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https://www.readbyqxmd.com/read/28283324/early-mobilization-why-what-for-and-how
#1
A R Miranda Rocha, B P Martinez, V Z Maldaner da Silva, L A Forgiarini Junior
Early mobilization strategies in the intensive care unit may result in the prevention and reduction of polyneuromyopathy in the critical patient, improved quality of life, shortened ICU and hospital stay, and lesser mortality during hospitalization. However, it is well known that factors such as the protocol used, the population included in the studies, the timing of the strategy, the severity of the patients and different barriers directly influence the outcomes. This study examines the main protocols described in the literature and their associated results...
March 7, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28255448/effects-of-different-early-rehabilitation-techniques-on-haemodynamic-and-metabolic-parameters-in-sedated-patients-protocol-for-a-randomised-single-bind-cross-over-trial
#2
Clément Medrinal, Yann Combret, Guillaume Prieur, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Éric Frenoy, Olivier Contal, Bouchra Lamia
INTRODUCTION: Early rehabilitation has become widespread practice for patients in intensive care; however, the prevalence of intensive care unit-acquired weakness remains high and the majority of physiotherapy is carried out in bed. Several inbed rehabilitation methods exist, but we hypothesise that techniques that provoke muscle contractions are more effective than passive techniques. METHODS: A randomised, controlled cross-over study will be carried out to evaluate and compare the effectiveness of early rehabilitation techniques on cardiac output (CO) in sedated patients in intensive care...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28243999/physiological-effects-of-early-incremental-mobilization-of-a-patient-with-acute-intracerebral-and-intraventricular-hemorrhage-requiring-dual-external-ventricular-drainage
#3
Sowmya Kumble, Elizabeth K Zink, Mackenzie Burch, Sandra Deluzio, Robert D Stevens, Mona N Bahouth
BACKGROUND: Recent trials have challenged the notion that very early mobility benefits patients with acute stroke. It is unclear how cerebral autoregulatory impairments, prevalent in this population, could be affected by mobilization. The safety of mobilizing patients who have external ventricular drainage (EVD) devices for cerebrospinal fluid diversion and intracranial pressure (ICP) monitoring is another concern due to risk of device dislodgment and potential elevation in ICP. We report hemodynamic and ICP responses during progressive, device-assisted mobility interventions performed in a critically ill patient with intracerebral hemorrhage (ICH) requiring two EVDs...
February 27, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28193264/the-clinical-picture-of-cachexia-a-mosaic-of-different-parameters-experience-of-503-patients
#4
S Schwarz, O Prokopchuk, K Esefeld, S Gröschel, J Bachmann, S Lorenzen, H Friess, M Halle, M E Martignoni
BACKGROUND: Despite our growing knowledge about the pathomechanisms of cancer cachexia, a whole clinical picture of the cachectic patient is still missing. Our objective was to evaluate the clinical characteristics in cancer patients with and without cachexia to get the whole picture of a cachectic patient. METHODS: Cancer patients of the University Clinic "Klinikum rechts der Isar" with gastrointestinal, gynecological, hematopoietic, lung and some other tumors were offered the possibility to take part in the treatment concept including a nutrition intervention and an individual training program according to their capability...
February 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28188010/the-1-min-sit-to-stand-test-in-cystic-fibrosis-insights-into-cardiorespiratory-responses
#5
Thomas Radtke, Helge Hebestreit, Milo A Puhan, Susi Kriemler
BACKGROUND: We aimed to characterize the cardiopulmonary response during a 1-min sit-to-stand (STS) test and compare peak exercise cardiorespiratory variables to a maximal cardiopulmonary exercise test (CPET) in cystic fibrosis (CF). We further aimed to assess the validity of the STS power index (PowerSTS) as a measure of exercise capacity. METHODS: Fifteen adult CF patients performed spirometry, CPET and the 1-min STS test with respiratory gas analysis. RESULTS: Peak-exercise cardiorespiratory variables during the 1-min STS test correlated strongly (r=0...
February 7, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28166120/pulmonary-artery-wedge-pressure-relative-to-exercise-workrate-in-older-men-and-women
#6
Sam Esfandiari, Stephen P Wright, Jack M Goodman, Zion Sasson, Susanna Mak
PURPOSE: An augmented pulmonary artery wedge pressure (PAWP) response may explain exercise intolerance in some humans. However, routine use of exercise hemodynamic testing is limited by a lack of data from normal older men and women. Our objective was to evaluate the exercise PAWP response and the potential for sexual dimorphism in healthy, non-dyspneic older adults. METHODS: Thirty-six healthy volunteers [18 men (54±7 years)/18 women (58±6 years)] were studied at rest (Control) and during two stages of semi-upright cycle-ergometry, at heart rates of 100 bpm (Light Exercise) and 120 bpm (Moderate Exercise)...
February 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28101567/influence-of-arm-crank-ergometry-on-development-of-lymphedema-in-breast-cancer-patients-after-axillary-dissection-a-randomized-controlled-trail
#7
RANDOMIZED CONTROLLED TRIAL
Thorsten Schmidt, Jette Berner, Walter Jonat, Burkhard Weisser, Christioph Röcken, Marion van Mackelenbergh, Christoph Mundhenke
OBJECTIVE: To investigate the safety and efficacy of arm crank ergometry in breast cancer patients after axillary lymph node dissection, with regard to changes in bioelectrical impedance analysis, arm circumference, muscular strength, quality of life and fatigue. DESIGN: Randomized controlled clinical intervention trial. SUBJECTS: Forty-nine patients with breast cancer after axillary lymph node dissection. METHODS: Arm crank ergometer training twice-weekly was compared with usual care over 12 weeks...
January 19, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28035016/esmolol-infusion-versus-propranolol-infusion-effects-on-heart-rate-and-blood-pressure-in-healthy-volunteers
#8
Matthew D Muller, Tariq Ali Ahmad, Alvaro F Vargas Pelaez, David N Proctor, Anthony S Bonavia, J Carter Luck, Stephan R Maman, Amanda J Ross, Urs A Leuenberger, Patrick M McQuillan
Despite its widespread clinical use, the β1-adrenergic receptor antagonist esmolol hydrochloride is not commonly used in human physiology research, and the effective dose of esmolol (compared with the nonselective β-blocker propranolol) is unclear. In four separate studies we used cycle ergometry exercise and infusions of isoproterenol and epinephrine to test the heart rate (HR)-lowering effect of esmolol compared with propranolol and saline in healthy humans. In cohort 1, both esmolol (ΔHR 57 ± 6 beats/min) and propranolol (ΔHR 56 ± 7 beats/min) attenuated exercise tachycardia compared with saline (ΔHR 88 ± 17 beats/min)...
March 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28025662/the-effect-of-a-live-high-train-high-exercise-regimen-on-behavioural-temperature-regulation
#9
Shawnda A Morrison, Urša Ciuha, Daniela Zavec-Pavlinić, Ola Eiken, Igor B Mekjavic
PURPOSE: Acute hypoxia alters the threshold for sensation of cutaneous thermal stimuli. We hypothesised that hypoxia-induced alterations in cutaneous temperature sensation may lead to modulation of the perception of temperature, ultimately influencing behavioural thermoregulation and that the magnitude of this effect could be influenced by daily physical training. METHODS: Fourteen men were confined 10 days to a normobaric hypoxic environment (PIO2 = 88.2 ± 0...
December 26, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28009787/prevalence-of-exercise-induced-arterial-hypoxemia-in-distance-runners-at-sea-level
#10
Keren Constantini, David A Tanner, Timothy P Gavin, Craig A Harms, Joel M Stager, Robert F Chapman
PURPOSE: It has been reported that ~50% of endurance-trained men demonstrate exercise induced arterial oxyhemoglobin hypoxemia (EIAH) during heavy exercise. However, this often-cited prevalence rate comes from a single study using a cohort of 25 highly trained men who completed maximal cycle ergometry. As arterial oxyhemoglobin saturation (SpO2) during maximal exercise is reported to be significantly lower during treadmill vs. cycle ergometry in the same subjects, we hypothesized that the prevalence of EIAH would be greater than previously reported (and commonly referenced) in a larger cohort of highly endurance-trained men during maximal treadmill running...
December 22, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27997623/the-coupling-of-peripheral-blood-pressure-and-ventilatory-responses-during-exercise-in-young-adults-with-cystic-fibrosis
#11
Erik H Van Iterson, Courtney M Wheatley, Sarah E Baker, Thomas P Olson, Wayne J Morgan, Eric M Snyder
PURPOSE: Cystic fibrosis (CF) is commonly recognized as a pulmonary disease associated with reduced airway function. Another primary symptom of CF is low exercise capacity where ventilation and gas-exchange are exacerbated. However, an independent link between pathophysiology of the pulmonary system and abnormal ventilatory and gas-exchange responses during cardiopulmonary exercise testing (CPET) has not been established in CF. Complicating this understanding, accumulating evidence suggests CF demonstrate abnormal peripheral vascular function; although, the clinical implications are unclear...
2016: PloS One
https://www.readbyqxmd.com/read/27993287/addition-of-vitamin-b12-to-exercise-training-improves-cycle-ergometer-endurance-in-advanced-copd-patients-a-randomized-and-controlled-study
#12
Fernanda Viana Paulin, Alessandro Moura Zagatto, Gaspar R Chiappa, Paulo de Tarso Müller
Vitamin B12 is essential in the homocysteine, mitochondrial, muscle and hematopoietic metabolisms, and its effects on exercise tolerance and kinetics adjustments of oxygen consumption (V'O2p) in rest-to-exercise transition in COPD patients are unknown. This randomized, double-blind, controlled study aimed to verify a possible interaction between vitamin B12 supplementation and these outcomes. After recruiting 69 patients, 35 subjects with moderate-to-severe COPD were eligible and 32 patients concluded the study, divided into four groups (n = 8 for each group): 1...
January 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/27992070/exercise-for-haemophilia
#13
REVIEW
Karen Strike, Kathy Mulder, Rojer Michael
BACKGROUND: Haemophilia is a bleeding disorder associated with haemorrhaging into joints and muscles. Exercise is often used to aid recovery after bleeds, and to improve joint function in the presence of arthropathy. OBJECTIVES: Our objective was to systematically review the available evidence on the safety and effectiveness of exercise for people with haemophilia. SEARCH METHODS: We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Coagulopathies Trials Register and electronic databases PubMed, OVID-Embase, and CINAHL...
December 19, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27938891/reference-standards-for-cardiorespiratory-fitness-measured-with-cardiopulmonary-exercise-testing-using-cycle-ergometry-data-from-the-fitness-registry-and-the-importance-of-exercise-national-database-friend-registry
#14
Leonard A Kaminsky, Mary T Imboden, Ross Arena, Jonathan Myers
The importance of cardiorespiratory fitness (CRF) is well established. This report provides newly developed standards for CRF reference values derived from cardiopulmonary exercise testing (CPX) using cycle ergometry in the United States. Ten laboratories in the United States experienced in CPX administration with established quality control procedures contributed to the "Fitness Registry and the Importance of Exercise: A National Database" (FRIEND) Registry from April 2014 through May 2016. Data from 4494 maximal (respiratory exchange ratio, ≥1...
February 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27931056/-guideline-s2k-awmf-of-the-deutsche-gesellschaft-f%C3%A3-r-pneumologie-und-beatmungsmedizin-and-the-deutsche-gesellschaft-f%C3%A3-r-arbeitsmedizin-und-umweltmedizin-diagnostics-and-expert-opinion-in-the-occupational-disease-no-4101-silicosis-including-coal-worker-s-pneumoconiosis
#15
X Baur, M Heger, R M Bohle, K G Hering, K Hofmann-Preiß, D Nowak, A Tannapfel, H Teschler, T Voshaar, T Kraus
During the last 1.5 years an update of the guideline on silicosis was made by an interdisciplinary working group. New medical and scientific knowledge and the experience in expert opinion practice were taken into account.By preparing the initial guideline in 2010 standardization of diagnostics and adaption of the "Moers convention" which was not based on medical knowledge was in the focus, whereas the current update deals with fine emendation and extension, especially of the compensation rate (adaption with the Reichenhall recommendation)...
December 2016: Pneumologie
https://www.readbyqxmd.com/read/27927683/pharmacokinetics-and-pharmacodynamics-of-inorganic-nitrate-in-heart-failure-with-preserved-ejection-fraction
#16
Payman Zamani, Victor X Tan, Haideliza Soto-Calderon, Melissa Beraun, Jeffrey Brandimarto, Lien Trieu, Swapna Varakantam, Paschalis-Thomas Doulias, Raymond R Townsend, Jesse Chittams, Kenneth B Margulies, Thomas P Cappola, David C Poole, Harry Ischiropoulos, Julio A Chirinos
RATIONALE: Nitrate-rich beetroot juice has been shown to improve exercise capacity in Heart Failure with Preserved Ejection Fraction (HFpEF), but studies using pharmacologic preparations of inorganic nitrate are lacking. OBJECTIVE: To determine: (1) the dose-response effect of potassium nitrate (KNO3) on exercise capacity; (2) the population-specific pharmacokinetic and safety profile of KNO3 in HFpEF. METHODS AND RESULTS: We randomized 12 subjects with HFpEF to oral KNO3 (n=9) or potassium chloride (KCl, n=3)...
December 7, 2016: Circulation Research
https://www.readbyqxmd.com/read/27925037/nutrition-assessment-modal-ergometry
#17
D F Ribas, G Kelman, R F Buzzini, R S Simões, W M Bernardo
No abstract text is available yet for this article.
October 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27884959/cardiac-responses-to-exercise-distinguish-postural-orthostatic-tachycardia-syndrome-variants
#18
Paolo T Pianosi, Darrell R Schroeder, Philip R Fischer
We previously showed that one-third of adolescents with postural orthostatic tachycardia syndrome (POTS) have hyperkinetic circulation. In a subsequent cohort, we compare participants with POTS grouped according to cardiac output (Q˙) versus oxygen uptake (V˙O2) function, whose circulatory response to exercise lay at the lower end of this distribution. We hypothesized that such grouping determines the circulatory response to incremental-protocol, upright, cycle ergometry by whatever blend of flow and resistance adjustments best maintains normal blood pressure...
November 2016: Physiological Reports
https://www.readbyqxmd.com/read/27858577/long-term-endurance-training-increases-serum-cathepsin-s-and-decreases-il-6-and-hscrp-levels
#19
Michael Sponder, Ioana-Alexandra Campean, Michael Emich, Monika Fritzer-Szekeres, Brigitte Litschauer, Jutta Bergler-Klein, Senta Graf, Jeanette Strametz-Juranek
Cathepsin S (CS) was shown to play a key role in cancer progression, atherosclerosis, heart valve disease, insulin resistance and diabetes mellitus. The present prospective study aimed to investigate the influence of sports on CS, interleukin-6 (Il-6) and high-sensitivity C-reactive protein (hsCRP) levels. Ninety-eight of 109 participants completed the study. Ergometries were performed at baseline and after 8 months to evaluate/quantify the performance gain. Blood samples were taken at baseline and every 2 months...
November 18, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27857959/head-temperature-modulates-thermal-behavior-in-the-cold-in-humans
#20
Toby Mündel, Aaron Raman, Zachary J Schlader
We tested the hypothesis that skin temperature, specifically of the head, is capable of modulating thermal behavior during exercise in the cold. Following familiarization 8 young, healthy, recreationally active males completed 3 trials, each consisting of 30 minutes of self-paced cycle ergometry in 6°C. Participants were instructed to control their exercise work rate to achieve and maintain thermal comfort. On one occasion participants wore only shorts and shoes (Control) and on the 2 other occasions their head was either warmed (Warming) or cooled (Cooling)...
April 2016: Temperature: Multidisciplinary Biomedical Journal
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