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https://www.readbyqxmd.com/read/29782639/sudden-cardiac-death-in-athletes-and-the-value-of-cardiovascular-magnetic-resonance
#1
REVIEW
Sophie I Mavrogeni, Flora Bacopoulou, Despoina Apostolaki, George P Chrousos
Sudden cardiac death (SCD) is the non-traumatic death, due to loss of heart function that occurs suddenly and unexpectedly within 6 hours of a previously normal state of health. It is related to intense competitive sports promoting ventricular tachycardia (VT)/ventricular fibrillation (VF) in the presence of underlying abnormal substrate. A serial evaluation of cardiac physiologic changes taking place during training will allow the better understanding of athlete's heart and will facilitate its discrimination from other gray-zone cardiomyopathies...
May 21, 2018: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29775213/individual-specific-qt-interval-correction-for-drugs-with-substantial-heart-rate-effect-using-holter-ecgs-extracted-over-a-wide-range-of-heart-rates
#2
Gopi Krishna Panicker, Pramod Kadam, Saikat Chakraborty, Snehal Kothari, J Rick Turner, Dilip R Karnad
Although fixed QT correction methods are typically used to adjust for the effect of heart rate on the QT interval in thorough QT/QTc studies, individual-specific QT correction (QTcI = QT/RRI ) is advisable for drugs that increase the heart rate by >5 to 10 beats/minute (bpm). QTcI is traditionally derived using resting drug-free electrocardiograms (ECGs) collected at prespecified times. However, the resting heart rate range in healthy individuals is narrow, and extrapolation of inferences from these data to higher heart rates could be inappropriate...
May 18, 2018: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29774304/arrhythmogenic-right-ventricular-cardiomyopathy-in-boxer-dogs-the-diagnosis-as-a-link-to-the-human-disease
#3
Annina S Vischer, David J Connolly, Caroline J Coats, Virginia Luis Fuentes, William J McKenna, Silvia Castelletti, Antonios A Pantazis
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a myocardial disease with an increased risk for ventricular arrhythmias. The condition, which occurs in Boxer dogs, shares phenotypic features with the human disease arrhythmogenic cardiomyopathy (ACM) suggesting its potential as a natural animal model. However, there are currently no universally accepted clinical criteria to diagnose ARVC in Boxer dogs. We aimed to identify diagnostic criteria for ARVC in Boxer dogs defining a more uniform and consistent phenotype...
September 2017: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/29754204/diagnosing-arvc-in-pediatric-patients-applying-the-revised-task-force-criteria-importance-of-imaging-12-lead-ecg-and-genetics
#4
Michael Steinmetz, Ulrich Krause, Peter Lauerer, Frank Konietschke, Randolph Aguayo, Christian Oliver Ritter, Andreas Schuster, Joachim Lotz, Thomas Paul, Wieland Staab
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a potentially lethal disease that is well described in adults. In pediatric patients, however, identification of patients at risk of adverse events of ARVC remains a challenge. We aimed to determine which criteria of the revised Task Force Criteria (rTFC), alone or combined, have an impact on diagnosis of ARVC when compared to disease-specific genetic mutations in pediatric patients ≤ 18 years. Between September 2010 and December 2013, 48 consecutive young patients ≤ 18 years of age (mean 14, range of 12...
May 12, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29753425/-the-contribution-of-systematic-implementation-of-cardiovascular-explorations-for-the-detection-of-cardiac-sources-of-embolism-in-patients-with-stroke-about-230-patients
#5
A Hadi, L Bendriss, A Khatouri
OBJECTIVES: Ischemic stroke are estimated at 80% of all strokes. Embolism of cardiac origin accounts for around 20% of them. The aim of our study is to report the contribution of cardiovascular investigations performed as a routine during the evaluation of patients with ischemic stroke. PATIENTS AND METHODS: This is a retrospective study of ischemic stroke cases collated in Cardiology department of the military hospital of Marrakech between January 2010 and December 2014...
May 9, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29745872/effects-of-autonomic-dysfunction-on-exercise-tolerance-in-systemic-sclerosis-patients-without-clinical-and-instrumental-evidence-of-cardiac-and-pulmonary-involvement
#6
Marcello Di Paolo, Antonietta Gigante, Marta Liberatori, Liborio Sardo, Paolo Marinelli, Marco Rossetti, Paolo Palange, Luigi Tubani, Edoardo Rosato
OBJECTIVES: Autonomic dysfunction (AD) in systemic sclerosis (SSc) was already confirmed through heart rate variability (HRV) analysis. Cardio-pulmonary exercise testing (CPET) is a useful tool in early detection of exercise tolerance in SSc patients. Aim of the study was to assess the relationships existing between AD and exercise tolerance. METHODS: Thirty-two [4 M, 28 F; median age: 47.5 (20-65) years] consecutive SSc patients were enrolled. All patients underwent pulmonary function testing, incremental symptom-limited CPET and twenty-four hours ECG Holter recording with HRV analysis in time and frequency domain...
May 4, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29740701/characteristics-and-circadian-distribution-of-cardiac-arrhythmias-in-patients-with-heart-failure-and-sleep-disordered-breathing
#7
Hazem Omran, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg, Henrik Fox
BACKGROUND: Cardiac arrhythmias and sleep-disordered breathing (SDB) are common comorbidities in heart failure with reduced ejection fraction (HFrEF). However, understanding of the association between arrhythmias and SDB is poor. This study assessed the occurrence and circadian distribution of ventricular arrhythmias in HFrEF patients with and without SDB. METHODS: This retrospective analysis included HFrEF patients admitted for unattended overnight cardiorespiratory polygraphy and 24-h Holter-ECG recording...
May 8, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29735633/atrial-fibrillation-detection-during-24-hour-ambulatory-blood-pressure-monitoring-comparison-with-24-hour-electrocardiography
#8
Anastasios Kollias, Antonios Destounis, Petros Kalogeropoulos, Konstantinos G Kyriakoulis, Angeliki Ntineri, George S Stergiou
This study assessed the diagnostic accuracy of a novel 24-hour ambulatory blood pressure (ABP) monitor (Microlife WatchBP O3 Afib) with implemented algorithm for automated atrial fibrillation (AF) detection during each ABP measurement. One hundred subjects (mean age 70.6±8.2 [SD] years; men 53%; hypertensives 85%; 17 with permanent AF; 4 paroxysmal AF; and 79 non-AF) had simultaneous 24-hour ABP monitoring and 24-hour Holter monitoring. Among a total of 6410 valid ABP readings, 1091 (17%) were taken in ECG AF rhythm...
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29731788/the-first-case-of-the-reveal-linq%C3%A2-insertable-cardiac-monitor-implanted-in-a-child-in-malta
#9
A Aquilina, O Aquilina, M Sammut, V Grech
Background: The Reveal LINQ™Insertable Cardiac Monitor (ICM) or Implantable Loop recorder (ILR), is a miniaturized, subcutaneous, single lead, electrocardiographic monitoring device which has been extensively used in the differential diagnosis of unexplained syncope and palpitations in adults. Patient Description: We describe an asymptomatic 20-month-old boy, noted to have incidental bradycardia on routine examination and in whom Holter monitoring revealed complete heart block (CHB)...
October 2017: Images in Paediatric Cardiology
https://www.readbyqxmd.com/read/29724227/mobile-gpu-based-implementation-of-automatic-analysis-method-for-long-term-ecg
#10
Xiaomao Fan, Qihang Yao, Ye Li, Runge Chen, Yunpeng Cai
BACKGROUND: Long-term electrocardiogram (ECG) is one of the important diagnostic assistant approaches in capturing intermittent cardiac arrhythmias. Combination of miniaturized wearable holters and healthcare platforms enable people to have their cardiac condition monitored at home. The high computational burden created by concurrent processing of numerous holter data poses a serious challenge to the healthcare platform. An alternative solution is to shift the analysis tasks from healthcare platforms to the mobile computing devices...
May 3, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29723990/on-the-beat-detection-performance-in-long-term-ecg-monitoring-scenarios
#11
Francisco-Manuel Melgarejo-Meseguer, Estrella Everss-Villalba, Francisco-Javier Gimeno-Blanes, Manuel Blanco-Velasco, Zaida Molins-Bordallo, José-Antonio Flores-Yepes, José-Luis Rojo-Álvarez, Arcadi García-Alberola
Despite the wide literature on R-wave detection algorithms for ECG Holter recordings, the long-term monitoring applications are bringing new requirements, and it is not clear that the existing methods can be straightforwardly used in those scenarios. Our aim in this work was twofold: First, we scrutinized the scope and limitations of existing methods for Holter monitoring when moving to long-term monitoring; Second, we proposed and benchmarked a beat detection method with adequate accuracy and usefulness in long-term scenarios...
May 1, 2018: Sensors
https://www.readbyqxmd.com/read/29721503/radiofrequency-versus-cryoballoon-ablation-of-atrial-fibrillation-an-evaluation-using-ecg-holter-monitoring-and-implantable-loop-recorders-to-monitor-absolute-and-clinical-effectiveness
#12
Karapet Davtyan, Victoria Shatakhtsyan, Hermine Poghosyan, Alexandr Deev, Alexey Tarasov, Maria Kharlap, Svetlana Serdyuk, Georgy Simonyan, Sergey Boytcov
Introduction: While several studies have compared the radiofrequency current (RFC) and cryoablation for the treatment of patients with atrial fibrillation (AF), no study has monitored the long-term outcomes with the usage of implantable loop recorders (ILRs). Methods: We enrolled 89 consecutive patients with nonvalvular paroxysmal AF ( N = 44 for RFC and N = 45 for cryoballoon). The primary efficacy end point was the assessment of effectiveness for each group (RFC versus cryoballoon) when examining freedom from arrhythmia by monitoring with ECG, Holter, and implantable loop recoder (ILR)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29704608/comparison-of-one-and-three-lead-ecg-to-measure-cardiac-intervals-and-differentiate-drug-induced-multi-channel-block
#13
Robert Brockway, Marina Brockway, Brian Brockway, Robert Hamlin
INTRODUCTION: FDA has established initiatives to characterize clinical and non-clinical biomarkers to enable more precise prediction of proarrhythmia risk based upon knowledge of drug effect on multiple cardiac ion channels (Colatsky et al., 2016). The FDA has recently demonstrated superiority of early ventricular repolarization interval (JTp) in differentiating pure hERG block from multi-channel block in human subjects. Preclinical studies often acquire a single lead ECG, whereas FDA measurements of JTp were derived ​from a spatial vectorcardiogram computed using multiple leads...
April 25, 2018: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29703518/the-safira-study-a-reflection-on-the-prevalence-and-treatment-patterns-of-atrial-fibrillation-and-cardiovascular-risk-factors-in-7500-elderly-subjects
#14
Pedro Monteiro
INTRODUCTION AND AIM: Atrial fibrillation (AF) is a common arrhythmia and an important risk factor for ischemic stroke. The current ESC guidelines state that all patients aged 65 and over should be regularly screened for AF. The SAFIRA study aimed to determine the prevalence, epidemiology and clinical and therapeutic characterization of AF in the Portuguese elderly population. METHODS: The study population (7500 subjects) were recruited from all Portuguese administrative regions...
April 24, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29681953/omega-3-fatty-acid-supplementation-improves-heart-rate-variability-in-obese-children
#15
Christoph Baumann, Ulla Rakowski, Reiner Buchhorn
Obese children and adolescents are at high risk of developing cardiovascular diseases later in life. We hypothesized that cardiovascular prophylaxis with omega-3 fatty acids could benefit them. In our study, 20 children and adolescents (mean body mass index percentile: 99.1; mean age: 11.0 years) underwent two ambulatory 24 h Holter electrocardiography (ECG) recordings (before and after at least 3 months of omega-3 fatty acid supplementation). Time domain heart rate variability (HRV) and heart rate (HR) were examined for these patients...
2018: International Journal of Pediatrics
https://www.readbyqxmd.com/read/29680382/phenotypic-description-of-cardiac-findings-in-a-population-of-dogue-de-bordeaux-with-an-emphasis-on-atrial-fibrillation
#16
G McAulay, K Borgeat, J Sargent, P Mõtsküla, J Neves, J Dukes-McEwan, V Luis Fuentes
The aim of this study was to describe the clinical phenotype of Dogue de Bordeaux (DdB) referred for cardiac investigation, with particular reference to the prevalence of atrial fibrillation and associated features. Review of canine medical records of two United Kingdom veterinary referral hospitals identified 64 DdB with available echocardiographic and electrocardiographic (ECG)/Holter data. Atrial fibrillation was documented in 25 (39%) dogs and supraventricular tachycardia was recorded in five (7.8%) dogs...
April 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29672694/successful-surgical-ablation-of-atrial-fibrillation-does-not-disturb-long-term-sinus-rhythm-variability
#17
Grzegorz Suwalski, Piotr Suwalski
OBJECTIVES: Surgical ablation of atrial fibrillation (AF) aims to restore normal sinus rhythm while protecting the sinus node from surgical damage. Surgical lesions may affect autonomic neural structures and influence physiological heart rate variability (HRV). The primary aim of this study was to describe long-term dynamics of HRV after successful surgical ablation of AF. The secondary aim was to compare sinus node function after successful ablation of AF with either left atrial modified Maze procedure or epicardial pulmonary vein isolation after long-term follow-up...
April 16, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29667277/arrhythmic-manifestation-of-peripartum-cardiomyopathy-case-report
#18
Patryk Siedlecki, Małgorzata Kurpesa, Barbara Uznańska-Loch, Ewa Trzos, Jarosław Damian Kasprzak
We report a case of 26-year-old woman, with arrhythmic manifestation of peripartum cardiomyopathy with moderate heart failure. Ventricular arrhythmia recorded in ambulatory Holter ECG (premature ventricular contractions) was most severe during pregnancy, reduced when beta-blocker therapy was initiated and almost completely resolved after delivery. Then, 1 year after hospitalization in Cardiology Department, recurrence was observed with recorded short episode of nonsustained ventricular tachycardia.
April 17, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29657588/portable-out-of-hospital-electrocardiography-a-review-of-current-technologies
#19
REVIEW
Agam Bansal, Rajnish Joshi
Background: Availability of portable and home-based electrocardiography (ECG) is an important medical innovation, which has a potential to transform medical care. We performed this review to understand the current state of out-of-hospital portable ECG technologies with respect to their scope, ease of use, data transmission capabilities, and diagnostic accuracy. Methods: We conducted PubMed and Internet searches for "handheld" or "wearable" or "patch" electrocardiography devices to enlist available technologies...
April 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29652902/relations-between-right-ventricular-morphology-and-clinical-electrical-and-genetic-parameters-in-brugada-syndrome
#20
Belinda Gray, Ganesh Kumar Gnanappa, Richard D Bagnall, Giuseppe Femia, Laura Yeates, Jodie Ingles, Charlotte Burns, Rajesh Puranik, Stuart M Grieve, Christopher Semsarian, Raymond W Sy
BACKGROUND: Increasing evidence suggests the presence of structural changes affecting the right ventricular outflow tract (RVOT) in patients with Brugada Syndrome (BrS). The aim of this study was to characterise the RV morphology in BrS and explore associations between morphologic, clinical, electrical, and genetic parameters using non-invasive multimodality testing. METHODS: Consecutive BrS patients (recruited 2013-2015) underwent clinical assessment, dedicated RV imaging using cardiac magnetic resonance (CMR) imaging (unless contra-indicated), electrical assessment (electrocardiogram, Holter monitoring, signal-averaged ECG[SAECG]) and genotyping...
2018: PloS One
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