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https://www.readbyqxmd.com/read/27894853/concurrent-carpal-tunnel-syndrome-and-pronator-syndrome-a-retrospective-study-of-21-cases
#1
Chih-Wei Hsiao, Jui-Tein Shih, Sheng-Tsai Hung
PURPOSE: Concurrent carpal tunnel syndrome and pronator syndrome are rarely considered and the proximal compression sites are easily overlooked. We retrospectively studied 21 concurrent cases in our series from 2009 to 2015 and report the results. PATIENTS AND METHODS: The typical symptoms were pain, tingling, and numbness of the radial 3½ digits. If paresthesia involved the thenar eminence and proximal forearm pain was noted in cases of carpal tunnel syndrome, carpal tunnel syndrome combined with pronator syndrome was considered...
November 25, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27890336/complications-and-revision-amputation-following-trauma-related-lower-limb-loss
#2
Eric Edison Low, Elizabeth Inkellis, Saam Morshed
INTRODUCTION: Trauma-related amputations are a common cause of limb loss in the United States. Despite the military and public health impact of trauma-related amputations, distributions of various lower limb amputations and the relative frequency of complications and revision amputations have not been well described. We used the National Trauma Data Bank (NTDB) in order to investigate the epidemiology of trauma-related lower extremity amputations among civilians in U.S. trauma centers...
November 18, 2016: Injury
https://www.readbyqxmd.com/read/27887768/evaluation-of-acute-kidney-injury-using-contrast-ultrasonography-in-a-rabbit-model-of-crush-syndrome
#3
Chundong Zhang, Xin Wang, Jie Tang
This study aimed to investigate the feasibility of evaluating acute kidney injury (AKI) using contrast ultrasonography in a rabbit model of crush syndrome. Sixty-four New Zealand white rabbits were anesthetized and the left hind limb was wrapped and compressed for 4 h with a sphygmomanometer. Contrast ultrasonography of the left kidney using microbubbles as the contrast medium was performed. The serum levels of blood urea nitrogen (BUN), creatine (Cr), creatine kinase (CK) and lactate dehydrogenase (LDH) were significantly increased in comparison to before the compression...
November 22, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27874086/combined-administration-of-anisodamine-and-neostigmine-rescued-acute-lethal-crush-syndrome-through-%C3%AE-7nachr-dependent-jak2-stat3-signaling
#4
Zhe-Qi Xu, Bo-Zong Shao, Ping Ke, Jian-Guo Liu, Guo-Ku Liu, Xiong-Wen Chen, Ding-Feng Su, Chong Liu
Previously we showed that Ani (anisodamine)/Neo (neostigmine) combination produced anti-shock effect via activating α7 nicotinic acetylcholine receptor (α7nAChR). In this study, we aim to investigate the therapeutic effect and underlying mechanisms of Ani/Neo combination in acute lethal crush syndrome (CS). In rat and rabbit CS models, Ani/Neo combination increased the 24 h survival rates, improved hemodynamics and decreased the levels of creatine kinase, MB isoenzyme of creatine kinase, blood urea nitrogen, creatinine, K(+) in serum...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27823994/optimized-axillary-vein-technique-versus-subclavian-vein-technique-in-cardiovascular-implantable-electronic-device-implantation-a-randomized-controlled-study
#5
Peng Liu, Yi-Feng Zhou, Peng Yang, Yan-Sha Gao, Gui-Ru Zhao, Shi-Yan Ren, Xian-Lun Li
BACKGROUND: The conventional venous access for cardiovascular implantable electronic device (CIED) is the subclavian vein, which is often accompanied by high complication rate. The aim of this study was to assess the efficacy and safety of optimized axillary vein technique. METHODS: A total of 247 patients undergoing CIED implantation were included and assigned to the axillary vein group or the subclavian vein group randomly. Success rate of puncture and complications in the perioperative period and follow-ups were recorded...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27777548/crush-syndrome-chez-l%C3%A2-adulte-et-problematique-de-sa-prise-en-charge-a-la-phase-aigu%C3%A3
#6
P F Hemou, H D Sama, P Tchétikè, T Potkar
Le crush syndrome se définit comme l'ensemble des manifestations locales et générales secondaires à une rhabdomyolyse traumatique avec ischémie de grosses masses musculaires par compression prolongée, à l'origine d'un syndrome compartimental ou syndrome des loges. Rarement isolé, il peut passer inaperçu dans les 24 à 48 premières heures de la phase aiguë d'un traumatisme sévère quand les principales préoccupations médicales sont la sauvegarde des fonctions vitales. La souffrance musculaire liée au syndrome compartimental entraîne la libération de myoglobine dans la circulation générale...
December 31, 2015: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/27770520/changes-of-endothelin-1-content-and-blood-rheological-properties-in-crush-syndrome
#7
N Gamkrelidze, N Pavliashvili, R Otarashvili
This study describes hematocrit values and quantitative changes in plasma endothelin-1 (ET-1) levels according to the severity of crush syndrome (CS) compression and decompression periods. The experiments were carried out on 50 randomly selected 200-250 gr mass Wistar rats with the use of the standard crush syndrome modeling method. The plasma level of ET-1 was determined by the immuneenzyme method with the use of ELISA REDEAR URIT 660. Hematocrit was determined using the standard method and measured according to tube column divisions...
September 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27767408/a-case-of-acute-pericarditis-following-intravenous-injection-of-crushed-morphine-tablets
#8
Ryan J Anderson, Bryan Corbett, Binh T Ly
A 37-year-old male presented with sharp, severe chest pain following seven days of intravenous injection of crushed morphine tablets. The chest pain was positional and pleuritic in nature and resolved with leaning forward. Work-up was notable for an ECG with inferior and anterolateral PR depressions as well as a CT chest with diffuse centrilobular nodules. Per radiology, the CT findings along with the patient's history were concerning for pulmonary granulomatosis from deposition of talc or some other foreign body...
November 2016: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/27751780/multifocal-neuropathy-expanding-the-scope-of-double-crush-syndrome
#9
Brian H Cohen, Michael P Gaspar, Alan H Daniels, Edward Akelman, Patrick M Kane
Double crush syndrome (DCS), as it is classically defined, is a clinical condition composed of neurological dysfunction due to compressive pathology at multiple sites along a single peripheral nerve. The traditional definition of DCS is narrow in scope because many systemic pathologic processes, such as diabetes mellitus, drug-induced neuropathy, vascular disease and autoimmune neuronal damage, can have deleterious effects on nerve function. Multifocal neuropathy is a more appropriate term describing the multiple etiologies (including compressive lesions) that may synergistically contribute to nerve dysfunction and clinical symptoms...
October 14, 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27734449/management-of-crush-syndrome-under-prolonged-field-care
#10
Thomas J Walters, Douglas Powell, Andrew Penny, Ian Stewart, Kevin Chung, Sean Keenan, Stacy Shackelford
No abstract text is available yet for this article.
2016: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/27703959/a-systematic-review-of-iranian-experiences-in-seismo-nephrology
#11
Behrooz Hashemi, Saeed Safari, Mostafa Hosseini, Mahmoud Yousefifard, Elham Erfani, Alireza Baratloo, Farhad Rahmati, Maryam Motamedi, Mohammad Mehdi Forouzanfar, Iraj Najafi
CONTEXT: Crush syndrome and its potentially life-threatening complications, such as acute kidney injury (AKI), are one of the most important medical problems of disaster victims. However, today, many unanswered questions abound about the potential risk factors of crush syndrome, predictive factors of AKI, proper amount of prophylactic hydration therapy, type of fluid, time of continuing fluid, intravenous versus oral hydration, etc. Therefore, this study was designed to review the findings on Iranian nephrologist experiences in diagnosis and management of traumatic rhabdomyolysis following the last two strong earthquakes of Bam (2003) and Manjil-Rudbar (1990)...
June 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/27627055/outcomes-following-peripheral-nerve-decompression-with-and-without-associated-double-crush-syndrome-a-case-control-study
#12
Lauren E Wessel, Duretti T Fufa, R Bruce Canham, Adam La Bore, Martin I Boyer, Ryan P Calfee
BACKGROUND: Double crush syndrome, the association between proximal and distal nerve lesions, has been established. This investigation compares the outcomes of nerve surgery in patients with isolated peripheral compression versus those with double crush syndrome treated with peripheral nerve and cervical spine surgeries. METHODS: This case controlled study enrolled 80 patients; 40 underwent carpal or cubital tunnel surgery and cervical spine surgery (double crush group) and 40 controls, matched by age and sex, underwent only peripheral nerve decompression (peripheral nerve group)...
September 10, 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27590896/cannabis-sativa-allergy-looking-through-the-fog
#13
Ine I Decuyper, Athina L Van Gasse, Nathalie Cop, Vito Sabato, Margaretha Faber, Christel Mertens, Chris H Bridts, Margo M Hagendorens, Luc De Clerck, H P Rihs, Didier G Ebo
IgE-mediated Cannabis (C. sativa, marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may trigger a C. sativa sensitization and/or allergy. The clinical presentation of a C. sativa allergy varies from mild to life-threatening reactions and often seems to depend on the route of exposure. In addition, sensitization to cannabis allergens can result in various cross-allergies, mostly for plant foods. This clinical entity, designated as the "cannabis-fruit/vegetable syndrome" might also imply cross-reactivity with tobacco, natural latex and plant-food derived alcoholic beverages...
September 3, 2016: Allergy
https://www.readbyqxmd.com/read/27582323/early-therapeutic-intervention-for-crush-syndrome-characterization-of-intramuscular-administration-of-dexamethasone-by-pharmacokinetic-and-biochemical-parameters-in-rats
#14
Isamu Murata, Mai Goto, Masahiro Komiya, Risa Motohashi, Momoko Hirata, Yutaka Inoue, Ikuo Kanamoto
Crush syndrome (CS) is the systemic manifestation of muscle cell damage resulting from pressure and crushing. It is associated with a high mortality rate, even when patients are treated with conventional therapy. We demonstrated the utility of intramuscular administration of dexamethasone (DEX) in disaster medical care by using a model of CS to characterize the pharmacokinetics and biochemical parameters. We compared intravenous (IV) and intramuscular (IM) injection. The IM sites were the right anterior limb (AL), bilateral hind limbs (bHL), and unilateral hind limb (uHL)...
2016: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/27578379/the-relationship-between-timing-of-admission-to-a-hospital-and-severity-of-injuries-following-2005-pakistan-earthquake
#15
Qamar-Hafeez Kiani, Mudassar Qazi, Adil Khan, Muhammad Iqbal
PURPOSE: The objective of this study was to establish the relationship between the timing of admission to a hospital and the severity of injuries following an earthquake. METHODS: It was a retrospective chart review of injured patients admitted to a tertiary care teaching hospital following the 2005 Pakistan earthquake. Age, gender, injury severity score, type of injuries, complications, operations, hospital stay and mortality were studied and compared at different time intervals using SPSS...
August 1, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/27561267/evaluation-of-the-pharmacokinetics-of-glibenclamide-tablet-given-off-label-orally-to-children-suffering-from-neonatal-syndromic-hyperglycemia
#16
Naïm Bouazza, Zoubir Djerada, Claire Gozalo, Kanetee Busiah, Jacques Beltrand, Marianne Berdugo, Saik Urien, Jean-Marc Treluyer, Michel Polak
PURPOSE: Glibenclamide (Gb) is used in type II diabetes mellitus but also in the last 10 years, off label, in patients with neonatal syndromic hyperglycemia carrying a mutation of Kir6.2 or SUR1. No studies have reported Gb pharmacokinetics in children. In this study, oral Gb pharmacokinetics was investigated in children in order to describe the concentration time courses, the influence of covariates, and the relationships between drug concentrations and efficacy. METHODS: Gb concentrations were measured in 18 children after the switch from subcutaneous insulin to oral tablets of Gb (crushed tablets for 33 % of patients)...
November 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27467574/neuron-specific-deletion-of-the-nf2-tumor-suppressor-impairs-functional-nerve-regeneration
#17
Alexander Schulz, Robert Büttner, Andrea Toledo, Stephan L Baader, Julia von Maltzahn, Andrey Irintchev, Reinhard Bauer, Helen Morrison
In contrast to axons of the central nervous system (CNS), axons of the peripheral nervous system (PNS) show better, but still incomplete and often slow regeneration following injury. The tumor suppressor protein merlin, mutated in the hereditary tumor syndrome Neurofibromatosis type 2 (NF2), has recently been shown to have RhoA regulatory functions in PNS neurons-in addition to its well-characterized, growth-inhibitory activity in Schwann cells. Here we report that the conditional knockout of merlin in PNS neurons leads to impaired functional recovery of mice following sciatic nerve crush injury, in a gene-dosage dependent manner...
2016: PloS One
https://www.readbyqxmd.com/read/27464346/zika-virus-an-emergent-neuropathological-agent
#18
REVIEW
Martyn K White, Hassen S Wollebo, J David Beckham, Kenneth L Tyler, Kamel Khalili
The emergence of Zika virus in the Americas has followed a pattern that is familiar from earlier epidemics of other viruses, where a new disease is introduced into a human population and then spreads rapidly with important public health consequences. In the case of Zika virus, an accumulating body of recent evidence implicates the virus in the etiology of serious pathologies of the human nervous system, that is, the occurrence of microcephaly in neonates and Guillain-Barré syndrome in adults. Zika virus is an arbovirus (arthropod-borne virus) and a member of the family Flaviviridae, genus Flavivirus...
October 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27355403/the-beneficial-effects-of-ets-gs-a-novel-vitamin-e-derivative-on-a-rat-model-of-crush-injury
#19
Junichiro Nakagawa, Naoya Matsumoto, Yuko Nakane, Kazuma Yamakawa, Tomoki Yamada, Hisatake Matsumoto, Junya Shimazaki, Yukio Imamura, Hiroshi Ogura, Takashi Jin, Takeshi Shimazu
Crush syndrome is a devastating condition leading to multiple organ failure. The mechanisms by which local traumatic injuries affect distant organs remain unknown. ETS-GS is a novel water-soluble, stable anti-oxidative agent composed of vitamin E derivative. Given that one of the main pathophysiological effects in crush syndrome is massive ischemia-reperfusion, reactive oxygen species (ROS) generated from the injured extremities would be systemically involved in distant organ damage. We investigated whether ETS-GS could suppress inflammatory response and improve mortality in a rat model of crush injury...
December 2016: Shock
https://www.readbyqxmd.com/read/27301374/beyond-muscle-destruction-a-systematic-review-of-rhabdomyolysis-for-clinical-practice
#20
REVIEW
Luis O Chavez, Monica Leon, Sharon Einav, Joseph Varon
BACKGROUND: Rhabdomyolysis is a clinical syndrome that comprises destruction of skeletal muscle with outflow of intracellular muscle content into the bloodstream. There is a great heterogeneity in the literature regarding definition, epidemiology, and treatment. The aim of this systematic literature review was to summarize the current state of knowledge regarding the epidemiologic data, definition, and management of rhabdomyolysis. METHODS: A systematic search was conducted using the keywords "rhabdomyolysis" and "crush syndrome" covering all articles from January 2006 to December 2015 in three databases (MEDLINE, SCOPUS, and ScienceDirect)...
June 15, 2016: Critical Care: the Official Journal of the Critical Care Forum
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