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https://www.readbyqxmd.com/read/28212519/early-calibration-of-the-hpa-axis-by-maternal-psychopathology
#1
Heidemarie Laurent
Given the central role of stress-responsive neurophysiology in mental and physical health, it is important to understand how particular patterns of stress responsivity may become entrained by the early caregiving environment. In this study we investigated links between maternal depression and anxiety symptom profiles and within-infant development of hypothalamic-pituitary-adrenal (HPA) axis responses from 6 to 18 months of life. Associations with infant cognitive and social-emotional development were also tested to gauge the adjustment implications of HPA response trajectories...
February 1, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28212108/the-association-between-pre-pregnancy-obesity-and-screening-results-of-depression-for-all-trimesters-of-pregnancy-postpartum-and-1-year-after-birth-a-cohort-study
#2
Hanieh Salehi-Pourmehr, Sakineh Mohammad-Alizadeh, Nayyer Jafarilar-Agdam, Somayyeh Rafiee, Azizeh Farshbaf-Khalili
OBJECTIVE: To determine the relationship between pre-pregnancy obesity and screening results of gestational and post-delivery depression in women referred to the health centers of Tabriz, Iran. METHODS: In this cohort study, 62 and 245 pregnant women with class 2-3 obesity [body mass index (BMI)≥35 kg/m2] and normal-weight (BMI 18.5-24.9 kg/m2) were enrolled, respectively, in the first trimester of pregnancy from December 2012 to January 2016. For matching of groups, nulliparous and multiparous mothers aged 18-35 years were selected with the ratio of 1:4 in obese and normal BMI groups from the same recruitment center and to controlling the confounder factors, inclusion criteria were considered...
February 17, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28199455/paternal-depression-symptoms-during-pregnancy-and-after-childbirth-among-participants-in-the-growing-up-in-new-zealand-study
#3
Lisa Underwood, Karen E Waldie, Elizabeth Peterson, Stephanie D'Souza, Marjolein Verbiest, Frances McDaid, Susan Morton
Importance: Antenatal and postnatal depression are known to be common and associated with poor outcomes for women and their children. There is little evidence on depression symptoms among men during the perinatal period. Objective: To identify characteristics associated with depression symptoms among men whose partners were pregnant and subsequently gave birth. Design, Setting, and Participants: A longitudinal cohort study provided data from a demographically diverse sample of 3523 New Zealand men who completed interviews during their partner's pregnancy and 9 months after the birth of their child...
February 15, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28198084/single-dose-intravenous-iron-infusion-or-oral-iron-for-treatment-of-fatigue-after-postpartum-haemorrhage-a%C3%A2-randomized-controlled-trial
#4
C Holm, L L Thomsen, A Norgaard, J Langhoff-Roos
BACKGROUND AND OBJECTIVES: To evaluate the clinical efficacy of a single-dose intravenous infusion of iron isomaltoside compared with current treatment practice with oral iron measured by physical fatigue in women after postpartum haemorrhage. MATERIALS AND METHODS: Single-centre, open-label, randomized controlled trial. Participants received intravenous iron (n = 97) or oral iron (n = 99), and completed the Multidimensional Fatigue Inventory and Edinburgh Postnatal Depression Scale, and haematological and iron parameters were measured...
February 15, 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/28197749/the-effect-of-life-style-based-education-on-the-fathers-anxiety-and-depression-during-pregnancy-and-postpartum-periods-a-randomized-controlled-trial
#5
Sakineh Mohammad-Alizadeh Charandabi, Mojgan Mirghafourvand, Fovzieh Sanaati
Due to the harmful effects of prenatal and postnatal anxiety and depression on fathers, the aim of this study was to determine the impact of lifestyle-based training on paternal depression and anxiety (primary outcomes) during the prenatal and postnatal periods. This single-blind randomized controlled clinical trial was conducted on 126 spouses of pregnant women with gestational ages of 24-28 weeks. They were followed up until 6 weeks after childbirth. Using the block randomization method and stratified based on the number of children, the eligible samples were divided into two groups (one receiving two weekly group lifestyle-based training session (lasting 60-90 min) and a control group)...
February 14, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28192175/increased-anxiety-like-phenotype-in-female-guinea-pigs-following-reduced-neurosteroid-exposure-in-utero
#6
Angela L Cumberland, Hannah K Palliser, Gabrielle K Crombie, David W Walker, Jonathan J Hirst
Neurosteroids are essential for aiding proper fetal neurodevelopment. Pregnancy compromises such as preterm birth, prenatal stress and intrauterine growth restriction are associated with an increased risk of developing behavioural and mood disorders, particularly during adolescence. These pathologies involve the premature loss or alteration of trophic steroid hormones reaching the fetus leading to impaired neurodevelopment. While the specific programming mechanisms are yet to be fully elucidated, in adult life, dysfunctions of allopregnanolone action are prevalent in individuals with depression, post-traumatic stress disorder and anxiety disorders...
February 9, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28191626/intermittent-auscultation-ia-of-fetal-heart-rate-in-labour-for-fetal-well-being
#7
REVIEW
Ruth Martis, Ova Emilia, Detty S Nurdiati, Julie Brown
BACKGROUND: The goal of fetal monitoring in labour is the early detection of a hypoxic baby. There are a variety of tools and methods available for intermittent auscultation (IA) of the fetal heart rate (FHR). Low- and middle-income countries usually have only access to a Pinard/Laënnec or the use of a hand-held Doppler device. Currently, there is no robust evidence to guide clinical practice on the most effective IA tool to use, timing intervals and length of listening to the fetal heart for women during established labour...
February 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28188834/amelioration-of-cerebellar-dysfunction-in-rats-following-postnatal-ethanol-exposure-using-low-intensity-pulsed-ultrasound
#8
Hiva Mohammadi Bolbanabad, Enayat Anvari, Mohammad Jafar Rezai, Ardashir Moayeri, Mohammad Reza Kaffashian
BACKGROUND: The neonatal development stage of the cerebellum in rats is equivalent to a human foetus in the third trimester of pregnancy. In this stage, cell proliferation, migration, differentiation, and synaptogenesis occur. Clinical and experimental findings have shown that ethanol exposure during brain development causes a variety of disruptions to the brain, including neurogenesis depression, delayed neuronal migration, changes in neurotransmitter synthesis, and neuronal depletion...
February 7, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28188472/the-effect-of-postpartum-depression-and-current-mental-health-problems-of-the-mother-on-child-behaviour-at-eight-years
#9
R Closa-Monasterolo, M Gispert-Llaurado, J Canals, V Luque, M Zaragoza-Jordana, B Koletzko, V Grote, M Weber, D Gruszfeld, K Szott, E Verduci, A ReDionigi, J Hoyos, G Brasselle, J Escribano Subías
Background Maternal postpartum depression (PPD) could affect children's emotional development, increasing later risk of child psychological problems. The aim of our study was to assess the association between child's emotional and behavioural problems and mother's PPD, considering maternal current mental health problems (CMP). Methods This is a secondary analysis from the EU-Childhood Obesity Project (NCT00338689). Women completed the Edinburgh Postnatal Depression Scale (EPDS) at, 2, 3 and 6 months after delivery and the General Health Questionnaire (GHQ-12) to assess CMP once the children reached the age of 8 years...
February 11, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28182105/neuroplastic-correlates-in-the-mpfc-underlying-the-impairment-of-stress-coping-ability-and-cognitive-flexibility-in-adult-rats-exposed-to-chronic-mild-stress-during-adolescence
#10
Yu Zhang, Feng Shao, Qiong Wang, Xi Xie, Weiwen Wang
Using a valid chronic mild stress (CMS) model of depression, we found that adolescent (postnatal days [PND] 28-41) CMS induced transient alterations in anhedonia that did not persist into adulthood after a 3-week recovery period. Previously stressed adult rats exhibited more immobility/despair behaviors in the forced swimming test and a greater number of trials to reach criterion in the set-shifting task, suggesting the impaired ability to cope with stressors and the cognitive flexibility that allows adaptation to dynamic environments during adulthood...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28176274/microglial-function-during-glucose-deprivation-inflammatory-and-neuropsychiatric-implications
#11
Matthew A Churchward, Devan R Tchir, Kathryn G Todd
Inflammation is increasingly recognized as a contributor to the pathophysiology of neuropsychiatric disorders, including depression, anxiety disorders and autism, though the factors leading to contextually inappropriate or sustained inflammation in pathological conditions are yet to be elucidated. Microglia, as the key mediators of inflammation in the CNS, serve as likely candidates in initiating pathological inflammation and as an ideal point of therapeutic intervention. Glucose deprivation, as a component of the pathophysiology of ischemia or occurring transiently in diabetes, may serve to modify microglial function contributing to inflammatory injury...
February 7, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28168592/improving-perinatal-mental-health-care-for-women-veterans-description-of-a-quality-improvement-program
#12
Jodie G Katon, Lacey Lewis, Selma Hercinovic, Amanda McNab, John Fortney, Susan M Rose
Purpose We describe results from a quality improvement project undertaken to address perinatal mental healthcare for women veterans. Description This quality improvement project was conducted in a single VA healthcare system between 2012 and 2015 and included screening for depressive symptoms with the Edinburgh Postnatal Depression Scale (EPDS) three times during the perinatal period, a dedicated maternity care coordinator (MCC), an on-site clinical social worker, and an on-site obstetrician/gynecologist (Ob/gyn)...
February 6, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28167438/a-more-rational-theory-driven-approach-to-analysing-the-factor-structure-of-the-edinburgh-postnatal-depression-scale
#13
Zoltan Kozinszky, Annamária Töreki, Emőke A Hompoth, Robert B Dudas, Gábor Németh
We endeavoured to analyze the factor structure of the Edinburgh Postnatal Depression Scale (EPDS) during a screening programme in Hungary, using exploratory (EFA) and confirmatory factor analysis (CFA), testing both previously published models and newly developed theory-driven ones, after a critical analysis of the literature. Between April 2011 and January 2015, a sample of 2967 pregnant women (between 12th and 30th weeks of gestation) and 714 women 6 weeks after delivery completed the Hungarian version of the EPDS in South-East Hungary...
January 23, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28167151/validation-of-the-intuitive-eating-scale-for-pregnant-women
#14
Sajeevika Saumali Daundasekara, Anitra Danielle Beasley, Daniel Patrick O'Connor, McClain Sampson, Daphne Hernandez, Tracey Ledoux
Pre-pregnancy maladaptive eating behaviors have predicted inadequate or excess gestational weight gain and poor dietary intake during pregnancy, but little is known about effects of pre-pregnancy adaptive eating behaviors on pregnancy outcomes. The purpose of this study was to produce a valid and reliable measure of adaptive pre-pregnancy eating behaviors for pregnant women using the Intuitive Eating Scale. Data were collected from 266 pregnant women, aged 18 and older who were attending a private prenatal clinic at Texas Children's Hospital Pavilion for Women in Houston, TX using self-administered questionnaires...
February 3, 2017: Appetite
https://www.readbyqxmd.com/read/28155572/exploring-the-role-of-microglia-in-cortical-spreading-depression-in-neurological-disease
#15
Mamoru Shibata, Norihiro Suzuki
Microglia play a pivotal role in innate immunity in the brain. During development, they mature from myeloerythroid progenitor cells in the yolk sac and colonize the brain to establish a resident population of tissue macrophages. In the postnatal brain, they exert phagocytosis and induce inflammatory response against invading pathogens. Microglia also act as guardians of brain homeostasis by surveying the microenvironment using motile processes. Cortical spreading depression (CSD) is a slowly propagating (2-5 mm/min) wave of rapid, near-complete depolarization of neurons and astrocytes followed by a period of electrical suppression of a distinct population of cortical neurons...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28150173/implementation-of-routine-postpartum-depression-screening-and-care-initiation-across-a-multispecialty-health-care-organization-an-18-month-retrospective-analysis
#16
April Lind, Sara Richter, Cheryl Craft, Alice C Shapiro
Objectives Postpartum depression (PPD) affects approximately 10-20% of all mothers after giving birth. Adequate screening and follow-up care for the postpartum mother with depression is an essential component of quality care in this population. The purpose of this quality improvement project was to evaluate the quality and quantity of a postnatal PPD screening program and the subsequent initiation of needed PPD treatment in an integrated health system. Methods After implementing a standardized PPD screening process, we conducted an 18-month retrospective study of patient visits that required a PPD screen...
February 1, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28143768/long-lasting-effects-of-fluoxetine-and-or-exercise-augmentation-on-bio-behavioural-markers-of-depression-in-pre-pubertal-stress-sensitive-rats
#17
Jacobus C Schoeman, Stephanus F Steyn, Brian H Harvey, Christiaan B Brink
Juvenile depression is of great concern with only limited treatment currently approved. Delayed onset of action, low remission and high relapse rates, and potential long-lasting consequences further complicates treatment and highlights the need for new treatment options. Studies reporting on long-lasting effects of early-life treatment have reported conflicting results, with the pre-adolescent period mostly overlooked. The anti-depressive effect of exercise, as a possible treatment option or augmentation strategy, is dependent on age and exercise intensity...
January 29, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28143536/the-impact-of-resilience-on-psychological-outcomes-in-women-with-threatened-premature-labor-and-spouses-a-cross-sectional-study-in-southwest-china
#18
Chunhua Nie, Qin Dai, Ren Zhao, Yushu Dong, Yushan Chen, Hui Ren
BACKGROUND: Threatened premature labor (TPL) is a severe obstetric complication which affects the mental and physical health of both the mother and fetus. Family resilience may have protective role against psychological distress in women experiencing these pregnancy complications. There may be resilience related risk factors in TPL women, and interplays may exist among psychological variables and within couples. This study aims to examine psychological outcomes influenced by different levels of resilience, and explore psychological interactions in TPL women, spouses, and between women and spouses...
January 31, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28135275/validity-and-acceptability-of-kimberley-mum-s-mood-scale-to-screen-for-perinatal-anxiety-and-depression-in-remote-aboriginal-health-care-settings
#19
Julia V Marley, Jayne Kotz, Catherine Engelke, Melissa Williams, Donna Stephen, Sudha Coutinho, Stephanie K Trust
BACKGROUND: The Edinburgh Postnatal Depression Scale (EPDS) is widely recommended for perinatal anxiety and depression screening. However, many Aboriginal women find EPDS language complex and confusing, and providers find using it with Aboriginal women challenging. The two part Kimberley Mum's Mood Scale (KMMS) was developed to improve screening: Part 1 is a Kimberley version of EPDS; Part 2 is a psychosocial tool that enables contextualisation of Part 1 scores. We aimed to determine if KMMS is a valid and acceptable method of identifying Kimberley Aboriginal perinatal women at risk of anxiety or depressive disorders compared to a semi-structured clinical interview...
2017: PloS One
https://www.readbyqxmd.com/read/28132000/computerised-cognitive-behavioural-therapy-for-depression-in-adolescents-feasibility-results-and-4-month-outcomes-of-a-uk-randomised-controlled-trial
#20
Barry Wright, Lucy Tindall, Elizabeth Littlewood, Victoria Allgar, Paul Abeles, Dominic Trépel, Shehzad Ali
OBJECTIVES: Computer-administered cognitive-behavioural therapy (CCBT) may be a promising treatment for adolescents with depression, particularly due to its increased availability and accessibility. The feasibility of delivering a randomised controlled trial (RCT) comparing a CCBT program (Stressbusters) with an attention control (self-help websites) for adolescent depression was evaluated. DESIGN: Single centre RCT feasibility study. SETTING: The trial was run within community and clinical settings in York, UK...
January 27, 2017: BMJ Open
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