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Postnatal depression

Charlotte Holm, Lars L Thomsen, Jens Langhoff-Roos
BACKGROUND AND OBJECTIVES: To explore if intravenous iron isomaltoside (Monofer® ) leads to a better relief of fatigue than current treatment practice with oral iron in women suffering from severe fatigue after postpartum hemorrhage. MATERIALS AND METHODS: This is a subanalysis of a single-center, open-label, randomized controlled trial conducted in women suffering from postpartum hemorrhage. Participants were randomized 1:1 to 1200 mg iron isomaltoside or current treatment practice with oral iron...
March 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
Laura Pogliani, Sara Baldelli, Dario Cattaneo, Paola Pileri, Emilio Clementi, Irene Cetin, M D Gianvincenzo Zuccotti
OBJECTIVE: Selective serotonin reuptake inhibitors are commonly used for the treatment of pregnancy-related and postnatal depression. However, only a few studies have evaluated the passage of these drugs into human milk, often with conflicting results. Here, we sought to evaluate the passage of selective serotonin reuptake inhibitors into human milk in the first days after delivery and their potential association with neonatal outcomes. STUDY DESIGN: The passage of selective serotonin reuptake inhibitors into human milk was expressed both as percentage of milk-to-plasma ratio of drug concentrations and as the relative infant dose...
March 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
Omotayo Bernard, Roger C Gibson, Affette McCaw-Binns, Jody Reece, Charlene Coore-Desai, Sydonnie Shakespeare-Pellington, Maureen Samms-Vaughan
BACKGROUND: Antenatal depression is associated with adverse maternal and infant well-being. However, compared to postpartum depression, it has been less frequently explored globally or in Jamaica. This study aimed to determine the prevalence of, and factors associated with, antenatal depressive symptoms among Jamaican women in order to inform policy and build interventions that could improve their management and reduce their negative consequences. METHODS: This secondary analysis of data from the second Jamaican Birth Cohort Study (JA-Kids Birth Cohort) included 3,517 women enrolled during pregnancy...
2018: PloS One
Štefica Mikšić, Maja Miškulin, Brankica Juranić, Željko Rakošec, Aleksandar Včev, Dunja Degmečić
BACKGROUND: Pregnant women experience a set of biological and psychological disturbances. The aim of this study was to assess the appearance of depressive symptoms and suicidal thoughts in pregnant women during the third trimester of pregnancy. SUBJECTS AND METHODS: A total of 110 pregnant women were included in the study. All of them filled out an anonymous questionnaire about sociodemographic data, Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI)...
March 2018: Psychiatria Danubina
Tiffany Field
The increasing prevalence of postnatal anxiety highlights the need for summarizing the recent research on this condition to inform screening and intervention efforts. This narrative review of the literature was derived from a search on PubMed and PsycINFO for papers published since 2010. The demographic risk factors for postnatal anxiety include being a young mother, having more education and being employed. Childbirth risk factors include being primiparous in one sample and multiparous in another, caesarean delivery, fear of the birth and of death during delivery, lack of control during labor, low self-confidence for the delivery and the delivery staff, and premature delivery...
March 12, 2018: Infant Behavior & Development
Tao Tan, Wei Wang, Haitao Xu, Zhilin Huang, Yu Tian Wang, Zhifang Dong
Patients with autism spectrum disorder (ASD) display abnormalities in neuronal development, synaptic function and neural circuits. The imbalance of excitatory and inhibitory (E/I) synaptic transmission has been proposed to cause the main behavioral characteristics of ASD. Repetitive transcranial magnetic stimulation (rTMS) can directly or indirectly induce excitability and synaptic plasticity changes in the brain noninvasively. However, whether rTMS can ameliorate autistic-like behaviors in animal model via regulating the balance of E/I synaptic transmission is unknown...
2018: Frontiers in Cellular Neuroscience
Shefaly Shorey, Cornelia Chee, Yap-Seng Chong, Esperanza Debby Ng, Ying Lau, Cindy-Lee Dennis
BACKGROUND: Multiple international agencies, including the World Health Organization and the International Monetary Fund, have emphasized the importance of maternal mental health for optimal child health and development. Adequate social support is vital for the most vulnerable to postpartum mood disorders. Hence, an urgent need for sustainable social support programs to aid mothers ease into their new parenting role exists. OBJECTIVE: This study protocol aims to examine the effectiveness of a technology-based peer support intervention program among mothers at risk for postnatal depression in the early postpartum period...
March 14, 2018: JMIR Research Protocols
Nancy Byatt, Lucille Cox, Tiffany A Moore Simas, Nisha Kini, Kathleen Biebel, Padma Sankaran, Holly A Swartz, Linda Weinreb
To elucidate (1) the challenges associated with under-recognition of bipolar disorder in obstetric settings, (2) barriers pregnant and postpartum women with bipolar disorder face when trying to access psychiatric care, and (3) how obstetric settings can identify such women and connect them with mental health services. Structured, in-depth interviews were conducted with 25 pregnant and postpartum women recruited from obstetric practices who scored ≥ 10 on the Edinburgh Postnatal Depression Scale and met DSM-IV criteria for bipolar disorder I, II, or not otherwise specified using the Mini International Neuropsychiatric Interview...
March 13, 2018: Archives of Women's Mental Health
Stephen Matthey, Frances Bilbao
BACKGROUND: Routine screening for emotional health difficulties in women during pregnancy is now advocated in several countries. There is a need therefore to compare the performance of different self-report measures to accomplish this. This study reports on the comparative performance of two such measures- the well-established PHQ-2, which aims to detect depression, and the more recent MGMQ, which aims to detect a wide array of negative emotions. METHOD: Women (N = 2292) attending a public hospital antenatal clinic over a 14-month period completed the two measures, either on their own (72%), verbally administered by the midwife (25%), or with an interpreter (3%)...
February 27, 2018: Journal of Affective Disorders
S Debruyne, A Ruiz-González, E Artiles-Ortega, B Ampe, W Van Den Broeck, E De Keyser, L Vandaele, K Goossens, V Fievez
The aim of this study was to investigate the methane (CH4) reducing potential of a combination of pre- and/or postnatal treatment with coconut oil medium chain fatty acids (CO MCFA) in goat kids. The hypothesis is that influencing rumen function during early life has more chances for success than in the adult life, related to the resilience of the mature rumen microbiota. Forty-eight pregnant does were split into 2 experimental groups: treated does (D+) received 40 g/d of CO MCFA in a test compound feed, while control does (D-) received a control compound feed, during the last 3 wk of gestation...
February 24, 2018: Journal of Animal Science
Somayeh Ramezani, Ahmad Khosravi, Zahra Motaghi, Azam Hamidzadeh, Seyed Abbas Mousavi
OBJECTIVE: The aim of this study was to evaluate the effect of cognitive-behavioural approach and solution-focused counselling on prevention of postpartum depression in nulliparous pregnant women. BACKGROUND: Maternity blues is a common disorder and postpartum depression is a serious disorder. Therefore, the use of preventive measures and timely intervention is of particular importance. METHODS: In this randomised clinical trial, 85 nulliparous pregnant women at 30-35 weeks were randomly divided into three groups: cognitive-behavioural counselling (n = 25), solution-focused counselling (n = 25) and control (n = 35)...
April 2017: Journal of Reproductive and Infant Psychology
Joana Pereira, Raquel Pires, Maria Cristina Canavarro
OBJECTIVE: To compare the depressive symptoms and quality of life (QoL) among adolescents (<20 years) and adult women who have had an abortion and to explore individual, social, relational and decision-making explanatory factors for (mal)adjustment in each group. BACKGROUND: International findings are not consistent regarding the presence of negative psychosocial outcomes after abortion or about the explanatory factors for occurrence among adolescents and adult women...
April 2017: Journal of Reproductive and Infant Psychology
Ruth Carter, Fiona Cust, Elizabeth Boath
OBJECTIVE: To explore the lived experiences of peer support workers (PSWs) during their intervention with mothers suffering from postnatal depression (PND). BACKGROUND: Postnatal depression is a major public health concern affecting approximately 13% of women worldwide. There is evidence within recent literature that peer support may have a positive effect upon women suffering with PND. METHODS: Written data from the PSW's logbooks, interviews and supervisory sessions was collected and thematically analysed...
December 26, 2017: Journal of Reproductive and Infant Psychology
N Séjourné, R Sanchez-Rodriguez, A Leboullenger, S Callahan
INTRODUCTION: Maternal burn-out is a psychological, emotional and physiological condition resulting from the accumulation of various stressors characterised by a moderate but also a chronic and repetitive dimension. Little research has focused on this syndrome. OBJECTIVE: The current study aims to assess maternal burn-out rate and to identify factors associated with this state of exhaustion. METHOD: 263 French mothers aged between 20 and 49 years answered five scales quantifying maternal burn-out, perceived social support, parental stress, depression and anxiety symptoms and history of postnatal depression...
February 21, 2018: Journal of Reproductive and Infant Psychology
Stavros I Iliadis, Alkistis Skalkidou, Hanna Ranstrand, Marios K Georgakis, Cathrine Axfors, Fotios C Papadopoulos
Introduction: Postpartum depression predisposes to maternal affective and somatic disorders. It is important to identify which women are at an increased risk of subsequent morbidity and would benefit from an intensified follow-up. Self-harm thoughts (SHTs), with or without other depressive symptomatology, might have prognostic value for maternal health beyond the postpartum period. Aim: This study is to investigate the somatic and psychiatric morbidity of postpartum women with SHTs, with or without other depressive symptoms, over a 7-year follow-up period...
2018: Frontiers in Public Health
Lin Ru Wang, Seung-Soo Baek
Social isolation is known to precipitate depression-like symptoms in rodents and has emerged as a dependable paradigm to screen the behavioral and neurobiological changes observed in humans. In the present study, the undying mechanisms of treadmill exercise on social isolation-induced depression was evaluated. The rat pups in the social isolation groups were housed individually. The social isolation procedures started on the postnatal day 14. The rat pups in the exercise groups were forced to run on treadmill for 30 min once a day from postnatal day 21 to postnatal day 34...
February 2018: Journal of Exercise Rehabilitation
H C Gustafsson, P G Grieve, E A Werner, P Desai, C Monk
Maternal perinatal depression exerts pervasive effects on the developing brain, as evidenced by electroencephalographic (EEG) patterns that differ between children of women who do and do not meet DSM or ICD diagnostic criteria. However, little research has examined if the same EEG pattern of right-frontal alpha asymmetry exists in newborns and thus originates in utero independent of postnatal influences, and if depressive symptoms are associated with this neural signature. Utilizing 125-lead EEG (n=18), this study considered clinician-rated maternal prenatal depressive symptoms in relation to newborn EEG...
March 6, 2018: Journal of Developmental Origins of Health and Disease
Erin J Rotheram-Fuller, Mark Tomlinson, Aaron Scheffler, Thomas W Weichle, Panteha Hayati Rezvan, Warren Scott Comulada, Mary Jane Rotheram-Borus
OBJECTIVE: The consequences of maternal depressed mood on children's growth, health, and cognitive and language development are examined over the first 3 years of life. METHOD: Pregnant women in 24 periurban township neighborhoods in Cape Town, South Africa (N = 1,238 mothers) were randomized by neighborhood to a home visiting intervention or a standard care condition. Reassessments were conducted for 93%-85% of mothers at 2-weeks, 6-, 18-, and 36-months postbirth...
March 2018: Journal of Consulting and Clinical Psychology
Abdullah H Alqahtani, Kholoud Al Khedair, Reem Al-Jeheiman, Haifa A Al-Turki, Nourah H Al Qahtani
Background: Anxiety and depression during the antenatal period is a growing problem with major effects on the mother, the developing fetus, and the neonate. Objectives: To assess the prevalence of anxiety and depression during pregnancy in women attending the hospital for antenatal care and assess the associated factors. Methods: This is a prospective cohort study conducted in the University Hospital of Imam Abdulrahman Bin Faisal University...
2018: International Journal of Women's Health
Jonathan Schaffir, Anne Kunkler, Courtney D Lynch, Jason Benedict, Loriana Soma, Andrew Doering
OBJECTIVE: Postpartum depression may be associated with higher levels of postpartum pain, but the association with discomfort in general is unclear. We sought to describe an association between postpartum mood disturbances and quantitatively measured physical symptoms at the time of the routine postpartum encounter. METHODS: We designed a novel quantitative measurement of postpartum symptoms, the Postpartum Symptom Inventory (PSI), to allow comparison to scores of postpartum mood...
April 2018: Journal of Psychosomatic Research
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