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https://www.readbyqxmd.com/read/28228331/-efficacy-and-safety-of-available-therapies-in-the-management-of-idiopathic-overactive-bladder-a-systematic-review-of-the-literature
#1
J Moyson, F Legrand, M Vanden Bossche, T Quackels, T Roumeguère
OBJECTIVE: Study the efficacy and adverse events of different pharmacological lines in the treatment of idiopathic overactive bladder (iOAB). METHODS: PubMed research on meta-analyses and randomized controlled trials (RCT) focused on the efficacy and adverse effects of anticholinergics, botulinum toxin and mirabegron since 2005. RESULTS: Ten meta-analyses of anticholinergics were selected; 16 randomized controlled trials (ERC) comparing botulinum toxin A to either anticholinergic or placebo and 10 ERC studying mirabegron...
February 19, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28209730/role-of-stard4-in-sterol-transport-between-the-endocytic-recycling-compartment-and-the-plasma-membrane
#2
David B Iaea, Shu Mao, Frederik W Lund, Frederick R Maxfield
Cholesterol is an essential constituent of membranes in mammalian cells. The plasma membrane and the endocytic recycling compartment (ERC) are both highly enriched in cholesterol. The abundance and distribution of cholesterol among organelles are tightly controlled by a combination of mechanisms involving vesicular and non-vesicular sterol transport processes. Using the fluorescent cholesterol analog, dehydroergosterol, we examined sterol transport between the plasma membrane and the ERC using fluorescence recovery after photobleaching and a novel sterol efflux assay...
February 16, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28191318/structured-pharmaceutical-care-improves-the-health-related-quality-of-life-of-patients-with-asthma
#3
Philip O Anum, Berko P Anto, Audrey G Forson
BACKGROUND: Asthma as a chronic health condition can be controlled when in addition to clinical care, adequate education and support is provided to enhance self-management. Like many other chronic health conditions improved self-management positively impacts the health-related quality of life (HRQoL). It can therefore be said that a well-structured pharmaceutical care delivery that addresses the issues related to patient education and support towards self-management stands a good chance of positively impacting asthma control...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28151394/a-fast-track-anaemia-clinic-in-the-emergency-department-cost-analysis-of-intravenous-iron-administration-for-treating-iron-deficiency-anaemia
#4
Manuel Quintana-Díaz, Raúl Muñoz-Romo, Susana Gómez-Ramírez, José Pavía, Alberto M Borobia, José A García-Erce, Manuel Muñoz
BACKGROUND: A fast-track anaemia clinic (FTAC) for the management of moderate-to-severe iron-deficiency anaemia (IDA) was established in our Emergency Department in 2010. In this FTAC, the replacement of packed red cell transfusion by ferric carboxymaltose administration was proven to be safe and effective. The aim of this study was a cost-analysis of IDA management in the FTAC, comparing this management with the previous standard care pathway consisting of packed red cell transfusion, if needed, and referral to outpatient specialised care...
January 24, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28150278/the-quality-of-a-newly-developed-infant-chest-compression-method-applied-by-paramedics-a-randomized-crossover-manikin-trial
#5
Jacek Smereka, Mariusz Kasinski, Adam Smereka, Jerzy Robert Ładny, Łukasz Szarpak
BACKGROUND: The etiology of sudden cardiac arrest in infants is different from that in adults, with respiratory failure, sudden infant death syndrome, and drowning being the primary causes in the former. According to the European Resuscitation Council (ERC) and American Heart Association (AHA) recommendations, the quality of chest compressions (CC) is a key element affecting the effectiveness of cardiopulmonary resuscitation (CPR). The current ERC and AHA guidelines recommend the 'two-finger technique' (TFT) or 'two-thumb encircling hands technique' (TTHT) for external CCs during infant CPR...
February 2, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28119450/ectopic-expression-of-mouse-melanopsin-in-drosophila-photoreceptors-reveals-fast-response-kinetics-and-persistent-dark-excitation
#6
Bushra Yasin, Elkana Kohn, Maximilian Peters, Rachel Zaguri, Shirley Weiss, Krystina Schopf, Ben Katz, Armin Huber, Baruch Minke
The intrinsically photosensitive retinal ganglion cells (ipRGC) initiate non-image forming light-dependent activities and express the melanopsin (OPN4) photopigment. Several features of ipRGC photosensitivity are characteristic of fly photoreceptors. However, the light-response kinetics of ipRGC is much slower due to unknown reasons. Here we used transgenic Drosophila, in which the mouse OPN4 replaced the native Rh1 photopigment of Drosophila R1-6 photoreceptors, resulting in deformed rhabdomeric structure...
January 24, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28107474/enacted-reading-comprehension-using-bodily-movement-to-aid-the-comprehension-of-abstract-text-content
#7
Michael P Kaschak, Carol M Connor, Jennifer L Dombek
We report a design study that assessed the feasibility of Enacted Reading Comprehension (ERC), an intervention designed to teach 3rd and 4th grade students (n = 40 and 25, respectively) to use gestures to understand an increasingly abstract set of texts. Students were taught to use gestures to understand the idea of "opposing forces" in a concrete setting-the forces at play as tectonic plates move past each other-and then taught to use the gestures to understand opposing forces in more abstract situations. For example, students were taught to use gestures to understand the opposing sides of an argument, and to understand the internal conflicts that arise as individuals are faced with moral dilemmas...
2017: PloS One
https://www.readbyqxmd.com/read/28086796/prophylaxis-of-post-erc-infectious-complications-in-patients-with-biliary-obstruction-by-adding-antimicrobial-agents-into-erc-contrast-media-a-single-center-retrospective-study
#8
Hella Wobser, Agnetha Gunesch, Frank Klebl
BACKGROUND: Patients with biliary obstruction are at high risk to develop septic complications after endoscopic retrograde cholangiography (ERC). We evaluated the benefits of local application of antimicrobial agents into ERC contrast media in preventing post-ERC infectious complications in a high-risk study population. METHODS: Patients undergoing ERC at our tertiary referral center were retrospectively included. Addition of vancomycin, gentamicin and fluconazol into ERC contrast media was evaluated in a case-control design...
January 13, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28054123/-clamshell-thoracotomy-after-thoracic-knife-wounds
#9
Marcus Rudolph, Niko R E Schneider, Erik Popp
Resuscitation in the event of traumatic cardiac arrest was for a long time considered to be a less than promising technique to employ; however, current data indicate that the prospects of success need not be any poorer than for resuscitation due to cardiac distress. The targeted and rapid remedying of reversible causes can re-establish the circulatory function and the European Resuscitation Council (ERC) algorithm for traumatic cardiac arrest is a helpful guide in this respect. This case report illustrates the resolute implementation of this algorithm in the prehospital environment in the case of an attempted suicide by a thoracic knife wound...
January 4, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28019036/utility-of-newly-developed-short-type-double-balloon-endoscopy-for-endoscopic-retrograde-cholangiography-in-postoperative-patients
#10
Masaaki Shimatani, Mitsuo Tokuhara, Kota Kato, Sachi Miyamoto, Masataka Masuda, Masayuki Sakao, Norimasa Fukata, Hideaki Miyoshi, Tsukasa Ikeura, Makoto Takaoka, Kazuichi Okazaki
BACKGROUND AND AIMS: The utility of conventional short-type DBE (C-short DBE) for pancreatobiliary disease in patients with postoperative anatomy had been widely acknowledged and accepted. However, some technical difficulties yet remained. In an attempt to solve these problems, the new short-type DBE (N-short DBE) was uniquely designed for therapeutic endoscopic retrograde cholangiography (ERC) in postoperative patients. The aim of this study was to evaluate the usefulness of N-short DBE for ERC in postoperative patients...
December 26, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28017971/labour-and-childbirth-after-previous-caesarean-section-recommendations-of-the-austrian-society-of-obstetrics-and-gynaecology-oeggg
#11
P Reif, C Brezinka, T Fischer, P Husslein, U Lang, A Ramoni, H Zeisler, P Klaritsch
The new expert recommendation from the Austrian Society of Obstetrics and Gynaecology (OEGGG) comprises an interpretation and summary of guidelines from the leading specialist organisations worldwide (RCOG, ACOG, SOGC, CNGOF, WHO, NIH, NICE, UpToDate). In essence it outlines alternatives to the direct pathway to elective repeat caesarean section (ERCS). In so doing it aligns with international trends, according to which a differentiated, individualised clinical approach is recommended that considers benefits and risks to both mother and child, provides detailed counselling and takes the patient's wishes into account...
December 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/27995852/does-endorectal-coil-mri-increase-the-accuracy-of-preoperative-prostate-cancer-staging
#12
Aydin Pooli, Sudhir Isharwal, Gates Cook, Jennifer M Oliveto, Chad A LaGrange
INTRODUCTION: We sought to investigate the association of preprostatectomy magnetic resonance imaging (MRI) and surgical pathologic findings in patients with prostate cancer. MATERIALS AND METHODS: All patients with prostate cancer and preprostatectomy MRI available between 2002 and 2015 were included. Age, prostate-specific antigen at diagnosis, Gleason score at biopsy, MRI technique, radiology report suggestive of prostate cancer, extraprostatic invasion and seminal vesicle involvement, lymphadenopathy and final pathology report were retrospectively reviewed...
December 2016: Canadian Journal of Urology
https://www.readbyqxmd.com/read/27914590/need-for-multidisciplinary-massive-transfusion-protocol-for-non-trauma-patient
#13
M Quintana-Díaz, J A García Erce
No abstract text is available yet for this article.
December 2016: Medicina Intensiva
https://www.readbyqxmd.com/read/27908204/clinical-implications-of-serial-versus-isolated-biliary-fluorescence-in-situ-hybridization-fish-polysomy-in-primary-sclerosing-cholangitis
#14
Kevin P Quinn, James H Tabibian, Keith D Lindor
BACKGROUND: Cholangiocarcinoma (CCA) is a leading cause of death in patients with primary sclerosing cholangitis (PSC). Biliary polysomy detected by fluorescence in situ hybridization (FISH) helps to identify patients with early CCA, but not all PSC patients with polysomy develop CCA. Here, we examined the features and clinical outcomes of PSC patients with serial versus isolated polysomy. METHODS: All patients with PSC who underwent ≥1 endoscopic retrograde cholangiography (ERC) with FISH testing at Mayo Clinic, Rochester from 2008-2011 were identified...
April 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27865608/benefit-in-long-term-response-and-mortality-of-treatment-with-intravenous-immunoglobulin-prior-to-plasmapheresis-in-peripheral-polyneuropathies
#15
I Parra-Salinas, V P González-Rodríguez, J A Gracia Pina, J J Gimeno Lozano, J A García-Erce
OBJECTIVES: The benefits of plasmapheresis (PA) for neurologic autoimmune diseases have been widely demonstrated. Little is known about the long-term neurologic prognosis and course after PA and immunosuppressive (IS) and/or intravenous immunoglobulin (IVIG) treatment. We aimed to analyse features associated with short-term response and long-term outcome and prognosis (neurologic status and mortality) of peripheral polyneuropathy (PP) and central nervous system acute inflammatory disease (CNSAID) treated with PA...
February 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/27861697/practice-variation-of-vaginal-birth-after-cesarean-and-the-influence-of-risk-factors-at-patient-level-a-retrospective-cohort-study
#16
MULTICENTER STUDY
Emy Vankan, Ellen N Schoorel, Sander M van Kuijk, Ben-Willem J Mol, Jan G Nijhuis, Robert Aardenburg, Marleen Alink, Karin de Boer, Friso M C Delemarre, Carmen D Dirksen, Ivo M van Dooren, Maureen T M Franssen, Mesrure Kaplan, Gunilla Kleiverda, Simone M I Kuppens, Anneke Kwee, Josje Langenveld, Frans T Lim, Sonja Melman, Marko J Sikkema, Luc J Smits, Harry Visser, Mallory Woiski, Hubertina C Scheepers, Rosella P Hermens
INTRODUCTION: Large practice variation exists in mode of delivery after cesarean section, suggesting variation in implementation of contemporary guidelines. We aim to evaluate this practice variation and to what extent this can be explained by risk factors at patient level. MATERIAL AND METHODS: This retrospective cohort study was performed among 17 Dutch hospitals in 2010. Women with one prior cesarean section without a contraindication for a trial of labor were included...
February 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27859925/material-specificity-drives-medial-temporal-lobe-familiarity-but-not-hippocampal-recollection
#17
Alex Kafkas, Ellen M Migo, Robin G Morris, Michael D Kopelman, Daniela Montaldi, Andrew R Mayes
The specific role of the perirhinal (PRC), entorhinal (ERC) and parahippocampal cortices (PHC) in supporting familiarity-based recognition remains unknown. An fMRI study explored whether these medial temporal lobe (MTL) structures responded in the same way or differentially to familiarity as a function of stimulus type at recognition. A secondary aim was to explore whether the hippocampus responds in the same way to equally strong familiarity and recollection and whether this is influenced by the kind of stimulus involved...
February 2017: Hippocampus
https://www.readbyqxmd.com/read/27806633/surveillance-of-primary-sclerosing-cholangitis-with-erc-and-brush-cytology-risk-factors-for-cholangiocarcinoma
#18
Sonja Boyd, Harri Mustonen, Andrea Tenca, Kalle Jokelainen, Johanna Arola, Martti A Färkkilä
OBJECTIVE: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease leading to bile duct strictures and fibrosis, and predisposing to cholangiocarcinoma (CCA). Biliary dysplasia is a known precursor of CCA. In our unit, PSC patients undergo regular surveillance with ERC and brush cytology (BC), and liver transplantation is an option in case with biliary dysplasia. We evaluated the risk factors for biliary dysplasia and CCA based on ERC imaging, BC and liver function tests...
February 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27798373/prolongation-of-cardiac-allograft-survival-by-endometrial-regenerative-cells-focusing-on-b-cell-responses
#19
Xiaoxi Xu, Xiaochun Li, Xiangying Gu, Bai Zhang, Weijun Tian, Hongqiu Han, Peng Sun, Caigan Du, Hao Wang
: : Endometrial regenerative cells (ERCs) have been recently evaluated as an attractive candidate source for emerging stem cell therapies in immunosuppression, but their role in immunoregulation is not fully understood. The present study was designed to investigate their effects, especially on B-cell responses in heart transplantation. In this study, ERCs were noninvasively obtained from menstrual blood. Heart transplantation was performed between C57BL/6 (H-2(b)) donor mice and BALB/c (H-2(d)) recipients...
October 26, 2016: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/27796141/ultrathin-choledochoscope-improves-outcomes-in-the-treatment-of-gallstones-and-suspected-choledocholithiasis
#20
Hong-Tian Xia, Bin Liang, Yang Liu, Tao Yang, Jian-Ping Zeng, Jia-Hong Dong
BACKGROUND: We aimed to compare laparoscopic cholecystectomy (LC) and simultaneous laparoscopic transcystic common bile duct exploration (LTCBDE) using an ultrathin choledochoscope with LC followed by endoscopic retrograde cholangiopancreatography (ERC) and endoscopic sphincterotomy (ES) when indicated. METHODS: We retrospectively reviewed the records of patients seen between 2004 and 2014 and treated with LC+LTCBDE or LC for gallstones and suspected choledocholithiasis...
December 2016: Expert Review of Gastroenterology & Hepatology
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