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acquired brain injury

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https://www.readbyqxmd.com/read/29787864/the-neonatal-brain-in-critical-congenital-heart-disease-insights-and-future-directions
#1
REVIEW
Shabnam Peyvandi, Beatrice Latal, Steven P Miller, Patrick S McQuillen
Neurodevelopmental outcomes are impaired in survivors of critical congenital heart disease (CHD) in several developmental domains including motor, cognitive and sensory outcomes. These deficits can extend into the adolescent and early adulthood years. The cause of these neurodevelopmental impairments is multi-factorial and includes patient specific risk factors, cardiac anatomy and physiology as well as brain changes seen on MRI. Advances in imaging techniques have identified delayed brain development in the neonate with critical CHD as well as acquired brain injury...
May 19, 2018: NeuroImage
https://www.readbyqxmd.com/read/29786464/what-can-we-learn-from-diffusion-tensor-imaging-from-a-large-traumatic-brain-injury-cohort-white-matter-integrity-and-its-relationship-with-outcome
#2
Ana M Castaño-Leon, Marta Cicuendez, Blanca Navarro, Pablo M Munarriz, Santiago Cepeda, Igor Paredes, Amaya Hilario, Ana Ramos, Pedro Antonio Gomez, Alfonso Lagares
Traumatic axonal injury (TAI) contributes significantly to mortality and morbidity after traumatic brain injury (TBI) but its identification is still a diagnostic challenge because of the limitations of conventional imaging techniques to characterized it. Diffusion tensor imaging (DTI) can indirectly identify areas of damaged white matter (WM) integrity by detecting water molecules diffusion alterations. Therefore, DTI may improve detection and description of TAI lesions after TBI. We have obtained DTI data from 217 patients with moderate to severe TBI acquired at median 19 days after TBI were and patient DTI metrics were compared with data obtained from 58 age-matched healthy controls...
May 22, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29786461/gender-and-diagnostic-impact-on-everyday-technology-use-a-differential-item-functioning-dif-analysis-of-the-everyday-technology-use-questionnaire-etuq
#3
Anders Kottorp, Camilla Malinowsky, Maria Larsson-Lund, Louise Nygård
BACKGROUND: As the use of everyday technology is increasingly important for participation in daily activities, more in-depth knowledge of everyday technology use in relation to diagnosis and gender is needed. The purpose of this study was to investigate the stability of the perceived challenge of a variety of everyday technologies across different samples of varying diagnoses including both males and females. METHODS: This cross-sectional study used 643 data records from clinical and research samples, including persons with dementia or related disorders, acquired brain injury, intellectual disability, various mental or medical disorders, and adults without known diagnoses...
May 22, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29781173/discourse-and-cognition-in-speakers-with-acquired-brain-injury-abi-a-systematic-review
#4
REVIEW
Elizabeth Hill, Mary Claessen, Anne Whitworth, Mark Boyes, Roslyn Ward
BACKGROUND: Cognitive impairment, particularly of executive functioning, has been implicated in deficits in spoken discourse production following acquired brain injury (ABI). However, due to variation in the methodologies and heterogeneity of findings across studies, the nature and extent of this association is not well understood. AIMS: This review aims to synthesize the literature investigating associations between cognitive deficits and discourse impairment after ABI...
May 20, 2018: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29774594/in-vivo-characterization-of-3d-skull-and-brain-motion-during-dynamic-head-vibration-using-magnetic-resonance-elastography
#5
Ziying Yin, Yi Sui, Joshua D Trzasko, Phillip J Rossman, Armando Manduca, Richard L Ehman, John Huston
PURPOSE: To introduce newly developed MR elastography (MRE)-based dual-saturation imaging and dual-sensitivity motion encoding schemes to directly measure in vivo skull-brain motion, and to study the skull-brain coupling in volunteers with these approaches. METHODS: Six volunteers were scanned with a high-performance compact 3T-MRI scanner. The skull-brain MRE images were obtained with a dual-saturation imaging where the skull and brain motion were acquired with fat- and water-suppression scans, respectively...
May 17, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29766452/a-novel-technique-for-visualizing-and-analyzing-the-cerebral-vasculature-in-rodents
#6
Arjang Salehi, Amandine Jullienne, Kara M Wendel, Mary Hamer, Jiping Tang, John H Zhang, William J Pearce, Richard A DeFazio, Zinaida S Vexler, Andre Obenaus
We introduce a novel protocol to stain, visualize, and analyze blood vessels from the rat and mouse cerebrum. This technique utilizes the fluorescent dye, DiI, to label the lumen of the vasculature followed by perfusion fixation. Following brain extraction, the labeled vasculature is then imaged using wide-field fluorescence microscopy for axial and coronal images and can be followed by regional confocal microscopy. Axial and coronal images can be analyzed using classical angiographic methods for vessel density, length, and other features...
May 15, 2018: Translational Stroke Research
https://www.readbyqxmd.com/read/29764678/re-engaging-with-places-understanding-bio-geo-graphical-disruption-and-flow-in-adult-brain-injury-survivors
#7
Louise Meijering, Nicky Theunissen, Ant T Lettinga
Acquired Brain Injury (ABI) is one of the most common causes of disability and death in adults worldwide. After a period of rehabilitation, many ABI survivors still face complex mind/body conditions when they try to take up their former life again. Besides lasting visible impairments such as weakness and loss of body balance, there are often less obvious disabilities such as extreme fatigue, hypersensitivity for stimuli, memory, concentration and attention problems or personality changes. The aim of this paper is to understand how ABI survivors and their significant others renegotiate their engagements with everyday places, using the concepts of bio-geo-graphical disruption and flow...
May 5, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29757682/a-scoping-review-of-the-nature-and-outcomes-of-extended-rehabilitation-programmes-after-very-severe-brain-injury
#8
Lucy Knox, Jacinta M Douglas
PRIMARY OBJECTIVE: Many adults with very severe acquired brain injury (ABI) do not receive adequate rehabilitation, limiting their recovery and leading to admission to inappropriate living environments. The aim of this scoping review was to map the existing literature relating to the nature and outcomes of rehabilitation programmes for adults experiencing prolonged recovery after very severe ABI. DESIGN: A comprehensive scoping of the literature was undertaken, including systematic searching of databases, grey literature, and hand searching...
May 14, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29756478/outcome-of-serious-violent-offenders-with-psychotic-illness-and-cognitive-disorder-dealt-with-by-the-new-south-wales-criminal-justice-system
#9
Olav Nielssen, Natalia Yl Yee, Kimberlie Dean, Matthew Large
BACKGROUND: The few studies of the recidivism by people with psychotic illness and cognitive disorder who are convicted of serious violent offences and sentenced by the courts. METHOD: Re-imprisonment data were obtained for 661 individuals convicted of serious non-lethal violent offences in the District Courts of New South Wales in the years 2006 and 2007. Rates of re-imprisonment of offenders known to psychotic illness or cognitive disorder (intellectual disability or acquired brain injury) was compared to those not known to have those conditions...
May 1, 2018: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29755171/long-term-resolution-of-severe-ankle-contractures-using-botulinum-toxin-serial-casting-splinting-and-motor-retraining
#10
Joan Leung, Katarina Stroud
Purpose: Serial casting for ankle contractures is traditionally performed in prone, a position that patients may not easily tolerate. Also, although serial casting is effective in correcting contracture, its effect dissipates quickly. This case report describes a procedure for performing casting for ankle contractures in a supine or sitting position. It also describes a process that enables the effect of serial casting to be maintained long term. Client Description: The client was an adult who had suffered traumatic brain injury and severe bilateral ankle contractures...
2018: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/29755169/interrater-reliability-of-three-versions-of-the-chedoke-arm-and-hand-activity-inventory
#11
Denise Johnson, Jocelyn E Harris, Paul Stratford, Julie Richardson
Purpose: The purpose of this study was to estimate the interrater reliability of three shortened versions of the Chedoke Arm and Hand Activity Inventory (CAHAI-7, CAHAI-8, CAHAI-9) when used with persons with acquired brain injury (ABI). The CAHAI is an assessment of upper limb function with high reliability in the stroke and ABI populations. In the stroke population, three shortened versions of the measure have established reliability. Clinicians report time constraints as a barrier to using standardized assessments; thus, establishing the reliability of the shortened versions of the CAHAI in the ABI population may increase the use of this measure...
2018: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/29753889/onset-time-course-and-prediction-of-spasticity-after-stroke-or-traumatic-brain-injury
#12
REVIEW
K S Sunnerhagen, A Opheim, M Alt Murphy
OBJECTIVE: To describe spasticity from the onset of acquired brain injury, time course over the first year and factors associated with prediction of the development of spasticity METHODS: Recent relevant literature known to the authors, along with a complementary search yielding a total of 9 articles, represented the base for this scoping review. RESULTS: Spasticity can be seen in the first week after brain injury and is more common in the upper than lower extremity...
May 10, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29752909/systematic-review-of-caregiver-and-dyad-interventions-following-adult-traumatic-brain-injury
#13
REVIEW
Natalie Kreitzer, Brad G Kurowski, Tamilyn Bakas
OBJECTIVE: To describe and synthesize the existing literature of published adult TBI family caregiver and dyad intervention studies. Traumatic brain injuries (TBIs) are common and have a significant long-term impact, with some characterizing TBI as a chronic condition. Informal family caregivers of adults with TBI suffer from high rates of burnout, depression, fatigue, anxiety, lower subjective well-being, and poorer levels of physical health compared to non-caregivers. There is a critical gap in the understanding of interventions designed to address the impact of TBI on adult patients and their family caregivers...
May 9, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29750358/a-population-based-cost-effectiveness-study-of-early-genetic-testing-in-severe-epilepsies-of-infancy
#14
Katherine B Howell, Stefanie Eggers, Kim Dalziel, Jessica Riseley, Simone Mandelstam, Candace T Myers, Jacinta M McMahon, Amy Schneider, Gemma L Carvill, Heather C Mefford, Ingrid E Scheffer, A Simon Harvey
OBJECTIVE: The severe epilepsies of infancy (SEI) are a devastating group of disorders that pose a major care and economic burden on society; early diagnosis is critical for optimal management. This study sought to determine the incidence and etiologies of SEI, and model the yield and cost-effectiveness of early genetic testing. METHODS: A population-based study was undertaken of the incidence, etiologies, and cost-effectiveness of a whole exome sequencing-based gene panel (targeted WES) in infants with SEI born during 2011-2013, identified through electroencephalography (EEG) and neonatal databases...
May 11, 2018: Epilepsia
https://www.readbyqxmd.com/read/29749715/altered-resting-state-hippocampal-and-caudate-functional-networks-in-patients-with-obstructive-sleep-apnea
#15
Xiaopeng Song, Bhaswati Roy, Daniel W Kang, Ravi S Aysola, Paul M Macey, Mary A Woo, Frisca L Yan-Go, Ronald M Harper, Rajesh Kumar
INTRODUCTION: Brain structural injury and metabolic deficits in the hippocampus and caudate nuclei may contribute to cognitive and emotional deficits found in obstructive sleep apnea (OSA) patients. If such contributions exist, resting-state interactions of these subcortical sites with cortical areas mediating affective symptoms and cognition should be disturbed. Our aim was to examine resting-state functional connectivity (FC) of the hippocampus and caudate to other brain areas in OSA relative to control subjects, and to relate these changes to mood and neuropsychological scores...
May 10, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29748174/pituitary-dysfunction-and-association-with-fatigue-in-stroke-and-other-acute-brain-injury
#16
Heleen A Booij, Wietse D C Gaykema, Kamiel A J Kuijpers, Marie-José M Pouwels, Heleen M den Hertog
BACKGROUND: Poststroke fatigue (PSF) is a highly prevalent and debilitating condition. However, the etiology remains incompletely understood. Literature suggests the co-prevalence of pituitary dysfunction (PD) with stroke, and the question raises whether this could be a contributing factor to the development of PSF. This study reviews the prevalence of PD after stroke and other acquired brain injuries and its association with fatigue. SUMMARY: We performed a bibliographic literature search of MEDLINE and Embase databases for English language studies on PD in adult patients with stroke, traumatic brain injury (TBI) or aneurysmatic subarachnoid hemorrhage (aSAH)...
May 10, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29741076/monitoring-of-hospital-acquired-pneumonia-in-patients-with-severe-brain-injury-on-first-access-to-intensive-neurological-rehabilitation-first-year-of-observation
#17
Gianfranco Beghi, Antonio De Tanti, Paolo Serafini, Chiara Bertolino, Antonietta Celentano, Graziella Taormina
Nosocomial or hospital acquired pneumonia (HAP) is an illness contracted during a hospital stay, generally with onset 48 hours or more after admission to hospital, or within 14 days of discharge from hospital. HAP is divided into subgroups: Ventilator-associated pneumonia (VAP), accounting for 86% of hospital acquired pneumonia, and stroke-associated pneumonia (SAP). The incidence of SAP in neurological intensive care units (NICUs) is 4.1-56.6%, in medical intensive care units (MICUs) it is 17-50%, in stroke units it is 3...
May 9, 2018: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/29735116/inherited-and-acquired-choreas
#18
Claudio M de Gusmao, Jeff L Waugh
Chorea is a symptom of a broad array of genetic, structural, and metabolic disorders. While chorea can result from systemic illness and damage to diverse brain structures, injury to the basal ganglia, especially the putamen or globus pallidus, appears to be a uniting features of these diverse neuropathologies. The timing of onset, rate of progression, and the associated neurological or systemic symptoms can often narrow the differential diagnosis to a few disorders. Recognizing the correct etiology for childhood chorea is critical, as numerous disorders in this category are potentially curable, or are remediable, with early treatment...
April 2018: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/29733307/method-for-high-speed-stretch-injury-of-human-induced-pluripotent-stem-cell-derived-neurons-in-a-96-well-format
#19
Jack K Phillips, Sydney A Sherman, Sevan R Oungoulian, John D Finan
Traumatic brain injury (TBI) is a major clinical challenge with high morbidity and mortality. Despite decades of pre-clinical research, no proven therapies for TBI have been developed. This paper presents a novel method for pre-clinical neurotrauma research intended to complement existing pre-clinical models. It introduces human pathophysiology through the use of human induced pluripotent stem cell-derived neurons (hiPSCNs). It achieves loading pulse duration similar to the loading durations of clinical closed head impact injury...
April 20, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29732047/rehabilitation-of-upper-limb-in-children-with-acquired-brain-injury-a-preliminary-comparative-study
#20
Elena Beretta, Ambra Cesareo, Emilia Biffi, Carolyn Schafer, Sara Galbiati, Sandra Strazzer
Acquired brain injuries (ABIs) can lead to a wide range of impairments, including weakness or paralysis on one side of the body known as hemiplegia. In hemiplegic patients, the rehabilitation of the upper limb skills is crucial, because the recovery has an immediate impact on patient quality of life. For this reason, several treatments were developed to flank physical therapy (PT) and improve functional recovery of the upper limbs. Among them, Constraint-Induced Movement Therapy (CIMT) and robot-aided therapy have shown interesting potentialities in the rehabilitation of the hemiplegic upper limb...
2018: Journal of Healthcare Engineering
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