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https://www.readbyqxmd.com/read/28432320/formation-of-cuo-nano-flowered-surfaces-via-submerged-photo-synthesis-of-crystallites-and-their-antimicrobial-activity
#1
Fumika Nishino, Melbert Jeem, Lihua Zhang, Kazumasa Okamoto, Satoshi Okabe, Seiichi Watanabe
We report the fabrication of flower-like CuO nanostructured surfaces via submerged photo-synthesis of crystallites (SPSC), which requires only UV illumination in neutral water. In this paper, we discuss the reaction mechanism of the photochemical formation of the SPSC-fabricated CuO nanostructures in detail based on surface microstructural analyses and a radiation-chemical consideration with additional gamma-ray irradiation. Since the SPSC method for surface nanostructural fabrication can work at low temperatures at atmospheric pressure without using harmful substances, it is a potential fabrication method for green nanotechnology applications...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28427532/nanotechnology-for-food-packaging-and-food-quality-assessment
#2
Marco Rossi, Daniele Passeri, Alberto Sinibaldi, Mariglen Angjellari, Emanuela Tamburri, Angela Sorbo, Elisabetta Carata, Luciana Dini
Nanotechnology has paved the way to innovative food packaging materials and analytical methods to provide the consumers with healthier food and to reduce the ecological footprint of the whole food chain. Combining antimicrobial and antifouling properties, thermal and mechanical protection, oxygen and moisture barrier, as well as to verify the actual quality of food, e.g., sensors to detect spoilage, bacterial growth, and to monitor incorrect storage conditions, or anticounterfeiting devices in food packages may extend the products shelf life and ensure higher quality of foods...
2017: Advances in Food and Nutrition Research
https://www.readbyqxmd.com/read/28427246/nanotechnology-and-diabetic-wound-healing-a-review
#3
Dinesh Kumar Chellappan, Yap Yenese, Chew Chian Wei, Gaurav Gupta
The incidence of diabetes has been on the rise and the rate of rise since the turn of this century has been phenomenal. One of the various battling issues faced by diabetics all over the globe is the management of diabetic wounds. Currently there are several management strategies to deal with the treatment of diabetic wounds. The conventional methods have several limitations. One of the major limitations is the rate and progression of healing of a diabetic wound when adopting a conventional diabetic wound management therapy...
April 21, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28426988/solar-photocatalytic-application-of-nbo2oh-as-alternative-photocatalyst-for-water-treatment
#4
Luana Márcia Bezerra Batista, Alexsandro Jhones Dos Santos, Djalma Ribeiro da Silva, Ana Paula de Melo Alves, Sergi Garcia-Segura, Carlos Alberto Martínez-Huitle
Water recycling and industrial effluents remediation are a hot topic of research to reduce the environmental impact of the human activity. Persistent organic pollutants are highly recalcitrant compounds with hazardous effects associated to their fate in water bodies. Several novel technologies have been developed during the last decades to deal with this novel contamination. However, the natural sources and idiosyncrasy of each country lead to the potential application of different technologies. In this context, we have focused on the development of phocotalytic treatment of solutions containing dyes using a novel photocatalytic material, the NbO2OH...
April 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28426070/controllable-synthesis-of-ferromagnetic-antiferromagnetic-core-shell-nws-with-tunable-magnetic-properties
#5
M Irfan, C J Wang, U Khan, W J Li, X M Zhang, W J Kong, P Liu, C H Wan, Y W Liu, X F Han
Several nanotechnology applications are based on the promising scheme of highly anisotropic magnetic nanomaterials. Using this idea, we investigated the structure, magnetic properties, and interfacial exchange anisotropy effects of the Ni/Cr2O3 and Fe/Cr2O3 core-shell nanowires (NWs) geometry. A template-based strategy was developed to synthesize Ni (Fe)-Cr2O3 core-shell NWs, which combines a wet-chemical route and electrodeposition within the nanopores of the membranes. Structural determination in correlation with magnetic testing shows that the crystalline Cr2O3-nanoshells (NSs) cause an enhanced exchange bias, providing an extra source of anisotropy that leads to their magnetic stability...
April 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28424455/flow-virometry-analysis-of-envelope-glycoprotein-conformations-on-individual-hiv-virions
#6
Anush Arakelyan, Wendy Fitzgerald, Deborah F King, Paul Rogers, Hannah M Cheeseman, Jean-Charles Grivel, Robin J Shattock, Leonid Margolis
HIV-1 envelope proteins (Envs) play a critical role in HIV infection. In a correct trimeric conformation, Env mediates virus-cell binding and fusion. Malfunctioning of this machinery renders virions incapable of infecting cells. Each HIV-1 virion carries 10-14 Envs, and therefore a defective Env may not necessarily render a HIV virion non-infectious, since other Env on the same virion may still be functional. Alternatively, it is possible that on a given virion either all the spikes are defective or all are functional...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28423273/conformational-dynamics-of-mechanically-compliant-dna-nanostructures-from-coarse-grained-molecular-dynamics-simulations
#7
Ze Shi, Carlos E Castro, Gaurav Arya
Structural DNA nanotechnology, the assembly of rigid 3D structures of complex yet precise geometries, has recently been used to design dynamic, mechanically-compliant nanostructures with tunable equilibrium conformations and conformational distributions. Here we use coarse-grained molecular dynamics simulations to provide in- sights into the conformational dynamics of a set of mechanically compliant DNA nanostructures-DNA hinges that use single-stranded DNA "springs" to tune the equilibrium conformation of a layered double-stranded DNA "joint" connecting two stiff "arms" constructed from DNA helix bundles...
April 19, 2017: ACS Nano
https://www.readbyqxmd.com/read/28422746/integrating-nanohybrid-membranes-of-reduced-graphene-oxide-chitosan-silica-sol-gel-with-fiber-optic-spr-for-caffeine-detection
#8
Ravi Kant, Rana Tabassum, Banshi D Gupta
Caffeine is the most popular psychoactive drug consumed in the world for improving alertness and enhancing wakefulness. However, caffeine consumption beyond limits can result in lot of physiological complications in human beings. In this work, we report a novel detection scheme for caffeine integrating nanohybrid membranes of reduced graphene oxide (rGO) in chitosan modified silica sol gel (rGO: chitosan: silica sol gel) with fiber optic surface plasmon resonance. The chemically synthesized nanohybrid membrane forming the sensing route has been dip coated over silver coated unclad central portion of an optical fiber...
May 12, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28422481/gold-nanoparticles-induced-endothelial-leakiness-depends-on-particle-size-and-endothelial-cell-origin
#9
Magdiel I Setyawati, Chor Yong Tay, Boon Huat Bay, David T Leong
The endothelium presents a formidable barrier for cancer nanomedicine, as the intravenously introduced nanomedicine needs to leave the blood vessel at the tumor site. Endothelial permeability and retention effect (EPR) is not dependable since it is derived from tumors. Certain nanoparticles with specific characteristics are able to induce micrometer sized gaps between endothelial cells. This effect is called "nanoparticle induced endothelial leakiness" (NanoEL). NanoEL therefore allows the nanotechnology to control access to the tumor even in the absence of any EPR effect...
April 20, 2017: ACS Nano
https://www.readbyqxmd.com/read/28422082/molecular-imprinting-of-macromolecules-for-sensor-applications
#10
REVIEW
Yeşeren Saylan, Fatma Yilmaz, Erdoğan Özgür, Ali Derazshamshir, Handan Yavuz, Adil Denizli
Molecular recognition has an important role in numerous living systems. One of the most important molecular recognition methods is molecular imprinting, which allows host compounds to recognize and detect several molecules rapidly, sensitively and selectively. Compared to natural systems, molecular imprinting methods have some important features such as low cost, robustness, high recognition ability and long term durability which allows molecularly imprinted polymers to be used in various biotechnological applications, such as chromatography, drug delivery, nanotechnology, and sensor technology...
April 19, 2017: Sensors
https://www.readbyqxmd.com/read/28421428/how-has-cder-prepared-for-the-nano-revolution-a-review-of-risk-assessment-regulatory-research-and-guidance-activities
#11
Katherine M Tyner, Nan Zheng, Stephanie Choi, Xiaoming Xu, Peng Zou, Wenlei Jiang, Changning Guo, Celia N Cruz
The Nanotechnology Risk Assessment Working Group in the Center for Drug Evaluation and Research (CDER) within the United States Food and Drug Administration (FDA) was established to assess the potential impact of nanotechnology on drug products. One of the working group's major initiatives has been to conduct a comprehensive risk management exercise regarding the potential impact of nanomaterial pharmaceutical ingredients and excipients on drug product quality, safety, and efficacy. This exercise concluded that current review practices and regulatory guidance are capable of detecting and managing the potential risks to quality, safety, and efficacy when a drug product incorporates a nanomaterial...
April 18, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28421100/integrated-approach-of-agri-nanotechnology-challenges-and-future-trends
#12
REVIEW
Sandhya Mishra, Chetan Keswani, P C Abhilash, Leonardo F Fraceto, Harikesh Bahadur Singh
Nanotechnology representing a new frontier in modern agriculture is anticipated to become a major thrust in near future by offering potential applications. This integrating approach, i.e., agri-nanotechnology has great potential to cope with global challenges of food production/security, sustainability and climate change. However, despite the potential benefits of nanotechnology in agriculture so far, their relevance has not reached up to the field conditions. The elevating concerns about fate, transport, bioavailability, nanoparticles toxicity and inappropriateness of regulatory framework limit the complete acceptance and inclination to adopt nanotechnologies in agricultural sector...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28421077/human-scavenger-receptor-a1-mediated-inflammatory-response-to-silica-particle-exposure-is-size-specific
#13
Nobuo Nishijima, Toshiro Hirai, Kazuki Misato, Michihiko Aoyama, Etsushi Kuroda, Ken J Ishii, Kazuma Higashisaka, Yasuo Yoshioka, Yasuo Tsutsumi
The application of nanotechnology in the health care setting has many potential benefits; however, our understanding of the interactions between nanoparticles and our immune system remains incomplete. Although many of the biological effects of nanoparticles are negatively correlated with particle size, some are clearly size specific and the mechanisms underlying these size-specific biological effects remain unknown. Here, we examined the pro-inflammatory effects of silica particles in THP-1 cells with respect to particle size; a large overall size range with narrow intervals between particle diameters (particle diameter: 10, 30, 50, 70, 100, 300, and 1,000 nm) was used...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28419916/a-sensitive-label-free-immunosensor-for-detection-%C3%AE-fetoprotein-in-whole-blood-based-on-anticoagulating-magnetic-nanoparticles
#14
Tingting Xu, Bo Chi, Fan Wu, Shangshang Ma, Shuyue Zhan, Meihui Yi, Hong Xu, Chun Mao
Accurate values of tumor markers in blood play an especially important role in the diagnosis of illness. Here, based on the combination of three techniques include anticoagulant technology, nanotechnology and biosensing technology, a sensitive label-free immunosensor with anti-biofouling electrode for detection α-Fetoprotein (AFP) in whole blood was developed by anticoagulating magnetic nanoparticles. The obtained products of Fe3O4-ɛ-PL-Hep nanoparticles were characterized by fourier transform infrared (FT-IR) spectra, transmission electron microscopy (TEM), ζ-potential and vibrating sample magnetometry (VSM)...
April 13, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28419240/from-nano-to-micro-using-nanotechnology-to-combat-microorganisms-and-their-multidrug-resistance
#15
Michal Natan, Ehud Banin
The spread of antibiotic resistance and increasing prevalence of biofilm-associated infections is driving demand for new means to treat bacterial infection. Nanotechnology provides an innovative platform for addressing this challenge, with potential to manage even infections involving multidrug-resistant (MDR) bacteria. The current review summarizes recent progress over the last 2 years in the field of antibacterial nanodrugs, and describes their unique properties, mode of action and activity against MDR bacteria and biofilms...
April 13, 2017: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/28419162/symmetry-based-assembly-of-a-2-dimensional-protein-lattice
#16
Sandra Poulos, Sayeh Agah, Nikardi Jallah, Salem Faham
The design of proteins that self-assemble into higher order architectures is of great interest due to their potential application in nanotechnology. Specifically, the self-assembly of proteins into ordered lattices is of special interest to the field of structural biology. Here we designed a 2 dimensional (2D) protein lattice using a fusion of a tandem repeat of three TelSAM domains (TTT) to the Ferric uptake regulator (FUR) domain. We determined the structure of the designed (TTT-FUR) fusion protein to 2.3 Å by X-ray crystallographic methods...
2017: PloS One
https://www.readbyqxmd.com/read/28418673/aberration-corrected-electron-beam-lithography-at-the-one-nanometer-length-scale
#17
Vitor Riseti Manfrinato, Aaron Stein, Lihua Zhang, Chang-Yong Nam, Kevin G Yager, Eric A Stach, Charles T Black
Patterning materials efficiently at the smallest length scales is a longstanding challenge in nanotechnology. Electron-beam lithography (EBL) is the primary method for patterning arbitrary features, but EBL has not reliably provided sub-4 nanometer patterns. The few competing techniques that have achieved this resolution are orders of magnitude slower than EBL. In this work, we employed an aberration-corrected scanning transmission electron microscope for lithography to achieve unprecedented resolution. Here we show aberration-corrected EBL at the one nanometer length scale using poly(methyl methacrylate) (PMMA), and have produced both the smallest isolated feature in any conventional resist (1...
April 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28416486/a-squalene-based-nanomedicine-for-oral-treatment-of-colon-cancer
#18
Larissa Kotelevets, Eric Chastre, Joachim Caron, Julie Mougin, Gerard Bastian, Alain Pineau, Francine Walker, Therese Lehy, Didier Desmaele, Patrick Couvreur
Nanotechnology offers many possibilities to improve drug treatments, including with regard to drug pharmacology. The current study reports a simple approach to improve cisplatin efficacy in the treatment of colon cancer through the creation of orally administered squalenoylated nanoparticles loaded with cisplatin (SQ-CDDP NP). Cytotoxic effects of SQ-CDDP NP were assessed in human colonic cells and in mouse models of intestinal cancer. In cell culture, SQ-CDDP NP exhibited at least 10-fold greater cytotoxic potency compared to uncomplexed cisplatin, reflecting an enhancement in intracellular accumulation and DNA platination...
April 17, 2017: Cancer Research
https://www.readbyqxmd.com/read/28415554/phytosynthesis-of-silver-nanoparticles-using-aqueous-leaf-extracts-of-lippia-citriodora-antimicrobial-larvicidal-and-photocatalytic-evaluations
#19
Elias E Elemike, Damian C Onwudiwe, Anthony C Ekennia, Richard C Ehiri, Nnaemeka J Nnaji
Nanoscience and nanotechnology represent new and enabling platforms that promise to provide broad range of novel and improved technologies for environmental, biological and other scientific applications. This study reports the synthesis of silver nanoparticles mediated by aqueous leaf extract of Lippia citriodora at two different temperatures of 50°C and 90°C. The synthesis of colloidal silver nanoparticles (AgNPs) was monitored by the use of UV-visible spectroscopy at different temperatures and time intervals...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28414914/designing-uniquely-addressable-bio-orthogonal-synthetic-scaffolds-for-dna-and-rna-origami
#20
Jerzy W Kozyra, Alessandro Ceccarelli, Emanuela Torelli, Annunziata Lopiccolo, Jing-Ying Gu, Harold Fellermann, Ulrich Stimming, Natalio Krasnogor
Nanotechnology and synthetic biology are rapidly converging, with DNA origami being one of the leading bridging technologies. DNA origami was shown to work well in a wide array of biotic environments. However, the large majority of extant DNA origami scaffolds utilize bacteriophages or plasmid sequences thus severely limiting its future applicability as bio-orthogonal nanotechnology platform. In this paper we present the design of biologically inert (i.e. "bio-orthogonal") origami scaffolds. The synthetic scaffolds have the additional advantage of being uniquely addressable (unlike biologically derived ones) and hence are better optimised for high-yield folding...
April 17, 2017: ACS Synthetic Biology
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