women of reproductive age, characterized by the presence of ectopic endometrial glands and stroma within the myometrium. Dysmenorrhea, abnormal uterine bleeding, chronic pelvic pain, and deep dyspareunia are common symptoms of this pathological condition. However, adenomyosis is often an incidental finding in specimens obtained from hysterectomy or uterine biopsies. The recent evolution of diagnostic imaging techniques, such as transvaginal sonography, hysterosalpingography, and magnetic resonance imaging, has contributed to improving accuracy in the identification of this pathology...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28852453/myomectomies-for-massive-hemoperitoneum-from-spontaneous-bleeding-of-a-uterine-myoma
#15
I Kassegne, K Kolani, B Tchangai, K Kanassoua, K Adabra, F Alassani, A K Amavi, E D J Dosseh
Massive hemoperitoneum from spontaneous bleeding of uterine myoma is an extremely rare condition, that needs urgent surgical exploration. We report a 40-year-old woman, admitted for acute onset of abdominal pain. Physical examination revealed hypovolemic shock. The hemoglobin level was of 5 g/dL. Ultrasonography revealed hemoperitoneum. Emergency surgical exploration was planned. There was hemoperitoneum of 3 L, uterine myomas with multiple subserous myomas, bleeding from superficial ruptured varice overlying the most largest subserous myoma, which measured 15 cm...
July 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28851349/the-utilization-of-traditional-chinese-medicine-in-patients-with-dysfunctional-uterine-bleeding-in-taiwan-a-nationwide-population-based-study
#16
Yi-Rong Lin, Mei-Yao Wu, Jen-Huai Chiang, Hung-Rong Yen, Su-Tso Yang
BACKGROUND: Many patients with gynecological disorders seek traditional medicine consultations in Asian countries. This study intended to investigate the utilization of traditional Chinese medicine (TCM) in patients with dysfunctional uterine bleeding (DUB) in Taiwan. METHODS: We analyzed a cohort of one million individuals randomly selected from the National Health Insurance Research Database in Taiwan. We included 46,337 subjects with newly diagnosed DUB (ICD-9-CM codes 626...
August 29, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28843713/postablation-neuroma-of-the-myometrium-a-report-of-5-cases
#17
Stewart F Cramer, Debra S Heller
When hysterectomy is performed for chronic pelvic pain, routine pathology examination often provides no explanation. However, analysis of small uterine nerves using immunostains may help to address this deficiency. Small uterine nerves tend to be sparse or absent in wide areas of normal myometrium. Some studies of uterine nerves have suggested that endometriosis, adenomyosis, and fibroids are not inherently painful, with increased small nerves in the inner uterine wall associated with the history of pelvic pain...
August 23, 2017: Human Pathology
https://www.readbyqxmd.com/read/28836862/impact-of-uterine-fibroid-symptoms-on-health-related-quality-of-life-of-us-women-evidence-from-a-cross-sectional-survey
#18
Ahmed M Soliman, Mary Kay Margolis, Jane Castelli-Haley, Mahesh J Fuldeore, Charlotte D Owens, Karin S Coyne
BACKGROUND: Uterine fibroids (UF) are associated with significant health-related quality of life (HRQL) impact. This study examined the impact of UF symptoms on HRQL. METHODS: An online cross-sectional survey of 18 to 49 year US women was conducted and collected demographics, UF prevalence, symptoms, and HRQL using the UFS-QOL. Descriptive statistics were used to examine the impact of symptom presence, severity, bothersomeness, and number of UF symptoms on HRQL...
August 24, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28834996/uterine-extramedullary-plasmacytoma-as-a-primary-manifestation-of-multiple-myeloma
#19
Ana Codorniz, Renato Cunha, Fernando Fernandes, Maria João Pais, Tiago Neves, Carlos Quintana
The association between plasmacytomas and multiple myeloma (MM) is well-described, and in about one third of the cases of plasmacytoma the additional study will lead to the diagnosis of MM. The finding of plasmacytomas in the genital tract is extremely rare, with sparse cases described in the literature, and these cases pose a challenge regarding the optimal guidance and treatment. This paper describes a case of uterine extramedullary plasmacytoma in a 79-year-old woman with complaints of postmenopausal abnormal uterine bleeding...
September 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28833082/use-of-bulldog-vascular-clamps-to-reduce-intraoperative-bleeding-during-cesarean-hysterectomy-for-placenta-percreta
#20
Polat Dursun
Postpartum hemorrhage causes 25% of all maternal deaths worldwide and is the leading cause of maternal morbidity and mortality following vaginal or caesarean delivery. Every year, postpartum hemorrhage is estimated to cause approximately 125 000 maternal deaths and is associated with morbidity among 20 million women. It is caused by several obstetric conditions, including uterine atony and placental problems such as placenta accreta spectrum disorders, trauma, and lacerations. Several techniques are known to prevent postpartum hemorrhage, including uterine cavity tamponade, uterine artery ligation, uterine artery embolization, pre-cesarean prophylactic balloon catheterization, uterine compression sutures, hypogastric artery ligation, and hysterectomy...
August 21, 2017: International Journal of Gynaecology and Obstetrics
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