keyword
https://read.qxmd.com/read/38388076/second-radioiodine-treatment-in-patients-with-differentiated-thyroid-carcinoma-causes-and-effects
#1
JOURNAL ARTICLE
María de Las Nieves Sicilia Pozo, Francisco José Pena Pardo, Mariano Amo Salas, Marcos Cruz Montijano, Javier Torres Hernández, Amanda Padilla Bermejo, Cristina Montalbán Méndez, María Zhao Montero, Ángel Soriano Castrejón, Ana María García Vicente
INTRODUCTION: Patients with incomplete response to initial therapy of thyroid cancer can be managed with ongoing observation or potentially additional therapies. Our aim was to assess the effect of a second radioactive iodine treatment (RAIT) and its relationship with causes and clinical variables. MATERIAL AND METHODS: Patients undergoing a second RAIT for biochemical or structural incomplete response to initial therapy of DTC were retrospectively included (n=120)...
January 2024: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/38373618/neurofibroma-of-the-vagus-nerve-as-an-incidental-finding-during-left-modified-radical-neck-dissection-for-papillary-thyroid-cancer
#2
JOURNAL ARTICLE
Aitor Redondo Expósito, María Pilar Salvador Egea, Cristina Erce García, Alfonso Vázquez Miguez
No abstract text is available yet for this article.
February 17, 2024: Cirugia española
https://read.qxmd.com/read/38331249/comparison-of-body-iodine-pool-assessment-methods-before-radioiodine-therapy
#3
JOURNAL ARTICLE
Mustafa Genc, Aslihan Yildirim, Nilufer Yildirim
INTRODUCTION AND OBJECTIVES: Radioactive iodine therapy (RAIT) is recommended to reduce the risk of recurrence and metastasis in patients with intermediate-high risk differentiated thyroid cancer (DTC). In preparation for RAIT, stimulation of thyroid-stimulating hormone and reduction of body iodine pool are important for treatment success. For this purpose, patients are asked to reduce their iodine intake before RAIT, and the body iodine pool can be evaluated by measuring iodine excretion in urine before treatment...
February 6, 2024: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/37479461/thyroglossal-duct-cyst-carcinoma-case-series-management-strategy-and-outcomes
#4
JOURNAL ARTICLE
Aleix Rovira, Aina Brunet, Jean Pierre Jeannon, Paul V Carroll, Phil Touska, Fahim Hassan, Ann Sandison, Ricard Simo
OBJECTIVE: To review the clinical presentation, diagnosis, pathology and management strategies in a modern cohort of patients with thyroglossal duct cyst carcinoma. STUDY DESIGN: Retrospective case series following PROCESS Guidelines. SETTING: Comprehensive cancer centre. METHODS: Data recorded included: gender, age at diagnosis, clinical presentation, thyroid function, diagnostic investigations, cytological results, final histology, staging and follow up status...
2023: Acta otorrinolaringologica española
https://read.qxmd.com/read/37394352/foreign-body-reactions-to-oxidized-cellulose-in-the-follow-up-of-thyroid-cancer
#5
JOURNAL ARTICLE
Fernando Sebastian-Valles, José Luis Muñoz-de-Nova, Marcos Lahera Vargas
No abstract text is available yet for this article.
June 30, 2023: Medicina Clínica
https://read.qxmd.com/read/37002122/thyroid-carcinoma-in-elderly-people-characterization-using-big-data-tools
#6
JOURNAL ARTICLE
Juan J Díez, Luis Cabrera, Pedro Iglesias, María Benavent, Guillermo López, Guillermo Argüello, Alejandro Parralejo, Alberto López-Velázquez
OBJECTIVE: To determine the clinical-histological data associated comorbidities and the use of health resources of elderly patients with thyroid cancer. METHODS: An observational, retrospective study was carried out using data from the electronic medical record (EMR) of the Hospital Universitario Puerta de Hierro Majadahonda (Madrid, Spain). The information was extracted using artificial intelligence techniques and analysed using the Savana Manager 3.0 software...
March 29, 2023: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/36906068/clinical-pathway-of-metabolic-therapy-with-131-i-in-differentiated-thyroid-cancer
#7
JOURNAL ARTICLE
I Blanco Saiz, E Anda Apiñániz, J Pineda Arribas, F Caudepón Moreno, A Fernández Iglesias, M Huarte Jiménez, A I de Miguel Muñoz, M I Irigoyen Aristorena, E Goñi Gironés
Clinical Pathways are care plans that are applied to clinical processes with a predictable course, with the intention of protocolizing these processes and reducing the variability in their management. Our objective was to develop a clinical pathway for 131 I metabolic therapy in its application to differentiated thyroid cancer. A work team was organized consisting of doctors (Endocrinology and Nuclear Medicine), nursing staff (Hospitalization Unit and Nuclear Medicine), Radiophysics and the Clinical Management and Continuity of Care Support Service...
March 9, 2023: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/36787604/volumen-plaquetario-medio-e-%C3%A3-ndice-de-plaquetas-linfocitos-como-factores-de-pron%C3%A3-stico-en-c%C3%A3-ncer-papilar-de-tiroides
#8
JOURNAL ARTICLE
Jesús E Mendoza-Hernández, Luis M Hurtado-López, Erich O P Basurto-Kuba, Edgar R Montes de Oca-Durán, Felipe R Zaldívar-Ramírez, Abraham Pulido-Cejudo
BACKGROUND: Papillary thyroid cancer is the most common endocrine neoplasia. There are prognostic factors that establish risk of recurrence and mortality; however, patients considered low risk may have a less favorable evolution and hence the importance of finding new markers. OBJECTIVE: To assess whether the mean platelet volume (MPV) and the platelet-lymphocyte index (PLI) show a relationship with the clinical staging in papillary thyroid cancer. METHOD: Retrospective, observational and analytical study...
2023: Cirugia y Cirujanos
https://read.qxmd.com/read/36764748/preoperative-serum-inflammation-based-scores-in-medullary-thyroid-cancer
#9
JOURNAL ARTICLE
Ana Abrantes Figueiredo, Susana Esteves, Margarida Maria Moura, Pedro Marques, Joana Simões-Pereira, Valeriano Leite
INTRODUCTION: Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) are prognostic factors in several tumours, though little is known in medullary thyroid cancer (MTC). OBJECTIVE: To evaluate the association between preoperative NLR, PLR and SII with MTC clinicopathological and molecular features, and their predictive value for lymph node and distant metastasis. METHODS: We retrospectively analysed 75 patients with MTC who underwent surgery at our institution...
January 2023: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/36503171/role-of-131-i-in-low-risk-differentiated-thyroid-cancer
#10
REVIEW
Juan Antonio Vallejo
Differentiated thyroid cancer (DTC) is the most frequent endocrine neoplasm, with an increase in recent decades. Papillary carcinoma is the most frequent histological subtype and a large number of cases are related to tumors of small size and with little clinical repercussion, detected incidentally or as a consequence of the availability of diagnostic techniques. The "good prognosis" of the majority of cases has maintained for years the controversy in the approach to these patients, especially in two basic aspects of the therapeutic protocol: surgery and the administration of radioiodine...
2023: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/36472864/risk-factors-for-hypocalcemia-after-total-thyroidectomy
#11
JOURNAL ARTICLE
Ariel Shuchleib-Cung, Jose Antonio Garcia-Gordillo, Aldo Ferreira-Hermosillo, Moises Mercado
BACKGROUND: Hypocalcemia is a common complication of total thyroidectomy; transient hypocalcemia has been reported in up to 68% of the patients. MATERIALS AND METHODS: Chart review of all patients undergoing total thyroidectomy from 2016 to 2020. Clinical, biochemical, and pathological information was registered. We sought correlations between the different variables and the occurrence of post-operative hypocalcemia. This is a retrospective study carried out at a tertiary care teaching hospital...
2022: Cirugia y Cirujanos
https://read.qxmd.com/read/36470820/evolution-of-suppressing-tsh-therapy-at-diagnosis-and-in-the-long-term-follow-up-in-a-cohort-of-differentiated-thyroid-cancer
#12
JOURNAL ARTICLE
Gonzalo Díaz-Soto, Pablo Fernández-Velasco, Beatriz Torres Torres, Juan José López Gómez, Susana García Calvo, Daniel de Luis Román
INTRODUCTION: To evaluate the adequacy of TSH suppression therapy (TSHst) at the first disease assessment and the last follow-up visit. METHODS: Retrospective observational study of those patients under follow-up of DTC in a reference hospital. RESULTS: 216 patients (79.2% women) were evaluated, with a mean age 59.0 ± 13.1 years-old and a mean follow-up of 6.9 ± 4.3 years. 88.4% were papillary carcinomas...
December 2, 2022: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/36470645/thyroglobulin-antibodies-trend-over-time-and-clinical-impact-in-differentiated-thyroid-carcinoma-with-and-without-radioiodine-ablation
#13
JOURNAL ARTICLE
María Laura Iglesias, Juan Matías Calabretta, Osvaldo Coggiola, Inés Califano
INTRODUCTION: Thyroglobulin antibodies (TgAb) trend may be considered a surrogate marker for thyroglobulin in differentiated thyroid carcinoma. The aim of this study is to analyse, in cases with positive TgAb, trend over time and its relationship with response to treatment. MATERIAL AND METHODS: Retrospective and descriptive study of 100 patients with differentiated thyroid carcinoma and positive TgAb (measured by electrochemoluminiscense) after thyroidectomy. Assessment of response to initial treatment was performed 6-24 months after surgery...
November 2022: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/36257572/iatrogenic-chylous-fistula-after-total-thyroidectomy-for-papillary-thyroid-cancer
#14
JOURNAL ARTICLE
María Asunción Acosta-Mérida, Laura Cano-Contreras, Zaida Brito-Pérez, María Del Mar Callejón-Cara
No abstract text is available yet for this article.
September 2023: Cirugia española
https://read.qxmd.com/read/36155103/clinical-behaviour-of-papillary-thyroid-cancer-oncocytic-variant-stage-matched-comparison-versus-classical-and-tall-cell-variant-papillary-thyroid-cancer
#15
JOURNAL ARTICLE
K Okuyucu, S Ince, A Cinar, H San, M Samsum, N Dizdar, E Alagoz, I Demirci, M Ozkara, B Gunalp, A O Karaçalıoglu
OBJECTIVE: Papillary thyroid cancer (PTC) has many variants and most of them are mild tumors. Oncocytic variant (OV) is a rare subtype of PTC. There are controversial results about its prognosis in the literature. We investigated its aggressivity and clinical course by comparing it with classical variant (CV) and tall cell variant (TV) of PTC over a stage-matched design. MATERIAL AND METHODS: Pure 100 OV, 71TV and 1219 CV were included in this retrospective cohort study...
September 22, 2022: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/35894740/ret-gene-mutational-diagnosis-and-precision-medicine-in-mexico
#16
JOURNAL ARTICLE
Mariana A Martínez-Castillo, María E Medrano-Ortiz de Zárate, Alejandra Valenzuela-Pérez, Jorge A Ruiz-Romero, Félix O Quijano-Castro, Mauricio Salcedo
Precision medicine is a reality in some diseases; it supports the development of accurate and specific diagnostic methods, new drugs and molecules. Our research team in Mexico, made up of clinical and biomedical researchers, has been performing free RET gene mutational diagnosis for medullary thyroid cancer and multiple endocrine neoplasia (MEN) 2 and 3 for 20 years. RET pathogenic variants in the Mexican population are consistent with reported data: most common mutations are 634/NEM2 and 918/NEM3. Currently, new nanobiotechnology methods are being developed for this type of determination in order to obtain faster, simpler, more sensitive and specific results applicable in all types of laboratories...
2022: Gaceta Médica de México
https://read.qxmd.com/read/35676051/usefulness-of-ultrasound-guided-core-biopsy-in-thyroid-nodules-with-inconclusive-fine-needle-aspiration-biopsy-findings
#17
JOURNAL ARTICLE
R Cortázar-García, M D Martín-Escalante, L Robles-Cabeza, C Martínez-Santos
OBJECTIVES: To determine the diagnostic performance of ultrasound-guided core-needle biopsy in thyroid nodules after two inconclusive fine-needle aspiration biopsies. To assess the complications of core-needle biopsy. To analyze the reliability of diagnoses obtained with core-needle biopsy. To measure the economic impact of avoiding lobectomies in patients with benign core-needle biopsy findings. MATERIAL AND METHODS: This retrospective study reviewed 195 core-needle biopsies in 178 patients...
May 2022: Radiología
https://read.qxmd.com/read/34936254/regulation-of-nuclear-medicine-services-perception-of-the-problems-and-challenges-in-colombia-for-the-approach-to-cancer
#18
JOURNAL ARTICLE
Eliana Marcela Murcia, Johana Andrea Lineros, Jairo Aguilera, Carlos Eduardo Granados, María Cristina Martínez, Nathaly Barbosa
Introduction: Colombia has modified the nuclear medicine norms that impact the administration of radioactive iodine therapy in the treatment of thyroid cancer. Objective: To identify the areas of agreement regarding the issue, as well as the current and emergent requirements associated with the normative for the operation of nuclear medicine services that have an impact on the care of patients with thyroid cancer in Colombia. Materials and methods: We conducted a two-round Delphi study for each expert, clinical, and regulatory group...
December 15, 2021: Biomédica: Revista del Instituto Nacional de Salud
https://read.qxmd.com/read/34924161/ultrasound-criteria-eu-tirads-to-identify-thyroid-nodule-malignancy-risk-in-adolescents-correlation-with-cyto-histological-findings
#19
JOURNAL ARTICLE
Diego Yeste Fernández, Elizabeth Vega Amenabar, Ana Coma Muñoz, Larry Arciniegas Vallejo, María Clemente León, Marina Planes-Conangla, Carmela Iglesias Felip, Constantino Sábado Álvarez, Gabriela Guillén Burrieza, Ariadna Campos-Martorell
INTRODUCTION: Thyroid nodule (TN) harbouring a thyroid carcinoma are more common in paediatric than adult patients. In paediatric population, the evaluation of a TN should require specific paediatric tools for its diagnostic and therapeutic management. High-resolution ultrasonography and cytological evaluation after fine-needle aspiration biopsy (FNAB) remain the cornerstones of evaluation of TN. OBJECTIVES: To evaluate in paediatric TN for the first time the usefulness and precision of the ultrasound criteria defined by the "Thyroid Imaging Reporting and Data System (EU-TIRADS) 2017 in adults" to establish the ultrasound indication for the practice of FNAB and stratify the risk of malignancy...
December 2021: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/34924156/assessment-of-the-utility-of-measuring-thyroglobulin-mrna-levels-by-quantitative-real-time-pcr-in-the-follow-up-of-differentiated-thyroid-cancer-patients
#20
JOURNAL ARTICLE
María Fabiana Russo-Picasso, María Pía Serra, María Lorena Viale, María Celeste Puga, Sergio Terrasa, Andrea Elina Kozak, Inés Califano, Luis Alejandro Boccalatte, Analía Stigliano, Patricia Fainstein-Day
INTRODUCTION: The determination of thyroglobulin levels by immunoassay and imaging studies is subject to interference by antithyroglobulin antibodies in up to 30% of cases, suggesting a need to find alternative methods for the follow-up of a significant number of thyroid cancer patients. OBJECTIVES: Assess the sensitivity, specificity, and predictive values of thyroglobulin messenger RNA levels measured by quantitative Real Time-PCR (qRT-PCR) in the blood of patients followed for differentiated thyroid cancer...
December 2021: Endocrinología, diabetes y nutrición
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