Giovanni Luigi De Maria, John P Greenwood, Azfar G Zaman, Didier Carrié, Pierre Coste, Marco Valgimigli, Miles Behan, Colin Berry, Andrejs Erglis, Vasileios F Panoulas, Eric Van Belle, Christian Juhl Terkelsen, Lukas Hunziker Munsch, Ajay K Jain, Jens Flensted Lassen, Nick Palmer, Gregg W Stone, Adrian P Banning
BACKGROUND: Primary percutaneous coronary intervention (pPCI) has improved clinical outcomes in patients with ST-segment-elevation myocardial infarction. However, as many as 50% of patients still have suboptimal myocardial reperfusion and experience extensive myocardial necrosis. The PiCSO-AMI-I trial (Pressure-Controlled Intermittent Coronary Sinus Occlusion-Acute Myocardial Infarction-I) evaluated whether PiCSO therapy can further reduce myocardial infarct size (IS) in patients undergoing pPCI...
April 2024: Circulation. Cardiovascular Interventions