keyword
MENU ▼
Read by QxMD icon Read
search

VPI

keyword
https://www.readbyqxmd.com/read/29617190/bile-acid-oxidation-by-eggerthella-lenta-strains-c592-and-dsm-2243-t
#1
Spencer C Harris, Saravanan Devendran, Celia Méndez-García, Sean M Mythen, Chris L Wright, Christopher J Fields, Alvaro G Hernandez, Isaac Cann, Phillip B Hylemon, Jason M Ridlon
Strains of Eggerthella lenta are capable of oxidation-reduction reactions capable of oxidizing and epimerizing bile acid hydroxyl groups. Several genes encoding these enzymes, known as hydroxysteroid dehydrogenases (HSDH) have yet to be identified. It is also uncertain whether the products of E. lenta bile acid metabolism are further metabolized by other members of the gut microbiota. We characterized a novel human fecal isolate identified as E. lenta strain C592. The complete genome of E. lenta strain C592 was sequenced and comparative genomics with the type strain (DSM 2243) revealed high conservation, but some notable differences...
April 4, 2018: Gut Microbes
https://www.readbyqxmd.com/read/29617152/comparison-of-pre-and-postoperative-sleep-studies-in-patients-undergoing-sphincter-pharyngoplasty
#2
Christina M Busuito, Nathan Vandjelovic, Diana M Flis, Arlene Rozzelle
OBJECTIVE: To determine if sphincter pharyngoplasty changes sleep study parameters on patients undergoing surgery for velopharyngeal insufficiency (VPI). DESIGN: Retrospective chart review on patients undergoing sphincter pharyngoplasty for VPI with pre- and postoperative polysomnography completed. SETTING: Institutional study at a tertiary pediatric hospital. PATIENTS: All patients who underwent sphincter pharyngoplasty over a 20-year period were reviewed; all patients with both pre- and postoperative sleep studies were collected for evaluation...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29605374/primary-augmentation-pharyngoplasty-with-calcium-hydroxylapatite-for-treatment-of-velopharyngeal-insufficiency-surgical-and-speech-outcomes
#3
Patrick D Munson, Alicia Ward
INTRODUCTION: Augmentation pharyngoplasty (AP) is a technique that may effectively treat velopharyngeal insufficiency (VPI), while avoiding typical short and long term surgical risks. This study seeks to determine if children with VPI treated by AP with calcium hydoxylapatite (CaHa) demonstrate clinically significant improvement in speech outcomes. METHODS: Retrospective review (2012-2016) of prospectively collected database of children with VPI, cared for at a single tertiary children's hospital...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29568718/sleep-and-speech-outcomes-after-superior-adenoidectomy-in-children-with-cleft-palate
#4
Emily Waselchuk, James D Sidman, Timothy Lander, Robert Tibesar, Brianne B Roby
Objective To describe the sleep and speech outcomes in patients with cleft palate who underwent superior adenoidectomy. Subjectives and methods This is a case series with chart review of patients with diagnoses of cleft palate and sleep disordered breathing (SDB), obstructive sleep apnea (OSA) or nasal obstruction treated with superior adenoidectomy from 1991-2015 at the Children's Hospital of Minnesota. Postoperative clinic notes documented the changes in symptoms following surgery. All speech outcomes were recorded...
January 21, 2018: Curēus
https://www.readbyqxmd.com/read/29554452/treatment-of-stress-velopharyngeal-incompetence-with-injection-of-hyaluronic-acid
#5
Steven Koprowski, Michael J VanLue, Michael E McCormick
Stress velopharyngeal incompetence (VPI) is a challenging clinical entity that can be managed by a variety of surgical and nonsurgical approaches. We describe the case of a clarinetist who presented with nasal air escape while playing. She had successful improvement in her symptoms after targeted injection of a hyaluronic acid compound to her posterior pharyngeal wall. Our objective is to describe the safety and efficacy of this technique, to emphasize the multidisciplinary management of patients with stress VPI, and to review the importance of both nasopharyngoscopy and videofluoroscopy in their evaluation...
April 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29549366/prognostic-impact-of-the-findings-on-thin-section-computed-tomography-in-stage-i-lung-adenocarcinoma-with-visceral-pleural-invasion
#6
Mei Yuan, Jin-Yuan Liu, Teng Zhang, Yu-Dong Zhang, Hai Li, Tong-Fu Yu
Visceral pleural invasion (VPI) in stageI lung adenocarcinoma is an independent negative prognostic factor. However, no studies proved any morphologic pattern could be referred to as a prognostic factor. Thus, we aim to investigate the potential prognostic impact of VPI by extracting high-dimensional radiomics features on thin-section computed tomography (CT). A total of 327 surgically resected pathological-N0M0 lung adenocarcinoma 3 cm or less in size were evaluated. Radiomics signature was generated by calculating the contribution weight of each feature and validated using repeated leaving-one-out ten-fold cross-validation approach...
March 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29537881/incidence-of-speech-correcting-surgery-in-children-with-isolated-cleft-palate
#7
Charlotta Gustafsson, Arja Heliövaara, Junnu Leikola, Jorma Rautio
OBJECTIVE: Speech-correcting surgeries (pharyngoplasty) are performed to correct velopharyngeal insufficiency (VPI). This study aimed to analyze the need for speech-correcting surgery in children with isolated cleft palate (ICP) and to determine differences among cleft extent, gender, and primary technique used. In addition, we assessed the timing and number of secondary procedures performed and the incidence of operated fistulas. DESIGN: Retrospective medical chart review study from hospital archives and electronic records...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29535205/the-biosynthesis-of-lipooligosaccharide-from-bacteroides-thetaiotaomicron
#8
Amy N Jacobson, Biswa P Choudhury, Michael A Fischbach
Lipopolysaccharide (LPS), a cell-associated glycolipid that makes up the outer leaflet of the outer membrane of Gram-negative bacteria, is a canonical mediator of microbe-host interactions. The most prevalent Gram-negative gut bacterial taxon, Bacteroides , makes up around 50% of the cells in a typical Western gut; these cells harbor ~300 mg of LPS, making it one of the highest-abundance molecules in the intestine. As a starting point for understanding the biological function of Bacteroides LPS, we have identified genes in Bacteroides thetaiotaomicron VPI 5482 involved in the biosynthesis of its lipid A core and glycan, generated mutants that elaborate altered forms of LPS, and used matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry to interrogate the molecular features of these variants...
March 13, 2018: MBio
https://www.readbyqxmd.com/read/29508481/longitudinal-improvement-in-periodontal-parameters-between-rpd-abutment-teeth-with-direct-and-indirect-retainers-after-periodontal-therapy
#9
Mariana Linhares Almeida, Ana Clara Soares de Paiva Tôrres, Kleiton Clécio de Oliveira, Patrícia Dos Santos Calderon, Adriana da Fonte Porto Carreiro, Bruno César de Vasconcelos Gurgel
PURPOSE: To evaluate the effect of basic periodontal treatment on clinical periodontal parameters associated with abutment teeth of patients with mandibular Kennedy class I removable partial dentures (RPD) 18 months after treatment. MATERIALS AND METHODS: Thirty patients with periodontal disease were treated and evaluated according to the following periodontal parameters: visible plaque index (VPI), bleeding on probing (BOP), probing depth (PD), gingival recession (GR), clinical attachment loss (CAL), and keratinized mucosa (KM)...
March 6, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29508458/assessment-of-velopharyngeal-function-with-dual-planar-high-resolution-real-time-spiral-dynamic-mri
#10
Xue Feng, Silvia S Blemker, Josh Inouye, Catherine M Pelland, Li Zhao, Craig H Meyer
PURPOSE: To develop a real-time dynamic MRI method for comprehensive evaluation of velum movement during speech. METHODS: Dynamic MRI has been used to study velopharyngeal insufficiency (VPI) by imaging the movement of the velum during speech, because it can provide good anatomic details with no exposed radiation. To be able to comprehensively evaluate dynamic velum movement, a real-time spiral non-balanced SSFP sequence was developed with simultaneous dual-planar coverage and improved spatial and temporal resolution using a combination of parallel imaging and spatial and temporal compressed sensing to achieve 6 × acceleration...
March 5, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29492535/non-invasive-intracranial-pressure-assessment-in-brain-injured-patients-using-ultrasound-based-methods
#11
Chiara Robba, Danilo Cardim, Tamara Tajsic, Justine Pietersen, Michael Bulman, Frank Rasulo, Rita Bertuetti, Joseph Donnelly, Liu Xiuyun, Zofia Czosnyka, Manuel Cabeleira, Peter Smielewski, Basil Matta, Alessandro Bertuccio, Marek Czosnyka
BACKGROUND: Non-invasive measurement of intracranial pressure (ICP) can be invaluable in the management of critically ill patients. Invasive measurement of ICP remains the "gold standard" and should be performed when clinical indications are met, but it is invasive and brings some risks. In this project, we aim to validate the non-invasive ICP (nICP) assessment models based on arterious and venous transcranial Doppler ultrasonography (TCD) and optic nerve sheath diameter (ONSD)...
2018: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/29490148/double-opposing-z-plasty-for-secondary-surgical-management-of-velopharyngeal-insufficiency-following-primary-furlow-palatoplasty
#12
Arun K Gosain, Harvey Chim, Walter M Sweeney
OBJECTIVE: The present study investigates the efficacy of performing a "palate rerepair" utilizing a double-opposing z-palatoplasty (DOZ) following primary Furlow palatoplasty. DESIGN: Retrospective study. SETTING: Tertiary referral academic center for craniofacial surgery. PATIENTS: 15 consecutive patients who presented with velopharyngeal insufficiency (VPI) after primary Furlow palatoplasty. MAIN OUTCOME MEASURES: All subjects were evaluated using the perceptual speech assessment (PSA) scale...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29473528/novel-genetic-tool-to-study-the-stability-of-genomic-islands
#13
Ashok Kumar, Satyabrata Bag, Bhabatosh Das
BACKGROUND: Genomic islands (GIs) are discrete segments of mobile DNA with defined boundaries, acquired in the bacterial genome from another organism by horizontal gene transfer during the course of evolution. GIs contribute significantly in virulence, disease development, antimicrobial resistance and metabolic process. OBJECTIVE: The present study focuses on the development of a vector based genetic tool carrying selectable and counter-selectable markers, in order to flag the GIs in the bacterial chromosome and monitor their stability in laboratory growth conditions...
February 22, 2018: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/29461876/voice-quality-in-adults-treated-for-unilateral-cleft-lip-and-palate-long-term-follow-up-after-1-or-2-stage-palate-repair
#14
Staffan Morén, Per Åke Lindestad, Mats Holmström, Maria Mani
OBJECTIVES: The aim of the current study was to assess voice quality among adults treated for unilateral cleft lip and palate (UCLP), after 1- or 2-stage palate closure, and compare it to a noncleft control group. STUDY DESIGN: Cross-sectional study in UCLP patients with long-term follow-up and noncleft controls. PARTICIPANTS: UCLP patients born 1960-1987, treated at Uppsala University Hospital, Sweden, were examined (n = 73) at a mean of 35 years after primary surgery...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29437518/safety-and-efficacy-concerns-of-autologous-fat-grafting-for-velopharyngeal-insufficiency
#15
Yun S Phua, Mark J Edmondson, Rachel J Kerr, Kirstie A Macgill, Rodrigo P Teixeira, Jonathan A Burge
OBJECTIVE: Autologous fat grafting of the velopharynx has been well described for the treatment of velopharyngeal insufficiency (VPI), with most studies purporting it as a technique with low morbidity useful in the treatment of mild VPI. Prompted by 3 cases of obstructive sleep apnea (OSA) following fat grafting of the velopharynx, we undertook a review of the outcomes of this procedure at our unit. DESIGN: Retrospective case series. PARTICIPANTS: All patients who underwent autologous fat grafting for VPI at the Royal Children's Hospital Melbourne...
March 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29437510/factors-predicting-hospital-length-of-stay-following-pharyngeal-flap-for-velopharyngeal-insufficiency
#16
Jerry W Chao, Michael J Boyajian, Richard L Amdur, Benjamin J Mitchell, Gary F Rogers, Albert K Oh
OBJECTIVE: Routine hospital admission following pharyngeal flap (PF) to correct velopharyngeal insufficiency (VPI) is the standard at most hospitals. Nevertheless, there is increasing resistance from third-party providers to approve stays longer than a "short stay" (23-hour) observation period. The purpose of the current study was to evaluate length of stay (LOS) and document potential influencing factors following PF. DESIGN: Retrospective chart review...
March 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29437506/speech-and-surgical-outcomes-in-children-with-veau-types-iii-and-iv-cleft-palate-a-comparison-of-internationally-adopted-and-nonadopted-children
#17
Mitchell A Pet, Ryan Dodge, Babette Siebold, Sara Kinter, Jonathan Perkins, Raymond W Tse
OBJECTIVE: This study compares speech and surgical outcomes in internationally adopted and nonadopted patients undergoing cleft palate repair, and examines the influence of age at initial palatoplasty. DESIGN: Retrospective cohort study setting: Tertiary Care Children's Hospital. PATIENTS: 70 international adoptees and 211 nonadoptees with Veau type III and IV clefts (without associated syndrome) repaired at our institution. OUTCOME MEASURES: Outcomes included VPI, compensatory misarticulations, intelligibility, nasal air emission, oronasal fistula, and secondary speech surgery...
March 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29430381/characterization-of-a-glycoside-hydrolase-family-78-%C3%AE-l-rhamnosidase-from-bacteroides-thetaiotaomicron-vpi-5482-and-identification-of-functional-residues
#18
Binchun Li, Yaru Ji, Yanqin Li, Guobin Ding
A putative glycoside hydrolase family 78 α-l-rhamnosidase BtRha78A from Bacteroides thetaiotaomicron VPI-5482 was heterologously over-expressed in Escherichia coli. Enzymatic properties of recombinant BtRha78A were characterized in detail. Recombinant BtRha78A might efficiently hydrolyze p-nitrophenyl α-l-rhamnopyranoside. BtRha78A displayed the highest activity at 60 °C in pH 6.5. BtRha78A exhibited a good pH stability and relatively high thermostability. BtRha78A could be tolerant of a low concentration of alcohols...
February 2018: 3 Biotech
https://www.readbyqxmd.com/read/29415867/time-course-of-improvement-after-re-repair-procedure-for-vpi-management
#19
Ahmed Elsherbiny, Meghan Amerson, Laura Sconyers, John H Grant
OBJECTIVES: Palatal re-repair aims to improve velar function by retro-positioning the levator veli palatini muscles. The surgery includes extensive dissection, leading to tissue edema and scar formation which may need time to remodel. Together with the change of muscle orientation and tension, it is expected that a period of time is needed to reach the final functional performance. This study attempts to determine how much time is required to reach the optimum performance of the palate after re-repair...
February 5, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29387661/patterns-and-grade-of-velopharyngeal-closure-in-candidates-for-adenotonsillectomy
#20
Mohammad-Waheed El-Anwar, Ezzeddin El-Sheikh, Nasser El-Nakeb
Introduction: The most common type of velopharyngeal valve (VPV) closure is a matter of controversy. The aim of this study was to estimate the most common type of VPV closure, including identification of the type and grade of VPV closure among Egyptian children. Materials and Methods: This study included patients who were candidates for adenotonsillectomy. In these cases, video-nasoendoscopy and speech assessment were performed prior to surgery in addition to otorhinolaryngology examination and preoperative laboratory tests...
January 2018: Iranian Journal of Otorhinolaryngology
keyword
keyword
31245
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"