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Zijie Wang, Sahila Perananthan, Samitha D Panangala, John P Ferraris, Kenneth J Balkus
Wrinkled mesoporous silica (WMS) has been shown to be a promising material for catalysis and drug delivery. The WMS possesses a unique wrinkled structure with conical shaped pores radiating from the center to the surface of each particle. Lanthanum oxide was supported on wrinkled mesoporous silica as a hard template for the synthesis of graphitic carbon. The resulting carbon material retains the unique wrinkled structure and has high surface area (∼879 m2/g) as well as graphitic walls which were observed by transmission electron microscopy...
January 1, 2018: Journal of Nanoscience and Nanotechnology
G Kokolakis, L von Eichel, M Ulrich, J Lademann, T Zuberbier, M A Hofmann
INTRODUCTION: Fractionated radiofrequency (RF) tissue tightening is an alternative method to fractionated laser treatment of skin wrinkling, laxity and acne scars, with reduced risk of scarring or persistent pigmentation. The aim of this study was to evaluate and quantify the wound healing process after RF treatment. MATERIALS AND METHODS: 12 patients were treated with a 64-pin fractional bipolar RF device with 60 mJ/pin applied energy. Confocal laser scanning microscopy (CLSM) examination was performed on day 1, day 2, day 7 and day 14 after treatment...
May 15, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Joel L Cohen, Arthur Swift, Nowell Solish, Steve Fagien, Dee Anna Glaser
Background: OnabotulinumtoxinA and hyaluronic acid are effective in improving moderate-to-severe facial wrinkles and folds, with treatment selection traditionally based upon facial area. Objective: This prospective, multicenter, open-label, crossover study evaluated physician-rated efficacy and patient-rated outcomes following moderate-to-severe facial wrinkles and folds treatment with onabotulinumtoxinA and hyaluronic acid. Methods: 152 subjects (25-65 years) were randomized (1:1) to a treatment-sequence of onabotulinumtoxinA/hyaluronic acid or hyaluronic acid/onabotulinumtoxinA, with initial treatment administered on Day 1 and 6 additional visits: Week 2 (touch-up); Week 4 (crossover); Week 6 (touch-up); and Weeks 8, 12, and 24 (follow-up)...
May 11, 2018: Aesthetic Surgery Journal
Peeyush P Sharma, Dave Krishan Sharma, Andrew Carr
INTRODUCTION: The emergence of hyaluronic acid dermal fillers with lidocaine has transformed the minimally invasive treatment of wrinkles, lines and folds of the face. Patients can be treated quickly, painlessly and without the need for large doses of lidocaine. Therefore, it is important to scientifically evaluate the merits of lidocaine-containing products over those without. METHODS: The two products, with (UJU) and without lidocaine (UJ), were randomly injected into nasolabial folds of 75 healthy volunteers with varying skin types in a split face study, age ranging 26-60 years...
May 14, 2018: Aesthetic Plastic Surgery
Eyal Karzbrun, Aditya Kshirsagar, Sidney R Cohen, Jacob H Hanna, Orly Reiner
Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously due to compression forces arising during differential swelling, but these ideas have not been tested in a living system. Here, we report the appearance of surface wrinkles during the in vitro development and self-organization of human brain organoids in a micro-fabricated compartment that supports in situ imaging over a timescale of weeks...
May 2018: Nature Physics
Philip R Cohen
Genital rejuvenation is applicable not only to women (vaginal rejuvenation) but also to men (scrotal rejuvenation). There is an increased awareness, reflected by the number of published medical papers, of vaginal rejuvenation; however, rejuvenation of the scrotum has not received similar attention in the medical literature. Scrotal rejuvenation includes treatment of hair-associated scrotal changes (alopecia and hypertrichosis), morphology-associated scrotal changes (wrinkling and laxity), and vascular-associated scrotal changes (angiokeratomas)...
March 13, 2018: Curēus
K Lee, M Kim, K Kim
BACKGROUND: Skin surface evaluation has been studied using various imaging techniques. However, all these studies had limited impact because they were performed using visual exam only. To improve on this scenario with haptic feedback, we propose 3D reconstruction of the skin surface using a single image. Unlike extant 3D skin surface reconstruction algorithms, we utilize the local texture and global curvature regions, combining the results for reconstruction. MATERIALS AND METHODS: The first entails the reconstruction of global curvature, achieved by bilateral filtering that removes noise on the surface while maintaining the edge (ie, furrow) to obtain the overall curvature...
May 11, 2018: Skin Research and Technology
Chenglong Wang, Sisi Luan, Adriana C Panayi, Minqiang Xin, Bobin Mi, Jie Luan
BACKGROUND: Hyaluronic acid (HA) gel is a widely used dermal filler for the correction facial volume loss. The incorporation of lidocaine with HA provides a pain-relieving alternative for individuals considering facial rejuvenation. The aim of this systematic review and meta-analysis is to compare the effectiveness and safety of HA with lidocaine (HAL) with that of HA without lidocaine for the treatment of nasolabial folds (NLFs). METHODS: Studies were identified using the electronic databases PubMed, Embase, Cochrane Central Register of Controlled Trials and Web of Science from inception up to January 2018...
May 8, 2018: Aesthetic Plastic Surgery
Fudong Li, Honghao Hou, Jie Yin, Xuesong Jiang
Dynamic micro/nanopatterns provide an effective approach for on-demand tuning of surface properties to realize a smart surface. We report a simple yet versatile strategy for the fabrication of near-infrared (NIR) light-responsive dynamic wrinkles by using a carbon nanotube (CNT)-containing poly(dimethylsiloxane) (PDMS) elastomer as the substrate for the bilayer systems, with various functional polymers serving as the top stiff layers. The high photon-to-thermal energy conversion of CNT leads to the NIR-controlled thermal expansion of the elastic CNT-PDMS substrate, resulting in dynamic regulation of the applied strain (ε) of the bilayer system by the NIR on/off cycle to obtain a reversible wrinkle pattern...
April 2018: Science Advances
Taisiya Sigaeva, Robert Mangan, Luigi Vergori, Michel Destrade, Les Sudak
We study what is clearly one of the most common modes of deformation found in nature, science and engineering, namely the large elastic bending of curved structures, as well as its inverse, unbending, which can be brought beyond complete straightening to turn into eversion. We find that the suggested mathematical solution to these problems always exists and is unique when the solid is modelled as a homogeneous, isotropic, incompressible hyperelastic material with a strain-energy satisfying the strong ellipticity condition...
April 2018: Proceedings. Mathematical, Physical, and Engineering Sciences
Y Zhao, C Yang, X Chen, M Peng, X Chen, D Zeng
BACKGROUND: The structural integrity of a spermatozoon is very important for the processes of fertilization and embryo development. OBJECTIVE: To provide valuable data for developing better cryopreservation techniques for shrimp sperm. MATERIALS AND METHODS: Using scanning electron microscopy and transmission electron microscopy, we examined the morphological alteration of Litopenaeus vannamei sperm after cryopreservation with different concentrations of dimethylsulfoxide (DMSO)...
September 2017: Cryo Letters
Banu Yurekli, Nilufer Ozdemir Kutbay, Canan Altay, Sadiye Mehtat Unlu, Sait Sen, Huseyin Onay, Tahir Atik, Baris Akinci
PURPOSE: To describe an interesting subtype of familial partial lipodystrophy (FPLD). METHODS: The phenotype of this distinctive FPLD subtype was studied in three Turkish female siblings. RESULTS: Mutation testing was negative for the genes associated with lipodystrophy syndromes. In MRI studies, fat loss was prominent in the posterior aspects of the proximal lower limbs, whilst some fat was preserved in the anterior, medial and lateral aspects...
May 7, 2018: Endocrine Research
Bing Deng, Juanxia Wu, Shishu Zhang, Yue Qi, Liming Zheng, Hao Yang, Jilin Tang, Lianming Tong, Jin Zhang, Zhongfan Liu, Hailin Peng
Corrugation is a ubiquitous phenomenon for graphene grown on metal substrates by chemical vapor deposition, which greatly affects the electrical, mechanical, and chemical properties. Recent years have witnessed great progress in controlled growth of large graphene single crystals; however, the issue of surface roughness is far from being addressed. Here, the corrugation at the interface of copper (Cu) and graphene, including Cu step bunches (CuSB) and graphene wrinkles, are investigated and ascribed to the anisotropic strain relaxation...
May 2, 2018: Small
Li Huang, Dan Zhang, Fei-Hu Zhang, Zhi-Hong Feng, Yu-Dong Huang, Yang Gan
For supported graphene, reliable differentiation and clear visualization of distinct graphene layers and fine features such as wrinkles are essential for revealing the structure-property relationships for graphene and graphene-based devices. Scanning electron microscopy (SEM) has been frequently used for this purpose where high-quality image contrast is critical. However, it is surprising that the effect of key imaging parameters on the image contrast has been seriously undermined by the graphene community...
May 2, 2018: Small
Hsin-Hui Huang, K Kanishka H De Silva, G R A Kumara, Masamichi Yoshimura
Hydrothermal reduction is a promising approach for graphene oxide (GO) reduction since it is environmentally friendly, simple, and cost effective. We present a detailed study of structural changes occurring in graphene oxide during the reduction process. The correlations between the interlayer spacing, chemical states, work functions, surface morphology, level of disorders, the number of layers, and processing time are elucidated. The results reveal that GO flakes remain in the early stage of the reduction process and that they are fully reduced after a 4-h hydrothermal treatment...
May 1, 2018: Scientific Reports
Anna Jaros, Malwina Zasada, Elżbieta Budzisz, Renata Dębowska, Monika Gębczyńska-Rzepka, Helena Rotsztejn
BACKGROUND: Ascorbic acid is a substance with confirmed anti-free-radical properties. It triggers the collagen synthesis, has a depigmenting effect and seals blood vessels. All these properties have a significant effect of the skin's appearance. The characteristic traits of capillary skin include telangiectasias as well as erythema, which might consolidate in the future, along with the feeling of burning and increased skin sensitivity. OBJECTIVES: Study and evaluation of selected parameters of capillary skin after the application of 5% vitamin C concentrate throughout the period of 6 weeks with the use of instrumental tests and questionnaires...
April 30, 2018: Journal of Cosmetic Dermatology
M Dąbrowska, A Mielcarek, I Nowak
BACKGROUND: Evaluation of skin condition on the basis of parametrization and objective measurements of the parameters has become obligatory. The aim of this study was to assess sex-related changes in skin topography and structure using the skin testing equipment. MATERIALS AND METHODS: The study was carried out on the group of 40 volunteers (20 females and 20 males) of the mean age 24 ± 3 years. The skin parameters were measured using 3 devices: Visioscan®  VC 98 (skin topography), Visioline® VL 650 (skin macro relief) and Ultrascan UC22 (ultrasound imaging of the skin)...
April 29, 2018: Skin Research and Technology
Jinxiu Zhao, Xiang Ren, Qingzhi Han, Dawei Fan, Xu Sun, Xuan Kuang, Qin Wei, Dan Wu
Here, we report the in situ electrochemical conversion of NiCr2O4 on Ni foam prepared using a hydrothermal strategy to give ultra-thin wrinkled NiOOH-NiCr2O4 amorphous-crystalline nanosheets on Ni foam (NiOOH-NiCr2O4/NF) via anode oxidation in 1.0 M KOH. Owing to the coordination of NiCr2O4 and NiOOH, NiOOH-NiCr2O4/NF shows superior catalytic activity toward the oxygen evolution reaction (OER) with the demand of overpotential as low as 271 mV to drive a geometrical current density of 20 mA cm-2 under alkaline conditions...
April 30, 2018: Chemical Communications: Chem Comm
Bruna Romana-Souza, Welker Silva-Xavier, Andréa Monte-Alto-Costa
Stress-induced oxidative damage and the inflammatory response lead to degradation of collagen and elastic fibers and wrinkle formation. Topical retinol (or vitamin A) can be a strategy to attenuate the effects of stress in skin since it promotes collagen and elastic fiber production and reduces protease synthesis. This study investigated the effect of topical retinol in stressed human skin using in vivo and ex vivo models. Human skin explants were treated with high levels of epinephrine (as observed in stressed patients) and topically with retinol for 13 days...
April 28, 2018: Experimental Dermatology
F Ursin, F Steger, C Borelli
BACKGROUND: Recipes for peelings date back to medical texts of old Egypt. The oldest medical papyri contain recipes for "improving beauty of the skin" and "removing wrinkles" by use of agents like salt and soda. The Egyptian Queen Cleopatra (69-30 BC) is said to have taken bathes in donkey's milk in order to improve the beauty of her skin. However, little is known about other agents and peeling applications in later Greek medical textbooks. OBJECTIVE: We will discover new agents and describe ancient peeling applications...
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
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