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https://www.readbyqxmd.com/read/29165404/benefits-of-nut-consumption-on-insulin-resistance-and-cardiovascular-risk-factors-multiple-potential-mechanisms-of-actions
#1
REVIEW
Yoona Kim, Jennifer B Keogh, Peter M Clifton
Epidemiological and clinical studies have indicated that nut consumption could be a healthy dietary strategy to prevent and treat type 2 diabetes (T2DM) and related cardiovascular disease (CVD). The objective of this review is to examine the potential mechanisms of action of nuts addressing effects on glycemic control, weight management, energy balance, appetite, gut microbiota modification, lipid metabolism, oxidative stress, inflammation, endothelial function and blood pressure with a focus on data from both animal and human studies...
November 22, 2017: Nutrients
https://www.readbyqxmd.com/read/29164705/molecular-engineering-of-mn-ii-diamine-diketonate-precursors-for-the-vapor-deposition-of-manganese-oxide-nanostructures
#2
Chiara Maccato, Lorenzo Bigiani, Giorgio Carraro, Alberto Gasparotto, Roberta Seraglia, Jiyeon Kim, Anjana Devi, Gloria Tabacchi, Ettore Fois, Giuseppe Pace, Vito Di Noto, Davide Barreca
Molecular engineering of manganese(II) diamine diketonate precursors is a key issue for their use in the vapor deposition of manganese oxide materials. Herein, two closely related β-diketonate diamine Mn(II) adducts with different fluorine contents in the diketonate ligands are examined. The target compounds were synthesized by a simple procedure and, for the first time, thoroughly characterized by a joint experimental-theoretical approach, to understand the influence of the ligand on their structures, electronic properties, thermal behavior, and reactivity...
November 22, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29164391/association-between-low-diastolic-blood-pressure-and-subclinical-myocardial-injury
#3
George S Waits, Wesley T O'Neal, Pratik B Sandesara, Yabing Li, Amit J Shah, Elsayed Z Soliman
BACKGROUND: Coronary arteries perfuse cardiac myocytes during diastole. We hypothesized that marked lowering of diastolic blood pressure (DBP) is associated with increased risk of subclinical myocardial injury (SC-MI). METHODS: This analysis included 6107 participants without history of cardiovascular disease (CVD) from the third National Health and Nutrition Examination Survey. SC-MI was determined by a validated electrocardiogram-based scoring system. Logistic regression was used to examine the cross-sectional association between DBP (< 70, 70-80 mmHg (reference group), and > 80 mmHg; and per each 10 mmHg decrease, separately) with SC-MI across levels of systolic blood pressure (SBP) (< 120, 120-139, or > 140 mmHg)...
November 21, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29164133/role-of-dietary-antioxidants-in-the-preservation-of-vascular-function-and-the-modulation-of-health-and-disease
#4
REVIEW
Saradhadevi Varadharaj, Owen J Kelly, Rami N Khayat, Purnima S Kumar, Naseer Ahmed, Jay L Zweier
In vascular diseases, including hypertension and atherosclerosis, vascular endothelial dysfunction (VED) occurs secondary to altered function of endothelial nitric oxide synthase (eNOS). A novel redox regulated pathway was identified through which eNOS is uncoupled due to S-glutathionylation of critical cysteine residues, resulting in superoxide free radical formation instead of the vasodilator molecule, nitric oxide. In addition, the redox sensitive cofactor tetrahydrobiopterin, BH4, is also essential for eNOS coupling...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29164077/glucose-variability-for-cardiovascular-risk-factors-in-type-2-diabetes-a-meta-analysis
#5
REVIEW
Shuang Liang, Hang Yin, Chunxiang Wei, Linjun Xie, Hua He, Xiaoquan Liu
Aims: It is consensus that glucose variability (GV) plays an important role in maccomplications of type 2 diabetes, but whether GV has a causal role is not yet clear for cardiovascular disease (CVD). This study sought to explore the effect on GV for CVD risk factors with type 2 diabetes. Methods: The systematic literature search was performed to identify all GV and CVD risk factors, including total cholesterol (TC), LDL cholesterol (LDL-C), triglyceride (TG), HDL cholesterol (HDL-C), Body Mass Index (BMI), waist circumference (WC), High-Sensitivity C-reactive protein (Hs-CRP), Homeostasis model assessment (HOMA) and carotid intima-media thickness (IMT)...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/29163212/regulation-of-skeletal-muscle-plasticity-by-protein-arginine-methyltransferases-and-their-potential-roles-in-neuromuscular-disorders
#6
REVIEW
Derek W Stouth, Tiffany L vanLieshout, Nicole Y Shen, Vladimir Ljubicic
Protein arginine methyltransferases (PRMTs) are a family of enzymes that catalyze the methylation of arginine residues on target proteins, thereby mediating a diverse set of intracellular functions that are indispensable for survival. Indeed, full-body knockouts of specific PRMTs are lethal and PRMT dysregulation has been implicated in the most prevalent chronic disorders, such as cancers and cardiovascular disease (CVD). PRMTs are now emerging as important mediators of skeletal muscle phenotype and plasticity...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29163211/oxidative-stress-in-the-local-and-systemic-events-of-apical-periodontitis
#7
REVIEW
Patricia Hernández-Ríos, Pirkko J Pussinen, Rolando Vernal, Marcela Hernández
Oxidative stress is involved in the pathogenesis of a variety of inflammatory disorders. Apical periodontitis (AP) usually results in the formation of an osteolytic apical lesion (AL) caused by the immune response to endodontic infection. Reactive oxygen species (ROS) produced by phagocytic cells in response to bacterial challenge represent an important host defense mechanism, but disturbed redox balance results in tissue injury. This mini review focuses on the role of oxidative stress in the local and associated systemic events in chronic apical periodontitis...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29162192/does-striving-to-succeed-come-at-a-physiological-or-psychosocial-cost-for-adults-who-experienced-child-maltreatment
#8
Jenalee R Doom, Vivienne M Hazzard, Katherine W Bauer, Cari Jo Clark, Alison L Miller
While striving to succeed in the face of adversity may provide individuals with outward benefits, it may come at a cost to individuals' physical health. The current study examines whether striving predicts greater physiological or psychosocial costs among those who experienced child maltreatment, a stressor that disrupts the caregiving environment and threatens relationship security. Using data from the National Longitudinal Study of Adolescent to Adult Health, we tested whether greater striving after childhood maltreatment would come at a cost, increasing underlying cardiovascular disease (CVD) risk and depressive symptoms despite showing outward success via income and college degree attainment...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29161890/impact-of-physical-activity-on-the-risk-of-cardiovascular-disease-in-middle-aged-and-older-adults-epic-norfolk-prospective-population-study
#9
Sangeeta Lachman, S Matthijs Boekholdt, Robert N Luben, Stephen J Sharp, Soren Brage, Kay-Tee Khaw, Ron Jg Peters, Nicholas J Wareham
Background There is broad consensus that regular physical activity yields major health benefits. However, current guidelines on physical activity are mainly aimed at middle-aged adults. It is unclear whether physical activity also translates into cardiovascular health benefits in older adults. Therefore, we aimed to compare the association between different levels of physical activity and the risk of cardiovascular disease (CVD) in elderly to middle-aged individuals. Methods We analysed data from the EPIC Norfolk prospective population study...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29159932/barriers-to-adopting-a-mediterranean-diet-in-northern-european-adults-at-high-risk-of-developing-cardiovascular-disease
#10
S E Moore, C T McEvoy, L Prior, J Lawton, C C Patterson, F Kee, M Cupples, I S Young, K Appleton, M C McKinley, J V Woodside
BACKGROUND: Strong evidence links the consumption of a Mediterranean diet (MD) with a reduced cardiovascular disease (CVD) risk; however, there is uncertainty as to whether non-Mediterranean regions will adopt this diet. The present qualitative research aimed to investigate attitudes towards a MD in individuals at high CVD risk in a Northern European population. This information is needed to inform development of MD interventions in non-Mediterranean high-risk populations. METHODS: Focus groups (n = 12) were held with individuals at high CVD risk from Northern Europe (≥2 CVD risk factors, aged ≥50 years, no established CVD/type 2 diabetes)...
November 21, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29159526/cardiovascular-disease-in-kidney-transplant-recipients-japan-academic-consortium-of-kidney-transplantation-jack-cohort-study
#11
Masayoshi Okumi, Yoichi Kakuta, Kohei Unagami, Ryoichi Maenosono, Katsunori Miyake, Junpei Iizuka, Toshio Takagi, Hideki Ishida, Kazunari Tanabe
BACKGROUND: The number of kidney transplant recipients (KTRs) from diabetic nephropathy (DN) and with cardiovascular disease (CVD) history has increased worldwide. Nevertheless, epidemiologic evidence of CVD in KTRs remains limited. METHODS: We investigated post-transplant CVD in 1614 adult KTRs between 1990 and 2014. CVD was defined according to the international classification of diseases (ICD-10). All-cause mortality was also investigated. Final follow-up was performed in March 2016...
November 20, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29159378/in-stable-cvd-rivaroxaban-plus-aspirin-reduced-cv-events-and-increased-bleeding-compared-with-aspirin-alone
#12
Steven Borzak
No abstract text is available yet for this article.
November 21, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29157533/cardiorespiratory-fitness-cutoff-points-for-early-detection-of-present-and-future-cardiovascular-risk-in-children-a-2-year-follow-up-study
#13
José Castro-Piñero, Alejandro Perez-Bey, Víctor Segura-Jiménez, Virginia A Aparicio, Sonia Gómez-Martínez, Rocio Izquierdo-Gomez, Ascensión Marcos, Jonatan R Ruiz
OBJECTIVE: To examine the association between cardiorespiratory fitness (CRF) at baseline and cardiovascular disease (CVD) risk in 6- to 10-year-olds (cross-sectional) and 2 years later (8- to 12-year-olds [longitudinal]) and whether changes with age in CRF are associated with CVD risk in children aged 8 to 12 years. PATIENTS AND METHODS: Spanish primary schoolchildren (n=236) aged 6 to 10 years participated at baseline. Of the 23 participating primary schools, 22% (n=5) were private schools and 78% (n=18) were public schools...
November 10, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29157100/imbalanced-plasma-ace-and-ace2-level-in-the-uremic-patients-with-cardiovascular-diseases-and-its-change-during-a-single-hemodialysis-session
#14
Chung-Wei Yang, Li-Che Lu, Chia-Chu Chang, Ching-Chang Cho, Wen-Yeh Hsieh, Chin-Hung Tsai, Yi-Chang Lin, Chih-Sheng Lin
BACKGROUND: The renin-angiotensin system (RAS) has significant influences on heart and renal disease progression. Angiotensin converting enzyme (ACE) and angiotensin converting enzyme II (ACE2) are major peptidases of RAS components and play counteracting functions through angiotensin II (Ang II)/ATIR and angiotensin-(1-7) (Ang-(1-7))/Mas axis, respectively. METHODS: There were 360 uremic patients on regular hemodialysis (HD) treatment (inclusive of 119 HD patients with cardiovascular diseases (CVD) and 241 HD patients without CVD and 50 healthy subjects were enrolled in this study...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/29154445/long-term-cardiovascular-morbidity-and-mortality-in-patients-treated-for-differentiated-thyroid-cancer
#15
Nelli Pajamäki, Saara Metso, Tommi Hakala, Tapani Ebeling, Heini Huhtala, Essi Ryödi, Juhani Sand, Arja Jukkola-Vuorinen, Pirkko-Liisa Kellokumpu-Lehtinen, Pia Jaatinen
OBJECTIVE: Thyroid hormone suppression therapy has been widely used in the treatment of thyroid cancer, but concerns have been raised about the cardiovascular risks of this treatment. The objective of this study was to evaluate long-term cardiovascular morbidity and mortality in patients treated for differentiated thyroid cancer (DTC) and to assess the effect of TSH suppression and radioiodine (RAI) treatment on the cardiovascular outcome. DESIGN: Retrospective cohort study...
November 20, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29154226/short-term-exposures-to-pm2-5-and-cause-specific-mortality-of-cardiovascular-health-in-china
#16
Chen Chen, Pengfei Zhu, Li Lan, Lian Zhou, Ruicong Liu, Qinghua Sun, Jie Ban, Wentao Wang, Dandan Xu, Tiantian Li
BACKGROUND: Many multi-center epidemiological studies have robustly examined the acute health effects of exposure to low concentrations of fine particulate matter (PM2.5) on cardiovascular mortality in developed counties. However, data limitations have resulted in few related studies being conducted in developing counties with high levels of PM2.5 exposure. In recent years, people in China with a heavy cardiovascular disease burden have been exposed to particularly high levels of PM2...
November 16, 2017: Environmental Research
https://www.readbyqxmd.com/read/29153856/the-effect-of-viscous-soluble-fiber-on-blood-pressure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
K Khan, E Jovanovski, H V T Ho, A C R Marques, A Zurbau, S B Mejia, J L Sievenpiper, V Vuksan
AIMS: Dietary fiber intake, especially viscous soluble fiber, has been established as a means to reduce cardiometabolic risk factors. Whether this is true for blood pressure remains controversial. A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to investigate the effects of viscous soluble fiber supplementation on blood pressure and quantify the effect of individual fibers. DATA SYNTHESIS: MEDLINE, Embase, and Cochrane databases were searched...
October 7, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29153667/preeclampsia-and-later-cardiovascular-disease-what-do-national-guidelines-recommend
#18
Gitte Bro Schmidt, Martin Christensen, Ulla Breth Knudsen
Preeclamptic women have an increased risk of hypertension and cardiovascular disease (CVD) later in life. The aim was to compare the latest clinical recommendations on post-preeclamptic prevention of hypertension and CVD published by eight National Associations of Gynecologists and Obstetricians. Definitions of preeclampsia differ internationally. Recommendations on when, how and who to screen to reduce post-preeclamptic CVD risk also show substantial variation. The diverging preeclampsia definitions make CVD prevention strategies difficult to compare...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153607/serum-levels-of-25-hydroxyvitamin-d-predicts-infarct-volume-and-mortality-in-ischemic-stroke-patients
#19
Zhong Nie, Xiao-Chun Ji, Jian Wang, Hong-Xing Zhang
BACKGROUND: The aim of this study is to determine 25-hydroxyvitamin D [25(OH) D] levels in serum, and investigate their associations with cardiovascular disease (CVD) or all-cause mortality in a 1-year follow-up study in patients with first-ever ischemic stroke. METHODS: From November 2013 to October 2015, 387 consecutive patients with ischemic stroke admitted to our hospital were identified. Serum 25(OH) D levels were measured at admission. Infarct volume was measured using diffusion-weighted imaging (DWI)...
December 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29152661/apolipoprotein-status-in-type-2-diabetes-mellitus-and-its-complications-review
#20
Puhong Zhang, Jialin Gao, Chun Pu, Yao Zhang
Dyslipidaemia in type 2 diabetes mellitus (T2DM) is characterized by high plasma triglyceride concentrations, reduced high‑density lipoprotein concentrations and increased small density low‑density lipoprotein concentrations. Dyslipidaemia may lead to cardiovascular disease (CVD) and other complications. Apolipoproteins mainly comprise six species, apolipoprotein (apo)A, apoB, apoC, apoD, apoE and apoM, which are important components of plasma lipoproteins that carry lipids and stabilize the structure of lipoproteins...
October 19, 2017: Molecular Medicine Reports
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