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https://www.readbyqxmd.com/read/28326707/-morphological-classification-and-velopharyngeal-function-analysis-of-submucous-cleft-palate-patients
#1
Yin Heng, Guo Chunli, Shi Bing, Li Yang, Li Jingtao
OBJECTIVE: To enhance the accuracy in diagnosis and management of submucous cleft palate via a thorough analysis of its anatomical and functional details. METHODS: Two hundred seventy-six submucous cleft palate cases from 2008 to 2014 were retrospectively investigated. Subgroup analysis were performed on the basis of preoperative velopharyngeal function, palatal morphology, cleft lip concurrence, and patient motives for treatment. RESULTS: Among the included cases, 96 (34...
October 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28264992/crispr-cas-and-contact-dependent-secretion-systems-present-on-excisable-pathogenicity-islands-with-conserved-recombination-modules
#2
Megan R Carpenter, Sai S Kalburge, Joseph D Borowski, Molly C Peters, Rita R Colwell, E Fidelma Boyd
Pathogenicity islands (PAIs) are mobile integrated genetic elements that contain a diverse range of virulence factors. PAIs integrate into the host chromosome at a tRNA locus that contains their specific bacterial attachment site, attB, via integrase mediated site-specific recombination generating attL and attR sites. We identified conserved recombination modules (integrases and att sites) previously described in choleragenic V. cholerae PAIs but with novel cargo genes. Clustered regularly interspaced short palindromic repeat (CRISPR)-associated proteins (Cas proteins) and a type VI secretion system (T6SS) gene cluster were identified at the Vibrio Pathogenicity Island-1 (VPI-1) insertion site in nineteen V...
March 6, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28256095/effect-of-visceral-pleural-invasion-on-the-prognosis-of-patients-with-lymph-node-negative-non-small-cell-lung-cancer
#3
Dan Tian, Yuquan Pei, Qingfeng Zheng, Jianzhi Zhang, Shaolei Li, Xing Wang, Dongmei Lin, Yue Yang
BACKGROUND: Visceral pleural invasion (VPI) is an adverse prognostic factor in non-small cell lung cancer (NSCLC); however, its effect in relation to tumor size remains under debate. To better understand the prognostic impact and potential consequences for staging, we examined correlations between VPI and clinicopathologic characteristics in patients with NSCLC, particularly those with lymph node negative NSCLC. METHODS: We retrospectively analyzed 813 cases of radically resected NSCLC treated in our institution between December 2005 and December 2011...
March 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28252393/automatic-measurement-of-spine-curvature-on-3-d-ultrasound-volume-projection-image-with-phase-features
#4
Guang-Quan Zhou, Weiwei Jiang, Ka-Lee Lai, Yong-Ping Zheng
This paper presents an automated measurement of spine curvature by using prior knowledge on vertebral anatomical structures in ultrasound volume projection imaging (VPI). This method can be used in scoliosis assessment with free-hand 3-D ultrasound imaging. It is based on the extraction of bony features from VPI images using a newly proposed two-fold thresholding strategy, with information of the symmetric and asymmetric measures obtained from phase congruency. The spinous column profile is detected from the segmented bony regions, and it is further used to extract a curve representing spine profile...
February 24, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28249942/quantifying-tumour-vascularity-in-non-luminal-breast-cancers
#5
Maria Ryssdal Kraby, Signe Opdahl, Lars A Akslen, Anna M Bofin
AIMS: Microvessel density (MVD), proliferating MVD (pMVD) and vascular proliferation index (VPI) are methods used to quantify tumour vascularity in histopathological sections. In this study, we assessed MVD, pMVD and VPI in non-luminal subtypes of breast cancer. Differences between subtypes were studied, and the prognostic value of each method was assessed. METHODS: All non-luminal subtypes (61 basal phenotype (BP), 60 human epidermal growth factor receptor 2 (HER2) type and 30 five negative phenotype (5NP)) were selected from a series comprising 909 cases of breast cancer...
March 1, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28220643/extent-of-visceral-pleural-invasion-and-the-prognosis-of-surgically-resected-node-negative-non-small-cell-lung-cancer
#6
Yangki Seok, Ji Yun Jeong, Eungbae Lee
BACKGROUND: Visceral pleural invasion (VPI) is generally considered a poor prognostic factor in non-small cell lung cancer (NSCLC). VPI is defined as penetration beyond the elastic layer of visceral pleura (PL1), including the visceral pleural surface without the involvement of adjacent structures (PL2) by cancer cells. The aim of this study was to evaluate the influence of the extent of VPI on NSCLC prognosis. METHODS: This was a retrospective study of 90 patients with resected node-negative NSCLC with VPI...
February 21, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28218552/scandcleft-randomised-trials-of-primary-surgery-for-unilateral-cleft-lip-and-palate-2-surgical-results
#7
Jorma Rautio, Mikael Andersen, Stig Bolund, Jyri Hukki, Hallvard Vindenes, Peter Davenport, Kjartan Arctander, Ola Larson, Anders Berggren, Frank Åbyholm, David Whitby, Alan Leonard, Jan Lilja, Erik Neovius, Anna Elander, Arja Heliövaara, Phil Eyres, Gunvor Semb
BACKGROUND: Longstanding uncertainty surrounds the selection of surgical protocols for unilateral cleft lip and palate, and randomised trials have only rarely been performed. The Scandcleft Project consists of three trials commenced in 1997 involving ten centres in Denmark, Finland, Norway, Sweden, and the UK. Three groups of centres tested a newly-defined common technique for palatal repair (Arm A) against their local protocols (Arms B, C, D). Arm A was familiar to most of the surgeons in Trial 1, but not to the surgeons in the other Trials...
February 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28160864/inulin-type-fructan-and-infusion-of-artemisia-vulgaris-protect-the-liver-against-carbon-tetrachloride-induced-liver-injury
#8
Marília Locatelli Corrêa-Ferreira, Maria Helena Verdan, Francislaine Aparecida Dos Reis Lívero, Larissa Favaretto Galuppo, José Ederaldo Queiroz Telles, Maria Élida Alves Stefanello, Alexandra Acco, Carmen Lúcia de Oliveira Petkowicz
BACKGROUND: Infusions of aerial parts of Artemisia vulgaris L. (Asteraceae) are used in herbal medicine to treat several disorders, including hepatosis. PURPOSE: Evaluation of in vivo hepatoprotective effects of A. vulgaris infusion (VI) and inulin (VPI; i.e., the major polysaccharide of VI). STUDY DESIGN: The hepatoprotective effect of A. vulgaris extracts on carbon tetrachloride (CCl4)-induced hepatotoxicity and the probable mechanism involved in this protection were investigated in mice...
January 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28141791/former-very-preterm-infants-show-alterations-in-plasma-amino-acid-profiles-at-a-preschool-age
#9
Anna Posod, Susanne Müller, Irena Odri Komazec, Daniel Dejaco, Ulrike Pupp Peglow, Elke Griesmaier, Sabine Scholl-Bürgi, Daniela Karall, Ursula Kiechl-Kohlendorfer
BACKGROUND: Amino acid analysis is a valuable tool for cardiovascular risk assessment. Preterm infants display plasma amino acid changes in the newborn period. Whether these changes persist is unknown to date. The aim of the present study was to assess whether former very preterm infants (VPI) show alterations in amino acid patterns indicative of an unfavorable cardiovascular risk profile at a preschool age. METHODS: Five- to seven-year-old children born at term or <32 weeks' gestation (VPI) were included in the study...
January 31, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28116979/long-term-incidence-of-velopharyngeal-insufficiency-and-other-sequelae-following-uvulopalatopharyngoplasty
#10
Jessica A Tang, Anna M Salapatas, Lauren B Bonzelaar, Michael Friedman
Objective The aim of this study is to (1) assess incidence of long-term velopharyngeal insufficiency (VPI) and (2) determine other sequelae following classic and modified uvulopalatopharyngoplasty (UPPP and mUPPP) for treatment of obstructive sleep apnea (OSA). Data Sources Medline, PubMed, Cochrane Library database. Review Methods A systematic review was performed following standard Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Original research articles reporting on sequelae of UPPP and mUPPP for treatment of OSA, at a mean of 1 year follow-up, were included...
January 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28112331/-detection-of-parainfluenza-virus-in-immunocompromised-and-immunocompetent-patients-in-a-tertiary-hospital-in-sao-paulo-brazil
#11
Sheila N Parmezan, Clarice Camargo, Aripuanã Watanabe, Patricio Godoy-Martínez, Celso Granato, Nancy Bellei
Parainfluenza virus infections (PIV) were evaluated in patients with mild and severe infections through real time PCR. One thousand and sixty-seven samples were collected from subjects as follows: 233 adult renal transplanted outpatients, 129 children with congenital heart disease, 381 with adult hematopoietic stem cell patients and 324 hospitalized patients suspected of influenza A (H1N1) pdm09 infection. PIV was detected in 74 (6.9%) samples. VPI-3 was the most frequent (60.8%) and a higher risk was observed for older adults (p = 0...
October 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28088400/hospitalizations-for-respiratory-syncytial-virus-and-vaccine-preventable-infections-in-the-first-2-years-after-pediatric-liver-transplant
#12
Amy G Feldman, Shikha S Sundaram, Brenda L Beaty, Allison Kempe
OBJECTIVES: To examine in liver transplant recipients at centers participating in the Pediatric Health Information System dataset the number of hospitalizations for respiratory syncytial virus (RSV) and vaccine-preventable infections (VPIs) in the first 2 years after transplantation, morbidity and mortality associated with these hospitalizations, and costs associated with these hospitalizations. STUDY DESIGN: A retrospective cohort study of patients <18 years of age who underwent liver transplantation at a Pediatric Health Information System center between January 1, 2004, and December 31, 2012...
March 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28033190/modified-superior-based-pharyngeal-flap-is-effective-in-treatment-of-velopharyngeal-insufficiency-regardless-of-the-preoperative-closure-pattern
#13
Omer Ekin, Mert Calis, Mavis Emel Kulak Kayikci, Mehtap Icen, Riza Onder Gunaydin, Figen Ozgur
Velopharyngeal insufficiency (VPI) is certainly one of the most important problems confronted after cleft palate repairs. In this study, it was aimed to evaluate the preoperative and postoperative speaking results of patients who underwent modified superior-based pharyngeal flap. Sixty-six children who underwent modified superiorly based pharyngeal flap for treatment of VPI between 2005 and 2013 were retrospectively reviewed. The study population was evaluated in 2 distinctive groups depending on their preoperative velopharyngeal closure pattern as: coronal closure pattern or noncoronal closure patterns (ie, circular, sagittal with or without the presence of a Passavant ridge)...
March 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28025442/clinical-efficacy-of-a-1-matricaria-chamomile-l-mouthwash-and-0-12-chlorhexidine-for-gingivitis-control-in-patients-undergoing-orthodontic-treatment-with-fixed-appliances
#14
Paula Goes, Caio S Dutra, Mário R P Lisboa, Delane V Gondim, Renata Leitão, Gerly A C Brito, Rodrigo O Rego
This pilot study evaluated the clinical efficacy of a mouthwash containing 1% Matricaria chamomilla L. (MTC) extract in reducing gingival inflammation and plaque formation in patients undergoing orthodontic treatment with fixed appliances. This randomized, double-blind, placebo-controlled study enrolled a total of 30 males and females (age, 10-40 years) with fixed orthodontic appliances and a minimum of 20 natural teeth. The participants were allocated to three groups (n = 10 each) and asked to rinse with 15 mL of a placebo, 0...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/27999606/traditional-chinese-medicine-qpyf-as-preventive-treatment-for-clostridium-difficile-associated-diarrhea-in-a-mouse-model
#15
Guo Ya-Nan, Wang Jun, Zhang Hao-Jun, Jia Hong-Bing, Li Ping, Liu Xin-Zhu
Traditional Chinese medicine QPYF has a good effect for treating antibiotic-associated diarrhea in clinical practice. The aim of this study is to test its efficacy to prevent Clostridium difficile associated diarrhea (CDAD) in a mouse model. C57BL/6 mice were infected with Clostridium difficile VPI 10463 after exposure to antimicrobial mixture. QPYF was administered from 7 days prior to Clostridium difficile infection to 20 days after infection, and its effect was compared with no treatment and receiving placebo...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27993377/recurrence-pattern-of-pathologic-stage-i-lung-adenocarcinoma-with-visceral-pleural%C3%A2-invasion
#16
Dhihintia Jiwangga, Sukki Cho, Kwhanmien Kim, Sanghoon Jheon
BACKGROUND: Visceral pleural invasion (VPI) is well known to be a poor prognostic factor in lung adenocarcinoma. There were few studies reporting postoperative recurrence pattern in lung adenocarcinoma with VPI. This study was to evaluate the clinical effect of VPI on recurrence pattern in pathologic stage I lung adenocarcinoma after curative resection. METHODS: Among 574 patients with pathologic stage I lung adenocarcinoma after complete resection between 2003 and 2012, the clinicopathologic characteristics of 89 patients (16%) who had recurrence were retrospectively reviewed...
December 16, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27976762/the-total-and-the-differential-mean-pore-anisotropy-in-porous-solids-and-the-ranking-of-pores-according-to-zipf-s-law
#17
Antigoni Margellou, Philippos Pomonis
In this work the property of total pore anisotropy in porous solids is introduced. Its calculation is based on a combination of the specific surface area Sp and the specific pore volume Vp estimated via typical nitrogen porosimetry data and tested in two kinds of porous materials: a group of spinels CoAl2O4 with differentiated random porosities and a second group of silicas SiO2 with ordered porosity modulated by the addition of LaFeO3 nanoparticles. Two basic complementary expressions of total pore anisotropy were estimated: (i) the specific total mean pore anisotropy bmean,total = (N·b) ≈ [Sp(3)]/[Vp(2)] corresponding to the total anisotropy value of all N hypothetical similar pores in one gram of a solid with mean size Dmean = 4Vp/Sp and anisotropy b = Ltotal/Dmean...
January 4, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27939039/velopharyngeal-insufficiency-treated-with-levator-muscle-repositioning-and-unilateral-myomucosal-buccinator-flap
#18
Robrecht J H Logjes, Maaike T A van den Aardweg, Meike M J Blezer, Anne M B van der Heul, Corstiaan C Breugem
PURPOSE: Velopharyngeal insufficiency (VPI) is common (20-30%) after cleft palate closure. The myomucosal buccinator flap has become an important treatment option for velopharyngeal insufficiency; however, published studies all use bilateral buccinator flaps. This study assesses outcomes with a unilateral myomucosal buccinator flap that might result in less operating time and might prevent the need of a bite block and an extra procedure for division of the flap pedicle at a later stage...
January 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27845364/a-genomic-island-in-vibrio-cholerae-with-vpi-1-site-specific-recombination-characteristics-contains-crispr-cas-and-type-vi-secretion-modules
#19
Maurizio Labbate, Fabini D Orata, Nicola K Petty, Nathasha D Jayatilleke, William L King, Paul C Kirchberger, Chris Allen, Gulay Mann, Ankur Mutreja, Nicholas R Thomson, Yan Boucher, Ian G Charles
Cholera is a devastating diarrhoeal disease caused by certain strains of serogroup O1/O139 Vibrio cholerae. Mobile genetic elements such as genomic islands (GIs) have been pivotal in the evolution of O1/O139 V. cholerae. Perhaps the most important GI involved in cholera disease is the V. cholerae pathogenicity island 1 (VPI-1). This GI contains the toxin-coregulated pilus (TCP) gene cluster that is necessary for colonization of the human intestine as well as being the receptor for infection by the cholera-toxin bearing CTX phage...
November 15, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27787538/injection-pharyngoplasty-with-autologous-fat-as-treatment-for-stress-velopharyngeal-insufficiency-in-brass-and-woodwind-musicians
#20
Mausumi N Syamal, Paul C Bryson
Importance: Stress velopharyngeal insufficiency (SVPI) is an uncommon but often career-threatening condition affecting professional brass and woodwind musicians. Objectives: To review the evaluation of and treatment for SVPI in professional musicians with lipoinjection to the posterior pharyngeal wall. Design, Setting, and Participants: A retrospective medical record and literature review. Two professional musicians with SVPI treated with autologous lipoinjection to the posterior pharyngeal wall were included...
February 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
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