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https://www.readbyqxmd.com/read/28160864/inulin-type-fructan-and-infusion-of-artemisia-vulgaris-protect-the-liver-against-carbon-tetrachloride-induced-liver-injury
#1
Marília Locatelli Corrêa-Ferreira, Maria Helena Verdan, Francislaine Aparecida Dos Reis Lívero, Larissa Favaretto Galuppo, José Ederaldo Queiroz Telles, Maria Élida Alves Stefanello, Alexandra Acco, Carmen Lúcia de Oliveira Petkowicz
BACKGROUND: Infusions of aerial parts of Artemisia vulgaris L. (Asteraceae) are used in herbal medicine to treat several disorders, including hepatosis. PURPOSE: Evaluation of in vivo hepatoprotective effects of A. vulgaris infusion (VI) and inulin (VPI; i.e., the major polysaccharide of VI). STUDY DESIGN: The hepatoprotective effect of A. vulgaris extracts on carbon tetrachloride (CCl4)-induced hepatotoxicity and the probable mechanism involved in this protection were investigated in mice...
January 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28141791/former-very-preterm-infants-show-alterations-in-plasma-amino-acid-profiles-at-a-preschool-age
#2
Anna Posod, Susanne Müller, Irena Odri Komazec, Daniel Dejaco, Ulrike Pupp Peglow, Elke Griesmaier, Sabine Scholl-Bürgi, Daniela Karall, Ursula Kiechl-Kohlendorfer
BACKGROUND: Amino acid analysis is a valuable tool for cardiovascular risk assessment. Preterm infants display plasma amino acid changes in the newborn period. Whether these changes persist is unknown to date. The aim of the present study was to assess whether former very preterm infants (VPI) show alterations in amino acid patterns indicative of an unfavorable cardiovascular risk profile at a preschool age. METHODS: Five- to seven-year-old children born at term or <32 weeks' gestation (VPI) were included in the study...
January 31, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28116979/long-term-incidence-of-velopharyngeal-insufficiency-and-other-sequelae-following-uvulopalatopharyngoplasty
#3
Jessica A Tang, Anna M Salapatas, Lauren B Bonzelaar, Michael Friedman
Objective The aim of this study is to (1) assess incidence of long-term velopharyngeal insufficiency (VPI) and (2) determine other sequelae following classic and modified uvulopalatopharyngoplasty (UPPP and mUPPP) for treatment of obstructive sleep apnea (OSA). Data Sources Medline, PubMed, Cochrane Library database. Review Methods A systematic review was performed following standard Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Original research articles reporting on sequelae of UPPP and mUPPP for treatment of OSA, at a mean of 1 year follow-up, were included...
January 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28112331/-detection-of-parainfluenza-virus-in-immunocompromised-and-immunocompetent-patients-in-a-tertiary-hospital-in-sao-paulo-brazil
#4
Sheila N Parmezan, Clarice Camargo, Aripuanã Watanabe, Patricio Godoy-Martínez, Celso Granato, Nancy Bellei
Parainfluenza virus infections (PIV) were evaluated in patients with mild and severe infections through real time PCR. One thousand and sixty-seven samples were collected from subjects as follows: 233 adult renal transplanted outpatients, 129 children with congenital heart disease, 381 with adult hematopoietic stem cell patients and 324 hospitalized patients suspected of influenza A (H1N1) pdm09 infection. PIV was detected in 74 (6.9%) samples. VPI-3 was the most frequent (60.8%) and a higher risk was observed for older adults (p = 0...
October 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28088400/hospitalizations-for-respiratory-syncytial-virus-and-vaccine-preventable-infections-in-the-first-2-years-after-pediatric-liver-transplant
#5
Amy G Feldman, Shikha S Sundaram, Brenda L Beaty, Allison Kempe
OBJECTIVES: To examine in liver transplant recipients at centers participating in the Pediatric Health Information System dataset the number of hospitalizations for respiratory syncytial virus (RSV) and vaccine-preventable infections (VPIs) in the first 2 years after transplantation, morbidity and mortality associated with these hospitalizations, and costs associated with these hospitalizations. STUDY DESIGN: A retrospective cohort study of patients <18 years of age who underwent liver transplantation at a Pediatric Health Information System center between January 1, 2004, and December 31, 2012...
January 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28033190/modified-superior-based-pharyngeal-flap-is-effective-in-treatment-of-velopharyngeal-insufficiency-regardless-of-the-preoperative-closure-pattern
#6
Omer Ekin, Mert Calis, Mavis Emel Kulak Kayikci, Mehtap Icen, Riza Onder Gunaydin, Figen Ozgur
Velopharyngeal insufficiency (VPI) is certainly one of the most important problems confronted after cleft palate repairs. In this study, it was aimed to evaluate the preoperative and postoperative speaking results of patients who underwent modified superior-based pharyngeal flap. Sixty-six children who underwent modified superiorly based pharyngeal flap for treatment of VPI between 2005 and 2013 were retrospectively reviewed. The study population was evaluated in 2 distinctive groups depending on their preoperative velopharyngeal closure pattern as: coronal closure pattern or noncoronal closure patterns (ie, circular, sagittal with or without the presence of a Passavant ridge)...
December 28, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28025442/clinical-efficacy-of-a-1-matricaria-chamomile-l-mouthwash-and-0-12-chlorhexidine-for-gingivitis-control-in-patients-undergoing-orthodontic-treatment-with-fixed-appliances
#7
Paula Goes, Caio S Dutra, Mário R P Lisboa, Delane V Gondim, Renata Leitão, Gerly A C Brito, Rodrigo O Rego
This pilot study evaluated the clinical efficacy of a mouthwash containing 1% Matricaria chamomilla L. (MTC) extract in reducing gingival inflammation and plaque formation in patients undergoing orthodontic treatment with fixed appliances. This randomized, double-blind, placebo-controlled study enrolled a total of 30 males and females (age, 10-40 years) with fixed orthodontic appliances and a minimum of 20 natural teeth. The participants were allocated to three groups (n = 10 each) and asked to rinse with 15 mL of a placebo, 0...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/27999606/traditional-chinese-medicine-qpyf-as-preventive-treatment-for-clostridium-difficile-associated-diarrhea-in-a-mouse-model
#8
Guo Ya-Nan, Wang Jun, Zhang Hao-Jun, Jia Hong-Bing, Li Ping, Liu Xin-Zhu
Traditional Chinese medicine QPYF has a good effect for treating antibiotic-associated diarrhea in clinical practice. The aim of this study is to test its efficacy to prevent Clostridium difficile associated diarrhea (CDAD) in a mouse model. C57BL/6 mice were infected with Clostridium difficile VPI 10463 after exposure to antimicrobial mixture. QPYF was administered from 7 days prior to Clostridium difficile infection to 20 days after infection, and its effect was compared with no treatment and receiving placebo...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27993377/recurrence-pattern-of-pathologic-stage-i-lung-adenocarcinoma-with-visceral-pleural%C3%A2-invasion
#9
Dhihintia Jiwangga, Sukki Cho, Kwhanmien Kim, Sanghoon Jheon
BACKGROUND: Visceral pleural invasion (VPI) is well known to be a poor prognostic factor in lung adenocarcinoma. There were few studies reporting postoperative recurrence pattern in lung adenocarcinoma with VPI. This study was to evaluate the clinical effect of VPI on recurrence pattern in pathologic stage I lung adenocarcinoma after curative resection. METHODS: Among 574 patients with pathologic stage I lung adenocarcinoma after complete resection between 2003 and 2012, the clinicopathologic characteristics of 89 patients (16%) who had recurrence were retrospectively reviewed...
December 16, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27976762/the-total-and-the-differential-mean-pore-anisotropy-in-porous-solids-and-the-ranking-of-pores-according-to-zipf-s-law
#10
Antigoni Margellou, Philippos Pomonis
In this work the property of total pore anisotropy in porous solids is introduced. Its calculation is based on a combination of the specific surface area Sp and the specific pore volume Vp estimated via typical nitrogen porosimetry data and tested in two kinds of porous materials: a group of spinels CoAl2O4 with differentiated random porosities and a second group of silicas SiO2 with ordered porosity modulated by the addition of LaFeO3 nanoparticles. Two basic complementary expressions of total pore anisotropy were estimated: (i) the specific total mean pore anisotropy bmean,total = (N·b) ≈ [Sp(3)]/[Vp(2)] corresponding to the total anisotropy value of all N hypothetical similar pores in one gram of a solid with mean size Dmean = 4Vp/Sp and anisotropy b = Ltotal/Dmean...
January 4, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27939039/velopharyngeal-insufficiency-treated-with-levator-muscle-repositioning-and-unilateral-myomucosal-buccinator-flap
#11
Robrecht J H Logjes, Maaike T A van den Aardweg, Meike M J Blezer, Anne M B van der Heul, Corstiaan C Breugem
PURPOSE: Velopharyngeal insufficiency (VPI) is common (20-30%) after cleft palate closure. The myomucosal buccinator flap has become an important treatment option for velopharyngeal insufficiency; however, published studies all use bilateral buccinator flaps. This study assesses outcomes with a unilateral myomucosal buccinator flap that might result in less operating time and might prevent the need of a bite block and an extra procedure for division of the flap pedicle at a later stage...
January 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27845364/a-genomic-island-in-vibrio-cholerae-with-vpi-1-site-specific-recombination-characteristics-contains-crispr-cas-and-type-vi-secretion-modules
#12
Maurizio Labbate, Fabini D Orata, Nicola K Petty, Nathasha D Jayatilleke, William L King, Paul C Kirchberger, Chris Allen, Gulay Mann, Ankur Mutreja, Nicholas R Thomson, Yan Boucher, Ian G Charles
Cholera is a devastating diarrhoeal disease caused by certain strains of serogroup O1/O139 Vibrio cholerae. Mobile genetic elements such as genomic islands (GIs) have been pivotal in the evolution of O1/O139 V. cholerae. Perhaps the most important GI involved in cholera disease is the V. cholerae pathogenicity island 1 (VPI-1). This GI contains the toxin-coregulated pilus (TCP) gene cluster that is necessary for colonization of the human intestine as well as being the receptor for infection by the cholera-toxin bearing CTX phage...
November 15, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27787538/injection-pharyngoplasty-with-autologous-fat-as-treatment-for-stress-velopharyngeal-insufficiency-in-brass-and-woodwind-musicians
#13
Mausumi N Syamal, Paul C Bryson
Importance: Stress velopharyngeal insufficiency (SVPI) is an uncommon but often career-threatening condition affecting professional brass and woodwind musicians. Objectives: To review the evaluation of and treatment for SVPI in professional musicians with lipoinjection to the posterior pharyngeal wall. Design, Setting, and Participants: A retrospective medical record and literature review. Two professional musicians with SVPI treated with autologous lipoinjection to the posterior pharyngeal wall were included...
February 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27786291/non-toxigenic-environmental-vibrio-cholerae-o1-strain-from-haiti-provides-evidence-of-pre-pandemic-cholera-in-hispaniola
#14
Taj Azarian, Afsar Ali, Judith A Johnson, Mohammad Jubair, Eleonora Cella, Massimo Ciccozzi, David J Nolan, William Farmerie, Mohammad H Rashid, Shrestha Sinha-Ray, Meer T Alam, J Glenn Morris, Marco Salemi
Vibrio cholerae is ubiquitous in aquatic environments, with environmental toxigenic V. cholerae O1 strains serving as a source for recurrent cholera epidemics and pandemic disease. However, a number of questions remain about long-term survival and evolution of V. cholerae strains within these aquatic environmental reservoirs. Through monitoring of the Haitian aquatic environment following the 2010 cholera epidemic, we isolated two novel non-toxigenic (ctxA/B-negative) Vibrio cholerae O1. These two isolates underwent whole-genome sequencing and were investigated through comparative genomics and Bayesian coalescent analysis...
October 27, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27727413/improvement-of-quality-of-speech-in-patients-with-velo-pharyngeal-insufficiency-corrected-using-a-buccinator-myomucosal-flap
#15
D K Dias, P D Fernando, R D Dissanayake
INTRODUCTION: Oro-facial clefts involving the palate is the commonest structural defect causing velopharyngeal insufficiency (VPI) and poor intelli gibility of speech. Proper repair of the soft palateis a surgical challenge. Posterior-based buccinator myomucosal flap (BMF) is used to lengthen the soft palate of patients who undergo primary palatoplasty at Teaching Hospital, Karapitiya (THK). BMF is a good choice for the repair of medium sized mucosal defects in the oral cavity since it has appropriate thickness, contains mucous membrane with mucous glands and has a rich blood supply...
2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/27639596/counterselection-employing-mutated-phes-for-markerless-genetic-deletion-in-bacteroides-species
#16
Yasuhiro Kino, Haruyuki Nakayama-Imaohji, Masashi Fujita, Ayano Tada, Saori Yoneda, Kazuya Murakami, Masahito Hashimoto, Tetsuya Hayashi, Katsuichiro Okazaki, Tomomi Kuwahara
Markerless gene deletion is necessary for multiple gene disruptions due to the limited number of antibiotic resistant markers for some bacteria. However, even in transformable strains, obtaining the expected mutation without a marker requires laborious screening of a large number of colonies. Previous studies had success in various bacteria with a counter-selection system where a conditional lethal gene was incorporated into the vector. We examined the efficacy of the mutated pheS gene (pheS*) as a counter-selective marker for gene deletion in Bacteroides...
December 2016: Anaerobe
https://www.readbyqxmd.com/read/27619042/velopharyngeal-videofluoroscopy-providing-useful-clinical-information-in-the-era-of-reduced-dose-radiation-and-safety
#17
Pablo Antonio Ysunza, David Bloom, Kongkrit Chaiyasate, Matthew Rontal, Rachel VanHulle, Kenneth Shaheen, Donald Gibson
BACKGROUND: The state of the art for correcting velopharyngeal insufficiency (VPI) is a surgical procedure which is customized according to findings on imaging procedures: multiplanar videofluoroscopy (MPVF) and flexible videonasopharyngoscopy (FVNP). Recently, the use of MPVF has been challenged because of the potential risk of using ionizing radiation, especially in children. OBJECTIVE: To study whether using a protocol for performing MPVF can effectively decrease radiation dose in patients with VPI while providing useful information for planning surgical correction of VPI in combination with FVNP...
October 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27585294/augmentation-pharyngoplasty-for-treatment-of-velopharyngeal-insufficiency-in-children-results-with-injectable-dextranomer-and-hyaluronic-acid-copolymer
#18
Shelagh A Cofer, Becky Baas, Edythe Strand, Cara C Cockerill
OBJECTIVES/HYPOTHESIS: To evaluate the effectiveness, durability, and safety of a tissue filler (dextranomer and hyaluronic acid copolymer) when injected submucosally in the nasopharynx to treat velopharyngeal insufficiency (VPI) in pediatric patients. STUDY DESIGN: Retrospective case series. METHODS: Charts were reviewed for all patients treated with injectable filler at a tertiary children's center for VPI from April 2010 through September 2013...
September 1, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27563012/factors-influencing-parent-reports-of-facilitators-and-barriers-to-human-milk-supply-in-neonatal-intensive-care-units
#19
Elisabete Alves, Raquel Magano, Mariana Amorim, Conceição Nogueira, Susana Silva
BACKGROUND: Successful human milk supply in neonatal intensive care units (NICUs) requires the development of family-centered services. OBJECTIVE: This study aimed to assess parent perceptions of factors that help or hinder providing human milk to very preterm infants (VPI) in the NICU according to sociodemographic, reproductive, and obstetric characteristics. METHODS: This cross-sectional quantitative study included 120 mothers and 91 fathers of VPI hospitalized in a level 3 NICU located in the Northern Health Region of Portugal (July 2013-June 2014)...
November 2016: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/27517168/visceral-pleural-invasion-is-a-significant-prognostic-factor-in-patients-with-partly-solid-lung-adenocarcinoma-sized-30%C3%A2-mm-or-smaller
#20
Yangki Seok, Eungbae Lee
Background This study analyzed the impact of visceral pleural invasion (VPI) on the disease-free survival (DFS) of patients with partly solid pulmonary adenocarcinoma sized 30 mm or smaller. Method This is a retrospective study of 147 patients with surgically resected pathologic N0 pulmonary adenocarcinoma that had a partly solid appearance on preoperative computed tomography. All patients presented with tumors of size 30 mm or smaller. The DFS rate was estimated using Kaplan-Meier method. A multivariate analysis for prognostic factors was performed using the Cox proportional hazards regression model...
August 12, 2016: Thoracic and Cardiovascular Surgeon
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