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https://www.readbyqxmd.com/read/28733999/retinyl-propionate-and-climbazole-combination-demonstrates-clinical-improvement-to-the-appearance-of-hyperpigmentation-and-deep-wrinkling-with-minimal-irritation
#1
Stacy Hawkins, Jean Adamus, Chung-Yi Chiang, Edwin Covell, Jaime O'Leary, Jian-Ming Lee
OBJECTIVE: To evaluate a combination of retinyl propionate and climbazole (RPC) compared to 0.1% retinol for its efficacy, tolerance and aging appearance. METHOD: Forty-five healthy Caucasian females, ages 40-70, with moderately photodamaged facial skin, were recruited for a 16 week randomized, double-blind, IRB approved facial study. The efficacy of RPC treatment was compared to 0.1% retinol, in the same product base formulation, with twice daily, split-face product application...
July 22, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28733805/onabotulinumtoxina-botox-in-the-treatment-of-crow-s-feet-lines-in-japanese-subjects
#2
Kiyonori Harii, Makoto Kawashima, Nobutaka Furuyama, Xiaofang Lei, René Hopfinger, Elisabeth Lee
BACKGROUND: This study evaluated the safety and efficacy of onabotulinumtoxinA in Japanese subjects with crow's feet lines (CFL). METHODS: This phase 3, multicenter, double-blind, randomized study included 2 treatment periods: 6-month placebo-controlled period followed by a 7-month open-label period. In period 1, subjects with moderate to severe CFL received onabotulinumtoxinA 24 U (n = 104) or 12 U (n = 99), or placebo (n = 97). In period 2, placebo subjects switched to onabotulinumtoxinA 24 U or 12 U (double-blind dose)...
July 21, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28731160/adipose%C3%A2-derived-stem-cells-and-hyaluronic-acid-based-gel-compatibility-studied-in-vitro
#3
Jiayan Guo, Shu Guo, Yuxin Wang, Yanqiu Yu
Minimally invasive aesthetic and cosmetic procedures have increased in popularity. Injectable dermal fillers provide soft tissue augmentation, improve facial rejuvenation and wrinkles, and correct tissue defects. To investigate the use of adipose‑derived stem cells integrated with a hyaluronic acid based gel as a dermal filler, the present study used cytotoxicity studies, proliferation studies, adipogenic and osteogenic differentiation, apoptosis assays and scanning electron microscopy. Although hyaluronic acid induced low levels of apoptosis in adipose‑derived stem cells, its significantly promoted proliferation of adipose‑derived stem cells...
July 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28730411/sugary-endosperm-is-modulated-by-starch-branching-enzyme-iia-in-rice-oryza-sativa-l
#4
Yunjoo Lee, Min-Seon Choi, Gileung Lee, Su Jang, Mi-Ra Yoon, Backki Kim, Rihua Piao, Mi-Ok Woo, Joong Hyoun Chin, Hee-Jong Koh
BACKGROUND: Starch biosynthesis is one of the most important pathways that determine both grain quality and yield in rice (Oryza sativa L.). Sugary endosperm, sugary-1 (sug-1), is a mutant trait for starch biosynthesis. Rice plants carrying sug-1 produce grains that accumulate water-soluble carbohydrates instead of starch, even after maturity. Although this trait enhances the diversity of grain quality, sugary endosperm rice has hardly been commercialized due to the severely wrinkled grains and subsequent problems in milling...
December 2017: Rice
https://www.readbyqxmd.com/read/28729661/surface-modification-of-anisotropic-dielectric-elastomer-actuators-with-uni-and-bi-axially-wrinkled-carbon-electrodes-for-wettability-control
#5
Kiwoo Jun, Donggyu Kim, Seunghwa Ryu, Il-Kwon Oh
Interest in soft actuators for next-generation electronic devices, such as wearable electronics, haptic feedback systems, rollable flexible displays, and soft robotics, is rapidly growing. However, for more practical applications in diverse electronic devices, soft actuators require multiple functionalities including anisotropic actuation in three-dimensional space, active tactile feedback, and controllable wettability. Herein, we report anisotropic dielectric elastomer actuators with uni- and bi-axially wrinkled carbon black electrodes that are formed through pre-streching and relaxation processes...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728332/skin-necrosis-with-oculomotor-nerve-palsy-due-to-a-hyaluronic-acid-filler-injection
#6
Jae Il Lee, Seok Joo Kang, Hook Sun
Performing rhinoplasty using filler injections, which improve facial wrinkles or soft tissues, is relatively inexpensive. However, intravascular filler injections can cause severe complications, such as skin necrosis and visual loss. We describe a case of blepharoptosis and skin necrosis caused by augmentation rhinoplasty and we discuss the patient's clinical progress. We describe the case of a 25-year-old female patient who experienced severe pain, blepharoptosis, and decreased visual acuity immediately after receiving a filler injection...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28727038/genetic-correlations-between-wool-traits-and-carcass-traits-in-merino-sheep
#7
S I Mortimer, S Hatcher, N M Fogarty, J H J van der Werf, D J Brown, A A Swan, R H Jacob, G H Geesink, D L Hopkins, J E Hocking Edwards, E N Ponnampalam, K L Pearce, D W Pethick
Genetic correlations between 29 wool production and quality traits and 14 whole carcass measures and carcass component traits were estimated from the Information Nucleus of 8 flocks managed across a range of Australian sheep production environments and genetically linked. Wool data were from over 5,000 Merino progeny born over 5 yr, whereas carcass data were from over 1,200 wether progeny of over 176 sires, slaughtered at about 21 kg carcass weight, on average. Wool traits included yearling and adult records for wool weight, fiber diameter, fiber diameter variation, staple strength, scoured color, and visual scores for breech and body wrinkle...
June 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726993/genetic-parameters-for-wool-traits-live-weight-and-ultrasound-carcass-traits-in-merino-sheep
#8
S I Mortimer, S Hatcher, N M Fogarty, J H J van der Werf, D J Brown, A A Swan, J C Greeff, G Refshauge, J E Hocking Edwards, G M Gaunt
Genetic correlations between 29 wool production and quality traits and live weight and ultrasound fat depth (FAT) and eye muscle depth (EMD) traits were estimated from the Information Nucleus (IN). The IN comprised 8 genetically linked flocks managed across a range of Australian sheep production environments. The data were from a maximum of 9,135 progeny born over 5 yr from 184 Merino sires and 4,614 Merino dams. The wool traits included records for yearling and adult fleece weight, fiber diameter (FD), staple length (SL), fiber diameter CV (FDCV), scoured color, and visual scores for breech and body wrinkle...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726371/multilayer-regulation-of-atomic-boron-nitride-films-to-improve-oxidation-and-corrosion-resistance-of-cu
#9
Siming Ren, Mingjun Cui, Jibin Pu, Qunji Xue, Liping Wang
Boron nitride (BN) monolayer (1L) with high impermeability and resistivity seems to hold promise as a long-term corrosion barrier for Cu at ambient condition, which is supported by recent researches. Here we perform a complete study of the alternating temperature tests (the sample is exposed in air for 30 days and subsequently heated at 200 ℃ for 2 h) and electrochemical measurements on 1L and multilayers BN coated Cu foils. Results imply that the BN coated Cu foils are less oxidized than uncoated Cu foil after alternating temperature tests, regardless of the layers of BN...
July 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28726351/correction-of-horizontal-neck-lines-our-preliminary-experience-with-hyaluronic-acid-fillers
#10
Soo-Keun Lee, Hei Sung Kim
BACKGROUND: There is an increasing trend shifting the esthetic focus downward from the face with a significant number of new treatments aimed at the aging neck. Hyaluronic acid (HA) filler injection is widely performed into the horizontal neck lines in Korea, but there are few reports assessing its effectiveness. OBJECTIVE: We aimed to evaluate the efficacy and safety of HA filler injection in the treatment of horizontal neck lines. PATIENTS AND METHODS: A retrospective chart review was performed on cases of horizontal neck lines treated with HA fillers...
July 20, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28726326/speechless
#11
Nadine T Himelfarb
Bright blue eyes rimmed with deep sun wrinkles, a crown of mousy brown hair that appeared freshly cut by a four-year old with safety scissors, the patient was thin figured, wearing a flannel, yellowed t-shirt peaking from underneath, and a boxy, heavily stained canvas jacket over the shoulders. Old jeans were cinched at the waist by a crackled leather belt. The dirty right foot which lay bare on the stretcher was then thrust at me. The patient pointed angrily at the exposed foot. This article is protected by copyright...
July 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28722730/tunable-in-plane-torsional-strength-of-surface-functionalized-two-dimensional-nanomaterials
#12
Qianling Lin, Yinfeng Li, Haimin Yao
In this paper, the in-plane torsional properties of two dimensional nanomaterials are revealed to be tunable by surface functionalization using molecular dynamics simulations. The torsional strengths of both graphene and graphyne under circular shearing are found to first decrease and then increase anomalously with the increase of the hydrogenation ratio. The minimum strength of such U-shaped strength evolution appears at different hydrogenation ratios H for graphene (H = 50%) and graphyne (H = 70%), demonstrating a correlation between hydrogenation and the unit lattices of 2D nanomaterials...
July 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28722403/wrinkled-few-layer-graphene-as-highly-efficient-load-bearer
#13
Charalampos Androulidakis, Emmanuel Nicholaos Koukaras, Jaroslava Rahova, Krishna Sampathkumar, John Parthenios, Konstantinos Papagelis, Otakar Frank, Costas Galiotis
Multilayered graphitic materials are not suitable as load-bearers due to their inherent weak interlayer bonding (for example, graphite is a solid lubricant in certain applications). This situation is largely improved when two-dimensional (2-D) materials such as a monolayer (SLG) graphene are employed. The downside in these cases is the presence of thermally or mechanically induced wrinkles which are ubiquitous in 2-D materials. Here we set out to examine the effect of extensive large wavelength/ amplitude wrinkling on the stress transfer capabilities of exfoliated simply-supported graphene flakes...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28719599/the-smectic-order-of-wrinkles
#14
Hillel Aharoni, Desislava V Todorova, Octavio Albarrán, Lucas Goehring, Randall D Kamien, Eleni Katifori
A thin elastic sheet lying on a soft substrate develops wrinkled patterns when subject to an external forcing or as a result of geometric incompatibility. Thin sheet elasticity and substrate response equip such wrinkles with a global preferred wrinkle spacing length and with resistance to wrinkle curvature. These features are responsible for the liquid crystalline smectic-like behaviour of such systems at intermediate length scales. This insight allows better understanding of the wrinkling patterns seen in such systems, with which we explain pattern breaking into domains, the properties of domain walls and wrinkle undulation...
July 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28712336/clinical-and-histological-studies-of-suborbital-wrinkles-treated-with-fractional-bipolar-radiofrequency
#15
Jun Huang, Wenyou Yu, Zhen Zhang, Xiaodong Chen, Ewelina Biskup
Fractional bipolar radiofrequency (FRF) has been well established for facial rejuvenation, but there is no report showing its efficacy for the treatment of suborbital wrinkles. The aim of this study was to investigate and objectively evaluate the clinical efficacy and side effects of FRF for the treatment of suborbital wrinkles, including observation of histological changes of the suborbital skin along the therapy. 32 female patients with suborbital wrinkles underwent 3 sessions of FRF at 3-week intervals with a follow-up period of 6 months after treatment...
July 16, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/28709298/direct-numerical-simulation-study-of-statistically-stationary-propagation-of-a-reaction-wave-in-homogeneous-turbulence
#16
Rixin Yu, Andrei N Lipatnikov
A three-dimensional (3D) direct numerical simulation (DNS) study of the propagation of a reaction wave in forced, constant-density, statistically stationary, homogeneous, isotropic turbulence is performed by solving Navier-Stokes and reaction-diffusion equations at various (from 0.5 to 10) ratios of the rms turbulent velocity U^{'} to the laminar wave speed, various (from 2.1 to 12.5) ratios of an integral length scale of the turbulence to the laminar wave thickness, and two Zeldovich numbers Ze=6.0 and 17...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28708795/proposal-of-a-video-recording-system-for-the-assessment-of-bell-s-palsy-methodology-and-preliminary-results
#17
Simonetta Monini, Franco Marinozzi, Francesca Atturo, Fabiano Bini, Silvia Marchelletta, Maurizio Barbara
HYPOTHESIS: To propose a new objective video-recording procedure to assess and monitor over time the severity of facial nerve palsy. BACKGROUND: No objective methods for facial palsy (FP) assessment are universally accepted. METHODS: The face of subjects presenting with different degrees of facial nerve deficit, as measured by the House-Brackmann (HB) grading system, was videotaped after positioning, at specific points, 10 gray circular markers made of a retroreflective material...
July 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28707007/wrinkle-and-crack-dependent-charge-transport-in-a-uniaxially-strained-conducting-polymer-film-on-a-flexible-substrate
#18
Biporjoy Sarkar, Dillip K Satapathy, Manu Jaiswal
We investigate charge transport in poly(3,4-ethylene dioxythiophene) polystyrene sulfonate (PEDOT:PSS) films on functionalized polydimethylsiloxane (PDMS) substrates under varying uniaxial strain up to 16%. Strong anisotropy in transport is observed at a large applied strain (ε > 4%), which is understood in terms of an extrinsic process, involving a change in density of cracks from a few cracks per mm at ε = 4% to >100 cracks per mm at ε = 16%. The quasi-periodic cracks are aligned perpendicular to the stretching direction...
July 14, 2017: Soft Matter
https://www.readbyqxmd.com/read/28702991/self-similar-hierarchical-wrinkles-as-a-potential-multifunctional-smart-window-with-simultaneously-tunable-transparency-structural-color-and-droplet-transport
#19
Gaojian Lin, Prashant Chandrasekaran, Cunjing Lv, Qiuting Zhang, Yichao Tang, Lin Han, Jie Yin
Smart window has immense potential for energy saving in architectural and vehicular applications, while most studies focus on the tunability of single property of optical transmittance. Here we explore harnessing dynamically tunable hierarchical wrinkles for design of a potential multifunctional smart window with combined structural color and water droplet transport control. The self-similar hierarchical wrinkles with both nanoscale and microscale features are generated on a pre-strained poly(dimethylsiloxane) (PDMS) elastomer through sequential strain release and multi-step oxygen plasma treatment...
July 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28697217/expert-consensus-on-absorbable-advanced-suspension-technology-for-facial-tissue-repositioning-and-volume-enhancement
#20
Mark S Nestor, Glynis Ablon, Anneke Andriessen, Julius Few, Michael H Gold, David J Goldberg, Paul Lorenc, Stephen Mandy, Susan H Weinkle
<p>BACKGROUND: Signs of facial aging include wrinkles, loss of subcutaneous volume, decreased tone, texture, and sagging of the skin. The objective of this review is to determine whether facial suspension absorbable sutures are a safe and effective modality for facial rejuvenation.</p> <p>METHOD: A group of US plastic surgeons and dermatologists who practice medical aesthetics convened to review evidence obtained from literature searches and to reach a consensus on clinical practice guidelines for the use of facial absorbable suspension sutures...
July 1, 2017: Journal of Drugs in Dermatology: JDD
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