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Christine A E Eenhorst, Kamil G Laban, Roos J Leguit, Timothy R D J Radstake, Rachel Kalmann
No abstract text is available yet for this article.
December 2017: Acta Ophthalmologica
Ward R Bijlsma, Fleur C Van 't Hullenaar, Maarten P Mourits, Rachel Kalmann
PURPOSE: To systematically analyze existing classification systems for idiopathic orbital inflammation (IOI) and propose and test a new best practice classification system. METHODS: A systematic literature search was conducted to find all studies that described and applied a classification system for IOI. Classification categories used in more than two studies were extracted, and criteria for these categories were defined using common descriptors. Using patient data, these newly defined classification systems were evaluated...
August 2012: Orbit
Ward R Bijlsma, Niels J Elbert, Rachel Kalmann
PURPOSE: To provide a framework when to biopsy patients suspected of idiopathic orbital inflammation (IOI). MATERIALS AND METHODS: One-hundred seventeen patients were selected with signs of orbital inflammation in whom after history and physical examination, no definite diagnosis was made. In this cohort, the role of biopsy in making a diagnosis was evaluated and compared to a therapeutic trial of corticosteroids. RESULTS: In 67 of 117 patients, a diagnosis was evident after imaging and laboratory testing...
March 2012: Current Eye Research
Ward R Bijlsma, Ronald J Hené, Maarten P Mourits, Rachel Kalmann
OBJECTIVES: Orbital manifestation of Wegener's granulomatosis is diverse and diagnosis is often difficult. This study aims to improve the diagnostic strategy in orbital Wegener. METHODS: A review of the diagnostic process in patients in whom a diagnosis of orbital WG was considered. RESULTS: Thirty-three patients were analysed, consisting of 15 patients with orbital WG, 11 with idiopathic orbital inflammation, 6 with orbital sarcoidosis and one with aspergillosis...
January 2011: Clinical and Experimental Rheumatology
Ward R Bijlsma, Dion Paridaens, Rachel Kalmann
BACKGROUND: Prednisone pulse therapy is used to treat active non-infectious orbital inflammatory disease to attain faster clinical improvement and to shorten the duration of prednisone treatment. This study addresses the use of intravenous methylprednisolone (IVMP) pulse therapy, in addition to oral prednisone (OP), in the treatment of severe idiopathic orbital inflammation (IOI). METHODS: This was a multicentre retrospective cohort study. Patients with severe IOI treated with IVMP pulse and OP therapy (IVMP+OP) were compared with patients with IOI who were treated only with OP...
August 2011: British Journal of Ophthalmology
Ward R Bijlsma, Carla H van Gils, Dion Paridaens, Maarten P Mourits, Rachel Kalmann
OBJECTIVE: To identify risk factors involved in the development of idiopathic orbital inflammation (IOI). METHODS: Case-control study of 69 adults who had had a first episode of IOI and 296 adult controls with rhegmatogenous retinal detachment (RD) selected from three orbital centres in The Netherlands between 2000 and 2006. Participants filled out a questionnaire on demographic factors, medical history, health status and exposures for the 2 years prior to disease presentation...
March 2011: British Journal of Ophthalmology
Ward R Bijlsma, Rachel Kalmann
No abstract text is available yet for this article.
January 2010: Archives of Ophthalmology
J De Hoog, S Stravers, R Kalmann
PURPOSE: To identify the predictive factors for overcorrection and depression impairment after recession of the inferior rectus muscle (IRM) in patients with Graves' orbitopathy. DESIGN: Retrospective cohort study, single institution. METHODS: The charts of 124 consecutive patients who underwent recession of the IRM were retrospectively examined, as well as all literature with regard to the subject until January 2008. Ductions measurements, computed tomography (CT) appearance, proptosis, NOSPECS-scores, duration of thyroid disease, duration of orbitopathy, previous treatment of Graves' thyroid disease and orbitopathy, extent of recession, age, gender, diabetes, smoking, and use of immunosuppressants were all evaluated for prognostic significance...
June 2010: Eye
, M P Mourits, H Bijl, M A Altea, L Baldeschi, K Boboridis, N Currò, A J Dickinson, A Eckstein, M Freidel, C Guastella, G J Kahaly, R Kalmann, G E Krassas, C M Lane, J Lareida, C Marcocci, M Marino, M Nardi, Ch Mohr, C Neoh, A Pinchera, J Orgiazzi, S Pitz, P Saeed, M Salvi, S Sellari-Franceschini, M Stahl, G von Arx, W M Wiersinga
AIM: To compare the outcome of various surgical approaches of orbital decompression in patients with Graves' orbitopathy (GO) receiving surgery for disfiguring proptosis. METHOD: Data forms and questionnaires from consecutive, euthyroid patients with inactive GO who had undergone orbital decompression for disfiguring proptosis in 11 European centres were analysed. RESULTS: Eighteen different (combinations of) approaches were used, the swinging eyelid approach being the most popular followed by the coronal and transconjunctival approaches...
November 2009: British Journal of Ophthalmology
Rob J van Geest, Inna V Sasim, Hans P F Koppeschaar, Rachel Kalmann, Simone N Stravers, Ward R Bijlsma, Maarten P Mourits
OBJECTIVE: To assess whether methylprednisolone (MP) pulse therapy is efficacious in the treatment of moderately severe Graves' orbitopathy (GO). DESIGN: Prospective, placebo (PL)-controlled, double-blind, randomized study. METHODS: Fifteen previously untreated patients with active, moderately severe GO participated in the study; 6 patients received MP and 9 patients a PL. Moderately severe disease was defined using the NOSPECS classification of clinical signs of GO ...
February 2008: European Journal of Endocrinology
M Ufuk Aluclu, Selen Bahceci, Mithat Bahceci
BACKGROUND & AIM: Dandy-Walker malformation, a rare congenital brain malformation, is described as a triad of cystic dilatation of the fourth ventricle, complete or partial agenesis of the cerebellar vermis, and an enlarged posterior fossa with elevated tentorium. We aimed to report an association of Kallmann's syndrome and Dandy-Walker malformation. CASE: A fifteen years old boy was referred to endocrinology department due to delayed puberty. Stages of male genital development according to Marshall and Tanner, was stage G1 and P1 respectively...
June 2007: Neuro Endocrinology Letters
Inna V Sasim, Mieke E L de Graaf, Tos T J M Berendschot, Rachel Kalmann, Chantal van Isterdael, Maarten P Mourits
PURPOSE: To compare 2 different approaches for 3-wall orbital decompression in patients with disfiguring proptosis due to Graves' orbitopathy, and to determine which technique is preferable. DESIGN: Retrospective nonrandomized study with a concurrent comparison group. PARTICIPANTS: Charts of 74 consecutive patients with disfiguring proptosis due to Graves' orbitopathy who underwent coronal (46) or swinging eyelid (28) decompression between January 1, 2000 and January 1, 2004 were studied retrospectively...
July 2005: Ophthalmology
Maarten Ph Mourits, Rachel Kalmann, Inna V. Sasim
purpose 1) To test the short- and long-term efficacy of Methylprednisolone Pulse Therapy (MPT) for patients with Dysthyroid Optic Neuropathy (DON). 2) To assess possible side-effects of MPT. 3) To assess whether a delay in decompressive surgery would influence the visual outcome. study design Retrospective, uncontrolled. method The records of 62 consecutive patients with DON, who received MPT between 1994 and 2000, were evaluated with special attention for pre- and post treatment ophthalmic and orthoptic parameters, Clinical Activity Score (CAS), visual fields and visual evoked potentials, and treatment complications...
December 2001: Orbit
Rachel Kalmann, Maarten P Mourits
PURPOSE: To report a case of late recurrence of unilateral Graves orbitopathy on the contralateral side after 7 years. DESIGN: Interventional case report. METHODS: A 44-year-old woman with left unilateral Graves orbitopathy underwent two-wall orbital decompression on the left side. After strabismus surgery and left upper eyelid surgery, she was discharged. RESULTS: Seven years after discharge, the patient developed Graves orbitopathy on the right side, and she underwent two-wall orbital decompression on the right side...
May 2002: American Journal of Ophthalmology
Michael D Abràmoff, Rachel Kalmann, Mieke E L de Graaf, Jan S Stilma, Maarten P Mourits
PURPOSE: To study possible causes of motility disturbances that may result from orbital decompression surgery in patients with Graves orbitopathy and especially the role of rectus extraocular muscle paths. METHODS: Sixteen patients with Graves orbitopathy were studied before and 3 to 6 months after translid (6 patients) and coronal (10 patients) orbital decompression surgery for disfiguring proptosis. Ocular motility changes were measured by comparing maximum ductions and severity of diplopia, and the positions and the displacements of the anterior rectus muscle paths were objectively measured using cine magnetic resonance imaging (MRI)...
February 2002: Investigative Ophthalmology & Visual Science
C B Terwee, F W Dekker, M P Mourits, M N Gerding, L Baldeschi, R Kalmann, M F Prummel, W M Wiersinga
OBJECTIVE: The Graves' ophthalmopathy quality of life questionnaire (GO-QOL) is the first instrument available to measure health-related quality of life (HRQL) of patients with Graves' ophthalmopathy. The main objective of this study was to define a minimal clinically important difference (MCID) in score on the GO-QOL that can be considered an important improvement in HRQL by examining changes in GO-QOL scores in patients who subjectively report improvement from their treatment. A secondary objective was to test the longitudinal validity of the GO-QOL, using prespecified hypotheses about expected treatment effects...
March 2001: Clinical Endocrinology
R Kalmann, M P Mourits
AIMS: To assess the prevalence of dysthyroid optic neuropathy (DON) in patients with diabetes mellitus (DM) and Graves' orbitopathy (GO) and to investigate the complications of surgery for GO in these patients. METHODS: The records of 482 consecutive patients with GO referred in a 5 year period were studied. Those patients who also had DM were selected for further study. The prevalence of insulin dependent diabetes mellitus (IDDM) and non-insulin dependent diabetes mellitus (NIDDM) was registered, as well as the prevalence and course of DON...
April 1999: British Journal of Ophthalmology
R Kalmann, M P Mourits
AIMS: To investigate the prevalence and to discuss the necessity of treating elevated intraocular pressures (IOP) in patients with Graves' orbitopathy (GO). In addition, to study the effects of orbital decompression and extraocular muscle surgery on IOP. METHODS: The records of consecutive patients with GO referred in a 5 year period were studied and those selected, in which glaucoma medication had been prescribed, or a diagnosis of primary open angle glaucoma (POAG) or of ocular hypertension (> or = 22 mm Hg) (OH) had been made...
July 1998: British Journal of Ophthalmology
M N Gerding, M F Prummel, R Kalmann, L Koornneef, W M Wiersinga
There is a need for more reliable and validated methods to assess the eye changes in Graves' disease. Such measurements are now available for the assessment of proptosis, eye muscle dysfunction, and optic nerve involvement. However, no validated objective measurement exists for NO SPECS class II signs. The present study compares the use of colour slides with clinical grading for assessing soft-tissue involvement. Forty-three patients were treated with retrobulbar irradiation. Pre-treatment, and 6 months post-treatment the severity of class II signs was graded from 0 to grade c in two ways; 1) Clinically, by two independent, experienced observers, who recorded their scores on the same day; 2) From colour slides, taken at the same visits, which were graded afterwards in one session independently by the same observers...
July 1998: Journal of Endocrinological Investigation
R Kalmann, M P Mourits, J P van der Pol, L Koornneef
AIMS: To determine the effectiveness and safety of three wall orbital decompression by the coronal approach in Graves' ophthalmopathy. METHODS: The records of 125 patients with Graves' ophthalmopathy, who had undergone three wall orbital decompression by coronal approach between April 1984 and October 1993, were studied retrospectively. Special attention was paid to proptosis reduction, changes in ocular motility, and complications. RESULTS: The preoperative Hertel values ranged from 15 to 30 mm (mean 22...
January 1997: British Journal of Ophthalmology
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