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Kyle I S Harrington, Curtis T Rueden, Kevin W Eliceiri
Summary: FunImageJ is a Lisp framework for scientific image processing built upon the ImageJ software ecosystem. The framework provides a natural functional-style for programming, while accounting for the performance requirements necessary in big data processing commonly encountered in biological image analysis. Availability and implementation: Freely available plugin to Fiji ( Installation and use instructions available at http://imagej...
March 1, 2018: Bioinformatics
Warren A Hunt, Matt Kaufmann, J Strother Moore, Anna Slobodova
The ACL2 theorem prover has seen sustained industrial use since the mid-1990s. Companies that have used ACL2 regularly include AMD, Centaur Technology, IBM, Intel, Kestrel Institute, Motorola/Freescale, Oracle and Rockwell Collins. This paper introduces ACL2 and focuses on how and why ACL2 is used in industry. ACL2 is well-suited to its industrial application to numerous software and hardware systems, because it is an integrated programming/proof environment supporting a subset of the ANSI standard Common Lisp programming language...
October 13, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
Bohdan B Khomtchouk, Edmund Weitz, Peter D Karp, Claes Wahlestedt
No abstract text is available yet for this article.
September 1, 2017: Briefings in Bioinformatics
Kai Wang, Zhan Zhang, Chang Liu, Qiang Fu, Wenzhan Xu, Chongwen Huang, R A Weiss, Xiong Gong
In this paper, we report the highly efficient bulk heterojunction (BHJ) polymer solar cells (PSCs) with an inverted device structure via utilizing an ultrathin layer of lithium sulfonated polystyrene (LiSPS) ionomer to reengineer the surface of the solution-processed zinc oxide (ZnO) electron extraction layer (EEL). The unique lithium-ionic conductive LiSPS contributes to enhanced electrical conductivity of the ZnO/LiSPS EEL, which not only facilitates charge extraction from the BHJ active layer but also minimizes the energy loss within the charge transport processes...
February 6, 2017: ACS Applied Materials & Interfaces
Bohdan B Khomtchouk, Edmund Weitz, Peter D Karp, Claes Wahlestedt
We present a rationale for expanding the presence of the Lisp family of programming languages in bioinformatics and computational biology research. Put simply, Lisp-family languages enable programmers to more quickly write programs that run faster than in other languages. Languages such as Common Lisp, Scheme and Clojure facilitate the creation of powerful and flexible software that is required for complex and rapidly evolving domains like biology. We will point out several important key features that distinguish languages of the Lisp family from other programming languages, and we will explain how these features can aid researchers in becoming more productive and creating better code...
May 1, 2018: Briefings in Bioinformatics
Priscila M A Denapoli, Bianca F Zanetti, Adara A Dos Santos, Jane Z de Moraes, Sang W Han
Carcinoembryonic antigen (CEA) is expressed during embryonic life and in low level during adult life. Consequently, the CEA is recognized by the immune system as a self-antigen and thus CEA-expressing tumors are tolerated. Previously, we constructed a single chain variable fragment using the 6.C4 (scFv6.C4) hybridoma cell line, which gave rise to antibodies able to recognize CEA when C57/Bl6 mice were immunized. Here, the scFv6.C4 ability to prevent the CEA-expressing tumor growth was assessed in CEA-expressing transgenic mice CEA2682...
March 2017: Cancer Immunology, Immunotherapy: CII
E Portegijs, S Sipilä, A Viljanen, M Rantakokko, T Rantanen
The aim is to determine concurrent validity of a single self-report habitual physical activity (PA) question against accelerometer-based PA and mobility variables, and corresponding changes in self-reported PA and mobility. Cross-sectional and longitudinal data of the "Life-space mobility in old age" (LISPE) cohort and its substudy on PA were utilized. At baseline, 848 community-dwelling, 75- to 90-year-old people living independently in central Finland participated in home-based interviews. One and 2 years later, 816 and 761 of them were reassessed by phone, respectively...
November 2017: Scandinavian Journal of Medicine & Science in Sports
Dong Zhang, Ying-Qiang Ge, Xin-Yu Li, Xian-Hui Liu, Ming Zhang, Rong-Rong Wang
Species of Lispe caesia-group from Palaearctic and adjacent regions are reviewed. Diagnostic characters of this group are updated. One new synonymy is established: L. frontalis Zielke, 1972, syn. nov. for L. leucocephala Loew, 1856. Key to males of ten species (with two subspecies) from Palaearctic, Oriental and Ethiopian regions is given. Nine species (with two subspecies) are photographed. Six species and one subspecies are redescribed. More detailed ultrastructural or external characters for male swollen hind tarsi and the wing interference patterns are also provided...
April 5, 2016: Zootaxa
Li-Tang Tsai, Merja Rantakokko, Taina Rantanen, Anne Viljanen, Markku Kauppinen, Erja Portegijs
BACKGROUND: Our aim was to study the relationship between objectively measured physical activity and subsequent changes in life-space mobility over 2 years among older people. Life-space mobility refers to the area a person moves through in daily life, taking into account frequency, and need of assistance. Life-space mobility and physical activity correlate, but whether different intensities of objectively assessed physical activity predicts decline in life-space mobility is not known...
November 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Colin Webster
Hippocratic authors frequently utilise silence, babbling, lisping and otherverbal signs to diagnose a variety of physical illnesses and predict theircourse. This chapter examines these 'voice pathologies' and evaluatestheir impact on the dialogue between patients and Hippocratic physicians. In short, Hippocratic authors treat patients' voices in two dissonant ways. On the one hand, physicians promote some form of discourse,implicitly relying on patients to report internal sensations resulting fromillnesses...
2016: Studies in Ancient Medicine
K Grob, M Manestar, A Lang, T Ackland, H Gilbey, M S Kuster
INTRODUCTION: With a subvastus approach to the femur, the vessels that perforate the lateral intermuscular septum (LISP-vessels) must be ligated. The effect on the blood supply to the femur remains unclear. The purpose of the current study was to investigate the effect of ligation of the LISP-Vessels on the blood supply and to examine the anatomy of the LISP-vessels and the anastomoses around the femur. MATERIALS: In six human cadavers the LISP vessels were ligated by a lateral subvastus approach on one side...
December 2015: Injury
Milla Saajanaho, Merja Rantakokko, Erja Portegijs, Timo Törmäkangas, Johanna Eronen, Li-Tang Tsai, Marja Jylhä, Taina Rantanen
OBJECTIVE: Life-space mobility - the spatial extent of mobility in daily life - is associated with quality of life and physical functioning but may also be influenced by future orientation expressed in personal goals. The aim of this study was to explore how different personal goals predict changes in older people's life-space mobility. METHODS: This prospective cohort study with a 2-year follow-up included 824 community-dwelling people aged 75 to 90 years from the municipalities of Jyväskylä and Muurame in Central Finland...
December 2015: Preventive Medicine
L-T Tsai, E Portegijs, M Rantakokko, A Viljanen, M Saajanaho, J Eronen, T Rantanen
The purpose of this cross-sectional study was to investigate the association between objectively measured physical activity and life-space mobility in community-dwelling older people. Life-space refers to the spatial area a person purposefully moves through in daily life (bedroom, home, yard, neighborhood, town, and beyond) and life-space mobility to the frequency of travel and the help needed when moving through different life-space areas. The study population comprised community-living 75- to 90-year-old people {n = 174; median age 79...
August 2015: Scandinavian Journal of Medicine & Science in Sports
Nguyen Van De, Vu Thi Nga, Pierre Dorny, Nguyen Vu Trung, Pham Ngoc Minh, Do Trung Dung, Edoardo Pozio
Trichinellosis is a zoonotic parasitic disease with a worldwide distribution. The aim of this work was to describe the epidemiological and clinical data of five outbreaks of trichinellosis, which affected ethnic minorities living in remote mountainous areas of northwestern Vietnam from 1970 to 2012. Trichinellosis was diagnosed in 126 patients, of which 11 (8.7%) were hospitalized and 8 (6.3%) died. All infected people had consumed raw pork from backyard and roaming pigs or wild boar at wedding, funeral, or New Year parties...
June 2015: American Journal of Tropical Medicine and Hygiene
Dan Hua Xu, Min Yuan, Jian Wen Wang, Yun Zhen Hu
Osmotic demyelination syndrome (ODS) may be precipitated by aggressive correction of a hypoosmolar state. We report the case of a 24-year-old woman who developed ODS during rapid correction of asymptomatic hyponatremia caused by pituitrin prescribed for hemoptysis. After hyponatremia correction by NaCl supplementation, the patient developed limb weakness, blurred vision, hand and perioral numbness, and lisp. Magnetic resonance imaging (MRI) revealed bilateral signal hyperintensity of the globus pallidus and caudate nucleus, compatible with extra-pontine ODS...
May 2015: International Journal of Clinical Pharmacology and Therapeutics
Matthew Fenwick, Colbert Sesanker, Martin R Schiller, Heidi Jc Ellis, M Lee Hinman, Jay Vyas, Michael R Gryk
Scientists are continually faced with the need to express complex mathematical notions in code. The renaissance of functional languages such as LISP and Haskell is often credited to their ability to implement complex data operations and mathematical constructs in an expressive and natural idiom. The slow adoption of functional computing in the scientific community does not, however, reflect the congeniality of these fields. Unfortunately, the learning curve for adoption of functional programming techniques is steeper than that for more traditional languages in the scientific community, such as Python and Java, and this is partially due to the relative sparseness of available learning resources...
2012: Proceedings of the ... International Conference on Information Technology: New Generations
Catarina Falk Kieri, Birgitta Bergendal, Lisbet K Lind, Marcus Schmitt-Egenolf, Christina Stecksén-Blicks
BACKGROUND: Mutations in the EDAR-gene cause hypohidrotic ectodermal dysplasia, however, the oral phenotype has been described in a limited number of cases. The aim of the present study was to clinically describe individuals with the c.1072C > T mutation (p. Arg358X) in the EDAR gene with respect to dental signs and saliva secretion, symptoms from other ectodermal structures and to assess orofacial function. METHODS: Individuals in three families living in Sweden, where some members had a known c...
2014: BMC Medical Genetics
Merja Rantakokko, Susanne Iwarsson, Satu Vahaluoto, Erja Portegijs, Anne Viljanen, Taina Rantanen
BACKGROUND: We examined the association between perceived environmental barriers to outdoor mobility and loneliness among community-dwelling older people. In addition, we studied whether walking difficulties and autonomy in participation outdoors affected this association. METHODS: Cross-sectional analyses of face-to-face home interview data with 848 people aged 75-90 years (mean age: 80.1 years; 62% women) gathered within the "Life-Space Mobility in Old Age" (LISPE) project...
December 2014: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
F J Trevor Burke
UNLABELLED: Toothwear is affecting increasing numbers of the population. In the past, treatment of patients whose teeth were affected by toothwear often involved the reduction of these teeth for crowns; a severe form of toothwear. Contemporary management of such cases is by the bonding of resin composite restorations to the worn and wearing surfaces, with these restorations being placed at an increased occlusal vertical dimension. The advantage of the technique is its minimal- or non-intervention nature and its high reported degree of patient satisfaction...
January 2014: Dental Update
John Van Borsel, Anneleen Van de Putte
The present study examined the popular stereotype that gay men lisp by evaluating to what extent listeners associated dental or frontal articulation/lisping with gayness. Fifteen heterosexual males and 15 heterosexual females listened to 275 samples of read speech and judged the sexual orientation of the speakers. A total of 175 of the samples were of homosexual men, 74 (42.3 %) of which had been identified with lisping in a previous study; 100 were of heterosexual men, 18 (18 %) of which had been identified with lisping previously...
August 2014: Archives of Sexual Behavior
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