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https://www.readbyqxmd.com/read/28717599/improving-the-trajectory-of-transpedicular-transdiscal-lumbar-screw-fixation-with-a-computer-assisted-3d-printed-custom-drill-guide
#1
Zhen-Xuan Shao, Jian-Shun Wang, Zhong-Ke Lin, Wen-Fei Ni, Xiang-Yang Wang, Ai-Min Wu
Transpedicular transdiscal screw fixation is an alternative technique used in lumbar spine fixation; however, it requires an accurate screw trajectory. The aim of this study is to design a novel 3D-printed custom drill guide and investigate its accuracy to guide the trajectory of transpedicular transdiscal (TPTD) lumbar screw fixation. Dicom images of thirty lumbar functional segment units (FSU, two segments) of L1-L4 were acquired from the PACS system in our hospital (patients who underwent a CT scan for other abdomen diseases and had normal spine anatomy) and imported into reverse design software for three-dimensional reconstructions...
2017: PeerJ
https://www.readbyqxmd.com/read/28713738/three-dimensional-planning-and-reconstruction-of-the-mandible-in-children-with-craniofacial-microsomia-type-iii-using-costochondral-grafts
#2
Omri Emodi, Yair Israel, Michal Even Almos, Dror Aizenbud, John A Van Aalst, Adi Rachmiel
BACKGROUND: In craniofacial microsomia (CFM) Type III patients, autogenous costochondral grafts (CCG) are conventionally used for the reconstruction of the ramus and condyle. The aim of this study was to describe the use of CCG in children with CFM in terms of outcomes, growth patterns, and complications. MATERIALS AND METHODS: This is a retrospective study of nine, aged 4-12 years, patients with CFM Type III, who underwent reconstruction of the mandibular ramus condyle unit by CCG...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28710459/application-of-a-novel-three-dimensional-printing-genioplasty-template-system-and-its-clinical-validation-a-control-study
#3
Biao Li, Hongpu Wei, Feini Zeng, Jianfu Li, James J Xia, Xudong Wang
The purpose of this control study was to assess the accuracy and clinical validation of a novel genioplasty template system. Eighty-eight patients were enrolled and divided into 2 groups: experimental group (using genioplasty templates) and control group (without genioplasty templates). For the experimental group, the templates were designed based on computerized surgical plan and manufactured using three-dimensional printing technique. The template system included a cutting guide and a pair of repositioning guides...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28709790/corrective-osteotomy-for-malunited-diaphyseal-forearm-fractures-using-preoperative-3-dimensional-planning-and-patient-specific-surgical-guides-and-implants
#4
Ann-Maria Byrne, Bianca Impelmans, Veronique Bertrand, Annemieke Van Haver, Frederik Verstreken
PURPOSE: Three-dimensional planning based on computed tomography images of the malunited and the mirrored contralateral forearm allows preoperative simulations of corrective osteotomies, the fabrication of patient-specific osteotomy guides, and custom-made 3-dimensional printed titanium plates. This study aims to assess the precision and clinical outcome of this technique. METHODS: This was a prospective pilot study with 5 consecutive patients. The mean age at initial injury was 11 years (range, 4-16 years), and the mean interval from the time of injury to the time of corrective surgery was 32 months (range, 7-107 months)...
July 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28708733/an-assembled-prototype-multimaterial-three-dimensional-printed-model-of-the-neck-for-computed-tomography-and-ultrasound-guided-interventional-procedures
#5
Ramin Javan, Alexander L Cho
A low-cost, semirealistic, multimaterial prototype phantom of the neck was developed for computed tomography- and ultrasound-guided interventions, using three-dimensional (3D) printing with a variety of materials as well as through molding techniques. This dual-modality phantom can be used by trainees for practicing procedures and can also serve as a prototype for developing more complex and realistic 3D-printed models, particularly with the continued development and advancement in multimaterial 3D printing technologies...
July 13, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28704040/uniaxially-stretched-flexible-surface-plasmon-resonance-film-for-versatile-surface-enhanced-raman-scattering-diagnostics
#6
Kaichen Xu, Zuyong Wang, Chuan Fu Tan, Ning Kang, Lianwei Chen, Lei Ren, Eng San Thian, Ghim Wei Ho, Rong Ji, Minghui Hong
Surface enhanced Raman scattering (SERS) spectroscopy affords a rapid, highly sensitive and non-destructive approach for label-free and finger-print diagnosis of a wide range of chemicals. It is of great significance to develop large-area, uniform and environmentally friendly SERS substrates for in-situ identification of analytes on complex topological surfaces. In this work, we demonstrate a biodegradable flexible SERS film via irreversibly and longitudinally stretching metal deposited biocompatible poly (ɛ-caprolactone) film...
July 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28699346/probing-the-morphology-and-evolving-dynamics-of-3d-printed-nanostructures-using-high-speed-atomic-force-microscopy
#7
Chen Yang, Robert Winkler, Maja Dukic, Jie Zhao, Harald Plank, Georg E Fantner
Focused electron beam induced deposition (FEBID) has been demonstrated as a promising solution for synthesizing truly three-dimensional (3D) nanostructures. However, the lack of morphological feedback during growth complicates further development toward higher spatial fabrication precision. Here, we show that by combining in situ high speed atomic force microscopy (HS-AFM) with FEBID, morphologies in multistep fabrication process can be accessed. More importantly, the proposed method enables simultaneous imaging and fabrication operation, which opens new possibilities to investigate evolving mechanical properties of the deposit...
July 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28698814/a-patient-matched-entire-first-metacarpal-prosthesis-in-treatment-of-giant-cell-tumor-of-bone
#8
Thipachart Punyaratabandhu, Boonrat Lohwongwatana, Chedtha Puncreobutr, Arkaphat Kosiyatrakul, Puwadon Veerapan, Suriya Luenam
Giant cell tumor of the bones occurring in the first metacarpals frequently requires entire metacarpal resection due to the aggressive nature and high rate of recurrence. Bone reconstruction can be performed with autogenous bone grafts. Here we describe a new technique of reconstruction using a patient-matched three-dimensional printed titanium first metacarpal prosthesis. This prosthesis has a special design for ligament reconstruction in the proximal and distal portions. Good hand function and aesthetic appearance were maintained at a 24-month follow-up visit...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28692522/reconstructive-operation-of-nonsyndromic-multiple-suture-craniosynostosis-based-on-precise-virtual-plan-and-prefabricated-template
#9
Jian Ni, Bin Yang, Binghang Li
This report presents a case of a 4-year-old girl suffering from multiple-suture nonsyndromic craniosynostosis. The patient is characterized with fronto-orbital malformation and poor visual acuity. The preoperational three-dimensional computed tomography scan showed premature closure of the sagittal suture, bilateral coronal, and lambdoidal suture. The virtual surgical planning was performed before operation for the reposition of bone segments and communication with the patient's family. The navigational plate for reshaping was made based on the surgical plan with three-dimensional printed model...
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28691696/decellularized-extracellular-matrix-a-step-towards-the-next-generation-source-for-bioink-manufacturing
#10
Byoung Soo Kim, Hyeonji Kim, Ge Gao, Jinah Jang, Dong-Woo Cho
In tissue engineering, the need for hierarchical assembly of three-dimensional (3D) tissues becomes increasingly important, considering that a new technology is essential for advanced tissue fabrication. 3D cell printing has emerged as a powerful technology to recapitulate the microenvironment of native tissue, allowing for the precise deposition of multiple cells onto the pre-defined position. Parallel to these technological advances, seeking for an appropriate bioink to provide a suitable microenvironment supporting cellular activities has been into the spotlight...
July 10, 2017: Biofabrication
https://www.readbyqxmd.com/read/28691691/development-of-a-clay-based-bioink-for-3d-cell-printing-for-skeletal-application
#11
Tilman Ahlfeld, Gianluca Cidonio, David Kilian, Sarah Duin, Ashwini Rahul Akkineni, Jon I Dawson, Shoufeng Yang, Anja Lode, Richard Oreffo, Michael Gelinsky
Three-dimensional printing of cell-laden hydrogels has evolved as a promising approach on the route to patient-specific or complex tissue engineered constructs. However, it is still challenging to print structures with both, high shape fidelity and cell vitality. Herein, we used a synthetic nanosilicate clay, called Laponite, to build up scaffolds utilizing the extrusion-based method 3D plotting. By blending with alginate and methylcellulose, a bioink was developed which allowed easy extrusion, achieving scaffolds with high printing fidelity...
July 10, 2017: Biofabrication
https://www.readbyqxmd.com/read/28689470/analysis-and-comparison-of-wrist-splint-designs-using-the-finite-element-method-multi-material-three-dimensional-printing-compared-to-typical-existing-practice-with-thermoplastics
#12
Aitor Cazon, Sarah Kelly, Abby M Paterson, Richard J Bibb, R Ian Campbell
Rheumatoid arthritis is a chronic disease affecting the joints. Treatment can include immobilisation of the affected joint with a custom-fitting splint, which is typically fabricated by hand from low temperature thermoplastic, but the approach poses several limitations. This study focused on the evaluation, by finite element analysis, of additive manufacturing techniques for wrist splints in order to improve upon the typical splinting approach. An additive manufactured/3D printed splint, specifically designed to be built using Objet Connex multi-material technology and a virtual model of a typical splint, digitised from a real patient-specific splint using three-dimensional scanning, were modelled in computer-aided design software...
July 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28688825/three-dimensional-bio-printed-scaffold-sleeves-with-mesenchymal-stem-cells-for-enhancement-of-tendon-to-bone-healing-in-anterior-cruciate-ligament-reconstruction-using-soft-tissue-tendon-graft
#13
Sin Hyung Park, Yeong-Jin Choi, Sang Won Moon, Byung Hoon Lee, Jin-Hyung Shim, Dong-Woo Cho, Joon Ho Wang
PURPOSE: To investigate the efficacy of the insertion of 3-dimensional (3D) bio-printed scaffold sleeves seeded with mesenchymal stem cells (MSCs) to enhance osteointegration between the tendon and tunnel bone in anterior cruciate ligament (ACL) reconstruction in a rabbit model. METHODS: Scaffold sleeves were fabricated by 3D bio-printing. Before ACL reconstruction, MSCs were seeded into the scaffold sleeves. ACL reconstruction with hamstring tendon was performed on both legs of 15 adult rabbits (aged 12 weeks)...
July 5, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28688157/the-application-of-3-dimensional-printing-for-preoperative-planning-in-oral-and-maxillofacial-surgery-in-dogs-and-cats
#14
Jenna N Winer, Frank J M Verstraete, Derek D Cissell, Steven Lucero, Kyriacos A Athanasiou, Boaz Arzi
OBJECTIVE: To describe the application of 3-dimensional (3D) printing in advanced oral and maxillofacial surgery (OMFS) and to discuss the benefits of this modality in surgical planning, student and resident training, and client education. STUDY DESIGN: Retrospective case series. ANIMALS: Client-owned dogs (n = 28) and cats (n = 4) with 3D printing models of the skulls. METHODS: The medical records of 32 cases with 3D printing prior to major OMFS were reviewed...
July 8, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28686244/3d-printed-porous-ceramic-scaffolds-for-bone-tissue-engineering-a-review
#15
REVIEW
Yu Wen, Sun Xun, Meng Haoye, Sun Baichuan, Chen Peng, Liu Xuejian, Zhang Kaihong, Yang Xuan, Peng Jiang, Lu Shibi
This study summarizes the recent research status and development of three-dimensional (3D)-printed porous ceramic scaffolds in bone tissue engineering. Recent literature on 3D-printed porous ceramic scaffolds was reviewed. Compared with traditional processing and manufacturing technologies, 3D-printed porous ceramic scaffolds have obvious advantages, such as enhancement of the controllability of the structure or improvement of the production efficiency. More sophisticated scaffolds were fabricated by 3D printing technology...
July 7, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28685477/design-and-implementation-of-a-prototype-head-and-neck-phantom-for-the-performance-evaluation-of-gamma-imaging-systems
#16
Mohammed S Alqahtani, John E Lees, Sarah L Bugby, Piyal Samara-Ratna, Aik H Ng, Alan C Perkins
BACKGROUND: A prototype anthropomorphic head and neck phantom has been designed to simulate the adult head and neck anatomy including some internal organs and tissues of interest, such as thyroid gland and sentinel lymph nodes (SLNs). The design of the head and neck phantom includes an inner jig holding the simulated SLNs and thyroid gland. The thyroid gland structure was manufactured using three-dimensional (3D) printing taking into consideration the morphology and shape of a healthy adult thyroid gland...
December 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/28682875/the-use-of-3d-printed-titanium-mesh-tray-in-treating-complex-comminuted-mandibular-fractures-a-case-report
#17
Junli Ma, Limin Ma, Zhifa Wang, Xiongjie Zhu, Weijian Wang
RATIONALE: Precise bony reduction and reconstruction of optimal contour in treating comminuted mandibular fractures is very difficult using traditional techniques and devices. The aim of this report is to introduce our experiences in using virtual surgery and three-dimensional (3D) printing technique in treating this clinical challenge. PATIENT CONCERNS: A 26-year-old man presented with severe trauma in the maxillofacial area due to fall from height. DIAGNOSIS: Computed tomography images revealed middle face fractures and comminuted mandibular fracture including bilateral condyles...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28682611/forbidden-chemistry-two-photon-pathway-in-2-2-cycloaddition-of-maleimides
#18
Mikhail V Tsurkan, Christiane Jungnickel, Michael Schlierf, Carsten Werner
Two-photon excitation provides high spatial resolution in three dimensions of the corresponding chemical or physical processes, allowing submicrometer structuring in stereolithography and three-dimensional (3D) microfabrication. While studying two-photon structuring applications, we observed an undescribed phenomenon in photochemistry that dictates reactivity of maleimide groups in two-photon mode. A low-absorbance transition formerly ignored in classical photochemistry has been found for maleimides. This transition was assigned to symmetry-breaking donor-acceptor complex formation, which revealed a formally forbidden pathway in [2+2] cycloaddition reactions of maleimide moieties...
July 18, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28680970/nbiochip-a-lab-on-a-chip-platform-of-mono-and-polymicrobial-biofilms-for-high-throughput-downstream-applications
#19
Anand Srinivasan, Nelson S Torres, Kai P Leung, Jose L Lopez-Ribot, Anand K Ramasubramanian
Current in vitro techniques for the culture of microorganisms, and particularly of delicate microbial biofilms, are still mostly limited to low-density plates and manual labor and are not amenable to automation and true high-throughput (HT) applications. We have developed a novel fully automated platform for the formation of mono- and polymicrobial biofilms of Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans at the nanoscale level. The nBioChip is robotically printed, robustly handled, and scanned using a standard microarray reader...
May 2017: MSphere
https://www.readbyqxmd.com/read/28673795/use-of-3d-reconstruction-cloacagrams-and-3d-printing-in-cloacal-malformations
#20
Jennifer J Ahn, Margarett Shnorhavorian, Anne-Marie E Amies Oelschlager, Beth Ripley, Giridhar M Shivaram, Jeffrey R Avansino, Paul A Merguerian
INTRODUCTION: Cloacal anomalies are complex to manage, and the anatomy affects prognosis and management. Assessment historically includes examination under anesthesia, and genitography is often performed, but these do not consistently capture three-dimensional (3D) detail or spatial relationships of the anatomic structures. Three-dimensional reconstruction cloacagrams can provide a high level of detail including channel measurements and the level of the cloaca (<3 cm vs. >3 cm), which typically determines the approach for surgical reconstruction and can impact long-term prognosis...
June 20, 2017: Journal of Pediatric Urology
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