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https://www.readbyqxmd.com/read/28930774/high-levels-of-cerebrospinal-fluid-chemokines-point-to-the-presence-of-neuroinflammation-in-peripheral-neuropathic-pain-a-cross-sectional-study-of-two-cohorts-of-patients-compared-to-healthy-controls
#1
Emmanuel Bäckryd, Anne-Li Lind, Måns Thulin, Anders Larsson, Björn Gerdle, Torsten Gordh
Animal models suggest that chemokines are important mediators in the pathophysiology of neuropathic pain. Indeed, these substances have been called "gliotransmitters", a term that illustrates the close interplay between glial cells and neurons in the context of neuroinflammation and pain. However, evidence in humans is scarce. The aim of the study was to determine a comprehensive cerebrospinal fluid (CSF) inflammatory profile for neuropathic pain patients. Our hypothesis was that we would thereby find indications of a postulated on-going process of central neuroinflammation...
September 18, 2017: Pain
https://www.readbyqxmd.com/read/28930222/add-on-complementary-medicine-in-cancer-care-evidence-in-literature-and-experiences-of-integration
#2
REVIEW
Elio Rossi, Mariella Di Stefano, Fabio Firenzuoli, Maria Valeria Monechi, Sonia Baccetti
Background: According to the literature an increasing number of cancer patients demand for complementary therapies during their disease. Research has demonstrated that some of these therapies are effective and safe as adjunctive treatments in specific symptoms of these patients. Methods: The aims of the paper are to review the main and recent papers of international literature on the effectiveness of complementary medicine (CM) therapies on side effects of anti-cancer protocols and improvement in the quality of life of oncological patients, and to describe the integration of evidence-based acupuncture, herbal medicine and homeopathy treatments in Public Cancer Network of the region of Tuscany...
January 24, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28928713/pain-in-people-with-multiple-sclerosis-associations-with-modifiable-lifestyle-factors-fatigue-depression-anxiety-and-mental-health-quality-of-life
#3
Claudia H Marck, Alysha M De Livera, Tracey J Weiland, Pia L Jelinek, Sandra L Neate, Chelsea R Brown, Keryn L Taylor, Fary Khan, George A Jelinek
BACKGROUND: People with multiple sclerosis (MS) often experience pain, which can interfere with mobility, employment, and quality of life (QOL). METHODS: This cross-sectional study explored associations between pain, demographic, disease, and modifiable lifestyle factors in an international sample of people with MS recruited online. RESULTS: Substantial pain, of moderate/severe intensity and interfering at least moderately with work/household or enjoyment of life in the past 4 weeks, was reported by 682/2,362 (28...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28923189/gender-differences-in-sleep-disorders-in-the-us-military
#4
Shannon N Foster, Shana L Hansen, Dale C Capener, Panagiotis Matsangas, Vincent Mysliwiec
OBJECTIVES: The purpose of this study is to compare sleep disorders between male and female military personnel. Comorbid behavioral health disorders and chronic pain were also studied in relation to sleep disorders. DESIGN: We conducted a retrospective review of military personnel who underwent a sleep medicine evaluation and an in-laboratory attended polysomnography. Initial sleep questionnaires, demographics, polysomnographic variables, and comorbid disorders of interest were reviewed and compared for each sex...
October 2017: Sleep Health
https://www.readbyqxmd.com/read/28922159/can-musical-or-painting-interventions-improve-chronic-pain-mood-quality-of-life-and-cognition-in-patients-with-mild-alzheimer-s-disease-evidence-from-a-randomized-controlled-trial
#5
Elodie Pongan, Barbara Tillmann, Yohana Leveque, Béatrice Trombert, Jean Claude Getenet, Nicolas Auguste, Virginie Dauphinot, Hanane El Haouari, Malou Navez, Jean-Michel Dorey, Pierre Krolak-Salmon, Bernard Laurent, Isabelle Rouch
BACKGROUND: Among non-pharmacological therapies, musical intervention is often used for patients with Alzheimer's disease (AD) and patients presenting with chronic pain. However, their efficacy is still under debate. OBJECTIVE: Our aim was to determine the efficacy of choral singing versus painting sessions on chronic pain, mood, quality of life, and cognition in AD patients. METHODS: In this multicenter randomized controlled trial, 59 mild AD patients were randomized to a 12-week singing (SG; n = 31) or painting group (PG; n = 28)...
September 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28921411/differences-in-the-severity-distress-interference-and-frequency-on-cancer-related-symptoms-between-island-hispanic-puerto-ricans-and-mainland-non-hispanic-whites
#6
Velda J González-Mercado, Leorey N Saligan, Ming Ji, Maureen Groer, Elsa Pedro, Susan McMillan
The knowledge base of cancer-related symptoms is increasing; yet, limited attention has been given to provide evidence on differences in the perception of cancer symptoms between ethnic groups, especially in the Hispanic Puerto Rican (PR) population. To examine whether there are significant differences in the severity, distress, interference, and frequency of cancer symptoms between island Hispanic PR and mainland non-Hispanic whites. In this secondary data analysis, data from 109 Hispanic PR was matched by age, gender and cancer diagnosis with data from non-Hispanic whites...
September 18, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28920050/management-of-chronic-daily-headache-and-psychiatric-co-morbidities-by-lifestyle-modification-participatory-action-research-combining-new-communication-media
#7
Fakhrudin Faizi, Abbas Tavallaee, Abolfazl Rahimi, Masoud Saghafinia
BACKGROUND: Lifestyle modification has a significant role in chronic daily headache (CDH) management. Participatory action research (PAR) can play an important role in managing chronic medical conditions. However, it has been scarcely used in CDH management. OBJECTIVES: This study aimed to empower patients with CDH to modify their lifestyle in order to reduce both their headache and related psychiatric co-morbidities in a multidisciplinary headache clinic at Baqiyatallah hospital, Tehran, IR Iran...
April 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/28919809/adequacy-of-cancer-related-pain-management-and-predictors-of-undertreatment-at-referral-to-a-pain-clinic
#8
Paulo Reis-Pina, Peter G Lawlor, António Barbosa
BACKGROUND: Several guidelines have advocated the need for adequate cancer-related pain (CRP) management. The pain management index (PMI) has been proposed as an auditable measure of the appropriateness for analgesic therapy. OBJECTIVES: To determine the adequacy of CRP management based on the PMI status and its patient-related predictors at the point of referral to a pain clinic (PC). METHODS: Consecutive patients referred to a PC had standardized initial assessments and status documentation on the Brief Pain Inventory (BPI) ratings; pain mechanism, using a neuropathic pain diagnostic questionnaire (the Douleur Neuropathique 4 tool); episodic pain; oral morphine equivalent daily dose; the Hospital Anxiety Depression Scale and the Emotion Thermometer scores; and cancer diagnosis, metastases, treatment, and pain duration...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28919766/cognitive-behavioral-therapy-for-somatic-symptom-disorders-in-later-life-a-prospective-comparative-explorative-pilot-study-in-two-clinical-populations
#9
Michelle Jh Verdurmen, Arjan C Videler, Astrid M Kamperman, David Khasho, Christina M van der Feltz-Cornelis
BACKGROUND: Elderly patients with somatic symptom disorder (SSD) put a great burden on the health care delivery system. Cognitive behavioral therapy (CBT) is effective in adults with SSD. However, no studies have been conducted yet into CBT for SSD in later life. OBJECTIVES: We explored the feasibility of CBT for SSD in the elderly. METHODS: This is a prospective pilot study comparing two outpatient specialty mental health settings for adults (<60 years; n=13) and for elderly patients (≥60 years; n=9) with SSD...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28919117/global-regional-and-national-incidence-prevalence-and-years-lived-with-disability-for-328-diseases-and-injuries-for-195-countries-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#10
(no author information available yet)
BACKGROUND: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016. METHODS: We estimated prevalence and incidence for 328 diseases and injuries and 2982 sequelae, their non-fatal consequences...
September 16, 2017: Lancet
https://www.readbyqxmd.com/read/28918186/health-related-quality-of-life-in-melanoma-patients-impact-of-melanoma-related-limb-lymphoedema
#11
Caroline A Gjorup, Mogens Groenvold, Helle W Hendel, Karin Dahlstroem, Krzysztof T Drzewiecki, Tobias W Klausen, Lisbet R Hölmich
AIM: To explore health-related quality of life (HRQoL) in recurrence-free melanoma patients, with a focus on the association between melanoma-related limb lymphoedema and HRQoL. METHODS: HRQoL was evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the breast cancer module (EORTC QLQ-BR23) subscales body image and future perspective, the Functional Assessment for Cancer Therapy-General subscale social/family well-being and the Hospital Anxiety and Depression Scale...
September 14, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28916991/higher-physical-activity-and-lower-pain-levels-before-surgery-predict-non-improvement-of-knee-pain-1%C3%A2-year-after-tka
#12
Nikolai Kornilov, Maren Falch Lindberg, Caryl Gay, Alexander Saraev, Taras Kuliaba, Leiv Arne Rosseland, Anners Lerdal
PURPOSE: The purpose of this study was to describe patterns of pain during the first year following total knee arthroplasty (TKA) and evaluate pre- and postoperative factors associated with pain and patient satisfaction at 1 year. It was hypothesized that more severe preoperative pain would be associated with more residual pain and lower patient satisfaction 1 year after surgery. METHODS: A longitudinal cohort study was performed with repeated measures of pain (0-10 numeric rating scale) and evaluation of other self-reported symptoms (Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, and Fatigue Severity Score), daily functioning (Lawton Instrumental Activities of Daily Living Scale), quality of life (EQ-5D-3L), knee function (KSS Knee and Function Score), perioperative and clinical characteristics (e...
September 15, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28916294/characteristics-of-older-adults-in-primary-care-who-may-benefit-from-primary-palliative-care-in-the-united-states
#13
Nancy Dudley, Christine S Ritchie, Margaret I Wallhagen, Kenneth E Covinsky, Bruce A Cooper, Kanan Patel, Irena Stijacic-Cenzer, Susan A Chapman
CONTEXT: Older adults with advanced illness and associated symptoms may benefit from primary palliative care, but limited data exist to identify older adults in U.S. primary care to benefit from this care. OBJECTIVES: To describe U.S. primary care visits among adults 65 years and older with advanced illness. METHODS: Cross-sectional analysis of the National Ambulatory and Hospital Ambulatory Medical Care Surveys (2009-2011) was conducted using chi-square tests to compare visits without and with advanced illness to U...
September 12, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28914999/the-art-of-caring-in-health-care-settings-the-arts-and-creative-arts-therapies-help-patients-and-their-caregivers-express-themselves-and-find-relief-from-pain-anxiety-and-depression
#14
https://www.readbyqxmd.com/read/28905376/hiv-and-headache-a-cross-sectional-study
#15
Pedro Augusto Sampaio Rocha-Filho, Rinailda Cascia Santos Torres, Ulisses Ramos Montarroyos
INTRODUCTION: The head and neck are the second most common locations for pain among HIV-positive individuals. Most studies were conducted among HIV patients at an advanced stage of the disease. METHODS: This was a cross-sectional study. Patients with HIV and CD4+ T lymphocyte counts >500 were included. Semi-structured interview, the Headache Impact Test (HIT-6), and the Hospital Anxiety and Depression Scale were used. RESULTS: Of the 119 cases included, 63% were men...
September 14, 2017: Headache
https://www.readbyqxmd.com/read/28901169/predictors-of-response-to-occipital-nerve-stimulation-in-refractory-chronic-headache
#16
Sarah Miller, Laurence Watkins, Manjit Matharu
Background Occipital nerve stimulation is a promising treatment for refractory chronic headache disorders, but is invasive and costly. Identifying predictors of response would be useful in selecting patients. We present the results of an open-label prospective cohort study of 100 patients (35 chronic migraine, 33 chronic cluster headache, 20 short-lasting unilateral neuralgiform headache attacks and 12 hemicrania continua) undergoing occipital nerve stimulation, using a multivariate binary regression analysis to identify predictors of response...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28899603/anaemia-but-not-iron-deficiency-is-associated-with-clinical-symptoms-and-quality-of-life-in-patients-with-severe-heart-failure-and-palliative-home-care-a-substudy-of-the-prefer-trial
#17
Kurt Boman, Mona Olofsson, Ann-Charlotte R Bergman, Margareta Brännström
BACKGROUND: To explore the relationships between anaemia or iron deficiency (ID) and symptoms, quality of life (QoL), morbidity, and mortality. METHODS: A post-hoc, non-prespecified, explorative substudy of the prospective randomized PREFER trial. One centre study of outpatients with severe HF and palliative need managed with advanced home care. Associations between anaemia, ID, and the Edmonton Symptom Assessment Scale (ESAS), Euro QoL (EQ-5D), Kansas City Cardiomyopathy Questions (KCCQ) were examined only at baseline but at 6months for morbidity and mortality...
September 9, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28895999/-quality-of-life-and-associated-characteristics-of-restless-legs-syndrome-in-the-adult-population-of-burgos-spain
#18
M T Barroso-Perez, E Cubo, J Cordero-Guevara, E Poza-Maure, L Checa-Diez
INTRODUCTION: Restless legs syndrome (RLS) is a neurological disorder with a prevalence of up to 15%, although little is known about its impact upon quality of life. AIM: To analyse the impact of RLS on health-related quality of life. SUBJECTS AND METHODS: A descriptive cross-sectional study. A random sample of 1,275 subjects over 18 years old, stratified by age, was taken from the urban area of Burgos, with an estimated prevalence, 10%; alpha, 5%; accuracy, 3%; and losses, 70%, using a two-phase study (screening and diagnosis of cases of RLS and non-cases confirmed by a doctor)...
September 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28895484/patterns-relevance-and-predictors-of-heart-failure-dyadic-symptom-appraisal
#19
Christopher S Lee, James O Mudd, Jonathan Auld, Jill M Gelow, Shirin O Hiatt, Christopher V Chien, Julie T Bidwell, Karen S Lyons
BACKGROUND: Caregivers are thought to play a major role in helping patients first appraise and then respond to heart failure (HF) symptoms. AIMS: The aims of this study were to: (a) characterise distinct patterns of HF patient-caregiver dyads with respect to symptom appraisal; and (b) link dyadic symptom appraisal to contributions to self-care and caregiver strain. METHODS AND RESULTS: A cross-sectional dyadic descriptive design was used to capture patient and caregiver appraisal of patient HF symptoms (i...
October 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28894703/health-related-quality-of-life-and-mental-health-of-elderly-by-occupational-status
#20
Yeunhee Kwak, Yoonjung Kim
BACKGROUND: This study aimed to identify the association between health-related quality of life and mental health by elderly Koreans' occupational status. METHODS: This descriptive cross-sectional study consisted of a secondary analysis of data from the Korea National Health and Nutrition Examination Survey V-3 (2012). The sample comprised 1431 people aged 65 yr and older. RESULTS: Compared to participants employed, those not showed lower HRQOL...
August 2017: Iranian Journal of Public Health
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