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Lawrence Lenke

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https://www.readbyqxmd.com/read/28589303/three-types-of-sagittal-alignment-regarding-compensation-in-asymptomatic-adults-the-contribution-of-the-spine-and-lower-limbs
#1
Hongda Bao, Renaud Lafage, Barthelemy Liabaud, Jonathan Elysée, Bassel G Diebo, Gregory Poorman, Cyrus Jalai, Peter Passias, Aaron Buckland, Shay Bess, Thomas Errico, Lawrence G Lenke, Munish Gupta, Han Jo Kim, Frank Schwab, Virginie Lafage
PURPOSE: A comprehensive understanding of normative sagittal profile is necessary for adult spinal deformity. Roussouly described four sagittal alignment types based on sacral slope, lumbar lordosis, and location of lumbar apex. However, the lower limb, a newly described component of spinal malalignment compensation, is missing from this classification. This study aims to propose a full-body sagittal profile classification in an asymptomatic population based on full-body imaging. METHODS: This is a retrospective analysis of a prospective single-center study of 116 asymptomatic volunteers...
June 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28475019/retrospective-analysis-underestimates-neurological-deficits-in-complex-spinal-deformity-surgery-a-scoli-risk-1-study
#2
Michael P Kelly, Lawrence G Lenke, Jakub Godzik, Ferran Pellise, Christopher I Shaffrey, Justin S Smith, Stephen J Lewis, Christopher P Ames, Leah Y Carreon, Michael G Fehlings, Frank Schwab, Adam L Shimer
OBJECTIVE The authors conducted a study to compare neurological deficit rates associated with complex adult spinal deformity (ASD) surgery when recorded in retrospective and prospective studies. Retrospective studies may underreport neurological deficits due to selection, detection, and recall biases. Prospective studies are expensive and more difficult to perform, but they likely provide more accurate estimates of new neurological deficit rates. METHODS New neurological deficits were recorded in a prospective study of complex ASD surgeries (pSR1) with a defined outcomes measure (decrement in American Spinal Injury Association lower-extremity motor score) for neurological deficits...
May 5, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28441310/a-dose-response-curve-for-a-gram-negative-spinal-implant-infection-model-in-rabbits
#3
Joseph L Laratta, Jamal N Shillingford, Nathan Hardy, Ronald A Lehman, Lawrence G Lenke, K Daniel Riew
STUDY DESIGN: Randomized complete block animal spinal implant infection model with internal control. OBJECTIVE: To develop a spinal implant animal infection model to simulate postoperative gram-negative wound infection. SUMMARY OF BACKGROUND DATA: Implant-associated surgical site infections (SSI) remain a dreaded complication of spinal surgery. Currently, over 30% of all spine SSIs are secondary to gram-negative bacteria. Traditional animal models have utilized gram-positive inoculums to simulate postoperative infection, but there exists no model in the literature for gram-negative infection in the setting of spinal instrumentation...
April 24, 2017: Spine
https://www.readbyqxmd.com/read/28399544/intrawound-tobramycin-powder-eradicates-surgical-wound-contamination-an-in-vivo-rabbit-study
#4
Joseph L Laratta, Jamal N Shillingford, Nathan Hardy, Joseph M Lombardi, Comron Saifi, Alexander Romanov, Lawrence G Lenke, Ronald A Lehman, K Daniel Riew
STUDY DESIGN: Therapeutic anti-infective trial in rabbitsOBJECTIVE.: The purpose of the present study was to assess the efficacy of intrawound tobramycin powder in terms of eradicating a known bacterial contamination in an Escherichia coli infected rabbit spinal implantation model. SUMMARY OF BACKGROUND DATA: Implant-associated surgical site infections (SSI) remain a dreaded complication of spinal surgery. Currently, over 30% of all spine SSIs are secondary to gram-negative bacteria...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28350940/recent-and-emerging-advances-in-spinal-deformity
#5
Justin S Smith, Christopher I Shaffrey, Shay Bess, Mohammed F Shamji, Darrel Brodke, Lawrence G Lenke, Michael G Fehlings, Virginie Lafage, Frank Schwab, Alexander R Vaccaro, Christopher P Ames
BACKGROUND: Over the last several decades, significant advances have occurred in the assessment and management of spinal deformity. OBJECTIVE: The primary focus of this narrative review is on recent advances in adult thoracic, thoracolumbar, and lumbar deformities, with additional discussions of advances in cervical deformity and pediatric deformity. METHODS: A review of recent literature was conducted. RESULTS: Advances in adult thoracic, thoracolumbar, and lumbar deformities reviewed include the growing applications of stereoradiography, development of new radiographic measures and improved understanding of radiographic alignment objectives, increasingly sophisticated tools for radiographic analysis, strategies to reduce the occurrence of common complications, and advances in minimally invasive techniques...
March 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28323715/the-safety-and-strength-of-a-novel-medial-partial-nonthreaded-pedicle-screw-a-cadaveric-and-biomechanical-investigation
#6
Mun Keong Kwan, Chris Yin Wei Chan, Lim Beng Saw, Shanmugam Rukmanikanthan, Lawrence G Lenke
STUDY DESIGN: Cadaveric and biomechanical study. OBJECTIVE: The aim of this study was to assess the safety and pullout strength of medial, partial nonthreaded thoracic pedicle screws compared with conventional screws. SUMMARY OF BACKGROUND DATA: The perforation rate of the pedicle screws has been reported as high as 41%. Nerve injury and irritation can result from the compression of malpositioned screw on neural structures. METHODS: Ten fresh cadavers were studied...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28259266/predictors-of-health-related-quality-of-life-after-complex-adult-spinal-deformity-surgery-a-scoli-risk-1-secondary-analysis
#7
Leah Y Carreon, Steven D Glassman, Christopher I Shaffrey, Michael G Fehlings, Benny Dahl, Christopher P Ames, Yukihiro Matsuyama, Yong Qiu, Hossein Mehdian, Kenneth M C Cheung, Frank J Schwab, Ferran Pellisé, Khaled M Kebaish, Lawrence G Lenke
STUDY DESIGN: Longitudinal cohort. OBJECTIVES: To identify variables that predict 2-year Short Form-36 Physical Composite Summary Score (SF-36PCS) and the Scoliosis Research Society-22R (SRS22-R) Total score after surgery for complex adult spinal deformity. SUMMARY OF BACKGROUND DATA: Increasingly, treatment effectiveness is assessed by the extent to which the procedure improves a patient's health-related quality of life (HRQOL). This is especially true in patients with complex adult spinal deformity...
March 2017: Spine Deformity
https://www.readbyqxmd.com/read/28207660/predictors-of-distal-adding-on-in-thoracic-major-curves-with-ar-lumbar-modifiers
#8
Joshua S Murphy, Vidyadhar V Upasani, Burt Yaszay, Tracey P Bastrom, Carrie E Bartley, Amer Samdani, Lawrence G Lenke, Peter O Newton
STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: To determine whether the last substantially touched vertebra (LSTV) is a valid lowest instrumented vertebra (LIV) for both Lenke 1 and 2 curve patterns with AR lumbar modifiers, and to identify preoperative risk factors of distal adding-on. SUMMARY OF BACKGROUND DATA: Previous studies have recommended selecting the LSTV as the LIV for Lenke 1AR curves (main thoracic curve with A lumbar modifier and L4 tilt to the right (thoracic overhang/King type IV curve)...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/27927552/multicenter-comparison-of-3d-spinal-measurements-using-surface-topography-with-those-from-conventional-radiography
#9
Patrick Knott, Peter Sturm, Baron Lonner, Patrick Cahill, Marcel Betsch, Richard McCarthy, Michael Kelly, Lawrence Lenke, Randal Betz
INTRODUCTION: In pediatric spinal deformity the gold standard for curve surveillance remains standing full-column radiographs, but repeated exposure to ionizing radiation motivates us to look for nonradiographic solutions. This study tests a modern system of surface topography (ST) to determine whether it is reliable and reproducible. METHODS: Patients from 6 pediatric spinal deformity clinics were recruited for enrollment. Inclusion criteria were age 8-18; diagnosis of scoliosis measuring ≥10 and <50 degrees or increased kyphosis of ≥45 degrees...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927545/does-planned-staging-for-posterior-only-vertebral-column-resections-in-spinal-deformity-surgery-increase-perioperative-complications
#10
Jeffrey L Gum, Lawrence G Lenke, David Bumpass, Johnny Zhao, Patrick Sugrue, Isaac Karikari, Ra'Kerry Rahman, Leah Y Carreon
STUDY DESIGN: Propensity-matched case control. OBJECTIVES: To compare the perioperative complication rate between single- and two-stage posterior-only VCRs (2-pVCR). SUMMARY OF BACKGROUND DATA: A vertebral column resection (VCR) for severe spinal deformity is a technically challenging and lengthy procedure with a potentially high complication rate. Planned staging has an advantage of distributing operative time into 2 smaller, more manageable, intervals...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927544/assessment-of-lowest-instrumented-vertebra-tilt-on-radiographic-measurements-in-lenke-c-modifier-curves-undergoing-selective-thoracic-fusion-in-adolescent-idiopathic-scoliosis
#11
David L Skaggs, Derek A Seehausen, Kent T Yamaguchi, Raymond J Hah, Margaret L Wright, David B Bumpass, Han J Kim, Lindsay M Andras, Michael G Vitale, Lawrence G Lenke
STUDY DESIGN: Multicenter, retrospective cohort study. OBJECTIVES: The purpose of this study is to determine how the amount of residual lowest instrumented vertebra (LIV) tilt correlates with radiographic measurements. SUMMARY OF BACKGROUND DATA: When performing a selective thoracic posterior spinal fusion for adolescent idiopathic scoliosis (AIS), the LIV may be tilted into the lumbar curve or made horizontal. METHODS: This is a multicenter retrospective study of 33 consecutive patients with AIS, Lenke types 1 to 4, lumbar modifier C, and a minimum follow-up of 2 years, who underwent selective thoracic posterior spinal fusions...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27867080/biomechanical-advantages-of-robot-assisted-pedicle-screw-fixation-in-posterior-lumbar-interbody-fusion-compared-with-freehand-technique-in-a-prospective-randomized-controlled-trial-perspective-for-patient-specific-finite-element-analysis
#12
RANDOMIZED CONTROLLED TRIAL
Ho-Joong Kim, Kyoung-Tak Kang, Sung-Cheol Park, Oh-Hyo Kwon, Juhyun Son, Bong-Soon Chang, Choon-Ki Lee, Jin S Yeom, Lawrence G Lenke
BACKGROUND CONTEXT: There have been conflicting results on the surgical outcome of lumbar fusion surgery using two different techniques: robot-assisted pedicle screw fixation and conventional freehand technique. In addition, there have been no studies about the biomechanical issues between both techniques. PURPOSE: This study aimed to investigate the biomechanical properties in terms of stress at adjacent segments using robot-assisted pedicle screw insertion technique (robot-assisted, minimally invasive posterior lumbar interbody fusion, Rom-PLIF) and freehand technique (conventional, freehand, open approach, posterior lumbar interbody fusion, Cop-PLIF) for instrumented lumbar fusion surgery...
May 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27851662/improvement-in-srs22r-pain-scores-after-surgery-for-adolescent-idiopathic-scoliosis
#13
Mladen Djurasovic, Steven D Glassman, Daniel J Sucato, Lawrence G Lenke, Charles H Crawford, Leah Y Carreon
STUDY DESIGN: Longitudinal cohort. OBJECTIVE: To investigate whether patients with painful adolescent idiopathic scoliosis experience pain relief with surgical treatment. SUMMARY OF BACKGROUND DATA: Adolescent idiopathic scoliosis (AIS) was previously thought to be a painless condition, but recent studies have shown that a significant proportion of patients have pain. Little information is available regarding pain relief with surgical treatment for AIS...
November 15, 2016: Spine
https://www.readbyqxmd.com/read/27831984/baseline-patient-reported-outcomes-correlate-weakly-with-radiographic-parameters-a-multicenter-prospective-nih-adult-symptomatic-lumbar-scoliosis-study-of-286-patients
#14
Todd M Chapman, Christine R Baldus, Jon D Lurie, Steven D Glassman, Frank J Schwab, Christopher I Shaffrey, Virginie Lafage, Oheneba Boachie-Adjei, Han J Kim, Justin S Smith, Charles H Crawford, Lawrence G Lenke, Jacob M Buchowski, Charles Edwards, Tyler Koski, Stefan Parent, Stephen Lewis, Daniel G Kang, Jamal McClendon, Lionel Metz, Lukas P Zebala, Michael P Kelly, Kevin F Spratt, Keith H Bridwell
STUDY DESIGN: Prospective, cross-sectional study. OBJECTIVE: The aim of the study was to determine which radiographic parameters drive patient-reported outcomes (PROs) in primary presentation adult symptomatic lumbar scoliosis (ASLS). SUMMARY OF BACKGROUND DATA: Previous literature suggests correlations between PROs and sagittal plane deformity (sagittal vertical axis [SVA], pelvic incidence-lumbar lordosis [PI-LL] mismatch, pelvic tilt [PT])...
November 15, 2016: Spine
https://www.readbyqxmd.com/read/27750079/biomechanical-analysis-of-proximal-junctional-failure-following-adult-spinal-instrumentation-using-a-comprehensive-hybrid-modeling-approach
#15
Leo Fradet, Xiaoyu Wang, Lawrence G Lenke, Carl-Eric Aubin
BACKGROUND: Proximal junctional failure is a severe proximal junctional complication following adult spinal instrumentation and involving acute proximal junctional kyphotic deformity, mechanical failure at the upper instrumented vertebra or just above, and/or proximal junctional osseoligamentous disruption. Clinical studies have identified potential risk factors, but knowledge on their biomechanics is still lacking for addressing the proximal junctional failure issues. The objective of this study was to develop comprehensive computational modeling and simulation techniques to investigate proximal junctional failure...
November 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27743204/the-cranial-sagittal-vertical-axis-crsva-is-a-better-radiographic-measure-to-predict-clinical-outcomes-in-adult-spinal-deformity-surgery-than-the-c7-sva-a-monocentric-study
#16
Yong-Chan Kim, Lawrence G Lenke, Seon-Jong Lee, Jeffrey L Gum, Sirichai Wilartratsami, Kathy M Blanke
PURPOSE: Our study aimed to confirm the correlation between the Cranial Sagittal Vertical Axis (CrSVA) and patient-reported outcomes and to compare clinical correlation between CrSVA and C7 SVA in adult spinal deformity (ASD) patients. METHODS: 108 consecutive ASD patients were evaluated using the EOS(®) 2D/3D radio-imaging device. A vertical plumb line from the cranial center was utilized to measure the distance to the posterior corner of S1 (CrSVA-S), and to the centers of the hip (CrSVA-H), the knee (CrSVA-K), and ankle (CrSVA-A), as well as measuring the standard C7 SVA...
October 14, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27602410/utilization-trends-of-pedicle-subtraction-osteotomies-compared-to-posterior-spinal-fusion-for-deformity-a-national-database-analysis-between-2008-2011
#17
Jeffrey L Gum, Leah Y Carreon, Jacob M Buchowski, Lawrence G Lenke, Steven D Glassman
BACKGROUND: Increased awareness regarding the importance of the sagittal spinal profile has led to more aggressive correction of sagittal malalignment. The utilization trends of pedicle subtraction osteotomy (PSO) for sagittal plane correction in spinal deformity surgery have not been well characterized. METHODS: A commercially available database (PearlDiver, Inc) was queried for both Private Payor and 5 % Medicare claims from 2008 to 2011. Revision and clarification of the coding guidelines for PSO were introduced in 2008...
2016: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/27390914/predictors-of-distal-adding-on-in-thoracic-major-curves-with-ar-lumbar-modifiers
#18
Joshua S Murphy, Vidyadhar V Upasani, Burt Yaszay, Tracey P Bastrom, Carrie E Bartley, Amer Samdani, Lawrence G Lenke, Peter O Newton
STUDY DESIGN: Retrospective review of prospectively collected dataObjective: To determine whether the last substantially touched vertebra (LSTV) is a valid lowest instrumented vertebra (LIV) for both Lenke 1 and 2 curve patterns with AR lumbar modifiers,and to identify pre-operative risk factors of distal adding-on. SUMMARY OF BACKGROUND: Previous studies have recommended selecting the LSTV as the LIV for Lenke 1AR curves (main thoracic curve with 'A' lumbar modifier and L4 tilt to the right (thoracic overhang / King type IV curve)...
July 7, 2016: Spine
https://www.readbyqxmd.com/read/27151385/interpedicular-height-as-a-predictor-of-radicular-pain-in-adult-degenerative-scoliosis
#19
Ammar H Hawasli, Jodie Chang, Chester K Yarbrough, Karen Steger-May, Lawrence G Lenke, Ian G Dorward
BACKGROUND CONTEXT: Spine surgeons must correlate clinical presentation with radiographic findings in a patient-tailored approach. Despite the prevalence of adult degenerative scoliosis (ADS), there are few radiographic markers to predict the presence of radiculopathy. Emerging data suggest that spondylolisthesis, obliquity, foraminal stenosis, and curve concavity may be associated with radiculopathy in ADS. PURPOSE: The purpose of this study was to determine if radicular pain in ADS is associated with reduced interpedicular heights (IPHs) as measured on routine radiographs...
September 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27128389/results-of-revision-surgery-for-proximal-junctional-kyphosis-following-posterior-segmental-instrumentation-minimum-2-year-postrevision-follow-up
#20
Yong-Chan Kim, Lawrence G Lenke, Keith H Bridwell, Seung-Jae Hyun, Ki-Han You, Young-Woo Kim, Ho-Guen Chang, Michael P Kelly, Linda A Koester, Kathy M Blanke, David B Bumpass
STUDY DESIGN: A retrospective cohort study. OBJECTIVES: The aim of this study was to evaluate radiographic and patient-reported outcomes at minimum 2 years after revision surgery for proximal junctional kyphosis (PJK), correlating these results with PJK etiology. SUMMARY OF BACKGROUND DATA: There are no studies detailing the results of revision surgery for PJK following posterior segmental instrumentation. METHODS: Thirty-two consecutive patients treated with revision surgery after PJK above posterior fusions (25 women/7 men, average age at surgery 60...
December 15, 2016: Spine
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