keyword
https://read.qxmd.com/read/38441996/assessment-of-patients-with-head-and-neck-cancer-using-the-md-anderson-dysphagia-inventory-results-of-a-study-into-its-comprehensiveness-comprehensibility-and-relevance-to-clinical-practice
#21
JOURNAL ARTICLE
Kate Toft, Catherine Best, Jayne Donaldson
BACKGROUND: The MD Anderson Dysphagia Inventory (MDADI) is a widely used patient-reported outcome measure (PROM) which assesses dysphagia-related quality of life (QoL) in head and neck cancer (HNC). Despite its common use in HNC research and clinical practice, few of its psychometric properties have been reappraised since its inception. The aim of this study was to perform a survey-based qualitative analysis of UK HNC clinicians' perceptions of the content validity of the MDADI, evaluating it across the parameters of relevance, comprehensiveness and comprehensibility as per the COSMIN guideline for PROM assessment...
March 5, 2024: International Journal of Language & Communication Disorders
https://read.qxmd.com/read/38440650/osteosarcoma-of-head-and-neck-region-tertiary-cancer-care-center-experience
#22
JOURNAL ARTICLE
K S Sandeep, Priyank Rathod, Raisha Dalvi, Ajinkya Pawar, Salahudheen Thottiyen, Shashank Pandya, Mohit Sharma, Shailesh Patel, Vikas Warikoo, Shivam Pandya
Head and neck osteosarcoma is an uncommon yet aggressive tumor which presents therapeutic challenges to get favourable results. Surgery remained the most effective treatment modality in this entity eventhough chemoradiotherapy have been tried in various studies for better outcome but still not yet becomes the standard in the management of these cases unlike in extremity osteosarcoma. We present our experience in the management of this uncommon yet lethal malignant tumor, i.e. head and neck osteosarcoma. To study the clinicopathological and prognostic features of Osteosarcoma in head and neck subsite...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440426/-chemotherapy-for-salivary-gland-malignant-carcinoma-meta-analysis-and-systemic-review
#23
JOURNAL ARTICLE
Kritant Bhushan, Mansi Luthra Sharma, Deepak Kumar Gupta
 The primary form of treatment for salivary gland cancer is surgical resection. Radiation therapy is used as adjuvant therapy in cases of aggressive tumours, currently patients with recurrent or metastatic cancer who are not suitable for surgery or radiation are most often treated with chemotherapy. PRISMA guidelines for systematic reviews were followed to evaluate salivary gland malignancies involving cytotoxic chemotherapy and biologic agents. An electronic literature search of Medline, PubMed, Scopus, etc...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440157/evidence-summary-on-managing-radiotherapy-induced-oral-mucositis-in-patients-with-head-and-neck-cancer
#24
REVIEW
Zimo Zhang, Li Tian, Juan Liu, Hua Jiang, Panfeng Wang
OBJECTIVE: To summarize the best evidence for managing radiotherapy-induced oral mucositis in patients with head and neck cancer, and improve the quality of care. METHODS: According to the "6S" evidence pyramid model, we searched local and other part of world published clinical guidelines, expert consensus, evidence summary, and systematic review. The literature quality assessment followed the Appraisal of Guidelines for Research and Evaluation (AGREE II). for guidelines, AMSTAR-2 for systematic reviews, and Joanna Briggs Institute (JBI) Evidence-Based Health Care Center's quality evaluation tool for expert opinions and expert consensus articles...
March 2024: Asia-Pacific Journal of Oncology Nursing
https://read.qxmd.com/read/38422830/treatment-package-time%C3%A2-%C3%A2-14%C3%A2-weeks-improves-recurrence-free-and-disease-specific-survival-in-hpv-positive-opc-with-high-risk-features
#25
JOURNAL ARTICLE
Manasa Melachuri, Chareeni Kurukulasuriya, Purva Rumde, Terral Patel, Daniel Awad, Seungwon Kim, Robert Ferris, Shaum Sridharan, Umamaheswar Duvvuri
BACKGROUND: Guidelines recommend treatment package time < 85 days and time from surgery to radiation initiation < 6 weeks in head and neck cancer patients. However, HPV positive primaries treated with TORS and adjuvant radiotherapy traditionally demonstrate favorable outcomes. METHODS: Single center retrospective chart review of patients diagnosed with HPV positive treatment naïve primary squamous cell carcinoma treated with TORS and postoperative radiation therapy with or without Chemotherapy from 2012 to 2022 with data collection from December 2022-April 2023...
February 28, 2024: Oral Oncology
https://read.qxmd.com/read/38421392/exploring-the-landscape-of-ai-assisted-decision-making-in-head-and-neck-cancer-treatment-a-comparative-analysis-of-nccn-guidelines-and-chatgpt-responses
#26
JOURNAL ARTICLE
Filippo Marchi, Elisa Bellini, Andrea Iandelli, Claudio Sampieri, Giorgio Peretti
PURPOSE: Recent breakthroughs in natural language processing and machine learning, exemplified by ChatGPT, have spurred a paradigm shift in healthcare. Released by OpenAI in November 2022, ChatGPT rapidly gained global attention. Trained on massive text datasets, this large language model holds immense potential to revolutionize healthcare. However, existing literature often overlooks the need for rigorous validation and real-world applicability. METHODS: This head-to-head comparative study assesses ChatGPT's capabilities in providing therapeutic recommendations for head and neck cancers...
February 29, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38420716/measuring-financial-toxicity-in-head-and-neck-cancer-a-systematic-review
#27
REVIEW
Elisa Raggini, Davide Mattavelli, Gabriele Zigliani, Paolo Bossi, Cesare Piazza
OBJECTIVE: The current study systematically reviews the literature about financial toxicity (FT) in head and neck cancer patients. Three databases were reviewed: PubMed, Scopus and Web of Science. METHODS: Full text English papers published from 2000 to 2022 reporting on quantitative results about FT in head and neck cancer survivors collected through structured questionnaires or interviews were included. RESULTS: Twenty-seven articles were included...
February 2024: Acta Otorhinolaryngologica Italica
https://read.qxmd.com/read/38416070/risk-factors-for-postoperative-delirium-in-patients-undergoing-major-head-and-neck-cancer-surgery-a-meta-analysis
#28
JOURNAL ARTICLE
Jiaqi Sun, Ying Ji, Jingsi Huang, Hong Zhao
BACKGROUND: Postoperative delirium (POD) is a common and serious complication after extensive surgery. Understanding the independent and potential modifiable risk factors leading to POD in patients with head and neck cancer (HNC) can provide information for future intervention trials aimed at reducing this risk. OBJECTIVE: To systematically analyze influencing factors of POD in patients with HNC and identify high-risk individuals for delirium. METHODS: PubMed, EMBASE, Scopus, OVID, and Cochrane Library were searched for publications prior to June 2023...
February 26, 2024: Cancer Nursing
https://read.qxmd.com/read/38381151/global-frequency-and-distribution-of-head-and-neck-sarcomas-in-adulthood-a-systematic-review
#29
JOURNAL ARTICLE
Giuditta Mannelli, Sara Bassani, Ginevra Cosi, Matteo Fermi, Luca Gazzini, Carlotta Liberale, Luca Mazzetti, Giampiero Parrinello, Alberto Maria Saibene, Gabriele Molteni, Lara Valentina Comini
PURPOSE: Head and neck sarcomas (HNS) constitute a rare and heterogeneous cancer entity. Management remains a challenge due their rarity and different biological behaviour among tens of subtypes. This systematic review aimed to describe HNS global frequency and distribution in adulthood. METHODS: A systematic review was performed using PICOTS search strategies for qualitative question and it was written in accordance with PRISMA 2020 Statement. 70,653 publications were identified, and 15 variables were evaluated for a total of 2428 patients...
February 21, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38371216/is-using-the-harmonic-scalpel-better-than-conventional-hemostasis-in-neck-dissection-a-meta-analysis
#30
JOURNAL ARTICLE
Ishaque Hameed, Mohammad Omer Khan, Syed Abdus Samad, Samar Mahmood, Omer Mustafa Siddiqui, Indallah Hameed, Muhammad Nashit, Ayman Iqbal, Shayan Marsia, Al Haitham Al Shetawi
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: The clinical decision to pursue harmonic scalpel (HS) method vs conventional hemostasis to treat head and neck cancers has been arguably predicated on the clinical outcomes observed. This study aims to evaluate the surgical outcomes of neck dissection between both techniques and perform an updated meta-analysis using the available literature. METHODS: We searched PubMed, Scopus, and Cochrane Library through 31st December 2021, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
March 2024: Craniomaxillofacial Trauma & Reconstruction
https://read.qxmd.com/read/38370678/quantifying-the-seed-sensitivity-of-cancer-subclonal-reconstruction-algorithms
#31
Philippa L Steinberg, Lydia Y Liu, Anna Neiman-Golden, Yash Patel, Paul C Boutros
BACKGROUND: Intra-tumoural heterogeneity complicates cancer prognosis and impairs treatment success. One of the ways subclonal reconstruction (SRC) quantifies intra-tumoural heterogeneity is by estimating the number of subclones present in bulk DNA sequencing data. SRC algorithms are probabilistic and need to be initialized by a random seed. However, the seeds used in bioinformatics algorithms are rarely reported in the literature. Thus, the impact of the initializing seed on SRC solutions has not been studied...
February 8, 2024: bioRxiv
https://read.qxmd.com/read/38368851/ameloblastic-carcinoma-a-systematic-review
#32
REVIEW
Liam Robinson, Lucas Guimarães Abreu, Felipe Paiva Fonseca, Keith D Hunter, Melvin A Ambele, Willie F P van Heerden
BACKGROUND: Ameloblastic carcinoma (AC) is the most common odontogenic malignancy, constituting approximately 30% of cases in this category. Literature is sparse on malignant odontogenic neoplasms, with a large proportion of current knowledge derived from case reports or small case series. METHODS: A systematic review of case series/case reports of AC was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) Statement guidelines...
February 18, 2024: Journal of Oral Pathology & Medicine
https://read.qxmd.com/read/38365701/the-association-of-hbv-infection-and-head-and-neck-cancer-a-systematic-review-and-meta-analysis
#33
JOURNAL ARTICLE
Rukeng Tan, Xinyu Zhu, Yutong Sun, Shihao Yang, Chao Peng, Xinkai Feng, Zengyu Chen, Yiliyaer Yimamu, Guiqing Liao, Le Yang
BACKGROUND: Hepatitis B virus (HBV) infections is an important public health problem worldwide and closely affect extrahepatic cancer. Several recent studies have investigated the relationship between HBV infection and head and neck cancer (HNC), but their findings were inconsistent.In order to address the limitations of small sample sizes, we conducted a meta-analysis to assess the association between HBV and HNC. METHODS: We systematically searched PubMed, Web of Science, Embase, Scopus, Cochrane Library, and China National Knowledge Infrastructure from inception to August 2023...
February 16, 2024: BMC Cancer
https://read.qxmd.com/read/38356437/patient-reported-outcome-measures-for-dysphagia-in-head-and-neck-cancer-a-systematic-review-and-appraisal-of-content-validity-and-internal-structure
#34
REVIEW
Beatrice Manduchi, Zhiyao Che, Jolie G Ringash, Margaret I Fitch, Doris Howell, Rosemary Martino
Dysphagia is a major head and neck cancer (HNC) issue. Dysphagia-related patient-reported outcome measures (PROMs) are critical for patient-centred assessment and intervention tailoring. This systematic review aimed to derive a comprehensive inventory of HNC dysphagia PROMs and appraise their content validity and internal structure. Six electronic databases were searched to February 2023 for studies detailing PROM content validity or internal structure. Eligible PROMs were those developed or validated for HNC, with ≥20% of items related to swallowing...
April 2024: Head & Neck
https://read.qxmd.com/read/38350785/prehabilitation-for-patients-with-cancer-undergoing-radiation-therapy-a-scoping-review
#35
JOURNAL ARTICLE
E Harris, L Marignol
AIMS: Prehabilitation is a process of identifying and assessing factors that could compromise the physical and psychological health of patients undergoing cancer treatment and implementing an intervention to combat such concerns. The use of prehabilitation in cancer surgery has yielded positive outcomes in rectal, lung and abdominal cancers. Prehabilitation strategies have potential to improve the management of patients receiving radiation therapy or chemoradiation. The aim of the present study was to map the evidence of the assessment and evaluation of prehabilitation for radiation therapy patients...
February 8, 2024: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/38344842/lymph-node-yield-impact-on-oncologic-outcomes-in-oral-cavity-cancer
#36
JOURNAL ARTICLE
Carlos Khalil, Mark Khoury, Kevin Higgins, Danny Enepekides, Irene Karam, Zain Ali Husain, Andrew Bayley, Ian Poon, Tra Truong, Kelvin K W Chan, Martin Smoragiewicz, Rui Fu, Antoine Eskander
BACKGROUND: Lymph node metastases are associated with poor prognosis in oral cavity squamous cell carcinoma (OCSCC). In other cancers, clinical guidelines on the number of lymph nodes removed during primary surgery, lymph node yield (LNY), exist. Here, we evaluated the prognostic capacity of LNY on regional failure, locoregional recurrence, and disease-free survival (DFS) in patients with OCSCC treated by primary neck surgery. METHODS: This retrospective cohort study took place at Sunnybrook Health Sciences Centre in Toronto, Canada and involved a chart review of all adult patients with treatment-naive OCSCC undergoing primary neck dissection...
February 12, 2024: Head & Neck
https://read.qxmd.com/read/38341629/survival-outcomes-of-temporal-bone-squamous-cell-carcinoma-a-systematic-review-and-meta-analysis
#37
REVIEW
Krystelle Sioufi, Aaron David Haynes, Paul W Gidley, Anastasios Maniakas, Dianna Roberts, Marc-Elie Nader
OBJECTIVE: Temporal bone squamous cell carcinoma (TBSCC) is a rare malignancy with poor prognosis, and optimal treatment for advanced cases is uncertain. Our systematic literature review aimed to assess 5-year survival outcomes for advanced TBSCC across different treatment modalities. DATA SOURCES: EMBASE, Medline, PubMed, and Web of Science. REVIEW METHODS: A systematic literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for articles published between January 1989 and June 2023...
February 11, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38339415/management-of-cutaneous-squamous-cell-carcinoma-of-the-scalp-the-role-of-imaging-and-therapeutic-approaches
#38
REVIEW
Júlia Verdaguer-Faja, Agustí Toll, Aram Boada, Álvaro Guerra-Amor, Carla Ferrándiz-Pulido, Ane Jaka
Cutaneous squamous cell carcinoma (cSCC) is the second most common subtype of skin cancer. The scalp is one of the most frequently affected locations and is associated with a higher rate of complications, compared to other locations. In addition, it has a characteristic thickness and anatomical structure that may influence both growth pattern and treatment of primary cSCC; while clinical peripheral margins may be easily achieved during the surgery, vertical excision of the tumor is limited by the skull. Despite having a unique anatomy, current guidelines do not contemplate specific recommendations for scalp cSCC, which leads to inconsistent decision-making in multidisciplinary committees when discussing tumors with high risk factors or with close margins...
February 4, 2024: Cancers
https://read.qxmd.com/read/38331679/digastric-and-sternocleidomastoid-muscle-flaps-after-conservative-total-parotidectomy-for-cancer-a-care-case-report
#39
JOURNAL ARTICLE
F Haroun, Q Lisan, H Mirghani, O Laccourreye
OBJECTIVE: To describe, according to the CARE guidelines, an easily reproducible technique using two local muscle flaps to reduce the unsightly retromandibular hollow left by total parotidectomy for cancer. CASE DESCRIPTION: A 40-year-old Caucasian male with T3N1M0 temporal skin melanoma was managed by skin resection, conservative total parotidectomy and ipsilateral level II-IV selective lymph-node dissection. Two rotational muscle flaps were taken from the ipsilateral posterior belly of the digastric and sternocleidomastoid muscles...
February 7, 2024: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://read.qxmd.com/read/38327762/the-remove-the-mask-open-source-head-and-neck-surface-guided-radiation-therapy-system
#40
JOURNAL ARTICLE
Youssef Ben Bouchta, Mark Gardner, Chandrima Sengupta, Julia Johnson, Paul Keall
BACKGROUND AND PURPOSE: Surface Guided Radiotherapy (SGRT) for head and neck radiotherapy is challenging as obstructions are common and non-rigid facial motion can compromise surface accuracy. The purpose of this work was to develop and benchmark the Remove the Mask (RtM) SGRT system, an open-source system especially designed to address the challenges faced in radiotherapy of head and neck cancer. MATERIALS AND METHODS: The accuracy of the RtM SGRT system was benchmarked using a head phantom positioned on a robotic motion platform capable of sub-millimetre accuracy which was used to induce unidirectional shifts and to reproduce three real head motion traces...
January 2024: Physics and Imaging in Radiation Oncology
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