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https://www.readbyqxmd.com/read/28331178/habitat-filtering-and-exclusion-of-weak-competitors-jointly-explain-fern-species-assemblage-along-a-light-and-water-gradient
#1
Hui Zhang, Shidan Zhu, Robert John, Ronghua Li, Hui Liu, Qing Ye
Fern species are an important component of the diversity of forest plant communities, but very little is known about how fern communities assemble in different environments. In this study, we use multiple trait-based tests to examine the relationships between several key eco-physiological traits which are direct indicators of shade and drought tolerance, and the abundance of fern species in pine forest (PF), pine and mixed broad leaf forest (PMBF) and matured broad leaf forest (MBF) in southern China. These forests are characterized by decreasing light but increasing water availability during succession, and the fern communities correspondingly differ in species composition...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28299034/the-effect-of-a-lifestyle-modification-education-on-adiposity-measures-in-overweight-and-obese-nonalcoholic-fatty-liver-disease-patients
#2
Arman Arab, Gholamreza Askari, Parastoo Golshiri, Awat Feizi, Ali Hekmatnia, Bijan Iraj, Mojgan Nourian
BACKGROUND: Obesity is increasingly associated with nonalcoholic fatty liver disease (NAFLD) and weight loss through a combination of dietary modifications and increased physical activity is a primary goal of therapy in this disease. Therefore, this study was conducted to evaluate the effects of a lifestyle modification education on adiposity measures, physical activity, and total calorie intake in overweight and obese NAFLD patients. METHODS: During 8 weeks, 82 obese patients were randomly assigned into either an intervention group (n = 41) receiving a lifestyle modification education or to a control group (n = 41) receiving usual care...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28293274/optimally-repeatable-kinetic-model-variant-for-myocardial-blood-flow-measurements-with-82-rb-pet
#3
Adrian F Ocneanu, Robert A deKemp, Jennifer M Renaud, Andy Adler, Rob S B Beanlands, Ran Klein
Purpose. Myocardial blood flow (MBF) quantification with (82)Rb positron emission tomography (PET) is gaining clinical adoption, but improvements in precision are desired. This study aims to identify analysis variants producing the most repeatable MBF measures. Methods. 12 volunteers underwent same-day test-retest rest and dipyridamole stress imaging with dynamic (82)Rb PET, from which MBF was quantified using 1-tissue-compartment kinetic model variants: (1) blood-pool versus uptake region sampled input function (Blood/Uptake-ROI), (2) dual spillover correction (SOC-On/Off), (3) right blood correction (RBC-On/Off), (4) arterial blood transit delay (Delay-On/Off), and (5) distribution volume (DV) constraint (Global/Regional-DV)...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28292884/vascular-conductance-and-muscle-blood-flow-during-exercise-are-altered-by-inspired-oxygen-fraction-and-arterial-perfusion-pressure
#4
Rodrigo Villar, Richard L Hughson
We tested the hypothesis during the combined challenges of altered inspired O2 fraction (FIO2) and posture changes at lower power output regardless of body position that the vascular conductance (VC) recruitment to the exercising muscle would not limit muscle perfusion and estimated O2 delivery (DO2est ). However, in head-down tilt at the higher power output exercise in hypoxia, the recruitment of VC would have a functional limitation which would restrict muscle blood flow (MBF) leading to a limitation in DO2est with consequent increases in metabolic stress...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28273102/age-related-differences-in-skeletal-muscle-microvascular-response-to-exercise-as-detected-by-contrast-enhanced-ultrasound-ceus
#5
Wulf Hildebrandt, Hans Schwarzbach, Anita Pardun, Lena Hannemann, Björn Bogs, Alexander M König, Andreas H Mahnken, Olaf Hildebrandt, Ulrich Koehler, Ralf Kinscherf
BACKGROUND: Aging involves reductions in exercise total limb blood flow and exercise capacity. We hypothesized that this may involve early age-related impairments of skeletal muscle microvascular responsiveness as previously reported for insulin but not for exercise stimuli in humans. METHODS: Using an isometric exercise model, we studied the effect of age on contrast-enhanced ultrasound (CEUS) parameters, i.e. microvascular blood volume (MBV), flow velocity (MFV) and blood flow (MBF) calculated from replenishment of Sonovue contrast-agent microbubbles after their destruction...
2017: PloS One
https://www.readbyqxmd.com/read/28270281/application-of-the-low-dose-one-stop-shop-cardiac-ct-protocol-with-third-generation-dual-source-ct
#6
Lu Lin, Yining Wang, Yan Yi, Jian Cao, Lingyan Kong, Hao Qian, Hongzhi Zhang, Wei Wu, Yun Wang, Zhengyu Jin
Objective To evaluate the feasibility of a low-dose one-stop-shop cardiac CT imaging protocol with third-generation dual-source CT (DSCT). Methods Totally 23 coronary artery disease (CAD) patients were prospectively enrolled between March to September in 2016. All patients underwent an ATP stress dynamic myocardial perfusion imaging (MPI) (data acquired prospectively ECG-triggered during end systole by table shuttle mode in 32 seconds) at 70 kV combined with prospectively ECG-triggered high-pitch coronary artery angiography (CCTA) on a third-generation DSCT system...
February 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28254864/arterial-co2-as-a-potent-coronary-vasodilator-a-preclinical-pet-mr-validation-study-with-implications-for-cardiac-stress-testing
#7
Hsin-Jung Yang, Damini Dey, Jane Sykes, Michael Klein, John Butler, Michael Kovacs, Olivia Sobczyk, Behzad Sharif, Xiaoming Bi, Avinash Kali, Ivan Cokic, Richard Tang, Roya Yumul, Antonio Conte, Sotirios Tsaftaris, Mourad Tighiouart, Debiao Li, Piotr J Slomka, Daniel Berman, Frank Prato, Joseph Fisher, Rohan Dharmakumar
Myocardial blood flow (MBF) is the critical determinant of cardiac function. However, its response to increases in partial pressure of arterial CO2 (PaCO2), particularly with respect to adenosine, is not well characterized due to challenges in blood gas control and limited availability of validated approaches to ascertain MBF in vivo. By prospectively and independently controlling PaCO2 and combining it with (13)N-ammonia Positron Emission Tomography (PET) measurements, we investigated whether a physiologically tolerable hypercapnic stimulus (~25-mmHg increase in PaCO2) can increase MBF to that observed with adenosine in three groups of canines: (i) without coronary stenosis; (ii) subjected to non-flow limiting coronary stenosis; and (iii) following pre-administration of caffeine...
March 2, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28252111/bioresources-inner-recycling-between-bioflocculation-of-microcystis-aeruginosa-and-its-reutilization-as-a-substrate-for-bioflocculant-production
#8
Liang Xu, Mingxin Huo, Caiyun Sun, Xiaochun Cui, Dandan Zhou, John C Crittenden, Wu Yang
Bioflocculation, being environmental-friendly and highly efficient, is considered to be a promising method to harvest microalgae. However, one limitation of this technology is high expense on substrates for bioflocculant bacteria cultivation. In this regard, we developed an innovative method for the inner-recycling of biomass that could harvest the typical microalgae, Microcystis aeruginosa, using a bioflocculant produced by Citrobacter sp. AzoR-1. In turn, the flocculated algal biomass could be reutilized as a substrate for Citrobacter sp...
March 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28244122/influence-of-sustained-submaximal-clenching-fatigue-test-on-electromyographic-activity-and-maximum-voluntary-bite-forces-in-healthy-subjects-and-patients-with-temporomandibular-disorders
#9
L Xu, S Fan, B Cai, Z Fang, X Jiang
This study aimed to investigate whether the fatigue induced by sustained motor task in the jaw elevator muscles differed between healthy subjects and patients with temporomandibular disorder (TMD). Fifteen patients with TMD and thirteen age- and sex-matched healthy controls performed a fatigue test consisting of sustained clenching contractions at 30% maximal voluntary clenching(MVC) intensity until test failure(the criterion for terminating the fatigue test was when the biting force decreased by 10% or more from the target force consecutively for >3 seconds)...
February 28, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28242588/effects-of-successful-percutaneous-coronary-intervention-of-chronic-total-occlusions-on-myocardial-perfusion-and-left-ventricular-function
#10
Wijnand J Stuijfzand, P Stefan Biesbroek, Pieter G Raijmakers, Roel S Driessen, Stefan P Schumacher, Pepijn van Diemen, Jeffrey van den Berg, Robin Nijveldt, Adriaan A Lammertsma, Simon J Walsh, Colm G Hanratty, James C Spratt, Albert C van Rossum, Alexander Nap, Niels van Royen, Paul Knaapen
AIMS: The aim of the present study was to investigate the effects of successful PCI CTO on absolute myocardial blood flow (MBF) and functional recovery. METHODS AND RESULTS: Patients with a documented CTO were prospectively examined for ischemia and viability with H215O positron emission tomography (PET) and late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR). Sixty-nine consecutive patients, in whom PCI was successful, underwent follow-up PET and CMR after approximately 12 weeks to evaluate potential improvement of MBF as well as systolic function...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28228404/endothelial-colony-forming-cells-ameliorate-endothelial-dysfunction-via-secreted-factors-following-ischemia-reperfusion-injury
#11
Jason A Collett, Purvi Mehrotra, Allison Crone, W Christopher Shelley, Mervin C Yoder, David P Basile
Damage to endothelial cells contributes to acute kidney injury (AKI) by leading to impaired perfusion. Endothelial colony-forming cells (ECFCs) are endothelial precursor cells with high proliferative capacity, pro-angiogenic activity, and in vivo vessel forming potential. We hypothesized that ECFCs may ameliorate the degree of AKI and/or promote repair of the renal vasculature following ischemia/reperfusion (I/R). Rat pulmonary microvascular ECs (PMVEC) with high proliferative potential were compared with pulmonary artery ECs (PAEC) with low proliferative potential in rats subjected to renal I/R...
February 22, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28205113/cardiac-pet-ct-with-rb-82-optimization-of-image-acquisition-and-reconstruction-parameters
#12
P Chilra, S Gnesin, G Allenbach, M Monteiro, J O Prior, L Vieira, J A Pires Jorge
BACKGROUND: Our aim was to characterize the influence of time-of-flight (TOF) and point spread function (PSF) recovery corrections, as well as ordered subset expectation maximization (OSEM) reconstruction parameters, in (82)Rb PET/CT quantification of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Rest and stress list-mode dynamic (82)Rb PET acquisition data from 10 patients without myocardial flow defects and 10 patients with myocardial blood flow defects were reconstructed retrospectively...
December 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/28202246/analysis-of-myocardial-perfusion-parameters-in-an-ex-vivo-porcine-heart-model-using-third-generation-dual-source-ct
#13
Gert Jan Pelgrim, Taylor M Duguay, J Marco A Stijnen, Akos Varga-Szemes, Sjoerd Van Tuijl, U Joseph Schoepf, Matthijs Oudkerk, Rozemarijn Vliegenthart
PURPOSE: To evaluate the relationship between fractional flow reserve (FFR)-determined coronary artery stenosis severity and myocardial perfusion parameters derived from dynamic myocardial CT perfusion imaging (CTP) in an ex-vivo porcine heart model. METHODS: Six porcine hearts were perfused according to Langendorff. Circulatory parameters such as arterial blood flow (ABF) (L/min), mean arterial pressure (MAP) (mmHg) and heart rate (bpm) were monitored. Using an inflatable cuff and monitored via a pressure wire, coronary artery stenoses of different FFR grades were created (no stenosis, FFR = 0...
February 3, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28176182/rb-82-pet-ct-left-ventricular-mass-to-volume-ratios
#14
Andrew Van Tosh, Nathaniel Reichek, C David Cooke, Christopher J Palestro, Kenneth J Nichols
Left ventricular (LV) mass:volume ratios indexed to body size (Mi/Vi) provide risk stratification for cardiac events. We sought to determine whether Rb-82 PET mass and volume indices are similar to MRI normal values for low likelihood subjects, and whether abnormal indices are related to abnormal myocardial blood flow (MBF). Data were analyzed retrospectively for 194 patients referred for rest/stress Rb-82 PET. LV EF, volume and mass values were calculated and mass:volume ratios were indexed to patients' height and weight...
February 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28168868/oesophageal-doppler-guided-optimization-of-cardiac-output-does-not-increase-visceral-microvascular-blood-flow-in-healthy-volunteers
#15
Thomas P Heinink, David J Read, William K Mitchell, Ashish Bhalla, Jonathan N Lund, Bethan E Phillips, John P Williams
BACKGROUND: Oesophageal Doppler monitoring (ODM) is used clinically to optimize cardiac output (CO) and guide fluid therapy. Despite limited experimental evidence, it is assumed that increasing CO increases visceral microvascular blood flow (MBF). We used contrast-enhanced ultrasound (CEUS) to assess whether ODM-guided optimization of CO altered MBF. METHODS: Sixteen healthy male volunteers (62 ± 3·4 years) were studied. Baseline measurements of CO were recorded via ODM...
February 6, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28160262/comparison-between-the-summed-difference-score-and-myocardial-blood-flow-measured-by-13-n-ammonia
#16
Raffaele Giubbini, Alessia Peli, Elisa Milan, Roberto Sciagrà, Luca Camoni, Domenico Albano, Mattia Bertoli, Mattia Bonacina, Federica Motta, Massimo Statuto, Carlo Alberto Rodella, Antonio De Agostini, Raffaella Calabretta, Francesco Bertagna
BACKGROUND: Both the myocardial perfusion pattern and myocardial blood flow (MBF) are used to assess patients with suspected coronary artery disease (CAD). The aim of this study was to compare the perfusion pattern (using the summed difference score [SDS]) to MBF in a consecutive group of patients undergoing PET/CT with 13 N-ammonia ((13)NH3). METHODS: 47 consecutive patients, aged 65 ± 12 years (42 men) with known or suspected CAD, underwent vasodilator stress/rest PET/CT with (13)NH3 for clinical indications...
February 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28152238/assessment-of-segmental-myocardial-blood-flow-and-myocardial-perfusion-reserve-by-adenosine-stress-myocardial-arterial-spin-labeling-perfusion-imaging
#17
Andrew J Yoon, Hung Phi Do, Steven Cen, Michael W Fong, Farhood Saremi, Mark L Barr, Krishna S Nayak
PURPOSE: To determine the feasibility of measuring increases in myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) on a per-segment basis using arterial spin labeled (ASL) magnetic resonance imaging (MRI) with adenosine vasodilator stress in normal human myocardium. MATERIALS AND METHODS: Myocardial ASL scans at rest and during adenosine infusion were incorporated into a routine 3T MR adenosine-induced vasodilator stress protocol and were performed in 10 healthy human volunteers...
February 2, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28138813/noninvasive-pet-quantitative-myocardial-blood-flow-with-regadenoson-for-assessing-cardiac-allograft-vasculopathy-in-orthotopic-heart-transplantation-patients
#18
Miguel Hernandez Pampaloni, Uttam M Shrestha, Maria Sciammarella, Youngho Seo, Grant T Gullberg, Elias H Botvinick
BACKGROUND: Risk stratification and early detection of cardiac allograft vasculopathy (CAV) is essential in orthotopic heart transplantation (OHT) patients. This study assesses the changes in myocardial blood flow (MBF) noninvasively in OHT patients using quantitative cardiac PET with regadenoson. METHODS: Twelve patients (Group 1) (8 males, 4 females, mean age 55 ± 7 years) with no history of post OHT myocardial ischemia were enrolled 5.4 ± 2.0 years after OHT...
January 30, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28137454/residual-activity-correction-in-quantitative-myocardial-perfusion-13-n-ammonia-pet-imaging-a-study-in-post-mi-patients
#19
George Markousis-Mavrogenis, Luis Eduardo Juárez-Orozco, Erick Alexanderson
BACKGROUND/INTRODUCTION/AIM: Positron Emission Tomography (PET) is the gold standard for quantification of Myocardial Blood Flow (MBF). A standard PET scan is acquired in two phases (rest and pharmacological stress). (13)N-ammonia is a perfusion radiotracer that may show residual activity which may affect MBF estimation during the second phase of the scan. An algorithm for Residual Activity Correction (RAC) is available when reconstruction is performed using Syngo MBF (by Siemens). The aim of this study was to evaluate differentes in MBF estimation with and without RAC by Syngo MBF in patients with a previous MI using (13)N-ammonia PET...
January 27, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28130886/classification-of-hemodynamically-significant-stenoses-from-dynamic-ct-perfusion-and-cta-myocardial-territories
#20
Marco Giordano, Dirk H J Poot, Adriaan Coenen, Theo van Walsum, Michela Tezza, Koen Nieman, Wiro J Niessen
PURPOSE: Myocardial blood flow (MBF) obtained by dynamic CT perfusion (CTP) has been recently introduced to assess hemodynamic significance of coronary stenosis in coronary artery disease. The diagnostic performance of dynamic CTP MBF is limited due to subjective interpretation of MBF maps and MBF variations caused by physiological, methodological and technical issues. In this paper we introduce a novel method to quantify the hypoperfused volume (HPV) in myocardial territories derived from CT angiography (CTA) in order to overcome the limitations of current dynamic CTP MBF analysis methods...
January 28, 2017: Medical Physics
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