Read by QxMD icon Read

Lawrence Lenke

Patrick Knott, Peter Sturm, Baron Lonner, Patrick Cahill, Marcel Betsch, Richard McCarthy, Michael Kelly, Lawrence Lenke, Randal Betz
INTRODUCTION: In pediatric spinal deformity the gold standard for curve surveillance remains standing full-column radiographs, but repeated exposure to ionizing radiation motivates us to look for nonradiographic solutions. This study tests a modern system of surface topography (ST) to determine whether it is reliable and reproducible. METHODS: Patients from 6 pediatric spinal deformity clinics were recruited for enrollment. Inclusion criteria were age 8-18; diagnosis of scoliosis measuring ≥10 and <50 degrees or increased kyphosis of ≥45 degrees...
March 2016: Spine Deformity
Jeffrey L Gum, Lawrence G Lenke, David Bumpass, Johnny Zhao, Patrick Sugrue, Isaac Karikari, Ra'Kerry Rahman, Leah Y Carreon
STUDY DESIGN: Propensity-matched case control. OBJECTIVES: To compare the perioperative complication rate between single- and two-stage posterior-only VCRs (2-pVCR). SUMMARY OF BACKGROUND DATA: A vertebral column resection (VCR) for severe spinal deformity is a technically challenging and lengthy procedure with a potentially high complication rate. Planned staging has an advantage of distributing operative time into 2 smaller, more manageable, intervals...
March 2016: Spine Deformity
David L Skaggs, Derek A Seehausen, Kent T Yamaguchi, Raymond J Hah, Margaret L Wright, David B Bumpass, Han J Kim, Lindsay M Andras, Michael G Vitale, Lawrence G Lenke
STUDY DESIGN: Multicenter, retrospective cohort study. OBJECTIVES: The purpose of this study is to determine how the amount of residual lowest instrumented vertebra (LIV) tilt correlates with radiographic measurements. SUMMARY OF BACKGROUND DATA: When performing a selective thoracic posterior spinal fusion for adolescent idiopathic scoliosis (AIS), the LIV may be tilted into the lumbar curve or made horizontal. METHODS: This is a multicenter retrospective study of 33 consecutive patients with AIS, Lenke types 1 to 4, lumbar modifier C, and a minimum follow-up of 2 years, who underwent selective thoracic posterior spinal fusions...
March 2016: Spine Deformity
Ho-Joong Kim, Kyoung-Tak Kang, Sung-Cheol Park, Oh-Hyo Kwon, Juhyun Son, Bong-Soon Chang, Choon-Ki Lee, Jin S Yeom, Lawrence G Lenke
BACKGROUND CONTEXT: There have been conflicting results on the surgical outcome of lumbar fusion surgery using two different techniques: robot-assisted pedicle screw fixation and conventional freehand technique. In addition, there have been no studies about the biomechanical issues between both techniques. PURPOSE: This study aimed to investigate the biomechanical properties in terms of stress at adjacent segments using robot-assisted pedicle screw insertion technique (robot-assisted, minimally invasive posterior lumbar interbody fusion, Rom-PLIF) and freehand technique (conventional, freehand, open approach, posterior lumbar interbody fusion, Cop-PLIF) for instrumented lumbar fusion surgery...
November 17, 2016: Spine Journal: Official Journal of the North American Spine Society
Mladen Djurasovic, Steven D Glassman, Daniel J Sucato, Lawrence G Lenke, Charles H Crawford, Leah Y Carreon
STUDY DESIGN: Longitudinal cohort. OBJECTIVE: To investigate whether patients with painful adolescent idiopathic scoliosis experience pain relief with surgical treatment. SUMMARY OF BACKGROUND DATA: Adolescent idiopathic scoliosis (AIS) was previously thought to be a painless condition, but recent studies have shown that a significant proportion of patients have pain. Little information is available regarding pain relief with surgical treatment for AIS...
November 15, 2016: Spine
Todd M Chapman, Christine R Baldus, Jon D Lurie, Steven D Glassman, Frank J Schwab, Christopher I Shaffrey, Virginie Lafage, Oheneba Boachie-Adjei, Han J Kim, Justin S Smith, Charles H Crawford, Lawrence G Lenke, Jacob M Buchowski, Charles Edwards, Tyler Koski, Stefan Parent, Stephen Lewis, Daniel G Kang, Jamal McClendon, Lionel Metz, Lukas P Zebala, Michael P Kelly, Kevin F Spratt, Keith H Bridwell
STUDY DESIGN: Prospective, cross-sectional study. OBJECTIVE: The aim of the study was to determine which radiographic parameters drive patient-reported outcomes (PROs) in primary presentation adult symptomatic lumbar scoliosis (ASLS). SUMMARY OF BACKGROUND DATA: Previous literature suggests correlations between PROs and sagittal plane deformity (sagittal vertical axis [SVA], pelvic incidence-lumbar lordosis [PI-LL] mismatch, pelvic tilt [PT])...
November 15, 2016: Spine
Leo Fradet, Xiaoyu Wang, Lawrence G Lenke, Carl-Eric Aubin
BACKGROUND: Proximal junctional failure is a severe proximal junctional complication following adult spinal instrumentation and involving acute proximal junctional kyphotic deformity, mechanical failure at the upper instrumented vertebra or just above, and/or proximal junctional osseoligamentous disruption. Clinical studies have identified potential risk factors, but knowledge on their biomechanics is still lacking for addressing the proximal junctional failure issues. The objective of this study was to develop comprehensive computational modeling and simulation techniques to investigate proximal junctional failure...
November 2016: Clinical Biomechanics
Yong-Chan Kim, Lawrence G Lenke, Seon-Jong Lee, Jeffrey L Gum, Sirichai Wilartratsami, Kathy M Blanke
PURPOSE: Our study aimed to confirm the correlation between the Cranial Sagittal Vertical Axis (CrSVA) and patient-reported outcomes and to compare clinical correlation between CrSVA and C7 SVA in adult spinal deformity (ASD) patients. METHODS: 108 consecutive ASD patients were evaluated using the EOS(®) 2D/3D radio-imaging device. A vertical plumb line from the cranial center was utilized to measure the distance to the posterior corner of S1 (CrSVA-S), and to the centers of the hip (CrSVA-H), the knee (CrSVA-K), and ankle (CrSVA-A), as well as measuring the standard C7 SVA...
October 14, 2016: European Spine Journal
Jeffrey L Gum, Leah Y Carreon, Jacob M Buchowski, Lawrence G Lenke, Steven D Glassman
BACKGROUND: Increased awareness regarding the importance of the sagittal spinal profile has led to more aggressive correction of sagittal malalignment. The utilization trends of pedicle subtraction osteotomy (PSO) for sagittal plane correction in spinal deformity surgery have not been well characterized. METHODS: A commercially available database (PearlDiver, Inc) was queried for both Private Payor and 5 % Medicare claims from 2008 to 2011. Revision and clarification of the coding guidelines for PSO were introduced in 2008...
2016: Scoliosis and Spinal Disorders
Joshua S Murphy, Vidyadhar V Upasani, Burt Yaszay, Tracey P Bastrom, Carrie E Bartley, Amer Samdani, Lawrence G Lenke, Peter O Newton
STUDY DESIGN: Retrospective review of prospectively collected dataObjective: To determine whether the last substantially touched vertebra (LSTV) is a valid lowest instrumented vertebra (LIV) for both Lenke 1 and 2 curve patterns with AR lumbar modifiers,and to identify pre-operative risk factors of distal adding-on. SUMMARY OF BACKGROUND: Previous studies have recommended selecting the LSTV as the LIV for Lenke 1AR curves (main thoracic curve with 'A' lumbar modifier and L4 tilt to the right (thoracic overhang / King type IV curve)...
July 7, 2016: Spine
Ammar H Hawasli, Jodie Chang, Chester K Yarbrough, Karen Steger-May, Lawrence G Lenke, Ian G Dorward
BACKGROUND CONTEXT: Spine surgeons must correlate clinical presentation with radiographic findings in a patient-tailored approach. Despite the prevalence of adult degenerative scoliosis (ADS), there are few radiographic markers to predict the presence of radiculopathy. Emerging data suggest that spondylolisthesis, obliquity, foraminal stenosis, and curve concavity may be associated with radiculopathy in ADS. PURPOSE: The purpose of this study was to determine if radicular pain in ADS is associated with reduced interpedicular heights (IPHs) as measured on routine radiographs...
September 2016: Spine Journal: Official Journal of the North American Spine Society
Yong-Chan Kim, Lawrence G Lenke, Keith H Bridwell, Seung-Jae Hyun, Ki-Han You, Young-Woo Kim, Ho-Guen Chang, Michael P Kelly, Linda A Koester, Kathy M Blanke, David B Bumpass
STUDY DESIGN: A retrospective cohort study. OBJECTIVES: The aim of this study was to evaluate radiographic and patient-reported outcomes at minimum 2 years after revision surgery for proximal junctional kyphosis (PJK), correlating these results with PJK etiology. SUMMARY OF BACKGROUND DATA: There are no studies detailing the results of revision surgery for PJK following posterior segmental instrumentation. METHODS: Thirty-two consecutive patients treated with revision surgery after PJK above posterior fusions (25 women/7 men, average age at surgery 60...
December 15, 2016: Spine
Sravisht Iyer, Lawrence G Lenke, Venu M Nemani, Michael Fu, Grant D Shifflett, Todd J Albert, Brenda A Sides, Lionel N Metz, Matthew E Cunningham, Han Jo Kim
STUDY DESIGN: Cross-Sectional Cohort Study OBJECTIVE.: To describe age-stratified normative values of novel occipitocervical, cervical, and cervicothoracic alignment parameters. SUMMARY OF BACKGROUND DATA: Full-body radiographic images obtained without stitching or vertical distortion represent an ideal method to evaluate occipitocervical alignment and horizontal gaze. METHODS: One hundred twenty adults with no back or neck symptoms were recruited...
December 1, 2016: Spine
Sravisht Iyer, Lawrence G Lenke, Venu M Nemani, Todd J Albert, Brenda A Sides, Lionel Nicholas Metz, Matthew E Cunningham, Han Jo Kim
STUDY DESIGN: Cross-sectional cohort study. OBJECTIVE: Describe age-stratified normative values of traditional and novel sagittal alignment parameters. SUMMARY OF BACKGROUND DATA: Full-body radiographic techniques can capture coronal and sagittal standing images from the occiput to the foot without stitching or vertical distortion. This provides an ideal method to evaluate measures of global alignment. METHODS: Adults with no back or neck symptoms were recruited...
December 1, 2016: Spine
Steven L Bokshan, Jakub Godzik, Jonathan Dalton, Jennifer Jaffe, Lawrence G Lenke, Michael P Kelly
BACKGROUND CONTEXT: The non-response rates are as high as 20% to 50% after 5 years of follow-up in adult spinal deformity (ASD) surgery. Minimizing loss to follow-up is essential to protect the quality of data in long-term studies. Phone and internet administration of outcomes instruments has grown in popularity and has been found to not only provide a convenient way of collecting data, but also show improved response rates. PURPOSE: The study aimed to examine the reliability of the revised Scoliosis Research Society-22 (SRS-22r) and the Oswestry Disability Index (ODI) questionnaires in ASD patients when administered by telephone...
September 2016: Spine Journal: Official Journal of the North American Spine Society
Xiao-Bin Wang, Lawrence G Lenke, Earl Thuet, Kathy Blanke, Linda A Koester, Michael Roth
STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: To assess the value of the deformity angular ratio (DAR, maximum Cobb measurement divided by number of vertebrae involved) in evaluating the severity of spinal deformity, and predicting the risk of neurologic deficit in posterior vertebral column resection (PVCR). SUMMARY OF BACKGROUND DATA: Although the literature has demonstrated that PVCR in spinal deformity patients has achieved excellent outcomes, it is still high risk neurologically...
September 15, 2016: Spine
Barry L Raynor, Anne M Padberg, Lawrence G Lenke, Keith H Bridwell, K Daniel Riew, Jacob M Buchowski, Scott J Luhmann
STUDY DESIGN: Retrospective. OBJECTIVE: The purpose was to categorize and evaluate intraoperative monitoring (IOM) failure to detect neurologic deficits occurring during spinal surgery. SUMMARY OF BACKGROUND DATA: The efficacy of spinal cord/nerve root monitoring regarding undetected neurologic deficits is examined in a large, single institution series involving all levels of the spinal column and all spinal surgical procedures. METHODS: Multimodality IOM included somatosensory-evoked potentials (SSEPs), descending neurogenic-evoked potentials (DNEPs), transcranial motor-evoked potentials (MEPs), dermatomal somatosensory-evoked potentials (DSEPs), and spontaneous and triggered electromyography (spEMG, trgEMG)...
September 2016: Spine
Melvin C Makhni, Jon-Michael E Caldwell, Comron Saifi, Charla R Fischer, Ronald A Lehman, Lawrence G Lenke, Francis Y Lee
Autograft, while currently the gold standard for bone grafting, has several significant disadvantages including limited supply, donor site pain, hematoma formation, nerve and vascular injury, and fracture. Bone allografts have their own disadvantages including reduced osteoinductive capability, lack of osteoprogenitor cells, immunogenicity and risk of disease transmission. Thus demand exists for tissue-engineered constructs that can produce viable bone while avoiding the complications associated with human tissue grafts...
March 2016: Regenerative Medicine
Lawrence G Lenke, Michael G Fehlings, Christopher I Shaffrey, Kenneth M C Cheung, Leah Carreon, Mark B Dekutoski, Frank J Schwab, Oheneba Boachie-Adjei, Khaled M Kebaish, Christopher P Ames, Yong Qiu, Yukihiro Matsuyama, Benny T Dahl, Hossein Mehdian, Ferran Pellisé-Urquiza, Stephen J Lewis, Sigurd H Berven
STUDY DESIGN: Prospective, multicenter, international observational study. OBJECTIVE: To evaluate motor neurologic outcomes in patients undergoing surgery for complex adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: The neurologic outcomes after surgical correction for ASD have been reported with significant variability and have not been measured as a primary endpoint in any prospective, multicenter, observational study. METHODS: The primary outcome measure was the change in American Spinal Injury Association (ASIA) Lower Extremity Motor Scores (LEMS) obtained preoperatively, and at hospital discharge, 6 weeks and 6 months postoperatively...
February 2016: Spine
Brian J Neuman, Christine Baldus, Lukas P Zebala, Michael P Kelly, Christopher Shaffrey, Charles Edwards, Tyler Koski, Frank Schwab, Steven Glassman, Stefan Parent, Stephen Lewis, Lawrence G Lenke, Jacob M Buchowski, Justin S Smith, Charles H Crawford, Han Jo Kim, Virginia Lafage, Jon Lurie, Leah Carreon, Keith H Bridwell
STUDY DESIGN: A prospective study with randomized and observational cohorts. OBJECTIVE: The aim of this study was to determine baseline variables affecting adult symptomatic lumbar scoliosis (ASLS) decision making to participate in randomization (RAND), observational nonsurgical (OBS-NS), or observational surgical (OBS-S) cohorts. SUMMARY OF BACKGROUND DATA: Multiple factors play a key role in a patient's decision to be randomized or to choose an OBS-NS or OBS-S course for ASLS...
March 2016: Spine
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"