keyword
MENU ▼
Read by QxMD icon Read
search

Lenke

keyword
https://www.readbyqxmd.com/read/28094795/impacts-of-chemical-gradients-on-microbial-community-structure
#1
Jianwei Chen, Anna Hanke, Halina E Tegetmeyer, Ines Kattelmann, Ritin Sharma, Emmo Hamann, Theresa Hargesheimer, Beate Kraft, Sabine Lenk, Jeanine S Geelhoed, Robert L Hettich, Marc Strous
Succession of redox processes is sometimes assumed to define a basic microbial community structure for ecosystems with oxygen gradients. In this paradigm, aerobic respiration, denitrification, fermentation and sulfate reduction proceed in a thermodynamically determined order, known as the 'redox tower'. Here, we investigated whether redox sorting of microbial processes explains microbial community structure at low-oxygen concentrations. We subjected a diverse microbial community sampled from a coastal marine sediment to 100 days of tidal cycling in a laboratory chemostat...
January 17, 2017: ISME Journal
https://www.readbyqxmd.com/read/28073838/gender-specific-relation-between-olfactory-sensitivity-and-disgust-perception
#2
Ilona Croy, Johanna Bendas, Nadja Wittrodt, Maria Lenk, Peter Joraschky, Kerstin Weidner
The perception of disgust is a powerful but yet puzzling emotion, aiming at the prevention of potential microbial pathogens and being directly linked to olfactory processing in its neurophysiological pathways via the anterior insular cortex. In sample of healthy participants with a natural variation in olfactory function, we investigated the relation between olfactory sensitivity and disgust perception. A total of 123 healthy individuals were surveyed with a disgust sensitivity questionnaire. Olfactory threshold was assessed in all participants using the Sniffin' Sticks...
January 10, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28065817/reproducibility-of-sagittal-radiographic-parameters-in-adolescent-idiopathic-scoliosis-a-guide-to-reference-values-using-serial-imaging
#3
Hwee Weng Dennis Hey, Gordon Chengyuan Wong, Chloe Chan Xiaoyun, Leok-Lim Lau, Naresh Kumar, Joseph Shantakumar Thambiah, John Nathaniel Ruiz, Ka-Po Gabriel Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Knowledge of sagittal radiographical parameters in AIS patients has not yet caught up with our understanding of their roles in patients with adult spinal deformity. It is likely that more emphasis will be placed in restoring sagittal parameters for AIS patients in the future. Therefore we need to understand how these parameters may vary in AIS to facilitate management plans. PURPOSE: To determine the reproducibility of sagittal spinal parameters on lateral film radiographs in patients with AIS...
January 5, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28060179/uniplanar-versus-fixed-pedicle-screws-in-the-correction-of-thoracic-kyphosis-in-the-treatment-of-adolescent-idiopathic-scoliosis-ais
#4
Siddharth A Badve, Ryan C Goodwin, David Gurd, Thomas Kuivila, Swamy Kurra, William F Lavelle
BACKGROUND: The aim of surgical treatment of scoliosis is to obtain fusion of the spinal column, balanced in the coronal and sagittal planes. Great success has been attained with coronal correction; however, the sagittal profile has received less attention, resulting in little correction of sagittal plane alignment. The purpose of this study was to compare uniplanar and fixed pedicle screws in the correction of the thoracic sagittal alignment in the treatment of adolescent idiopathic scoliosis (AIS)...
January 5, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28038696/predictors-for-postoperative-shoulder-balance-in-lenke-1-adolescent-idiopathic-scoliosis-a-prospective-cohort-study
#5
Alberto O Gotfryd, Maria Fernanda Silber Caffaro, Robert Meves, Osmar Avanzi
STUDY DESIGN: Prospective cohort. OBJECTIVES: To determine the predictors of the shoulder balance after main thoracic (MT) fusion in patients with Lenke 1 adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Imbalanced shoulders are a major cause of dissatisfaction in AIS patients. In Lenke 1 curves, MT curve fusion is supposed to lead to spontaneous correction of the proximal thoracic (PT) curve and thereby promote shoulder balance...
January 2017: Spine Deformity
https://www.readbyqxmd.com/read/28034352/development-of-a-novel-carbon-11-labeled-pet-radioligand-for-melanin-concentrating-hormone-receptor-1
#6
Hideyuki Igawa, Vladimir Stepanov, Lenke Tari, Shoki Okuda, Syunsuke Yamamoto, Shizuo Kasai, Yasutaka Nagisa, Jenny Häggkvist, Marie Svedberg, Miklós Tóth, Akihiro Takano, Christer Halldin
Melanin-concentrating hormone (MCH) is an attractive target for antiobesity agents and many drug discovery programs have been dedicated to identify small-molecule antagonists of melanin-concentrating hormone receptor 1 (MCHR1). The aim of this study was to develop a positron emission tomography (PET) tracer for MCHR1 for translation of preclinical pharmacology to clinic to enhance success rate of drug discovery programs. We identified 4-(cyclopropylmethoxy)-N-[8-methyl-3-({[(1-methyl-1H-pyrrol-2-yl)methyl]amino}ethyl)quinolin-7-yl]benzamide (Compound II) from Takeda MCHR1 antagonist library by utilizing binding affinity, log D value, physicochemical parameters ideal for a central nerve system agent, and synthetic feasibility of corresponding carbon-11 labeled radioligands as selection parameters for tracer candidates...
December 30, 2016: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/28025024/cervical-sagittal-alignment-in-adolescent-idiopathic-scoliosis-patients-lenke-type-1-6
#7
Lianlei Wang, Xinyu Liu
OBJECTIVE: We collected the radiographic and clinical data of 129 AIS patients (Lenke type 1-6) to analyze the characteristics of cervical sagittal alignment in adolescent idiopathic scoliosis patients and the correlations between cervical sagittal alignment and global sagittal alignment, and clinical symptoms. METHODS: 129 patients with AIS and 48 adolescent volunteers were included in this study. The angles of the main thoracic curve, proximal thoracic curve, thoracolumbar curve, lumbar curve, C2-7 Cobb angle, T5-12 Cobb angle, L1-5 Cobb angle, pelvic incidence, pelvic tilt, sacrum slop, C2-7 sagittal vertical axis, C7-S1 sagittal vertical axis, and T1 pelvic angle were included in radiographic measurements...
December 23, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28002917/simultaneous-double-rod-and-en-bloc-direct-vertebral-rotation-technique-for-correction-of-main-thoracic-adolescent-idiopathic-scoliosis-retrospective-analysis-of-14-cases
#8
C Faldini, F Perna, M Chehrassan, R Borghi, K Martikos, A Mazzotti, N Stefanini, L Cristofolini, F Traina
Adolescent idiopathic scoliosis (AIS) is a triplanar deformity associated with rib hump, especially when a principle thoracic curve is present. The aim of this study is to evaluate the results of AIS correction retrospectively, using simultaneous double rod derotation manoeuvre technique followed by en-bloc direct vertebral rotation (DVR). Fourteen patients were included in this study. Coronal and sagittal thoracic Cobb angle, global coronal balance, sagittal balance, rib hump prominence, Scoliosis Research Society outcome instrument score (SRS-22) and Walter Reed visual assessment scale (WR-VAS) values were recorded pre- and postoperatively and evaluated...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27999791/how-sublaminar-bands-affect-postoperative-sagittal-alignment-in-ais-patients-with-preoperative-hypokyphosis-results-of-a-series-of-34-patients-with-2-year-follow-up
#9
Sébastien Pesenti, Antoine Chalopin, Emilie Peltier, Elie Choufani, Matthieu Ollivier, Stéphane Fuentes, Benjamin Blondel, Jean-Luc Jouve
Hypokyphosis is currently observed in thoracic idiopathic scoliosis. The use of sublaminar bands allows a good restoration of sagittal balance of the spine. The aim of the study was to provide a middle-term radiographic analysis of patients with adolescent idiopathic scoliosis with preoperative hypokyphosis treated by posterior arthrodesis with sublaminar bands. This retrospective study included 34 patients with Lenke 1 scoliosis associated with hypokyphosis (TK < 20°). A radiographic evaluation was performed with a 2-year follow-up...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27941586/geometric-torsion-in-adolescent-idiopathic-scoliosis-a-surgical-outcomes-study-of-lenke-type-1-patients
#10
Jesse Shen, Samuel Kadoury, Hubert Labelle, Stefan Parent
STUDY DESIGN: Consecutive case series analysis. OBJECTIVE: To evaluate the surgical outcomes of patients with thoracic adolescent idiopathic scoliosis (AIS) in relation to different degrees of geometric torsion. SUMMARY OF BACKGROUND DATA: AIS is a three-dimensional (3D) deformity of the spine. A 3D classification of AIS, however, remains elusive because there is no widely accepted 3D parameter in the clinical practice. Recently, a new method of estimating geometric torsion has been proposed and detected two potential new 3D subgroups based on geometric torsion values...
December 15, 2016: Spine
https://www.readbyqxmd.com/read/27927572/the-spinopelvic-geometry-in-different-lenke-curve-types-of-adolescent-idiopathic-scoliosis
#11
M Farshad, S Catanzaro, S L Schmid
BACKGROUND: The Lenke classification is well established in differentiation of curve types in adolescent idiopathic scoliosis (AIS) and guides selection of fusion levels. However, to date, it has neglected the spinopelvic parameters that have been associated with compensatory mechanisms in balancing the human erect posture and adjacent segment problems after spinal fusion. The aim of this study was to investigate spinopelvic parameters in different types of AIS curves. MATERIAL AND METHODS: Preoperative whole-spine radiographs from 100 patients with AIS were reviewed and the curves were classified according to Lenke...
November 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927552/multicenter-comparison-of-3d-spinal-measurements-using-surface-topography-with-those-from-conventional-radiography
#12
Patrick Knott, Peter Sturm, Baron Lonner, Patrick Cahill, Marcel Betsch, Richard McCarthy, Michael Kelly, Lawrence Lenke, Randal Betz
INTRODUCTION: In pediatric spinal deformity the gold standard for curve surveillance remains standing full-column radiographs, but repeated exposure to ionizing radiation motivates us to look for nonradiographic solutions. This study tests a modern system of surface topography (ST) to determine whether it is reliable and reproducible. METHODS: Patients from 6 pediatric spinal deformity clinics were recruited for enrollment. Inclusion criteria were age 8-18; diagnosis of scoliosis measuring ≥10 and <50 degrees or increased kyphosis of ≥45 degrees...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927545/does-planned-staging-for-posterior-only-vertebral-column-resections-in-spinal-deformity-surgery-increase-perioperative-complications
#13
Jeffrey L Gum, Lawrence G Lenke, David Bumpass, Johnny Zhao, Patrick Sugrue, Isaac Karikari, Ra'Kerry Rahman, Leah Y Carreon
STUDY DESIGN: Propensity-matched case control. OBJECTIVES: To compare the perioperative complication rate between single- and two-stage posterior-only VCRs (2-pVCR). SUMMARY OF BACKGROUND DATA: A vertebral column resection (VCR) for severe spinal deformity is a technically challenging and lengthy procedure with a potentially high complication rate. Planned staging has an advantage of distributing operative time into 2 smaller, more manageable, intervals...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927544/assessment-of-lowest-instrumented-vertebra-tilt-on-radiographic-measurements-in-lenke-c-modifier-curves-undergoing-selective-thoracic-fusion-in-adolescent-idiopathic-scoliosis
#14
David L Skaggs, Derek A Seehausen, Kent T Yamaguchi, Raymond J Hah, Margaret L Wright, David B Bumpass, Han J Kim, Lindsay M Andras, Michael G Vitale, Lawrence G Lenke
STUDY DESIGN: Multicenter, retrospective cohort study. OBJECTIVES: The purpose of this study is to determine how the amount of residual lowest instrumented vertebra (LIV) tilt correlates with radiographic measurements. SUMMARY OF BACKGROUND DATA: When performing a selective thoracic posterior spinal fusion for adolescent idiopathic scoliosis (AIS), the LIV may be tilted into the lumbar curve or made horizontal. METHODS: This is a multicenter retrospective study of 33 consecutive patients with AIS, Lenke types 1 to 4, lumbar modifier C, and a minimum follow-up of 2 years, who underwent selective thoracic posterior spinal fusions...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927501/morphometric-analysis-of-the-thoracic-intervertebral-foramen-osseous-anatomy-in-adolescent-idiopathic-scoliosis-using-low-dose-computed-tomography
#15
Thorbjorn J Loch-Wilkinson, Maree T Izatt, Robert D Labrom, Geoffrey N Askin, Mark J Pearcy, Clayton J Adam
PURPOSE: The dimensions of the thoracic intervertebral foramen in adolescent idiopathic scoliosis (AIS) have not previously been quantified. Better understanding of the dimensions of the foramen may be useful in surgical planning. This study describes a reproducible method for measurement of the thoracic foramen in AIS using computed tomography (CT). METHODS: In 23 preoperative female patients with Lenke 1 type AIS with right-side convexity major curves confined to the thoracic spine the foraminal height (FH), foraminal width (FW), pedicle to superior articular process distance (P-SAP), and cross-sectional foraminal area (FA) were measured using multiplanar reconstructed CT...
May 2016: Spine Deformity
https://www.readbyqxmd.com/read/27906378/cool-white-light-emitting-three-stack-oled-structures-for-amoled-display-applications
#16
Ramon Springer, Byoung Yeop Kang, Raju Lampande, Dae Hyun Ahn, Simone Lenk, Sebastian Reineke, Jang Hyuk Kwon
This paper demonstrates 2-stack and 3-stack white organic light-emitting diodes (WOLEDs) with fluorescent blue and phosphorescent yellow emissive units. The 2-stack and 3-stack WOLED comprises blue-yellow and blue-blue-yellow (blue-yellow-blue) combinations. The position of the yellow emitter and possible cavity lengths in different stack architectures are theoretically and experimentally investigated to reach Commission Internationale de L'Eclairage (CIE) coordinates of near (0.333/0.333). Here, a maximum external quantum efficiency (EQE) of 23...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27902790/accuracy-of-genomic-prediction-in-a-commercial-perennial-ryegrass-breeding-program
#17
Dario Fè, Bilal H Ashraf, Morten G Pedersen, Luc Janss, Stephen Byrne, Niels Roulund, Ingo Lenk, Thomas Didion, Torben Asp, Christian S Jensen, Just Jensen
The implementation of genomic selection (GS) in plant breeding, so far, has been mainly evaluated in crops farmed as homogeneous varieties, and the results have been generally positive. Fewer results are available for species, such as forage grasses, that are grown as heterogenous families (developed from multiparent crosses) in which the control of the genetic variation is far more complex. Here we test the potential for implementing GS in the breeding of perennial ryegrass ( L.) using empirical data from a commercial forage breeding program...
November 2016: Plant Genome
https://www.readbyqxmd.com/read/27900714/is-there-asymmetry-between-the-concave-and-convex-pedicles-in-adolescent-idiopathic-scoliosis-a-ct-investigation
#18
Colin M Davis, Caroline A Grant, Mark J Pearcy, Geoffrey N Askin, Robert D Labrom, Maree T Izatt, Clayton J Adam, J Paige Little
BACKGROUND: Adolescent idiopathic scoliosis is a complex three-dimensional deformity of the spine characterized by deformities in the sagittal, coronal, and axial planes. Spinal fusion using pedicle screw instrumentation is a widely used method for surgical correction in severe (coronal deformity, Cobb angle > 45°) adolescent idiopathic scoliosis curves. Understanding the anatomic difference in the pedicles of patients with adolescent idiopathic scoliosis is essential to reduce the risk of neurovascular or visceral injury through pedicle screw misplacement...
November 29, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27888080/comparison-of-consecutive-interval-and-skipped-pedicle-screw-techniques-in-moderate-lenke-type-1-adolescent-idiopathic-scoliosis
#19
Ming Luo, Mingkui Shen, Wengang Wang, Lei Xia
OBJECTIVE: To compare perioperative, radiographic and Scoliosis Research Society (SRS)-22 outcomes of consecutive, interval, and skipped pedicle screw techniques in patients with moderate Lenke type 1 adolescent idiopathic scoliosis (AIS). METHODS: We retrospectively reviewed 65 consecutive moderate Lenke type 1 AIS patients at a single institution, using all-pedicle screw constructs with a minimum of 2-years follow-up. In the consecutive group (C group, n=22), pedicle screws were instrumented at consecutive levels bilaterally...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27867080/biomechanical-advantages-of-robot-assisted-pedicle-screw-fixation-in-posterior-lumbar-interbody-fusion-compared-with-freehand-technique-in-a-prospective-randomized-controlled-trial-perspective-for-patient-specific-finite-element-analysis
#20
Ho-Joong Kim, Kyoung-Tak Kang, Sung-Cheol Park, Oh-Hyo Kwon, Juhyun Son, Bong-Soon Chang, Choon-Ki Lee, Jin S Yeom, Lawrence G Lenke
BACKGROUND CONTEXT: There have been conflicting results on the surgical outcome of lumbar fusion surgery using two different techniques: robot-assisted pedicle screw fixation and conventional freehand technique. In addition, there have been no studies about the biomechanical issues between both techniques. PURPOSE: This study aimed to investigate the biomechanical properties in terms of stress at adjacent segments using robot-assisted pedicle screw insertion technique (robot-assisted, minimally invasive posterior lumbar interbody fusion, Rom-PLIF) and freehand technique (conventional, freehand, open approach, posterior lumbar interbody fusion, Cop-PLIF) for instrumented lumbar fusion surgery...
November 17, 2016: Spine Journal: Official Journal of the North American Spine Society
keyword
keyword
31103
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"