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airway reconstruction

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https://www.readbyqxmd.com/read/27871704/accuracy-and-reliability-of-orthodontists-using-cone-beam-computerized-tomography-for-assessment-of-adenoid-hypertrophy
#1
Camila Pachêco-Pereira, Noura A Alsufyani, Michael Major, Giseon Heo, Carlos Flores-Mir
INTRODUCTION: Our objectives were to evaluate the reliability of agreement between orthodontists, with various degrees of cone-beam computed tomography (CBCT) imaging manipulation comfort, in classifying adenoid hypertrophy through CBCT generated images and also to determine how accurate orthodontists are compared with the gold standard diagnosis, nasopharyngoscopy. METHODS: This was a cross-sectional study in which a randomized list of board-certified orthodontists evaluated different degrees of adenoid hypertrophy of a stratified sampling of 10 scans...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27871304/respiratory-viral-infections-and-host-responses-insights-from-genomics
#2
REVIEW
Niamh M Troy, Anthony Bosco
Respiratory viral infections are a leading cause of disease and mortality. The severity of these illnesses can vary markedly from mild or asymptomatic upper airway infections to severe wheezing, bronchiolitis or pneumonia. In this article, we review the viral sensing pathways and organizing principles that govern the innate immune response to infection. Then, we reconstruct the molecular networks that differentiate symptomatic from asymptomatic respiratory viral infections, and identify the underlying molecular drivers of these networks...
November 21, 2016: Respiratory Research
https://www.readbyqxmd.com/read/27867870/thyroid-cancer-with-tracheal-invasion-a-pathological-estimation
#3
Vincenzo Pappalardo, Stefano La Rosa, Andrea Imperatori, Nicola Rotolo, Maria Laura Tanda, Andrea Sessa, Lorenzo Dominioni, Gianlorenzo Dionigi
We review the clinical and pathologic features of seven cases of papillary carcinoma of the thyroid that invaded the trachea and were treated by thyroidectomy, airway resection with reconstructive surgery over an interval of 15 years. We depicted the peculiarity of invasion of well differentiated papillary thyroid carcinoma (PTC) cells is perpendicularly oriented to the tracheal lumen, in between cartilaginous rings, along blood vessels and collagen fibers. Tracheal rings appear non-infiltrated in all histological sections of well differentiated PTC infiltrating the trachea...
October 2016: Gland Surgery
https://www.readbyqxmd.com/read/27863622/objective-characterization-of-airway-dimensions-using-image-processing
#4
Victoria K Pepper, Christian Francom, Cameron A Best, Ekene Onwuka, Nakesha King, Eric Heuer, Nathan Mahler, Jonathan Grischkan, Christopher K Breuer, Tendy Chiang
OBJECTIVES: With the evolution of medical and surgical management for pediatric airway disorders, the development of easily translated techniques of measuring airway dimensions can improve the quantification of outcomes of these interventions. We have developed a technique that improves the ability to characterize endoscopic airway dimensions using common bronchoscopic equipment and an open-source image-processing platform. METHODS: We validated our technique of Endoscopic Airway Measurement (EAM) using optical instruments in simulation tracheas...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27858077/-cone-beam-computed-tomography-evaluation-of-short-and-long-term-airway-changes-in-patients-with-skeletal-class-%C3%A2-malocclusion-treated-by-orthodontic-therapy-and-bimaxillary-surgery-with-or-without-mandibular-setback-surgery
#5
Hong-Wei Wang, Li-Yan Li, Su-Qing Qi, Ming Yan
PURPOSE: To evaluate the short-term and long-term effects of pharyngeal airway in skeletal Class Ⅲ malocclusion patients who underwent bimaxillary surgery or isolated mandibular setback-orthodontic treatment. METHODS: The sample included 54 patients (28 males, 26 females) who were diagnosed with skeletal Class Ⅲ malocclusion. Patents in group A (n=28) underwent mandibular setback surgery and orthodontic treatment. Cone-beam CT (CBCT) was taken at one week before treatment (T0), 6 months (T1) and 3 years after surgery (T2)...
August 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27833870/use-of-conchal-cartilages-for-laryngotracheal-stenosis-experiences-at-a-tertiary-care-hospital-of-eastern-india
#6
Santosh Kumar Swain, Neha Singh, Rankanidhi Samal, Santosh Kumar Pani, Mahesh Chandra Sahu
To describe the experience of anterior cricotracheal split with insertion of conchal cartilage graft in the treatment of subglottic and tracheal stenosis at a tertiary care hospital of eastern India. Six patients were included in the study, in the age group of 20-48 years. Out of which five patients were successfully decannulated after 3 months of laryngotracheal reconstruction with help of conchal cartilage. One case was undergone resection anastomosis after failure of the above technique. Successful restoration of the airway with decannulation in five cases and failure in one case...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27806589/real-time-4d-dose-reconstruction-for-tracked-dynamic-mlc-deliveries-for-lung-sbrt
#7
Cornelis Ph Kamerling, Martin F Fast, Peter Ziegenhein, Martin J Menten, Simeon Nill, Uwe Oelfke
PURPOSE: This study provides a proof of concept for real-time 4D dose reconstruction for lung stereotactic body radiation therapy (SBRT) with multileaf collimator (MLC) tracking and assesses the impact of tumor tracking on the size of target margins. METHODS: The authors have implemented real-time 4D dose reconstruction by connecting their tracking and delivery software to an Agility MLC at an Elekta Synergy linac and to their in-house treatment planning software (TPS)...
November 2016: Medical Physics
https://www.readbyqxmd.com/read/27804241/towards-reconstruction-of-epithelialized-cartilages-from-autologous-adipose-tissue-derived-stem-cells
#8
Sophie E P New, Amel Ibrahim, Leonardo Guasti, Eleonora Zucchelli, Martin Birchall, Neil W Bulstrode, Alexander M Seifalian, Patrizia Ferretti
Deformities of the upper airways, including those of the nose and throat, are typically corrected by reconstructive surgery. The use of autologous somatic stem cells for repair of defects could improve quality and outcomes of such operations. The present study explored the ability of paediatric adipose-derived stem cells (pADSCs), a readily available source of autologous stem cells, to generate a cartilage construct with a functional epithelium. Paediatric ADSCs seeded on the biodegradable nanocomposite polymer, polyhedral oligomeric silsesquioxane poly(ϵ-caprolactone-urea) urethane (POSS-PCL), proliferated and differentiated towards mesenchymal lineages...
November 1, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27796843/energy-efficient-monitoring-of-metered-dose-inhaler-usage
#9
Aris S Lalos, John Lakoumentas, Anastasios Dimas, Konstantinos Moustakas
Life-long chronic inflammatory diseases of the airways, such as asthma and Chronic Obstructive Pulmonary Disease, are very common worldwide, affecting people of all ages, race and gender. One of the most important aspects for the effective management of asthma is medication adherence which is defined as the extent to which patients follow their prescribed action plan and use their inhaler correctly. Wireless telemonitoring of the medication adherence can facilitate early diagnosis and management of these diseases through the use of an accurate and energy efficient mHealth system...
December 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27792099/indications-for-elective-tracheostomy-in-reconstructive-surgery-in-patients-with-oral-cancer
#10
Yoav Leiser, Michal Barak, Yasmine Ghantous, Noam Yehudai, Imad Abu El-Naaj
BACKGROUND: Oral cancer surgery carries a high risk of upper airway obstruction; yet optimal airway management approach remains controversial. AIM OF STUDY: The purpose of the present study was to evaluate the use of tracheostomy in oncological patients undergoing oral cancer surgery with intra oral flap reconstruction. METHODS: The study cohort included 75 patients with oral cancer, who underwent major intraoral resections and reconstruction with vascularized flaps...
October 27, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27776743/open-airway-reconstruction-in-adults-outcomes-and-prognostic-factors
#11
Marianne Abouyared, Mikhaylo Szczupak, Eric Barbarite, Zoukaa B Sargi, David E Rosow
PURPOSE: The purpose was to assess the success of open tracheal resection and re-anastomosis for non-malignant tracheal stenosis in adults. Successful operations were defined as T-tube or tracheostomy-free status by 6months post-operatively. MATERIALS AND METHODS: Retrospective chart review was performed and data were recorded in a de-identified manner. The primary outcome was T-tube or tracheostomy-free status by 6months following tracheal resection. Clinical and demographic characteristics were evaluated as potential prognostic variables...
September 7, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27772613/a-novel-technique-for-laryngotracheal-reconstruction-for-idiopathic-subglottic-stenosis
#12
Anna M Ciccone, Camilla Vanni, Giulio Maurizi, Antonio D'Andrilli, Stylianos Korasidis, Mohsen Ibrahim, Claudio Andreetti, Federico Venuta, Erino A Rendina
Idiopathic subglottic stenosis is the most challenging condition in the field of upper airway reconstruction. We describe a successful novel technique for enlarging the airway space at the site of the laryngotracheal anastomosis in very high-level reconstructions.
November 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27751243/repair-of-large-airway-defects-with-bioprosthetic-materials
#13
Brooks V Udelsman, Jessica Eaton, Ashok Muniappan, Christopher R Morse, Cameron D Wright, Douglas J Mathisen
OBJECTIVE: Patients with complicated airway defects that exceed the limits of primary repair represent a challenging clinical problem and require alternative techniques for repair. The aim of this study was to evaluate bioprosthetic reconstruction of large tracheal and bronchial defects. METHODS: Retrospective chart review of patients treated at a single tertiary center from 2008 to 2015 who underwent repair of tracheal or bronchial defects with a bioprosthetic device, namely aortic homograft or acellular dermal matrix...
November 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27725841/numerical-investigation-of-flow-characteristics-in-the-obstructed-realistic-human-upper-airway
#14
Xingli Liu, Weiwei Yan, Yang Liu, Yat Sze Choy, Yikun Wei
The flow characteristics in the realistic human upper airway (HUA) with obstruction that resulted from pharyngeal collapse were numerically investigated. The 3D anatomically accurate HUA model was reconstructed from CT-scan images of a Chinese male patient (38 years, BMI 25.7). The computational fluid dynamics (CFD) with the large eddy simulation (LES) method was applied to simulate the airflow dynamics within the HUA model in both inspiration and expiration processes. The laser Doppler anemometry (LDA) technique was simultaneously adopted to measure the airflow fields in the HUA model for the purpose of testifying the reliability of LES approach...
2016: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/27699539/the-role-of-conventional-surgery-in-oropharyngeal-cancer
#15
Wojciech Golusinski
Anatomically, the oropharynx can be divided into four subsites: the soft palate, pharyngeal wall, base of tongue, and the tonsillar complex. Surgical access to these tumours is often challenging due to the anatomic localization. For this reason, such tumours were traditionally managed with open surgical techniques, usually involving a mandibulotomy, to provide better visualization and access to the oropharynx, followed by free-flap reconstruction of the oropharyngeal defect. However, the invasiveness of this approach could lead to significant morbidity, including speech, swallowing, and airway dysfunction, in addition to poor cosmetic outcomes...
2017: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27697371/evaluation-of-model-based-methods-in-estimating-respiratory-mechanics-in-the-presence-of-variable-patient-effort
#16
Daniel P Redmond, Yeong Shiong Chiew, Vincent Major, J Geoffrey Chase
Monitoring of respiratory mechanics is required for guiding patient-specific mechanical ventilation settings in critical care. Many models of respiratory mechanics perform poorly in the presence of variable patient effort. Typical modelling approaches either attempt to mitigate the effect of the patient effort on the airway pressure waveforms, or attempt to capture the size and shape of the patient effort. This work analyses a range of methods to identify respiratory mechanics in volume controlled ventilation modes when there is patient effort...
September 23, 2016: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27692428/new-algorithm-for-semiautomatic-segmentation-of-nasal-cavity-and-pharyngeal-airway-in-comparison-with-manual-segmentation-using-cone-beam-computed-tomography
#17
Noura A Alsufyani, Andy Hess, Michelle Noga, Nilanjan Ray, Mohammed A Q Al-Saleh, Manuel O Lagravère, Paul W Major
INTRODUCTION: Our objectives were to assess reliability, validity, and time efficiency of semiautomatic segmentation using Segura software of the nasal and pharyngeal airways, against manual segmentation with point-based analysis with color mapping. METHODS: Pharyngeal and nasal airways from 10 cone-beam computed tomography image sets were segmented manually and semiautomatically using Segura (University of Alberta, Edmonton, Alberta, Canada). To test intraexaminer and interexaminer reliabilities, semiautomatic segmentation was repeated 3 times by 1 examiner and then by 3 examiners...
October 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27684818/chest-ct-with-iterative-reconstruction-algorithms-for-airway-stent-evaluation-in-patients-with-malignant-obstructive-tracheobronchial-diseases
#18
Tingting Li, Yonggao Zhang, Yadong Wang, Jianbo Gao, Yan Jiang
The aim of the study was to investigate the image quality of low-dose CT images with different reconstruction algorithms including filtered back projection (FBP), hybrid iterative reconstruction (HIR), and iterative model reconstruction (IMR) algorithms by comparison of routine dose images with FBP reconstruction, in patients with malignant obstructive tracheobronchial diseases.In total, 60 patients (59 ± 9.3 years, 37 males) with airway stent who are randomly assigned into 2 groups (routine-dose [RD] and low-dose [LD] group, 30 for each) underwent chest CT on a 256-slice CT (RD-group 120 kV, 250 mAs, LD-group 120 kV, 120 mAs)...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27664878/innate-lymphoid-cells-a-paradigm-for-low-ssi-in%C3%A2-cleft-lip-repair
#19
Erika Simmerman, Xu Qin, Brendan Marshall, Libby Perry, Lei Cai, Tailing Wang, Jack Yu, Omid Akbari, Babak Baban
BACKGROUND: Cleft lip and palate reconstructions demonstrate significantly lower surgical site infection rates compared with clean-contaminated cases, prompting investigation into the pathophysiology causing this discrepancy. Recent studies have identified a new group of innate lymphocytes called innate lymphoid cells (ILCs), located in barrier surfaces of the skin, airways, and intestine. Our objectives were to explore for the first time the presence of ILCs in the vermillion of neonates and young children undergoing cleft lip reconstruction and characterize their composition by measuring the three classes of ILCs...
October 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27645974/surgical-reconstruction-for-severe-tracheal-obstruction-in-morquio-a-syndrome
#20
Christian Pizarro, Ryan R Davies, Mary Theroux, Ellen A Spurrier, Lauren W Averill, Shunji Tomatsu
Progressive tracheal obstruction is commonly seen in Morquio A syndrome and can lead to life-threatening complications. Although tracheostomy can address severe upper airway obstruction, lower airway obstruction, commonly associated with a narrow thoracic inlet and vascular compression, requires an alternative approach. We describe the case of a 16-year-old patient with Morquio A syndrome whose near-fatal tracheal obstruction was relieved by timely surgical tracheal vascular reconstruction with dramatic resolution of his respiratory symptoms...
October 2016: Annals of Thoracic Surgery
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