keyword
MENU ▼
Read by QxMD icon Read
search

Dodick d

keyword
https://www.readbyqxmd.com/read/29504483/a-multicenter-prospective-single-arm-open-label-observational-study-of-stms-for-migraine-prevention-espouse-study
#1
Amaal J Starling, Stewart J Tepper, Michael J Marmura, Ejaz A Shamim, Matthew S Robbins, Nada Hindiyeh, Andrew C Charles, Peter J Goadsby, Richard B Lipton, Stephen D Silberstein, Amy A Gelfand, Richard P Chiacchierini, David W Dodick
Objective To evaluate the efficacy and tolerability of single pulse transcranial magnetic stimulation (sTMS) for the preventive treatment of migraine. Background sTMS was originally developed for the acute treatment of migraine with aura. Open label experience has suggested a preventive benefit. The objective of this trial was to evaluate the efficacy and tolerability of sTMS for migraine prevention. Methods The eNeura SpringTMS Post-Market Observational U.S. Study of Migraine (ESPOUSE) Study was a multicenter, prospective, open label, observational study...
May 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29504482/guidelines-of-the-international-headache-society-for-controlled-trials-of-preventive-treatment-of-chronic-migraine-in-adults
#2
Cristina Tassorelli, Hans-Christoph Diener, David W Dodick, Stephen D Silberstein, Richard B Lipton, Messoud Ashina, Werner J Becker, Michel D Ferrari, Peter J Goadsby, Patricia Pozo-Rosich, Shuu-Jiun Wang
Background Quality clinical trials form an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for Controlled Trials of Drugs in Migraine. In 2008, the Committee published the first specific guidelines on chronic migraine. Subsequent advances in drug, device, and biologicals development, as well as novel trial designs, have created a need for a revision of the chronic migraine guidelines...
April 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29471679/arise-a-phase-3-randomized-trial-of-erenumab-for-episodic-migraine
#3
David W Dodick, Messoud Ashina, Jan Lewis Brandes, David Kudrow, Michel Lanteri-Minet, Vera Osipova, Kerry Palmer, Hernan Picard, Daniel D Mikol, Robert A Lenz
Background Calcitonin gene-related peptide plays an important role in migraine pathophysiology. Erenumab, a human monoclonal antibody that inhibits the calcitonin gene-related peptide receptor, is being evaluated for migraine prevention. Methods In this randomized, double-blind, placebo-controlled, phase 3 study, 577 adults with episodic migraine were randomized to placebo or 70 mg erenumab; 570 patients were included in efficacy analyses. Primary endpoint was change in monthly migraine days. Secondary endpoints were ≥50% reduction in monthly migraine days, change in acute migraine-specific medication treatment days, and ≥5-point reduction in Physical Impairment and Impact on Everyday Activities domain scores measured by the Migraine Physical Function Impact Diary...
May 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29431168/king-devick-test-identifies-real-time-concussion-and-asymptomatic-concussion-in-youth-athletes
#4
Priya S Dhawan, Danielle Leong, Lisa Tapsell, Amaal J Starling, Steven L Galetta, Laura J Balcer, Trenton L Overall, Jennifer S Adler, Rashmi B Halker-Singh, Bert B Vargas, David Dodick
Background: Sports concussion has an annual incidence of approximately 3.8 million. Over half go unreported and a substantial number may be asymptomatic. A rapid, cost-effective, and reliable tool that facilitates diagnosis of concussion is needed. The King-Devick (K-D) test is a vision-based tool of rapid number naming for assessment of concussion. In this study, we evaluated the utility of the K-D test in real time for identification of symptomatic concussion in youth athletes and to determine if similar impairment (subclinical concussion) exists in youth athletes without an obvious head injury or symptoms...
December 2017: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/29297655/the-emerging-role-of-gammacore-in-the-management-of-cluster-headache-expert-panel-recommendations
#5
Stephen D Silberstein, Anne H Calhoun, Christina Treppendahl, David W Dodick, Alan M Rapoport, Avinash Mamidi, Peter Vargas, Thomas H Ebert, Stewart J Tepper
A panel of 9 experts, including neurologists, other headache specialists, and medical and pharmacy directors, from 4 health plans (1 integrated delivery network and 3 plans with commercial, Medicare, and Medicaid lines of business), convened to discuss cluster headache (CH). Topics covered included the current treatment landscape, treatment challenges, economic impact of disease, and gaps in care for patients with CH. One major challenge in the management of CH is that it is underrecognized and frequently misdiagnosed, leading to delays in and suboptimal treatment for patients who suffer from this painful and disabling condition...
November 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29171818/fremanezumab-for-the-preventive-treatment-of-chronic-migraine
#6
RANDOMIZED CONTROLLED TRIAL
Stephen D Silberstein, David W Dodick, Marcelo E Bigal, Paul P Yeung, Peter J Goadsby, Tricia Blankenbiller, Melissa Grozinski-Wolff, Ronghua Yang, Yuju Ma, Ernesto Aycardi
BACKGROUND: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a preventive treatment for migraine. We compared two fremanezumab dose regimens with placebo for the prevention of chronic migraine. METHODS: In this phase 3 trial, we randomly assigned patients with chronic migraine (defined as headache of any duration or severity on ≥15 days per month and migraine on ≥8 days per month) in a 1:1:1 ratio to receive fremanezumab quarterly (a single dose of 675 mg at baseline and placebo at weeks 4 and 8), fremanezumab monthly (675 mg at baseline and 225 mg at weeks 4 and 8), or matching placebo...
November 30, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29144718/the-emerging-role-of-gammacore%C3%A2-in-the-management-of-cluster-headache-expert-panel-recommendations
#7
Stephen D Silberstein, Anne H Calhoun, Christina Treppendahl, David W Dodick, Alan M Rapoport, Avinash Mamidi, Peter Vargas, Thomas H Ebert, Stewart J Tepper
A panel of 9 experts, including neurologists, other headache specialists, and medical and pharmacy directors, from 4 health plans (1 integrated delivery network and 3 plans with commercial, Medicare, and Medicaid lines of business), convened to discuss cluster headache (CH). Topics covered included the current treatment landscape, treatment challenges, economic impact of disease, and gaps in care for patients with CH. One major challenge in the management of CH is that it is underrecognized and frequently misdiagnosed, leading to delays in and suboptimal treatment for patients who suffer from this painful and disabling condition...
November 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28835404/erenumab-amg-334-in-episodic-migraine-interim-analysis-of-an-ongoing-open-label-study
#8
Messoud Ashina, David Dodick, Peter J Goadsby, Uwe Reuter, Stephen Silberstein, Feng Zhang, Julia R Gage, Sunfa Cheng, Daniel D Mikol, Robert A Lenz
OBJECTIVE: To assess long-term safety and efficacy of anti-calcitonin gene-related peptide receptor erenumab in patients with episodic migraine (EM). METHODS: Patients enrolled in a 12-week, double-blind, placebo-controlled clinical trial (NCT01952574) who continued in an open-label extension (OLE) study will receive erenumab 70 mg every 4 weeks for up to 5 years. This preplanned interim analysis, conducted after all participants had completed the 1-year open-label follow-up, evaluated changes in monthly migraine days (MMD), achievement of ≥50%, ≥75%, and 100% reductions, Headache Impact Test (HIT-6) score, Migraine-Specific Quality of Life (MSQ), Migraine Disability Assessment (MIDAS), and safety...
September 19, 2017: Neurology
https://www.readbyqxmd.com/read/28387038/insights-into-the-functional-anatomy-behind-the-preempt-injection-paradigm-guidance-on-achieving-optimal-outcomes
#9
Andrew M Blumenfeld, Stephen D Silberstein, David W Dodick, Sheena K Aurora, Mitchell F Brin, William J Binder
OBJECTIVE: To provide clinically relevant insights on the identification of the muscles and techniques involved in the safe and effective use of onabotulinumtoxinA for chronic migraine prophylaxis. BACKGROUND: Although guidance on the use of onabotulinumtoxinA for chronic migraine is available, based on the Phase III Research Evaluating Migraine Prophylaxis Therapy (PREEMPT) clinical program, clinical experience has shown that insufficient understanding of the anatomy and function of the head and neck muscles may lead to undesirable outcomes and suboptimal efficacy...
May 2017: Headache
https://www.readbyqxmd.com/read/27970615/development-of-a-responder-definition-for-the-migraine-physical-function-impact-diary-mpfid
#10
A K Kawata, R Hsieh, S Sapra, P R Desai, B G Ortmeier, J L Poon, S Tepper, W Stewart, D W Dodick, A Hareendran
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27531288/untoward-events-associated-with-aberrant-fluid-infusion-during-cataract-surgery-laboratory-study-with-corroborative-clinical%C3%A2-observations
#11
Richard S Koplin, David C Ritterband, Jack M Dodick, Eric D Donnenfeld, Mark Schafer
PURPOSE: To determine the relationship between untoward events noted during phacoemulsification surgery associated with aberrant infusion misdirection and their causal relationship to current infusion sleeve design. SETTING: The New York Eye & Ear Infirmary of Mt. Sinai, New York, New York, USA. DESIGN: Retrospective case reports and experimental study. METHODS: Observations of live cataract surgery were documented with high-definition videography using 3 commercial phacoemulsification platforms...
August 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27181270/migraine-what-imaging-reveals
#12
REVIEW
Catherine D Chong, Todd J Schwedt, David W Dodick
Although migraine symptomatology is well-defined, our understanding of migraine pathophysiology is incomplete. Structural and functional brain imaging can contribute to a greater understanding of migraine pathophysiology. Recent neuroimaging studies demonstrate that migraine is associated with structural and functional alterations of brain regions commonly implicated in pain processing. This review summarizes recent brain structural and functional imaging findings in migraine and highlights those that are associated with characteristics such as the presence or absence of aura, associated cognitive dysfunction, sex-differences (male vs...
July 2016: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/25934848/milestone-compatible-neurology-resident-assessments-a-role-for-observable-practice-activities
#13
Lyell K Jones, Elliot L Dimberg, Christopher J Boes, Scott D Z Eggers, David W Dodick, Jeremy K Cutsforth-Gregory, Andrea N Leep Hunderfund, David J Capobianco
OBJECTIVE: Beginning in 2014, US neurology residency programs were required to report each trainee's educational progression within 29 neurology Milestone competency domains. Trainee assessment systems will need to be adapted to inform these requirements. The primary aims of this study were to validate neurology resident assessment content using observable practice activities (OPAs) and to develop assessment formats easily translated to the Neurology Milestones. METHODS: A modified Delphi technique was used to establish consensus perceptions of importance of 73 neurology OPAs among neurology educators and trainees at 3 neurology residency programs...
June 2, 2015: Neurology
https://www.readbyqxmd.com/read/25505036/late-life-migraine-accompaniments-a-narrative-review
#14
REVIEW
Kiratikorn Vongvaivanich, Paweena Lertakyamanee, Stephen D Silberstein, David W Dodick
BACKGROUND: Migraine is one of the most common chronic neurological disorders. In 1980, C. Miller Fisher described late-life migraine accompaniments as transient neurological episodes in older individuals that mimic transient ischemic attacks. There has not been an update on the underlying nature and etiology of late-life migraine accompanimentsd since the original description. PURPOSE: The purpose of this article is to provide a comprehensive and extensive review of the late-life migraine accompaniments including the epidemiology, clinical characteristics, differential diagnosis, and treatment...
September 2015: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/25500317/per-cent-of-patients-with-chronic-migraine-who-responded-per-onabotulinumtoxina-treatment-cycle-preempt
#15
RANDOMIZED CONTROLLED TRIAL
Stephen D Silberstein, David W Dodick, Sheena K Aurora, Hans-Christoph Diener, Ronald E DeGryse, Richard B Lipton, Catherine C Turkel
OBJECTIVE: The approved use of onabotulinumtoxinA for prophylaxis of headaches in patients with chronic migraine (CM) involves treatment every 12 weeks. It is currently unknown whether patients who fail to respond to the first onabotulinumtoxinA treatment cycle will respond to subsequent treatment cycles. To help inform decisions about treating non-responders, we examined the probability of treatment cycle 1 non-responders responding in cycle 2, and cycle 1 and 2 non-responders responding in cycle 3...
September 2015: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/25496899/functional-mri-of-migraine
#16
REVIEW
Todd J Schwedt, Chia-Chun Chiang, Catherine D Chong, David W Dodick
Migraine is a disabling neurological condition manifesting with attacks of headache, hypersensitivities to visual, auditory, olfactory and somatosensory stimuli, nausea, and vomiting. Exposure to sensory stimuli, such as odours, visual stimuli, and sounds, commonly triggers migraine attacks, and hypersensitivities to sensory stimuli are prominent during migraine attacks, but can persist with less magnitude between attacks. Functional MRI (fMRI) has been used to investigate the mechanisms that lead to migraine sensory hypersensitivities by measuring brain responses to visual, olfactory, and painful cutaneous stimulation, and functional connectivity analyses have investigated the functional organisation of specific brain regions and networks responsible for sensory processing...
January 2015: Lancet Neurology
https://www.readbyqxmd.com/read/25464159/assessing-clinically-meaningful-treatment-effects-in-controlled-trials-chronic-migraine-as-an-example
#17
David W Dodick, Catherine C Turkel, Ronald E DeGryse, Hans-Christoph Diener, Richard B Lipton, Sheena K Aurora, Marissa E Nolan, Stephen D Silberstein
UNLABELLED: In addition to headache, persons with chronic migraine (CM) experience multiple symptoms, both ictal and interictal, that may contribute to their suffering. Translating clinical trial results into practice requires assessment of the results' clinical meaningfulness. When examining treatment benefit in this disabled patient population, multiple headache-symptom measures should be considered to fully reflect clinical relevance. Currently, only onabotulinumtoxinA is approved specifically for headache prophylaxis in adults with CM...
February 2015: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/25297013/safety-and-efficacy-of-ald403-an-antibody-to-calcitonin-gene-related-peptide-for-the-prevention-of-frequent-episodic-migraine-a-randomised-double-blind-placebo-controlled-exploratory-phase-2-trial
#18
RANDOMIZED CONTROLLED TRIAL
David W Dodick, Peter J Goadsby, Stephen D Silberstein, Richard B Lipton, Jes Olesen, Messoud Ashina, Kerri Wilks, David Kudrow, Robin Kroll, Bruce Kohrman, Robert Bargar, Joe Hirman, Jeff Smith
BACKGROUND: Calcitonin gene-related peptide (CGRP) is crucial in the pathophysiology of migraine. We assessed the safety, tolerability, and efficacy of ALD403, a genetically engineered humanised anti-CGRP antibody, for migraine prevention. METHODS: In this randomised, double-blind, placebo-controlled, exploratory, proof-of-concept phase 2 trial, patients aged 18-55 years with five to 14 migraine days per 28-day period were randomly assigned (1:1) via an interactive web response system to receive an intravenous dose of ALD403 1000 mg or placebo...
November 2014: Lancet Neurology
https://www.readbyqxmd.com/read/25078718/safety-and-efficacy-of-peripheral-nerve-stimulation-of-the-occipital-nerves-for-the-management-of-chronic-migraine-long-term-results-from-a-randomized-multicenter-double-blinded-controlled-study
#19
RANDOMIZED CONTROLLED TRIAL
David W Dodick, Stephen D Silberstein, Kenneth L Reed, Timothy R Deer, Konstantin V Slavin, Billy Huh, Ashwini D Sharan, Samer Narouze, Alon Y Mogilner, Terrence L Trentman, Joe Ordia, Julien Vaisman, Jerome Goldstein, Nagy Mekhail
BACKGROUND: Recent studies evaluated short-term efficacy and safety of peripheral nerve stimulation (PNS) of the occipital nerves for managing chronic migraine. We present 52-week safety and efficacy results from an open-label extension of a randomized, sham-controlled trial. METHODS: In this institutional review board-approved, randomized, multicenter, double-blinded study, patients were implanted with a neurostimulation system, randomized to an active or control group for 12 weeks, and received open-label treatment for an additional 40 weeks...
April 2015: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/24990187/operational-diagnostic-criteria-for-chronic-migraine-expert-opinion
#20
REVIEW
Stephen D Silberstein, Richard B Lipton, David W Dodick
OBJECTIVE: The prevalence, disability, progression, and treatment needs associated with chronic migraine (CM) mandate epidemiological, clinical, and basic research to better understand the clinical course of this disorder and to facilitate development of more effective therapies. Such efforts have been significantly impeded by lack of agreement within the headache specialist community of the most appropriate diagnostic criteria for CM. METHODS: This paper reviews the pertinent nosological literature and extensive field testing already performed...
July 2014: Headache
keyword
keyword
31141
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"