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https://www.readbyqxmd.com/read/29791363/design-of-a-portable-phantom-device-to-simulate-tissue-oxygenation-and-blood-perfusion
#1
Xiang Lv, Hongyu Chen, Guangli Liu, Shuwei Shen, Qiang Wu, Chuanzhen Hu, Jialuo Li, Erbao Dong, Ronald X Xu
We propose a portable phantom system for calibration and validation of medical optical devices in a clinical setting. The phantom system comprises a perfusion module and an exchangeable tissue-simulating phantom that simulates tissue oxygenation and blood perfusion. The perfusion module consists of a peristaltic pump, two liquid storage units, and two pressure suppressors. The tissue-simulating phantom is fabricated by a three-dimensional (3D) printing process with microchannels embedded to simulate blood vessels...
May 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29791138/a-three-dimensional-printed-poly-vinyl-alcohol-substrate-with-controlled-on-demand-degradation-for-transient-electronics
#2
Jinsu Yoon, Jungmin Han, Bongsik Choi, Yongwoo Lee, Yeamin Kim, Jinhee Park, Meehyun Lim, Min-Ho Kang, Dae Hwan Kim, Dong Myong Kim, Sungho Kim, Sung-Jin Choi
Electronics that degrade after stable operation for a desired operating time, called transient electrons, are of great interest in many fields, including biomedical implants, secure memory devices, and environmental sensors. Thus, the development of transient materials is critical for the advancement of transient electronics and their applications. However, previous reports have mostly relied on achieving transience in aqueous solutions where the transience time is largely pre-determined based on the materials initially selected at the beginning of fabrication...
May 23, 2018: ACS Nano
https://www.readbyqxmd.com/read/29790875/visible-light-induced-electropolymerization-of-suspended-hydrogel-bioscaffolds-in-a-microfluidic-chip
#3
Pan Li, Haibo Yu, Na Liu, Feifei Wang, Gwo-Bin Lee, Yuechao Wang, Lianqing Liu, Wen Jung Li
The development of microengineered hydrogels co-cultured with cells in vitro could advance in vivo bio-systems in both structural complexity and functional hierarchy, which holds great promise for applications in regenerative tissues or organs, drug discovery and screening, and bio-sensors or bio-actuators. Traditional hydrogel microfabrication technologies such as ultraviolet (UV) laser or multiphoton laser stereolithography and three-dimensional (3D) printing systems have advanced the development of 3D hydrogel micro-structures but need either expensive and complex equipment, or harsh material selection with limited photoinitiators...
May 23, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29789910/a-radiopaque-3d-printed-anthropomorphic-phantom-for-simulation-of-ct-guided-procedures
#4
Paul Jahnke, Felix Benjamin Schwarz, Marco Ziegert, Tobias Almasi, Owais Abdelhadi, Maximilian Nunninger, Bernd Hamm, Michael Scheel
OBJECTIVES: To develop an anthropomorphic phantom closely mimicking patient anatomy and to evaluate the phantom for the simulation of computed tomography (CT)-guided procedures. METHODS: Patient CT images were printed with aqueous potassium iodide solution (1 g/mL) on paper. The printed paper sheets were stacked in alternation with 1-mm thick polyethylene foam layers, cut to the patient shape and glued together to create an anthropomorphic abdomen phantom. Ten interventional radiologists performed periradicular infiltration on the phantom and rated the phantom procedure regarding different aspects of suitability for simulating CT-guided procedures...
May 22, 2018: European Radiology
https://www.readbyqxmd.com/read/29787894/3d-printing-of-drug-loaded-gyroid-lattices-using-selective-laser-sintering
#5
Fabrizio Fina, Alvaro Goyanes, Christine M Madla, Atheer Awad, Sarah J Trenfield, Jia Min Kuek, Pavanesh Patel, Simon Gaisford, Abdul W Basit
Three-dimensional printing (3DP) is gaining momentum in the field of pharmaceuticals, offering innovative opportunities for medicine manufacture. Selective laser sintering (SLS) is a novel, high resolution and single-step printing technology that we have recently introduced to the pharmaceutical sciences. The aim of this work was to use SLS 3DP to fabricate printlets (3D printed tablets) with cylindrical, gyroid lattice and bi-layer structures having customisable release characteristics. Paracetamol-loaded constructs from four different pharmaceutical grade polymers, including polyethylene oxide, Eudragit (L100-55 and RL) and ethyl cellulose, were created using SLS 3DP...
May 19, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29787582/determination-of-red-blood-cell-deformability-using-centrifugal-force-in-a-three-dimensional-printed-mini-disk-3d-pmd
#6
Hyunjung Lim, Seung Min Back, Jeonghun Nam, Hyuk Choi
Measuring red blood cell (RBC) deformability has become important for clinical disease diagnostics. Various methods for measuring RBC deformability have been developed; however, they require costly and large instruments, long measuring time, and skilled personnel. In this study, we present a three-dimensional-printed mini-disk (3D-PMD) for measuring RBC deformability to overcome the previous limitations. For a miniaturized and low-cost setup, the 3D-PMD was fabricated by a 3D printing technique, which had not yet been used for fabricating a lab-on-a-compact disk (LOCD)...
2018: PloS One
https://www.readbyqxmd.com/read/29786607/pre-set-extrusion-bioprinting-for-multiscale-heterogeneous-tissue-structure-fabrication
#7
Donggu Kang, Geunseon Ahn, Donghwan Kim, Hyun-Wook Kang, Seokhwan Yun, Won-Soo Yun, Jin-Hyung Shim, Songwan Jin
Recent advances in three-dimensional (3D) bioprinting technology have led to various attempts in fabricating human tissue-like structures. However, current bioprinting technologies have limitations for creating native tissue-like structures. To resolve these issues, we developed a new pre-set extrusion bioprinting technique that can create heterogeneous, multicellular, and multimaterial structures simultaneously. The key to this ability lies in the use of a precursor cartridge that can stably preserve a multimaterial with a pre-defined configuration that can be simply embedded in a syringe-based printer head...
May 22, 2018: Biofabrication
https://www.readbyqxmd.com/read/29782609/low-cost-customized-cranioplasty-using-a-3d-digital-printing-model-a-case-report
#8
Abel De La Peña, Javier De La Peña-Brambila, Juan Pérez-De La Torre, Miguel Ochoa, Guillermo J Gallardo
Background: Cranial defects usually occur after trauma, neurosurgical procedures like decompressive craniotomy, tumour resections, infection and congenital defects. The purpose of cranial vault repair is to protect the underlying brain tissue, to reduce any localized pain and patient anxiety, and improve cranial aesthetics. Cranioplasty is a frequent neurosurgical procedure achieved with the aid of cranial prosthesis made from materials such as: titanium, autologous bone, ceramics and polymers...
2018: 3D printing in medicine
https://www.readbyqxmd.com/read/29781218/fabrication-of-single-gel-with-different-mechanical-stiffness-using-three-dimensional-mold
#9
Gulsan Ara Sathi Kazi, Kazi Anisur Rahman, Mahmoud Farahat, Takuya Matsumoto
The hydrogel is considering as functional substrates for three-dimensional (3D) environment mimicking the native tissue in vitro. To get the cell or tissue culture result in different stiffness, researchers are used separate gel at the different time. Sometimes these results are manipulated by surrounding environment. To overcome this, we prepared a single hydrogel with different young modulus using a 3D printed mold and cell culture and tissue culture was performed to check the functional capacity. In this proposed device we successfully produced a multi properties agarose hydrogel on a single platform...
May 20, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29777981/bare-footprint-metric-analysis-methods-for-comparison-and-identification-in-forensic-examinations-a-review-of-literature
#10
REVIEW
Richa Mukhra, Kewal Krishan, Tanuj Kanchan
Footprint is one of the most common types of physical evidence recovered at a crime scene. The forensic footprint evidence may play an important role in establishing the identity of a person; therefore, its examination is of prime importance. A link may be established by observing and comparing the morphological features of footprints with the perpetrator. These barefoot prints may be present as a two-dimensional print or a three-dimensional imprint depending on the substrate upon which they have been impressed upon and accordingly different methods and techniques are implemented in order to identify the questioned prints...
May 9, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29774184/a-systematic-review-of-clinical-value-of-three-dimensional-printing-in-renal-disease
#11
Zhonghua Sun, Dongting Liu
The aim of this systematic review is to analyse current literature related to the clinical value of three-dimensional (3D) printed models in renal disease. A literature search of PubMed and Scopus databases was performed to identify studies reporting the clinical application and usefulness of 3D printed models in renal disease. Fifteen studies were found to meet the selection criteria and were included in the analysis. Eight of them provided quantitative assessments with five studies focusing on dimensional accuracy of 3D printed models in replicating renal anatomy and tumour, and on measuring tumour volume between 3D printed models and original source images and surgical specimens, with mean difference less than 10%...
April 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29774140/three-dimensional-printing-in-maxillofacial-surgery-hype-versus-reality
#12
Alaa Aldaadaa, Nazanin Owji, Jonathan Knowles
Three-dimensional printing technology is getting more attention recently, especially in the craniofacial region. This is a review of literature enlightening the materials that have been used to date and the application of such technology within the scope of maxillofacial surgery.
January 2018: Journal of Tissue Engineering
https://www.readbyqxmd.com/read/29771086/-design-of-cross-sectional-anatomical-model-focused-on-drainage-pathways-of-paranasal-sinuses
#13
Y Zha, W Lv, Y L Gao, Z Z Zhu, Z Q Gao
Objective: To design and produce cross-sectional anatomical models of paranasal sinuses for the purpose of demonstrating drainage pathways of each nasal sinus for the young doctors. Method: We reconstructed the three-dimensional model of sinuses area based on CT scan data, and divided it into 5 thick cross-sectional anatomy models by 4 coronal plane,which cross middle points of agger nasi cell, ethmoid bulla, posterior ethmoid sinuses and sphenoid sinus respectively. Then a 3D printerwas used to make anatomical cross-sectional anatomical models...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29770294/three-dimensional-modelling-and-three-dimensional-printing-in-pediatric-and-congenital-cardiac-surgery
#14
REVIEW
Laszlo Kiraly
Three-dimensional (3D) modelling and printing methods greatly support advances in individualized medicine and surgery. In pediatric and congenital cardiac surgery, personalized imaging and 3D modelling presents with a range of advantages, e.g., better understanding of complex anatomy, interactivity and hands-on approach, possibility for preoperative surgical planning and virtual surgery, ability to assess expected results, and improved communication within the multidisciplinary team and with patients. 3D virtual and printed models often add important new anatomical findings and prompt alternative operative scenarios...
April 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29768847/synthesis-of-antioxidative-conductive-copper-inks-with-superior-adhesion
#15
Wei-Yang Ma, Yao-Yi Cheng, Jia-Kun Chen, Kai-Hsuan Chan, Zheng-Jie Lin, Wei-Hao Chou, Wei-Chen Chang
Conductive films have attracted much attention in the printed electronics industry. To date, expensive conductive silver inks have been utilized widely in these conductive films, which ultimately increase the cost. Hence the alternative low-cost copper inks will be of great interest in the future. This paper will present how to synthesize antioxidative conductive copper inks with superior adhesion to FR4 substrates. The antioxidative conductive copper inks were prepared by dispersing the antioxidative copper nanoparticles in diethylene glycol with the bisphenol-F type BEF170 epoxy resin as a binder and the Methyl-5-norbornene-2,3-dicarboxylic anhydride (NMA) as a curing agent, then were coated on FR4 substrates to form the copper films, followed by sintering at 250 °C in nitrogen atmosphere for 20 minutes...
January 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29768120/three-dimensionally-printed-pearl-powder-poly-caprolactone-composite-scaffolds-for-bone-regeneration
#16
Xu Zhang, Xiaoyu Du, Dejian Li, Rongguang Ao, Bin Yu, Baoqing Yu
Pearl has great potential as a natural biomaterial for bone tissue engineering, but it suffers from low porosity, difficulty in molding, and poor anti-buckling property. In this study, we used the 3-D printing technique to fabricate original pearl powder and PCL composite scaffolds with different concentrations of pearl powder. The four groups of scaffolds were termed PCL, 30% Pearl/PCL, 50% Pearl/PCL and 80% Pearl/PCL scaffolds according to the proportion of pearl powder. The samples were systematically investigated by scanning electron microscopy (SEM), wide-angle XRD, liquid substitution, Zwick static materials testing, and energy dispersive X-ray analysis...
May 16, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29768115/three-dimensional-printing-of-vitrification-loop-prototypes-for-aquatic-species
#17
Nolan J Tiersch, William M Childress, Terrence R Tiersch
Vitrification is a method of cryopreservation that freezes samples rapidly, while forming an amorphous solid ("glass"), typically in small (μL) volumes. The goal of this project was to create, by three-dimensional (3D) printing, open vitrification devices based on an elliptical loop that could be efficiently used and stored. Vitrification efforts can benefit from the application of 3D printing, and to begin integration of this technology, we addressed four main variables: thermoplastic filament type, loop length, loop height, and method of loading...
May 16, 2018: Zebrafish
https://www.readbyqxmd.com/read/29764458/cone-beam-computed-tomography-in-implant-dentistry-recommendations-for-clinical-use
#18
Reinhilde Jacobs, Benjamin Salmon, Marina Codari, Bassam Hassan, Michael M Bornstein
BACKGROUND: In implant dentistry, three-dimensional (3D) imaging can be realised by dental cone beam computed tomography (CBCT), offering volumetric data on jaw bones and teeth with relatively low radiation doses and costs. The latter may explain why the market has been steadily growing since the first dental CBCT system appeared two decades ago. More than 85 different CBCT devices are currently available and this exponential growth has created a gap between scientific evidence and existing CBCT machines...
May 15, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29763597/a-hem-o-lok-induced-tracheoesophageal-fistula-cured-by-temporary-airway-stenting-modified-with-three-dimensional-printing
#19
Yichao Han, Su Yang, Wei Huang, Zhongmin Wang, Hecheng Li
We present the case of a fistula between the trachea and the esophagogastric anastomosis in a 58-year-old male after esophagectomy. A Hem-o-Lok clip used at the time to ligate the azygos vein was discovered by esophagoscopy and bronchoscopy to be eroding into the both structures. A covered self-expandable Y-shaped metallic tracheobronchial stent was customized with a 3D printed airway model and inserted in place, with endoscopic injection of fibrin glue to the anastomotic site. 64 days after implantation, the stent was withdrawn with complete healing of the fistula...
May 12, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29761995/-the-progress-of-research-on-three-dimensional-printed-jaw-scaffolds
#20
REVIEW
Shuaishuai Cao, Miao Zhou
Large defects of jaw caused by tumor, trauma and so on in oral and maxillofacial region lead to facial deformity, language and chewing dysfunction, which severely damage the patient's life quality. Three-dimensional printing (3DP) is also named additive manufacturing (AM), which can print materials layer by layer to create three-dimensional objects. The complex shape of jaw defects can be accurately reconstructed using 3DP scaffold combined with image data, computer-aided-design and manufacture. It has specific advantages compared with traditional way of jaw reconstruction and has attracted much attention in the field of jaw tissue engineering recently...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
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