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https://www.readbyqxmd.com/read/29345974/cognitive-effects-of-cancer-and-cancer-treatments
#1
Tim A Ahles, James C Root
As the population of cancer survivors has grown into the millions, there has been increasing emphasis on understanding how the late effects of treatment affect survivors' ability to return to work/school, their capacity to function and live independently, and their overall quality of life. This review focuses on cognitive change associated with cancer and cancer treatments. Research in this area has progressed from a pharmacotoxicology perspective to a view of the cognitive change as a complex interaction of aspects of the treatment, vulnerability factors that increase risk for posttreatment cognitive decline, cancer biology, and the biology of aging...
January 18, 2018: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/29345894/a-high-bandwidth-white-light-system-combining-a-micro-led-with-perovskite-quantum-dots-for-visible-light-communication
#2
Shiliang Mei, Xiaoyan Liu, Wanlu Zhang, Ran Liu, Lirong Zheng, Ruiqian Guo, Pengfei Tian
This work proposes a high-bandwidth white-light system consisting of a blue gallium nitride (GaN) micro-LED (μLED) exciting yellow-emitting CsPbBr1.8I1.2 perovskite quantum dots (YQDs) for high-speed real-time visible light communication (VLC). The packaged 80 μm × 80 μm blue-emitting μLED has a modulation bandwidth of ~160 MHz and a peak emission wavelength of ~445 nm. The achievable bandwidth of the white-light system is up to 85 MHz in the absence of filters and equalization technology. Meanwhile, the bandwidth of the YQDs as a color-converter is as high as 73 MHz with the blue GaN μLED as the pump source...
January 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29344472/status-epilepticus-as-an-unusual-manifestation-of-heat-stroke
#3
Won Gu Lee, So-Young Huh, Jin-Hyung Lee, Bong Goo Yoo, Meyung Kug Kim
Heat stroke (HS) is a medical emergency and life threatening condition, characterized by body temperature over 40°C. This can lead to dysfunction of multiple organs such as the heart, liver, kidneys, lungs, blood coagulation system, and central nervous system. Neurological complications include change in consciousness, cerebellar dysfunction, convulsions, aphasia, muscular weakness, and parkinsonism. Cerebellar syndrome is the most common neurological finding in HS. We report a case of HS presenting with status epilepticus, without any other neurological manifestations...
December 2017: Journal of Epilepsy Research
https://www.readbyqxmd.com/read/29344078/application-of-the-icf-based-norwegian-function-assessment-scale-to-employees-in-germany
#4
Sylvia Jankowiak, Uwe Rose, Norbert Kersten
Background: At the interface of the occupational setting and rehabilitation, normative values for functional ability are desirable and worthwhile. The Norwegian Function Assessment Scale (NFAS) is a 39 item self-report instrument based on the International Classification of Functioning, Disability and Health (ICF). As the questionnaire was not used in a working population, we aimed to obtain functional levels of employees in Germany as measured through the NFAS. Methods: The NFAS was included in the Study on Mental Health at Work (S-MGA) 2011/12, a representative German survey of employees aged 31 to 60 years...
2018: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/29342014/patterns-and-predictors-of-return-to-work-after-major-trauma-a-prospective-population-based-registry-study
#5
Alex Collie, Pamela M Simpson, Peter A Cameron, Shanthi Ameratunga, Jennie Ponsford, Ronan A Lyons, Sandra Braaf, Andrew Nunn, James E Harrison, Belinda J Gabbe
OBJECTIVE: To characterize patterns of engagement in work during the 4-year period after major traumatic injury, and to identify factors associated with those patterns. BACKGROUND: Employment is an important marker of functional recovery from injury. There are few population-based studies of long-term employment outcomes, and limited data on the patterns of return to work (RTW) after injury. METHODS: A population-based, prospective cohort study using the Victorian State Trauma Registry...
January 16, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29341859/an-indoor-air-quality-evaluation-in-a-residential-retrofit-project-using-spray-polyurethane-foam
#6
Shen Tian, Scott Ecoff, John Sebroski, Jason Miller, Harold Rickenbacker, Melissa Bilec
Understanding of indoor air quality (IAQ) during and after spray polyurethane foam (SPF) application is essential to protect the health of both workers and building occupants. Previous efforts such as field monitoring, micro-chamber/spray booth emission studies and fate/transport modeling have been conducted to understand the chemical exposure of SPF and guide risk mitigation strategies. However, each type of research has its limitation and can only reveal partial information on the relationship between SPF and IAQ...
January 17, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29341148/outcomes-after-prophylactic-gastrectomy-for-hereditary-diffuse-gastric-cancer
#7
R T van der Kaaij, J P van Kessel, J M van Dieren, P Snaebjornsson, O Balagué, F van Coevorden, L E van der Kolk, K Sikorska, A Cats, J W van Sandick
BACKGROUND: Patients with hereditary diffuse gastric cancer and a CDH1 mutation have a 60-80 per cent lifetime risk of developing diffuse gastric cancer. Total prophylactic gastrectomy eliminates this risk, but is associated with considerable morbidity. The effectiveness (removal of all gastric mucosa) and outcomes of this procedure were evaluated retrospectively. METHODS: All consecutive individuals undergoing a prophylactic gastrectomy for a CDH1 mutation or gastric signet ring cell foci at the authors' institute between 2005 and 2017 were included...
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29337172/organ-support-therapy-in-the-intensive-care-unit-and-return-to-work-in-out-of-hospital-cardiac-arrest-survivors-a-nationwide-cohort-study
#8
Signe Riddersholm, Kristian Kragholm, Rikke Nørmark Mortensen, Steen Moller Hansen, Mads Wissenberg, Freddy K Lippert, Christian Torp-Pedersen, Christian F Christiansen, Bodil Steen Rasmussen
AIM: With increased survival after out-of-hospital cardiac arrest (OHCA), impact of the post-resuscitation course has become important. Among 30-day OHCA survivors, we investigated associations between organ support therapy in the Intensive Care Unit (ICU) and return to work. METHODS: This Danish nationwide cohort-study included 30-day-OHCA-survivors who were employed prior to arrest. We linked OHCA data to information on in-hospital care and return to work. For patients admitted to an ICU and based on renal replacement therapy (RRT), cardiovascular support and mechanical ventilation, we assessed the prognostic value of organ support therapies in multivariable Cox regression models...
January 11, 2018: Resuscitation
https://www.readbyqxmd.com/read/29336206/working-in-global-health-a-planning-and-implementation-framework-for-international-electives
#9
Sarah T Thomas, Elizabeth T Thomas, Michelle McLean
PURPOSE: Propose a framework for planning and undertaking an international elective. METHODS: On returning from conducting maternal health and well-being research in several remote communities in India, two undergraduate medical students have reflected on and documented their experiences with the view to assisting other students (and their supervisors) considering undertaking an international elective. RESULTS: A framework for undertaking clinical or research electives in remote or rural communities is presented...
January 16, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29336020/return-to-driving-after-a-diagnosis-of-epilepsy-a-prospective-registry-study
#10
Ying Xu, Maree L Hackett, Nick Glozier, Armin Nikpour, Ernest Somerville, Andrew Bleasel, Carol Ireland, Craig S Anderson
OBJECTIVE: To determine the frequency and predictors of return to driving within 1 year after a diagnosis of epilepsy. METHODS: SEISMIC (the Sydney Epilepsy Incidence Study to Measure Illness Consequences) was a prospective, multicenter, community-wide study of people of all ages with newly diagnosed epilepsy in Sydney, Australia. Demographic, socioeconomic, and clinical characteristics and driving status were obtained as soon as possible after baseline registration with a diagnosis of epilepsy...
January 16, 2018: Epilepsia
https://www.readbyqxmd.com/read/29335011/generalized-estimation-of-the-ventilatory-distribution-from-the-multiple-breath-washout-a-bench-evaluation-study
#11
Gabriel Casulari Motta-Ribeiro, Frederico Caetano Jandre, Hermann Wrigge, Antonio Giannella-Neto
BACKGROUND: The multiple-breath washout (MBW) is able to provide information about the distribution of ventilation-to-volume (v/V) ratios in the lungs. However, the classical, all-parallel model may return skewed results due to the mixing effect of a common dead space. The aim of this work is to examine whether a novel mathematical model and algorithm is able to estimate v/V of a physical model, and to compare its results with those of the classical model. The novel model takes into account a dead space in series with the parallel ventilated compartments, allows for variable tidal volume (VT) and end-expiratory lung volume (EELV), and does not require a ideal step change of the inert gas concentration...
January 15, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29334887/bi-objective-integer-programming-for-rna-secondary-structure-prediction-with-pseudoknots
#12
Audrey Legendre, Eric Angel, Fariza Tahi
BACKGROUND: RNA structure prediction is an important field in bioinformatics, and numerous methods and tools have been proposed. Pseudoknots are specific motifs of RNA secondary structures that are difficult to predict. Almost all existing methods are based on a single model and return one solution, often missing the real structure. An alternative approach would be to combine different models and return a (small) set of solutions, maximizing its quality and diversity in order to increase the probability that it contains the real structure...
January 15, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29334790/cognitive-work-hardening-for-return-to-work-following-depression-an-intervention-study-le-r%C3%A3-entra%C3%A3-nement-cognitif-au-travail-pour-favoriser-le-retour-au-travail-%C3%A3-la-suite-d-une-d%C3%A3-pression-%C3%A3-tude-d-intervention
#13
Adeena Wisenthal, Terry Krupa, Bonnie H Kirsh, Rosemary Lysaght
BACKGROUND: Work absences due to depression are prevalent; however, few interventions exist to address the return-to-work challenges following a depressive episode. PURPOSE: This mixed-methods study aimed to (a) evaluate the effectiveness of cognitive work hardening in preparing people with depression to return to work and (b) identify key elements of the intervention. METHOD: A single group ( n = 21) pretest-posttest study design was used incorporating self-report measures (Work Ability Index, Multidimensional Assessment of Fatigue, Beck Depression Inventory II) with interviews at intervention completion and at 3-month follow-up...
January 1, 2018: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/29334117/the-relationship-between-office-type-and-job-satisfaction-testing-a-multiple-mediation-model-through-ease-of-interaction-and-well-being
#14
Tobias Otterbring, Jörg Pareigis, Erik Wästlund, Alexander Makrygiannis, Anton Lindström
Objectives This cross-sectional study investigated the associations between office type (cellular, shared-room, small open-plan, and medium-sized open-plan) and employees' ease of interaction with coworkers, subjective well-being, and job satisfaction. Methods A brief survey including measures of office type, ease of interaction with coworkers, subjective well-being, and job satisfaction was sent electronically to 1500 Swedish real-estate agents, 271 of whom returned usable surveys. The data were analyzed using a regression-based serial multiple mediation model (PROCESS Model 6), which tested whether the relationship between office type and job satisfaction would be mediated by ease of interaction and, in turn, subjective well-being...
January 15, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29330732/touching-the-spirit-re-enchanting-the-person-in-the-body
#15
Peggy L Determeyer, Julie E Kutac
In this essay, we argue that touch constitutes a sacred connection between the patient and practitioner. When touch is avoided or overlooked, the enigmatic inner workings of the body are ignored as those aspects of the body that can be quantified and ultimately controlled are emphasized. In utilizing touch as a fundamental way of opening up space for the sacred, the practitioner affirms the humanity for both the patient and herself. Only by returning to the senses can practitioners resist the dehumanizing effects of machinery and re-enchant the health-care profession in caring for persons they have sworn to serve...
January 12, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29326195/why-do-gps-leave-direct-patient-care-and-what-might-help-to-retain-them-a-qualitative-study-of-gps-in-south-west-england
#16
Anna Sansom, Rohini Terry, Emily Fletcher, Chris Salisbury, Linda Long, Suzanne H Richards, Alex Aylward, Jo Welsman, Laura Sims, John L Campbell, Sarah G Dean
OBJECTIVE: To identify factors influencing general practitioners' (GPs') decisions about whether or not to remain in direct patient care in general practice and what might help to retain them in that role. DESIGN: Qualitative, in-depth, individual interviews exploring factors related to GPs leaving, remaining in and returning to direct patient care. SETTING: South West England, UK. PARTICIPANTS: 41 GPs: 7 retired; 8 intending to take early retirement; 11 who were on or intending to take a career break; 9 aged under 50 years who had left or were intending to leave direct patient care and 6 who were not intending to leave or to take a career break...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29326181/what-are-the-sources-of-stress-and-distress-for-general-practitioners-working-in-england-a-qualitative-study
#17
Ruth Riley, Johanna Spiers, Marta Buszewicz, Anna Kathryn Taylor, Gail Thornton, Carolyn Anne Chew-Graham
OBJECTIVES: This paper reports the sources of stress and distress experienced by general practitioners (GP) as part of a wider study exploring the barriers and facilitators to help-seeking for mental illness and burnout among this medical population. DESIGN: Qualitative study using in-depth interviews with 47 GP participants. The interviews were audio-recorded, transcribed, anonymised and imported into NVivo V.11 to facilitate data management. Data were analysed using a thematic analysis employing the constant comparative method...
January 11, 2018: BMJ Open
https://www.readbyqxmd.com/read/29326145/return-to-work-and-participation-in-society-after-out-of-hospital-cardiac-arrest
#18
Gisela Lilja, Niklas Nielsen, John Bro-Jeppesen, Hannah Dunford, Hans Friberg, Caisa Hofgren, Janneke Horn, Angelo Insorsi, Jesper Kjaergaard, Fredrik Nilsson, Paolo Pelosi, Tineke Winters, Matt P Wise, Tobias Cronberg
BACKGROUND: The aim of this study was to describe out-of-hospital cardiac arrest (OHCA) survivors' ability to participate in activities of everyday life and society, including return to work. The specific aim was to evaluate potential effects of cognitive impairment. METHODS AND RESULTS: Two hundred eighty-seven OHCA survivors included in the TTM trial (Target Temperature Management) and 119 matched control patients with ST-segment-elevation myocardial infarction participated in a follow-up 180 days post-event that included assessments of participation, return to work, emotional problems, and cognitive impairment...
January 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29319352/dual-antegrade-intramedullary-headless-screw-fixation-for-treatment-of-unstable-proximal-phalanx-fractures
#19
Michael P Gaspar, Shiv D Gandhi, Randall W Culp, Patrick M Kane
BACKGROUND: Although intramedullary headless screw (IMHS) fixation is a promising minimally invasive surgical treatment option for unstable proximal phalanx fractures, a single IMHS may provide inadequate fixation for certain fracture patterns. The purpose of this study was to evaluate the short-term clinical outcomes in a pilot series of patients with proximal phalanx fractures treated with dual antegrade IMHS fixation. METHODS: We performed a retrospective chart review of proximal phalanx fractures treated with dual antegrade IMHS fixation with a minimum 1 year of follow-up...
January 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29318360/a-novel-percutaneous-achievement-and-maintenance-of-reduction-and-screw-fixation-for-acute-displaced-scaphoid-fractures-minimum-two-year-follow-up
#20
Yadong Yu, Haibin Cui, Xiaoliang Yang, Xiaofei Yu, Yanbin Bai
PURPOSE: The purpose of this study was to introduce a novel method of percutaneous achievement and maintenance of reduction for acute displaced scaphoid fractures and evaluate the feasibility of this method in treating acute displaced scaphoid fractures as well as explore its indications. METHODS: From February 2012 to March 2014, 15 patients with acute displaced scaphoid fractures were treated with our technique. Two Kirschner wires were used to achieve and maintain the reduction of the scaphoid fractures throughout the entire process of the traditional percutaneous screw fixation process...
January 10, 2018: International Orthopaedics
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