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https://www.readbyqxmd.com/read/27906940/a-new-technique-for-the-treatment-of-lumbar-facet-joint-syndrome-using-intra-articular-injection-with-autologous-platelet-rich-plasma
#1
Jiuping Wu, Zhenwu Du, Yang Lv, Jun Zhang, Wei Xiong, Ruiqiang Wang, Rui Liu, Guizhen Zhang, Qinyi Liu
BACKGROUND AND OBJECTIVES: Lumbar facet joint syndrome is currently suggested to be a main source of axial low back pain, and a large portion of axial low back pain is caused by disorders in lumbar facet joints. Intra-articular injection is one of the most common treatment methods in the early clinical application. Therefore, we attempt to seek a new injectable material, autologous platelet rich plasma (PRP), to treat lumbar facet syndrome, as well as to assess its therapeutic effectiveness and safety...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27891243/a-comprehensive-musculoskeletal-and-peripheral-nervous-system-assessment-of-war-related-bilateral-upper-extremity-amputees
#2
Mostafa Allami, Batool Mousavi, Mehdi Masoumi, Ehsan Modirian, Hadi Shojaei, Fatemeh Mirsalimi, Maryam Hosseini, Pirouz Pirouzi
BACKGROUND: Upper limb amputations are one of the unpleasant war injuries that armed forces are exposed to frequently. The present study aimed to assess the musculoskeletal and peripheral nervous systems in Iraq-Iran war veterans with bilateral upper extremity amputation. METHODS: The study consisted of taking a history and clinical examinations including demographic data, presence and location of pain, level of amputation, passive and active ranges of movement of the joints across the upper and lower extremities and spine, manual palpation, neurological examination, blood circulation pulses and issues related to a prosthetic limb...
2016: Military Medical Research
https://www.readbyqxmd.com/read/27885810/value-of-18-f-fdg-pet-mri-for-the-outcome-of-ct-guided-facet-block-therapy-in-cervical-facet-syndrome-initial-results
#3
Lino M Sawicki, Benedikt M Schaarschmidt, Philipp Heusch, Christian Buchbender, Sandra Rosenbaum-Krumme, Lale Umutlu, Sven O Eicker, Andreas Bockisch, Gerald Antoch, Frank W Floeth
INTRODUCTION: The aim of this study was to evaluate the ability of (18) F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ((18) F-FDG PET/MRI) to detect PET-positive cervical facet arthropathy and identify patients who benefit from facet block therapy. METHODS: Ten patients with cervical facet syndrome (mean age: 65 ± 12 years) underwent (18) F-FDG PET/MRI of the neck. Focal (18) F-FDG uptake in PET-positive facet joints served as target for computed tomography (CT)-guided facet blocks...
November 25, 2016: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/27859883/atomic-force-microscopy-and-lamins-a-review-study-towards-future-combined-investigations
#4
REVIEW
Ilaria Pecorari, Luca Puzzi, Orfeo Sbaizero
In the last decades, atomic force microscopy (AFM) underwent a rapid and stunning development, especially for studying mechanical properties of biological samples. The numerous discoveries relying to this approach, have increased the credit of AFM as a versatile tool, and potentially eligible as a diagnostic equipment. Meanwhile, it has become strikingly evident that lamins are involved on the onset and development of certain diseases, including cancer, Hutchinson-Gilford progeria syndrome, cardiovascular pathologies, and muscular dystrophy...
November 17, 2016: Microscopy Research and Technique
https://www.readbyqxmd.com/read/27822303/emotional-dysregulation-and-trauma-predicting-psychopathy-dimensions-in-female-and-male-juvenile-offenders
#5
Kathrin Sevecke, Sebastian Franke, David Kosson, Maya Krischer
BACKGROUND: Psychopathy is a specific syndrome that predicts future violent and aggressive behavior in adults. Studies in youth and adults have demonstrated a strong association between early traumatic incidents and later dissocial behavior. Moreover, the impact of personality pathology and emotional dysregulation on aggressive and violent behavior is well established. However, few studies have addressed the relationship between early traumatization and psychopathic traits in adolescents...
2016: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/27816039/internet-addiction-and-its-facets-the-role-of-genetics-and-the-relation-to-self-directedness
#6
Elisabeth Hahn, Martin Reuter, Frank M Spinath, Christian Montag
A growing body of research focuses on problematic behavior patterns related to the use of the Internet to identify contextual as well as individual risk factors of this new phenomenon called Internet addiction (IA). IA can be described as a multidimensional syndrome comprising aspects such as craving, development of tolerance, loss of control and negative consequences. Given that previous research on other addictive behaviors showed substantial heritability, it can be expected that the vulnerability to IA may also be due to a person's genetic predisposition...
October 24, 2016: Addictive Behaviors
https://www.readbyqxmd.com/read/27802178/impostor-syndrome-and-burnout-among-american-medical-students-a-pilot-study
#7
Jennifer A Villwock, Lindsay B Sobin, Lindsey A Koester, Tucker M Harris
Objectives: To describe levels of burnout and impostor syndrome (IS) in medical students, and to recognize demographic differences in those experiencing burnout and IS. Methods: Research participants included 2,612 medical students who entered Jefferson Medical College between 2002 and 2012. This sample was divided into two groups: Matriculants between 2002 and 2007 (n=1,380) and between 2008 and 2012 (n=1,232). Data for 2002-2007 matriculants were subjected to EFA (principal component factor extraction), and data for matriculants of 2008-2012 were used for CFA (structural equation modeling, and root mean square error for approximation)...
October 31, 2016: International Journal of Medical Education
https://www.readbyqxmd.com/read/27792054/evaluation-and-treatment-of-lumbar-facet-cysts
#8
Barrett S Boody, Jason W Savage
Lumbar facet cysts are a rare but increasingly common cause of symptomatic nerve root compression and can lead to radiculopathy, neurogenic claudication, and cauda equina syndrome. The cysts arise from the zygapophyseal joints of the lumbar spine and commonly demonstrate synovial herniation with mucinous degeneration of the facet joint capsule. Lumbar facet cysts are most common at the L4-L5 level and often are associated with spondylosis and degenerative spondylolisthesis. Advanced imaging studies have increased diagnosis of the cysts; however, optimal treatment of the cysts remains controversial...
December 2016: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/27744135/classification-characteristics-of-a-chronic-low-back-pain-population-using-a-combined-mckenzie-and-patho-anatomical-assessment
#9
Carol Ann Flavell, Susan Gordon, Laurence Marshman
BACKGROUND: Physiotherapists use musculo-skeletal classification systems for patient assessment. Since its early development, the McKenzie lumbar spine assessment (MK) has been incorporated into examination algorithms and combined with a series of patho-anatomical diagnostic tests. No previous studies have used a MK and a combined examination (MK-C) to provide a detailed profile of patients, report and compare the classification characteristics of a chronic low back pain (CLBP) population...
December 2016: Manual Therapy
https://www.readbyqxmd.com/read/27719837/assessment-of-patients-with-functional-neurologic-disorders
#10
A Carson, M Hallett, J Stone
We describe an overall approach and structure to the clinical assessment of the patient with a functional neurologic disorder. Whilst the primary purpose of the assessment is to make a diagnosis and develop a treatment plan, we believe the assessment also plays a key role in treatment in its own right, as it sets a tone and context for future clinical interactions. We aim to set up an atmosphere of collaboration based on taking the patient's problems seriously, and emphasizing that all facets of the patient's presentation - physical, psychologic, and social - are of importance...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27710242/metabolic-fingerprints-of-circulating-igf-i-and-the-igf-i-igfbp-3-ratio-a-multi-fluid-metabolomics-study
#11
Henrike Knacke, Maik Pietzner, Kieu Trinh Do, Werner Römisch-Margl, Gabi Kastenmüller, Uwe Völker, Henry Völzke, Jan Krumsiek, Anna Artati, Henri Wallaschofski, Matthias Nauck, Karsten Suhre, Jerzy Adamski, Nele Friedrich
OBJECTIVE: Insulin-like Growth Factor (IGF-I) is known for its various physiological and severe pathophysiological effects on human metabolism, however underlying molecular mechanisms still remain unsolved. To reveal possible molecular mechanisms mediating these effects, for the first time we associated serum IGF-I levels with multi-fluid untargeted metabolomics data. METHODS: Plasma/urine samples of 995 non-diabetic participants of the Study of Health in Pomerania (SHIP-TREND) were characterized by mass spectrometry...
October 6, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27706118/cervical-facet-joint-syndrome-a-possible-cause-of-chronic-cervicobrachial-pain
#12
Emanuele Piraccini, Helen Byrne, Stefano Maitan
No abstract text is available yet for this article.
October 5, 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/27625236/an-algorithmic-approach-for-clinical-management-of-low-back-pain
#13
V V Ramesh Chandra, B C M Prasad, C Krishna Mohan, T C Kalawat, V Satyanarayana, A Y Lakshmi
BACKGROUND: Low back pain is caused by a variety of conditions. When conventional imaging failed, single-photon emission computed tomography (SPECT) was superior to scintigraphy in identifying the pathology. Injection therapies are often helpful in treating the pathology. AIM: To determine the cause of chronic low backache in individuals with normal conventional imaging (radiographs, computed tomography and magnetic resonance imaging), to determine the specific pathology using scintigraphic studies and diagnostic blocks; and, to treat the individuals with various spinal injection techniques and determine their efficacy...
September 2016: Neurology India
https://www.readbyqxmd.com/read/27623609/how-do-adults-with-down-syndrome-perceive-physical-activity
#14
Adam Love, Stamatis Agiovlasitis
Adults with Down syndrome (DS) tend to have low physical activity levels, which may relate to how they perceive participation in physical activities. The current study entailed interviews with 30 adults with DS (age 18-71 yr, 18 women) to examine how they perceived physical activity, exercise, and sport. Through qualitative analysis informed by grounded theory, the investigators found that adults with DS have positive perceptions of physical activity that center on enjoyment. Three facets of enjoyment were identified: interaction, achievement, and process...
July 2016: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/27618781/percutaneous-radiofrequency-facet-capsule-denervation-as-an-alternative-target-in-lumbar-facet-syndrome
#15
Wael Mohamed Mohamed Moussa, Wael Khedr
OBJECTIVES: Percutaneous radiofrequency denervation of the medial dorsal branch is often used in chronic low back pain of intervertebral facet etiology, which is sometimes difficult to perform and recurrence of pain often ensues. We theorized that shifting the target of RF coagulation to the facet joint capsule would provide an easier target and a longer-lived pain relieving response. PATIENTS AND METHODS: A prospective randomized controlled trial where 120 patients diagnosed with CLBP of a confirmed facet origin were randomly divided into three equal groups, the first was submitted to percutaneous radiofrequency coagulation of the facet joint capsule, the second underwent percuataneous denervation of the medial dorsal branch and the third did not receive radiofrequency lesioning...
November 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27596569/smartphone-based-early-cardiac-rehabilitation-in-patients-with-acute-coronary-syndromes-smart-rehab-trial-a-randomized-controlled-trial-protocol
#16
Matias B Yudi, David J Clark, David Tsang, Michael Jelinek, Katie Kalten, Subodh Joshi, Khoa Phan, Arthur Nasis, John Amerena, Sandeep Arunothayaraj, Chris Reid, Omar Farouque
BACKGROUND: There are well-documented treatment gaps in secondary prevention of coronary heart disease and no clear guidelines to assist early physical activity after acute coronary syndromes (ACS). Smartphone technology may provide an innovative platform to close these gaps. This paper describes the study design of a randomized controlled trial assessing whether a smartphone-based secondary prevention program can facilitate early physical activity and improve cardiovascular health in patients with ACS...
September 5, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27529667/burnout-and-depression-label-related-stigma-help-seeking-and-syndrome-overlap
#17
Renzo Bianchi, Jay Verkuilen, Romain Brisson, Irvin Sam Schonfeld, Eric Laurent
We investigated whether burnout and depression differed in terms of public stigma and help-seeking attitudes and behaviors. Secondarily, we examined the overlap of burnout and depressive symptoms. A total of 1046 French schoolteachers responded to an Internet survey in November-December 2015. The survey included measures of public stigma, help-seeking attitudes and behaviors, burnout and depressive symptoms, self-rated health, neuroticism, extraversion, history of anxiety or depressive disorder, social desirability, and socio-demographic variables...
November 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27504982/accessory-anterolateral-talar-facet-in-populations-with-and-without-symptoms-prevalence-and-relevant-associated-ankle-mri-findings
#18
Üstün Aydıngöz, Osman Melih Topcuoğlu, Aysegül Görmez, Tijen Cankurtaran, Elif Dilara Topcuoğlu, Fatma Bilge Ergen
OBJECTIVE: The purpose of this study was to determine the prevalence of and relevant findings associated with the accessory anterolateral talar facet, which may have a role in talocalcaneal impingement and sinus tarsi syndrome, on ankle MR images of persons with and those without symptoms. SUBJECTS AND METHODS: In this case-control study, three observers independently reviewed 1.5-T or 3-T MR images of 110 ankles with symptoms in 100 consecutively registered patients (age range, 16-79 years; mean, 41...
August 9, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27500823/nephrotoxin-microinjection-in-zebrafish-to-model-acute-kidney-injury
#19
Robert A McKee, Rebecca A Wingert
The kidneys are susceptible to harm from exposure to chemicals they filter from the bloodstream. This can lead to organ injury associated with a rapid decline in renal function and development of the clinical syndrome known as acute kidney injury (AKI). Pharmacological agents used to treat medical circumstances ranging from bacterial infection to cancer, when administered individually or in combination with other drugs, can initiate AKI. Zebrafish are a useful animal model to study the chemical effects on renal function in vivo, as they form an embryonic kidney comprised of nephron functional units that are conserved with higher vertebrates, including humans...
July 17, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27490019/rationally-designed-cenp-mnmos4-core-shell-nanoparticles-for-modulating-multiple-facets-of-alzheimer-s-disease
#20
Yijia Guan, Nan Gao, Jinsong Ren, Xiaogang Qu
Alzheimer's disease (AD) is a complicated multifactorial syndrome. Lessons have been learned through failed clinical trials that targeting multiple key pathways of the AD pathogenesis is necessary to halt the disease progression. Here, we construct core-shell nanoparticles (CeNP@MnMoS4 ) targeting multiple key pathways of the AD pathogenesis, including elimination of toxic metal ions, decrease of oxidative stress, and promotion of neurite outgrowth. The SOD activity and copper removal capacity of CeNP@MnMoS4 -n (n represents the number of layers of MnMoS4 , n=1-5) was investigated in vitro...
October 4, 2016: Chemistry: a European Journal
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