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endothelial keratoplasty

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https://www.readbyqxmd.com/read/29679087/optical-and-tectonic-corneal-transplant-outcomes-in-a-tertiary-hospital-in-singapore-within-the-singapore-corneal-transplant-registry
#1
Dawn Ho, Charmaine Chai, Hazel Lin, Hla Myint Htoon, Anna Marie Tan, Ray Manotosh, Donald Tan
INTRODUCTION: This study aimed to describe and compare corneal graft survival and optical outcomes following deep anterior lamellar keratoplasty (DALK) and Descemet's stripping automated endothelial keratoplasty (DSAEK) with penetrating keratoplasty (PK), and to document tectonic success of patch grafts. MATERIALS AND METHODS: This was a retrospective, non-randomised, comparative and descriptive cohort study. A total of 139 eyes that underwent primary keratoplasty between 2000 and 2016 were included, and the following data was extracted: demographics, clinical diagnosis and primary indication, pre- and intraoperative risk factors, postkeratoplasty outcomes, and complications...
March 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29676320/unveiling-opacification-of-intraocular-lens-following-a-successful-penetrating-keratoplasty-for-extensively-scarred-cornea-due-to-microbial-keratitis-after-descemet-s-stripping-automated-endothelial-keratoplasty
#2
https://www.readbyqxmd.com/read/29675378/complications-and-outcomes-of-descemet-stripping-automated-endothelial-keratoplasty-with-artisan-aphakia-intraocular-lens-implantation
#3
Rong-Mei Peng, Yu-Xin Guo, Yuan Qiu, Yan-Sheng Hao, Jing Hong
AIM: To evaluate the complications and outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) combined with artisan aphakia intraocular lens (IOL) implantation in severely damaged eyes without capsular support. METHODS: DSAEK combined with artisan iris claw IOL implantation was performed on 29 eyes. All eyes were of abnormal structure due to complications from prior intraocular surgeries and ocular trauma. Ocular complications observed included graft dislocations, high intraocular pressure (IOP), IOL dislocations, macular edema and hyphema...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675350/postoperative-intraocular-lens-opacification
#4
Shang-Te Ma, Chung-May Yang, Yu-Chih Hou
Intraocular lens (IOL) opacification is rare but may occur after non-Descemet stripping automated endothelial keratoplasty (n-DSAEK) or intravitreal air injection after pars plana vitrectomy (PPV). We reported two cases of IOL opacification within the pupillary region. Chart was retrospectively reviewed. The predisposing factors and the visual acuity were analyzed. The opacification was evaluated by anterior segment optical coherence tomography (AS-OCT). A 68-year-old healthy woman with pseudophakic bullous keratopathy underwent uneventful n-DSAEK in the right eye...
January 2018: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29673628/-descemet-s-membrane-endothelial-keratoplasty-indication-surgical-technic-postoperative-management-and-review-of-literature
#5
REVIEW
V Kocaba, O Damour, C Auxenfans, C Burillon
Endothelial keratoplasty is currently the preferred method for the treatment of endothelial dysfunctions and dystrophies. Descemet Membrane Endothelial Keratoplasty (DMEK), described by Gerrit Melles in 2006, is performed by selectively replacing the damaged endothelium with a healthy counterpart. It leads to a faster visual recovery and better refractive outcomes with a limited risk of rejection compared to Descemet's Stripping Automated Endothelial Keratosplasty (DSAEK), which includes a thin stromal layer...
April 17, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29672430/recovery-of-corneal-clarity-after-dmek-followed-by-rebubbling-versus-uneventful-dmek
#6
Apostolos Lazaridis, Ourania Fydanaki, Eleftherios Giallouros, Ilias Georgalas, George Kymionis, Walter Sekundo, Konstantinos Droutsas
PURPOSE: To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS: Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DMEK cases followed by 1 rebubbling; group 2a (n = 55), including uneventful DMEK cases with complete graft attachment; and group 2b (n = 25), including uneventful DMEK cases with minor peripheral detachment, not requiring rebubbling...
April 19, 2018: Cornea
https://www.readbyqxmd.com/read/29670326/iridocorneal-endothelial-syndrome-clinical-perspectives
#7
REVIEW
Andrew Walkden, Leon Au
This article aims to review the clinical management strategies available for the rare iridocorneal endothelial syndrome. The different clinical variations as well as the imaging techniques available to aid diagnosis are discussed. We then present the evidence available to help the reader to understand how the condition can be managed medically and also the important surgical aspects of treatment. This involves raised intraocular pressure management in addition to the visual management options of partial or full thickness keratoplasty...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29668572/atypical-presentation-of-iridocorneal-endothelial-syndrome-with-band-keratopathy-but-no-corneal-edema-managed-with-descemet-membrane-endothelial-keratoplasty
#8
Vasiliki Zygoura, Itay Lavy, Robert M Verdijk, Diana Santander-García, Lamis Baydoun, Isabel Dapena, Gerrit R J Melles
PURPOSE: To report an unusual presentation of iridocorneal endothelial (ICE) syndrome associated with band keratopathy and its management with ethylenediamine-tetraacetic acid (EDTA) chelation and Descemet membrane endothelial keratoplasty (DMEK). METHODS: A 57-year-old female patient presented with unilateral progressive painless visual impairment, corneal band keratopathy, and morphological corneal endothelial changes without corneal edema or any previous ophthalmic, medical, or family history...
April 17, 2018: Cornea
https://www.readbyqxmd.com/read/29664749/meta-analysis-of-descemet-membrane-endothelial-keratoplasty-versus-descemet-stripping-automated-endothelial-keratoplasty-postoperative-visual-outcomes
#9
https://www.readbyqxmd.com/read/29661044/dmek-versus-dsaek-for-fuchs-endothelial-dystrophy-a-meta-analysis
#10
Raquel Esteves Marques, Paulo Silva Guerra, David Cordeiro Sousa, Ana Inês Gonçalves, Ana Miguel Quintas, Walter Rodrigues
PURPOSE: To compare the safety and efficacy profiles of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in adult patients with Fuchs' endothelial dystrophy. METHODS: Electronic database search on MEDLINE and CENTRAL from inception to August 2017. We included all comparative studies of DMEK versus DSAEK in patients with diagnosed Fuchs' endothelial dystrophy. Studies assessing rescue procedures were excluded to minimize bias...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29649920/corneal-transplantation-trends-in-france-from-2004-to-2015-a-12-year-review
#11
Guillaume Bigan, Marc Puyraveau, Maher Saleh, Philippe Gain, Isabelle Martinache, Bernard Delbosc, Anne-Sophie Gauthier
PURPOSE: The aim of this study was to report the 12-year longitudinal trends in indication and corneal transplantation techniques in France from 2004 to 2015. RESULTS: The records of all corneal transplantations performed from 2004 to 2015 in France were retrospectively reviewed. The patient indications and types of transplant performed were analyzed. A total of 46,658 corneal transplantations were performed between 2004 and 2015, with 34,187 (73.3%) penetrating keratoplasty and 10,452 (22...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29643797/uneventful-anterior-migration-of-intravitreal-ozurdex-implant-in-a-patient-with-iris-sutured-intraocular-lens-and-descemet-stripping-automated-endothelial-keratoplasty
#12
Andleeb Zafar, Ioannis M Aslanides, Vasileios Selimis, Konstantinos I Tsoulnaras, David Tabibian, George D Kymionis
Purpose: We report here the case of a patient with anterior segment migration of intravitreal dexamethasone implant as well as its management and outcome. Methods: The patient had the following sequence of events: complicated cataract surgery, iris-sutured intraocular lens implant, followed by cystoid macular edema treated with intravitreal Avastin, retinal vein occlusion treated with intravitreal dexamethasone implant, corneal decompensation treated with Descemet stripping automated endothelial keratoplasty (DSAEK), and finally recurrence of macular edema treated with repeated intravitreal dexamethasone implant...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29624509/graft-detachment-pattern-after-descemet-membrane-endothelial-keratoplasty-comparing-air-versus-20-sf6-tamponade
#13
Sebastian Siebelmann, Sebastian Lopez Ramos, Paula Scholz, Mario Matthaei, Silvia Schrittenlocher, Ludwig M Heindl, Björn Bachmann, Claus Cursiefen
PURPOSE: The change from air to 20% sulfur hexafluoride (SF6) as anterior chamber tamponade for Descemet membrane endothelial keratoplasty (DMEK) significantly reduced the rebubbling rate. Nonetheless, underlying mechanisms are not completely understood. In this study, we investigate the morphology of graft detachments after DMEK depending on the tamponade and its influence on postoperative rebubbling. METHODS: In this retrospective analysis of prospective data of 204 consecutive patients who underwent DMEK with 100% air, or 20% SF6, we compared the SF6 group with the air group regarding the number, lateral and axial diameter and localization of detachments, visual acuity (BSCVA), and incidence of rebubbling after 1 week (T1), after 1 (T2), 3 (T3), 6 (T4), and 12 (T5) months postoperatively...
April 5, 2018: Cornea
https://www.readbyqxmd.com/read/29624508/viscoleastic-tamponade-applied-to-the-ocular-surface-for-enhanced-control-of-gaseous-egress-from-the-anterior-chamber-during-final-bubble-titration-in-dmek-surgery-the-polite-burp
#14
Christopher S Sales, Ana Alzaga Fernandez, Zane Anwar
PURPOSE: To present a novel technique for enhancing the surgeon's control over the volume of air or gas that is "burped" from the anterior chamber during final bubble and intraocular pressure (IOP) titration in Descemet membrane endothelial keratoplasty. METHODS: After ascertaining that the intracameral bubble is either too large and/or has rendered IOP too high, a bead of ophthalmic viscoelastic is applied to the ocular surface over a paracentesis incision, which is then depressed in the usual fashion to burp gas from the anterior chamber...
April 5, 2018: Cornea
https://www.readbyqxmd.com/read/29619650/endothelial-keratoplasty-in-eyes-with-a-retained-angle-supported-intraocular-lens
#15
Konstantinos Droutsas, Apostolos Lazaridis, George Kymionis, Klio Chatzistefanou, Dimitris Papaconstantinou, Walter Sekundo, Chryssanthi Koutsandrea
PURPOSE: To describe the outcomes of endothelial keratoplasty (EK) for bullous keratopathy in eyes with a retained angle-supported anterior chamber intraocular lens (acIOL). METHODS: Among 263 consecutive EK procedures, 7 DMEK and 11 DSAEK procedures were identified in eyes with an acIOL and included in the present retrospective case series. Pre- and postoperative status including ocular history, anatomical outcome and complications as well as best-corrected visual acuity was evaluated...
April 4, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29607781/effect-of-donor-cornea-on-the-surgical-outcomes-of-penetrating-keratoplasty-imported-cornea-versus-domestic-cornea
#16
Evin Singar-Ozdemir, Ayse Burcu, Baris Oral, Zuleyha Yalniz-Akkaya, Selma Uzman, Sema Tamer Kaderli, Firdevs Ornek
OBJECTIVES: In this study, we compared the surgical outcomes of penetrating keratoplasty using domestic and imported donor corneas. MATERIALS AND METHODS: We retrospectively evaluated 200 eyes and 200 consecutive patients who underwent penetrating keratoplasty by using domestic and imported donor corneas between January 2013 and December 2013. The donor characteristics, preoperative clinical features, and clinical outcomes at 6, 12, 24, and 36 months were assessed...
April 2, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29595764/use-of-donor-corneas-from-pseudophakic-eyes-for-descemet-membrane-endothelial-keratoplasty
#17
Thabo Lapp, Sonja Heinzelmann, Daniel Böhringer, Philipp Eberwein, Thomas Reinhard, Philip Maier
PURPOSE: The prevalence of pseudophakia increases with age and affects more than 30% of people older than 80 years. Because grafts from older donors seem to be more suitable for Descemet membrane endothelial keratoplasty (DMEK) surgery rather than grafts from younger donors, eye bank technicians and corneal surgeons have to deal with corneas from pseudophakic donors for DMEK graft preparation. However, graft preparation from corneas of pseudophakic donors can be more complicated. METHODS: We retrospectively analyzed our donor registry for the prevalence of pseudophakia...
March 27, 2018: Cornea
https://www.readbyqxmd.com/read/29595762/transplantation-blues-inadvertent-staining-of-amyloid-deposits-with-trypan-blue
#18
Agathe Marcon, Nicolas Périllat, Thibaud Garcin, Rémy Jullienne, Zhiguo He, Fabien Forest, Anne Sophie Gauthier, Philippe Gain, Gilles Thuret
PURPOSE: To describe inadvertent persistent staining of stromal amyloid deposits by trypan blue (TB) after penetrating keratoplasty (PK) and Descemet membrane endothelial keratoplasty (DMEK) performed in patients with corneal amyloidosis. METHODS: Case series of patients with corneal amyloidosis in whom intraoperative TB was used. RESULTS: One patient, hospitalized for acute rejection 6 weeks after DMEK, presented with an intense blue staining of small, spindle-shaped structures in the anterior half of the cornea...
March 27, 2018: Cornea
https://www.readbyqxmd.com/read/29573998/painless-bilateral-bullous-keratopathy
#19
Stephen J Vincent
Bullous keratopathy is a pathological corneal condition that arises due to irreversible oedema associated with endothelial cell loss or dysfunction. Symptoms may vary from mild (transient blurred vision and increased glare from epithelial oedema) to severe (an acute and significant loss of vision associated with frank endothelial decompensation, and pain due to ruptured epithelial bullae). Possible treatments to restore vision and minimise pain include topical hypertonic agents, bandage contact lenses, superficial anterior corneal surgical procedures or penetrating full thickness or endothelial keratoplasty...
March 21, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29561351/cumulative-endothelial-cell-loss-in-descemet-membrane-endothelial-keratoplasty-grafts-from-preparation-through-insertion-with-glass-injectors
#20
Kenneth Downes, Khoa D Tran, Christopher G Stoeger, Winston Chamberlain
PURPOSE: Evaluation of cumulative Descemet membrane endothelial keratoplasty endothelial cell loss (ECL) from preparation through injection using 2 different glass injectors. METHODS: Eighteen Descemet membrane endothelial keratoplasty grafts with "S" stamps were prepared by eye bank technicians. Nine grafts were assigned to injection with a modified glass Jones tube injector with a 2.4-mm opening and 9 were assigned to injection with the DORC glass pipette injector (<1...
March 20, 2018: Cornea
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