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https://www.readbyqxmd.com/read/28738365/advances-in-box-surgery-for-obstructive-sleep-apnea-genioglossus-advancement-hyoid-suspension-and-maxillomandibular-advancement
#1
Yau Hong Goh, Winston Tan, Victor James Abdullah, Sung Wan Kim
Box surgery for obstructive sleep apnea (OSA) patients consists of mandibular surgery, including genioglossus advancement, hyoid suspension, and maxillomandibular advancement, as an airway reconstruction. This surgery was developed in the early 1980s. Thereafter, techniques were modified in each surgery for the enhancement of outcome and prevention of complications. However, the indication for surgery remains poorly defined due to the dynamicity of the upper airway, variability of the phenotype in OSA patients, and absence of a representative method for the obstruction site in the upper airway...
2017: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28732224/three-dimensional-changes-in-the-upper-airway-of-skeletal-class-iii-patients-after-different-orthognathic-surgical-procedures
#2
Yuxue Yang, Kai Yang, Ying Zhao
PURPOSE: We hypothesized that 3-dimensional changes in the upper airway of patients with skeletal Class III malocclusion are different after mandibular setback and maxillary advancement (MSMA) compared with mandibular setback (MS) and that upper airway changes and the amount of jaw movement are correlated. PATIENTS AND METHODS: Skeletal Class III patients who underwent MS surgery or MSMA surgery were included in this retrospective cohort study. Cone beam computed tomography scans were acquired before and 3 months after surgery...
June 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28688869/ankylosis-of-temporomandibular-joints-after-mandibular-distraction-osteogenesis-in-patients-with-nager-syndrome-report-of-two-cases-and-literature-review
#3
REVIEW
Cheng Chun Wu, Daisuke Sakahara, Keisuke Imai
Nager syndrome, also known as Nager acrofacial dysostosis, was first described by Nager and de Reynier in 1948. The patients commonly present with micrognathia, and a preventive tracheostomy is necessary when there are symptoms of upper airway obstruction. Mandibular distraction osteogenesis is considered as an effective procedure, which not only improves micrognathia but also minimizes the chances of tracheostomy. However, mandibular distraction osteogenesis has some complications such as relapse, teeth injury, infection, and injury of the temporomandibular joints (TMJs)...
February 7, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28686091/correlation-between-the-position-of-hyoid-bone-and-subregions-of-the-pharyngeal-airway-space-in-lateral-cephalometry-and-cone-beam-computed-tomography
#4
Eliana Dantas da Costa, Gina Delia Roque-Torres, Danieli Moura Brasil, Frab Noberto Bóscolo, Solange Maria de Almeida, Glaucia Maria Bovi Ambrosano
OBJECTIVE: To correlate the pharyngeal airway subregions with the positioning of the hyoid bone. MATERIAL AND METHODS: The study examined 107 lateral cephalometric (LC) and cone beam computed tomography (CBCT) images. Linear and volumetric measurements of the pharyngeal subregions were made and correlated to linear measurements using hyoid triangle analysis on images of LC and multiplanar (MPR) and three-dimensional (3D) reconstructions of CBCT. RESULTS: There was significant correlation between linear measurements of the pharyngeal subregions and hyoid bone position in LC images and in MPR and 3D reconstructions of the CBCT...
July 7, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28676839/mechanisms-underlying-improvement-in-obstructive-sleep-apnea-syndrome-by-uvulopalatopharyngoplasty
#5
Takahisa Yamamoto, Naoko Fujii, Yoichi Nishimura, Noboru Iwata, Seiichi Nakata
In a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstructive sleep apnea syndrome (OSAS) by UPPP. We present an additional case involving a patient with OSAS treated using UPPP. Morphological and numerical parameter changes after surgery were compared with the corresponding preoperative values...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28670393/chronic-intermittent-hypoxia-decreases-pulmonary-clearance-of-99m-tc-labelled-particulate-matter-in-mice
#6
Cuiping Fu, Huan Lu, Xu Wu, Jie Liu, Chengying Liu, Zilong Liu, Wei Yuan, Jian Zhou, Shanqun Li
BACKGROUND: Obstructive sleep apnea-hypopnea syndrome (OSAHS) could cause systematic inflammation including pulmonary inflammatory response, whereas the influence of OSAHS in pulmonary clearance ability remains unknown. The main pathophysiological feature of OSAHS is chronic intermittent hypoxia (CIH). The goal of this study is to clarify the airway clearance of particulate matter (PM) in CIH mice, and to explore the potential mechanism. METHODS: Balb/c mice were divided into a CIH group and a control group, exposed to intermittent hypoxia and air chamber, respectively...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28657201/comparison-of-low-and-ultra-low-dose-computed-tomography-protocols-for-quantitative-lung-and-airway-assessment
#7
Emily Hammond, Chelsea Sloan, John D Newell, Jered P Sieren, Melissa Saylor, Craig Vidal, Shayna Hogue, Frank De Stefano, Alexa Sieren, Eric A Hoffman, Jessica C Sieren
PURPOSE: Quantitative computed tomography (CT) measures are increasingly being developed and used to characterize lung disease. With recent advances in CT technologies, we sought to evaluate the quantitative accuracy of lung imaging at low and ultra-low radiation doses with the use of iterative reconstruction (IR), tube current modulation (TCM), and spectral shaping. METHODS: We investigated the effect of five independent CT protocols reconstructed with IR on quantitative airway measures and global lung measures using an in-vivo large animal model as a human subject surrogate...
June 28, 2017: Medical Physics
https://www.readbyqxmd.com/read/28640732/do-nurse-staffing-levels-affect-patient-mortality-in-acute-secondary-care
#8
Barry Hill
This systematic literature review explores and considers whether registered nurse staffing levels affect patient mortality in acute secondary care settings. A discussion makes particular reference to the philosophical foundations of contrasting research approaches used within the literature. At the time of writing, the author was a modern matron for surgery, managing the ear, nose and throat; head and neck; airway; and reconstructive plastic surgery services in a large acute teaching hospital in central London...
June 22, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28629919/comparing-pulmonary-nodule-location-during-electromagnetic-bronchoscopy-with-predicted-location-on-the-basis-of-two-virtual-airway-maps-at-different-phases-of%C3%A2-respiration
#9
Brian S Furukawa, Nicholas J Pastis, Nichole T Tanner, Alexander Chen, Gerard A Silvestri
BACKGROUND: Electromagnetic navigational bronchoscopy (ENB) is guided bronchoscopy to pulmonary nodules (PN) that relies on a preprocedural chest CT to create a three-dimensional (3D) virtual airway map. The CT is traditionally done at a full inspiratory breath hold (INSP), but the procedure is performed while the patient tidal breaths, when lung volumes are closer to functional residual capacity. Movement of a PN from INSP to expiration (EXP) has been shown to average 17.6 mm. Therefore, the hypothesis of this study is that preprocedural virtual maps built off a CT closer to physiological lung volumes during bronchoscopy may better represent the actual 3D location of a PN...
June 16, 2017: Chest
https://www.readbyqxmd.com/read/28623043/nasal-airway-evaluation-in-obstructive-sleep-apnoea-patients-volumetric-tomography-and-endoscopic-findings
#10
M M Rodrigues, M F R Gabrielli, O A Garcia Junior, V A Pereira Filho, L A Passeri
Obstructive sleep apnoea (OSA) results from the recurrent collapse of the upper airway during sleep. Nasal abnormalities influence the stability of the pharynx. The aim of this study was to evaluate the volumetric and anatomical changes of the nasal cavity in patients with OSA. The Nasal Obstruction Symptom Evaluation (NOSE) scale was used to grade nasal obstruction. Sleep-related breathing disorders were evaluated by polysomnography. The nasal airway volume was obtained from computed tomography scans through volumetric reconstruction of the nasal airway...
June 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28610885/three-dimensional-printed-bioengineered-tracheal-grafts-preclinical-results-and-potential-for-human-use
#11
Sadiq S Rehmani, Adnan M Al-Ayoubi, Adil Ayub, Michael Barsky, Erik Lewis, Raja Flores, Robert Lebovics, Faiz Y Bhora
BACKGROUND: We aimed to develop a process using three-dimensional (3D) printing to create bioengineered tracheal grafts (BETGs) for reconstruction of anterior tracheal defects in a large-animal model (porcine) that would have translational relevance for potential human use. METHODS: Preoperative computed tomographic scans were used to create virtual 3D models of the animal airways. Anatomically scaled tracheal grafts were subsequently developed using 3D-printed polycaprolactone and extracellular matrix...
June 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28595251/use-of-turn-in-skin-flaps-for-nasal-lining-reconstruction
#12
Memet Yazar, Sevgi Kurt Yazar, Erol Kozanoğlu, Murat Diyarbakırlıoğlu, Hikmet İhsan Eren
BACKGROUND: Reconstruction of the nasal lining is the most difficult part of complex nasal reconstruction because the mucosa has a unique texture and fineness. Many techniques, ranging from skin grafts to local flaps, have been applied for the reconstruction of the mucosa. In some cases, even free flaps have been used. OBJECTIVE: The aim of this study was to discuss the feasibility of using turn-in flaps in nasal reconstruction. MATERIALS AND METHODS: Seventeen patients with full-thickness nasal defects underwent reconstruction with turn-in flaps...
June 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28590308/perioperative-factors-related-to-the-severity-of-vocal-cord-paralysis-after-thoracic-cardiovascular-surgery-a-retrospective-review
#13
Hiroki Taenaka, Sho Carl Shibata, Kenta Okitsu, Takeshi Iritakenishi, Tatsuyuki Imada, Akinori Uchiyama, Yuji Fujino
BACKGROUND: Vocal cord paralysis (VCP) is a rare complication of thoracic cardiovascular surgery. In severe cases, life-threatening airway obstruction may occur. OBJECTIVE: To evaluate the incidence and severity of VCP among patients who underwent thoracic cardiovascular surgery and to identify possible risk factors. DESIGN: Single-centre retrospective review of adult patients. SETTING: Osaka University Hospital, Suita, Japan, from January 2013 to August 2015...
July 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28577852/fascia-temporalis-free-flap-for-cricotracheal-reconstruction-a-novel-approach
#14
Bertrand Baujat, Samuel Struk, Maria Lesnik, Olivier de Crouy Chanel, Jonathan Barbut, Marine Lefevre, Sophie Périé, Jean Lacau St Guily
BACKGROUND: The aim of tracheal reconstruction is to provide an airtight and noncollapsible airway covered with a suitable epithelial lining. To date, no ideal treatment is available for large tracheal defects. METHODS: We report 4 patients who underwent one-stage reconstruction for a cricotracheal stenosis with a free temporoparietal fascia flap and costal cartilage grafts. RESULTS: Closure of tracheostoma was achieved for all patients. The main advantage of this flap compared with the free radial forearm flap is that it supplies a more suitable lining allowing the reepithelialization process with respiratory epithelium...
June 1, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28570032/free-breathing-pediatric-chest-mri-performance-of-self-navigated-golden-angle-ordered-conical-ultrashort-echo-time-acquisition
#15
Evan J Zucker, Joseph Y Cheng, Anshul Haldipur, Michael Carl, Shreyas S Vasanawala
PURPOSE: To assess the feasibility and performance of conical k-space trajectory free-breathing ultrashort echo time (UTE) chest magnetic resonance imaging (MRI) versus four-dimensional (4D) flow and effects of 50% data subsampling and soft-gated motion correction. MATERIALS AND METHODS: Thirty-two consecutive children who underwent both 4D flow and UTE ferumoxytol-enhanced chest MR (mean age: 5.4 years, range: 6 days to 15.7 years) in one 3T exam were recruited...
June 1, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28544662/tracheal-replacement-therapy-with-a-stem-cell-seeded-graft-lessons-from-compassionate-use-application-of-a-gmp-compliant-tissue-engineered-medicine
#16
Martin J Elliott, Colin R Butler, Aikaterini Varanou-Jenkins, Leanne Partington, Carla Carvalho, Edward Samuel, Claire Crowley, Peggy Lange, Nicholas J Hamilton, Robert E Hynds, Tahera Ansari, Paul Sibbons, Anja Fierens, Claire McLaren, Derek Roebuck, Colin Wallis, Nagarajan Muthialu, Richard Hewitt, David Crabbe, Sam M Janes, Paolo De Coppi, Mark W Lowdell, Martin A Birchall
Tracheal replacement for the treatment of end-stage airway disease remains an elusive goal. The use of tissue-engineered tracheae in compassionate use cases suggests that such an approach is a viable option. Here, a stem cell-seeded, decellularized tissue-engineered tracheal graft was used on a compassionate basis for a girl with critical tracheal stenosis after conventional reconstructive techniques failed. The graft represents the first cell-seeded tracheal graft manufactured to full good manufacturing practice (GMP) standards...
June 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28523349/diagnosis-of-bronchiectasis-and-airway-wall-thickening-in-children-with-cystic-fibrosis-objective-airway-artery-quantification
#17
Wieying Kuo, Marleen de Bruijne, Jens Petersen, Kazem Nasserinejad, Hadiye Ozturk, Yong Chen, Adria Perez-Rovira, Harm A W M Tiddens
OBJECTIVES: To quantify airway and artery (AA)-dimensions in cystic fibrosis (CF) and control patients for objective CT diagnosis of bronchiectasis and airway wall thickness (AWT). METHODS: Spirometer-guided inspiratory and expiratory CTs of 11 CF and 12 control patients were collected retrospectively. Airway pathways were annotated semi-automatically to reconstruct three-dimensional bronchial trees. All visible AA-pairs were measured perpendicular to the airway axis...
May 18, 2017: European Radiology
https://www.readbyqxmd.com/read/28518105/murine-lymphocyte-labeling-by-64cu-antibody-receptor-targeting-for-in-vivo-cell-trafficking-by-pet-ct
#18
Sabrina H L Hoffmann, Andreas Maurer, Dorothea I Reck, Gerald Reischl, Bernd J Pichler, Manfred Kneilling, Christoph M Griessinger
This protocol illustrates the production of (64)Cu and the chelator conjugation/radiolabeling of a monoclonal antibody (mAb) followed by murine lymphocyte cell culture and (64)Cu-antibody receptor targeting of the cells. In vitro evaluation of the radiolabel and non-invasive in vivo cell tracking in an animal model of an airway delayed-type hypersensitivity reaction (DTHR) by PET/CT are described. In detail, the conjugation of a mAb with the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is shown...
April 29, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28504356/bronchoscopy-in-children-with-tetralogy-of-fallot-pulmonary-atresia-and-major-aortopulmonary-collaterals
#19
Douglas R Sidell, Andrew M Koth, Holly Bauser-Heaton, Doff B McElhinney, Lisa Wise-Faberowski, Michael C Tracy, Frank L Hanley, Ritu Asija
OBJECTIVE: Children with Tetralogy of Fallot, Pulmonary Atresia, and Major Aortopulmonary Collaterals (TOF/PA/MAPCAs) undergoing unifocalization surgery are at risk for developing more postoperative respiratory complications than children undergoing other types of congenital heart surgery. Bronchoscopy is used in the perioperative period for diagnostic and therapeutic purposes. In this study, we describe bronchoscopic findings and identify factors associated with selection for bronchoscopy...
May 15, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28445200/the-nasal-tip-rotation-flap-for-reconstruction-of-the-lateral-nasal-tip-anterior-ala-and-soft-triangle-the-authors-experience-with-55-patients
#20
Anastasia Benoit, S Tyler Hollmig, Brian C Leach
BACKGROUND: Defects of the lateral nasal tip, anterior ala, and soft triangle subunits lack reconstructive options that are consistently satisfactory. For such defects, the novel anterior-based nasal tip rotation flap provides functional and aesthetic results in a single operative session. OBJECTIVE: To describe the authors' experience with the nasal tip rotation flap, including patient selection and design modifications to enhance aesthetic success. METHODS: An IRB-approved retrospective database review of nasal tip rotation flap repairs was performed at the Medical University of South Carolina and Stanford University Medical Center...
April 24, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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