keyword
MENU ▼
Read by QxMD icon Read
search

Hanen

keyword
https://www.readbyqxmd.com/read/27900961/efficacy-and-safety-of-calcium-acetate-magnesium-carbonate-in-the-treatment-of-hyperphosphatemia-in-dialysis-patients
#1
Imed Helal, Hanene Elkateb, Hafedh Hedri, Malika Hajri, Fethi Ben Hamida
A phosphate binder combining calcium and magnesium offers an interesting therapeutic option to control hyperphosphatemia in dialysis patients. We investigated the effectiveness and tolerance of calcium acetate-magnesium carbonate (Ca-Mg). This is a 16-week prospective study including 16 dialysis patients. After an initial two-week washout period, serum phosphorus (sPho) ≥1.8 mmol/L, serum calcium (sCa) ≤2.6 mmol/L, and serum magnesium ≤1.5 mmol/L were the main inclusion criteria. The initial dose of Ca-Mg depended on sPho level and was titrated for every two weeks to have a sPho ≤ 1...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27892697/allium-roseum-l-extract-exerts-potent-suppressive-activities-on-chronic-myeloid-leukemia-k562-cell-viability-through-the-inhibition-of-bcr-abl-pi3k-akt-and-erk1-2-pathways-and-the-abrogation-of-vegf-secretion
#2
Soumaya Souid, Hanen Najjaa, Ichrak Riahi-Chebbi, Meriam Haoues, Mohamed Neffati, Ingrid Arnault, Jacques Auger, Habib Karoui, Makram Essafi, Khadija Essafi-Benkhadir
Use of plant extracts, alone or combined to the current chemotherapy as chemosensitizers, has emerged as a promising strategy to overcome tumor drug resistance. Here, we investigated the anticancer activity of Allium roseum L. extracts, a wild edible species in North Africa, on human Chronic Myeloid Leukemia (CML) K562 cells. The dehydrated aqueous extract (DAE) disturbed the cell cycle progression and induced the apoptosis of K562 cells. Chemical analysis of DAE showed a diversity of organosulfur compounds S-alk(en)yl-cysteine sulfoxides (RCSO) and high amount of allicin, suggesting that such molecule may be behind its antitumor effect...
November 28, 2016: Nutrition and Cancer
https://www.readbyqxmd.com/read/27878485/biofilms-in-bioremediation-and-wastewater-treatment-characterization-of-bacterial-community-structure-and-diversity-during-seasons-in-municipal-wastewater-treatment-process
#3
Yousra Turki, Ines Mehri, Rim Lajnef, Asma Ben Rejab, Amel Khessairi, Hanene Cherif, Hadda Ouzari, Abdennaceur Hassen
The bacterial community structure and diversity were assessed at the scale of rotating biodisk procedure (RB) in a semi-industrial pilot plant. As well, the Salmonella community was particularly monitored, and the effects of ultraviolet (UV-C254) on the bacterial community were studied. The identification of dominant bacteria revealed the presence of beneficial and useful species that could play an important role in the process of wastewater purification. Several species as Enterobacter agglomerans, Cronobacter sakazakii, and Pantoea agglomerans known for their bioremediation activities were revealed in the majority of biofilm samples...
November 22, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27872187/galactomannan-catabolism-conferred-by-a-polysaccharide-utilisation-locus-of-bacteroides-ovatus-enzyme-synergy-and-crystal-structure-of-a-%C3%AE-mannanase
#4
Viktoria Bågenholm, Sumitha K Reddy, Hanene Bouraoui, Johan Morrill, Evelina Kulcinskaja, Constance M Bahr, Oskar Aurelius, Theresa Rogers, Yao Xiao, Derek T Logan, Eric C Martens, Nicole M Koropatkin, Henrik Stålbrand
A recently identified polysaccharide utilisation locus (PUL) from Bacteroides ovatus ATCC8483 is transcriptionally upregulated during growth on galacto- and glucomannans. It encodes two putative glycoside hydrolase family 26 (GH26) β-mannanases, BoMan26A and BoMan26B, and a GH36 α-galactosidase, BoGal36A. The PUL also includes two glycan binding proteins, confirmed by β-mannan affinity electrophoresis. When this PUL was deleted, B. ovatus was no longer able to grow on locust bean galactomannan. BoMan26A primarily formed mannobiose from mannan polysaccharides...
November 21, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27842869/isolation-and-biochemical-characterisation-of-a-bacteriocin-like-substance-produced-by-bacillus-amyloliquefaciens-an6
#5
Hanen Ben Ayed, Hana Maalej, Noomen Hmidet, Moncef Nasri
This study focuses on the isolation and characterisation of a peptide with bacteriocin-like properties from Bacillus amyloliquefaciens An6. Incubation conditions were optimised, and the effects of the incubation period and of carbon and nitrogen sources were investigated. The produced bacteriocin was partially purified with ammonium sulphate precipitation, dialysis and ultrafiltration and was then biochemically characterised. Maximum bacteriocin production was achieved after 48h of incubation in a culture medium containing 20g/L starch and 10g/L yeast extract, with an initial pH 8...
December 2015: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/27825294/downregulation-of-mir-451-in-tunisian-chronic-myeloid-leukemia-patients-potential-implication-in-imatinib-resistance
#6
Ismael Soltani, Kais Douzi, Hanen Gharbi, Islem Benhassine, Mouheb Teber, Hassiba Amouri, Hind Ben Hadj Othman, Ahlem Farrah, Raihane Ben Lakhel, Salem Abbes, Samia Menif
OBJECTIVES: Resistance to imatinib has been recognized as a major challenge for the treatment of chronic myeloid leukemia (CML). Aberrant expression of miR-451 has been reported to participate in anticancer drug resistance. However, the role of miR-451 in imatinib resistance has not been investigated. The present study was undertaken to determine the expression of miR-451 in order to find a possible association between the expression of this miRNA and imatinib resistance in Tunisian CML patients...
November 9, 2016: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/27824279/agricultural-wastes-as-substrates-for-%C3%AE-glucosidases-production-by-talaromyces-thermophilus-role-of-these-enzymes-in-enhancing-waste-paper-saccharification
#7
Hanen Mallek-Fakhfakh, Jawhar Fakhfakh, Najla Masmoudi, Fatma Rezgui, Ali Gargouri, Hafedh Belghith
In the present study we investigated a potent extracellular β-glucosidases secreted by the thermophilic fungal strain AX4 of Talaromyces thermophilus, isolated from Tunisian soil samples. This strain was selected referring to the highest thermostability of its β-glucosidases compared to the other fungal isolates. The β-glucosidase production was investigated by submerged fermentation (SmF). The optimal temperature and initial pH for maximum β-glucosidase production were 50°C and 7.0, respectively. Several carbon sources were assayed for their effects on β-glucosidase production, significant yields were obtained in media containing lactose 1% (3...
November 8, 2016: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/27818279/comparative-genomics-of-tunisian-leishmania-major-isolates-causing-human-cutaneous-leishmaniasis-with-contrasting-clinical-severity
#8
Amel Ghouila, Fatma Z Guerfali, Chiraz Atri, Aymen Bali, Hanene Attia, Rabiaa M Sghaier, Ghada Mkannez, Nicholas J Dickens, Dhafer Laouini
Zoonotic cutaneous leishmaniasis caused by Leishmania (L.) major parasites affects urban and suburban areas in the center and south of Tunisia where the disease is endemo-epidemic. Several cases were reported in human patients for which infection due to L. major induced lesions with a broad range of severity. However, very little is known about the mechanisms underlying this diversity. Our hypothesis is that parasite genomic variability could, in addition to the host immunological background, contribute to the intra-species clinical variability observed in patients and explain the lesion size differences observed in the experimental model...
November 3, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27816681/use-of-juglone-as-antibacterial-and-potential-efflux-pump-inhibitors-in-staphylococcus-aureus-isolated-from-the-oral-cavity
#9
Tarek Zmantar, Hanene Miladi, Bochra Kouidhi, Yassine Chaabouni, Rihab Ben Slama, Amina Bakhrouf, Kacem Mahdouani, Kamel Chaieb
In this study the minimal inhibitory concentration (MICs) of tetracycline (Tet), erythromycin (Ery) and benzalkonium chloride (BC) in absence and in presence of a sub-MIC of juglone (Jug) were determined. In addition, the Ethidium bromide (EtBr) efflux assay was performed to assess the effect of Jug on EtBr cells accumulation. Our results showed a selective antimicrobial activity of Jug against the tested strains. A synergistic effect of Jug, drugs (Tet and Ery) and disinfectant (BC) was noticed with a reduction rate varied from 2 to 16-fold...
November 2, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/27810522/paradoxical-reaction-associated-with-cervical-lymph-node-tuberculosis-predictive-factors-and-therapeutic-management
#10
Houda Chahed, Hela Hachicha, Aida Berriche, Rim Abdelmalek, Azza Mediouni, Badreddine Kilani, Mohamed Ben Amor, Hanene Tiouiri Benaissa, Ghazi Besbes
OBJECTIVES: The aims of this study were to determine predictive factors of paradoxical reaction in patients with cervical lymph node tuberculosis (TB) and to discuss the therapeutic management of this condition. MATERIALS AND METHODS: A retrospective study was performed of 501 patients managed for cervical lymph node TB over a period of 12 years (from January 2000 to December 2011). Statistical data were analyzed using IBM SPSS Statistics version 20.0. RESULTS: Paradoxical reaction occurred in 67 patients (13...
October 31, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27788308/cover-image-volume-113-number-12-december-2016
#11
Hanen Khabou, Mélissa Desrosiers, Céline Winckler, Stéphane Fouquet, Gwenaëlle Auregan, Alexis-Pierre Bemelmans, José-Alain Sahel, Deniz Dalkara
Cover Legend A schematic representation of cell transduction with AAV particles. The cover image, by Deniz Dalkara et al., is based on the Article Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8, DOI: 10.1002/bit.26031.
December 2016: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/27776691/combination-of-tacrolimus-and-mycophenolate-mofetil-induces-oxidative-stress-and-genotoxicity-in-spleen-and-bone-marrow-of-wistar-rats
#12
Hanen Ferjani, Hossam Draz, Salwa Abid, Abedellatif Achour, Hassen Bacha, Imen Boussema-Ayed
Tacrolimus (TAC) and mycophenolate mofetil (MMF) are common immunosuppressive drugs used to avoid immunological rejection of transplanted organs. The risk of developing cancer is the most critical complication in organ transplant recipients undergoing immunosuppressive therapy. This study aims to explore the cytotoxic and genotoxic effects of TAC and MMF alone or combined orally administrated on spleen and bone marrow of Wistar rats. Our results showed that TAC (2.4; 24 and 60mg/kg) and MMF (5; 50 and 125mg/kg) induced a genotoxic effect on rat bone marrow...
November 1, 2016: Mutation Research
https://www.readbyqxmd.com/read/27726078/optimization-of-a-cationic-dye-removal-by-a-chemically-modified-agriculture-by-product-using-response-surface-methodology-biomasses-characterization-and-adsorption-properties
#13
Ahmed Amine Azzaz, Salah Jellali, Hanene Akrout, Aymen Amine Assadi, Latifa Bousselmi
The present study investigates the alkaline modification of raw orange tree sawdust (ROS) for an optimal removal of methylene blue (MB), as a cationic dye model, from synthetic solutions. The effects of operating parameters, namely, sodium hydroxide (NaOH) concentrations, ROS doses in NaOH solutions, stirring times, and initial MB concentrations on dye removal efficiency, were followed in batch mode. The process optimization was performed through the response surface methodology approach (RSM) by using Minitab17 software...
October 10, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27716525/activation-induced-cytidine-deaminase-mutant-aid-his130pro-from-hyper-igm-2-patient-retained-mutagenic-activity-on-shm-artificial-substrate
#14
Hanen Ouadani, Imen Ben-Mustapha, Meriem Ben-Ali, Beya Larguèche, Tihana Jovanic, Sylvie Garcia, Benoit Arcangioli, Houda Elloumi-Zghal, Dahmani Fathallah, Mongia Hachicha, Hatem Masmoudi, François Rougeon, Mohamed-Ridha Barbouche
Activation induced cytidine deaminase (AID) is an essential enzyme for class switch recombination (CSR) and somatic hypermutation (SHM) during secondary immune response. Mutations in the AICDA gene are responsible for Hyper IgM 2 syndrome where both CSR and SHM or only CSR are affected. Indeed, triggering either of the two mechanisms requires the DNA deamination activity of AID. Besides, different domains of AID may be differentially involved in CSR and SHM through their interaction with specific cofactors...
October 4, 2016: Molecular Immunology
https://www.readbyqxmd.com/read/27706951/inhibition-of-pancreatic-lipase-and-amylase-by-extracts-of-different-spices-and-plants
#15
Mohamed Sellami, Hanen Louati, Jannet Kamoun, Ali Kchaou, Mohamed Damak, Youssef Gargouri
The aim of this study is to search new anti-obesity and anti-diabetic agents from plant and spices crude extracts as alternative to synthetic drugs. The inhibitory effect of 72 extracts was evaluated, in vitro, on lipase and amylase activities. Aqueous extracts of cinnamon and black tea exhibited an appreciable inhibitory effect on pancreatic amylase with IC50 values of 18 and 87 μg, respectively. Aqueous extracts of cinnamon and mint showed strong inhibitory effects against pancreatic lipase with IC50 of 45 and 62 μg, respectively...
October 6, 2016: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/27704513/community-acquired-pleuropneumonia-in-children-bacteriological-and-therapeutic-challenges
#16
Samia Hamouda, Karima Chraiet, Fatma Khalsi, Imen Bel Hadj, Ines Brini, Hanen Smaoui, Sihem Barsaoui, Azza Samoud, Saida Ben Becher, Najla Ben Jaballah, Amel Kechrid, Faten Tinsa, Khadija Boussetta
Background Community-acquired pleuropneumonia (CPP) is a common complication of pneumonia in children. It is serious given its high morbidity and significant mortality. Aim To study clinical and paraclinical features of CPP in children and to establish a common therapeutic strategy. Methods Our retrospective study included patients who were hospitalized for CPP between 2004 and 2012. All data were collected from patients' medical files. Statistical analysis was made by Epi-Info 6. Results One hundred and sixty four patients were registered...
April 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/27695911/molecular-analysis-of-the-role-of-osmolyte-transporters-opuca-and-betl-in-listeria-monocytogenes-after-cold-and-freezing-stress
#17
Hanene Miladi, Hamouda Elabed, Rihab Ben Slama, Amel Rhim, Amina Bakhrouf
Listeria monocytogenes is a food-borne pathogen of humans and other animals. The striking ability to survive several stresses usually used for food preservation makes L. monocytogenes one of the biggest concerns to the food industry. This ubiquity can be partly explained by the ability of the organism to grow and persist at very low temperatures, a consequence of its ability to accumulate cryoprotective compound called osmolytes. A quantitative RT-PCR assay was used to measure mRNA transcript accumulation for the stress response genes opuCA and betL (encoding carnitine and betaine transporters, respectively) and the housekeeping gene 16S rRNA...
October 1, 2016: Archives of Microbiology
https://www.readbyqxmd.com/read/27677044/the-importance-of-fear-beliefs-catastrophizing-and-kinesiophobia-in-chronic-low-back-pain-military-rehabilitation
#18
Rim Maaoui, Emna Bahlouli, Imen Ksibi, Hanen Khiari, Hajer Rahali
OBJECTIVE: Psychosocial factors appear increasingly decisive in functional disability related to chronic low-back pain. Catastrophizing and kinesiophobia lead to deconditioning and the perpetuation of pain. The purpose of this study is to evaluate fear, beliefs, catastrophizing and kinesiophobia in chronic low-back pain patients about to begin a training programme in a rehabilitation centre. MATERIAL/PATIENTS AND METHODS: Retrospective study conducted in the department of physical and rehabilitation medicine in the Military Tunis hospital between March and June 2015, concerning patients followed for chronic low-back pain...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27668542/evaluation-of-anti-diabetic-and-anti-tumoral-activities-of-bioactive-compounds-from-phoenix-dactylifera-l-s-leaf-in-vitro-and-in-vivo-approach
#19
Mouna Chakroun, Bassem Khemakhem, Hazem Ben Mabrouk, Hanen El Abed, Mohamed Makni, Mohamed Bouaziz, Noureddine Drira, Naziha Marrakchi, Hafedh Mejdoub
Among various chronic disorders, cancer and diabetes mellitus are the most common disorders. This study was designed to evaluate the effectiveness of hydroalcoholic extract of Phoenix dactylifera L. leaves (HEPdL) in animal models of type II diabetes in vitro/in vivo and in a human melanoma-derived cell line (IGR-39). A liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis was also performed to determine the amount of phenolic and flavonoid compounds in this plant. The physicochemical results by LC-MS/MS analysis of HEPdL showed the presence of 10 phenolic compounds...
September 23, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27664691/quality-preservation-of-deliberately-contaminated-milk-using-thyme-free-and-nanoemulsified-essential-oils
#20
Mariem Ben Jemaa, Hanen Falleh, Marcos A Neves, Hiroko Isoda, Mitsutoshi Nakajima, Riadh Ksouri
The objective of this study is to evaluate the effect of either a solution of Thymus capitatus essential oil or its nanoemulsion on the quality of milk contaminated by bacteria. After 24h of S. aureus inoculation, bacterial growth reached 202×10(3)CFU/ml in the presence of the essential oil while it was limited to 132×10(3)CFU/ml when treated with nanoemulsion. The reduction of antioxidant capacity of milk treated with essential oil was higher when treated with nanoemulsion. Moreover, free essential oil was more efficient in protecting proteins from degradation than the nanoemulsion...
February 15, 2017: Food Chemistry
keyword
keyword
31219
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"