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https://www.readbyqxmd.com/read/29054119/pollinator-independent-orchid-attracts-biotic-pollinators-due-the-production-of-lipoidal-substances
#1
E R Pansarin, P J Bergamo, M J Ferreira-Caliman
● Flowering plants often depend on the attraction of biotic pollinators for sexual reproduction. Consequently, the emergence and maintenance of selected floral attributes related to pollinator attraction and rewarding are driven by pollinators pressures. ● In this paper we explore the effect of pollinators, rainfall, and temperature and air humidity on the reproduction of a Brazilian terrestrial orchid, Cranichis candida based on data of phenology, flower resources, olfactory and visual attraction cues, pollinators and breeding system...
October 20, 2017: Plant Biology
https://www.readbyqxmd.com/read/29054101/virtual-simulated-care-coordination-rounds-for-nursing-students
#2
Donna M Badowski
Implementation of the Affordable Care Act has nursing education reflecting on paradigm shifts in order to prepare nursing students for the evolving health care environment. The traditional focus of nursing education on nursing care in acute care settings does not provide learning experiences in care coordination and transitional care management skills. Virtual simulated care coordination rounds, using the National League for Nursing Advancing Care Excellence resources, offer nursing students an innovative experience in care coordination and transition care management...
November 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29054036/snava-a-real-time-multi-fpga-multi-model-spiking-neural-network-simulation-architecture
#3
Athul Sripad, Giovanny Sanchez, Mireya Zapata, Vito Pirrone, Taho Dorta, Salvatore Cambria, Albert Marti, Karthikeyan Krishnamourthy, Jordi Madrenas
Spiking Neural Networks (SNN) for Versatile Applications (SNAVA) simulation platform is a scalable and programmable parallel architecture that supports real-time, large-scale, multi-model SNN computation. This parallel architecture is implemented in modern Field-Programmable Gate Arrays (FPGAs) devices to provide high performance execution and flexibility to support large-scale SNN models. Flexibility is defined in terms of programmability, which allows easy synapse and neuron implementation. This has been achieved by using a special-purpose Processing Elements (PEs) for computing SNNs, and analyzing and customizing the instruction set according to the processing needs to achieve maximum performance with minimum resources...
October 5, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29053960/a-general-strategy-for-discovery-of-inhibitors-and-activators-of-ring-and-u-box-e3-ligases-with-ubiquitin-variants
#4
Mads Gabrielsen, Lori Buetow, Mark A Nakasone, Syed Feroj Ahmed, Gary J Sibbet, Brian O Smith, Wei Zhang, Sachdev S Sidhu, Danny T Huang
RING and U-box E3 ubiquitin ligases regulate diverse eukaryotic processes and have been implicated in numerous diseases, but targeting these enzymes remains a major challenge. We report the development of three ubiquitin variants (UbVs), each binding selectively to the RING or U-box domain of a distinct E3 ligase: monomeric UBE4B, phosphorylated active CBL, or dimeric XIAP. Structural and biochemical analyses revealed that UbVs specifically inhibited the activity of UBE4B or phosphorylated CBL by blocking the E2∼Ub binding site...
October 19, 2017: Molecular Cell
https://www.readbyqxmd.com/read/29053884/looking-into-cognitive-impairment-in-primary-progressive-multiple-sclerosis
#5
Maria Petracca, James Sumowski, Michelle Fabian, Aaron Miller, Fred Lublin, Matilde Inglese
BACKGROUND: Cognitive impairment in primary-progressive multiple sclerosis (PP-MS) is correlated with global brain atrophy. Unfortunately, brain volumes computation requires processing resources not widely available in clinical practice. Therefore we decided to test the predictive role of retinal atrophy metrics on cognitive decline, applying them as proxy of grey matter (GM) atrophy in PP-MS. METHODS: Twenty-five PP-MS patients completed the Brief International Cognitive Assessment for MS (BICAMS) and underwent spectral-domain OCT and 3...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29053852/genome-wide-scan-and-analysis-of-positive-selective-signatures-in-dwarf-brown-egg-layers-and-silky-fowl-chickens
#6
Mengmeng Zhang, Liu Yang, Zhencheng Su, Muzhen Zhu, Wenting Li, Keliang Wu, Xuemei Deng
Chinese domestic chickens have been routinely subjected to artificial selection for the production of meats and eggs. Selection results in distinctive signatures in the genome that can reveal the genes underlying phenotypes of interest to breeders. In this study, we used the Chicken60K SNP chip to analyze DNA from Dwarf Brown-egg Layers (DB, n = 203) and Silky Fowls (SF, n = 181) and then examined the relative extended haplotype homozygosity (REHH) and fixation index (FST) to detect selection signatures. Since population structure analysis showed that SF was stratified into 2 subpopulations (SF1 and SF2), we removed the 20 SF1 chickens, and the remaining individuals (DB and SF2) were scanned for genome-wide selection signatures...
October 5, 2017: Poultry Science
https://www.readbyqxmd.com/read/29053822/characterization-of-indigenous-chicken-production-systems-in-rwanda
#7
J Mahoro, T K Muasya, F Mbuza, R Habimana, A K Kahi
Characterization of indigenous chicken (IC) production systems in Rwanda was conducted from November 2015 to January 2016 with the aim of understanding socio-economic characteristics, management of IC, production parameters, feed resources, and constraints faced by farmers rearing IC. A survey involving 206 households was carried out in 5 districts with the highest populations of IC using structured questionnaires. Data were analyzed using SAS software. The results showed that the majority of respondents (62...
September 14, 2017: Poultry Science
https://www.readbyqxmd.com/read/29053730/assessment-of-intra-and-interregional-genetic-variation-in-the-eastern-red-backed-salamander-plethodon-cinereus-via-analysis-of-novel-microsatellite-markers
#8
Alexander C Cameron, Jeffry J Anderson, Robert B Page
The red-backed salamander (Plethodon cinereus) has long-served as a model system in ecology, evolution, and behavior, and studies surveying molecular variation in this species have become increasingly common over the past decade. However, difficulties are commonly encountered when extending microsatellite markers to populations that are unstudied from a genetic perspective due to high levels of genetic differentiation across this species' range. To ameliorate this issue, we used 454 pyrosequencing to identify hundreds of microsatellite loci...
2017: PloS One
https://www.readbyqxmd.com/read/29053711/evaluation-of-spoligotyping-snps-and-customised-miru-vntr-combination-for-genotyping-mycobacterium-tuberculosis-clinical-isolates-in-madagascar
#9
Rondroarivelo Rasoahanitralisoa, Niaina Rakotosamimanana, David Stucki, Christophe Sola, Sebastien Gagneux, Voahangy Rasolofo Razanamparany
BACKGROUND: Combining different molecular typing methods for Mycobacterium tuberculosis complex (MTBC) can be a powerful tool for molecular epidemiology-based investigation of TB. However, the current standard method that provides high discriminatory power for such a combination, mycobacterial interspersed repetitive units-variable numbers of tandem repeats typing (MIRU-VNTR), is laborious, time-consuming and often too costly for many resource-limited laboratories. We aimed to evaluate a reduced set of loci for MIRU-VNTR typing in combination with spoligotyping and SNP-typing for routine molecular epidemiology of TB...
2017: PloS One
https://www.readbyqxmd.com/read/29053698/simultaneous-multi-surface-anodizations-and-stair-like-reverse-biases-detachment-of-anodic-aluminum-oxides-in-sulfuric-and-oxalic-acid-electrolyte
#10
Healin Im, Seok Hwan Jeong, Dong Hyuk Park, Sunkook Kim, Young Ki Hong
After reporting on the two-step anodization, nanoporous anodic aluminum oxides (AAOs) have been widely utilized in the versatile fields of fundamental sciences and industrial applications owing to their periodic arrangement of nanopores with relatively high aspect ratio. However, the techniques reported so far, which could be only valid for mono-surface anodization, show critical disadvantages, i.e., time-consuming as well as complicated procedures, requiring toxic chemicals, and wasting valuable natural resources...
October 5, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29053676/laminotomy-for-lumbar-dorsal-root-ganglion-access-and-injection-in-swine
#11
Mark D Unger, Timothy P Maus, Ross C Puffer, Laura K Newman, Bradford L Currier, Andreas S Beutler
Dorsal root ganglia (DRG) are anatomically well defined structures that contain all primary sensory neurons below the head. This fact makes DRG attractive targets for injection of novel therapeutics aimed at treating chronic pain. In small animal models, laminectomy has been used to facilitate DRG injection because it involves surgical removal of the vertebral bone surrounding each DRG. We demonstrate a technique for intraganglionic injection of lumbar DRG in a large animal species, namely, swine. Laminotomy is performed to allow direct access to DRG using standard neurosurgical techniques, instruments, and materials...
October 10, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29053640/enhancing-resources-at-the-workplace-with-health-promoting-leadership
#12
Paul Jiménez, Anita Bregenzer, K Wolfgang Kallus, Bianca Fruhwirth, Verena Wagner-Hartl
Leaders engaging in health-promoting leadership can influence their employees' health directly by showing health awareness or indirectly by changing working conditions. With health-promoting leadership, leaders are able to support a healthy working environment by providing resource-oriented working conditions for their employees to support their health. Changing working conditions in a health-supportive way can prevent possible negative consequences from critical working conditions (e.g., burnout risk). The present study examined the relationship between health-promoting leadership and the employees' resources, stress and burnout...
October 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29053585/companion-plants-for-aphid-pest-management
#13
REVIEW
Refka Ben-Issa, Laurent Gomez, Hélène Gautier
A potential strategy for controlling pests is through the use of "companion plants" within a crop system. This strategy has been used in several trials to fight against a major crop insect pest: the aphid. We reviewed the literature to highlight the major mechanisms by which a companion plant may act. Trials carried out under laboratory or field conditions revealed that companion plants operate through several mechanisms. A companion plant may be associated with a target crop for various reasons. Firstly, it can attract aphids and draw them away from their host plants...
October 20, 2017: Insects
https://www.readbyqxmd.com/read/29053490/paea-accreditation-task-force-briefing-paper-moving-toward-outcomes-based-accreditation
#14
Mary Jo Bondy, Sara Fletcher, Steven Lane
In anticipation of a revision to the Standards for Accreditation, the Phyisician Assistant Education Association (PAEA) charged a small task force to develop a strategy for engaging its members in the revision process. Rather than focusing on the current Standards, the task force members recommend a backward design approach to determine the desired outcomes of a successful revision to the Standards. Ultimately, the group believes that shifting to an outcomes-based model for accreditation will allow for greater innovation in physician assistant education and reduce the strain on programs facing resource limitations, particularly clinical site shortages...
October 19, 2017: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/29053488/causes-of-childhood-vision-impairment-in-the-school-for-the-blind-in-eritrea
#15
Rajendra Gyawali, Vanessa R Moodley
SIGNIFICANCE: Our study provides the much-needed evidence on causes of childhood blindness in Eritrea. This will assist authorities to plan appropriate strategies and implement preventive, curative, and rehabilitative services to address these causes of vision loss in children in this resource-limited country. PURPOSE: This study aims to identify the causes of severe vision impairment and blindness in children attending the only school for the blind in Eritrea. METHODS: All children enrolled in the school were examined, and the World Health Organization form for the examination of visually impaired children was used to record the data...
October 19, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29053453/distributed-continuous-time-algorithms-for-resource-allocation-problems-over-weight-balanced-digraphs
#16
Zhenhua Deng, Shu Liang, Yiguang Hong
In this paper, a distributed resource allocation problem with nonsmooth local cost functions is considered, where the interaction among agents is depicted by strongly connected and weight-balanced digraphs. Here the decision variable of each agent is within a local feasibility constraint described as a convex set, and all the decision variables have to satisfy a network resource constraint, which is the sum of available resources. To solve the problem, a distributed continuous-time algorithm is developed by virtue of differentiated projection operations and differential inclusions, and its convergence to the optimal solution is proved via the set-valued LaSalle invariance principle...
October 17, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/29053359/cannibalism-and-intraguild-predation-community-dynamics-coexistence-competitive-exclusion-and-the-loss-of-alternative-stable-states
#17
Benjamin J Toscano, Vincent Hin, Volker H W Rudolf
Predators often exert strong top-down regulation of prey, but in many systems, juvenile predators must compete with their future prey for a shared resource. In such life-history intraguild predation (LHIGP) systems, prey can therefore also regulate the recruitment and thus population dynamics of their predator via competition. Theory predicts that such stage-structured systems exhibit a wide range of dynamics, including alternative stable states. Here we show that cannibalism is an exceedingly common interaction within natural LHIGP systems that determines what coexistence states are possible...
November 2017: American Naturalist
https://www.readbyqxmd.com/read/29053284/structure-of-the-resource-theory-of-quantum-coherence
#18
Alexander Streltsov, Swapan Rana, Paul Boes, Jens Eisert
Quantum coherence is an essential feature of quantum mechanics which is responsible for the departure between the classical and quantum world. The recently established resource theory of quantum coherence studies possible quantum technological applications of quantum coherence, and limitations that arise if one is lacking the ability to establish superpositions. An important open problem in this context is a simple characterization for incoherent operations, constituted by all possible transformations allowed within the resource theory of coherence...
October 6, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29052934/the-contribution-of-alternative-splicing-to-genetic-risk-for-psychiatric-disorders
#19
REVIEW
Emma Reble, Aidan Dineen, Cathy L Barr
A genetic contribution to psychiatric disorders has clearly been established and genome-wide association studies now provide the location of risk genes and genetic variants associated with risk. However, the mechanism by which these genes and variants contribute to psychiatric disorders is mostly undetermined. This is in part because non-synonymous protein coding changes cannot explain the majority of variants associated with complex genetic traits. Based on this, it is predicted that these variants are causing gene expression changes, including changes to alternative splicing...
October 20, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29052792/prediction-of-binding-poses-to-fxr-using-multi-targeted-docking-combined-with-molecular-dynamics-and-enhanced-sampling
#20
Soumendranath Bhakat, Emil Åberg, Pär Söderhjelm
Advanced molecular docking methods often aim at capturing the flexibility of the protein upon binding to the ligand. In this study, we investigate whether instead a simple rigid docking method can be applied, if combined with multiple target structures to model the backbone flexibility and molecular dynamics simulations to model the sidechain and ligand flexibility. The methods are tested for the binding of 35 ligands to FXR as part of the first stage of the Drug Design Data Resource (D3R) Grand Challenge 2 blind challenge...
October 20, 2017: Journal of Computer-aided Molecular Design
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