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Head neck cancer guidelines

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https://www.readbyqxmd.com/read/27909090/alcohol-intake-and-risk-of-incident-melanoma-a-pooled-analysis-of-three-prospective-studies-in-the-united-states
#1
Andrew Rivera, Hongmei Nan, Tricia Li, Abrar Qureshi, Eunyoung Cho
BACKGROUND: Alcohol consumption is associated with increased risk of numerous cancers, but existing evidence for an association with melanoma is equivocal. No study has evaluated the association with different anatomic locations of melanoma. METHODS: We used data from three large prospective cohort studies to investigate whether alcohol intake was associated with risk of melanoma. Alcohol intake was assessed repeatedly by food-frequency questionnaires. A Cox proportional hazards model was used to calculate multivariate-adjusted hazard ratios (HRs)...
December 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27898198/ahns-series-do-you-know-your-guidelines-principles-of-treatment-for-nasopharyngeal-cancer-a-review-of-the-national-comprehensive-cancer-network-guidelines
#2
Zhen Gooi, Jeremy Richmon, Nishant Agrawal, Elizabeth Blair, Louis Portugal, Everett Vokes, Tanguy Seiwert, Jonas de Souza, Vassiliki Saloura, Daniel Haraf, David Goldenberg, Jason Chan
This article is a continuation of the "Do You Know Your Guidelines" series, an initiative of the American Head and Neck Society's Education Committee to increase awareness of current best practices pertaining to head and neck cancer. The National Comprehensive Cancer Network guidelines for the management of nasopharyngeal cancer are reviewed here in a systematic fashion. These guidelines outline the workup, treatment and surveillance of patients with nasopharyngeal cancer. © 2016 Wiley Periodicals, Inc. Head Neck, 2016...
November 29, 2016: Head & Neck
https://www.readbyqxmd.com/read/27890427/internal-and-external-generalizability-of-temporal-dose-response-relationships-for-xerostomia-following-imrt-for-head-and-neck-cancer
#3
Maria Thor, Adepitan A Owosho, Haley D Clark, Jung Hun Oh, Nadeem Riaz, Allan Hovan, Jillian Tsai, Steven D Thomas, Sae Hee K Yom, Jonn S Wu, Joseph M Huryn, Vitali Moiseenko, Nancy Y Lee, Cherry L Estilo, Joseph O Deasy
BACKGROUND AND PURPOSE: To study internal and external generalizability of temporal dose-response relationships for xerostomia after intensity-modulated radiotherapy (IMRT) for head and neck cancer, and to investigate potential amendments of the QUANTEC guidelines. MATERIAL AND METHODS: Objective xerostomia was assessed in 121 patients (nCohort1=55; nCohort2=66) treated to 70Gy@2Gy in 2006-2015. Univariate and multivariate analyses (UVA, MVA with 1000 bootstrap populations) were conducted in Cohort1, and generalizability of the best-performing MVA model was investigated in Cohort2 (performance: AUC, p-values, and Hosmer-Lemeshow p-values (pHL))...
November 24, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27884018/blood-transfusion-during-radical-chemo-radiotherapy-does-not-reduce-tumour-hypoxia-in-squamous-cell-cancer-of-the-head-and-neck
#4
Liam Welsh, Rafal Panek, Angela Riddell, Kee Wong, Martin O Leach, Mahvash Tavassoli, Durdana Rahman, Maria Schmidt, Tara Hurley, Lorna Grove, Thomas Richards, Dow-Mu Koh, Christopher Nutting, Kevin Harrington, Kate Newbold, Shreerang Bhide
BACKGROUND: Patients with head and neck squamous cell carcinoma (HNSCC) undergoing radical chemo-radiation (CRT) frequently receive transfusion with packed red cells (PRCT) during radiotherapy on the basis that PRCT increases tumour oxygenation and overcomes hypoxia-induced radio-resistance. This is likely to be a significant oversimplification given the fact that tumour hypoxia is the result of several intrinsic and extrinsic factors, including many that are not directly related to serum haemoglobin (Hb)...
November 24, 2016: British Journal of Cancer
https://www.readbyqxmd.com/read/27882625/review-of-high-risk-features-of-cutaneous-squamous-cell-carcinoma-and-discrepancies-between-the-american-joint-committee-on-cancer-and-nccn-clinical-practice-guidelines-in-oncology
#5
REVIEW
Samuel Lamarre Skulsky, Barry O'Sullivan, Orla McArdle, Mary Leader, Muireann Roche, Peter J Conlon, James Paul O'Neill
Cutaneous squamous cell carcinoma (SCC) is a malignancy that arises from epidermal keratinocytes. Although the majority of cutaneous SCC cases are easily treated without further complication, some behave more aggressively and carry a poor prognosis. These "high-risk" cutaneous SCCs commonly originate in the head and neck and have an increased tendency toward recurrence, local invasion, and distant metastasis. Factors for high-risk cutaneous SCC include large size (>2 cm), a deeply invasive lesion (>2 mm), incomplete excision, high-grade/desmoplastic lesions, perineural invasion (PNI), lymphovascular invasion, immunosuppression, and high-risk anatomic locations...
November 24, 2016: Head & Neck
https://www.readbyqxmd.com/read/27865537/metastases-in-the-cervical-spine-from-primary-head-and-neck-cancers-current-concepts-of-diagnosis-and-management
#6
S D Colbert, S Ramakrishna, J R Harvey, P A Brennan
Vertebral metastases from primary head and neck cancers are uncommon, and so there are no clear guidelines about management. The spinal cord can be compressed by a vertebral fracture or invasion of a tumour, and may present as an oncological and spinal emergency. The goals of treatment are to relieve pain and maintain neurological function. However, surgical treatments in this group of patients have not been defined, and primary operative treatment of spinal metastases remains controversial. Here we discuss their contemporary management...
November 16, 2016: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27846019/posttreatment-surveillance-for-sinonasal-malignancy
#7
Alan D Workman, James N Palmer, Nithin D Adappa
PURPOSE OF REVIEW: Sinonasal neoplasms have a high rate of recurrence following treatment, and clinicians utilize a variety of surveillance techniques. Generally, surveillance modality and frequency of follow-up are determined by the guidelines for head and neck cancer as a broad category. However, recent studies have demonstrated that a more tailored approach to follow-up may be necessary. RECENT FINDINGS: Endoscopy has low sensitivity in recurrence detection, especially in the asymptomatic patient...
November 14, 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27843342/the-danish-head-and-neck-cancer-database
#8
REVIEW
Jens Overgaard, Aleksandar Jovanovic, Christian Godballe, Jesper Grau Eriksen
AIM OF THE DATABASE: The Danish Head and Neck Cancer database is a nationwide clinical quality database that contains prospective data collected since the early 1960s. The overall aim of this study was to describe the outcome of the national strategy for multidisciplinary treatment of head and neck cancer in Denmark and to create a basis for clinical trials. STUDY POPULATION: The study population consisted of all Danish patients referred for treatment of squamous cell carcinoma of the larynx, pharynx, oral cavity, or neck nodes from unknown primary or any histopathological type (except lymphoma) of cancer in the nasal sinuses, salivary glands, or thyroid gland (corresponding to the International Classification of Diseases, tenth revision, classifications C...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27842990/review-of-sentinel-node-procedure-in-cn0-head-and-neck-squamous-cell-carcinomas-guidelines-from-the-french-evaluation-cooperative-subgroup-of-gettec
#9
R Garrel, G Poissonnet, S Temam, G Dolivet, N Fakhry, D de Raucourt
The reliability of the sentinel lymph node (SN) technique has been established for more than ten years in T1-T2 oral cavity and oropharynx squamous cell carcinoma. Although most authors stress the necessity of rigorous implementation, there are no agreed guidelines. Moreover, other indications have been described, in other anatomical areas of the upper aerodigestive tract and in case of previous surgery or radiotherapy. SN expert teams, under the GETTEC head and neck tumor study group, conducted a review of the key points for implementation in head and neck cancers through guidelines and a review of classical and extended indications...
November 11, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/27832255/association-of-postoperative-radiotherapy-with-survival-in-patients-with-n1-oral-cavity-and-oropharyngeal-squamous-cell-carcinoma
#10
Michelle M Chen, Jeremy P Harris, Wendy Hara, Davud Sirjani, Vasu Divi
Importance: The guidelines for head and neck cancer recommend consideration of adjuvant postoperative radiotherapy (PORT) for patients with pT1N1 or pT2N1 disease in the absence of other adverse features. This recommendation was recently changed for oropharyngeal (OP) squamous cell carcinoma (SCC). Objective: To examine the use and outcomes of PORT for N1 OP SCC and oral cavity (OC) SCC. Design, Setting, and Participants: This retrospective cohort study identified 1467 adult patients with OC SCC and 790 patients with OP SCC with pT1N1 or pT2N1 disease in the absence of other adverse features from the National Cancer Database from January 1, 2004, to December 31, 2013...
November 10, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27822049/prevalence-and-related-factors-of-psychological-distress-among-cancer-inpatients-using-routine-distress-thermometer-and-chinese-health-questionnaire-screening
#11
Yu-Jie Chiou, Nien-Mu Chiu, Liang-Jen Wang, Shau-Hsuan Li, Chun-Yi Lee, Ming-Kung Wu, Chien-Chih Chen, Yi-Shan Wu, Yu Lee
BACKGROUND: Clinical practice guidelines suggest routine screening for distress among cancer patients for immediate early psychiatric care. However, previous studies focusing on routine screening for psychological distress among cancer inpatients in Taiwan are scant. Thus, the aim of this study was to evaluate the prevalence and related factors of psychological distress and mental illness among cancer inpatients in Taiwan. PATIENTS AND METHODS: This study was conducted as a retrospective chart review in a general hospital in southern Taiwan...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27802200/modern-molecular-biomarkers-of-head-and-neck-cancer-part-i-epigenetic-diagnostics-and-prognostics-systematic-review
#12
Gintaras Juodzbalys, David Kasradze, Marco Cicciù, Aurimas Sudeikis, Laurynas Banys, Pablo Galindo-Moreno, Zygimantas Guobis
INTRODUCTION: Nearly half of the head and neck cancer cases are diagnosed in late stages. Traditional screening modalities have many disadvantages. The aim of the present article was to review the scientific literature about novel head and neck cancer diagnostics - epigenetic biomarkers. EVIDENCE ACQUISITION: A comprehensive review of the current literature was conducted according to the PRISMA guidelines by accessing the NCBI PubMed database. Authors conducted the search of articles in English language published from 2004 to 2015...
September 30, 2016: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/27717219/comprehensive-management-of-recurrent-thyroid-cancer-an-american-head-and-neck-society-consensus-statement-ahns-consensus-statement
#13
Joseph Scharpf, Michael Tuttle, Richard Wong, Drew Ridge, Russell Smith, Dana Hartl, Robert Levine, Gregory Randolph
This American Head and Neck Society (AHNS) consensus statement focuses on the detection and management of recurrent thyroid cancer. This document describes the radiologic approach to defining structural recurrent disease and the operative and nonoperative rationale in addressing identified structural disease to create equipoise in the personalized treatment strategy for the patient. The recommendations of this AHNS multidisciplinary consensus panel of the American Head and Neck Society are intended to help guide all multidisciplinary clinicians who diagnose or manage adult patients with thyroid cancer...
December 2016: Head & Neck
https://www.readbyqxmd.com/read/27699532/hpv-testing-of-head-and-neck-cancer-in-clinical-practice
#14
Max Robinson
The pathology laboratory has a central role in providing human papillomavirus (HPV) tests for patients with head and neck cancer. There is an extensive literature around HPV testing and a large number of proprietary HPV tests, which makes the field difficult to navigate. This review provides a concise contemporary overview of the evidence around HPV testing in head and neck cancer and signposts key publications, guideline documents and the most commonly used methods in clinical practice.
2017: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27695934/the-development-of-an-icf-based-clinical-guideline-and-screening-tool-for-the-standardized-assessment-and-evaluation-of-functioning-after-head-and-neck-cancer-treatment
#15
Ulrich Kisser, Christine Adderson-Kisser, Michaela Coenen, Marita Stier-Jarmer, Sven Becker, Carla Sabariego, Ulrich Harréus
The assessment and evaluation of functioning and quality of life after tumor treatment in head and neck cancer (HNC) are considered as essential aspects of clinical routine and studies. A huge number of instruments are available that have been designed to evaluate functioning and quality of life after HNC treatment. The diversity of these instruments in terms of content, response options and administration hinders the comparability of available studies and the performance of meta-analyses. The objective of this paper is to inform about the development of a screening tool for the standardized assessment and evaluation of functioning based on the International Classification of Functioning, Disability and Health (ICF) Core Set for HNC...
September 30, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27688109/geographic-variation-in-medicare-treatment-costs-and-outcomes-for-advanced-head-and-neck-cancer
#16
Vasu Divi, Li Tao, Alice Whittemore, Ingrid Oakley-Girvan
BACKGROUND: Advanced head and neck cancer (HNC) is a complex group of diseases that requires the input and coordination of multiple providers. While there are general guidelines for treatment, there is also considerable variation in how patients are treated, and how long they survive after treatment. It is unclear how the treatment variations relate to treatment costs and survival. METHODS: We identified 3678 Medicare patients with advanced HNC treated in 12 US regions between 2004 and 2009 using the linked database containing Medicare and Surveillance Epidemiology and End Results (SEER) data...
October 2016: Oral Oncology
https://www.readbyqxmd.com/read/27642003/oral-and-oropharyngeal-cancer-and-the-role-of-sexual-behaviour-a-systematic-review
#17
James A Chancellor, Sally J Ioannides, James M Elwood
OBJECTIVES: This systematic review identified and evaluated the evidence for the role of sexual behaviours in the development of oropharyngeal cancers (OPCs) and oral cavity cancers (OCCs). METHODS: Following the PRISMA guidelines, we identified observational and interventional studies reporting associations between several different sexual behaviours and OPC or OCC. Study quality was assessed independently by two reviewers using a validated scoring system. RESULTS: From 513 papers identified, 21, reporting on 20 studies, fulfilled the inclusion criteria...
September 19, 2016: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/27641220/increasing-use-of-nonsurgical-therapy-in-advanced-stage-oral-cavity-cancer-a-population-based-study
#18
Richard B Cannon, Justin C Sowder, Luke O Buchmann, Jason P Hunt, Ying J Hitchcock, Shane Lloyd, Kenneth F Grossman, Marcus M Monroe
BACKGROUND: National guidelines support surgical-based treatment and offer nonsurgical therapy as an alternative for advanced-stage oral cavity squamous cell carcinoma (SCC). There are limited data evaluating current utilization of these therapies and their survival outcomes. METHODS: A total of 5856 patients were found in the Surveillance, Epidemiology, and End Results (SEER) database from 1988 to 2008 with resectable advanced-stage oral cavity SCC tumors. Outcomes were disease-specific survival (DSS) and overall survival (OS)...
September 19, 2016: Head & Neck
https://www.readbyqxmd.com/read/27633327/peer-review-of-radiotherapy-planning-quantifying-outcomes-and-a-proposal-for-prospective-data-collection
#19
J Mackenzie, G Graham, I A Olivotto
AIMS: The Canadian Partnership for Quality Radiotherapy quality assurance guidelines recommend that radiation oncologist peer review of curative radiotherapy plans takes place ideally before the first fraction of treatment is delivered. This study documented and evaluated the outcomes of weekly, disease site-specific, radiotherapy peer review, quality assurance rounds at the Tom Baker Cancer Centre in Calgary, Canada with a view to making recommendations about the optimal timing and documentation of peer review during the radiotherapy planning processes...
September 12, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27577420/applying-the-snomed-ct-concept-model-to-represent-value-sets-for-head-and-neck-cancer-documentation
#20
Anne Randorff Højen, Dorthe Brønnum, Kirstine Rosenbeck Gøeg, Pia Britt Elberg
This paper presents an analysis of the extent to which SNOMED CT is suitable for representing data within the domain of head and neck cancer. In this analysis we assess whether the concept model of SNOMED CT comply with the documentation needed within this clinical domain. Attributes from the follow-up template of the clinical quality registry for Danish Head and Neck Cancer, and their respective value sets were mapped to SNOMED CT using existing mapping guidelines. Results show that post-coordination is important to represent specific types of value sets, such as absence of findings and severities...
2016: Studies in Health Technology and Informatics
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