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acquired brain injury

Thomas Maribo, Asger R Pedersen, Jim Jensen, Jørgen F Nielsen
BACKGROUND: Assessing primary rehabilitation needs in patients with acquired brain injury is a challenge due to case complexity and the heterogeneity of symptoms after brain injury. The Rehabilitation Complexity Scale-Extended (RCS-E) is an instrument used in assessment of rehabilitation complexity in patients with severe brain injury. The aim of the present study was to translate and test the face validity of the RCS-E as a referral tool for primary rehabilitation. Face validity was tested in a sample of patients with acquired brain injury...
October 21, 2016: BMC Neurology
Luiz Fernando Almeida Silva, Tobias Engel, Cristina R Reschke, Ronan M Conroy, Elena Langa, David C Henshall
Animal models of status epilepticus are important tools to understand the pathogenesis of epileptic brain injury and evaluate potential seizure-suppressive, neuroprotective, and antiepileptogenic treatments. Focal elicitation of status epilepticus by intraamygdala kainic acid in mice produces unilateral hippocampal damage and the emergence of spontaneous recurrent seizures after a short latent period. The model has been characterized in C57BL/6, BALB/c, and SJL mice where strain-specific differences were found in the extent of hippocampal damage...
October 13, 2016: Epilepsy & Behavior: E&B
Andreas Bender, Christine Adrion, Luzia Fischer, Martin Huber, Kerstin Jawny, Andreas Straube, Ulrich Mansmann
BACKGROUND: Patients with acquired brain injury who have been discharged from inpatient neurological rehabilitation often continue to suffer from limited independence, participation, and quality of life. Participation-focused outpatient treatment (in German: teilhabeorientierte ambulan. METHODS: In a randomized, controlled trial, 53 patients who had sustained an acquired brain injury approximately four years earlier were allotted to two different sequences of treatment (26 TEAM/control, 27 control/TEAM)...
September 23, 2016: Deutsches Ärzteblatt International
Audrey McKinlay, Mark Linden, Roberta DePompei, Catherine Aaro Jonsson, Vicki Anderson, Lucia Braga, Enrico Castelli, Peter de Koning, Carol A Hawley, Eric Hermans, Ingela Kristiansen, Alison Madden, Peter Rumney, Ron Savage, Beth Wicks
BACKGROUND: Providing appropriate rehabilitation services for Acquired Brain Injury (ABI) in childhood presents a number of challenges for caregivers, health and education professionals and the young person as they develop. PRIMARY OBJECTIVE: To record the challenges and possible creative solutions generated by an international group of professionals to address the needs of children with ABI. Review of information: Recommendations were generated from children's special interest group meetings of the International Brain Injury Association (Turin, Italy, 2001; Stockholm, Sweden, 2003; Melbourne, Australia, 2005; Lisbon, Portugal, 2008) and through meetings of the International Paediatric Brain Injury Society (IPBIS), formed in 2009...
October 14, 2016: Brain Injury: [BI]
Volker Ressel, Ruth O'Gorman Tuura, Ianina Scheer, Hubertus J A van Hedel
BACKGROUND: Rehabilitation in children with acquired brain injury is a challenging endeavour. There is a large variability in motor recovery between patients, and a need to optimize therapies by exploiting cerebral plasticity and recovery mechanisms. This retrospective study aims to identify tract-based markers that could serve as predictors of functional outcome following rehabilitation. METHODS: Twenty-nine children with traumatic brain injury (n = 14) or stroke (n = 15) underwent a 3 T Magnetic Resonance Imaging (MRI) measurement, including Diffusion Tensor Imaging (DTI) between admission to the Hospital and onset of rehabilitation therapy at the Rehabilitation Centre...
October 12, 2016: Brain Imaging and Behavior
David Salisbury, Simon J Driver, Megan Reynolds, Monica Bennett, Laura B Petrey, Anne Marie Warren
OBJECTIVE: To investigate trends of hospital-based health care utilization after admission to a Level 1 trauma center following acute traumatic brain injury (TBI). DESIGN: Retrospective review. SETTING: Large urban trauma hospital and a hospital council data registry consisting of 88 member institutions (>150 hospitals) covering 15,000 square miles. PARTICIPANTS: All patients admitted to a Level I trauma center between January 2006 - June 2014 who experienced an acute TBI based on ICD-9 coding...
October 6, 2016: Archives of Physical Medicine and Rehabilitation
Grahame Simpson, Francis Yuen
This special issue of the Journal of Social Work in Disability and Rehabilitation, Contemporary Perspectives on Social Work in Acquired Brain Injury, has been initiated and coordinated by the International Network of Social Workers in Acquired Brain Injury (INSWABI). In introducing the issue, some space will be allocated for providing definitions of traumatic brain injury (TBI) and acquired brain injury (ABI); outlining the epidemiology and global costs; and detailing the impairments and psychosocial impacts for both the person sustaining the injury and his/her family...
August 11, 2016: Journal of Social Work in Disability & Rehabilitation
Iris Yuwen Zhou, Taylor L Fuss, Takahiro Igarashi, Weiping Jiang, Xin Zhou, Leo L Cheng, Phillip Zhe Sun
Chemical exchange saturation transfer (CEST) provides sensitive MR contrast for probing dilute compounds via exchangeable protons, serving as an emerging molecular imaging methodology. CEST Z-spectrum is often acquired by sweeping radiofrequency saturation around bulk water resonance, offset by offset, to detect CEST effects at characteristic chemical shift offsets, which requires prolonged acquisition time. Herein, combining high-resolution magic angle spinning (HRMAS) with concurrent application of gradient and RF saturation to achieve fast Z-spectral acquisition, we demonstrated the feasibility of fast quantitative HRMAS CEST Z-spectroscopy...
October 6, 2016: Analytical Chemistry
Katherine Osborne-Crowley, Skye McDonald
Acquired social disinhibition refers to a debilitating behavioural syndrome commonly reported after a severe traumatic brain injury (TBI) and is characterized by inappropriate social behaviour, often described as immaturity and insensitivity towards others. These behaviours can have enduring effects on the social capability of the individual and their relationships with others. However, research into socially disinhibited behaviour after TBI has been thwarted by a lack of consensus in the literature on definition and measurement...
September 30, 2016: Journal of Neuropsychology
Rita Formisano, Eva Azicnuda, Maryam Khan Sefid, Mauro Zampolini, Federico Scarponi, Renato Avesani
Establish the best time to start rehabilitation by means of scientific evidence. Observational study in patients with a diagnosis of Severe Brain Injury who received intensive inpatient rehabilitation after acute care. 1470 subjects enrolled: 651 with Traumatic Brain Injury (TBI) and 819 with Non-TBI. Male gender was prevalent in the population study, but sex distribution was not different among groups, with a prevalence of male gender in both populations. This project involved 29 rehabilitation facilities for Severe ABI...
October 1, 2016: Neurological Sciences
Jeremy Kawahara, Colin J Brown, Steven P Miller, Brian G Booth, Vann Chau, Ruth E Grunau, Jill G Zwicker, Ghassan Hamarneh
We propose BrainNetCNN, a convolutional neural network (CNN) framework to predict clinical neurodevelopmental outcomes from brain networks. In contrast to the spatially local convolutions done in traditional image-based CNNs, our BrainNetCNN is composed of novel edge-to-edge, edge-to-node and node-to-graph convolutional filters that leverage the topological locality of structural brain networks. We apply the BrainNetCNN framework to predict cognitive and motor developmental outcome scores from structural brain networks of infants born preterm...
September 28, 2016: NeuroImage
J Keshav Kumar, Akila Sadasivan
OBJECTIVE: This is an invited paper for a special issue with the objective to provide information on neuropsychology in India. METHOD: Information was gathered from a literature search and personal communication with professionals working in the field of neuropsychology. RESULTS: Neuropsychology as a specialization started in India approximately 40 years ago. The early years witnessed the use of Western tools for assessing patients with organic brain damage...
November 2016: Clinical Neuropsychologist
Gordon Lyons, Tania De Bortoli, Michael Arthur-Kelly
PURPOSE: This paper explains and demonstrates the pilot application of Triangulated Proxy Reporting (TPR); a practical technique for enhancing communication around people who have severe cognitive impairment (SCI). METHODS AND RESULTS: An introduction explains SCI and how this impacts on communication; and consequently on quality of care and quality of life. This is followed by an explanation of TPR and its origins in triangulation research techniques. An illustrative vignette explicates its utility and value in a group home for a resident with profound multiple disabilities...
August 16, 2016: Disability and Rehabilitation
Therese M O'Neil-Pirozzi, Henry Hsu
PRIMARY OBJECTIVE: The purpose of this pilot study was to explore feasibility and effects of participation in a computerized cognitive fitness exercise program by a group of adults with chronic moderate-to-severe cognitive impairments following an acquired brain injury (ABI). RESEARCH DESIGN: This study used a mixed methods design with a convenience sample of individuals forming two groups (+/- exercise). METHODS AND PROCEDURES: Following neurocognitive and satisfaction with life pre-testing of 14 participants, seven were enrolled in a 5-month, 5-days a week computerized cognitive exercise program...
September 28, 2016: Brain Injury: [BI]
Marieke Chamberon, Corinne Catale, Bernadette Kerrouche, Hanna Touré, Anne Laurent-Vannier, Dominique Brugel, Emmanuelle Pineau-Chardon, Aude Mariller, Ouarda Benkhaled, Virginie Kieffer, Miriam Beauchamp, Mathilde Chevignard
OBJECTIVE: Childhood acquired brain injury (ABI) is the leading cause of acquired disability in childhood, with significant consequences on independence, academic achievement and participation. The "Child and Adolescent Scale of Participation" (CASP; Bedell 2004) has been specifically developed to assess participation following childhood ABI. The aim of this study was to examine the psychometric properties of the French version of the Child and Adolescent Scale of Participation. MATERIAL/PATIENTS AND METHODS: Cross-sectional, monocentric study...
September 2016: Annals of Physical and Rehabilitation Medicine
Anne-Lyse Jaquot, Emmanuel Vega, Xavier Molders, Walter Daveluy, François Kopciuch, Anne Benoit, Etienne Allart
OBJECTIVE: Management of tracheotomy is a key point of the coma arousal phase. Tracheal lesions can interfere with the decannulation of the patient. The objectives of our study were to determine the incidence of post-tracheotomy tracheal lesions in patients with brain injury, identify their associated factors and to specify their impact on rehabilitation. MATERIAL/PATIENTS AND METHODS: We retrospectively included brain-injured patients hospitalized in the neurosurgical intensive care unit then in the coma arousal unit of the Lille university hospital between January 2012 and December 2014...
September 2016: Annals of Physical and Rehabilitation Medicine
Mathilde Chevignard, Leila Francillette, Hanna Toure, Dominique Brugel, Philippe Meyer, Anne Laurent Vannier, Marion Opatowski, Laurence Watier
OBJECTIVE: Childhood traumatic brain injury (TBI) is the first cause of death and acquired disability and it represents a major public health issue. Childhood severe TBI can lead to motor, cognitive, behavioural and social cognition deficits, which have consequences on academic achievement, social integration, participation and quality of life. Consequences may only appear after a delay, when the skills are supposed to be fully developed. The aim of this study was to prospectively assess academic outcome, health-related quality of life (HRQoL), amount of ongoing care and participation, following childhood severe traumatic brain injury (TBI) over 7-8years post-injury, in comparison with a matched uninjured control group...
September 2016: Annals of Physical and Rehabilitation Medicine
Mathilde Chevignard, Leila Francillette, Hanna Toure, Dominique Brugel, Philippe Meyer, Anne Laurent Vannier, Marion Opatowski, Laurence Watier
OBJECTIVE: Childhood traumatic brain injury (TBI) is a leading cause of death and lifelong acquired disability. The aim of this study was to prospectively study intellectual ability following childhood severe TBI over 7-8years post-injury, and factors influencing outcome and change over time. MATERIAL/PATIENTS AND METHODS: Children (0-15years) consecutively admitted in a single trauma center for severe non-inflicted TBI over a 3-year period were included in a prospective longitudinal study...
September 2016: Annals of Physical and Rehabilitation Medicine
D L Dickstein, M Y Pullman, C Fernandez, J A Short, L Kostakoglu, K Knesaurek, L Soleimani, B D Jordan, W A Gordon, K Dams-O'Connor, B N Delman, E Wong, C Y Tang, S T DeKosky, J R Stone, R C Cantu, M Sano, P R Hof, S Gandy
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disorder most commonly associated with repetitive traumatic brain injury (TBI) and characterized by the presence of neurofibrillary tangles of tau protein, known as a tauopathy. Currently, the diagnosis of CTE can only be definitively established postmortem. However, a new positron emission tomography (PET) ligand, [(18)F]T807/AV1451, may provide the antemortem detection of tau aggregates, and thus various tauopathies, including CTE. Our goal was to examine [(18)F]T807/AV1451 retention in athletes with neuropsychiatric symptoms associated with a history of multiple concussions...
2016: Translational Psychiatry
Mithra B Maneyapanda, Zachary McCormick, Christina M Marciniak, Christopher D Reger
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
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