keyword
https://read.qxmd.com/read/37813356/diagnosis-and-management-of-barrett-esophagus-european-society-of-gastrointestinal-endoscopy-esge-guideline
#21
JOURNAL ARTICLE
Bas L A M Weusten, Raf Bisschops, Mario Dinis-Ribeiro, Massimiliano di Pietro, Oliver Pech, Manon C W Spaander, Francisco Baldaque-Silva, Maximilien Barret, Emmanuel Coron, Glòria Fernández-Esparrach, Rebecca C Fitzgerald, Marnix Jansen, Manol Jovani, Ines Marques-de-Sa, Arti Rattan, W Keith Tan, Eva P D Verheij, Pauline A Zellenrath, Konstantinos Triantafyllou, Roos E Pouw
MR1 : ESGE recommends the following standards for Barrett esophagus (BE) surveillance:- a minimum of 1-minute inspection time per cm of BE length during a surveillance endoscopy- photodocumentation of landmarks, the BE segment including one picture per cm of BE length, and the esophagogastric junction in retroflexed position, and any visible lesions- use of the Prague and (for visible lesions) Paris classification- collection of biopsies from all visible abnormalities (if present), followed by random four-quadrant biopsies for every 2-cm BE length...
October 9, 2023: Endoscopy
https://read.qxmd.com/read/37784845/utility-of-stereotactic-body-radiation-therapy-sbrt-in-establishing-local-control-for-invasive-breast-cancer-patients-not-undergoing-definitive-surgery
#22
JOURNAL ARTICLE
S A Polce, E Zabrocka, J D Roberson Ii, J Kim, S Ryu, A Stessin
PURPOSE/OBJECTIVE(S): Breast cancer (BC) treatment involves a multi-modal approach where surgical resection is the backbone of therapy. However, due to medical comorbidities precluding surgery, unresectable disease, or patient preference, some patients do not undergo surgery. In the absence of resection, it is paramount to improve local control (LC) of the primary tumor. To that end, this study explored the role of ablative RT dose delivered with SBRT. MATERIALS/METHODS: Between 2015-2022, 21 patients (10 metastatic, 11 stage IA-IIIC) received 23 SBRT courses to primary BC lesions without planned surgery at our institution...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784389/automatic-prediction-of-metastasis-free-survival-mfs-using-prostate-specific-membrane-antigen-psma-pet-for-oligometastatic-castration-sensitive-prostate-cancer-omcspc
#23
JOURNAL ARTICLE
Y Cao, P Sutera, W Mendes, B Yousefi, W T Hrinivich, M P Deek, R Phillips, D Song, A P Kiess, O C Guler, N Torun, M Reyhan, P T Tran, H C Onal, L Ren
PURPOSE/OBJECTIVE(S): Recent data have shown the promise of metastasis-directed therapy (MDT) to improve outcomes in omCSPC patients. Response biomarkers are still needed to identify patients at an early time point who will not respond to the treatment. We have shown that PSMA PET-CT SUVmax changes over time may be a useful response biomarker that correlates with MFS, an important endpoint in these omCSPC patients. This study investigated radiomic imaging biomarkers derived from PSMA-PET acquired pre- and post-MDT for MFS prediction, which may provide better features to discriminate response in the future to improve the outcome of these patients...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37776263/swincross-cross-modal-swin-transformer-for-head-and-neck-tumor-segmentation-in-pet-ct-images
#24
JOURNAL ARTICLE
Gary Y Li, Junyu Chen, Se-In Jang, Kuang Gong, Quanzheng Li
BACKGROUND: Radiotherapy (RT) combined with cetuximab is the standard treatment for patients with inoperable head and neck cancers. Segmentation of head and neck (H&N) tumors is a prerequisite for radiotherapy planning but a time-consuming process. In recent years, deep convolutional neural networks (DCNN) have become the de facto standard for automated image segmentation. However, due to the expensive computational cost associated with enlarging the field of view in DCNNs, their ability to model long-range dependency is still limited, and this can result in sub-optimal segmentation performance for objects with background context spanning over long distances...
September 30, 2023: Medical Physics
https://read.qxmd.com/read/37658557/lung-cancer-ct-guided-bx-ebus-how-and-when
#25
JOURNAL ARTICLE
Miltiadis Krokidis
Histological diagnosis is mandatory for the majority of solid lesions in the lungs in order to characterize the lesions but also to assess the response to treatment. Flexible bronchoscopy has a variable and often poor success rate in sampling pulmonary lesions which are not visible endoscopically. Such focal radiological opacities without endobronchial extension are referred to as peripheral pulmonary lesions and sampling is usually performed under guidance with computed tomography that is a safe and effective technique and became a common procedure representing an essential step for diagnosis and treatment planning...
2023: Hellenic Journal of Nuclear Medicine
https://read.qxmd.com/read/37657020/the-evolution-of-primary-hyperparathyroidism-publications-and-global-productivity-from-past-to-present-a-bibliometric-analysis-during-1980-to-2022
#26
JOURNAL ARTICLE
Hüseyin Göbüt, Hasan Bostanci
The aim of this study was to perform a descriptive analysis of scientific articles about primary hyperparathyroidism (PHPT) using bibliometric approaches. By analyzing the links between the various research components (authors, journals, institutions, countries) of the academic outputs, it was aimed to summarize the intellectual structure of PHPT, identify recent research trends, and determine the global productivity. Three thousand nine hundred fifty-four articles on PHPT published between 1980 and 2022 were pulled from the Web of Science database and analyzed using bibliometric approaches...
September 1, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37644167/a-dual-tracer-approach-using-11-c-ch-and-18-f-fdg-in-hcc-clinical-decision-making
#27
JOURNAL ARTICLE
Emile B Veenstra, Simeon J S Ruiter, Robbert J de Haas, Koert P de Jong, Paola A Erba, Rudi A J O Dierckx, Walter Noordzij
BACKGROUND: Early detection of recurrent or progressive HCC remains the strongest prognostic factor for survival. Dual tracer PET/CT imaging with [11 C]CH and [18 F]FDG can further increase detection rates as both tracers entail different metabolic pathways involved in HCC development. We investigated dual-tracer PET/CT in clinical decision making in patients suspected of recurrent or progressive HCC. All HCC patients who underwent both [11 C]CH and [18 F]FDG PET/CT in our institute from February 2018 to December 2021 were included...
August 29, 2023: EJNMMI Research
https://read.qxmd.com/read/37623020/percutaneous-radiofrequency-ablation-of-thyroid-carcinomas-ineligible-for-surgery-in-the-elderly
#28
Pierre Yves Marcy, Marc Tassart, Jean-Guillaume Marchand, Juliette Thariat, Alain Bizeau, Edouard Ghanassia
Thirty to 50% of differentiated thyroid carcinomas include papillary thyroid microcarcinomas (mPTC). Most of these tumors remain clinically silent, have a bright prognosis and a disease-specific mortality <1%. Surgery has been recommended as first line-treatment by current guidelines, the standard treatment being lobectomy. However, surgery has some drawbacks, including potential recurrent laryngeal nerve paralysis, hypothyroidism, hypoparathyroidism, in -patient basis hospital stay, lifelong medication, scarring of the neck, and general anesthesia related risks...
August 6, 2023: Current Oncology
https://read.qxmd.com/read/37491521/the-added-diagnostic-value-of-transcatheter-ct-hepatic-arteriography-for-intraprocedural-detection-of-previously-unknown-colorectal-liver-metastases-during-percutaneous-ablation-and-impact-on-the-definitive-treatment-plan
#29
JOURNAL ARTICLE
Susan van der Lei, Jip Opperman, Madelon Dijkstra, Nikita Kors, Rianne Boon, Bente A T van den Bemd, Florentine E F Timmer, Irene M G C Nota, Janneke E van den Bergh, Jan J J de Vries, Hester J Scheffer, Bart Geboers, Timothy Neuss, Evelien Schouten, Birgit I Lissenberg-Witte, Robbert S Puijk, Martijn R Meijerink
PURPOSE: This study assessed the diagnostic value of CT hepatic arteriography (CTHA) for the intraprocedural detection of previously unknown colorectal liver metastases (CRLM) and the impact on the definitive treatment plan. MATERIALS AND METHODS: All patients treated with CTHA-guided percutaneous ablation for CRLM between January 2012 and March 2022 were identified from the Amsterdam Colorectal Liver Met Registry (AmCORE). Radiology reports of the ablative procedure and follow-up imaging were reviewed to see if (a) previously unknown CRLM were detected intra-procedurally and if (b) new CRLM, potentially missed on CTHA, appeared within 6 months following the procedure; three abdominal radiologists re-reviewed the baseline CTHA scans of these patients with early recurrence...
July 25, 2023: Cardiovascular and Interventional Radiology
https://read.qxmd.com/read/37478044/gesenet-a-general-semantic-guided-network-with-couple-mask-ensemble-for-medical-image-fusion
#30
JOURNAL ARTICLE
Jiawei Li, Jinyuan Liu, Shihua Zhou, Qiang Zhang, Nikola K Kasabov
At present, multimodal medical image fusion technology has become an essential means for researchers and doctors to predict diseases and study pathology. Nevertheless, how to reserve more unique features from different modal source images on the premise of ensuring time efficiency is a tricky problem. To handle this issue, we propose a flexible semantic-guided architecture with a mask-optimized framework in an end-to-end manner, termed as GeSeNet. Specifically, a region mask module is devised to deepen the learning of important information while pruning redundant computation for reducing the runtime...
July 21, 2023: IEEE Transactions on Neural Networks and Learning Systems
https://read.qxmd.com/read/37477423/salvage-surgery-for-local-recurrences-after-stereotactic-ablative-radiotherapy-of-colorectal-pulmonary-metastases
#31
JOURNAL ARTICLE
Martijn van Dorp, Semih Ünal, Simone Gooijer, Chris Dickhoff, Frank Jozef Christiaan van den Broek, Geert Kazemier, Wilhelmina Hendrika Schreurs, Famke Lorelei Schneiders, Max Dahele, David Jonathan Heineman
INTRODUCTION: Local control following stereotactic ablative radiotherapy (SABR) for patients with colorectal pulmonary metastases is reportedly lower than for metastases from other tumors. Such recurrences may still be amenable to salvage therapy. We describe our experience with salvage surgery in 17 patients. METHODS: Patients who underwent salvage metastasectomy for a local recurrence following SABR for colorectal pulmonary metastases were identified from the surgical institutional databases of three Dutch major referral hospitals...
July 21, 2023: Journal of Surgical Oncology
https://read.qxmd.com/read/37455674/multimodal-fusion-workflow-for-target-delineation-in-cardiac-radioablation-of-ventricular-tachycardia
#32
JOURNAL ARTICLE
Louis Rigal, Karim Benali, Valentin Barré, Mathilde Bougault, Julien Bellec, Renaud De Crevoisier, Raphaël Martins, Antoine Simon
BACKGROUND: Cardiac radioablation (CR) is an innovative treatment to ablate cardiac arrythmia sources by radiation therapy. CR target delineation is a challenging task requiring the exploitation of highly different imaging modalities, including cardiac electro-anatomical mapping (EAM). PURPOSE: In this work, a data integration process is proposed to alleviate the tediousness of CR target delineation by generating a fused representation of the heart, including all the information of interest resulting from the analysis and registration of electro-anatomical data, PET scan and planning computed tomography (CT) scan...
July 17, 2023: Medical Physics
https://read.qxmd.com/read/37408912/a-comparative-study-of-establishing-rabbit-vertebral-tumor-model-by-two-ways-of-ct-guided-percutaneous-puncture
#33
JOURNAL ARTICLE
Zhilong Wang, Taiyang Zuo, Wenli Lin, Yining Liang, Fangzhou Jiang, Yibing Li
OBJECTIVE: To investigate the difference of tumor formation rate of rabbit vertebral tumor model established by percutaneous injection of V×2 tumor tissue suspension and tumor mass under computed tomography (CT) guidance, and the imaging findings of CT, magnetic resonance images (MRI) and positron emission tomography with computed tomography (PET/CT) at 7 days, 14 days and 21 days after implantation, and preliminarily verify the safety and feasibility of microwave ablation (MWA), percutaneous vertebroplasty (PVP) and microwave ablation combined with percutaneous vertebroplasty (MWA + PVP) in rabbit VX2 vertebral tumor model...
June 2023: Heliyon
https://read.qxmd.com/read/37408818/primary-hepatic-extra-gastrointestinal-stromal-tumors-molecular-pathogenesis-immunohistopathology-and-treatment
#34
REVIEW
Erica C Becker, Gonca Ozcan, George Y Wu
Gastrointestinal stromal tumors are the most common mesenchymal tumors of the gastrointestinal tract. They originate from the interstitial cells of Cajal and are usually found in extrahepatic gastrointestinal sites. However, a small subset are derived from the liver and are known as primary hepatic gastrointestinal stromal tumors (PHGIST). They have a poor prognosis and are historically difficult to diagnose. Our objective was to review and update the latest evidence-based knowledge concerning PHGIST, with a focus on epidemiology, etiology, pathophysiology, clinical presentation, histopathology, and treatment...
August 28, 2023: Journal of Clinical and Translational Hepatology
https://read.qxmd.com/read/37395949/stereotactic-body-radiation-therapy-salvage-for-lymph-node-recurrent-prostate-cancer-in-the-era-of-psma-pet-imaging
#35
REVIEW
Omar E Hayek, Soroush Rais-Bahrami, Andrew McDonald, Samuel J Galgano
PURPOSE OF REVIEW: Our understanding of patterns of prostate cancer recurrence after primary treatment of localized disease has significantly evolved since the development of positron emission tomography (PET) agents targeting prostate cancer. Previously, most biochemical recurrences were not associated with imaging correlates when restaging with computed tomography (CT), magnetic resonance imaging (MRI), or bone scintigraphy and, hence, were typically assumed to represent occult metastases...
July 3, 2023: Current Urology Reports
https://read.qxmd.com/read/37358989/focal-therapy-of-prostate-cancer-assessment-with-prostate-specific-membrane-antigen-psma-imaging
#36
Mark Topoozian, Jeremie Calais, Ely Felker, Anthony Sisk, Samantha Gonzalez, Sean J Lee, Leonard S Marks
Focal therapy of prostate cancer (PCa) is currently of great interest, but a metric of success. other than biopsy, is not yet available. In a patient with a repeatedly negative MRI and negative systematic biopsies, a scan employing the radioisotope 68 Ga-PSMA-11 PET/CT identified a PSMA-avid hotspot in the prostate. PSMA-guided biopsy confirmed the diagnosis of a clinically-significant PCa. Following ablation of the lesion with high-intensity focused ultrasound (HIFU), the PSMA-avid lesion disappeared and targeted biopsy confirmed a fibrotic scar with no residual cancer...
September 2023: Urology Case Reports
https://read.qxmd.com/read/37352467/simultaneous-delivery-of-dual-inhibitors-of-dna-damage-repair-sensitizes-pancreatic-cancer-response-to-irreversible-electroporation
#37
JOURNAL ARTICLE
Xin Long, Anna Dai, Teng Huang, Wenhao Niu, Luoxia Liu, Hui Xu, Tao Yin, Tian'an Jiang, Shuguo Sun, Ping Lei, Chun Li, Xiaohua Zhu, Jun Zhao
Pancreatic ductal adenocarcinoma (PDAC) is an abysmal disease refractory to most standard therapies. Irreversible electroporation (IRE) is a local ablative technique for the clinical treatment of solid tumors, including locally advanced and unresectable PDAC, by intratumorally delivering high-intensity electric pulses to permanently disrupt cell membranes and induce cell death. But the distribution of electric field is uneven within the tumor, and in some regions, tumor cells only experience temporary perturbation to their cell membrane, a phenomenon denoted as reversible electroporation (RE)...
June 23, 2023: ACS Nano
https://read.qxmd.com/read/37327318/-gold-nanostars-obviate-limitations-to-laser-interstitial-thermal-therapy-litt-for-the-treatment-of-intracranial-tumors
#38
JOURNAL ARTICLE
Ethan S Srinivasan, Yang Liu, Ren A Odion, Pakawat Chongsathidkiet, Lucas P Wachsmuth, Aden P Haskell-Mendoza, Ryan M Edwards, Aidan J Canning, Gavin Willoughby, Joseph Hinton, Stephen J Norton, Christopher D Lascola, Paolo F Maccarini, Christopher L Mariani, Tuan Vo-Dinh, Peter E Fecci
PURPOSE: Laser interstitial thermal therapy (LITT) is an effective minimally-invasive treatment option for intracranial tumors. Our group produced plasmonics-active gold nanostars (GNS) designed to preferentially accumulate within intracranial tumors and amplify the ablative capacity of LITT. EXPERIMENTAL DESIGN: The impact of GNS on LITT coverage capacity was tested in ex vivo models utilizing clinical LITT equipment and agarose gel-based phantoms of control and GNS-infused central "tumors"...
June 16, 2023: Clinical Cancer Research
https://read.qxmd.com/read/37306856/automated-full-body-tumor-segmentation-in-dotatate-pet-ct-for-neuroendocrine-cancer-patients
#39
JOURNAL ARTICLE
Alice Santilli, Prashanth Panyam, Arthur Autz, Rick Wray, John Philip, Pierre Elnajjar, Nathaniel Swinburne, Marius Mayerhoefer
PURPOSE: Neuroendocrine tumors (NETs) are a rare form of cancer that can occur anywhere in the body and commonly metastasizes. The large variance in location and aggressiveness of the tumors makes it a difficult cancer to treat. Assessments of the whole-body tumor burden in a patient image allow for better tracking of disease progression and inform better treatment decisions. Currently, radiologists rely on qualitative assessments of this metric since manual segmentation is unfeasible within a typical busy clinical workflow...
June 12, 2023: International Journal of Computer Assisted Radiology and Surgery
https://read.qxmd.com/read/37304318/unusual-phosphaturic-mesenchymal-tumor-mimicking-osteoid-osteoma
#40
Elsa Hervier, Karel Gorican, Sana Boudabbous, Emmanuel Biver, Serge Ferrari, Essia Saiji, Valentina Garibotto, Ismini Mainta
Phosphaturic mesenchymal tumor is a rare tumor characterized by paraneoplastic osteomalacia. The diagnosis is often delayed because of nonspecific symptoms and difficulty to localize the tumor. In this study we report a case of PMT of the left femur detected by Ga-68-DOTATATE PET-CT with radiological features mimicking osteoid osteoma. We report a 31-year-old female patient who presented to our hospital for evaluation due to progressive bone pain and muscle weakness. Her laboratory data showed hypophosphatemia and increased fibroblast growth factor 23 (FGF-23) together with reduced bone mineral density on bone densitometry...
August 2023: Radiology Case Reports
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