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https://www.readbyqxmd.com/read/29471524/enteric-methane-production-and-ruminal-fermentation-of-forage-brassica-diets-fed-in-continuous-culture
#1
S Leanne Dillard, Ana I Roca-Fernández, Melissa D Rubano, Kyle R Elkin, Kathy J Soder
The aim of the current study was to determine nutrient digestibility, VFA production, N metabolism, and CH4 production of canola (Brassica napus L.), rapeseed (B. napus L.), turnip (B. rapa L.), and annual ryegrass (Lolium multiflorum Lam.) fed with orchardgrass (Dactylis glomerata L.) in continuous culture. Diets were randomly assigned to fermentors in a 4 × 4 Latin square design using 7 d for adaptation and 3 d for collection. Diets were: 1) 50% orchardgrass + 50% annual ryegrass (ARG); 2) 50% orchardgrass + 50% canola (CAN); 3) 50% orchardgrass + 50% rapeseed (RAP); and 4) 50% orchardgrass + 50% turnip (TUR)...
February 17, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471514/management-of-anaemia-and-iron-deficiency-in-patients-with-cancer-esmo-clinical-practice-guidelines
#2
M Aapro, Y Beguin, C Bokemeyer, M Dicato, P Gascón, J Glaspy, A Hofmann, H Link, T Littlewood, H Ludwig, A Österborg, P Pronzato, V Santini, D Schrijvers, R Stauder, K Jordan, J Herrstedt
No abstract text is available yet for this article.
February 20, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29471489/the-h-subunit-of-the-restriction-endonuclease-cgli-contains-a-prototype-dead-z1-helicase-like-motor
#3
Paulius Toliusis, Giedre Tamulaitiene, Rokas Grigaitis, Donata Tuminauskaite, Arunas Silanskas, Elena Manakova, Ceslovas Venclovas, Mark D Szczelkun, Virginijus Siksnys, Mindaugas Zaremba
CglI is a restriction endonuclease from Corynebacterium glutamicum that forms a complex between: two R-subunits that have site specific-recognition and nuclease domains; and two H-subunits, with Superfamily 2 helicase-like DEAD domains, and uncharacterized Z1 and C-terminal domains. ATP hydrolysis by the H-subunits catalyses dsDNA translocation that is necessary for long-range movement along DNA that activates nuclease activity. Here, we provide biochemical and molecular modelling evidence that shows that Z1 has a fold distantly-related to RecA, and that the DEAD-Z1 domains together form an ATP binding interface and are the prototype of a previously undescribed monomeric helicase-like motor...
February 20, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29471478/internet-delivered-cognitive-behavioral-therapy-for-insomnia-in-breast-cancer-survivors-a-randomized-controlled-trial
#4
Robert Zachariae, Ali Amidi, Malene F Damholdt, Cecilie D R Clausen, Jesper Dahlgaard, Holly Lord, Frances P Thorndike, Lee M Ritterband
Background: Insomnia is two to three times more prevalent in cancer survivors than in the general population, where it is estimated to be 10% to 20%. Cognitive-behavioral therapy for insomnia (CBT-I) is the recommended treatment for chronic insomnia, but meeting survivor needs remains a challenge. Internet-delivered CBT-I (iCBT-I) has been shown efficacious in otherwise healthy adults. We tested the efficacy of iCBT-I in breast cancer survivors with clinically significant sleep disturbance...
February 20, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29471465/effects-of-dietary-energy-level-and-intake-of-corn-by-product-based-diets-on-newly-received-growing-cattle-antibody-production-acute-phase-protein-response-stress-and-immunocompetency-of-healthy-and-morbid-animals
#5
T J Spore, S P Montgomery, E C Titgemeyer, G A Hanzlicek, C I Vahl, T G Nagaraja, K T Cavalli, W R Hollenbeck, R A Wahl, D A Blasi
Effects of dietary energy level and intake of corn by-product based diets on antibody production, acute phase protein response, stress, and immunocompetency of healthy and morbid newly received growing cattle were evaluated. Four dietary treatments were formulated to supply 0.99, 1.10, 1.21, and 1.32 Mcal NEg/ kg DM and were offered at 100%, 95%, 90%, and 85% of ad libitum based on 0.99/100 treatment intake, respectively. Thirty-two pens were utilized with approximately 12 animals/pen. Four animals from each pen (32/dietary treatment) were randomly selected and used to serve as a subset to monitor immune function and acute phase proteins following a split-plot design...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471429/comparison-of-3-methods-for-estimating-enteric-methane-and-carbon-dioxide-emission-in-nonlactating-cows
#6
M Doreau, M Arbre, Y Rochette, C Lascoux, M Eugène, C Martin
Among techniques for estimating enteric methane (CH4) emission by ruminants, open-circuit respiration chambers (OC), the use of a gas tracer (SF6) and the GreenFeed device (GF) are the most commonly used. In this study, we compared these techniques in 8 dry cows receiving a diet made of 70% hay and 30% concentrates given in limited and constant amounts, in a 15-week experiment. Two periods in free stalls for SF6 and GF and in chambers for OC were used; in addition, SF6 was determined in chambers for 1 period...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471421/class-3-semaphorins-modulate-the-invasive-capacity-of-rheumatoid-arthritis-fibroblast-like-synoviocytes
#7
Man Wai Tang, Beatriz Malvar Fernández, Simon P Newsom, Jaap D van Buul, Timothy R D J Radstake, Dominique L Baeten, Paul P Tak, Kris A Reedquist, Samuel García
Objective: Class 3 semaphorins regulate diverse cellular processes relevant to the pathology of RA, including immune modulation, angiogenesis, apoptosis and invasive cell migration. Therefore, we analysed the potential role of class 3 semaphorins in the pathology of RA. Methods: Protein and mRNA expression in RA synovial tissue, SF and fibroblast-like synoviocytes (FLS) were determined by immunoblotting and quantitative PCR (qPCR). RA FLS migration and invasion were determined using wound closure and transwell invasion assays, respectively...
February 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29471403/influence-of-distiller-s-dried-grains-with-solubles-on-ram-lamb-growth-and-reproductive-traits
#8
A R Crane, R R Redden, M S Crouse, J D Kirsch, P P Borowicz, J E Held, K C Swanson, C S Schauer
The hypothesis of this experiment was that increasing the inclusion level of distiller's dried grains (DDGS) in the diets would decrease semen quality but have no negative effects on growth performance. Following the removal of DDGS from the diet, it was hypothesized that the ram lambs would recover and become reproductively sound, independent of treatment. To test this hypothesis, Suffolk and Hampshire ram lambs (n = 112) were allocated to four treatments (n = 4 pens/treatment; 7 rams/pen) in a completely randomized design...
February 20, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471401/influence-of-tree-size-and-application-rate-on-expression-of-thiamethoxam-in-citrus-and-its-efficacy-against-diaphorina-citri-hemiptera-liviidae
#9
K W Langdon, R Schumann, L L Stelinski, M E Rogers
Neonicotinoids are a key group of insecticides used to manage Diaphorina citri Kuwayama (Hemiptera: Liviidae), in Florida citrus. Diaphorina citri is the vector of Candidatus Liberibacter asiaticus, the presumed causal agent of huanglongbing, a worldwide disease of citrus. A two-season field study was conducted to evaluate the effect of tree size and application rate on the expression of thiamethoxam in young citrus following application to the soil. D. citri adult and nymph abundance was also correlated with thiamethoxam titer in leaves...
February 20, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29471395/origin-and-composition-of-cell-free-dna-in-spent-medium-from-human-embryo-culture-during-preimplantation-development
#10
M Vera-Rodriguez, A Diez-Juan, J Jimenez-Almazan, S Martinez, R Navarro, V Peinado, A Mercader, M Meseguer, D Blesa, I Moreno, D Valbuena, C Rubio, C Simon
STUDY QUESTION: What is the origin and composition of cell-free DNA in human embryo spent culture media? SUMMARY ANSWER: Cell-free DNA from human embryo spent culture media represents a mix of maternal and embryonic DNA, and the mixture can be more complex for mosaic embryos. WHAT IS KNOWN ALREADY: In 2016, ~300 000 human embryos were chromosomally and/or genetically analyzed using preimplantation genetic testing for aneuploidies (PGT-A) or monogenic disorders (PGT-M) before transfer into the uterus...
February 20, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29471345/establishing-quality-assured-qa-laboratory-support-for-onchocerciasis-elimination-in-africa
#11
Joseph Shott, Camilla Ducker, Thomas R Unnasch, Charles D Mackenzie
An essential component in achieving accepted successful elimination of a disease or a pathogen involves the acquisition of quality-assured (QA) data that ultimately define the absence of infection or transmission in previously endemic areas. The acquisition of these essential data, in the case of onchocerciasis elimination, requires strong laboratory support for both testing and continuing evaluation/validation of the tools used for the required diagnostic and epidemiology procedures. There is also a need for standardization of the laboratory-based and field-based assays used across the onchocerciasis-endemic countries as well as continuing technical, fiscal and logistical support for laboratory activities...
March 1, 2018: International Health
https://www.readbyqxmd.com/read/29471127/targeting-cd14-on-blood-derived-cells-improves-intracortical-microelectrode-performance
#12
Hillary W Bedell, John K Hermann, Madhumitha Ravikumar, Shushen Lin, Ashley Rein, Xujia Li, Emily Molinich, Patrick D Smith, Stephen M Selkirk, Robert H Miller, Steven Sidik, Dawn M Taylor, Jeffrey R Capadona
Intracortical microelectrodes afford researchers an effective tool to precisely monitor neural spiking activity. Additionally, intracortical microelectrodes have the ability to return function to individuals with paralysis as part of a brain computer interface. Unfortunately, the neural signals recorded by these electrodes degrade over time. Many strategies which target the biological and/or materials mediating failure modes of this decline of function are currently under investigation. The goal of this study is to identify a precise cellular target for future intervention to sustain chronic intracortical microelectrode performance...
February 13, 2018: Biomaterials
https://www.readbyqxmd.com/read/29471114/reference-size-matching-whole-genome-amplification-and-fluorescent-labeling-as-a-method-for-chromosomal-microarray-analysis-of-clinically-actionable-copy-number-alterations-in-formalin-fixed-paraffin-embedded-tumor-tissue
#13
Shelly R Gunn, Shailin Govender, Cynthe L Sims, Aditi Khurana, Samuel Koo, Jayne Scoggin, Mathew W Moore, Philip D Cotter
Cancer genome copy number alterations (CNAs) assist clinicians in selecting targeted therapeutics. Solid tumor CNAs are most commonly evaluated in formalin-fixed, paraffin-embedded (FFPE) tissue by fluorescence in situ hybridization. Although fluorescence in situ hybridization is a sensitive and specific assay for interrogating pre-selected genomic regions, it provides no information about co-existing clinically significant copy number changes. Chromosomal microarray analysis is an alternative DNA-based method for interrogating genome-wide CNAs in solid tumors...
February 19, 2018: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/29471094/electrospinning-of-food-grade-nanofibres-from-whey-protein
#14
Jie Zhong, Saeed D Mohan, Alan Bell, Ann Terry, Geoffrey R Mitchell, Fred J Davis
In this study, electrospinning has been employed to produce micro to nano scale fibres of whey protein in order to investigate their potential for use in the food industry. Initially, spinning of pure whey protein proved challenging; so in order to facilitate the spinning of freshly prepared aqueous solutions, small amounts of polyethylene oxide (as low as 1% w/w in solution) were incorporated in the spinning solutions. The electrospun composite polyethylene-oxide/whey fibres exhibited diameters in the region of 100 to 400 nm, showing the potential to build fibre bundles from this size up...
February 19, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29471056/number-of-raised-steps-during-the-short-and-fast-step-test-a-functional-tool-to-assess-response-to-brief-and-intense-effort-involving-anaerobic-metabolism
#15
Davy Laroche, Morgane Mangin, Delphine Besson, Alexandre Naaim, Anaïs Gouteron, Jean-Marie Casillas
BACKGROUND: Although the initial anaerobic component of exercise adaptation is unavoidable, no specific functional test is available for use in routine non-sporting practice to evaluate it. OBJECTIVE: To assess the bioenergetic and biomechanical properties of the Short and Fast Step Test (SFST), which consists of walking up and down a step as many times as possible in 1minute and to analyse its ability to explore the initial anaerobic component of effort in comparison to a reference self-paced step test...
February 19, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29471021/does-male-preference-play-a-role-in-maintaining-female-limited-polymorphism-in-a-batesian-mimetic-butterfly
#16
E L Westerman, R Letchinger, A Tenger-Trolander, D Massardo, D Palmer, M R Kronforst
Female-limited polymorphism occurs in multiple butterfly species with Batesian mimicry. While frequency-dependent selection is often argued as the driving force behind polymorphism in Batesian mimicry systems, male preference and alternative female mating strategies may also influence the maintenance of multiple female forms. Through a series of behavioural assays with the female-limited Batesian mimetic butterfly Papilio polytes, we show that males prefer stationary mimetic females over stationary non-mimetic females, but weigh female activity levels more heavily than female wing pattern when choosing between active mimetic and active non-mimetic females...
February 19, 2018: Behavioural Processes
https://www.readbyqxmd.com/read/29470988/shear-dependent-fibrillogenesis-of-fibronectin-impact-of-platelet-integrins-and-actin-cytoskeleton
#17
Huong Nguyen, Khon Huynh, Volker R Stoldt
Soluble plasma fibronectin (Fn) with its inactive compact structure requires unfolding to assemble into active fibrils, which play a role in hemostasis and thrombosis. Fn fibril assembly involves Fn binding to cell receptors, biomechanical coupling of Fn to the cytoskeleton by integrins, exposure of self-assembly sites via contractile cell forces, and elongation of fibrils by Fn polymerization. In this report, we investigated the effect of platelet integrins and actin cytoskeleton on conformational changes of Fn induced by shear...
February 19, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29470960/establishment-of-reference-intervals-for-the-salivary-cortisol-circadian-cycle-by-electrochemiluminescence-eclia-in-healthy-adults
#18
Nadia Gagnon, Isabelle Fréchette, Pierre-Luc Mallet, Jean Dubé, Ghislaine Houde, Guy D Fink
OBJECTIVES: To determine salivary cortisol reference intervals in a healthy adult population, at 6 different time points during a 24-hour (h) period. METHODS: In a prospective study, salivary cortisol concentrations were measured upon waking, one-hour post-waking and at specific times of the day: at 12 h00, 16 h00, 20 h00 and midnight. Samples were analyzed by the first and second-generation electrochemiluminescence assays (ECLIA) from Roche Cobas Cortisol®...
February 19, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29470820/the-impact-of-intraoperative-re-resection-of-a-positive-bile-duct-margin-on-clinical-outcomes-for-hilar-cholangiocarcinoma
#19
Xu-Feng Zhang, Malcolm H Squires, Fabio Bagante, Cecilia G Ethun, Ahmed Salem, Sharon M Weber, Thuy Tran, George Poultsides, Andre Y Son, Ioannis Hatzaras, Linda Jin, Ryan C Fields, Matthew Weiss, Charles Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Carl R Schmidt, Timothy M Pawlik
BACKGROUND: The impact of re-resection of a positive intraoperative bile duct margin on clinical outcomes for resectable hilar cholangiocarcinoma (HCCA) remains controversial. We sought to define the impact of re-resection of an initially positive frozen-section bile duct margin on outcomes of patients undergoing surgery for HCCA. METHODS: Patients who underwent curative-intent resection for HCCA between 2000 and 2014 were identified at 10 hepatobiliary centers...
February 22, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29470810/diversity-of-anopheles-spp-diptera-culicidae-in-an-amazonian-urban-area
#20
I C Reis, C T Codeço, D C P Câmara, J J Carvajal, G R Pereira, E C Keppeler, N A Honório
The genus Anopheles encompasses several species considered as vectors of human infecting Plasmodium. Environmental changes are responsible for behavior changes in these vectors and therefore the pattern of malaria transmission. To better understand the dynamics of malaria transmission, this study aimed at identify the species of adult anophelines found in a malaria endemic urban area of the Amazon region, Mâncio Lima, located in the Acre State Brazil. Using Shannon-type light traps installed at 11 collection points near fish ponds, a total of 116 anophelines were collected belonging to nine species...
February 22, 2018: Neotropical Entomology
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