keyword
https://read.qxmd.com/read/38655430/age-related-changes-in-static-balance-in-older-women-aged-in-their-early-sixties-to-their-late-eighties-different-aging-patterns-in-the-anterior-posterior-and-mediolateral-directions
#1
JOURNAL ARTICLE
Shun Sasagawa, Ai Arakawa, Aimi Furuyama, Yasuo Matsumoto
OBJECTIVE: The aim of this study was to cross-sectionally investigate how static balance changes throughout the aging process in older women aged from their early sixties to their late eighties. METHODS: Forty-six older women (aged 62-89 years) were requested to stand barefoot and quietly on a force platform for 30 s with their eyes either open or closed. During the trials, the position of the center of foot pressure (CoP) and the acceleration of the body's center of mass (ACC) were measured...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38654376/a-comprehensive-multivariate-analysis-of-the-center-of-pressure-during-quiet-standing-in-patients-with-parkinson-s-disease
#2
JOURNAL ARTICLE
Shintaro Fujii, Yusaku Takamura, Koki Ikuno, Shu Morioka, Noritaka Kawashima
BACKGROUND: We hypothesized that postural instability observed in individuals with Parkinson's disease (PD) can be classified as distinct subtypes based on comprehensive analyses of various evaluated parameters obtained from time-series of center of pressure (CoP) data during quiet standing. The aim of this study was to characterize the postural control patterns in PD patients by performing an exploratory factor analysis and subsequent cluster analysis using CoP time-series data during quiet standing...
April 23, 2024: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/38651457/spontaneous-oscillation-of-an-active-filament-under-viscosity-gradients
#3
JOURNAL ARTICLE
Zhaorong Liu, Youchuang Chao, Zhijun Zheng, Lailai Zhu
We investigate the effects of uniform viscosity gradients on the spontaneous oscillations of an elastic, active filament in viscous fluids. Combining numerical simulations and linear stability analysis, we demonstrate that a viscosity gradient increasing from the filament's base to tip destabilises the system, facilitating its self-oscillation. This effect is elucidated through a reduced-order model, highlighting the delicate balance between destabilising active forces and stabilising viscous forces. Additionally, we reveal that while a perpendicular viscosity gradient to the filament's orientation minimally affects instability, it induces asymmetric ciliary beating, thus generating a net flow along the gradient...
April 23, 2024: Soft Matter
https://read.qxmd.com/read/38649020/drafting-behaviors-in-fish-induced-by-a-local-pressure-drop-around-a-hydrofoil-model
#4
JOURNAL ARTICLE
Go Eguchi, Tsutomu Takagi, Shinsuke Torisawa, Kohsei Takehara
Fish schooling has the improvement in hydrodynamic propulsive efficiency through the interaction of flow field induced by fish bodies and tail beat. Such energy-saving behaviors due to flow interactions also occur with changes in the flow field caused by structures. We examined the differences between a live fish swimming around a streamlined hydrofoil model prepared to represent fish body and swimming alone in a flow tank. We observed that the fish can remain in the same place without tail beating. It called "drafting" behavior...
April 20, 2024: Journal of Theoretical Biology
https://read.qxmd.com/read/38645161/sox9-marks-limbal-stem-cells-and-is-required-for-asymmetric-cell-fate-switch-in-the-corneal-epithelium
#5
Gabriella Rice, Olivia Farrelly, Sixia Huang, Paola Kuri, Ezra Curtis, Lisa Ohman, Ning Li, Christopher Lengner, Vivian Lee, Panteleimon Rompolas
Adult tissues with high cellular turnover require a balance between stem cell renewal and differentiation, yet the mechanisms underlying this equilibrium are unclear. The cornea exhibits a polarized lateral flow of progenitors from the peripheral stem cell niche to the center; attributed to differences in cellular fate. To identify genes that are critical for regulating the asymmetric fates of limbal stem cells and their transient amplified progeny in the central cornea, we utilized an in vivo cell cycle reporter to isolate proliferating basal cells across the anterior ocular surface epithelium and perform single-cell transcriptional analysis...
April 11, 2024: bioRxiv
https://read.qxmd.com/read/38643231/relationship-between-the-strength-of-the-ankle-and-toe-muscles-and-functional-stability-in-young-healthy-adults
#6
JOURNAL ARTICLE
Kajetan J Słomka, Justyna Michalska
This study investigates the relationship between ankle and toe strength and functional stability in young adults, with a sample comprising sixteen females and fourteen males. The research employed force platform data to determine the center of foot pressure (COP) and calculated the forward functional stability index (FFSI) through foot anthropometric measurements. Strength measurements of toe and ankle muscles, during maximal isometric flexion and extension, were conducted using force transducers. Notable positive correlations were found between toe flexor strength and FFSI (left flexor: r = 0...
April 21, 2024: Scientific Reports
https://read.qxmd.com/read/38640839/to-what-extent-can-mastication-functionality-be-restored-following-mandibular-reconstruction-surgery-a-computer-modeling-approach
#7
JOURNAL ARTICLE
Hamidreza Aftabi, Benedikt Sagl, John E Lloyd, Eitan Prisman, Antony Hodgson, Sidney Fels
STATEMENT OF PROBLEM: Advanced cases of head and neck cancer involving the mandible often require surgical removal of diseased sections and subsequent replacement with donor bone. During the procedure, the surgeon must make decisions regarding which bones or tissues to resect. This requires balancing tradeoffs related to issues such as surgical access and post-operative function; however, the latter is often difficult to predict, especially given that long-term functionality also depends on the impact of post-operative rehabilitation programs...
April 17, 2024: Computer Methods and Programs in Biomedicine
https://read.qxmd.com/read/38639679/consensus-statements-on-the-current-landscape-of-artificial-intelligence-applications-in-endoscopy-addressing-roadblocks-and-advancing-artificial-intelligence-in-gastroenterology
#8
Sravanthi Parasa, Tyler Berzin, Cadman Leggett, Seth Gross, Alessandro Repici, Omer F Ahmad, Austin Chiang, Nayantara Coelho-Prabhu, Jonathan Cohen, Evelien Dekker, Rajesh N Keswani, Charles E Kahn, Cesare Hassan, Nicholas Petrick, Peter Mountney, Jonathan Ng, Michael Riegler, Yuichi Mori, Yutaka Saito, Shyam Thakkar, Irving Waxman, Michael Bradley Wallace, Prateek Sharma
BACKGROUND AND AIMS: The American Society for Gastrointestinal Endoscopy (ASGE) AI Task Force along with experts in endoscopy, technology space, regulatory authorities, and other medical subspecialties initiated a consensus process that analyzed the current literature, highlighted potential areas, and outlined the necessary research in artificial intelligence (AI) to allow a clearer understanding of AI as it pertains to endoscopy currently. METHODS: A modified Delphi process was used to develop these consensus statements...
April 16, 2024: Gastrointestinal Endoscopy
https://read.qxmd.com/read/38639642/managing-expectations-and-imbalanced-training-data-in-reactive-force-field-development-an-application-to-water-adsorption-on-alumina
#9
JOURNAL ARTICLE
Loïc Dumortier, Céline Chizallet, Benoit Creton, Theodorus de Bruin, Toon Verstraelen
ReaxFF is a computationally efficient model for reactive molecular dynamics simulations that has been applied to a wide variety of chemical systems. When ReaxFF parameters are not yet available for a chemistry of interest, they must be (re)optimized, for which one defines a set of training data that the new ReaxFF parameters should reproduce. ReaxFF training sets typically contain diverse properties with different units, some of which are more abundant (by orders of magnitude) than others. To find the best parameters, one conventionally minimizes a weighted sum of squared errors over all of the data in the training set...
April 19, 2024: Journal of Chemical Theory and Computation
https://read.qxmd.com/read/38635355/constructing-a-novel-moderately-modulus-rigid-flexible-structure-with-synergistic-reinforcement-on-the-carbon-fiber-surface-to-enhance-the-mechanical-properties-of-carbon-fiber-epoxy-composites-at-elevated-temperatures
#10
JOURNAL ARTICLE
Peifeng Feng, Lichun Ma, Mingguang Zhang, Yiling Quan, Mingzhuan Li, Xin Zhou, Xingyao Liu, Xigao Jian, Jian Xu
To improve the mechanical performance of carbon fiber (CF)/epoxy composites in high-temperature environments, a moderately modulus gradient modulus interlayer was constructed at the interface phase region of composites. This involved the design of a "rigid-flexible" synergistic reinforcement structure, incorporating rigid nanoparticle GO@CNTs and a flexible polymer polynaphthyl ether nitrile ketone onto the CF surface. Notably, at 180 °C, compared to commercial CF composites, the CF-GO@CNTs-PPENK composites displayed a remarkable improvement in their mechanical characteristics (interfacial shear, interlaminar shear, flexural strength, and modulus), achieving enhancements of 173...
April 18, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38633000/interplay-of-halogen-bonding-and-solvation-in-protein-ligand-binding
#11
JOURNAL ARTICLE
Maria Luisa Verteramo, Majda Misini Ignjatović, Rohit Kumar, Sven Wernersson, Vilhelm Ekberg, Johan Wallerstein, Göran Carlström, Veronika Chadimová, Hakon Leffler, Fredrik Zetterberg, Derek T Logan, Ulf Ryde, Mikael Akke, Ulf J Nilsson
Halogen bonding is increasingly utilized in efforts to achieve high affinity and selectivity of molecules designed to bind proteins, making it paramount to understand the relationship between structure, dynamics, and thermodynamic driving forces. We present a detailed analysis addressing this problem using a series of protein-ligand complexes involving single halogen substitutions - F, Cl, Br, and I - and nearly identical structures. Isothermal titration calorimetry reveals an increasingly favorable binding enthalpy from F to I that correlates with the halogen size and σ-hole electropositive character, but is partially counteracted by unfavorable entropy, which is constant from F to Cl and Br, but worse for I...
April 19, 2024: IScience
https://read.qxmd.com/read/38632784/correlations-in-a-weakly-interacting-two-dimensional-random-flow
#12
JOURNAL ARTICLE
I V Kolokolov, V V Lebedev, V M Parfenyev
We analytically examine fluctuations of vorticity excited by an external random force in two-dimensional fluid. We develop the perturbation theory enabling one to calculate nonlinear corrections to correlation functions of the flow fluctuations found in the linear approximation. We calculate the correction to the pair correlation function and the triple correlation function. It enables us to establish the criterion of validity of the perturbation theory for different ratios of viscosity and bottom friction...
March 2024: Physical Review. E
https://read.qxmd.com/read/38630747/perinatal-mortality-in-german-dairy-cattle-unveiling-the-importance-of-cow-level-risk-factors-and-their-interactions-using-a-multifaceted-modelling-approach
#13
JOURNAL ARTICLE
Yury Zablotski, Katja Voigt, Martina Hoedemaker, Kerstin E Müller, Laura Kellermann, Heidi Arndt, Maria Volkmann, Linda Dachrodt, Annegret Stock
Perinatal mortality (PM) is a common issue on dairy farms, leading to calf losses and increased farming costs. The current knowledge about PM in dairy cattle is, however, limited and previous studies lack comparability. The topic has also primarily been studied in Holstein-Friesian cows and closely related breeds, while other dairy breeds have been largely ignored. Different data collection techniques, definitions of PM, studied variables and statistical approaches further limit the comparability and interpretation of previous studies...
2024: PloS One
https://read.qxmd.com/read/38629542/-spatial-temporal-evolution-and-quantitative-attribution-of-habitat-quality-in-typical-karst-counties-of-guizhou-plateau
#14
JOURNAL ARTICLE
Yue Li, Xia Feng, Lu-Hua Wu, Guang-Jie Luo, Hong-Fen Luo
The purpose of this study was to reveal the spatial and temporal evolution patterns of habitat quality in karst counties of Guizhou plateau and its driving factors and to provide scientific basis for balanced ecological conservation and sustainable development of karst regions. Using DEM data, meteorological data, socio-economic data, and four periods of land use data in 1989, 2003, 2010, and 2020, the InVEST model was used to analyze the spatial and temporal evolution characteristics of habitat quality in Puding County from 1989 to 2020 and to quantitatively detect the driving forces of its spatial divergence...
May 8, 2024: Huan Jing Ke Xue= Huanjing Kexue
https://read.qxmd.com/read/38629052/the-effect-of-electromyographic-feedback-functional-electrical-stimulation-on-the-plantar-pressure-in-stroke-patients-with-foot-drop
#15
JOURNAL ARTICLE
Xiaoting Li, Hanting Li, Yu Liu, Weidi Liang, Lixin Zhang, Fenghua Zhou, Zhiqiang Zhang, Xiangnan Yuan
PURPOSE: The purpose of this study was to observe, using Footscan analysis, the effect of electromyographic feedback functional electrical stimulation (FES) on the changes in the plantar pressure of drop foot patients. METHODS: This case-control study enrolled 34 stroke patients with foot drop. There were 17 cases received FES for 20 min per day, 5 days per week for 4 weeks (the FES group) and the other 17 cases only received basic rehabilitations (the control group)...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38628701/a-bibliometric-analysis-of-cerebral-palsy-from-2003-to-2022
#16
Yue Hu, Yadan Zheng, Yue Yang, Wenfeng Fang, Maomao Huang, Dan Li, Zhangyu Xu, Fangyuan Xu, Jianxiong Wang
PURPOSE: This bibliometric study explores cerebral palsy (CP) research from 2003 to 2022 to reveal the topic hotspots and collaborations. METHODS: We retrieved studies on CP from the Web of Science Core Collection from 2003 to 2022 and then used CiteSpace and Bibliometrix to perform a bibliometric analysis and attain knowledge mapping, including publication outputs, funding, journals, authors, institutions, countries/territories, keywords, collaborative relationships, and topic hotspots...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38628647/relationships-between-trace-elements-and-cognitive-and-depressive-behaviors-in-sprague-dawley-and-wistar-albino-rats
#17
JOURNAL ARTICLE
Melis Yavuz, Ekin Dongel Dayanc, Fatma Merve Antmen, Elif Keskinöz, Esra Altuntaş, Gökçen Dolu, Berkcan Koç, Emre Tunçcan, Damla Şakar, Ufuk Canözer, Ceyda Büyüker, Ece Polat, Metincan Erkaya, Rui Azevedo, Devrim Öz Arslan, Agostinho Almeida, Güldal Süyen
Introduction: This study investigates the effects of social isolation on mental health and cognitive functions in Sprague Dawley (SD) and Wistar Albino (WIS) rat strains, prompted by the heightened awareness of such impacts amid the COVID-19 pandemic. This study aims to explore the impact of social isolation on memory, learning, and behavioral changes in middle-aged SD and WIS rat strains and to investigate cortical trace element levels, seeking potential correlations between these levels and the observed behavioral responses to social isolation...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38628368/a-novel-semi-dominant-mutation-in-brassinosteroid-signaling-kinase1-increases-stomatal-density
#18
JOURNAL ARTICLE
Eigo Ando, Kyomi Taki, Takamasa Suzuki, Toshinori Kinoshita
Stomata play a pivotal role in balancing CO2 uptake for photosynthesis and water loss via transpiration. Thus, appropriate regulation of stomatal movement and its formation are crucial for plant growth and survival. Red and blue light induce phosphorylation of the C-terminal residue of the plasma membrane (PM) H+ -ATPase, threonine, in guard cells, generating the driving force for stomatal opening. While significant progress has been made in understanding the regulatory mechanism of PM H+ -ATPase in guard cells, the regulatory components for the phosphorylation of PM H+ -ATPase have not been fully elucidated...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/38625839/the-effects-of-plantarflexor-weakness-and-reduced-tendon-stiffness-with-aging-on-gait-stability
#19
JOURNAL ARTICLE
Ross E Smith, Andrew D Shelton, Gregory S Sawicki, Jason R Franz
Falls among older adults are a costly public health concern. Such falls can be precipitated by balance disturbances, after which a recovery strategy requiring rapid, high force outputs is necessary. Sarcopenia among older adults likely diminishes their ability to produce the forces necessary to arrest gait instability. Age-related changes to tendon stiffness may also delay muscle stretch and afferent feedback and decrease force transmission, worsening fall outcomes. However, the association between muscle strength, tendon stiffness, and gait instability is not well established...
2024: PloS One
https://read.qxmd.com/read/38623312/postural-balance-in-copd-with-obstructive-sleep-apnoea-a-cross-sectional-study
#20
JOURNAL ARTICLE
Caroline Maschio de Censo, Viviane Vieira Passini, Bárbara Aparecida Teodoro Alcantara Verri, Rafaella Fagundes Xavier, Regina Maria Carvalho-Pinto, Geraldo Lorenzi-Filho, Celso R F Carvalho
OBJECTIVE: The aim of this study was to assess the postural balance in COPD patients with obstructive sleep apnoea (OSA). Physical activity, anxiety and depression symptoms, mood, and falls were also assessed in this population. METHODS: Moderate to severe COPD patients were assessed for laboratory and clinical postural balance (force platform and mini-balance evaluation systems test (Mini-BESTest)), physical activity (accelerometry), OSA (polysomnography), sleep quality (Pittsburgh Sleep Quality Index), sleepiness (Epworth Sleepiness Scale), anxiety and depression symptoms (Hospital Anxiety and Depression Scale), dyspnoea (modified Medical Research Council), clinical status (COPD Assessment Test) and mood (Brunel Mood Scale)...
March 2024: ERJ Open Research
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