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https://www.readbyqxmd.com/read/28527185/surface-heparinization-and-blood-compatibility-modification-of-small-intestinal-submucosa-sis-for-small-caliber-vascular-regeneration
#1
Bensong Han, Feng Xue, Cunyi Fan, Xiumei Mo
OBJECTIVES: This study aims to investigate the small intestinal submucosal (SIS) surface after heparinization with the hypothermia plasma technique, to improve the blood compatibility of SIS, and to explore the possibility of construction of small-caliber vascular grafts with modified SIS scaffolds in vivo. METHODS: SIS films prepared from jejunums of pigs were processed for surface treatment at different time periods with the argon plasma initiation technique under vacuum, and were then immediately immersed in 4% (m/v) heparin sodium solution for 24-h heparinization...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28526633/facial-skin-rejuvenation-by-autologous-dermal-microfat-transfer-in-photoaged-patients-clinical-evaluation-and-skin-surface-digital-profilometry-analysis
#2
Angelo Trivisonno, Alfredo Rossi, Massimo Monti, Donato Di Nunno, Christophe Desouches, Claudio Cannistra, Gabriele Toietta
Cumulative long-term exposure to solar ultraviolet radiation promotes premature skin aging characterized by wrinkle formation and reduced skin elasticity. In this study, we assessed whether microfat transfer could improve dermal and subcutaneous tissue thickness loss associated with photoaging. Twenty-one patients affected by facial photoaging (photodamage grade II-IV; age range 35-62 years; 19 females, 2 males; all of Caucasian origin) were treated using minimally invasive autologous dermal white fat transfer harvested with a recently designed microcannula...
April 22, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28524250/one-plant-many-uses-a-review-of-the-pharmacological-applications-of-morinda-citrifolia
#3
REVIEW
Mylena Andréa Oliveira Torres, Isadora de Fátima Braga Magalhães, Renata Mondêgo-Oliveira, Joicy Cortez de Sá, Alessandra Lima Rocha, Ana Lucia Abreu-Silva
Morinda citrifolia, also known as noni, is commonly used in popular medicine in Brazil. Many parts of the noni tree are utilized in such practices, including the roots, leaves and seeds. Through a search of online databases, the present article reviews 92 research studies on the biological actions of M. citrifolia. The paper will discuss the therapeutic effects of noni and its compounds in a variety of forms of presentation, focusing on studies that support its traditional use. A large and diverse number of properties were identified, which were divided into immunostimulatory, antitumor, antidiabetic, anti-obesity, antibacterial and anti-septic, antifungal, antiviral, leishmanicidal, antiinflammatory, antinociceptive and analgesic, antioxidant, neuroprotective, wound healing, antiallergic, antiangiogenic, antiemetic and anti-nausea, anti-gastric ulcer and oesophagitis, anthelmintic, antimutagenic, antipsychotic, anxiolytic, photoprotective, anti-wrinkle and periodontal tissue regeneration activities...
May 19, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28521085/wrinkling-and-folding-on-patched-elastic-surfaces-modulation-of-the-chemistry-and-pattern-size-of-microwrinkled-surfaces
#4
Aurora Nogales, Adolfo Del Campo, Tiberio Ezquerra, Juan Rodriguez-Hernandez
An unconventional strategy is proposed that takes advantage of localized high-deformation areas, referred to as folded wrinkles, to produce microstructured elastic surfaces with precisely controlled pattern dimensions and chemical distribution. For that purpose, elastic PDMS substrates were pre-stretched to a different extent and oxidized in particular areas using a mask. When the stretching was removed and the PDMS substrate exhibited out-of-plane deformations that largely depend on the applied pre-stretching...
May 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28520639/wrinkled-vascularized-retinal-pigment-epithelium-detachment-prognosis-after-intravitreal-anti-vegf-therapy
#5
Delphine Lam, Oudy Semoun, Rocio Blanco-Garavito, Camille Jung, Diem T Nguyen, Eric H Souied, Gerard Mimoun
BACKGROUND/PURPOSE: Neovascular age-related macular degeneration (nAMD) is frequently associated with vascularized pigment epithelial detachment (v-PED). We observed a peculiar characteristic of v-PED characterized by small lacy folds of the retinal pigment epithelium, appearing as a wrinkled PED (w-PED) on spectral domain optical coherence tomography (SD-OCT). Our purpose was to describe the visual prognosis and number of intravitreal injections in w-PED compared with non-w-PED. METHODS: In this retrospective, case-control series, we reviewed retrospectively medical records of 52 eyes of 51 patients who were consecutively included between November 1 and 30, 2015 with a previous minimum 3-year follow-up...
May 16, 2017: Retina
https://www.readbyqxmd.com/read/28517009/stress-induced-surface-instabilities-and-defects-in-thin-films-sputter-deposited-on-compliant-substrates
#6
Timothy Ibru, Kyriaki Kalaitzidou, J Kevin Baldwin, Antonia Antoniou
Existing analyses predict that thin metal films deposited on compliant substrates are subject to a variety of surface instabilities, such as wrinkles, folds, creases, etc., that become more prominent with increased compressive residual stress. Under compressive stress, cracks have been assumed to form only when the interfacial strength is weak, allowing the film to detach from the substrate. In this work, we demonstrate that cracks also form on surfaces under compressive mismatch strain when the interface is strong...
May 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28516384/a-mutant-in-the-csdet2-gene-leads-to-a-systemic-brassinosteriod-deficiency-and-super-compact-phenotype-in-cucumber-cucumis-sativus-l
#7
Shanshan Hou, Huanhuan Niu, Qianyi Tao, Shenhao Wang, Zhenhui Gong, Sen Li, Yiqun Weng, Zheng Li
A novel dwarf cucumber mutant, scp-2, displays a typical BR biosynthesis-deficient phenotype, which is due to a mutation in CsDET2 for a steroid 5-alpha-reductase. Brassinosteroids (BRs) are a group of plant hormones that play important roles in the development of plant architecture, and extreme dwarfism is a typical outcome of BR-deficiency. Most cucumber (Cucumis sativus L.) varieties have an indeterminate growth habit, and dwarfism may have its value in manipulation of plant architecture and improve production in certain production systems...
May 17, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28513130/anisotropic-friction-of-wrinkled-graphene-grown-by-chemical-vapor-deposition
#8
Fei Long, Poya Yasaei, Wentao Yao, Amin Salehi-Khojin, Reza Shahbazian-Yassar
Wrinkle structures are commonly seen on graphene grown by chemical vapor deposition (CVD) method due to the different thermal expansion coefficient between graphene and its substrate. Despite the intensive investigations focusing on the electrical properties, the nano-tribological properties of wrinkles and the influence of wrinkle structures on the wrinkle free graphene remain less understood. Here, we report the observation of anisotropic nanoscale frictional characteristics depending on the orientation of wrinkles in CVD-grown graphene...
May 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28509312/histological-immunohistochemical-and-ultrastructural-study-of-secondary-compressed-spinal-cord-injury-in-a-rat-model
#9
Wafaa S Ramadan, Ghada A Abdel-Hamid, Saleh Al-Karim, Aymn T Abbas
INTRODUCTION: Spinal cord injury (SCI) is a life-disrupting condition in which the first few days are the most critical. Secondary conditions remain the main causes of death for people with SCI. The response of different cell types to SCI and their role at different times in the progression of secondary degeneration are not well understood. The aim of this study was to study the histopathological changes of compressed spinal cord injury (CSCI) in a rat model. MATERIAL AND METHODS: Forty adult male Sprague-Dawley rats were divided into four groups...
2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28508976/idiopathic-collapsing-focal-segmental-glomerulosclerosis-in-an-81-year-old-japanese-woman-a-case-report-and-review-of-the-literature
#10
Jun Yamazaki, Eriko Kanehisa, Wakaba Yamaguchi, Jiro Kumagai, Kiyotaka Nagahama, Hajime Fujisawa
Focal segmental glomerulosclerosis (FSGS) is classified into five variants, with the collapsing variant being the most rare. Collapsing FSGS is characterized by a black racial predominance and is often associated with human immunodeficiency virus-associated nephropathy. However, the number of idiopathic cases is increasing and the presentation of non-black patients becoming more routine. Our analysis of 15 previous reports investigating FSGS variants shows that the collapsing variant accounts for 10.6 % of FSGS cases and its average age of onset is 32 years old...
November 2016: CEN Case Reports
https://www.readbyqxmd.com/read/28507390/high-quality-pvd-graphene-growth-by-fullerene-decomposition-on-cu-foils
#11
J Azpeitia, G Otero-Irurueta, I Palacio, J I Martinez, N Ruiz Del Árbol, G Santoro, A Gutiérrez, L Aballe, M Foerster, M Kalbac, V Vales, F J Mompeán, M García-Hernández, J A Martín-Gago, C Munuera, M F López
We present a new protocol to grow large-area, high-quality single-layer graphene on Cu foils at relatively low temperatures. We use C60 molecules evaporated in ultra high vacuum conditions as carbon source. This clean environment results in a strong reduction of oxygen-containing groups as depicted by X-ray photoelectron spectroscopy (XPS). Unzipping of C60 is thermally promoted by annealing the substrate at 800ºC during evaporation. The graphene layer extends over areas larger than the Cu crystallite size, although it is changing its orientation with respect to the surface in the wrinkles and grain boundaries, producing a modulated ring in the low energy electron diffraction (LEED) pattern...
August 2017: Carbon
https://www.readbyqxmd.com/read/28505495/generalized-boussinesq-scriven-surface-fluid-model-with-curvature-dissipation-for-liquid-surfaces-and-membranes
#12
Oscar F Aguilar Gutierrez, Edtson E Herrera Valencia, Alejandro D Rey
Curvature dissipation is relevant in synthetic and biological processes, from fluctuations in semi-flexible polymer solutions, to buckling of liquid columns, tomembrane cell wall functioning. We present a micromechanical model of curvature dissipation relevant to fluid membranes and liquid surfaces based on a parallel surface parameterization and a stress constitutive equation appropriate for anisotropic fluids and fluid membranes.The derived model, aimed at high curvature and high rate of change of curvature in liquid surfaces and membranes, introduces additional viscous modes not included in the widely used 2D Boussinesq-Scriven rheological constitutive equation for surface fluids...
May 8, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28504903/hepatocellular-carcinoma-a-wrinkle-in-the-emerging-palliative-care-oncology-paradigm
#13
Christopher D Woodrell, Thomas D Schiano, Nathan E Goldstein
No abstract text is available yet for this article.
May 15, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28504298/bio-inspired-hierarchical-micro-and-nano-wrinkles-obtained-via-mechanically-directed-self-assembly-on-shape-memory-polymers
#14
Senta Schauer, Matthias Worgull, Hendrik Hölscher
Inspired by complex multi-functional leaf and petal surfaces, we introduce a mechanically directed self-assembly process to create linearly oriented micro- and nanosized surface wrinkles in an all-polymer bi-layer system based on a shape-memory polymer substrate. By systematically investigating the influence of coating thickness and substrate programming strain on wrinkle period and height, we reveal how to control the structure size from a few hundred nanometers up to several microns. As a parameter unique to shape memory polymers, we demonstrate that the temperature during the recovery process can also be utilized to tailor the structure dimensions...
May 15, 2017: Soft Matter
https://www.readbyqxmd.com/read/28503261/anti-photoaging-effects-of-angelica-acutiloba-root-ethanol-extract-in-human-dermal-fibroblasts
#15
Min Ah Park, Mi Ja Sim, Young Chul Kim
The effects that ultraviolet rays elicit on collagen synthesis and degradation are the most common causes of wrinkle formation and photo-aging in skin. The objectives of this study were to evaluate the effects of Angelica acutiloba root ethanol extract (AAEE) to promote collagen synthesis and inhibit collagen degradation in human dermal fibroblasts. By examining total polyphenol and flavonoid contents, electron donating ability, radical scavenging activity, and superoxide dismutase-like activity, we found that AAEE exhibited fairly good antioxidant activity...
April 2017: Toxicological Research
https://www.readbyqxmd.com/read/28490897/glutathione-and-its-antiaging-and-antimelanogenic-effects
#16
Sinee Weschawalit, Siriwan Thongthip, Phanupong Phutrakool, Pravit Asawanonda
BACKGROUND: Previous studies showed that supplementation of reduced form of glutathione (GSH, 500 mg/d) has a skin-lightening efficacy in humans. This study was designed to evaluate the influences of both GSH and oxidized form (GSSG), at doses lower than 500 mg/d, on improving skin properties. PATIENTS AND METHODS: A randomized, double-blind, placebo-controlled, parallel, three-arm study was conducted. Healthy female subjects were equally randomized into three groups and took GSH (250 mg/d), GSSG (250 mg/d), or placebo orally for 12 weeks...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28486967/pseudoxanthoma-elasticum
#17
REVIEW
Dominique P Germain
Pseudoxanthoma elasticum (PXE) is a genetic metabolic disease with autosomal recessive inheritance caused by mutations in the ABCC6 gene. The lack of functional ABCC6 protein leads to ectopic mineralization that is most apparent in the elastic tissues of the skin, eyes and blood vessels. The clinical prevalence of PXE has been estimated at between 1 per 100,000 and 1 per 25,000, with slight female predominance. The first clinical sign of PXE is almost always small yellow papules on the nape and sides of the neck and in flexural areas...
May 10, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28485872/new-lasers-and-light-sources-old-and-new-risks
#18
REVIEW
Uwe Paasch, Antje Schwandt, Nikolaus Seeber, Gerd Kautz, Sonja Grunewald, Merete Haedersdal
Recent developments (new wavelengths, treatment concepts, and combinations) in the field of lasers, intense pulsed light (IPL), LED, as well as new energy and light sources have opened up new therapeutic options that extend beyond mere aesthetic indications. Thus, while fractional lasers used to be employed to merely treat wrinkles, the same devices - in the context of laser-assisted drug delivery - have now become important tools in the treatment of scars, field cancerization, and epithelial tumors. The requirements posed to physicians, both with respect to establishing the indication and conducting treatment, have been growing along with the increase in technological complexity as well as the rising number of comorbidities and comedications in a patient population that continues to age...
May 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28481833/air-pump-assisted-graft-centration-graft-edge-unfolding-and-graft-uncreasing-in-young-donor-graft-pre-descemet-endothelial-keratoplasty
#19
Soosan Jacob, Smita Narasimhan, Amar Agarwal, Athiya Agarwal, Saijimol A I
PURPOSE: To assess an air pump-assisted technique for graft centration, graft edge unfolding, and graft uncreasing while performing pre-Descemet endothelial keratoplasty (PDEK) using young donor grafts. METHODS: Continuous pressurized air infusion was used for graft centration, graft edge unfolding, and graft unwrinkling. RESULTS: Ten eyes of 10 patients underwent PDEK with donors aged below 40 years. In all eyes, the donor scrolled into tight scrolls...
May 3, 2017: Cornea
https://www.readbyqxmd.com/read/28479757/premature-ovarian-failure-an-unusual-manifestation-of-systemic-sclerosis
#20
Aruna Nigam, Anupam Prakash, Shikha Sharma, Narendra Kumar
A 31-year-old woman presented with secondary amenorrhoea and inability to conceive, which was of 3 years duration. She had Raynaud's phenomenon for 16 years, primary hypothyroidism for 5 years, digital ulcers for 4 years and skin tightening for 2 years. She had an expressionless face, with loss of wrinkles and restriction of the mouth opening along with flexion contractures of the hands and the terminal digit resorptions. Investigations showed Antinuclear antibodies (ANA) and anti-Scl 70 positivity confirming the presence of systemic sclerosis (SSc)...
January 2017: Journal of Human Reproductive Sciences
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