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https://www.readbyqxmd.com/read/29340595/clinical-impact-of-rotor-ablation-in-atrial-fibrillation-a-systematic-review
#1
Ramanathan Parameswaran, Aleksandr Voskoboinik, Alexandra Gorelik, Geoffrey Lee, Peter M Kistler, Prashanthan Sanders, Jonathan M Kalman
Aims: Rotor mapping and ablation have gained favour over the recent years as an emerging ablation strategy targeting drivers of atrial fibrillation (AF). Their efficacy, however, has been a topic of great debate with variable outcomes across centres. The aim of this study was to systematically review the recent medical literature to determine the medium-term outcomes of rotor ablation in patients with paroxysmal atrial fibrillation (PAF) and persistent atrial fibrillation (PeAF). Methods and results: A systematic search of the contemporary scientific literature (PubMed and EMBASE) was performed in August 2017...
January 11, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29340587/subclinical-device-detected-atrial-fibrillation-and-stroke-risk-a-systematic-review-and-meta-analysis
#2
Rajiv Mahajan, Tharani Perera, Adrian D Elliott, Darragh J Twomey, Sharath Kumar, Dian A Munwar, Kashif B Khokhar, Anand Thiyagarajah, Melissa E Middeldorp, Chrishan J Nalliah, Jeroen M L Hendriks, Jonathan M Kalman, Dennis H Lau, Prashanthan Sanders
Aims: To determine stroke risk in subclinical atrial fibrillation (AF) and temporal association between subclinical AF and stroke. Methods and results: Pubmed/Embase was searched for studies reporting stroke in subclinical AF in patients with cardiac implantable electronic devices (CIEDs). After exclusions, 11 studies were analysed. Of these seven studies reported prevalence of subclinical AF, two studies reported association between subclinical and clinical AF, seven studies reported stroke risk in subclinical AF, and five studies reported temporal relationship between subclinical AF and stroke...
January 10, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29338775/comparison-of-speckle-tracking-echocardiography-with-invasive-hemodynamics-for-the-detection-of-characteristic-cardiac-dysfunction-in-type-1-and-type-2-diabetic-rat-models
#3
Csaba Mátyás, Attila Kovács, Balázs Tamás Németh, Attila Oláh, Szilveszter Braun, Márton Tokodi, Bálint András Barta, Kálmán Benke, Mihály Ruppert, Bálint Károly Lakatos, Béla Merkely, Tamás Radovits
BACKGROUND: Measurement of systolic and diastolic function in animal models is challenging by conventional non-invasive methods. Therefore, we aimed at comparing speckle-tracking echocardiography (STE)-derived parameters to the indices of left ventricular (LV) pressure-volume (PV) analysis to detect cardiac dysfunction in rat models of type-1 (T1DM) and type-2 (T2DM) diabetes mellitus. METHODS: Rat models of T1DM (induced by 60 mg/kg streptozotocin, n = 8) and T2DM (32-week-old Zucker Diabetic Fatty rats, n = 7) and corresponding control animals (n = 5 and n = 8, respectively) were compared...
January 16, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29337286/estimation-of-parameters-for-plasma-glucose-regulation-in-type-2-diabetics-in-presence-of-meal
#4
Prova Biswas, Ashoke Sutradhar, Pallab Datta
In this study, the authors propose a methodology for the estimation of glucose masses in stomach (both in solid and liquid forms), intestine, plasma and tissue; insulin masses in portal vein, liver, plasma and interstitial fluid using only plasma glucose measurement. The proposed methodology fuses glucose-insulin homoeostasis model (in the presence of meal intake) and plasma glucose measurement with a Bayesian non-linear filter. Uncertainty of the model over individual variations has been incorporated by adding process noise to the homoeostasis model...
February 2018: IET Systems Biology
https://www.readbyqxmd.com/read/29335642/controlled-dynamic-screening-of-excitonic-complexes-in-2d-semiconductors
#5
Andrey R Klots, Benjamin Weintrub, Dhiraj Prasai, Daniel Kidd, Kalman Varga, Kirill A Velizhanin, Kirill I Bolotin
We report a combined theoretical/experimental study of dynamic screening of excitons in media with frequency-dependent dielectric functions. We develop an analytical model showing that interparticle interactions in an exciton are screened in the range of frequencies from zero to the characteristic binding energy depending on the symmetries and transition energies of that exciton. The problem of the dynamic screening is then reduced to simply solving the Schrodinger equation with an effectively frequency-independent potential...
January 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29332257/kynurenic-acid-and-its-derivatives-are-able-to-modulate-the-adhesion-and-locomotion-of-brain-endothelial-cells
#6
Eszter Lajkó, Bernadett Tuka, Ferenc Fülöp, István Krizbai, József Toldi, Kálmán Magyar, László Vécsei, László Kőhidai
The neuroprotective actions of kynurenic acid (KYNA) and its derivatives in several neurodegenerative disorders [characterized by damage to the cerebral endothelium and to the blood-brain barrier (BBB)] are well established. Cell-extracellular matrix (ECM) adhesion is supposedly involved in recovery of impaired cerebral endothelium integrity (endothelial repair). The present work aimed to investigate the effects of KYNA and its synthetic derivatives on cellular behaviour (e.g. adhesion and locomotion) and on morphology of the GP8 rat brain endothelial cell line, modeling the BBB endothelium...
January 13, 2018: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29330195/dicer1-gene-mutations-in-endocrine-tumors
#7
Michael Solarski, Fabio Rotondo, William Foulkes, John R Priest, Luis V Syro, Henriett Butz, Michael Cusimano, Kalman Kovacs
In this review, the importance of the DICER1 gene in the function of endocrine cells is discussed. There is conclusive evidence that DICER1 mutations play a crucial role in the development, progression, cell proliferation, therapeutic responsiveness and behavior of several endocrine tumors. We review the literature of DICER1 gene mutations in thyroid, parathyroid, pituitary, pineal gland, endocrine pancreas, paragangliomas, medullary, adrenocortical, ovarian, and testicular tumors. Although significant progress has been made during the last few years, much more work is needed to fully understand the significance of DICER1 mutations...
January 12, 2018: Endocrine-related Cancer
https://www.readbyqxmd.com/read/29329243/characteristics-of-beidou-navigation-satellite-system-multipath-and-its-mitigation-method-based-on-kalman-filter-and-rauch-tung-striebel-smoother
#8
Qiuzhao Zhang, Wei Yang, Shubi Zhang, Xin Liu
Global Navigation Satellite System (GNSS) carrier phase measurement for short baseline meets the requirements of deformation monitoring of large structures. However, the carrier phase multipath effect is the main error source with double difference (DD) processing. There are lots of methods to deal with the multipath errors of Global Position System (GPS) carrier phase data. The BeiDou navigation satellite System (BDS) multipath mitigation is still a research hotspot because the unique constellation design of BDS makes it different to mitigate multipath effects compared to GPS...
January 12, 2018: Sensors
https://www.readbyqxmd.com/read/29321627/publisher-correction-a-cdk1-gradient-guides-surface-contraction-waves-in-oocytes
#9
Johanna Bischof, Christoph A Brand, Kálmán Somogyi, Imre Májer, Sarah Thome, Masashi Mori, Ulrich S Schwarz, Péter Lénárt
A Supplementary Information file from a different paper was inadvertently published with the original version of this Article. This file was replaced with the correct Supplementary Information file on 24 October 2017.
January 10, 2018: Nature Communications
https://www.readbyqxmd.com/read/29321055/trends-and-correlates-of-overweight-obesity-in-czech-adolescents-in-relation-to-family-socioeconomic-status-over-a-12-year-study-period-2002-2014
#10
Erik Sigmund, Petr Badura, Dagmar Sigmundová, Jaroslava Voráčová, Jiří Zacpal, Michal Kalman, Jan Pavelka, Jana Vokacová, Vladimír Jr Hobza, Zdenek Hamrik
BACKGROUND: This study examined a) trends in overweight/obesity, moderate-to-vigorous physical activity (MVPA), and screen time (ST) among Czech adolescents over a 12-year study period (2002-2014) in relation to family affluence (FA) and b) correlates of adolescent overweight/obesity from different FA categories. METHODS: A nationally representative sample of 18,250 adolescents (51.4% girls) aged 10.5-16.5 years was drawn from the Czech Health Behaviour in School-aged Children questionnaire-based surveys in 2002, 2006, 2010, and 2014...
January 10, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29317693/past-visual-experiences-weigh-in-on-body-size-estimation
#11
Joanna Alexi, Dominique Cleary, Kendra Dommisse, Romina Palermo, Nadine Kloth, David Burr, Jason Bell
Body size is a salient marker of physical health, with extremes implicated in various mental and physical health issues. It is therefore important to understand the mechanisms of perception of body size of self and others. We report a novel technique we term the bodyline, based on the numberline technique in numerosity studies. One hundred and three young women judged the size of sequentially presented female body images by positioning a marker on a line, delineated with images of extreme sizes. Participants performed this task easily and well, with average standard deviations less than 6% of the total scale...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29315382/safety-and-long-term-effectiveness-of-paroxysmal-atrial-fibrillation-ablation-with-a-contact-force-sensing-catheter-real-world-experience-from-a-prospective-multicentre-observational-cohort-registry
#12
Tom De Potter, Hugo Van Herendael, Richard Balasubramaniam, Matthew Wright, Sharad C Agarwal, Prashanthan Sanders, Yaariv Khaykin, Decebal-Gabriel Latcu, Philippe Maury, Antonio Pani, John Hayes, Jonathan Kalman, Pablo Nery, Edward Duncan
Aims: Real-time contact force (CF)-sensing radiofrequency ablation catheter for treatment of paroxysmal atrial fibrillation (PAF) allows optimization of electrode-tissue contact, which correlates with long-term success. This prospective, multicentre observational registry assessed the real-world clinical effectiveness of a CF-sensing catheter for ablation of drug-refractory PAF. Methods and results: Patients were followed-up at 3, 6, and 12 months after ablation...
January 4, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29315267/experimental-evaluation-of-uwb-indoor-positioning-for-sport-postures
#13
Matteo Ridolfi, Stef Vandermeeren, Jense Defraye, Heidi Steendam, Joeri Gerlo, Dirk De Clercq, Jeroen Hoebeke, Eli De Poorter
Radio frequency (RF)-based indoor positioning systems (IPSs) use wireless technologies (including Wi-Fi, Zigbee, Bluetooth, and ultra-wide band (UWB)) to estimate the location of persons in areas where no Global Positioning System (GPS) reception is available, for example in indoor stadiums or sports halls. Of the above-mentioned forms of radio frequency (RF) technology, UWB is considered one of the most accurate approaches because it can provide positioning estimates with centimeter-level accuracy. However, it is not yet known whether UWB can also offer such accurate position estimates during strenuous dynamic activities in which moves are characterized by fast changes in direction and velocity...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29315256/a-novel-attitude-determination-system-aided-by-polarization-sensor
#14
Wei Zhi, Jinkui Chu, Jinshan Li, Yinlong Wang
This paper aims to develop a novel attitude determination system aided by polarization sensor. An improved heading angle function is derived using the perpendicular relationship between directions of E-vector of linearly polarized light and solar vector in the atmospheric polarization distribution model. The Extended Kalman filter (EKF) with quaternion differential equation as a dynamic model is applied to fuse the data from sensors. The covariance functions of filter process and measurement noises are deduced in detail...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29313728/the-potential-of-currently-unavailable-herpes-virus-vaccines
#15
Július Rajcáni, Ferenc Bánáti, Kálmán Szenthe, Susan Szathmary
Despite overwhelming experimental work, there are no licensed vaccines against the most frequent Alphaherpesviruses, namely herpes simplex virus 1 and 2 (HSV1 and 2) nor against the Epstein-Barr virus (EBV), a member of the subfamily Gammaherpesvirus. Areas covered: Since the DNAs of both HSVs reside in the regional sensory ganglia in a latent state (i.e. as circularized episomal molecules), a corresponding vaccine might be useful for immunotherapy rather than prevention of primary infection. Here we describe the design of a purified subunit vaccine (a mix of at least 3 glycoproteins) as well as the preparation and efficacy of a recombinant fusion protein consisting of the gD ectodomain from our domestic attenuated HSV1 strain HSZP...
January 9, 2018: Expert Review of Vaccines
https://www.readbyqxmd.com/read/29305190/online-wavelet-complementary-velocity-estimator
#16
Paolo Righettini, Roberto Strada, Ehsan KhademOlama, Shirin Valilou
In this paper, we have proposed a new online Wavelet Complementary velocity Estimator (WCE) over position and acceleration data gathered from an electro hydraulic servo shaking table. This is a batch estimator type that is based on the wavelet filter banks which extract the high and low resolution of data. The proposed complementary estimator combines these two resolutions of velocities which acquired from numerical differentiation and integration of the position and acceleration sensors by considering a fixed moving horizon window as input to wavelet filter...
January 2, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29302181/medical-students-attitudes-toward-torture-revisited
#17
Krista Dubin, Andrew R Milewski, Joseph Shin, Thomas P Kalman
This paper reports the findings of a survey of medical students' attitudes toward torture and discusses variables that may correlate with those attitudes. In late 2016, 483 enrolled medical and MD-PhD students at the Weill Cornell Medical College received an anonymous, institutional review board-approved survey that included questions about torture and its effectiveness, demographic questions, inquiries about personal experiences of harassment or discrimination, and questions regarding engagement in human rights activities...
December 2017: Health and Human Rights
https://www.readbyqxmd.com/read/29300358/accurate-3d-positioning-for-a-mobile-platform-in-non-line-of-sight-scenarios-based-on-imu-magnetometer-sensor-fusion
#18
Hendrik Hellmers, Zakaria Kasmi, Abdelmoumen Norrdine, Andreas Eichhorn
In recent years, a variety of real-time applications benefit from services provided by localization systems due to the advent of sensing and communication technologies. Since the Global Navigation Satellite System (GNSS) enables localization only outside buildings, applications for indoor positioning and navigation use alternative technologies. Ultra Wide Band Signals (UWB), Wireless Local Area Network (WLAN), ultrasonic or infrared are common examples. However, these technologies suffer from fading and multipath effects caused by objects and materials in the building...
January 4, 2018: Sensors
https://www.readbyqxmd.com/read/29296580/managing-cross-talk-between-a-subcutaneous-implantable-cardioverter-defibrillator-and-a-dual-chamber-unipolar-pacemaker-system
#19
Konstantinos Kossidas, Richard Kalman, William P Follis, Joshua M Cooper
No abstract text is available yet for this article.
December 2017: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/29289051/mathematical-foundations-of-hybrid-data-assimilation-from-a-synchronization-perspective
#20
Stephen G Penny
The state-of-the-art data assimilation methods used today in operational weather prediction centers around the world can be classified as generalized one-way coupled impulsive synchronization. This classification permits the investigation of hybrid data assimilation methods, which combine dynamic error estimates of the system state with long time-averaged (climatological) error estimates, from a synchronization perspective. Illustrative results show how dynamically informed formulations of the coupling matrix (via an Ensemble Kalman Filter, EnKF) can lead to synchronization when observing networks are sparse and how hybrid methods can lead to synchronization when those dynamic formulations are inadequate (due to small ensemble sizes)...
December 2017: Chaos
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