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https://www.readbyqxmd.com/read/28937532/prevalence-risk-factors-and-characteristics-of-the-adding-on-phenomenon-in-idiopathic-scoliosis-after-correction-surgery-a-systematic-review-and-meta-analysis
#1
Mingyuan Yang, Yuechao Zhao, Xin Yin, Ziqiang Chen, Changwei Yang, Li Li, Ming Li
STUDY DESIGN: A systematic review and meta-analysis OBJECTIVE.: To discuss the prevalence, risk factors and characteristics of the 'adding-on' phenomenon in idiopathic scoliosis (IS). SUMMARY OF BACKGROUND DATA: There are controversies on the prevalence and risk factors of the 'adding-on' phenomenon. In addition, there is no comprehensive study to describe the characteristics of 'adding-on' in IS patients. METHODS: We performed a systematic online search using PubMed, EMBASE, Web of Science, the Cochrane Library and China WeiPu Library to identify eligible studies...
September 20, 2017: Spine
https://www.readbyqxmd.com/read/28930855/distal-adding-on-phenomenon-in-adolescent-idiopathic-scoliosis-patients-with-thoracolumbar-vertebra-fusion-a-case-control-study
#2
Wei Xu, Chao Chen, Yifan Li, Changwei Yang, Ming Li, Zhikun Li, Xiaodong Zhu
The adding-on phenomenon is a common complication in adolescent idiopathic scoliosis (AIS) patients after correction surgery. However, the risk factors of previous studies and the optimal treatment strategies remain controversial. The aim of this study was to identify new risk factors for the adding-on phenomenon after posterior correction surgery in AIS patients and compare different treatment strategies to guide the selection of the lowest instrumented vertebra (LIV).All types of Lenke AIS patients who received correction surgery at our center from January 2009 to July 2014 were analyzed...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28922278/defining-the-critical-elements-for-the-most-common-procedures-in-spine-surgery-a-consensus-of-orthopaedic-and-neurosurgical-surgeons
#3
Joseph L Laratta, Samuel Cohen-Tanugi, Jamal N Shillingford, Joseph M Lombardi, Lawrence G Lenke, K Daniel Riew, Ronald A Lehman, Steven C Ludwig
STUDY DESIGN: Survey. OBJECTIVE: To define the critical elements of common spine surgeries. SUMMARY OF BACKGROUND DATA: Despite significant relevance to the field of spine surgery, the term "critical element" of surgery has not been clearly defined. Every surgical procedure involves numerous steps, each with its own potential for complications and harm to the patient. Despite its crucial role in surgical training, billing, and the ethicality of concurrent surgery, the term "critical element" of surgery has not been defined...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28889983/analysing-the-change-of-sagittal-balance-in-patients-with-lenke-5-idiopathic-scoliosis
#4
Okan Ozkunt, Gökhan Karademir, Kerim Sariyilmaz, Halil Can Gemalmaz, Fatih Dikici, Unsal Domanic
OBJECTIVE: The aim of this study was to evaluate preoperative and postoperative spinopelvic parameters and the influence of lowest instrumented vertebrae on sagittal parameters in Lenke 5 Adolescent Idiopathic Scoliosis (AIS) patients. METHODS: A total of 42 patients (37 females, 5 males; mean age: 16.71 ± 3.46 years) were included in the study. Preoperative and postoperative last follow up lumbar lordosis (LL), thoracic kyphosis (TK), pelvic tilt (PT), pelvic incidence (PI) and sacral slope (SS) angles measured...
September 7, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28889339/incidence-and-risk-factors-for-postoperative-shoulder-imbalance-in-scoliosis-a-systematic-review-and-meta-analysis
#5
ShengFei Zhang, Liang Zhang, XinMin Feng, HuiLin Yang
PURPOSE: This is the first systematic review and meta-analysis to detect the incidence and risk factors for postoperative shoulder imbalance (PSI) in scoliosis. METHODS: A systematic online search was conducted to identify eligible studies. ES, OR and WMD with 95% CI were used to assess the incidence and risk factors associated with PSI. RESULTS: Twenty-six studies were recruited. The pooled incidence of PSI was 25% (95% CI 20-31%). The incidence in Lenke 1 AIS, Lenke 2 AIS, Lenke 5 AIS and mixed AIS was 20% (9-31%), 26% (15-37%), 31% (17-45%) and 27% (19-35%), respectively...
September 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28881527/-factors-correlated-with-height-gain-after-posterior-spinal-correction-surgery-in-lenke-1-adolescent-idiopathic-scoliosis
#6
B L Shi, L Xu, S H Mao, L L Xu, X Sun, Z Liu, J Qiao, Z Z Zhu, Y Qiu
Objective: To investigate the correlated factors of height gain (ΔSH) after posterior spinal correction surgery in Lenke 1 adolescent idiopathic scoliosis (AIS), and to propose the predictive model of ΔSH. Methods: From 2013 to 2015, a total of 150 Lenke 1 AIS patients undergoing posterior spinal correction surgery were included in the study, with the age of (14.3±2.9) years. The Cobb angle of major curve, thoracic kyphosis (TK) and lumbar lordosis (LL) were measured on both pre-op and post-op standing whole spine x-rays...
September 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28838992/the-role-of-constitutive-activation-of-fms-related-tyrosine-kinase-3-and-nras-kras-mutational-status-in-infants-with-kmt2a-rearranged-acute-lymphoblastic-leukemia
#7
Henning Fedders, Ameera Alsadeq, Juliane Schmäh, Fotini Vogiatzi, Martin Zimmermann, Anja Möricke, Lennart Lenk, Udo Zur Stadt, Martin A Horstmann, Rob Pieters, Martin Schrappe, Martin Stanulla, Gunnar Cario, Denis M Schewe
No abstract text is available yet for this article.
August 24, 2017: Haematologica
https://www.readbyqxmd.com/read/28836663/detection-of-herpesvirus-anguillae-anghv-1-in-european-eel-anguilla-anguilla-l-originating-from-northern-poland-assessment-of-suitability-of-selected-diagnostic-methods
#8
Tuan Thuc Nguyen, Yeonhwa Jin, Jolanta Kiełpińska, Sven M Bergmann, Matthias Lenk, Remigiusz Panicz
The Community Action Plan requests EU member states to implement measures that ensure the recovery of the severely depleted European eel stocks. One of the main threats is posed by Anguillid herpesvirus 1 (AngHV-1) leading to increased mortality in both wild and farmed eels. Following recommendations of the OIE to minimize the risk of obtaining false-negative results, the main aim of the study was to optimize diagnostic methods for AngHV-1 detection using conventional PCR, nested PCR and in situ hybridization assay...
August 24, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/28835232/full-fusion-of-proximal-thoracic-curve-helps-to-prevent-postoperative-cervical-tilt-in-lenke-type-2-adolescent-idiopathic-scoliosis-patients-with-right-elevated-shoulder
#9
Jun Jiang, Bang-Ping Qian, Yong Qiu, Bin Wang, Yang Yu, Ze-Zhang Zhu
BACKGROUND: To date, no study had reported the phenomenon of deteriorated postoperative cervical tilt in Lenke type 2 adolescent idiopathic scoliosis patients. The purpose of this study is to evaluate the cervical tilt in Lenke type 2 adolescent idiopathic scoliosis patients with right-elevated shoulder treated by either full fusion or partial/non fusion of the proximal thoracic curve. METHODS: A total of 30 Lenke type 2 AIS patients with preoperative right-elevated shoulder underwent posterior spinal instrumentation from 2009 to 2011 were included in this study...
August 23, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28828394/teriflunomide-slows-bvl-in-relapsing-ms-a-reanalysis-of-the-temso-mri-data-set-using-siena
#10
Ernst-Wilhelm Radue, Till Sprenger, Laura Gaetano, Nicole Mueller-Lenke, Steve Cavalier, Karthinathan Thangavelu, Michael A Panzara, Jessica E Donaldson, Fiona M Woodward, Jens Wuerfel, Jerry S Wolinsky, Ludwig Kappos
OBJECTIVE: To assess, using structural image evaluation using normalization of atrophy (SIENA), the effect of teriflunomide, a once-daily oral immunomodulator, on brain volume loss (BVL) in patients with relapsing forms of MS enrolled in the phase 3 TEMSO study. METHODS: TEMSO MR scans were analyzed (study personnel masked to treatment allocation) using SIENA to assess brain volume changes between baseline and years 1 and 2 in patients treated with placebo or teriflunomide...
September 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28827737/histological-evaluation-of-diabetic-neurodegeneration-in-the-retina-of-zucker-diabetic-fatty-zdf-rats
#11
Klaudia Szabó, Anna Énzsöly, Bulcsú Dékány, Arnold Szabó, Rozina I Hajdú, Tamás Radovits, Csaba Mátyás, Attila Oláh, Lenke K Laurik, Gábor M Somfai, Béla Merkely, Ágoston Szél, Ákos Lukáts
In diabetes, retinal dysfunctions exist prior to clinically detectable vasculopathy, however the pathology behind these functional deficits is still not fully established. Previously, our group published a detailed study on the retinal histopathology of type 1 diabetic (T1D) rat model, where specific alterations were detected. Although the majority of human diabetic patients have type 2 diabetes (T2D), similar studies on T2D models are practically absent. To fill this gap, we examined Zucker Diabetic Fatty (ZDF) rats - a model for T2D - by immunohistochemistry at the age of 32 weeks...
August 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28816826/tissue-engineered-bone-differentiated-from-human-adipose-derived-stem-cells-inhibit-posterolateral-fusion-in-an-athymic-rat-model
#12
Comron Saifi, Jonahtan Bernhard, Jamal N Shillingford, Petros Petridis, Samuel Robinson, X Edward Guo, Mark Weidenbaum, Ronald A Lehman, Howard S An, Lawrence G Lenke, Gordana Vunjak-Novakovic, Joseph L Laratta
STUDY DESIGN: Biological augmentation spinal arthrodesis trial in athymic rats OBJECTIVE.: To assess the efficacy of tissue-engineered bone to promote L4-L5 intertransverse process fusion in an athymic rat model. SUMMARY OF BACKGROUND DATA: Each year in the United States, over 400,000 spinal fusion surgeries are performed requiring bone graft. The current gold standard for posterolateral lumbar fusion is autogenous iliac crest bone graft (ICBG), but the harvesting of ICBG is associated with increased operative time and significant complications...
August 14, 2017: Spine
https://www.readbyqxmd.com/read/28816822/selecting-the-lstv-as-the-lower-instrumented-vertebra-in-the-treatment-of-lenke-types-1a-and-2a-adolescent-idiopathic-scoliosis-a-minimal-3-year-follow-up
#13
Jinyi Bai, Kai Chen, Qiang Wei, Ziqiang Chen, Yu Chen, Haijian Ni, Yingchuan Zhao, Ming Li
STUDY DESIGN: Retrospective study. OBJECTIVE: The purpose of this study was to verify the last substantially touched vertebra (LSTV) as the ideal lower instrumented vertebra (LIV) and to identify predictive factors of adding-on in patients with Lenke type 1A and 2A curve patterns when LSTV was chosed as the LIV. SUMMARY OF BACKGROUND DATA: Although several studies have indicated that the use of the LSTV as the LIV can obtain favorable outcomes in Lenke 1A and 2A curves, the factors identifying patients with Lenke 1A and 2A curve patterns who should undergo a fusion extending beyond the LSTV have not been identified...
August 14, 2017: Spine
https://www.readbyqxmd.com/read/28809795/pricing-of-staple-foods-at-supermarkets-versus-small-food-stores
#14
Caitlin E Caspi, Jennifer E Pelletier, Lisa J Harnack, Darin J Erickson, Kathleen Lenk, Melissa N Laska
Prices affect food purchase decisions, particularly in lower-income communities, where access to a range of food retailers (including supermarkets) is limited. The aim of this study was to examine differences in staple food pricing between small urban food stores and the closest supermarkets, as well as whether pricing differentials varied based on proximity between small stores and larger retailers. In 2014, prices were measured for 15 staple foods during store visits in 140 smaller stores (corner stores, gas-marts, dollar stores, and pharmacies) in Minneapolis/St...
August 15, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28780621/an-international-consensus-on-the-appropriate-evaluation-and-treatment-for-adults-with-spinal-deformity
#15
Sigurd H Berven, Steven J Kamper, Niccole M Germscheid, Benny Dahl, Christopher I Shaffrey, Lawrence G Lenke, Stephen J Lewis, Kenneth M Cheung, Ahmet Alanay, Manabu Ito, David W Polly, Yong Qiu, Marinus de Kleuver
PURPOSE: Evaluation and surgical management for adult spinal deformity (ASD) patients varies between health care providers. The purpose of this study is to identify appropriateness of specific approaches and management strategies for the treatment of ASD. METHODS: From January to July 2015, the AOSpine Knowledge Deformity Forum performed a modified Delphi survey where 53 experienced deformity surgeons from 24 countries, rated the appropriateness of management strategies for multiple ASD clinical scenarios...
August 5, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28776134/a-randomized-double-blinded-clinical-trial-to-evaluate-the-safety-and-efficacy-of-a-novel-superelastic-nickel-titanium-spinal-rod-in-adolescent-idiopathic-scoliosis-5-year-follow-up
#16
Jason Pui Yin Cheung, Dino Samartzis, Kelvin Yeung, Michael To, Keith Dip Kei Luk, Kenneth Man-Chee Cheung
PURPOSE: To evaluate the safety and efficacy of a superelastic shape-memory alloy (SNT) rod used in the treatment of adolescent idiopathic scoliosis (AIS). METHODS: AIS Patients with Lenke 1 curves undergoing fusion surgery were randomized (1:1) at the time of surgery to receive either the SNT or a conventional titanium alloy (CTA) rod. Radiographs were obtained preoperatively and postoperatively up to 5 years of follow-up. Parameters assessed included coronal and sagittal Cobb angles, and overall truncal and shoulder balance...
August 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28769939/evidence-for-active-uptake-and-deposition-of-si-based-defenses-in-tall-fescue
#17
Emma McLarnon, Simon McQueen-Mason, Ingo Lenk, Susan E Hartley
Silicon (Si) is taken up from the soil as monosilicic acid by plant roots, transported to leaves and deposited as phytoliths, amorphous silica (SiO2) bodies, which are a key component of anti-herbivore defense in grasses. Silicon transporters have been identified in many plant species, but the mechanisms underpinning Si transport remain poorly understood. Specifically, the extent to which Si uptake is a passive process, driven primarily by transpiration, or has both passive and active components remains disputed...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28768503/comparison-of-low-density-and-high-density-pedicle-screw-instrumentation-in-lenke-1-adolescent-idiopathic-scoliosis
#18
Mingkui Shen, Honghui Jiang, Ming Luo, Wengang Wang, Ning Li, Lulu Wang, Lei Xia
BACKGROUND: The correlation between implant density and deformity correction has not yet led to a precise conclusion in adolescent idiopathic scoliosis (AIS). The aim of this study was to evaluate the effects of low density (LD) and high density (HD) pedicle screw instrumentation in terms of the clinical, radiological and Scoliosis Research Society (SRS)-22 outcomes in Lenke 1 AIS. METHODS: We retrospectively reviewed 62 consecutive Lenke 1 AIS patients who underwent posterior spinal arthrodesis using all-pedicle screw instrumentation with a minimum follow-up of 24 months...
August 2, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28767626/a-detailed-comparative-analysis-of-anterior-versus-posterior-approach-to-lenke-5c-curves
#19
Firoz Miyanji, Luigi A Nasto, Tracey Bastrom, Amer F Samdani, Burt Yaszay, David Clements, Suken A Shah, Baron Lonner, Randal R Betz, Harry L Shufflebarger, Peter O Newton
STUDY DESIGN: Prospective cohort study OBJECTIVE.: To prospectively compare radiographic, perioperative and functional outcomes between anterior spinal instrumented fusion (ASIF) and posterior spinal instrumented fusion (PSIF) in Lenke 5C curves. SUMMARY OF BACKGROUND DATA: Historically, ASIF has been the treatment of choice for treatment of thoracolumbar adolescent idiopathic scoliosis (AIS). More recently, PSIF has gained popularity for its ease, versatility and amount of correction achieved...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28766159/what-is-the-difference-in-morphologic-features-of-the-thoracic-pedicle-between-patients-with-adolescent-idiopathic-scoliosis-and-healthy-subjects-a-ct-based-case-control-study
#20
Bo Gao, Wenjie Gao, Chong Chen, Qinghua Wang, Shaochun Lin, Caixia Xu, Dongsheng Huang, Peiqiang Su
BACKGROUND: Describing the morphologic features of the thoracic pedicle in patients with adolescent idiopathic scoliosis is necessary for placement of pedicle screws. Previous studies showed inadequate reliability owing to small sample size and heterogeneity of the patients surveyed. QUESTIONS/PURPOSES: To use CT scans (1) to describe the morphologic features of 2718 thoracic pedicles from 60 female patients with Lenke Type 1 adolescent idiopathic scoliosis and 60 age-, sex-, and height-matched controls; and (2) to classify the pedicles in three types based on pedicle width and analyze the distribution of each type...
August 1, 2017: Clinical Orthopaedics and related Research
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