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acquired brain injury

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https://www.readbyqxmd.com/read/29345501/-it-s-nothing-you-could-ever-prepare-anyone-for-the-experiences-of-young-people-and-their-families-following-parental-stroke
#1
Clare Coppock, Scott Ferguson, Anna Green, David Winter
AIMS: This study sought to explore the experiences of young people (aged 8-16) and their families following parental acquired brain injury (ABI), with the aim of developing an understanding of the ways in which members of a family make sense of events post-injury, and to consider the implications of different perspectives on adjustment and coping. DESIGN: The study applied a qualitative approach using a thematic analysis methodology. PROCEDURE: Individual semi-structured interviews were conducted with 10 individuals from three families affected by parental stroke...
January 18, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29334802/youth-and-young-adults-with-acquired-brain-injury-transition-towards-work-related-roles-a-qualitative-study
#2
Alicia Paniccia, Heather Colquhoun, Bonnie Kirsh, Sally Lindsay
PURPOSE: The purpose of this research was to explore the experiences of youth and young adults with acquired brain injury as they transition towards work-related roles. Little is known about employment experiences among this age group. Understanding their perspectives can inform programs and clinical practice. MATERIALS AND METHODS: A descriptive qualitative design, including semi-structured interviews with 14 participants (8 females; 6 males) was used. Interviews were transcribed verbatim and analyzed using an open-coding, thematic approach...
January 15, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29321682/intermittent-metabolic-switching-neuroplasticity-and-brain-health
#3
REVIEW
Mark P Mattson, Keelin Moehl, Nathaniel Ghena, Maggie Schmaedick, Aiwu Cheng
During evolution, individuals whose brains and bodies functioned well in a fasted state were successful in acquiring food, enabling their survival and reproduction. With fasting and extended exercise, liver glycogen stores are depleted and ketones are produced from adipose-cell-derived fatty acids. This metabolic switch in cellular fuel source is accompanied by cellular and molecular adaptations of neural networks in the brain that enhance their functionality and bolster their resistance to stress, injury and disease...
January 11, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29305661/techniques-of-cognitive-rehabilitation-in-patients-with-disorders-of-consciousness-a-systematic-review
#4
Elena La Gattuta, Francesco Corallo, Viviana Lo Buono, Simona De Salvo, Fabrizia Caminiti, Carmela Rifici, Antonella Alagna, Francesca Arcadi, Alessia Bramanti, Silvia Marino
Acquired brain injury can produce severe impairments of alertness, cognition, behavior, and, sometimes, an impairment of consciousness. Several studies defined the criteria to distinguish the different level of disorders of consciousness (DOC) and many tools to evaluate awareness, alertness, and response to stimuli were created. The aim of this review is to assess the advanced research of rehabilitative protocols and which rehabilitative techniques are used in the care of DOC patients.
January 5, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29300227/families-needs-of-patients-with-acquired-brain-injury-acute-phase-and-rehabilitation
#5
Véronique de Goumoëns, Amélia Didier, Cédric Mabire, Maya Shaha, Karin Diserens
PURPOSE: The aim of this study was to identify and compare the needs of families of patients with acquired brain injury (ABI) in acute care and rehabilitation settings. DESIGN: A descriptive exploratory study was conducted. METHODS: Data were collected in the acute care setting and in the rehabilitation setting during meetings with families (n = 54) of patients with ABI using the Family Needs Questionnaire. FINDINGS: In both settings, families identified obtaining information about ABI or the patients' health as the most important need, followed by support from health professionals...
January 3, 2018: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29296629/alterations-in-neurovascular-coupling-following-acute-traumatic-brain-injury
#6
Hyounguk Jang, Stanley Huang, Daniel X Hammer, Lin Wang, Harmain Rafi, Meijun Ye, Cristin G Welle, Jonathan A N Fisher
Following acute traumatic brain injury (TBI), timely transport to a hospital can significantly improve the prognosis for recovery. There is, however, a dearth of quantitative biomarkers for brain injury that can be rapidly acquired and interpreted in active, field environments in which TBIs are frequently incurred. We explored potential functional indicators for TBI that can be noninvasively obtained through portable detection modalities, namely optical and electrophysiological approaches. By combining diffuse correlation spectroscopy with colocalized electrophysiological measurements in a mouse model of TBI, we observed concomitant alterations in sensory-evoked cerebral blood flow (CBF) and electrical potentials following controlled cortical impact...
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/29291381/custom-fabrication-of-a-3-dimensionally-printed-helmet-for-improved-socialization-and-subjective-self-assessment-in-a-case-of-acquired-cranial-defect-a-case-presentation
#7
Cesar Colasante, Zachary Sanford, Nileyma Castro, Matthew Bartels
Traumatic injury and subsequent residual cosmetic deformity are subject of intense scrutiny for their effects on objective health measures assessing patient morbidity and mortality. Although these remain principal concerns of all members of the treatment team, of less immediate yet lasting importance to the patient are the social costs of such disfigurement. Subjective feelings of unease and embarrassment can hinder social reintegration and encourage deteriorating psychosocial health. The following presents a case of one such individual who sustained traumatic brain injury and associated pneumocephalus and osteomyelitis requiring surgical debridement with bifrontal craniectomy and lobotomy...
December 29, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29283024/assessment-of-executive-functions-in-children-and-adolescents-with-acquired-brain-injury-abi-using-a-novel-complex-multi-tasking-computerised-task-the-jansari-assessment-of-executive-functions-for-children-jef-c%C3%A2
#8
Yafit Gilboa, Ashok Jansari, Bernadette Kerrouche, Emel Uçak, Anne Tiberghien, Ouarda Benkhaled, Delphine Aligon, Aude Mariller, Valentine Verdier, Amaia Mintegui, Geneviève Abada, Céline Canizares, Andrew Goldstein, Mathilde Chevignard
OBJECTIVES: The Jansari assessment of Executive Functions for Children (JEF-C©) is a new non-immersive computerised assessment of executive functions. The objectives of the study were to test the feasibility and validity of JEF-C© in children and adolescents with acquired brain injury (ABI). METHODS: Twenty-nine patients with ABI aged 10-18 years and 30 age-and gender-matched controls were tested. Participants performed JEF-C©, Wechsler Abbreviated Scale of Intelligence (WASI) and the Behavioural Assessment of the Dysexecutive Syndrome for Children (BADS-C), while parents completed the Behaviour Rating Inventory of Executive Function (BRIEF) questionnaire...
December 28, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/29275788/a-systematic-review-of-anxiety-interventions-in-stroke-and-acquired-brain-injury-efficacy-and-trial-design
#9
Ho-Yan Yvonne Chun, Richard Newman, William N Whiteley, Martin Dennis, Gillian E Mead, Alan J Carson
OBJECTIVE: There is little randomized controlled trial (RCT) evidence to guide treatment for anxiety after stroke. We systematically reviewed RCTs of anxiety interventions in acquired brain injury (ABI) conditions including stroke and traumatic brain injury (TBI) in order to summarize efficacy and key aspects of trial design to help guide future RCTs. METHODS: We searched the Cochrane trial register, Medline, Embase, PsychInfo and CINAHL systematically up to August 2017...
January 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29260837/the-challenges-of-describing-rehabilitation-services-a-discussion-paper
#10
Cecilie Røe, Marit Kirkevold, Nada Andelic, Helene L Soberg, Unni Sveen, Erik Bautz-Holter, Reidun Jahnsen, Marleen R van Walsem, Line Kildal Bragstad, Ellen Gabrielsen Hjelle, Gunvor Klevberg, Per Oretorp, Andreas Habberstad, Jon Hagfors, Randi Væhle, Grace Engen, Christoph Gutenbrunner
To apply the Classification of Service Organization in Rehabilitation (ICSO-R) classification of services to different target groups, include the user perspective, identify missing categories, and propose standardized descriptors for the categories from a Norwegian perspective. Expert-based consensus conferences with user involvement. Health professionals, stakeholders and users. Participants were divided into 5 panels, which applied the ICSO-R to describe the habilitation and rehabilitation services provided to children with cerebral palsy and people with Huntington's disease, acquired brain injuries (traumatic brain injuries and stroke) and painful musculoskeletal conditions...
December 20, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29251113/microarray-expression-profile-of-lncrnas-and-mrnas-in-rats-with-traumatic-brain-injury-after-a2b5-cell-transplantation
#11
Qiang Lyu, Zi-Bin Zhang, Song-Jun Fu, Liu-Lin Xiong, Jing Liu, Ting-Hua Wang
Traumatic brain injury (TBI) may cause neurological damage, but an effective therapy and the associated mechanisms of action have not yet been elucidated. A TBI model was established using the modified Feeney method. A2B5+ cells, an oligodendroglial progenitor, were acquired from induced pluripotent stem cells (iPSCs) by mouse embryonic fibroblasts and were transplanted into the injured site. The neurological severity score (NSS) was recorded on 3 d, 7 d, 11 d, 15 d, and 19 d. Seven days after transplantation, oligodendrocytes 2 (Olig2) and myelin basic protein (MBP) were detected by immunohistochemistry (IHC) and Western blot (WB), and long noncoding RNAs (lncRNAs) and messenger RNAs (mRNAs) were screened by microarray technology...
October 2017: Cell Transplantation
https://www.readbyqxmd.com/read/29247482/commonalities-in-epileptogenic-processes-from-different-acute-brain-insults-do-they-translate
#12
REVIEW
Pavel Klein, Raymond Dingledine, Eleonora Aronica, Christophe Bernard, Ingmar Blümcke, Detlev Boison, Martin J Brodie, Amy R Brooks-Kayal, Jerome Engel, Patrick A Forcelli, Lawrence J Hirsch, Rafal M Kaminski, Henrik Klitgaard, Katja Kobow, Daniel H Lowenstein, Phillip L Pearl, Asla Pitkänen, Noora Puhakka, Michael A Rogawski, Dieter Schmidt, Matti Sillanpää, Robert S Sloviter, Christian Steinhäuser, Annamaria Vezzani, Matthew C Walker, Wolfgang Löscher
The most common forms of acquired epilepsies arise following acute brain insults such as traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for only 60%-70% of patients and remains symptomatic despite decades of effort to develop epilepsy prevention therapies. Recent preclinical efforts are focused on likely primary drivers of epileptogenesis, namely inflammation, neuron loss, plasticity, and circuit reorganization. This review suggests a path to identify neuronal and molecular targets for clinical testing of specific hypotheses about epileptogenesis and its prevention or modification...
December 15, 2017: Epilepsia
https://www.readbyqxmd.com/read/29244046/humor-a-rehabilitative-tool-in-the-post-intensive-care-of-young-adults-with-acquired-brain-injury
#13
Kate O'Reilly
PURPOSE: The aim of the study was to describe how paid carers use humor in providing compassionate post-intensive rehabilitation care to young adults with acquired brain injury (ABI) who are unable to perform or direct their own care. DESIGN: This is a qualitative study underpinned by symbolic interactionism. METHODS: Paid carers in a residential aged care facility were interviewed. Interview data were analyzed using grounded theory methods of coding, comparative analysis, memoing, and theoretical sampling...
July 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29215914/feasibility-and-effectiveness-of-a-parenting-programme-for-mexican-parents-of-children-with-acquired-brain-injury-case-report
#14
Clara Chavez-Arana, Cathy Catroppa, Guillermina Yáñez Téllez, Celia Godfrey, Belén Prieto-Corona, Miguel A de León, Antonio García, Vicki Anderson
BACKGROUND: Acquired brain injury (ABI) during childhood typically causes behaviour problems in the child and high levels of stress in the family. OBJECTIVES: (1) To investigate the feasibility and effectiveness of a parenting programme to: improve behaviour and self-regulation (SR) in Mexican children with ABI, enhance parenting skills, and decrease parental stress in parents of children with ABI; (2) to explore the impact of parent SR on child. METHODS: Case study design with four participants post-ABI, aged 7-12 years, recruited in Mexico City...
December 7, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29214386/improvement-rate-of-patients-with-severe-brain-injury-during-post-acute-intensive-rehabilitation
#15
Rita Formisano, Marianna Contrada, Marta Aloisi, Maria Gabriella Buzzi, Paola Cicinelli, Cecilia Della Vedova, Letizia Laurenza, Maria Matteis, Francesca Spanedda, Vincenzo Vinicola, Marco Iosa
Patients with severe acquired brain injury (SABI) may evolve towards different outcomes. The primary aim was to evaluate the clinical evolution of a large population of patients with SABI admitted to post-acute rehabilitation from 2001 to 2016, diagnosed with severe brain injury (GCS ≤ 8) in the acute phase and a coma duration of at least 24 h. The possible changes between the admission time to a post-acute rehabilitation hospital and the discharge time were measured by means of Glasgow Outcome Scale (GOS), Level of Cognitive Functioning (LCF), and Disability Rating Scale (DRS)...
December 6, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29206059/efficacy-of-an-intervention-programme-for-rehabilitation-of-awareness-of-deficit-after-acquired-brain-injury-a-pilot-study
#16
Dolores Villalobos, Álvaro Bilbao, Alfonso Espejo, Javier García-Pacios
BACKGROUND: Impaired Awareness of Deficit (AD) is a frequent symptom after suffering acquired brain injury (ABI) that severely influences patients' daily lives. PRIMARY OBJECTIVE: Pilot study to assess the effectiveness of a structured intervention programme which was developed from a biopsychosocial approach, and relied on common therapeutic strategies of proven effectiveness. METHODS: We assessed the effectiveness of our intervention on a sample of 60 patients with ABI, 30 of whom received the specific AD intervention programme, while the other 30 followed an equivalent rehabilitation approach where they received no specific intervention on AD...
December 5, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29194177/efficacy-of-a-micro-prompting-technology-in-reducing-support-needed-by-people-with-severe-acquired-brain-injury-in-activities-of-daily-living-a-randomized-control-trial
#17
Brian OʼNeill, Catherine Best, Lauren OʼNeill, Sara D S Ramos, Alex Gillespie
OBJECTIVE: To evaluate the effectiveness of an automated interactive prompting technology in supporting the morning routine of persons with acquired brain injury. The morning routine included maintaining personal hygiene and dressing. SETTING: An inpatient neurorehabilitation hospital. PARTICIPANTS: Persons with acquired brain injury who required prompting when following their morning routine (n = 24), but were not limited by physical disability or dysphasia, took part in the study...
November 29, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/29193309/converging-early-responses-to-brain-injury-pave-the-road-to-epileptogenesis
#18
REVIEW
Eric J Neuberger, Akshay Gupta, Deepak Subramanian, Akshata A Korgaonkar, Vijayalakshmi Santhakumar
Epilepsy, characterized by recurrent seizures and abnormal electrical activity in the brain, is one of the most prevalent brain disorders. Over two million people in the United States have been diagnosed with epilepsy and 3% of the general population will be diagnosed with it at some point in their lives. While most developmental epilepsies occur due to genetic predisposition, a class of "acquired" epilepsies results from a variety of brain insults. A leading etiological factor for epilepsy that is currently on the rise is traumatic brain injury (TBI), which accounts for up to 20% of all symptomatic epilepsies...
November 29, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29192337/pediatric-emergency-department-visits-for-pedestrian-and-bicyclist-injuries-in-the-us
#19
Katherine Wheeler-Martin, Stephen J Mooney, David C Lee, Andrew Rundle, Charles DiMaggio
BACKGROUND: Despite reductions in youth pedestrian and bicyclist deaths over the past two decades, these injuries remain a substantial cause of morbidity and mortality for children and adolescents. There is a need for additional information on non-fatal pediatric pedestrian injuries and the role of traumatic brain injury (TBI), a leading cause of acquired disability. METHODS: Using a multi-year national sample of emergency department (ED) records, we estimated annual motorized-vehicle related pediatric pedestrian and bicyclist (i...
December 1, 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/29191480/preterm-birth-leads-to-hyper-reactive-cognitive-control-processing-and-poor-white-matter-organization-in-adulthood
#20
Alexander Olsen, Emily L Dennis, Kari Anne I Evensen, Ingrid Marie Husby Hollund, Gro C C Løhaugen, Paul M Thompson, Ann-Mari Brubakk, Live Eikenes, Asta K Håberg
Individuals born preterm with very low birth weight (VLBW; birth weight ≤ 1500 g) are at high risk for perinatal brain injuries and deviant brain development, leading to increased chances of later cognitive, emotional, and behavioral problems. Here we investigated the neuronal underpinnings of both reactive and proactive cognitive control processes in adults with VLBW. We included 32 adults born preterm with VLBW (before 37th week of gestation) and 32 term-born controls (birth weight ≥10th percentile for gestational age) between 22 and 24 years of age that have been followed prospectively since birth...
November 27, 2017: NeuroImage
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