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https://www.readbyqxmd.com/read/28642669/concordance-for-curve-type-in-idiopathic-scoliosis-among-family-members
#1
Clarissa Miranda Carneiro de Albuquerque Olbertz, Jérôme Sales de Gauzy, Paulo Cezar Vidal Carneiro de Albuquerque, Frank Accadbled, Paula Eduarda Miranda Carneiro de Albuquerque, José Lamartine de Andrade Aguiar
OBJECTIVE: To evaluate the concordance for the curve pattern, side and levels of the superior apical vertebrae, apex and inferior apical vertebrae of curves in patients and their relatives with idiopathic scoliosis. METHODS: Concordance according to the Lenke classification for curve pattern, side and levels of the superior apical vertebrae, apex and inferior apical vertebrae were evaluated comparative and prospectively in 243 pairs of patients and respective relatives with idiopathic scoliosis...
May 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28620291/network-wide-adaptive-burst-detection-depicts-neuronal-activity-with-improved-accuracy
#2
Inkeri A Välkki, Kerstin Lenk, Jarno E Mikkonen, Fikret E Kapucu, Jari A K Hyttinen
Neuronal networks are often characterized by their spiking and bursting statistics. Previously, we introduced an adaptive burst analysis method which enhances the analysis power for neuronal networks with highly varying firing dynamics. The adaptation is based on single channels analyzing each element of a network separately. Such kind of analysis was adequate for the assessment of local behavior, where the analysis focuses on the neuronal activity in the vicinity of a single electrode. However, the assessment of the whole network may be hampered, if parts of the network are analyzed using different rules...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28616707/customer-characteristics-and-shopping-patterns-associated-with-healthy-and-unhealthy-purchases-at-small-and-non-traditional-food-stores
#3
Kathleen M Lenk, Caitlin E Caspi, Lisa Harnack, Melissa N Laska
Small and non-traditional food stores (e.g., corner stores) are often the most accessible source of food for residents of lower income urban neighborhoods in the U.S. Although healthy options are often limited at these stores, little is known about customers who purchase healthy, versus less healthy, foods/beverages in these venues. We conducted 661 customer intercept interviews at 105 stores (corner stores, gas marts, pharmacies, dollar stores) in Minneapolis/St. Paul, Minnesota, assessing all food and beverage items purchased...
June 14, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28604992/a-new-bioinspired-collagen-hydroxyapatite-bone-graft-substitute-in-adult-scoliosis-surgery-results-at-3-year-follow-up
#4
Pietro Giorgi, Dario Capitani, Simone Sprio, Monica Sandri, Anna Tampieri, Valentina Canella, Angelo Nataloni, Giuseppe R Schirò
BACKGROUND: Spinal fusion is a common procedure used for surgical treatment of spinal deformity. In recent years, many bone graft substitutes (BGS) have been developed to provide good arthrodesis when the available autologous bone harvested from the patient is not enough. The aim of this study was to analyze the use of a new-generation composite material (RegenOss) made of Mg-hydroxyapatite nanoparticles nucleated on type I collagen to obtain long posterolateral fusion in adult scoliosis surgery...
June 7, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28604495/when-do-patients-return-to-physical-activities-and-athletics-after-scoliosis-surgery-a-validated-patient-questionnaire-based-study
#5
Vishal Sarwahi, Stephen Wendolowski, Rachel Gecelter, Kathleen Maguire, Melanie Gambassi, Dana Orlando, Yungtai Lo, Terry Amaral
STUDY DESIGN: A retrospective chart review with a survey OBJECTIVES.: This study seeks to determine time of return to normal, physical and athletic activities and delaying factors after all pedicle screw fixation. SUMMARY OF BACKGROUND DATA: Return to athletic activity after PSF in AIS is largely dependent on surgeon's philosophy. Some allow contact and collision sports by 6 and 12 months, while others avoid contact sports for 1 year and never allow collision sports...
June 9, 2017: Spine
https://www.readbyqxmd.com/read/28601991/the-mechanisms-underlying-the-variety-of-preoperative-directionalities-of-shoulder-tilting-in-adolescent-idiopathic-scoliosis-patients-with-double-thoracic-curve
#6
Jun Jiang, Bang-Ping Qian, Yong Qiu, Bin Wang, Yang Yu, Ze-Zhang Zhu
PURPOSE: Preoperative directionality of shoulder tilting seems to be independent of the radiographic features of proximal thoracic (PT) curve in adolescent idiopathic scoliosis (AIS) patients. To date, no study had investigated the mechanisms underlying the variety of preoperative directionalities of shoulder tilting in AIS patients. The purpose of this study was to evaluate the differences of radiographic features between Lenke type 2 (double thoracic curve) AIS patients with different preoperative directionalities of shoulder tilting...
June 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28601989/selective-thoracic-fusion-of-a-left-decompensated-main-thoracic-curve-proceed-with-caution
#7
T Barrett Sullivan, Tracey P Bastrom, Carrie E Bartley, Suken A Shah, Baron S Lonner, Jahangir Asghar, Firoz Miyanji, Peter O Newton, Burt Yaszay
PURPOSE: Previous research has shown that with certain idiopathic scoliosis curve types, performing a selective thoracic fusion (STF) is associated with an increased risk of coronal decompensation post-operatively. The purpose of the current study was to determine the influence of curve correction and fusion level on post-operative balance in STF for adolescent idiopathic scoliosis patients with pre-operative coronal decompensation. METHODS: A multicenter database was queried for subjects with right Lenke 1-4C curves, pre-operative left coronal imbalance, and 2-year follow-up who underwent STF (caudal fusion level of L1 or proximal)...
June 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28590377/brace-success-is-related-to-curve-type-in-patients-with-adolescent-idiopathic-scoliosis
#8
Rachel M Thompson, Elizabeth W Hubbard, Chan-Hee Jo, Donald Virostek, Lori A Karol
BACKGROUND: Curve magnitude and skeletal maturity are important factors in determining the efficacy of bracing for the treatment of adolescent idiopathic scoliosis, but curve morphology may also affect brace success. The purpose of this study was to determine the influence of curve morphology on the response to bracing with a thoracolumbosacral orthosis (TLSO). METHODS: A retrospective review of patients managed with an orthosis for the treatment of adolescent idiopathic scoliosis who were prospectively enrolled at the initiation of brace wear and followed through completion of bracing or surgery was performed...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28589303/three-types-of-sagittal-alignment-regarding-compensation-in-asymptomatic-adults-the-contribution-of-the-spine-and-lower-limbs
#9
Hongda Bao, Renaud Lafage, Barthelemy Liabaud, Jonathan Elysée, Bassel G Diebo, Gregory Poorman, Cyrus Jalai, Peter Passias, Aaron Buckland, Shay Bess, Thomas Errico, Lawrence G Lenke, Munish Gupta, Han Jo Kim, Frank Schwab, Virginie Lafage
PURPOSE: A comprehensive understanding of normative sagittal profile is necessary for adult spinal deformity. Roussouly described four sagittal alignment types based on sacral slope, lumbar lordosis, and location of lumbar apex. However, the lower limb, a newly described component of spinal malalignment compensation, is missing from this classification. This study aims to propose a full-body sagittal profile classification in an asymptomatic population based on full-body imaging. METHODS: This is a retrospective analysis of a prospective single-center study of 116 asymptomatic volunteers...
June 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28586498/increased-hair-cortisol-concentrations-in-patients-with-progressive-keratoconus
#10
Janine Lenk, Eberhard Spoerl, Tobias Stalder, Susann Schmiedgen, Robert Herber, Lutz E Pillunat, Frederik Raiskup
PURPOSE: To investigate hair cortisol concentration (HCC), a biochemical correlate of chronic psychological stress, and its relationship to the progression of keratoconus. METHODS: Eighty-six participants were included in this prospective observational study (32 patients with progressive keratoconus, 32 patients with stable keratoconus, and 22 healthy controls). Hair cortisol concentrations were determined from 3-cm hair strands collected near the scalp from patients and controls as an index of cumulative cortisol secretion during the 3-month period prior to hair sampling...
June 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28583477/measures-of-spike-train-synchrony-for-data-with-multiple-time-scales
#11
Eero Satuvuori, Mario Mulansky, Nebojsa Bozanic, Irene Malvestio, Fleur Zeldenrust, Kerstin Lenk, Thomas Kreuz
BACKGROUND: Measures of spike train synchrony are widely used in both experimental and computational neuroscience. Time-scale independent and parameter-free measures, such as the ISI-distance, the SPIKE-distance and SPIKE-synchronization, are preferable to time scale parametric measures, since by adapting to the local firing rate they take into account all the time scales of a given dataset. NEW METHOD: In data containing multiple time scales (e.g. regular spiking and bursts) one is typically less interested in the smallest time scales and a more adaptive approach is needed...
June 3, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28583131/association-between-store-food-environment-and-customer-purchases-in-small-grocery-stores-gas-marts-pharmacies-and-dollar-stores
#12
Caitlin E Caspi, Kathleen Lenk, Jennifer E Pelletier, Timothy L Barnes, Lisa Harnack, Darin J Erickson, Melissa N Laska
BACKGROUND: Purchases at small/non-traditional food stores tend to have poor nutritional quality, and have been associated with poor health outcomes, including increased obesity risk The purpose of this study was to examine whether customers who shop at small/non-traditional food stores with more health promoting features make healthier purchases. METHODS: In a cross-sectional design, data collectors assessed store features in a sample of 99 small and non-traditional food stores not participating in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) in Minneapolis/St...
June 5, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28576837/hypothalamic-inflammation-in-human-obesity-is-mediated-by-environmental-and-genetic-factors
#13
Carina Kreutzer, Sönke Peters, Dominik M Schulte, Daniela Fangmann, Kathrin Türk, Stephan Wolff, Thilo van Eimeren, Markus Ahrens, Jan Beckmann, Clemens Schafmayer, Thomas Becker, Tina Kerby, Axel Rohr, Christian Riedel, Femke-Anouska Heinsen, Frauke Degenhardt, Andre Franke, Philip Rosenstiel, Nana Zubek, Christian Henning, Sandra Freitag-Wolf, Astrid Dempfle, Aristea Psilopanagioti, Helen Petrou-Papadaki, Lennart Lenk, Olav Jansen, Stefan Schreiber, Matthias Laudes
Obesity is associated with hypothalamic inflammation (HI) in animal models. In the present study we examined the mediobasal hypothalamus (MBH) of 57 obese human subjects and 54 age- and sex- matched non-obese controls by MRI and analyzed the T2-hyperintensity as a measure of HI. Obese subjects exhibited T2-hyperintensity in the left but not the right MBH which was strongly associated with systemic low-grade inflammation. MRI-spectroscopy revealed the number of neurons in the left hypothalamic region to be similar in obese versus control subjects suggesting functional but not structural impairment due to the inflammatory process...
June 2, 2017: Diabetes
https://www.readbyqxmd.com/read/28570316/severity-of-inhalation-injury-is-predictive-of-alterations-in-gas-exchange-and-worsened-clinical-outcomes
#14
Tia Sutton, Ian Lenk, Peggie Conrad, Marcia Halerz, Michael Mosier
Inhalation injury (INH) is present in one third of large burn injuries and increases oxygenation and fluid resuscitation requirements, incidences of pulmonary complications, risk for multiple organ dysfunction syndrome (MODS), and overall mortality. Previous studies have demonstrated inconsistent correlation between bronchoscopic evaluation and clinical outcomes. The authors reviewed 161 patients admitted with a diagnosis of INH or underwent diagnostic bronchoscopy for suspected INH over a period of 8.5 years...
May 12, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28554809/five-year-outcomes-of-the-first-distal-uninstrumented-vertebra-after-posterior-fusion-for-adolescent-idiopathic-scoliosis-lenke-1-or-2
#15
J-L Clément, F Solla, C Morin, W Lakhal, J Sales de Gauzy, J Leroux, J-M Gennari, F H Parent, G Kreichati, S Wolf, I Obeid, A Tran
BACKGROUND: Tilt of the first distal uninstrumented vertebra (FDUV) reflects changes in the main curve and compensatory lumbar curve after posterior fusion to treat thoracic adolescent idiopathic scoliosis (AIS). HYPOTHESIS: FDUV tilt 5 years or more post-fusiondepends chiefly on reduction of the maincurve and on other factors such as selection of the last instrumented vertebra. MATERIAL AND METHOD: A multicentre retrospective cohort of 182 patients with Lenke 1 or 2 AIStreated with posterior instrumentation and followed up for a mean of 8 years and a minimum of 5 years was studied...
May 26, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28547576/thoraco-lumbar-selective-fusion-in-adolescent-idiopathic-scoliosis-with-lenke-c-modifier-curves-clinical-and-radiographic-analysis-at-10-year-follow-up
#16
Laura Scaramuzzo, Fabrizio Giudici, Daniele Bongetta, Eleonora Caboni, Leone Minoia, Antonino Zagra
PURPOSE: To examine the radiological and clinical outcomes of a single-center case series of selective thoracic fusions (STF) in adolescent idiopathic scoliosis with Lenke C modifier curves, with a long-term follow-up. METHODS: We evaluated at 6 months and 10 years different radiological parameters on both thoracic and lumbar districts: coronal curves, sagittal curves, apical vertebral translation (AVT), and apical vertebral rotation (AVR). The clinical outcome was determined using the SRS 22 score...
May 25, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28545443/cervical-kyphosis-in-patients-with-lenke-type-1-adolescent-idiopathic-scoliosis-the-prediction-of-thoracic-inlet-angle
#17
Ce Zhu, Xi Yang, Bangjian Zhou, Lei Wang, Chunguang Zhou, Tingxian Ling, Limin Liu, Yueming Song
BACKGROUND: Several studies have explored cervical kyphosis (CK) in adolescent idiopathic scoliosis (AIS) patients. However, few studies have evaluated the cervical alignment in these patients according to their coronal curve type. The aim of this study was to analyze the radiological features of cervical sagittal alignment in Lenke 1 AIS patients before and after surgery. METHODS: This is a retrospective study enrolled 50 patients. Preoperative and postoperative standing full-length radiographs (at last follow-up after operation) were used to measure the coronal and sagittal parameters...
May 25, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28536946/determinants-of-the-biomechanical-and-radiological-outcome-of-surgical-correction-of-adolescent-idiopathic-scoliosis-surgery-the-role-of-rod-properties-and-patient-characteristics
#18
Fabrizio Giudici, Fabio Galbusera, Antonino Zagra, Hans-Joachim Wilke, Marino Archetti, Laura Scaramuzzo
PURPOSE: Aim of the study was to evaluate the role of the mechanical properties of the rod and of the characteristics of the patients (age, skeletal maturity, BMI, and Lenke type) in determining the deformity correction, its maintenance over time and the risk of mechanical failure of the instrumentation. METHODS: From March 2011 to December 2014 120 patients affected by AIS underwent posterior instrumented fusion. Two 5.5-mm CoCr rods were implanted in all patients...
May 23, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28516166/onset-and-remodeling-of-coronal-imbalance-after-selective-posterior-thoracic-fusion-for-lenke-1c-and-2c-adolescent-idiopathic-scoliosis-a-pilot-study
#19
Masayuki Ishikawa, Kai Cao, Long Pang, Nobuyuki Fujita, Mitsuru Yagi, Naobumi Hosogane, Takashi Tsuji, Masafumi Machida, Shinichi Ishihara, Makoto Nishiyama, Yasuyuki Fukui, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
BACKGROUND: Postoperative coronal imbalance is a significant problem after selective thoracic fusion for primary thoracic and compensatory lumbar curves in adolescent idiopathic scoliosis (AIS). However, longitudinal studies on postoperative behavior of coronal balance are lacking. This multicenter retrospective study was conducted to analyze factors related to onset and remodeling of postoperative coronal imbalance after posterior thoracic fusion for Lenke 1C and 2C AIS. METHODS: Twenty-one Lenke 1C or 2C AIS patients, who underwent posterior thoracic fusion ending at L3 or above, were included with a minimum 2-year follow-up...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28475019/retrospective-analysis-underestimates-neurological-deficits-in-complex-spinal-deformity-surgery-a-scoli-risk-1-study
#20
Michael P Kelly, Lawrence G Lenke, Jakub Godzik, Ferran Pellise, Christopher I Shaffrey, Justin S Smith, Stephen J Lewis, Christopher P Ames, Leah Y Carreon, Michael G Fehlings, Frank Schwab, Adam L Shimer
OBJECTIVE The authors conducted a study to compare neurological deficit rates associated with complex adult spinal deformity (ASD) surgery when recorded in retrospective and prospective studies. Retrospective studies may underreport neurological deficits due to selection, detection, and recall biases. Prospective studies are expensive and more difficult to perform, but they likely provide more accurate estimates of new neurological deficit rates. METHODS New neurological deficits were recorded in a prospective study of complex ASD surgeries (pSR1) with a defined outcomes measure (decrement in American Spinal Injury Association lower-extremity motor score) for neurological deficits...
May 5, 2017: Journal of Neurosurgery. Spine
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